Filter in search result
Please select a valid state.

Total number of protein in "GO:0031647" GO term:  127

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ADGRV1_ENST00000645211 ADGRV1 Q8WXG9 Adhesion G-protein coupled receptor V1 chr5 GO:0031647 Not Cancer Driver No 1124 0.178 496 77 0.155 2
ANK2 ANK2 Q01484 Ankyrin-2 chr4 GO:0031647 Not Cancer Driver No 770 0.195 2844 566 0.199 4
APOA2 APOA2 P02652 Apolipoprotein A-II chr1 GO:0031647 Not Cancer Driver No 13 0.13 0 0 0.0 0
APTX_ENST00000379819 APTX Q7Z2E3 Aprataxin chr9 GO:0031647 Not Cancer Driver No 36 0.101 101 6 0.059 9
ASPH ASPH Q12797 Aspartyl/asparaginyl beta-hydroxylase chr8 GO:0031647 Not Cancer Driver No 109 0.144 373 53 0.142 1
ATF7IP_ENST00000540793 ATF7IP Q6VMQ6 Activating transcription factor 7-interacting protein 1 chr12 GO:0031647 Compendium Yes 160 0.126 1136 139 0.122 0
AURKA_ENST00000395915 AURKA O14965 Aurora kinase A chr20 GO:0031647 Not Cancer Driver No 36 0.089 178 21 0.118 0
B4GALT5 B4GALT5 O43286 Beta-1,4-galactosyltransferase 5 chr20 GO:0031647 Not Cancer Driver No 53 0.137 20 1 0.05 0
BAG6 BAG6 P46379 Large proline-rich protein BAG6 chr6 GO:0031647 Not Cancer Driver No 98 0.087 861 79 0.092 0
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:0031647 Census, Compendium Yes 24 0.1 72 5 0.069 0
BMP2 BMP2 P12643 Bone morphogenetic protein 2 chr20 GO:0031647 Not Cancer Driver No 73 0.184 139 26 0.187 0
BTRC BTRC Q9Y297 F-box/WD repeat-containing protein 1A chr10 GO:0031647 Not Cancer Driver No 80 0.132 45 4 0.089 0
CAPN3 CAPN3 P20807 Calpain-3 chr15 GO:0031647 Not Cancer Driver No 111 0.135 168 11 0.065 52
CASP3 CASP3 P42574 Caspase-3 chr4 GO:0031647 Census Yes 32 0.116 62 5 0.081 0
CCAR2 CCAR2 Q8N163 Cell cycle and apoptosis regulator protein 2 chr8 GO:0031647 Not Cancer Driver No 102 0.111 528 62 0.117 0
CCDC88C CCDC88C Q9P219 Protein Daple chr14 GO:0031647 Not Cancer Driver No 270 0.133 1604 225 0.14 1
CD81 CD81 P60033 CD81 antigen chr11 GO:0031647 Not Cancer Driver No 28 0.119 0 0 0.0 0
CDC73 CDC73 Q6P1J9 Parafibromin chr1 GO:0031647 Census, Compendium Yes 110 0.207 210 39 0.186 2
CDKN2AIP CDKN2AIP Q9NXV6 CDKN2A-interacting protein chr4 GO:0031647 Not Cancer Driver No 53 0.091 352 38 0.108 0
CHFR CHFR Q96EP1 E3 ubiquitin-protein ligase CHFR chr12 GO:0031647 Not Cancer Driver No 85 0.128 341 54 0.158 0
CMTM6 CMTM6 Q9NX76 CKLF-like MARVEL transmembrane domain-containing protein 6 chr3 GO:0031647 Not Cancer Driver No 10 0.055 30 0 0.0 0
CREBBP CREBBP Q92793 CREB-binding protein chr16 GO:0031647 Census, Compendium Yes 412 0.169 1796 247 0.138 33
CTSA_ENST00000372459 CTSA P10619 Lysosomal protective protein chr20 GO:0031647 Not Cancer Driver No 59 0.123 14 1 0.071 12
CTSH CTSH P09668 Pro-cathepsin H chr15 GO:0031647 Not Cancer Driver No 45 0.134 4 0 0.0 0
CUL3 CUL3 Q13618 Cullin-3 chr2 GO:0031647 Census, Compendium Yes 123 0.16 167 23 0.138 3
DACT1 DACT1 Q9NYF0 Dapper homolog 1 chr14 GO:0031647 Not Cancer Driver No 163 0.195 598 127 0.212 1
