Total number of protein in "GO:0032271" GO term: 104
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABL1_ENST00000318560 | ABL1 | P00519 | Tyrosine-protein kinase ABL1 | chr9 | GO:0032271 | Census, Compendium | Yes | 139 | 0.123 | 604 | 73 | 0.121 | 2 |
| ADD1_ENST00000398129 | ADD1 | P35611 | Alpha-adducin | chr4 | GO:0032271 | Not Cancer Driver | No | 106 | 0.144 | 439 | 64 | 0.146 | 0 |
| ADD2_ENST00000407644 | ADD2 | P35612 | Beta-adducin | chr2 | GO:0032271 | Not Cancer Driver | No | 157 | 0.216 | 423 | 104 | 0.246 | 0 |
| ADD3 | ADD3 | Q9UEY8 | Gamma-adducin | chr10 | GO:0032271 | Not Cancer Driver | No | 95 | 0.135 | 381 | 48 | 0.126 | 1 |
| AKAP9 | AKAP9 | Q99996 | A-kinase anchor protein 9 | chr7 | GO:0032271 | Census | Yes | 474 | 0.121 | 2281 | 268 | 0.117 | 1 |
| AMBRA1_ENST00000458649 | AMBRA1 | Q9C0C7 | Activating molecule in BECN1-regulated autophagy protein 1 | chr11 | GO:0032271 | Not Cancer Driver | No | 173 | 0.133 | 788 | 103 | 0.131 | 0 |
| ANKRD53 | ANKRD53 | Q8N9V6 | Ankyrin repeat domain-containing protein 53 | chr2 | GO:0032271 | Not Cancer Driver | No | 57 | 0.108 | 252 | 21 | 0.083 | 0 |
| ARHGEF7 | ARHGEF7 | Q14155 | Rho guanine nucleotide exchange factor 7 | chr13 | GO:0032271 | Not Cancer Driver | No | 106 | 0.132 | 301 | 39 | 0.13 | 0 |
| ARL2 | ARL2 | P36404 | ADP-ribosylation factor-like protein 2 | chr11 | GO:0032271 | Not Cancer Driver | No | 19 | 0.103 | 0 | 0 | 0.0 | 1 |
| ARL3 | ARL3 | P36405 | ADP-ribosylation factor-like protein 3 | chr10 | GO:0032271 | Not Cancer Driver | No | 16 | 0.088 | 0 | 0 | 0.0 | 2 |
| AVIL | AVIL | O75366 | Advillin | chr12 | GO:0032271 | Not Cancer Driver | No | 91 | 0.111 | 138 | 17 | 0.123 | 2 |
| CAMSAP1 | CAMSAP1 | Q5T5Y3 | Calmodulin-regulated spectrin-associated protein 1 | chr9 | GO:0032271 | Not Cancer Driver | No | 208 | 0.13 | 1129 | 158 | 0.14 | 0 |
| CAMSAP2 | CAMSAP2 | Q08AD1 | Calmodulin-regulated spectrin-associated protein 2 | chr1 | GO:0032271 | Not Cancer Driver | No | 176 | 0.118 | 1025 | 127 | 0.124 | 0 |
| CAMSAP3_ENST00000160298 | CAMSAP3 | Q9P1Y5 | Calmodulin-regulated spectrin-associated protein 3 | chr19 | GO:0032271 | Not Cancer Driver | No | 132 | 0.106 | 889 | 81 | 0.091 | 0 |
| CAPG_ENST00000409724 | CAPG | P40121 | Macrophage-capping protein | chr2 | GO:0032271 | Not Cancer Driver | No | 45 | 0.129 | 95 | 7 | 0.074 | 0 |
| CAPZA1 | CAPZA1 | P52907 | F-actin-capping protein subunit alpha-1 | chr1 | GO:0032271 | Not Cancer Driver | No | 40 | 0.14 | 41 | 2 | 0.049 | 0 |
