Total number of protein in "GO:0032006" GO term: 58
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ARAF_ENST00000377045 | ARAF | P10398 | Serine/threonine-protein kinase A-Raf | chrX | GO:0032006 | Census, Compendium | Yes | 84 | 0.139 | 181 | 32 | 0.177 | 0 |
| ATM_ENST00000452508 | ATM | Q13315 | Serine-protein kinase ATM | chr11 | GO:0032006 | Census, Compendium | Yes | 469 | 0.153 | 225 | 39 | 0.173 | 41 |
| BMT2 | BMT2 | Q1RMZ1 | S-adenosylmethionine sensor upstream of mTORC1 | chr7 | GO:0032006 | Not Cancer Driver | No | 65 | 0.16 | 81 | 10 | 0.123 | 0 |
| C12orf66_ENST00000398055 | KICS2 | Q96MD2 | KICSTOR subunit 2 | chr12 | GO:0032006 | Not Cancer Driver | No | 61 | 0.137 | 35 | 6 | 0.171 | 0 |
| C9orf72 | C9orf72 | Q96LT7 | Guanine nucleotide exchange factor C9orf72 | chr9 | GO:0032006 | Not Cancer Driver | No | 64 | 0.133 | 11 | 0 | 0.0 | 0 |
| CASTOR1 | CASTOR1 | Q8WTX7 | Cytosolic arginine sensor for mTORC1 subunit 1 | chr22 | GO:0032006 | Not Cancer Driver | No | 27 | 0.082 | 39 | 5 | 0.128 | 0 |
| CASTOR3 | CASTOR3 | Q8NAP1 | Putative protein CASTOR 3 | chr7 | GO:0032006 | Not Cancer Driver | No | 18 | 0.11 | 1 | 0 | 0.0 | 0 |
| CLEC16A | CLEC16A | Q2KHT3 | Protein CLEC16A | chr16 | GO:0032006 | Not Cancer Driver | No | 149 | 0.142 | 374 | 53 | 0.142 | 0 |
| CTNS_ENST00000046640 | CTNS | O60931 | Cystinosin | chr17 | GO:0032006 | Not Cancer Driver | No | 34 | 0.093 | 0 | 0 | 0.0 | 31 |
| DDIT4 | DDIT4 | Q9NX09 | DNA damage-inducible transcript 4 protein | chr10 | GO:0032006 | Not Cancer Driver | No | 20 | 0.086 | 87 | 9 | 0.103 | 0 |
| DEPDC5_ENST00000382112 | DEPDC5 | O75140 | GATOR complex protein DEPDC5 | chr22 | GO:0032006 | Not Cancer Driver | No | 226 | 0.141 | 575 | 91 | 0.158 | 7 |
| DEPTOR | DEPTOR | Q8TB45 | DEP domain-containing mTOR-interacting protein | chr8 | GO:0032006 | Not Cancer Driver | No | 57 | 0.139 | 125 | 12 | 0.096 | 0 |
| DGKQ | DGKQ | P52824 | Diacylglycerol kinase theta | chr4 | GO:0032006 | Not Cancer Driver | No | 56 | 0.059 | 264 | 11 | 0.042 | 0 |
| DYRK3 | DYRK3 | O43781 | Dual specificity tyrosine-phosphorylation-regulated kinase 3 | chr1 | GO:0032006 | Not Cancer Driver | No | 87 | 0.148 | 193 | 20 | 0.104 | 0 |
| FAM83D | FAM83D | Q9H4H8 | Protein FAM83D | chr20 | GO:0032006 | Not Cancer Driver | No | 70 | 0.12 | 273 | 29 | 0.106 | 0 |
| FBXO9 | FBXO9 | Q9UK97 | F-box only protein 9 | chr6 | GO:0032006 | Not Cancer Driver | No | 49 | 0.11 | 110 | 7 | 0.064 | 0 |
| FLCN | FLCN | Q8NFG4 | Folliculin | chr17 | GO:0032006 | Census, Compendium | Yes | 59 | 0.102 | 157 | 19 | 0.121 | 5 |
| GBA_ENST00000368373 | GBA | P04062 | Lysosomal acid glucosylceramidase | chr1 | GO:0032006 | Not Cancer Driver | No | 74 | 0.138 | 38 | 5 | 0.132 | 171 |
| GNA12 | GNA12 | Q03113 | Guanine nucleotide-binding protein subunit alpha-12 | chr7 | GO:0032006 | Not Cancer Driver | No | 41 | 0.108 | 20 | 0 | 0.0 | 0 |