DAD1 DAD1 P61803 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 chr14 GO:0031647 Not Cancer Driver No 7 0.062 0 0 0.0 0
DDI1 DDI1 Q8WTU0 Protein DDI1 homolog 1 chr11 GO:0031647 Not Cancer Driver No 151 0.381 166 73 0.44 0
DDI2 DDI2 Q5TDH0 Protein DDI1 homolog 2 chr1 GO:0031647 Not Cancer Driver No 47 0.118 187 30 0.16 0
DDOST_ENST00000375048 DDOST P39656 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit chr1 GO:0031647 Not Cancer Driver No 34 0.075 13 3 0.231 1
DDRGK1 DDRGK1 Q96HY6 DDRGK domain-containing protein 1 chr20 GO:0031647 Not Cancer Driver No 34 0.108 181 23 0.127 0
DERL1 DERL1 Q9BUN8 Derlin-1 chr8 GO:0031647 Not Cancer Driver No 28 0.112 11 1 0.091 0
DPM2 DPM2 O94777 Dolichol phosphate-mannose biosynthesis regulatory protein chr9 GO:0031647 Not Cancer Driver No 9 0.107 0 0 0.0 1
DPM3_ENST00000341298 DPM3 Q9P2X0 Dolichol-phosphate mannosyltransferase subunit 3 chr1 GO:0031647 Not Cancer Driver No 8 0.087 0 0 0.0 1
EP300 EP300 Q09472 Histone acetyltransferase p300 chr22 GO:0031647 Census, Compendium Yes 334 0.138 1790 196 0.109 1
FAM107A_ENST00000394481 FAM107A O95990 Actin-associated protein FAM107A chr3 GO:0031647 Not Cancer Driver No 25 0.174 141 24 0.17 0
FBXL3 FBXL3 Q9UKT7 F-box/LRR-repeat protein 3 chr13 GO:0031647 Not Cancer Driver No 49 0.114 30 6 0.2 1
FBXO4 FBXO4 Q9UKT5 F-box only protein 4 chr5 GO:0031647 Not Cancer Driver No 55 0.142 68 7 0.103 0
FBXO7 FBXO7 Q9Y3I1 F-box only protein 7 chr22 GO:0031647 Not Cancer Driver No 75 0.144 243 38 0.156 1
FBXW11 FBXW11 Q9UKB1 F-box/WD repeat-containing protein 11 chr5 GO:0031647 Not Cancer Driver No 75 0.138 20 3 0.15 7
FBXW7_ENST00000603841 FBXW7 Q969H0 F-box/WD repeat-containing protein 7 chr4 GO:0031647 Census, Compendium Yes 322 0.455 230 38 0.165 0
GET4 GET4 Q7L5D6 Golgi to ER traffic protein 4 homolog chr7 GO:0031647 Not Cancer Driver No 34 0.104 51 3 0.059 0
GGA3 GGA3 Q9NZ52 ADP-ribosylation factor-binding protein GGA3 chr17 GO:0031647 Not Cancer Driver No 73 0.101 419 41 0.098 0
GIPC1 GIPC1 O14908 PDZ domain-containing protein GIPC1 chr19 GO:0031647 Not Cancer Driver No 47 0.141 138 17 0.123 0
GNL3L_ENST00000360845 GNL3L Q9NVN8 Guanine nucleotide-binding protein-like 3-like protein chrX GO:0031647 Not Cancer Driver No 120 0.206 242 43 0.178 0
GSN GSN P06396 Gelsolin chr9 GO:0031647 Not Cancer Driver No 76 0.097 316 28 0.089 2
HDAC3 HDAC3 O15379 Histone deacetylase 3 chr5 GO:0031647 Not Cancer Driver No 65 0.152 61 8 0.131 0
HDAC6_ENST00000426196 HDAC6 Q9UBN7 Histone deacetylase 6 chrX GO:0031647 Not Cancer Driver No 178 0.147 409 59 0.144 0
HDAC8 HDAC8 Q9BY41 Histone deacetylase 8 chrX GO:0031647 Not Cancer Driver No 54 0.143 32 4 0.125 4
HSPA8_ENST00000532636 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 GO:0031647 Not Cancer Driver No 149 0.231 251 52 0.207 0
HTT HTT P42858 Huntingtin chr4 GO:0031647 Not Cancer Driver No 336 0.107 666 69 0.104 2