| CAPZA2 | CAPZA2 | P47755 | F-actin-capping protein subunit alpha-2 | chr7 | GO:0032271 | Not Cancer Driver | No | 37 | 0.129 | 19 | 0 | 0.0 | 0 |
| CAPZA3 | CAPZA3 | Q96KX2 | F-actin-capping protein subunit alpha-3 | chr12 | GO:0032271 | Not Cancer Driver | No | 87 | 0.291 | 0 | 0 | 0.0 | 0 |
| CAPZB_ENST00000375142 | CAPZB | P47756 | F-actin-capping protein subunit beta | chr1 | GO:0032271 | Not Cancer Driver | No | 33 | 0.119 | 66 | 3 | 0.045 | 0 |
| CARMIL1 | CARMIL1 | Q5VZK9 | F-actin-uncapping protein LRRC16A | chr6 | GO:0032271 | Not Cancer Driver | No | 171 | 0.125 | 537 | 87 | 0.162 | 0 |
| CARMIL2 | CARMIL2 | Q6F5E8 | Capping protein, Arp2/3 and myosin-I linker protein 2 | chr16 | GO:0032271 | Not Cancer Driver | No | 154 | 0.107 | 669 | 75 | 0.112 | 4 |
| CAV3 | CAV3 | P56539 | Caveolin-3 | chr3 | GO:0032271 | Not Cancer Driver | No | 27 | 0.179 | 0 | 0 | 0.0 | 25 |
| CDH5 | CDH5 | P33151 | Cadherin-5 | chr16 | GO:0032271 | Not Cancer Driver | No | 144 | 0.184 | 305 | 55 | 0.18 | 0 |
| CDK5R1 | CDK5R1 | Q15078 | Cyclin-dependent kinase 5 activator 1 | chr17 | GO:0032271 | Not Cancer Driver | No | 35 | 0.114 | 103 | 16 | 0.155 | 0 |
| CDK5RAP2 | CDK5RAP2 | Q96SN8 | CDK5 regulatory subunit-associated protein 2 | chr9 | GO:0032271 | Not Cancer Driver | No | 217 | 0.115 | 1136 | 128 | 0.113 | 0 |
| CDKN1B | CDKN1B | P46527 | Cyclin-dependent kinase inhibitor 1B | chr12 | GO:0032271 | Census, Compendium | Yes | 19 | 0.096 | 198 | 19 | 0.096 | 0 |
| CKAP5 | CKAP5 | Q14008 | Cytoskeleton-associated protein 5 | chr11 | GO:0032271 | Not Cancer Driver | No | 198 | 0.097 | 634 | 64 | 0.101 | 0 |
| CLASP1_ENST00000646274 | CLASP1 | Q7Z460 | CLIP-associating protein 1 | chr2 | GO:0032271 | Not Cancer Driver | No | 163 | 0.106 | 642 | 70 | 0.109 | 0 |
| CLIP1 | CLIP1 | P30622 | CAP-Gly domain-containing linker protein 1 | chr12 | GO:0032271 | Census, Compendium | Yes | 184 | 0.128 | 1194 | 136 | 0.114 | 0 |
| CLIP3_ENST00000593074 | CLIP3 | Q96DZ5 | CAP-Gly domain-containing linker protein 3 | chr19 | GO:0032271 | Not Cancer Driver | No | 78 | 0.143 | 218 | 22 | 0.101 | 0 |
| DCTN1 | DCTN1 | Q14203 | Dynactin subunit 1 | chr2 | GO:0032271 | Census | Yes | 172 | 0.135 | 817 | 111 | 0.136 | 11 |
| DMTN_ENST00000358242 | DMTN | Q08495 | Dematin | chr8 | GO:0032271 | Not Cancer Driver | No | 53 | 0.131 | 348 | 46 | 0.132 | 0 |
| DRG1 | DRG1 | Q9Y295 | Developmentally-regulated GTP-binding protein 1 | chr22 | GO:0032271 | Not Cancer Driver | No | 35 | 0.095 | 31 | 0 | 0.0 | 0 |
