Total number of protein in "GO:0032088" GO term: 86
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACOD1 | ACOD1 | A6NK06 | Cis-aconitate decarboxylase | chr13 | GO:0032088 | Not Cancer Driver | No | 5 | 0.01 | 36 | 0 | 0.0 | 0 |
| ADORA3 | ADORA3 | P0DMS8 | Adenosine receptor A3 | chr1 | GO:0032088 | Not Cancer Driver | No | 45 | 0.142 | 4 | 1 | 0.25 | 0 |
| AIM2 | AIM2 | O14862 | Interferon-inducible protein AIM2 | chr1 | GO:0032088 | Not Cancer Driver | No | 73 | 0.213 | 78 | 22 | 0.282 | 0 |
| ANXA4 | ANXA4 | P09525 | Annexin A4 | chr2 | GO:0032088 | Not Cancer Driver | No | 47 | 0.147 | 41 | 6 | 0.146 | 0 |
| ARRB1 | ARRB1 | P49407 | Beta-arrestin-1 | chr11 | GO:0032088 | Not Cancer Driver | No | 49 | 0.117 | 154 | 13 | 0.084 | 0 |
| ARRB2_ENST00000269260 | ARRB2 | P32121 | Beta-arrestin-2 | chr17 | GO:0032088 | Not Cancer Driver | No | 46 | 0.112 | 122 | 22 | 0.18 | 0 |
| BCL3 | BCL3 | P20749 | B-cell lymphoma 3 protein | chr19 | GO:0032088 | Census | Yes | 44 | 0.097 | 259 | 23 | 0.089 | 0 |
| BMP7 | BMP7 | P18075 | Bone morphogenetic protein 7 | chr20 | GO:0032088 | Not Cancer Driver | No | 91 | 0.211 | 69 | 18 | 0.261 | 0 |
| BRMS1_ENST00000359957 | BRMS1 | Q9HCU9 | Breast cancer metastasis-suppressor 1 | chr11 | GO:0032088 | Not Cancer Driver | No | 42 | 0.171 | 115 | 18 | 0.157 | 0 |
| CACTIN | CACTIN | Q8WUQ7 | Cactin | chr19 | GO:0032088 | Not Cancer Driver | No | 94 | 0.124 | 503 | 54 | 0.107 | 0 |
| CARD8_ENST00000519940 | CARD8 | Q9Y2G2 | Caspase recruitment domain-containing protein 8 | chr19 | GO:0032088 | Not Cancer Driver | No | 53 | 0.099 | 126 | 7 | 0.056 | 1 |
| CAT | CAT | P04040 | Catalase | chr11 | GO:0032088 | Not Cancer Driver | No | 70 | 0.133 | 176 | 18 | 0.102 | 0 |
| CCDC22 | CCDC22 | O60826 | Coiled-coil domain-containing protein 22 | chrX | GO:0032088 | Not Cancer Driver | No | 62 | 0.099 | 243 | 18 | 0.074 | 2 |
| CD200_ENST00000315711 | CD200 | P41217 | OX-2 membrane glycoprotein | chr3 | GO:0032088 | Not Cancer Driver | No | 37 | 0.133 | 14 | 0 | 0.0 | 0 |
| CDK5RAP3_ENST00000338399 | CDK5RAP3 | Q96JB5 | CDK5 regulatory subunit-associated protein 3 | chr17 | GO:0032088 | Not Cancer Driver | No | 50 | 0.099 | 99 | 20 | 0.202 | 0 |
| CDKN2A_ENST00000304494 | CDKN2A | P42771 | Cyclin-dependent kinase inhibitor 2A | chr9 | GO:0032088 | Census, Compendium | Yes | 166 | 1.064 | 83 | 88 | 1.06 | 36 |
| CHP1 | CHP1 | Q99653 | Calcineurin B homologous protein 1 | chr15 | GO:0032088 | Not Cancer Driver | No | 27 | 0.138 | 70 | 12 | 0.171 | 0 |
