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Total number of protein in "GO:0032147" GO term:  129

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0032147 Census, Compendium Yes 139 0.123 604 73 0.121 2
ACVR2B ACVR2B Q13705 Activin receptor type-2B chr3 GO:0032147 Not Cancer Driver No 83 0.162 70 14 0.2 2
ADCY8 ADCY8 P40145 Adenylate cyclase type 8 chr8 GO:0032147 Not Cancer Driver No 419 0.335 215 38 0.177 0
ADNP ADNP Q9H2P0 Activity-dependent neuroprotector homeobox protein chr20 GO:0032147 Not Cancer Driver No 130 0.118 615 66 0.107 0
ADRA2A ADRA2A P08913 Alpha-2A adrenergic receptor chr10 GO:0032147 Not Cancer Driver No 67 0.144 161 10 0.062 0
ADRA2B ADRA2B P18089 Alpha-2B adrenergic receptor chr2 GO:0032147 Not Cancer Driver No 73 0.162 136 20 0.147 0
ADRA2C ADRA2C P18825 Alpha-2C adrenergic receptor chr4 GO:0032147 Not Cancer Driver No 47 0.102 107 0 0.0 0
ADRB2 ADRB2 P07550 Beta-2 adrenergic receptor chr5 GO:0032147 Not Cancer Driver No 52 0.126 35 4 0.114 0
AGAP2 AGAP2 Q99490 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 chr12 GO:0032147 Not Cancer Driver No 133 0.112 754 81 0.107 0
ANG ANG P03950 Angiogenin chr14 GO:0032147 Not Cancer Driver No 19 0.129 36 2 0.056 14
ANGPT1 ANGPT1 Q15389 Angiopoietin-1 chr8 GO:0032147 Not Cancer Driver No 130 0.261 131 24 0.183 1
ANGPT4 ANGPT4 Q9Y264 Angiopoietin-4 chr20 GO:0032147 Not Cancer Driver No 104 0.207 150 32 0.213 0
AXIN1 AXIN1 O15169 Axin-1 chr16 GO:0032147 Census, Compendium Yes 120 0.139 619 88 0.142 4
CAB39 CAB39 Q9Y376 Calcium-binding protein 39 chr2 GO:0032147 Not Cancer Driver No 31 0.091 43 5 0.116 0
CAMKK2 CAMKK2 Q96RR4 Calcium/calmodulin-dependent protein kinase kinase 2 chr12 GO:0032147 Not Cancer Driver No 65 0.111 281 35 0.125 0
CARD10_ENST00000251973 CARD10 Q9BWT7 Caspase recruitment domain-containing protein 10 chr22 GO:0032147 Not Cancer Driver No 94 0.091 474 40 0.084 0
CARD14 CARD14 Q9BXL6 Caspase recruitment domain-containing protein 14 chr17 GO:0032147 Not Cancer Driver No 99 0.099 296 36 0.122 11
CCDC88A_ENST00000642200 CCDC88A Q3V6T2 Girdin chr2 GO:0032147 Not Cancer Driver No 226 0.121 1481 173 0.117 0
CD86 CD86 P42081 T-lymphocyte activation antigen CD86 chr3 GO:0032147 Not Cancer Driver No 90 0.274 56 18 0.321 0
CDK5R1 CDK5R1 Q15078 Cyclin-dependent kinase 5 activator 1 chr17 GO:0032147 Not Cancer Driver No 35 0.114 103 16 0.155 0
CDK5R2 CDK5R2 Q13319 Cyclin-dependent kinase 5 activator 2 chr2 GO:0032147 Not Cancer Driver No 14 0.038 204 5 0.025 0
CHI3L1 CHI3L1 P36222 Chitinase-3-like protein 1 chr1 GO:0032147 Not Cancer Driver No 66 0.172 24 5 0.208 0
CHRNA3 CHRNA3 P32297 Neuronal acetylcholine receptor subunit alpha-3 chr15 GO:0032147 Not Cancer Driver No 86 0.17 11 1 0.091 0
CLSPN CLSPN Q9HAW4 Claspin chr1 GO:0032147 Not Cancer Driver No 151 0.113 1283 147 0.115 0
COPS8 COPS8 Q99627 COP9 signalosome complex subunit 8 chr2 GO:0032147 Not Cancer Driver No 25 0.12 14 2 0.143 0