| DYRK1A_ENST00000644942 | DYRK1A | Q13627 | Dual specificity tyrosine-phosphorylation-regulated kinase 1A | chr21 | GO:0032271 | Not Cancer Driver | No | 135 | 0.177 | 447 | 73 | 0.163 | 0 |
| EML2_ENST00000245925 | EML2 | O95834 | Echinoderm microtubule-associated protein-like 2 | chr19 | GO:0032271 | Not Cancer Driver | No | 97 | 0.149 | 20 | 3 | 0.15 | 0 |
| EPS8_ENST00000645775 | EPS8 | Q12929 | Epidermal growth factor receptor kinase substrate 8 | chr12 | GO:0032271 | Not Cancer Driver | No | 106 | 0.129 | 459 | 54 | 0.118 | 0 |
| FES | FES | P07332 | Tyrosine-protein kinase Fes/Fps | chr15 | GO:0032271 | Census | Yes | 103 | 0.125 | 245 | 34 | 0.139 | 0 |
| FKBP4 | FKBP4 | Q02790 | Peptidyl-prolyl cis-trans isomerase FKBP4 | chr12 | GO:0032271 | Not Cancer Driver | No | 46 | 0.1 | 134 | 12 | 0.09 | 0 |
| FLII | FLII | Q13045 | Protein flightless-1 homolog | chr17 | GO:0032271 | Not Cancer Driver | No | 128 | 0.101 | 206 | 32 | 0.155 | 0 |
| GBA2 | GBA2 | Q9HCG7 | Non-lysosomal glucosylceramidase | chr9 | GO:0032271 | Not Cancer Driver | No | 96 | 0.104 | 157 | 12 | 0.076 | 3 |
| GIT1_ENST00000225394 | GIT1 | Q9Y2X7 | ARF GTPase-activating protein GIT1 | chr17 | GO:0032271 | Not Cancer Driver | No | 67 | 0.088 | 434 | 42 | 0.097 | 0 |
| GSN | GSN | P06396 | Gelsolin | chr9 | GO:0032271 | Not Cancer Driver | No | 76 | 0.097 | 316 | 28 | 0.089 | 2 |
| HSPA1A | HSPA1A | P0DMV8 | Heat shock 70 kDa protein 1A | chr6 | GO:0032271 | Not Cancer Driver | No | 24 | 0.037 | 200 | 13 | 0.065 | 0 |
| HSPA1B | HSPA1B | P0DMV9 | Heat shock 70 kDa protein 1B | chr6 | GO:0032271 | Not Cancer Driver | No | 15 | 0.023 | 200 | 5 | 0.025 | 0 |
| INPP5J | INPP5J | Q15735 | Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A | chr22 | GO:0032271 | Not Cancer Driver | No | 102 | 0.101 | 629 | 42 | 0.067 | 0 |
| KIAA1211 | CRACD | Q6ZU35 | Capping protein-inhibiting regulator of actin dynamics | chr4 | GO:0032271 | Not Cancer Driver | No | 245 | 0.199 | 1210 | 241 | 0.199 | 0 |
| LMOD1 | LMOD1 | P29536 | Leiomodin-1 | chr1 | GO:0032271 | Not Cancer Driver | No | 97 | 0.162 | 499 | 80 | 0.16 | 0 |
| LMOD2 | LMOD2 | Q6P5Q4 | Leiomodin-2 | chr7 | GO:0032271 | Not Cancer Driver | No | 94 | 0.172 | 451 | 79 | 0.175 | 0 |
| LMOD3_ENST00000489031 | LMOD3 | Q0VAK6 | Leiomodin-3 | chr3 | GO:0032271 | Not Cancer Driver | No | 99 | 0.177 | 456 | 84 | 0.184 | 1 |
| MAP1B | MAP1B | P46821 | Microtubule-associated protein 1B | chr5 | GO:0032271 | Not Cancer Driver | No | 332 | 0.135 | 1947 | 278 | 0.143 | 0 |
| MAP2 | MAP2 | P11137 | Microtubule-associated protein 2 | chr2 | GO:0032271 | Compendium | Yes | 367 | 0.201 | 1726 | 340 | 0.197 | 0 |