| CHUK | CHUK | O15111 | Inhibitor of nuclear factor kappa-B kinase subunit alpha | chr10 | GO:0032088 | Not Cancer Driver | No | 74 | 0.099 | 116 | 9 | 0.078 | 0 |
| CMKLR1 | CMKLR1 | Q99788 | Chemerin-like receptor 1 | chr12 | GO:0032088 | Not Cancer Driver | No | 107 | 0.287 | 24 | 13 | 0.542 | 0 |
| COMMD1 | COMMD1 | Q8N668 | COMM domain-containing protein 1 | chr2 | GO:0032088 | Not Cancer Driver | No | 21 | 0.111 | 17 | 0 | 0.0 | 0 |
| COMMD6_ENST00000377615 | COMMD6 | Q7Z4G1 | COMM domain-containing protein 6 | chr13 | GO:0032088 | Not Cancer Driver | No | 11 | 0.129 | 12 | 2 | 0.167 | 0 |
| COMMD7 | COMMD7 | Q86VX2 | COMM domain-containing protein 7 | chr20 | GO:0032088 | Not Cancer Driver | No | 29 | 0.145 | 21 | 0 | 0.0 | 0 |
| CYLD | CYLD | Q9NQC7 | Ubiquitin carboxyl-terminal hydrolase CYLD | chr16 | GO:0032088 | Census, Compendium | Yes | 116 | 0.121 | 213 | 31 | 0.146 | 3 |
| CYP1B1 | CYP1B1 | Q16678 | Cytochrome P450 1B1 | chr2 | GO:0032088 | Not Cancer Driver | No | 61 | 0.112 | 31 | 3 | 0.097 | 40 |
| DAB2IP_ENST00000408936 | DAB2IP | Q5VWQ8 | Disabled homolog 2-interacting protein | chr9 | GO:0032088 | Not Cancer Driver | No | 131 | 0.11 | 681 | 68 | 0.1 | 0 |
| DAP_ENST00000230895 | DAP | P51397 | Death-associated protein 1 | chr5 | GO:0032088 | Not Cancer Driver | No | 10 | 0.098 | 102 | 10 | 0.098 | 0 |
| DDIT3_ENST00000623876 | DDIT3 | P35638 | DNA damage-inducible transcript 3 protein | chr12 | GO:0032088 | Census | Yes | 29 | 0.172 | 160 | 27 | 0.169 | 0 |
| ERBIN_ENST00000284037 | ERBIN | Q96RT1 | Erbin | chr5 | GO:0032088 | Not Cancer Driver | No | 167 | 0.118 | 967 | 118 | 0.122 | 0 |
| FAF1 | FAF1 | Q9UNN5 | FAS-associated factor 1 | chr1 | GO:0032088 | Not Cancer Driver | No | 83 | 0.128 | 241 | 34 | 0.141 | 0 |
| FOXJ1 | FOXJ1 | Q92949 | Forkhead box protein J1 | chr17 | GO:0032088 | Not Cancer Driver | No | 25 | 0.059 | 279 | 18 | 0.065 | 0 |
| FOXP3 | FOXP3 | Q9BZS1 | Forkhead box protein P3 | chrX | GO:0032088 | Not Cancer Driver | No | 38 | 0.088 | 186 | 16 | 0.086 | 10 |
| G3BP2_ENST00000395719 | G3BP2 | Q9UN86 | Ras GTPase-activating protein-binding protein 2 | chr4 | GO:0032088 | Not Cancer Driver | No | 64 | 0.133 | 384 | 53 | 0.138 | 0 |
| GFI1 | GFI1 | Q99684 | Zinc finger protein Gfi-1 | chr1 | GO:0032088 | Not Cancer Driver | No | 57 | 0.135 | 199 | 29 | 0.146 | 2 |
| HAVCR2 | HAVCR2 | Q8TDQ0 | Hepatitis A virus cellular receptor 2 | chr5 | GO:0032088 | Not Cancer Driver | No | 69 | 0.229 | 17 | 2 | 0.118 | 3 |
| IL10 | IL10 | P22301 | Interleukin-10 | chr1 | GO:0032088 | Not Cancer Driver | No | 19 | 0.107 | 23 | 1 | 0.043 | 0 |
