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Total number of protein in "GO:0032204" GO term:  78

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ACD_ENST00000620761 ACD Q96AP0 Adrenocortical dysplasia protein homolog chr16 GO:0032204 Not Cancer Driver No 49 0.107 256 34 0.133 1
ATM_ENST00000452508 ATM Q13315 Serine-protein kinase ATM chr11 GO:0032204 Census, Compendium Yes 469 0.153 225 39 0.173 41
ATR ATR Q13535 Serine/threonine-protein kinase ATR chr3 GO:0032204 Census, Compendium Yes 338 0.128 106 14 0.132 1
ATRX ATRX P46100 Transcriptional regulator ATRX chrX GO:0032204 Census, Compendium Yes 487 0.195 1672 301 0.18 33
AURKB_ENST00000585124 AURKB Q96GD4 Aurora kinase B chr17 GO:0032204 Not Cancer Driver No 51 0.148 63 8 0.127 0
CCT2 CCT2 P78371 T-complex protein 1 subunit beta chr12 GO:0032204 Not Cancer Driver No 63 0.118 46 3 0.065 0
CCT3 CCT3 P49368 T-complex protein 1 subunit gamma chr1 GO:0032204 Not Cancer Driver No 71 0.13 95 12 0.126 0
CCT4 CCT4 P50991 T-complex protein 1 subunit delta chr2 GO:0032204 Not Cancer Driver No 51 0.095 92 2 0.022 0
CCT5 CCT5 P48643 T-complex protein 1 subunit epsilon chr5 GO:0032204 Not Cancer Driver No 83 0.153 72 10 0.139 1
CCT6A CCT6A P40227 T-complex protein 1 subunit zeta chr7 GO:0032204 Not Cancer Driver No 66 0.124 5 1 0.2 0
CCT7 CCT7 Q99832 T-complex protein 1 subunit eta chr2 GO:0032204 Not Cancer Driver No 59 0.109 36 6 0.167 0
CCT8 CCT8 P50990 T-complex protein 1 subunit theta chr21 GO:0032204 Not Cancer Driver No 41 0.075 36 2 0.056 0
CTC1 CTC1 Q2NKJ3 CST complex subunit CTC1 chr17 GO:0032204 Not Cancer Driver No 142 0.117 103 8 0.078 9
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 GO:0032204 Census, Compendium Yes 415 0.531 288 301 1.045 14
DCP2 DCP2 Q8IU60 m7GpppN-mRNA hydrolase chr5 GO:0032204 Not Cancer Driver No 57 0.136 167 24 0.144 0
DHX36 DHX36 Q9H2U1 ATP-dependent DNA/RNA helicase DHX36 chr3 GO:0032204 Not Cancer Driver No 159 0.158 222 39 0.176 0
DKC1 DKC1 O60832 H/ACA ribonucleoprotein complex subunit DKC1 chrX GO:0032204 Not Cancer Driver No 62 0.121 145 29 0.2 24
ERCC1_ENST00000589165 ERCC1 P07992 DNA excision repair protein ERCC-1 chr19 GO:0032204 Not Cancer Driver No 42 0.141 105 14 0.133 1
ERCC4 ERCC4 Q92889 DNA repair endonuclease XPF chr16 GO:0032204 Census Yes 120 0.131 225 27 0.12 15
EXOSC10 EXOSC10 Q01780 Exosome component 10 chr1 GO:0032204 Not Cancer Driver No 87 0.098 375 35 0.093 0
FBXO4 FBXO4 Q9UKT5 F-box only protein 4 chr5 GO:0032204 Not Cancer Driver No 55 0.142 68 7 0.103 0
GNL3 GNL3 Q9BVP2 Guanine nucleotide-binding protein-like 3 chr3 GO:0032204 Not Cancer Driver No 56 0.102 257 21 0.082 0
GNL3L_ENST00000360845 GNL3L Q9NVN8 Guanine nucleotide-binding protein-like 3-like protein chrX GO:0032204 Not Cancer Driver No 120 0.206 242 43 0.178 0
HDAC8 HDAC8 Q9BY41 Histone deacetylase 8 chrX GO:0032204 Not Cancer Driver No 54 0.143 32 4 0.125 4
HMBOX1_ENST00000397358 HMBOX1 Q6NT76 Homeobox-containing protein 1 chr8 GO:0032204 Not Cancer Driver No 55 0.131 319 41 0.129 0
HNRNPA1 HNRNPA1 P09651 Heterogeneous nuclear ribonucleoprotein A1 chr12 GO:0032204 Not Cancer Driver No 70 0.188 290 58 0.2 4