| MAPRE1 | MAPRE1 | Q15691 | Microtubule-associated protein RP/EB family member 1 | chr20 | GO:0032271 | Not Cancer Driver | No | 26 | 0.097 | 109 | 11 | 0.101 | 0 |
| MAPRE3 | MAPRE3 | Q9UPY8 | Microtubule-associated protein RP/EB family member 3 | chr2 | GO:0032271 | Not Cancer Driver | No | 37 | 0.132 | 120 | 16 | 0.133 | 0 |
| MAPT_ENST00000262410 | MAPT | P10636 | Microtubule-associated protein tau | chr17 | GO:0032271 | Not Cancer Driver | No | 128 | 0.169 | 750 | 126 | 0.168 | 18 |
| MECP2_ENST00000303391 | MECP2 | P51608 | Methyl-CpG-binding protein 2 | chrX | GO:0032271 | Not Cancer Driver | No | 75 | 0.154 | 483 | 74 | 0.153 | 46 |
| MET_ENST00000397752 | MET | P08581 | Hepatocyte growth factor receptor | chr7 | GO:0032271 | Census, Compendium | Yes | 226 | 0.163 | 62 | 15 | 0.242 | 19 |
| MTPN | MTPN | P58546 | Myotrophin | chr7 | GO:0032271 | Not Cancer Driver | No | 11 | 0.093 | 11 | 3 | 0.273 | 0 |
| NAV3 | NAV3 | Q8IVL0 | Neuron navigator 3 | chr12 | GO:0032271 | Not Cancer Driver | No | 699 | 0.293 | 1823 | 548 | 0.301 | 0 |
| NIN | NIN | Q8N4C6 | Ninein | chr14 | GO:0032271 | Census, Compendium | Yes | 239 | 0.114 | 1392 | 164 | 0.118 | 2 |
| NUMA1 | NUMA1 | Q14980 | Nuclear mitotic apparatus protein 1 | chr11 | GO:0032271 | Census, Compendium | Yes | 234 | 0.111 | 1864 | 203 | 0.109 | 0 |
| OCLN | OCLN | Q16625 | Occludin | chr5 | GO:0032271 | Not Cancer Driver | No | 54 | 0.103 | 244 | 21 | 0.086 | 1 |
| PAK1_ENST00000356341 | PAK1 | Q13153 | Serine/threonine-protein kinase PAK 1 | chr11 | GO:0032271 | Not Cancer Driver | No | 57 | 0.105 | 299 | 30 | 0.1 | 2 |
| PFN4 | PFN4 | Q8NHR9 | Profilin-4 | chr2 | GO:0032271 | Not Cancer Driver | No | 17 | 0.132 | 0 | 0 | 0.0 | 0 |
| PINK1 | PINK1 | Q9BXM7 | Serine/threonine-protein kinase PINK1, mitochondrial | chr1 | GO:0032271 | Not Cancer Driver | No | 57 | 0.098 | 99 | 13 | 0.131 | 23 |
| PRUNE1 | PRUNE1 | Q86TP1 | Exopolyphosphatase PRUNE1 | chr1 | GO:0032271 | Not Cancer Driver | No | 43 | 0.095 | 93 | 14 | 0.151 | 4 |
| PSRC1_ENST00000409138 | PSRC1 | Q6PGN9 | Proline/serine-rich coiled-coil protein 1 | chr1 | GO:0032271 | Not Cancer Driver | No | 30 | 0.083 | 361 | 30 | 0.083 | 0 |
| RAC1_ENST00000348035 | RAC1 | P63000 | Ras-related C3 botulinum toxin substrate 1 | chr7 | GO:0032271 | Census, Compendium | Yes | 66 | 0.344 | 2 | 1 | 0.5 | 6 |
| RANGRF | RANGRF | Q9HD47 | Ran guanine nucleotide release factor | chr17 | GO:0032271 | Not Cancer Driver | No | 10 | 0.054 | 42 | 5 | 0.119 | 0 |