| IRAK1 | IRAK1 | P51617 | Interleukin-1 receptor-associated kinase 1 | chrX | GO:0032088 | Compendium | Yes | 71 | 0.1 | 337 | 39 | 0.116 | 0 |
| IRAK2 | IRAK2 | O43187 | Interleukin-1 receptor-associated kinase-like 2 | chr3 | GO:0032088 | Not Cancer Driver | No | 84 | 0.134 | 202 | 32 | 0.158 | 0 |
| IRAK3 | IRAK3 | Q9Y616 | Interleukin-1 receptor-associated kinase 3 | chr12 | GO:0032088 | Not Cancer Driver | No | 103 | 0.173 | 79 | 14 | 0.177 | 0 |
| ITCH | ITCH | Q96J02 | E3 ubiquitin-protein ligase Itchy homolog | chr20 | GO:0032088 | Not Cancer Driver | No | 95 | 0.105 | 335 | 42 | 0.125 | 0 |
| LRRC14 | LRRC14 | Q15048 | Leucine-rich repeat-containing protein 14 | chr8 | GO:0032088 | Not Cancer Driver | No | 63 | 0.128 | 25 | 2 | 0.08 | 0 |
| MAP2K5 | MAP2K5 | Q13163 | Dual specificity mitogen-activated protein kinase kinase 5 | chr15 | GO:0032088 | Not Cancer Driver | No | 40 | 0.089 | 85 | 10 | 0.118 | 0 |
| MTURN | MTURN | Q8N3F0 | Maturin | chr7 | GO:0032088 | Not Cancer Driver | No | 15 | 0.115 | 27 | 6 | 0.222 | 0 |
| NFKBIA | NFKBIA | P25963 | NF-kappa-B inhibitor alpha | chr14 | GO:0032088 | Compendium | Yes | 37 | 0.117 | 102 | 9 | 0.088 | 1 |
| NFKBIB | NFKBIB | Q15653 | NF-kappa-B inhibitor beta | chr19 | GO:0032088 | Not Cancer Driver | No | 42 | 0.118 | 223 | 29 | 0.13 | 0 |
| NFKBIL1 | NFKBIL1 | Q9UBC1 | NF-kappa-B inhibitor-like protein 1 | chr6 | GO:0032088 | Not Cancer Driver | No | 37 | 0.097 | 316 | 33 | 0.104 | 0 |
| NLRC3 | NLRC3 | Q7RTR2 | NLR family CARD domain-containing protein 3 | chr16 | GO:0032088 | Not Cancer Driver | No | 176 | 0.165 | 147 | 33 | 0.224 | 0 |
| NLRC5_ENST00000436936 | NLRC5 | Q86WI3 | Protein NLRC5 | chr16 | GO:0032088 | Not Cancer Driver | No | 262 | 0.14 | 114 | 19 | 0.167 | 0 |
| NLRP12_ENST00000324134 | NLRP12 | P59046 | NACHT, LRR and PYD domains-containing protein 12 | chr19 | GO:0032088 | Not Cancer Driver | No | 310 | 0.292 | 116 | 43 | 0.371 | 0 |
| NLRP2 | NLRP2 | Q9NX02 | NACHT, LRR and PYD domains-containing protein 2 | chr19 | GO:0032088 | Not Cancer Driver | No | 257 | 0.242 | 60 | 15 | 0.25 | 0 |
| NLRP3_ENST00000391828 | NLRP3 | Q96P20 | NACHT, LRR and PYD domains-containing protein 3 | chr1 | GO:0032088 | Not Cancer Driver | No | 339 | 0.327 | 64 | 33 | 0.516 | 37 |
| NOD2 | NOD2 | Q9HC29 | Nucleotide-binding oligomerization domain-containing protein 2 | chr16 | GO:0032088 | Not Cancer Driver | No | 169 | 0.163 | 40 | 4 | 0.1 | 15 |
| NR1H4 | NR1H4 | Q96RI1 | Bile acid receptor | chr12 | GO:0032088 | Not Cancer Driver | No | 111 | 0.228 | 78 | 18 | 0.231 | 0 |