DAXX_ENST00000266000 DAXX Q9UER7 Death domain-associated protein 6 chr6 GO:0032147 Census, Compendium Yes 106 0.143 549 81 0.148 0
DBF4B DBF4B Q8NFT6 Protein DBF4 homolog B chr17 GO:0032147 Not Cancer Driver No 68 0.111 311 22 0.071 0
DGKQ DGKQ P52824 Diacylglycerol kinase theta chr4 GO:0032147 Not Cancer Driver No 56 0.059 264 11 0.042 0
DLG1_ENST00000419354 DLG1 Q12959 Disks large homolog 1 chr3 GO:0032147 Not Cancer Driver No 120 0.133 460 67 0.146 0
DRD2_ENST00000542968 DRD2 P14416 D(2) dopamine receptor chr11 GO:0032147 Not Cancer Driver No 127 0.287 124 45 0.363 0
DUSP19 DUSP19 Q8WTR2 Dual specificity protein phosphatase 19 chr2 GO:0032147 Not Cancer Driver No 34 0.157 15 5 0.333 0
DYNAP DYNAP Q8N1N2 Dynactin-associated protein chr18 GO:0032147 Not Cancer Driver No 54 0.257 78 21 0.269 0
ECT2 ECT2 Q9H8V3 Protein ECT2 chr3 GO:0032147 Not Cancer Driver No 104 0.114 284 33 0.116 0
EFNA5 EFNA5 P52803 Ephrin-A5 chr5 GO:0032147 Not Cancer Driver No 34 0.149 25 6 0.24 0
EGF EGF P01133 Pro-epidermal growth factor chr4 GO:0032147 Not Cancer Driver No 184 0.152 191 25 0.131 1
EMP2_ENST00000536829 EMP2 P54851 Epithelial membrane protein 2 chr16 GO:0032147 Not Cancer Driver No 24 0.144 0 0 0.0 2
EPO EPO P01588 Erythropoietin chr7 GO:0032147 Not Cancer Driver No 27 0.14 9 1 0.111 1
FGF13_ENST00000315930 FGF13 Q92913 Fibroblast growth factor 13 chrX GO:0032147 Not Cancer Driver No 70 0.286 96 33 0.344 2
FGF1_ENST00000612258 FGF1 P05230 Fibroblast growth factor 1 chr5 GO:0032147 Not Cancer Driver No 30 0.194 29 2 0.069 0
GAS6 GAS6 Q14393 Growth arrest-specific protein 6 chr13 GO:0032147 Not Cancer Driver No 82 0.121 42 6 0.143 0
GHR_ENST00000612382 GHR P10912 Growth hormone receptor chr5 GO:0032147 Not Cancer Driver No 173 0.271 229 66 0.288 19
GPRC5A GPRC5A Q8NFJ5 Retinoic acid-induced protein 3 chr12 GO:0032147 Not Cancer Driver No 43 0.12 19 4 0.211 0
GPRC5B_ENST00000569479 GPRC5B Q9NZH0 G-protein coupled receptor family C group 5 member B chr16 GO:0032147 Not Cancer Driver No 82 0.203 75 19 0.253 0
GPRC5C_ENST00000392629 GPRC5C Q9NQ84 G-protein coupled receptor family C group 5 member C chr17 GO:0032147 Not Cancer Driver No 77 0.175 58 15 0.259 0
GPRC5D GPRC5D Q9NZD1 G-protein coupled receptor family C group 5 member D chr12 GO:0032147 Not Cancer Driver No 32 0.093 32 1 0.031 0
GREM1 GREM1 O60565 Gremlin-1 chr15 GO:0032147 Not Cancer Driver No 25 0.136 77 12 0.156 0
IGF1_ENST00000307046 IGF1 P05019 Insulin-like growth factor I chr12 GO:0032147 Not Cancer Driver No 45 0.231 87 23 0.264 0
IL18 IL18 Q14116 Interleukin-18 chr11 GO:0032147 Not Cancer Driver No 19 0.098 16 3 0.188 0
IL4 IL4 P05112 Interleukin-4 chr5 GO:0032147 Not Cancer Driver No 18 0.118 0 0 0.0 0
INS INS P01308 Insulin chr11 GO:0032147 Not Cancer Driver No 15 0.136 5 1 0.2 22
INSR INSR P06213 Insulin receptor chr19 GO:0032147 Not Cancer Driver No 190 0.137 280 57 0.204 64
IRAK1 IRAK1 P51617 Interleukin-1 receptor-associated kinase 1 chrX GO:0032147 Compendium Yes 71 0.1 337 39 0.116 0