INSC INSC Q1MX18 Protein inscuteable homolog chr11 GO:0031647 Not Cancer Driver No 125 0.216 34 13 0.382 0
IRGM IRGM A1A4Y4 Immunity-related GTPase family M protein chr5 GO:0031647 Not Cancer Driver No 9 0.05 45 1 0.022 0
ISOC2_ENST00000425675 ISOC2 Q96AB3 Isochorismatase domain-containing protein 2 chr19 GO:0031647 Not Cancer Driver No 24 0.117 8 0 0.0 0
KAT2A KAT2A Q92830 Histone acetyltransferase KAT2A chr17 GO:0031647 Not Cancer Driver No 88 0.105 251 17 0.068 0
KDM8_ENST00000286096 KDM8 Q8N371 Bifunctional peptidase and arginyl-hydroxylase JMJD5 chr16 GO:0031647 Not Cancer Driver No 52 0.125 29 6 0.207 0
KHDRBS1 KHDRBS1 Q07666 KH domain-containing, RNA-binding, signal transduction-associated protein 1 chr1 GO:0031647 Not Cancer Driver No 53 0.12 362 43 0.119 0
KRAS KRAS P01116 GTPase KRas chr12 GO:0031647 Census, Compendium Yes 788 4.169 7 2 0.286 27
LAMP2_ENST00000200639 LAMP2 P13473 Lysosome-associated membrane glycoprotein 2 chrX GO:0031647 Not Cancer Driver No 43 0.105 55 7 0.127 1
LMNA LMNA P02545 Prelamin-A/C chr1 GO:0031647 Census Yes 68 0.102 544 49 0.09 131
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 GO:0031647 Not Cancer Driver No 519 0.205 90 17 0.189 23
LSS LSS P48449 Lanosterol synthase chr21 GO:0031647 Not Cancer Driver No 85 0.116 31 5 0.161 6
MAPK1_ENST00000398822 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 GO:0031647 Census, Compendium Yes 62 0.172 2 0 0.0 7
MDM2_ENST00000539479 MDM2 Q00987 E3 ubiquitin-protein ligase Mdm2 chr12 GO:0031647 Census, Compendium Yes 56 0.114 297 37 0.125 0
MOSMO MOSMO Q8NHV5 Modulator of smoothened protein chr16 GO:0031647 Not Cancer Driver No 3 0.018 0 0 0.0 0
MUL1 MUL1 Q969V5 Mitochondrial ubiquitin ligase activator of NFKB 1 chr1 GO:0031647 Not Cancer Driver No 48 0.136 16 2 0.125 0
MYLIP MYLIP Q8WY64 E3 ubiquitin-protein ligase MYLIP chr6 GO:0031647 Not Cancer Driver No 56 0.126 11 2 0.182 0
NDC80 NDC80 O14777 Kinetochore protein NDC80 homolog chr18 GO:0031647 Not Cancer Driver No 80 0.125 313 45 0.144 0
NEDD4L NEDD4L Q96PU5 E3 ubiquitin-protein ligase NEDD4-like chr18 GO:0031647 Not Cancer Driver No 126 0.129 463 60 0.13 4
NF2 NF2 P35240 Merlin chr22 GO:0031647 Census, Compendium Yes 69 0.116 252 26 0.103 16
NR1D1 NR1D1 P20393 Nuclear receptor subfamily 1 group D member 1 chr17 GO:0031647 Not Cancer Driver No 81 0.132 348 49 0.141 0
PEX2 PEX2 P28328 Peroxisome biogenesis factor 2 chr8 GO:0031647 Not Cancer Driver No 50 0.164 5 1 0.2 1
PIN1 PIN1 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 chr19 GO:0031647 Not Cancer Driver No 17 0.104 115 12 0.104 0
PINX1 PINX1 Q96BK5 PIN2/TERF1-interacting telomerase inhibitor 1 chr8 GO:0031647 Not Cancer Driver No 66 0.201 328 66 0.201 0
PLK1 PLK1 P53350 Serine/threonine-protein kinase PLK1 chr16 GO:0031647 Not Cancer Driver No 87 0.144 119 13 0.109 0
PRKD1_ENST00000616995 PRKD1 Q15139 Serine/threonine-protein kinase D1 chr14 GO:0031647 Census Yes 201 0.22 189 33 0.175 2