HNRNPA2B1 HNRNPA2B1 P22626 Heterogeneous nuclear ribonucleoproteins A2/B1 chr7 GO:0032204 Census, Compendium Yes 68 0.193 255 41 0.161 0
HNRNPC_ENST00000420743 HNRNPC P07910 Heterogeneous nuclear ribonucleoproteins C1/C2 chr14 GO:0032204 Not Cancer Driver No 42 0.137 227 35 0.154 0
HNRNPD HNRNPD Q14103 Heterogeneous nuclear ribonucleoprotein D0 chr4 GO:0032204 Not Cancer Driver No 39 0.11 206 19 0.092 0
HNRNPU HNRNPU Q00839 Heterogeneous nuclear ribonucleoprotein U chr1 GO:0032204 Not Cancer Driver No 77 0.093 504 45 0.089 0
MAP2K7_ENST00000397979 MAP2K7 O14733 Dual specificity mitogen-activated protein kinase kinase 7 chr19 GO:0032204 Compendium Yes 89 0.212 144 20 0.139 0
MAP3K4 MAP3K4 Q9Y6R4 Mitogen-activated protein kinase kinase kinase 4 chr6 GO:0032204 Not Cancer Driver No 261 0.162 520 86 0.165 0
MAPK15 MAPK15 Q8TD08 Mitogen-activated protein kinase 15 chr8 GO:0032204 Not Cancer Driver No 81 0.149 235 37 0.157 0
MAPK1_ENST00000398822 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 GO:0032204 Census, Compendium Yes 62 0.172 2 0 0.0 7
MAPK3 MAPK3 P27361 Mitogen-activated protein kinase 3 chr16 GO:0032204 Not Cancer Driver No 38 0.1 49 5 0.102 0
MAPKAPK5 MAPKAPK5 Q8IW41 MAP kinase-activated protein kinase 5 chr12 GO:0032204 Not Cancer Driver No 51 0.108 101 12 0.119 0
MRE11 MRE11 P49959 Double-strand break repair protein MRE11 chr11 GO:0032204 Not Cancer Driver No 84 0.119 292 35 0.12 1
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 GO:0032204 Census, Compendium Yes 80 0.182 299 46 0.154 0
NABP2_ENST00000341463 NABP2 Q9BQ15 SOSS complex subunit B1 chr12 GO:0032204 Not Cancer Driver No 25 0.118 125 17 0.136 0
NAF1 NAF1 Q96HR8 H/ACA ribonucleoprotein complex non-core subunit NAF1 chr4 GO:0032204 Not Cancer Driver No 61 0.123 386 44 0.114 0
NAT10 NAT10 Q9H0A0 RNA cytidine acetyltransferase chr11 GO:0032204 Not Cancer Driver No 109 0.106 142 18 0.127 0
NBN NBN O60934 Nibrin chr8 GO:0032204 Census Yes 90 0.119 417 54 0.129 1
NEK2 NEK2 P51955 Serine/threonine-protein kinase Nek2 chr1 GO:0032204 Not Cancer Driver No 61 0.137 92 19 0.207 0
NEK7 NEK7 Q8TDX7 Serine/threonine-protein kinase Nek7 chr1 GO:0032204 Not Cancer Driver No 35 0.116 23 0 0.0 0
PARN PARN O95453 Poly(A)-specific ribonuclease PARN chr16 GO:0032204 Not Cancer Driver No 71 0.111 197 22 0.112 2
PARP1 PARP1 P09874 Poly [ADP-ribose] polymerase 1 chr1 GO:0032204 Not Cancer Driver No 119 0.117 320 34 0.106 0
PIF1_ENST00000559239 PIF1 Q9H611 ATP-dependent DNA helicase PIF1 chr15 GO:0032204 Not Cancer Driver No 54 0.084 209 11 0.053 0
PINX1 PINX1 Q96BK5 PIN2/TERF1-interacting telomerase inhibitor 1 chr8 GO:0032204 Not Cancer Driver No 66 0.201 328 66 0.201 0
PKIB_ENST00000368448 PKIB Q9C010 cAMP-dependent protein kinase inhibitor beta chr6 GO:0032204 Not Cancer Driver No 13 0.167 78 13 0.167 0
PML PML P29590 Protein PML chr15 GO:0032204 Census, Compendium Yes 112 0.127 312 34 0.109 0
PNKP PNKP Q96T60 Bifunctional polynucleotide phosphatase/kinase chr19 GO:0032204 Not Cancer Driver No 53 0.102 177 23 0.13 4