ITGB1BP1_ENST00000355346 ITGB1BP1 O14713 Integrin beta-1-binding protein 1 chr2 GO:0032147 Not Cancer Driver No 26 0.13 58 11 0.19 0
ITGB3 ITGB3 P05106 Integrin beta-3 chr17 GO:0032147 Not Cancer Driver No 124 0.157 66 5 0.076 30
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 GO:0032147 Census, Compendium Yes 136 0.12 59 5 0.085 5
KIF14 KIF14 Q15058 Kinesin-like protein KIF14 chr1 GO:0032147 Not Cancer Driver No 222 0.135 774 102 0.132 2
LEP LEP P41159 Leptin chr7 GO:0032147 Not Cancer Driver No 29 0.174 0 0 0.0 2
MADD MADD Q8WXG6 MAP kinase-activating death domain protein chr11 GO:0032147 Not Cancer Driver No 207 0.126 723 81 0.112 4
MALT1 MALT1 Q9UDY8 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 chr18 GO:0032147 Census, Compendium Yes 75 0.091 139 12 0.086 1
MAP2K1 MAP2K1 Q02750 Dual specificity mitogen-activated protein kinase kinase 1 chr15 GO:0032147 Census, Compendium Yes 94 0.239 96 24 0.25 6
MAP3K7 MAP3K7 O43318 Mitogen-activated protein kinase kinase kinase 7 chr6 GO:0032147 Not Cancer Driver No 104 0.172 333 66 0.198 6
MARK2 MARK2 Q7KZI7 Serine/threonine-protein kinase MARK2 chr11 GO:0032147 Compendium Yes 124 0.157 445 70 0.157 0
MAS1 MAS1 P04201 Proto-oncogene Mas chr6 GO:0032147 Not Cancer Driver No 47 0.145 5 2 0.4 0
MOB1A MOB1A Q9H8S9 MOB kinase activator 1A chr2 GO:0032147 Not Cancer Driver No 16 0.074 10 2 0.2 0
MOB1B_ENST00000309395 MOB1B Q7L9L4 MOB kinase activator 1B chr4 GO:0032147 Not Cancer Driver No 17 0.079 7 0 0.0 0
MOB2_ENST00000614710 MOB2 Q70IA6 MOB kinase activator 2 chr11 GO:0032147 Not Cancer Driver No 22 0.093 46 0 0.0 0
MOB3A MOB3A Q96BX8 MOB kinase activator 3A chr19 GO:0032147 Not Cancer Driver No 26 0.12 16 1 0.062 0
MOB3B MOB3B Q86TA1 MOB kinase activator 3B chr9 GO:0032147 Not Cancer Driver No 29 0.134 16 2 0.125 0
MOB3C_ENST00000371940 MOB3C Q70IA8 MOB kinase activator 3C chr1 GO:0032147 Not Cancer Driver No 38 0.176 1 0 0.0 0
MT3 MT3 P25713 Metallothionein-3 chr16 GO:0032147 Not Cancer Driver No 7 0.103 0 0 0.0 0
MTOR MTOR P42345 Serine/threonine-protein kinase mTOR chr1 GO:0032147 Census, Compendium Yes 379 0.149 296 37 0.125 18
NCKAP1L NCKAP1L P55160 Nck-associated protein 1-like chr12 GO:0032147 Not Cancer Driver No 247 0.219 51 10 0.196 4
NRG1_ENST00000405005 NRG1 Q02297 Pro-neuregulin-1, membrane-bound isoform chr8 GO:0032147 Census, Compendium Yes 159 0.248 528 132 0.25 0
NRG3_ENST00000404547 NRG3 P56975 Pro-neuregulin-3, membrane-bound isoform chr10 GO:0032147 Not Cancer Driver No 227 0.315 425 134 0.315 0
NTF3_ENST00000331010 NTF3 P20783 Neurotrophin-3 chr12 GO:0032147 Not Cancer Driver No 52 0.202 99 21 0.212 0
NTRK3_ENST00000629765 NTRK3 Q16288 NT-3 growth factor receptor chr15 GO:0032147 Census, Compendium Yes 249 0.297 57 21 0.368 0
OSBPL8 OSBPL8 Q9BZF1 Oxysterol-binding protein-related protein 8 chr12 GO:0032147 Not Cancer Driver No 105 0.118 401 37 0.092 0
PARK7_ENST00000377488 PARK7 Q99497 Parkinson disease protein 7 chr1 GO:0032147 Not Cancer Driver No 11 0.058 30 0 0.0 5
