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Total number of protein in "GO:0032355" GO term:  123

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ADCYAP1R1_ENST00000304166 ADCYAP1R1 P41586 Pituitary adenylate cyclase-activating polypeptide type I receptor chr7 GO:0032355 Not Cancer Driver No 127 0.271 0 0 0.0 0
AGT AGT P01019 Angiotensinogen chr1 GO:0032355 Not Cancer Driver No 85 0.179 33 10 0.303 1
AIFM1 AIFM1 O95831 Apoptosis-inducing factor 1, mitochondrial chrX GO:0032355 Not Cancer Driver No 88 0.144 166 22 0.133 11
ALDH1A2 ALDH1A2 O94788 Retinal dehydrogenase 2 chr15 GO:0032355 Not Cancer Driver No 100 0.193 56 13 0.232 0
ANXA1_ENST00000257497 ANXA1 P04083 Annexin A1 chr9 GO:0032355 Not Cancer Driver No 59 0.171 61 12 0.197 0
APOB APOB P04114 Apolipoprotein B-100 chr2 GO:0032355 Not Cancer Driver No 1022 0.224 315 72 0.229 3
AQP4 AQP4 P55087 Aquaporin-4 chr18 GO:0032355 Not Cancer Driver No 50 0.155 30 9 0.3 0
AREG AREG P15514 Amphiregulin chr4 GO:0032355 Not Cancer Driver No 28 0.111 149 20 0.134 0
ARPC1B_ENST00000431816 ARPC1B O15143 Actin-related protein 2/3 complex subunit 1B chr7 GO:0032355 Not Cancer Driver No 37 0.099 34 1 0.029 0
ASS1_ENST00000352480 ASS1 P00966 Argininosuccinate synthase chr9 GO:0032355 Not Cancer Driver No 65 0.158 63 8 0.127 86
BAD_ENST00000309032 BAD Q92934 Bcl2-associated agonist of cell death chr11 GO:0032355 Not Cancer Driver No 14 0.083 163 14 0.086 0
BCL2L11 BCL2L11 O43521 Bcl-2-like protein 11 chr2 GO:0032355 Not Cancer Driver No 42 0.212 130 17 0.131 0
BCL2L2 BCL2L2 Q92843 Bcl-2-like protein 2 chr14 GO:0032355 Not Cancer Driver No 22 0.114 34 6 0.176 0
BMP7 BMP7 P18075 Bone morphogenetic protein 7 chr20 GO:0032355 Not Cancer Driver No 91 0.211 69 18 0.261 0
CALR CALR P27797 Calreticulin chr19 GO:0032355 Census Yes 45 0.108 245 31 0.127 0
CASP3 CASP3 P42574 Caspase-3 chr4 GO:0032355 Census Yes 32 0.116 62 5 0.081 0
CASP8_ENST00000432109 CASP8 Q14790 Caspase-8 chr2 GO:0032355 Census, Compendium Yes 142 0.296 106 12 0.113 1
CASP9 CASP9 P55211 Caspase-9 chr1 GO:0032355 Census Yes 49 0.118 71 7 0.099 0
CAT CAT P04040 Catalase chr11 GO:0032355 Not Cancer Driver No 70 0.133 176 18 0.102 0
CCDC62 CCDC62 Q6P9F0 Coiled-coil domain-containing protein 62 chr12 GO:0032355 Not Cancer Driver No 104 0.152 344 56 0.163 0
CCN2 CCN2 P29279 CCN family member 2 chr6 GO:0032355 Not Cancer Driver No 58 0.166 0 0 0.0 0
CCNA2_ENST00000618014 CCNA2 P20248 Cyclin-A2 chr4 GO:0032355 Not Cancer Driver No 45 0.104 186 19 0.102 0
CCND1 CCND1 P24385 G1/S-specific cyclin-D1 chr11 GO:0032355 Census, Compendium Yes 55 0.186 31 25 0.806 0
CD38 CD38 P28907 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 chr4 GO:0032355 Not Cancer Driver No 54 0.18 3 1 0.333 0