PRKDC PRKDC P78527 DNA-dependent protein kinase catalytic subunit chr8 GO:0031647 Not Cancer Driver No 538 0.13 421 61 0.145 2
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 GO:0031647 Not Cancer Driver No 110 0.237 78 15 0.192 31
PRNP PRNP P04156 Major prion protein chr20 GO:0031647 Not Cancer Driver No 36 0.142 115 7 0.061 18
PTEN PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 GO:0031647 Census, Compendium Yes 505 1.253 76 4 0.053 41
PYCARD PYCARD Q9ULZ3 Apoptosis-associated speck-like protein containing a CARD chr16 GO:0031647 Not Cancer Driver No 16 0.082 39 4 0.103 0
PYHIN1 PYHIN1 Q6K0P9 Pyrin and HIN domain-containing protein 1 chr1 GO:0031647 Not Cancer Driver No 174 0.354 291 99 0.34 0
QRSL1 QRSL1 Q9H0R6 Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial chr6 GO:0031647 Not Cancer Driver No 63 0.119 63 4 0.063 2
RAD23A RAD23A P54725 UV excision repair protein RAD23 homolog A chr19 GO:0031647 Not Cancer Driver No 50 0.138 283 41 0.145 0
RNF128 RNF128 Q8TEB7 E3 ubiquitin-protein ligase RNF128 chrX GO:0031647 Not Cancer Driver No 61 0.143 123 15 0.122 0
RNF139 RNF139 Q8WU17 E3 ubiquitin-protein ligase RNF139 chr8 GO:0031647 Not Cancer Driver No 76 0.114 68 4 0.059 0
RNF149 RNF149 Q8NC42 E3 ubiquitin-protein ligase RNF149 chr2 GO:0031647 Not Cancer Driver No 41 0.102 102 10 0.098 0
RNF5 RNF5 Q99942 E3 ubiquitin-protein ligase RNF5 chr6 GO:0031647 Not Cancer Driver No 17 0.094 69 3 0.043 0
SENP2 SENP2 Q9HC62 Sentrin-specific protease 2 chr3 GO:0031647 Not Cancer Driver No 73 0.124 285 38 0.133 0
SERF1B SERF1B O75920 Small EDRK-rich factor 1 chr5 GO:0031647 Not Cancer Driver No 2 0.018 61 1 0.016 0
SERF2_ENST00000381359 SERF2 P84101 Small EDRK-rich factor 2 chr15 GO:0031647 Not Cancer Driver No 11 0.186 59 11 0.186 0
SH3GLB1_ENST00000370558 SH3GLB1 Q9Y371 Endophilin-B1 chr1 GO:0031647 Not Cancer Driver No 41 0.112 82 10 0.122 0
SIAH3 SIAH3 Q8IW03 Seven in absentia homolog 3 chr13 GO:0031647 Not Cancer Driver No 60 0.223 51 9 0.176 0
SIRT1 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 GO:0031647 Not Cancer Driver No 70 0.094 435 31 0.071 0
SIRT6 SIRT6 Q8N6T7 NAD-dependent protein deacylase sirtuin-6 chr19 GO:0031647 Not Cancer Driver No 33 0.093 164 12 0.073 0
SLC51B SLC51B Q86UW2 Organic solute transporter subunit beta chr15 GO:0031647 Not Cancer Driver No 9 0.07 58 5 0.086 0
SNCA_ENST00000506244 SNCA P37840 Alpha-synuclein chr4 GO:0031647 Not Cancer Driver No 21 0.15 107 13 0.121 5
SOX17 SOX17 Q9H6I2 Transcription factor SOX-17 chr8 GO:0031647 Compendium Yes 81 0.196 378 59 0.156 2
SOX4 SOX4 Q06945 Transcription factor SOX-4 chr6 GO:0031647 Not Cancer Driver No 28 0.059 400 24 0.06 4
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:0031647 Census Yes 53 0.099 130 11 0.085 1
SREBF1_ENST00000261646 SREBF1 P36956 Sterol regulatory element-binding protein 1 chr17 GO:0031647 Not Cancer Driver No 127 0.111 528 64 0.121 4
STUB1 STUB1 Q9UNE7 E3 ubiquitin-protein ligase CHIP chr16 GO:0031647 Not Cancer Driver No 35 0.116 112 14 0.125 12