| RDX_ENST00000343115 | RDX | P35241 | Radixin | chr11 | GO:0032271 | Not Cancer Driver | No | 71 | 0.122 | 297 | 37 | 0.125 | 1 |
| RPS3_ENST00000527446 | RPS3 | P23396 | 40S ribosomal protein S3 | chr11 | GO:0032271 | Not Cancer Driver | No | 22 | 0.091 | 48 | 4 | 0.083 | 0 |
| SCIN | SCIN | Q9Y6U3 | Scinderin | chr7 | GO:0032271 | Not Cancer Driver | No | 100 | 0.14 | 170 | 35 | 0.206 | 0 |
| SLAIN1_ENST00000466548 | SLAIN1 | Q8ND83 | SLAIN motif-containing protein 1 | chr13 | GO:0032271 | Not Cancer Driver | No | 62 | 0.109 | 485 | 58 | 0.12 | 0 |
| SLAIN2 | SLAIN2 | Q9P270 | SLAIN motif-containing protein 2 | chr4 | GO:0032271 | Not Cancer Driver | No | 62 | 0.107 | 562 | 60 | 0.107 | 0 |
| SLC39A12 | SLC39A12 | Q504Y0 | Zinc transporter ZIP12 | chr10 | GO:0032271 | Not Cancer Driver | No | 210 | 0.304 | 89 | 29 | 0.326 | 0 |
| SNCA_ENST00000506244 | SNCA | P37840 | Alpha-synuclein | chr4 | GO:0032271 | Not Cancer Driver | No | 21 | 0.15 | 107 | 13 | 0.121 | 5 |
| SPTA1_ENST00000368147 | SPTA1 | P02549 | Spectrin alpha chain, erythrocytic 1 | chr1 | GO:0032271 | Not Cancer Driver | No | 1046 | 0.432 | 707 | 294 | 0.416 | 21 |
| SPTAN1_ENST00000372731 | SPTAN1 | Q13813 | Spectrin alpha chain, non-erythrocytic 1 | chr9 | GO:0032271 | Not Cancer Driver | No | 315 | 0.127 | 980 | 114 | 0.116 | 0 |
| SPTBN1 | SPTBN1 | Q01082 | Spectrin beta chain, non-erythrocytic 1 | chr2 | GO:0032271 | Not Cancer Driver | No | 311 | 0.132 | 869 | 123 | 0.142 | 0 |
| SPTBN2 | SPTBN2 | O15020 | Spectrin beta chain, non-erythrocytic 2 | chr11 | GO:0032271 | Not Cancer Driver | No | 317 | 0.133 | 877 | 126 | 0.144 | 2 |
| SPTBN4_ENST00000598249 | SPTBN4 | Q9H254 | Spectrin beta chain, non-erythrocytic 4 | chr19 | GO:0032271 | Not Cancer Driver | No | 312 | 0.122 | 866 | 103 | 0.119 | 0 |
| SPTBN5 | SPTBN5 | Q9NRC6 | Spectrin beta chain, non-erythrocytic 5 | chr15 | GO:0032271 | Not Cancer Driver | No | 314 | 0.085 | 1274 | 118 | 0.093 | 0 |
| SPTB_ENST00000389721 | SPTB | P11277 | Spectrin beta chain, erythrocytic | chr14 | GO:0032271 | Not Cancer Driver | No | 328 | 0.153 | 562 | 70 | 0.125 | 7 |
| STMN1_ENST00000357865 | STMN1 | P16949 | Stathmin | chr1 | GO:0032271 | Not Cancer Driver | No | 15 | 0.101 | 149 | 15 | 0.101 | 0 |
| STMN2_ENST00000220876 | STMN2 | Q93045 | Stathmin-2 | chr8 | GO:0032271 | Not Cancer Driver | No | 34 | 0.19 | 122 | 23 | 0.189 | 0 |
| SVIL | SVIL | O95425 | Supervillin | chr10 | GO:0032271 | Not Cancer Driver | No | 308 | 0.139 | 1423 | 192 | 0.135 | 0 |
| TBCD | TBCD | Q9BTW9 | Tubulin-specific chaperone D | chr17 | GO:0032271 | Not Cancer Driver | No | 156 | 0.131 | 60 | 9 | 0.15 | 11 |