| GPAT3_ENST00000395226 | GPAT3 | Q53EU6 | Glycerol-3-phosphate acyltransferase 3 | chr4 | GO:0032006 | Not Cancer Driver | No | 56 | 0.129 | 3 | 0 | 0.0 | 0 |
| GPR137B | GPR137B | O60478 | Integral membrane protein GPR137B | chr1 | GO:0032006 | Not Cancer Driver | No | 49 | 0.123 | 47 | 1 | 0.021 | 0 |
| GPR137C | GPR137C | Q8N3F9 | Integral membrane protein GPR137C | chr14 | GO:0032006 | Not Cancer Driver | No | 41 | 0.096 | 47 | 0 | 0.0 | 0 |
| GPR137_ENST00000313074 | GPR137 | Q96N19 | Integral membrane protein GPR137 | chr11 | GO:0032006 | Not Cancer Driver | No | 66 | 0.158 | 41 | 11 | 0.268 | 0 |
| ITFG2 | ITFG2 | Q969R8 | KICSTOR complex protein ITFG2 | chr12 | GO:0032006 | Not Cancer Driver | No | 59 | 0.132 | 61 | 9 | 0.148 | 0 |
| KLHL22 | KLHL22 | Q53GT1 | Kelch-like protein 22 | chr22 | GO:0032006 | Not Cancer Driver | No | 90 | 0.142 | 50 | 8 | 0.16 | 0 |
| KPTN | KPTN | Q9Y664 | KICSTOR complex protein kaptin | chr19 | GO:0032006 | Not Cancer Driver | No | 44 | 0.101 | 21 | 2 | 0.095 | 0 |
| LAMTOR5_ENST00000602318 | LAMTOR5 | O43504 | Ragulator complex protein LAMTOR5 | chr1 | GO:0032006 | Not Cancer Driver | No | 10 | 0.11 | 17 | 0 | 0.0 | 0 |
| LARS | LARS1 | Q9P2J5 | Leucine--tRNA ligase, cytoplasmic | chr5 | GO:0032006 | Not Cancer Driver | No | 133 | 0.113 | 97 | 10 | 0.103 | 1 |
| MIOS_ENST00000405785 | MIOS | Q9NXC5 | GATOR complex protein MIOS | chr7 | GO:0032006 | Not Cancer Driver | No | 98 | 0.112 | 72 | 4 | 0.056 | 0 |
| NCKAP1L | NCKAP1L | P55160 | Nck-associated protein 1-like | chr12 | GO:0032006 | Not Cancer Driver | No | 247 | 0.219 | 51 | 10 | 0.196 | 4 |
| NPRL2 | NPRL2 | Q8WTW4 | GATOR complex protein NPRL2 | chr3 | GO:0032006 | Compendium | Yes | 37 | 0.097 | 10 | 3 | 0.3 | 1 |
| NPRL3_ENST00000611875 | NPRL3 | Q12980 | GATOR complex protein NPRL3 | chr16 | GO:0032006 | Not Cancer Driver | No | 45 | 0.079 | 158 | 22 | 0.139 | 0 |
| OTUD5 | OTUD5 | Q96G74 | OTU domain-containing protein 5 | chrX | GO:0032006 | Not Cancer Driver | No | 55 | 0.096 | 430 | 39 | 0.091 | 4 |
| PIH1D1 | PIH1D1 | Q9NWS0 | PIH1 domain-containing protein 1 | chr19 | GO:0032006 | Not Cancer Driver | No | 30 | 0.103 | 157 | 13 | 0.083 | 0 |
| PIP4P1_ENST00000250489 | PIP4P1 | Q86T03 | Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase | chr14 | GO:0032006 | Not Cancer Driver | No | 36 | 0.13 | 78 | 4 | 0.051 | 0 |
| PKHD1 | PKHD1 | P08F94 | Fibrocystin | chr6 | GO:0032006 | Not Cancer Driver | No | 778 | 0.191 | 413 | 81 | 0.196 | 93 |
| RFFL_ENST00000394597 | RFFL | Q8WZ73 | E3 ubiquitin-protein ligase rififylin | chr17 | GO:0032006 | Not Cancer Driver | No | 50 | 0.138 | 150 | 21 | 0.14 | 0 |
| RNF152 | RNF152 | Q8N8N0 | E3 ubiquitin-protein ligase RNF152 | chr18 | GO:0032006 | Not Cancer Driver | No | 61 | 0.3 | 34 | 11 | 0.324 | 0 |