SUGT1 SUGT1 Q9Y2Z0 Protein SGT1 homolog chr13 GO:0031647 Not Cancer Driver No 31 0.085 119 5 0.042 0
TADA3 TADA3 O75528 Transcriptional adapter 3 chr3 GO:0031647 Not Cancer Driver No 54 0.125 353 43 0.122 0
TARDBP TARDBP Q13148 TAR DNA-binding protein 43 chr1 GO:0031647 Not Cancer Driver No 51 0.123 202 15 0.074 27
TERT TERT O14746 Telomerase reverse transcriptase chr5 GO:0031647 Census Yes 110 0.097 212 16 0.075 31
TF TF P02787 Serotransferrin chr3 GO:0031647 Not Cancer Driver No 135 0.193 21 5 0.238 2
TMEM183A TMEM183A Q8IXX5 Transmembrane protein 183A chr1 GO:0031647 Not Cancer Driver No 30 0.08 127 9 0.071 0
TMEM25_ENST00000313236 TMEM25 Q86YD3 Transmembrane protein 25 chr11 GO:0031647 Not Cancer Driver No 50 0.137 128 11 0.086 0
TOMM7 TOMM7 Q9P0U1 Mitochondrial import receptor subunit TOM7 homolog chr7 GO:0031647 Not Cancer Driver No 7 0.127 0 0 0.0 0
TPR TPR P12270 Nucleoprotein TPR chr1 GO:0031647 Census Yes 311 0.132 1990 266 0.134 0
TRIM21 TRIM21 P19474 E3 ubiquitin-protein ligase TRIM21 chr11 GO:0031647 Not Cancer Driver No 85 0.179 49 7 0.143 0
TRIM24 TRIM24 O15164 Transcription intermediary factor 1-alpha chr7 GO:0031647 Census, Compendium Yes 120 0.114 537 61 0.114 0
UBL4A UBL4A P11441 Ubiquitin-like protein 4A chrX GO:0031647 Not Cancer Driver No 22 0.14 16 5 0.312 0
USP13 USP13 Q92995 Ubiquitin carboxyl-terminal hydrolase 13 chr3 GO:0031647 Not Cancer Driver No 121 0.14 224 42 0.188 0
USP19_ENST00000398888 USP19 O94966 Ubiquitin carboxyl-terminal hydrolase 19 chr3 GO:0031647 Not Cancer Driver No 161 0.122 539 68 0.126 0
USP28 USP28 Q96RU2 Ubiquitin carboxyl-terminal hydrolase 28 chr11 GO:0031647 Not Cancer Driver No 151 0.14 311 25 0.08 0
USP3 USP3 Q9Y6I4 Ubiquitin carboxyl-terminal hydrolase 3 chr15 GO:0031647 Not Cancer Driver No 60 0.115 45 4 0.089 0
USP36_ENST00000312010 USP36 Q9P275 Ubiquitin carboxyl-terminal hydrolase 36 chr17 GO:0031647 Not Cancer Driver No 151 0.134 718 91 0.127 0
USP4 USP4 Q13107 Ubiquitin carboxyl-terminal hydrolase 4 chr3 GO:0031647 Not Cancer Driver No 102 0.106 286 22 0.077 0
USP40_ENST00000427112 USP40 Q9NVE5 Ubiquitin carboxyl-terminal hydrolase 40 chr2 GO:0031647 Not Cancer Driver No 153 0.124 218 26 0.119 0
USP47 USP47 Q96K76 Ubiquitin carboxyl-terminal hydrolase 47 chr11 GO:0031647 Not Cancer Driver No 137 0.1 425 39 0.092 0
USP7 USP7 Q93009 Ubiquitin carboxyl-terminal hydrolase 7 chr16 GO:0031647 Not Cancer Driver No 170 0.154 215 45 0.209 0
USP8 USP8 P40818 Ubiquitin carboxyl-terminal hydrolase 8 chr15 GO:0031647 Census, Compendium Yes 122 0.109 602 69 0.115 0
UTP25 UTP25 Q68CQ4 U3 small nucleolar RNA-associated protein 25 homolog chr1 GO:0031647 Not Cancer Driver No 116 0.153 277 28 0.101 0
VPS11 VPS11 Q9H270 Vacuolar protein sorting-associated protein 11 homolog chr11 GO:0031647 Not Cancer Driver No 96 0.102 118 6 0.051 1
VPS35 VPS35 Q96QK1 Vacuolar protein sorting-associated protein 35 chr16 GO:0031647 Not Cancer Driver No 68 0.085 99 9 0.091 1