PDGFB PDGFB P01127 Platelet-derived growth factor subunit B chr22 GO:0032147 Census Yes 37 0.154 99 22 0.222 2
PDGFC PDGFC Q9NRA1 Platelet-derived growth factor C chr4 GO:0032147 Not Cancer Driver No 86 0.249 53 12 0.226 0
PDPK1 PDPK1 O15530 3-phosphoinositide-dependent protein kinase 1 chr16 GO:0032147 Not Cancer Driver No 33 0.059 121 12 0.099 0
PHB2 PHB2 Q99623 Prohibitin-2 chr12 GO:0032147 Not Cancer Driver No 31 0.104 26 4 0.154 0
PHB_ENST00000300408 PHB1 P35232 Prohibitin 1 chr17 GO:0032147 Not Cancer Driver No 37 0.136 4 1 0.25 0
PIBF1 PIBF1 Q8WXW3 Progesterone-induced-blocking factor 1 chr13 GO:0032147 Not Cancer Driver No 83 0.11 419 45 0.107 2
PIK3CA PIK3CA P42336 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform chr3 GO:0032147 Census, Compendium Yes 1669 1.563 38 11 0.289 30
PILRB PILRB Q9UKJ0 Paired immunoglobulin-like type 2 receptor beta chr7 GO:0032147 Not Cancer Driver No 29 0.128 26 3 0.115 0
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 GO:0032147 Not Cancer Driver No 57 0.098 99 13 0.131 23
PPIA PPIA P62937 Peptidyl-prolyl cis-trans isomerase A chr7 GO:0032147 Not Cancer Driver No 11 0.067 24 3 0.125 0
PPP2R3C PPP2R3C Q969Q6 Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma chr14 GO:0032147 Not Cancer Driver No 44 0.097 30 3 0.1 0
PRKAG2 PRKAG2 Q9UGJ0 5'-AMP-activated protein kinase subunit gamma-2 chr7 GO:0032147 Not Cancer Driver No 76 0.134 240 45 0.188 7
PRKCD_ENST00000330452 PRKCD Q05655 Protein kinase C delta type chr3 GO:0032147 Compendium Yes 79 0.117 43 9 0.209 0
PRKCZ PRKCZ Q05513 Protein kinase C zeta type chr1 GO:0032147 Not Cancer Driver No 70 0.118 116 11 0.095 0
PRLR PRLR P16471 Prolactin receptor chr5 GO:0032147 Not Cancer Driver No 154 0.248 282 70 0.248 2
PRNP PRNP P04156 Major prion protein chr20 GO:0032147 Not Cancer Driver No 36 0.142 115 7 0.061 18
PRRC1_ENST00000296666 PRRC1 Q96M27 Protein PRRC1 chr5 GO:0032147 Not Cancer Driver No 42 0.094 235 24 0.102 0
PTK2B_ENST00000346049 PTK2B Q14289 Protein-tyrosine kinase 2-beta chr8 GO:0032147 Not Cancer Driver No 161 0.16 261 37 0.142 0
RGCC RGCC Q9H4X1 Regulator of cell cycle RGCC chr13 GO:0032147 Not Cancer Driver No 9 0.066 81 7 0.086 0
RIPK3 RIPK3 Q9Y572 Receptor-interacting serine/threonine-protein kinase 3 chr14 GO:0032147 Not Cancer Driver No 66 0.127 295 39 0.132 0
RPLP1 RPLP1 P05386 60S acidic ribosomal protein P1 chr15 GO:0032147 Not Cancer Driver No 6 0.053 45 2 0.044 0
RPTOR RPTOR Q8N122 Regulatory-associated protein of mTOR chr17 GO:0032147 Not Cancer Driver No 176 0.132 241 21 0.087 0
SLC11A1 SLC11A1 P49279 Natural resistance-associated macrophage protein 1 chr2 GO:0032147 Not Cancer Driver No 79 0.144 47 5 0.106 0
SLC1A1 SLC1A1 P43005 Excitatory amino acid transporter 3 chr9 GO:0032147 Not Cancer Driver No 69 0.132 17 4 0.235 1
SPDYA_ENST00000379579 SPDYA Q5MJ70 Speedy protein A chr2 GO:0032147 Not Cancer Driver No 39 0.125 119 11 0.092 0
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:0032147 Census Yes 53 0.099 130 11 0.085 1