CDKN1B CDKN1B P46527 Cyclin-dependent kinase inhibitor 1B chr12 GO:0032355 Census, Compendium Yes 19 0.096 198 19 0.096 0
CFLAR CFLAR O15519 CASP8 and FADD-like apoptosis regulator chr2 GO:0032355 Not Cancer Driver No 40 0.083 44 2 0.045 0
COL1A1 COL1A1 P02452 Collagen alpha-1(I) chain chr17 GO:0032355 Census, Compendium Yes 247 0.169 1212 214 0.177 148
CRHBP CRHBP P24387 Corticotropin-releasing factor-binding protein chr5 GO:0032355 Not Cancer Driver No 61 0.189 0 0 0.0 0
CRYAB_ENST00000616970 CRYAB P02511 Alpha-crystallin B chain chr11 GO:0032355 Not Cancer Driver No 22 0.126 59 11 0.186 4
CSN1S1 CSN1S1 P47710 Alpha-S1-casein chr4 GO:0032355 Not Cancer Driver No 31 0.168 109 16 0.147 0
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 GO:0032355 Census, Compendium Yes 415 0.531 288 301 1.045 14
CYP19A1_ENST00000396404 CYP19A1 P11511 Aromatase chr15 GO:0032355 Not Cancer Driver No 91 0.181 2 1 0.5 5
CYP1B1 CYP1B1 Q16678 Cytochrome P450 1B1 chr2 GO:0032355 Not Cancer Driver No 61 0.112 31 3 0.097 40
DHH DHH O43323 Desert hedgehog protein chr12 GO:0032355 Not Cancer Driver No 36 0.091 57 7 0.123 1
DNMT3A DNMT3A Q9Y6K1 DNA (cytosine-5)-methyltransferase 3A chr2 GO:0032355 Census, Compendium Yes 194 0.213 371 59 0.159 16
EGFR EGFR P00533 Epidermal growth factor receptor chr7 GO:0032355 Census, Compendium Yes 444 0.367 223 35 0.157 1
ENDOG ENDOG Q14249 Endonuclease G, mitochondrial chr9 GO:0032355 Not Cancer Driver No 11 0.037 61 1 0.016 0
ENO2 ENO2 P09104 Gamma-enolase chr12 GO:0032355 Not Cancer Driver No 48 0.111 12 2 0.167 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 GO:0032355 Census, Compendium Yes 121 0.203 195 27 0.138 2
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 GO:0032355 Not Cancer Driver No 90 0.17 92 11 0.12 1
ESRRA_ENST00000000442 ESRRA P11474 Steroid hormone receptor ERR1 chr11 GO:0032355 Compendium Yes 37 0.087 101 9 0.089 0
EZH2_ENST00000460911 EZH2 Q15910 Histone-lysine N-methyltransferase EZH2 chr7 GO:0032355 Census, Compendium Yes 120 0.161 284 44 0.155 11
F7 F7 P08709 Coagulation factor VII chr13 GO:0032355 Not Cancer Driver No 74 0.159 50 7 0.14 108
FAM210B FAM210B Q96KR6 Protein FAM210B, mitochondrial chr20 GO:0032355 Not Cancer Driver No 10 0.052 32 0 0.0 0
FGF10 FGF10 O15520 Fibroblast growth factor 10 chr5 GO:0032355 Not Cancer Driver No 56 0.269 34 11 0.324 2
FOXA1 FOXA1 P55317 Hepatocyte nuclear factor 3-alpha chr14 GO:0032355 Census, Compendium Yes 100 0.212 295 53 0.18 0
GH1 GH1 P01241 Somatotropin chr17 GO:0032355 Not Cancer Driver No 54 0.249 24 9 0.375 15
GHSR GHSR Q92847 Growth hormone secretagogue receptor type 1 chr3 GO:0032355 Not Cancer Driver No 85 0.232 4 0 0.0 2
GJB2_ENST00000382848 GJB2 P29033 Gap junction beta-2 protein chr13 GO:0032355 Not Cancer Driver No 34 0.15 0 0 0.0 46
