Total number of protein in "GO:0032007" GO term: 42
Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
AC006486.1 | AC006486.1 | M0QYV0 | Protein kinase domain-containing protein (Fragment) | chr19 | GO:0032007 | Not Cancer Driver | No | 23 | 0.138 | 21 | 1 | 0.048 | 0 |
AKT1S1_ENST00000391834 | AKT1S1 | Q96B36 | Proline-rich AKT1 substrate 1 | chr19 | GO:0032007 | Not Cancer Driver | No | 23 | 0.09 | 256 | 23 | 0.09 | 0 |
ARNTL | ARNTL | O00327 | Aryl hydrocarbon receptor nuclear translocator-like protein 1 | chr11 | GO:0032007 | Not Cancer Driver | No | 71 | 0.113 | 332 | 40 | 0.12 | 0 |
ATM_ENST00000452508 | ATM | Q13315 | Serine-protein kinase ATM | chr11 | GO:0032007 | Census, Compendium | Yes | 469 | 0.153 | 225 | 39 | 0.173 | 41 |
BMT2 | BMT2 | Q1RMZ1 | S-adenosylmethionine sensor upstream of mTORC1 | chr7 | GO:0032007 | Not Cancer Driver | No | 65 | 0.16 | 81 | 10 | 0.123 | 0 |
C12orf66_ENST00000398055 | KICS2 | Q96MD2 | KICSTOR subunit 2 | chr12 | GO:0032007 | Not Cancer Driver | No | 61 | 0.137 | 35 | 6 | 0.171 | 0 |
CASTOR1 | CASTOR1 | Q8WTX7 | Cytosolic arginine sensor for mTORC1 subunit 1 | chr22 | GO:0032007 | Not Cancer Driver | No | 27 | 0.082 | 39 | 5 | 0.128 | 0 |
CASTOR3 | CASTOR3 | Q8NAP1 | Putative protein CASTOR 3 | chr7 | GO:0032007 | Not Cancer Driver | No | 18 | 0.11 | 1 | 0 | 0.0 | 0 |
CRYBA1 | CRYBA1 | P05813 | Beta-crystallin A3 | chr17 | GO:0032007 | Not Cancer Driver | No | 29 | 0.135 | 52 | 11 | 0.212 | 0 |
DDIT4 | DDIT4 | Q9NX09 | DNA damage-inducible transcript 4 protein | chr10 | GO:0032007 | Not Cancer Driver | No | 20 | 0.086 | 87 | 9 | 0.103 | 0 |
DEPDC5_ENST00000382112 | DEPDC5 | O75140 | GATOR complex protein DEPDC5 | chr22 | GO:0032007 | Not Cancer Driver | No | 226 | 0.141 | 575 | 91 | 0.158 | 7 |
DEPTOR | DEPTOR | Q8TB45 | DEP domain-containing mTOR-interacting protein | chr8 | GO:0032007 | Not Cancer Driver | No | 57 | 0.139 | 125 | 12 | 0.096 | 0 |
ENDOG | ENDOG | Q14249 | Endonuclease G, mitochondrial | chr9 | GO:0032007 | Not Cancer Driver | No | 11 | 0.037 | 61 | 1 | 0.016 | 0 |
FLCN | FLCN | Q8NFG4 | Folliculin | chr17 | GO:0032007 | Census, Compendium | Yes | 59 | 0.102 | 157 | 19 | 0.121 | 5 |
FNIP1 | FNIP1 | Q8TF40 | Folliculin-interacting protein 1 | chr5 | GO:0032007 | Not Cancer Driver | No | 143 | 0.123 | 384 | 44 | 0.115 | 0 |
GSK3A | GSK3A | P49840 | Glycogen synthase kinase-3 alpha | chr19 | GO:0032007 | Not Cancer Driver | No | 55 | 0.114 | 180 | 8 | 0.044 | 0 |
HIF1A_ENST00000337138 | HIF1A | Q16665 | Hypoxia-inducible factor 1-alpha | chr14 | GO:0032007 | Census | Yes | 118 | 0.143 | 435 | 51 | 0.117 | 0 |
ITFG2 | ITFG2 | Q969R8 | KICSTOR complex protein ITFG2 | chr12 | GO:0032007 | Not Cancer Driver | No | 59 | 0.132 | 61 | 9 | 0.148 | 0 |
KPTN | KPTN | Q9Y664 | KICSTOR complex protein kaptin | chr19 | GO:0032007 | Not Cancer Driver | No | 44 | 0.101 | 21 | 2 | 0.095 | 0 |
MAPKAPK5 | MAPKAPK5 | Q8IW41 | MAP kinase-activated protein kinase 5 | chr12 | GO:0032007 | Not Cancer Driver | No | 51 | 0.108 | 101 | 12 | 0.119 | 0 |