| ROS1 | ROS1 | P08922 | Proto-oncogene tyrosine-protein kinase ROS | chr6 | GO:0032006 | Census | Yes | 498 | 0.212 | 191 | 55 | 0.288 | 0 |
| RRAGA | RRAGA | Q7L523 | Ras-related GTP-binding protein A | chr9 | GO:0032006 | Not Cancer Driver | No | 30 | 0.096 | 0 | 0 | 0.0 | 0 |
| RRAGB | RRAGB | Q5VZM2 | Ras-related GTP-binding protein B | chrX | GO:0032006 | Not Cancer Driver | No | 67 | 0.179 | 37 | 5 | 0.135 | 0 |
| RRAGC | RRAGC | Q9HB90 | Ras-related GTP-binding protein C | chr1 | GO:0032006 | Compendium | Yes | 29 | 0.073 | 61 | 1 | 0.016 | 0 |
| RRAGD | RRAGD | Q9NQL2 | Ras-related GTP-binding protein D | chr6 | GO:0032006 | Not Cancer Driver | No | 42 | 0.105 | 83 | 5 | 0.06 | 0 |
| SEH1L_ENST00000262124 | SEH1L | Q96EE3 | Nucleoporin SEH1 | chr18 | GO:0032006 | Not Cancer Driver | No | 40 | 0.111 | 71 | 11 | 0.155 | 0 |
| SESN1_ENST00000356644 | SESN1 | Q9Y6P5 | Sestrin-1 | chr6 | GO:0032006 | Not Cancer Driver | No | 45 | 0.091 | 48 | 4 | 0.083 | 0 |
| SESN2 | SESN2 | P58004 | Sestrin-2 | chr1 | GO:0032006 | Not Cancer Driver | No | 74 | 0.154 | 147 | 26 | 0.177 | 0 |
| SESN3 | SESN3 | P58005 | Sestrin-3 | chr11 | GO:0032006 | Not Cancer Driver | No | 84 | 0.171 | 44 | 4 | 0.091 | 0 |
| SIK3 | SIK3 | Q9Y2K2 | Serine/threonine-protein kinase SIK3 | chr11 | GO:0032006 | Not Cancer Driver | No | 143 | 0.108 | 964 | 107 | 0.111 | 1 |
| SMCR8 | SMCR8 | Q8TEV9 | Guanine nucleotide exchange protein SMCR8 | chr17 | GO:0032006 | Not Cancer Driver | No | 107 | 0.114 | 357 | 38 | 0.106 | 0 |
| STK11 | STK11 | Q15831 | Serine/threonine-protein kinase STK11 | chr19 | GO:0032006 | Census, Compendium | Yes | 75 | 0.173 | 135 | 14 | 0.104 | 9 |
| SZT2_ENST00000634258 | SZT2 | Q5T011 | KICSTOR complex protein SZT2 | chr1 | GO:0032006 | Not Cancer Driver | No | 381 | 0.111 | 1292 | 161 | 0.125 | 1 |
| TBCK_ENST00000432496 | TBCK | Q8TEA7 | TBC domain-containing protein kinase-like protein | chr4 | GO:0032006 | Not Cancer Driver | No | 115 | 0.129 | 88 | 9 | 0.102 | 2 |
| TELO2 | TELO2 | Q9Y4R8 | Telomere length regulation protein TEL2 homolog | chr16 | GO:0032006 | Not Cancer Driver | No | 113 | 0.135 | 154 | 23 | 0.149 | 5 |
| TMEM127 | TMEM127 | O75204 | Transmembrane protein 127 | chr2 | GO:0032006 | Census | Yes | 24 | 0.101 | 41 | 5 | 0.122 | 7 |
| TREM2 | TREM2 | Q9NZC2 | Triggering receptor expressed on myeloid cells 2 | chr6 | GO:0032006 | Not Cancer Driver | No | 43 | 0.187 | 27 | 2 | 0.074 | 1 |
| TTI1 | TTI1 | O43156 | TELO2-interacting protein 1 homolog | chr20 | GO:0032006 | Not Cancer Driver | No | 136 | 0.125 | 93 | 13 | 0.14 | 0 |
| WAC | WAC | Q9BTA9 | WW domain-containing adapter protein with coiled-coil | chr10 | GO:0032006 | Not Cancer Driver | No | 106 | 0.164 | 571 | 95 | 0.166 | 0 |
| ZMPSTE24 | ZMPSTE24 | O75844 | CAAX prenyl protease 1 homolog | chr1 | GO:0032006 | Not Cancer Driver | No | 67 | 0.141 | 23 | 0 | 0.0 | 3 |