GPER1 GPER1 Q99527 G-protein coupled estrogen receptor 1 chr7 GO:0032355 Not Cancer Driver No 65 0.173 13 5 0.385 0
GPI_ENST00000644934 GPI P06744 Glucose-6-phosphate isomerase chr19 GO:0032355 Not Cancer Driver No 77 0.138 73 11 0.151 24
GPX1_ENST00000620890 GPX1 P07203 Glutathione peroxidase 1 chr3 GO:0032355 Not Cancer Driver No 38 0.187 12 1 0.083 0
GPX4_ENST00000616066 GPX4 P36969 Phospholipid hydroperoxide glutathione peroxidase chr19 GO:0032355 Not Cancer Driver No 14 0.071 0 0 0.0 0
H2AFZ H2AZ1 P0C0S5 Histone H2A.Z chr4 GO:0032355 Not Cancer Driver No 23 0.18 71 16 0.225 0
HNRNPD HNRNPD Q14103 Heterogeneous nuclear ribonucleoprotein D0 chr4 GO:0032355 Not Cancer Driver No 39 0.11 206 19 0.092 0
HPGD HPGD P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] chr4 GO:0032355 Not Cancer Driver No 32 0.12 4 1 0.25 2
HSF1 HSF1 Q00613 Heat shock factor protein 1 chr8 GO:0032355 Not Cancer Driver No 59 0.112 335 37 0.11 0
HTR5A HTR5A P47898 5-hydroxytryptamine receptor 5A chr7 GO:0032355 Not Cancer Driver No 174 0.487 6 1 0.167 0
IGF1R IGF1R P08069 Insulin-like growth factor 1 receptor chr15 GO:0032355 Not Cancer Driver No 183 0.134 265 37 0.14 6
IGFBP2 IGFBP2 P18065 Insulin-like growth factor-binding protein 2 chr2 GO:0032355 Not Cancer Driver No 32 0.098 171 24 0.14 0
IHH IHH Q14623 Indian hedgehog protein chr2 GO:0032355 Not Cancer Driver No 58 0.141 111 15 0.135 6
IL10 IL10 P22301 Interleukin-10 chr1 GO:0032355 Not Cancer Driver No 19 0.107 23 1 0.043 0
ITGA2 ITGA2 P17301 Integrin alpha-2 chr5 GO:0032355 Not Cancer Driver No 166 0.141 26 0 0.0 0
KAT5_ENST00000377046 KAT5 Q92993 Histone acetyltransferase KAT5 chr11 GO:0032355 Not Cancer Driver No 65 0.127 173 21 0.121 3
KIF18A KIF18A Q8NI77 Kinesin-like protein KIF18A chr11 GO:0032355 Not Cancer Driver No 114 0.127 405 60 0.148 0
LCOR LCOR Q96JN0 Ligand-dependent corepressor chr10 GO:0032355 Not Cancer Driver No 54 0.125 388 46 0.119 0
LEP LEP P41159 Leptin chr7 GO:0032355 Not Cancer Driver No 29 0.174 0 0 0.0 2
MAP1B MAP1B P46821 Microtubule-associated protein 1B chr5 GO:0032355 Not Cancer Driver No 332 0.135 1947 278 0.143 0
MBD2 MBD2 Q9UBB5 Methyl-CpG-binding domain protein 2 chr18 GO:0032355 Not Cancer Driver No 26 0.063 384 25 0.065 0
MBD3 MBD3 O95983 Methyl-CpG-binding domain protein 3 chr19 GO:0032355 Not Cancer Driver No 50 0.172 246 46 0.187 0
MMP15 MMP15 P51511 Matrix metalloproteinase-15 chr16 GO:0032355 Not Cancer Driver No 78 0.117 205 23 0.112 0
MMP2 MMP2 P08253 72 kDa type IV collagenase chr16 GO:0032355 Not Cancer Driver No 123 0.186 29 6 0.207 2
MSX2 MSX2 P35548 Homeobox protein MSX-2 chr5 GO:0032355 Not Cancer Driver No 27 0.101 168 14 0.083 4
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 GO:0032355 Census, Compendium Yes 80 0.182 299 46 0.154 0