MINAR1 | MINAR1 | Q9UPX6 | Major intrinsically disordered Notch2-binding receptor 1 | chr15 | GO:0032007 | Not Cancer Driver | No | 171 | 0.187 | 584 | 104 | 0.178 | 0 |
MTM1 | MTM1 | Q13496 | Myotubularin | chrX | GO:0032007 | Not Cancer Driver | No | 112 | 0.186 | 79 | 9 | 0.114 | 57 |
NPRL2 | NPRL2 | Q8WTW4 | GATOR complex protein NPRL2 | chr3 | GO:0032007 | Compendium | Yes | 37 | 0.097 | 10 | 3 | 0.3 | 1 |
NPRL3_ENST00000611875 | NPRL3 | Q12980 | GATOR complex protein NPRL3 | chr16 | GO:0032007 | Not Cancer Driver | No | 45 | 0.079 | 158 | 22 | 0.139 | 0 |
PDCD6 | PDCD6 | O75340 | Programmed cell death protein 6 | chr5 | GO:0032007 | Not Cancer Driver | No | 21 | 0.11 | 24 | 1 | 0.042 | 0 |
PRKAA1_ENST00000397128 | PRKAA1 | Q13131 | 5'-AMP-activated protein kinase catalytic subunit alpha-1 | chr5 | GO:0032007 | Not Cancer Driver | No | 72 | 0.129 | 124 | 17 | 0.137 | 0 |
PRKAA2 | PRKAA2 | P54646 | 5'-AMP-activated protein kinase catalytic subunit alpha-2 | chr1 | GO:0032007 | Not Cancer Driver | No | 128 | 0.232 | 98 | 26 | 0.265 | 0 |
RNF152 | RNF152 | Q8N8N0 | E3 ubiquitin-protein ligase RNF152 | chr18 | GO:0032007 | Not Cancer Driver | No | 61 | 0.3 | 34 | 11 | 0.324 | 0 |
SESN1_ENST00000356644 | SESN1 | Q9Y6P5 | Sestrin-1 | chr6 | GO:0032007 | Not Cancer Driver | No | 45 | 0.091 | 48 | 4 | 0.083 | 0 |
SESN2 | SESN2 | P58004 | Sestrin-2 | chr1 | GO:0032007 | Not Cancer Driver | No | 74 | 0.154 | 147 | 26 | 0.177 | 0 |
SESN3 | SESN3 | P58005 | Sestrin-3 | chr11 | GO:0032007 | Not Cancer Driver | No | 84 | 0.171 | 44 | 4 | 0.091 | 0 |
SH3BP4_ENST00000392011 | SH3BP4 | Q9P0V3 | SH3 domain-binding protein 4 | chr2 | GO:0032007 | Not Cancer Driver | No | 143 | 0.148 | 241 | 43 | 0.178 | 0 |
SIRT1 | SIRT1 | Q96EB6 | NAD-dependent protein deacetylase sirtuin-1 | chr10 | GO:0032007 | Not Cancer Driver | No | 70 | 0.094 | 435 | 31 | 0.071 | 0 |
STK11 | STK11 | Q15831 | Serine/threonine-protein kinase STK11 | chr19 | GO:0032007 | Census, Compendium | Yes | 75 | 0.173 | 135 | 14 | 0.104 | 9 |
SZT2_ENST00000634258 | SZT2 | Q5T011 | KICSTOR complex protein SZT2 | chr1 | GO:0032007 | Not Cancer Driver | No | 381 | 0.111 | 1292 | 161 | 0.125 | 1 |
TBC1D7 | TBC1D7 | Q9P0N9 | TBC1 domain family member 7 | chr6 | GO:0032007 | Not Cancer Driver | No | 51 | 0.174 | 1 | 0 | 0.0 | 0 |
TMEM127 | TMEM127 | O75204 | Transmembrane protein 127 | chr2 | GO:0032007 | Census | Yes | 24 | 0.101 | 41 | 5 | 0.122 | 7 |
TNFAIP8L1 | TNFAIP8L1 | Q8WVP5 | Tumor necrosis factor alpha-induced protein 8-like protein 1 | chr19 | GO:0032007 | Not Cancer Driver | No | 17 | 0.091 | 0 | 0 | 0.0 | 0 |
TSC1 | TSC1 | Q92574 | Hamartin | chr9 | GO:0032007 | Census, Compendium | Yes | 135 | 0.116 | 732 | 78 | 0.107 | 11 |
TSC2 | TSC2 | P49815 | Tuberin | chr16 | GO:0032007 | Census, Compendium | Yes | 192 | 0.106 | 563 | 50 | 0.089 | 53 |
UBR1 | UBR1 | Q8IWV7 | E3 ubiquitin-protein ligase UBR1 | chr15 | GO:0032007 | Not Cancer Driver | No | 170 | 0.097 | 165 | 15 | 0.091 | 18 |
UBR2 | UBR2 | Q8IWV8 | E3 ubiquitin-protein ligase UBR2 | chr6 | GO:0032007 | Not Cancer Driver | No | 172 | 0.098 | 228 | 30 | 0.132 | 0 |