| NWD1_ENST00000552788 | NWD1 | Q149M9 | NACHT domain- and WD repeat-containing protein 1 | chr19 | GO:0032088 | Not Cancer Driver | No | 323 | 0.207 | 87 | 15 | 0.172 | 0 |
| OTULIN | OTULIN | Q96BN8 | Ubiquitin thioesterase otulin | chr5 | GO:0032088 | Not Cancer Driver | No | 47 | 0.134 | 97 | 5 | 0.052 | 2 |
| PARP10_ENST00000313028 | PARP10 | Q53GL7 | Protein mono-ADP-ribosyltransferase PARP10 | chr8 | GO:0032088 | Not Cancer Driver | No | 122 | 0.119 | 552 | 68 | 0.123 | 0 |
| PELI1 | PELI1 | Q96FA3 | E3 ubiquitin-protein ligase pellino homolog 1 | chr2 | GO:0032088 | Not Cancer Driver | No | 47 | 0.112 | 167 | 17 | 0.102 | 0 |
| PIAS4 | PIAS4 | Q8N2W9 | E3 SUMO-protein ligase PIAS4 | chr19 | GO:0032088 | Not Cancer Driver | No | 58 | 0.114 | 142 | 23 | 0.162 | 0 |
| PKHD1 | PKHD1 | P08F94 | Fibrocystin | chr6 | GO:0032088 | Not Cancer Driver | No | 778 | 0.191 | 413 | 81 | 0.196 | 93 |
| PPP2CB | PPP2CB | P62714 | Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform | chr8 | GO:0032088 | Not Cancer Driver | No | 37 | 0.12 | 12 | 0 | 0.0 | 0 |
| PRDX2 | PRDX2 | P32119 | Peroxiredoxin-2 | chr19 | GO:0032088 | Not Cancer Driver | No | 24 | 0.121 | 30 | 4 | 0.133 | 0 |
| PRMT2_ENST00000355680 | PRMT2 | P55345 | Protein arginine N-methyltransferase 2 | chr21 | GO:0032088 | Not Cancer Driver | No | 48 | 0.111 | 70 | 8 | 0.114 | 0 |
| PSMD10 | PSMD10 | O75832 | 26S proteasome non-ATPase regulatory subunit 10 | chrX | GO:0032088 | Not Cancer Driver | No | 20 | 0.088 | 53 | 5 | 0.094 | 0 |
| PTGIS | PTGIS | Q16647 | Prostacyclin synthase | chr20 | GO:0032088 | Not Cancer Driver | No | 102 | 0.204 | 18 | 3 | 0.167 | 0 |
| PYCARD | PYCARD | Q9ULZ3 | Apoptosis-associated speck-like protein containing a CARD | chr16 | GO:0032088 | Not Cancer Driver | No | 16 | 0.082 | 39 | 4 | 0.103 | 0 |
| PYDC1 | PYDC1 | Q8WXC3 | Pyrin domain-containing protein 1 | chr16 | GO:0032088 | Not Cancer Driver | No | 28 | 0.315 | 0 | 0 | 0.0 | 0 |
| PYDC2 | PYDC2 | Q56P42 | Pyrin domain-containing protein 2 | chr3 | GO:0032088 | Not Cancer Driver | No | 20 | 0.206 | 26 | 5 | 0.192 | 0 |
| RBCK1 | RBCK1 | Q9BYM8 | RanBP-type and C3HC4-type zinc finger-containing protein 1 | chr20 | GO:0032088 | Not Cancer Driver | No | 52 | 0.102 | 140 | 14 | 0.1 | 2 |
| RWDD3 | RWDD3 | Q9Y3V2 | RWD domain-containing protein 3 | chr1 | GO:0032088 | Not Cancer Driver | No | 40 | 0.15 | 12 | 4 | 0.333 | 0 |
| SETD6 | SETD6 | Q8TBK2 | N-lysine methyltransferase SETD6 | chr16 | GO:0032088 | Not Cancer Driver | No | 42 | 0.089 | 105 | 9 | 0.086 | 0 |