MYOD1 MYOD1 P15172 Myoblast determination protein 1 chr11 GO:0032355 Census Yes 45 0.141 246 33 0.134 0
MYOG MYOG P15173 Myogenin chr1 GO:0032355 Not Cancer Driver No 36 0.161 132 20 0.152 0
NCOA3 NCOA3 Q9Y6Q9 Nuclear receptor coactivator 3 chr20 GO:0032355 Not Cancer Driver No 176 0.124 1231 160 0.13 0
NCOR2 NCOR2 Q9Y618 Nuclear receptor corepressor 2 chr12 GO:0032355 Census, Compendium Yes 373 0.148 2355 356 0.151 0
NQO1 NQO1 P15559 NAD(P)H dehydrogenase [quinone] 1 chr16 GO:0032355 Not Cancer Driver No 21 0.077 10 1 0.1 0
NR2F2 NR2F2 P24468 COUP transcription factor 2 chr15 GO:0032355 Not Cancer Driver No 66 0.159 101 1 0.01 5
NRIP1_ENST00000400199 NRIP1 P48552 Nuclear receptor-interacting protein 1 chr21 GO:0032355 Not Cancer Driver No 141 0.122 998 124 0.124 0
OGG1_ENST00000344629 OGG1 O15527 N-glycosylase/DNA lyase chr3 GO:0032355 Not Cancer Driver No 37 0.107 71 12 0.169 0
OPRL1_ENST00000336866 OPRL1 P41146 Nociceptin receptor chr20 GO:0032355 Not Cancer Driver No 81 0.219 0 0 0.0 0
OXT OXT P01178 Oxytocin-neurophysin 1 chr20 GO:0032355 Not Cancer Driver No 10 0.08 0 0 0.0 0
OXTR OXTR P30559 Oxytocin receptor chr3 GO:0032355 Not Cancer Driver No 46 0.118 18 0 0.0 0
PAM_ENST00000438793 PAM P19021 Peptidyl-glycine alpha-amidating monooxygenase chr5 GO:0032355 Not Cancer Driver No 129 0.133 254 37 0.146 0
PCNA PCNA P12004 Proliferating cell nuclear antigen chr20 GO:0032355 Not Cancer Driver No 30 0.115 22 3 0.136 1
PDGFA PDGFA P04085 Platelet-derived growth factor subunit A chr7 GO:0032355 Not Cancer Driver No 31 0.147 75 10 0.133 0
PDGFRB PDGFRB P09619 Platelet-derived growth factor receptor beta chr5 GO:0032355 Census, Compendium Yes 164 0.148 231 44 0.19 7
PENK_ENST00000451791 PENK P01210 Proenkephalin-A chr8 GO:0032355 Not Cancer Driver No 109 0.408 142 62 0.437 0
POU4F1 POU4F1 Q01851 POU domain, class 4, transcription factor 1 chr13 GO:0032355 Not Cancer Driver No 51 0.122 273 34 0.125 1
POU4F2 POU4F2 Q12837 POU domain, class 4, transcription factor 2 chr4 GO:0032355 Not Cancer Driver No 130 0.318 308 87 0.282 0
PPP1R9B PPP1R9B Q96SB3 Neurabin-2 chr17 GO:0032355 Not Cancer Driver No 47 0.058 695 35 0.05 0
PTCH1 PTCH1 Q13635 Protein patched homolog 1 chr9 GO:0032355 Census, Compendium Yes 243 0.168 382 67 0.175 18
PTGFR PTGFR P43088 Prostaglandin F2-alpha receptor chr1 GO:0032355 Not Cancer Driver No 105 0.292 2 0 0.0 0
PTGS2 PTGS2 P35354 Prostaglandin G/H synthase 2 chr1 GO:0032355 Not Cancer Driver No 105 0.174 30 5 0.167 0
RAMP3 RAMP3 O60896 Receptor activity-modifying protein 3 chr7 GO:0032355 Not Cancer Driver No 30 0.203 0 0 0.0 0
RARA RARA P10276 Retinoic acid receptor alpha chr17 GO:0032355 Census, Compendium Yes 70 0.152 167 14 0.084 0