POT1 POT1 Q9NUX5 Protection of telomeres protein 1 chr7 GO:0032204 Census, Compendium Yes 113 0.178 31 6 0.194 9
PPP1R10 PPP1R10 Q96QC0 Serine/threonine-protein phosphatase 1 regulatory subunit 10 chr6 GO:0032204 Not Cancer Driver No 114 0.121 798 100 0.125 0
PRKCQ PRKCQ Q04759 Protein kinase C theta type chr10 GO:0032204 Not Cancer Driver No 147 0.208 28 9 0.321 0
RAD50 RAD50 Q92878 DNA repair protein RAD50 chr5 GO:0032204 Not Cancer Driver No 157 0.12 730 84 0.115 0
RTEL1_ENST00000370018 RTEL1 Q9NZ71 Regulator of telomere elongation helicase 1 chr20 GO:0032204 Not Cancer Driver No 144 0.118 474 64 0.135 14
SIRT6 SIRT6 Q8N6T7 NAD-dependent protein deacylase sirtuin-6 chr19 GO:0032204 Not Cancer Driver No 33 0.093 164 12 0.073 0
SLX1B SLX1B Q9BQ83 Structure-specific endonuclease subunit SLX1 chr16 GO:0032204 Not Cancer Driver No 3 0.011 80 1 0.013 0
SLX4 SLX4 Q8IY92 Structure-specific endonuclease subunit SLX4 chr16 GO:0032204 Not Cancer Driver No 271 0.148 1573 232 0.147 0
SMG1 SMG1 Q96Q15 Serine/threonine-protein kinase SMG1 chr16 GO:0032204 Not Cancer Driver No 348 0.095 605 73 0.121 0
SMG5 SMG5 Q9UPR3 Nonsense-mediated mRNA decay factor SMG5 chr1 GO:0032204 Not Cancer Driver No 132 0.13 295 51 0.173 0
SMG6 SMG6 Q86US8 Telomerase-binding protein EST1A chr17 GO:0032204 Not Cancer Driver No 166 0.117 751 97 0.129 0
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:0032204 Census Yes 53 0.099 130 11 0.085 1
STN1 STN1 Q9H668 CST complex subunit STN1 chr10 GO:0032204 Not Cancer Driver No 41 0.111 27 2 0.074 2
TCP1 TCP1 P17987 T-complex protein 1 subunit alpha chr6 GO:0032204 Not Cancer Driver No 54 0.097 55 10 0.182 0
TEN1 TEN1 Q86WV5 CST complex subunit TEN1 chr17 GO:0032204 Not Cancer Driver No 6 0.049 8 4 0.5 0
TERF1 TERF1 P54274 Telomeric repeat-binding factor 1 chr8 GO:0032204 Not Cancer Driver No 63 0.144 220 34 0.155 0
TERF2 TERF2 Q15554 Telomeric repeat-binding factor 2 chr16 GO:0032204 Not Cancer Driver No 33 0.061 361 20 0.055 0
TERF2IP TERF2IP Q9NYB0 Telomeric repeat-binding factor 2-interacting protein 1 chr16 GO:0032204 Not Cancer Driver No 28 0.07 310 16 0.052 0
TINF2 TINF2 Q9BSI4 TERF1-interacting nuclear factor 2 chr14 GO:0032204 Not Cancer Driver No 38 0.084 190 17 0.089 4
TNKS TNKS O95271 Poly [ADP-ribose] polymerase tankyrase-1 chr8 GO:0032204 Not Cancer Driver No 163 0.123 480 59 0.123 0
TNKS2 TNKS2 Q9H2K2 Poly [ADP-ribose] polymerase tankyrase-2 chr10 GO:0032204 Not Cancer Driver No 117 0.1 255 24 0.094 0
UPF1 UPF1 Q92900 Regulator of nonsense transcripts 1 chr19 GO:0032204 Not Cancer Driver No 146 0.129 329 36 0.109 0
USP7 USP7 Q93009 Ubiquitin carboxyl-terminal hydrolase 7 chr16 GO:0032204 Not Cancer Driver No 170 0.154 215 45 0.209 0
XRCC1 XRCC1 P18887 DNA repair protein XRCC1 chr19 GO:0032204 Not Cancer Driver No 85 0.134 426 53 0.124 1
XRCC5_ENST00000392132 XRCC5 P13010 X-ray repair cross-complementing protein 5 chr2 GO:0032204 Not Cancer Driver No 87 0.119 118 11 0.093 0
XRN1 XRN1 Q8IZH2 5'-3' exoribonuclease 1 chr3 GO:0032204 Not Cancer Driver No 213 0.125 577 65 0.113 0
YLPM1 YLPM1 P49750 YLP motif-containing protein 1 chr14 GO:0032204 Not Cancer Driver No 251 0.117 1985 226 0.114 0