| SIRT1 | SIRT1 | Q96EB6 | NAD-dependent protein deacetylase sirtuin-1 | chr10 | GO:0032088 | Not Cancer Driver | No | 70 | 0.094 | 435 | 31 | 0.071 | 0 |
| SPI1_ENST00000378538 | SPI1 | P17947 | Transcription factor PU.1 | chr11 | GO:0032088 | Not Cancer Driver | No | 46 | 0.17 | 187 | 34 | 0.182 | 0 |
| TAX1BP1 | TAX1BP1 | Q86VP1 | Tax1-binding protein 1 | chr7 | GO:0032088 | Not Cancer Driver | No | 78 | 0.099 | 429 | 50 | 0.117 | 0 |
| TCEAL7 | TCEAL7 | Q9BRU2 | Transcription elongation factor A protein-like 7 | chrX | GO:0032088 | Not Cancer Driver | No | 14 | 0.14 | 92 | 12 | 0.13 | 0 |
| TLR9 | TLR9 | Q9NR96 | Toll-like receptor 9 | chr3 | GO:0032088 | Not Cancer Driver | No | 141 | 0.137 | 35 | 3 | 0.086 | 0 |
| TMIGD3_ENST00000369717 | TMIGD3 | P0DMS9 | Transmembrane domain-containing protein TMIGD3 | chr1 | GO:0032088 | Not Cancer Driver | No | 49 | 0.184 | 57 | 10 | 0.175 | 0 |
| TMSB4X_ENST00000380633 | TMSB4X | P62328 | Thymosin beta-4 | chrX | GO:0032088 | Census | Yes | 7 | 0.159 | 44 | 7 | 0.159 | 0 |
| TNFAIP3 | TNFAIP3 | P21580 | Tumor necrosis factor alpha-induced protein 3 | chr6 | GO:0032088 | Census, Compendium | Yes | 98 | 0.124 | 231 | 33 | 0.143 | 1 |
| TRAF3_ENST00000392745 | TRAF3 | Q13114 | TNF receptor-associated factor 3 | chr14 | GO:0032088 | Compendium | Yes | 61 | 0.107 | 101 | 9 | 0.089 | 1 |
| TRAIP | TRAIP | Q9BWF2 | E3 ubiquitin-protein ligase TRAIP | chr3 | GO:0032088 | Not Cancer Driver | No | 63 | 0.134 | 240 | 33 | 0.138 | 1 |
| TRIM21 | TRIM21 | P19474 | E3 ubiquitin-protein ligase TRIM21 | chr11 | GO:0032088 | Not Cancer Driver | No | 85 | 0.179 | 49 | 7 | 0.143 | 0 |
| TRIM37 | TRIM37 | O94972 | E3 ubiquitin-protein ligase TRIM37 | chr17 | GO:0032088 | Not Cancer Driver | No | 119 | 0.123 | 492 | 60 | 0.122 | 3 |
| TRIM40_ENST00000376724 | TRIM40 | Q6P9F5 | E3 ubiquitin ligase TRIM40 | chr6 | GO:0032088 | Not Cancer Driver | No | 44 | 0.171 | 84 | 12 | 0.143 | 0 |
| UFL1 | UFL1 | O94874 | E3 UFM1-protein ligase 1 | chr6 | GO:0032088 | Not Cancer Driver | No | 109 | 0.137 | 141 | 24 | 0.17 | 0 |
| USP7 | USP7 | Q93009 | Ubiquitin carboxyl-terminal hydrolase 7 | chr16 | GO:0032088 | Not Cancer Driver | No | 170 | 0.154 | 215 | 45 | 0.209 | 0 |
| ZC3H12A | ZC3H12A | Q5D1E8 | Endoribonuclease ZC3H12A | chr1 | GO:0032088 | Not Cancer Driver | No | 90 | 0.15 | 396 | 44 | 0.111 | 0 |
| ZNF675 | ZNF675 | Q8TD23 | Zinc finger protein 675 | chr19 | GO:0032088 | Not Cancer Driver | No | 114 | 0.201 | 91 | 19 | 0.209 | 0 |