STK11 STK11 Q15831 Serine/threonine-protein kinase STK11 chr19 GO:0032147 Census, Compendium Yes 75 0.173 135 14 0.104 9
STRADA STRADA Q7RTN6 STE20-related kinase adapter protein alpha chr17 GO:0032147 Not Cancer Driver No 49 0.114 118 14 0.119 0
STRADB STRADB Q9C0K7 STE20-related kinase adapter protein beta chr2 GO:0032147 Not Cancer Driver No 53 0.127 84 7 0.083 0
TAL1 TAL1 P17542 T-cell acute lymphocytic leukemia protein 1 chr1 GO:0032147 Census Yes 54 0.163 305 53 0.174 0
TAOK2 TAOK2 Q9UL54 Serine/threonine-protein kinase TAO2 chr16 GO:0032147 Not Cancer Driver No 191 0.155 666 102 0.153 0
TGFB2_ENST00000366930 TGFB2 P61812 Transforming growth factor beta-2 proprotein chr1 GO:0032147 Not Cancer Driver No 63 0.152 47 8 0.17 3
TGFBR2_ENST00000295754 TGFBR2 P37173 TGF-beta receptor type-2 chr3 GO:0032147 Census, Compendium Yes 106 0.187 60 16 0.267 25
TIRAP_ENST00000392680 TIRAP P58753 Toll/interleukin-1 receptor domain-containing adapter protein chr11 GO:0032147 Not Cancer Driver No 28 0.127 80 6 0.075 0
TLR3 TLR3 O15455 Toll-like receptor 3 chr4 GO:0032147 Not Cancer Driver No 123 0.136 0 0 0.0 1
TLR6 TLR6 Q9Y2C9 Toll-like receptor 6 chr4 GO:0032147 Not Cancer Driver No 99 0.124 1 0 0.0 0
TNFRSF10A TNFRSF10A O00220 Tumor necrosis factor receptor superfamily member 10A chr8 GO:0032147 Not Cancer Driver No 55 0.118 174 17 0.098 0
TNFRSF10B TNFRSF10B O14763 Tumor necrosis factor receptor superfamily member 10B chr8 GO:0032147 Not Cancer Driver No 44 0.1 190 19 0.1 0
TNFSF15 TNFSF15 O95150 Tumor necrosis factor ligand superfamily member 15 chr9 GO:0032147 Not Cancer Driver No 41 0.163 49 12 0.245 0
TOM1L1 TOM1L1 O75674 TOM1-like protein 1 chr17 GO:0032147 Not Cancer Driver No 51 0.107 268 29 0.108 0
TPX2 TPX2 Q9ULW0 Targeting protein for Xklp2 chr20 GO:0032147 Not Cancer Driver No 92 0.123 695 86 0.124 0
TRAF2 TRAF2 Q12933 TNF receptor-associated factor 2 chr9 GO:0032147 Not Cancer Driver No 63 0.126 4 1 0.25 0
TRAF4 TRAF4 Q9BUZ4 TNF receptor-associated factor 4 chr17 GO:0032147 Not Cancer Driver No 42 0.089 27 1 0.037 0
TRAF6_ENST00000348124 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 GO:0032147 Not Cancer Driver No 67 0.128 62 7 0.113 0
TXN TXN P10599 Thioredoxin chr9 GO:0032147 Not Cancer Driver No 6 0.057 0 0 0.0 0
UCN UCN P55089 Urocortin chr2 GO:0032147 Not Cancer Driver No 7 0.056 61 4 0.066 0
VEGFA_ENST00000523873 VEGFA P15692 Vascular endothelial growth factor A chr6 GO:0032147 Not Cancer Driver No 27 0.116 41 7 0.171 0
WNK1_ENST00000315939 WNK1 Q9H4A3 Serine/threonine-protein kinase WNK1 chr12 GO:0032147 Not Cancer Driver No 278 0.117 1959 223 0.114 0
WNT11 WNT11 O96014 Protein Wnt-11 chr11 GO:0032147 Not Cancer Driver No 55 0.155 59 4 0.068 0
WNT5A_ENST00000474267 WNT5A P41221 Protein Wnt-5a chr3 GO:0032147 Not Cancer Driver No 66 0.174 0 0 0.0 2
ZFP91 ZFP91 Q96JP5 E3 ubiquitin-protein ligase ZFP91 chr11 GO:0032147 Not Cancer Driver No 85 0.149 383 55 0.144 0