RUVBL2 RUVBL2 Q9Y230 RuvB-like 2 chr19 GO:0032355 Not Cancer Driver No 62 0.134 100 13 0.13 0
SFRP1 SFRP1 Q8N474 Secreted frizzled-related protein 1 chr8 GO:0032355 Not Cancer Driver No 40 0.127 39 7 0.179 0
SLC34A1 SLC34A1 Q06495 Sodium-dependent phosphate transport protein 2A chr5 GO:0032355 Not Cancer Driver No 92 0.144 46 8 0.174 9
SLC6A1_ENST00000643498 SLC6A1 P30531 Sodium- and chloride-dependent GABA transporter 1 chr3 GO:0032355 Not Cancer Driver No 119 0.199 24 9 0.375 4
SLC6A4_ENST00000401766 SLC6A4 P31645 Sodium-dependent serotonin transporter chr17 GO:0032355 Not Cancer Driver No 101 0.16 73 12 0.164 0
SOCS2_ENST00000536696 SOCS2 O14508 Suppressor of cytokine signaling 2 chr12 GO:0032355 Not Cancer Driver No 32 0.162 61 2 0.033 0
SPRR2A SPRR2A P35326 Small proline-rich protein 2A chr1 GO:0032355 Not Cancer Driver No 20 0.278 0 0 0.0 0
SRD5A1 SRD5A1 P18405 3-oxo-5-alpha-steroid 4-dehydrogenase 1 chr5 GO:0032355 Not Cancer Driver No 35 0.135 0 0 0.0 0
SSTR1 SSTR1 P30872 Somatostatin receptor type 1 chr14 GO:0032355 Not Cancer Driver No 96 0.246 50 12 0.24 0
SSTR2 SSTR2 P30874 Somatostatin receptor type 2 chr17 GO:0032355 Not Cancer Driver No 54 0.146 22 7 0.318 0
SSTR3 SSTR3 P32745 Somatostatin receptor type 3 chr22 GO:0032355 Not Cancer Driver No 94 0.225 110 26 0.236 0
STAT3 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 GO:0032355 Census, Compendium Yes 110 0.143 152 15 0.099 19
STAT5B STAT5B P51692 Signal transducer and activator of transcription 5B chr17 GO:0032355 Census, Compendium Yes 93 0.118 144 19 0.132 5
STRN3 STRN3 Q13033 Striatin-3 chr14 GO:0032355 Not Cancer Driver No 93 0.117 366 42 0.115 0
STXBP1_ENST00000373299 STXBP1 P61764 Syntaxin-binding protein 1 chr9 GO:0032355 Not Cancer Driver No 97 0.163 111 23 0.207 18
TACR1 TACR1 P25103 Substance-P receptor chr2 GO:0032355 Not Cancer Driver No 69 0.17 28 2 0.071 0
TACR3 TACR3 P29371 Neuromedin-K receptor chr4 GO:0032355 Not Cancer Driver No 137 0.295 31 17 0.548 5
TGFB1 TGFB1 P01137 Transforming growth factor beta-1 proprotein chr19 GO:0032355 Not Cancer Driver No 41 0.105 41 4 0.098 10
TH TH P07101 Tyrosine 3-monooxygenase chr11 GO:0032355 Not Cancer Driver No 61 0.116 149 21 0.141 38
TXNIP TXNIP Q9H3M7 Thioredoxin-interacting protein chr1 GO:0032355 Not Cancer Driver No 61 0.156 77 14 0.182 0
UCN UCN P55089 Urocortin chr2 GO:0032355 Not Cancer Driver No 7 0.056 61 4 0.066 0
UGT1A1 UGT1A1 P22309 UDP-glucuronosyltransferase 1A1 chr2 GO:0032355 Not Cancer Driver No 100 0.188 11 2 0.182 55
WNT7A WNT7A O00755 Protein Wnt-7a chr3 GO:0032355 Not Cancer Driver No 93 0.266 18 9 0.5 4
WNT8B WNT8B Q93098 Protein Wnt-8b chr10 GO:0032355 Not Cancer Driver No 50 0.142 27 5 0.185 0
ZNF703 ZNF703 Q9H7S9 Zinc finger protein 703 chr8 GO:0032355 Not Cancer Driver No 26 0.044 415 14 0.034 0