| TMOD1_ENST00000395211 | TMOD1 | P28289 | Tropomodulin-1 | chr9 | GO:0032271 | Not Cancer Driver | No | 41 | 0.114 | 195 | 29 | 0.149 | 0 |
| TMOD2 | TMOD2 | Q9NZR1 | Tropomodulin-2 | chr15 | GO:0032271 | Not Cancer Driver | No | 33 | 0.094 | 216 | 22 | 0.102 | 0 |
| TMOD3 | TMOD3 | Q9NYL9 | Tropomodulin-3 | chr15 | GO:0032271 | Not Cancer Driver | No | 40 | 0.114 | 190 | 24 | 0.126 | 0 |
| TMOD4 | TMOD4 | Q9NZQ9 | Tropomodulin-4 | chr1 | GO:0032271 | Not Cancer Driver | No | 37 | 0.107 | 218 | 22 | 0.101 | 0 |
| TMSB10 | TMSB10 | P63313 | Thymosin beta-10 | chr2 | GO:0032271 | Not Cancer Driver | No | 2 | 0.045 | 44 | 2 | 0.045 | 0 |
| TMSB15A | TMSB15A | P0CG34 | Thymosin beta-15A | chrX | GO:0032271 | Not Cancer Driver | No | 8 | 0.178 | 45 | 8 | 0.178 | 0 |
| TMSB15B | TMSB15B | P0CG35 | Thymosin beta-15B | chrX | GO:0032271 | Not Cancer Driver | No | 7 | 0.156 | 45 | 7 | 0.156 | 0 |
| TMSB4X_ENST00000380633 | TMSB4X | P62328 | Thymosin beta-4 | chrX | GO:0032271 | Census | Yes | 7 | 0.159 | 44 | 7 | 0.159 | 0 |
| TMSB4Y | TMSB4Y | O14604 | Thymosin beta-4, Y-chromosomal | chrY | GO:0032271 | Not Cancer Driver | No | 1 | 0.023 | 44 | 1 | 0.023 | 0 |
| TOGARAM1_ENST00000361577 | TOGARAM1 | Q9Y4F4 | TOG array regulator of axonemal microtubules protein 1 | chr14 | GO:0032271 | Not Cancer Driver | No | 230 | 0.134 | 703 | 101 | 0.144 | 3 |
| TRIOBP_ENST00000644935 | TRIOBP | Q9H2D6 | TRIO and F-actin-binding protein | chr22 | GO:0032271 | Not Cancer Driver | No | 386 | 0.163 | 2196 | 370 | 0.168 | 1 |
| TUBB4A | TUBB4A | P04350 | Tubulin beta-4A chain | chr19 | GO:0032271 | Not Cancer Driver | No | 91 | 0.205 | 61 | 16 | 0.262 | 2 |
| TWF1_ENST00000395510 | TWF1 | Q12792 | Twinfilin-1 | chr12 | GO:0032271 | Not Cancer Driver | No | 50 | 0.143 | 52 | 3 | 0.058 | 0 |
| TWF2 | TWF2 | Q6IBS0 | Twinfilin-2 | chr3 | GO:0032271 | Not Cancer Driver | No | 34 | 0.097 | 59 | 8 | 0.136 | 0 |
| VDAC2_ENST00000543351 | VDAC2 | P45880 | Voltage-dependent anion-selective channel protein 2 | chr10 | GO:0032271 | Not Cancer Driver | No | 35 | 0.119 | 9 | 1 | 0.111 | 0 |
| VIL1 | VIL1 | P09327 | Villin-1 | chr2 | GO:0032271 | Not Cancer Driver | No | 124 | 0.15 | 222 | 38 | 0.171 | 0 |
| VILL_ENST00000383759 | VILL | O15195 | Villin-like protein | chr3 | GO:0032271 | Not Cancer Driver | No | 100 | 0.117 | 222 | 28 | 0.126 | 0 |
| WASHC2C_ENST00000374362 | WASHC2C | Q9Y4E1 | WASH complex subunit 2C | chr10 | GO:0032271 | Not Cancer Driver | No | 90 | 0.068 | 1204 | 89 | 0.074 | 0 |