Total number of protein in "GO:0031532" GO term: 58
Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ANTXR1 | ANTXR1 | Q9H6X2 | Anthrax toxin receptor 1 | chr2 | GO:0031532 | Not Cancer Driver | No | 105 | 0.186 | 183 | 44 | 0.24 | 0 |
ANXA1_ENST00000257497 | ANXA1 | P04083 | Annexin A1 | chr9 | GO:0031532 | Not Cancer Driver | No | 59 | 0.171 | 61 | 12 | 0.197 | 0 |
ASB2 | ASB2 | Q96Q27 | Ankyrin repeat and SOCS box protein 2 | chr14 | GO:0031532 | Not Cancer Driver | No | 90 | 0.142 | 167 | 19 | 0.114 | 0 |
ATP2C1_ENST00000508532 | ATP2C1 | P98194 | Calcium-transporting ATPase type 2C member 1 | chr3 | GO:0031532 | Not Cancer Driver | No | 125 | 0.136 | 44 | 5 | 0.114 | 20 |
AUTS2 | AUTS2 | Q8WXX7 | Autism susceptibility gene 2 protein | chr7 | GO:0031532 | Not Cancer Driver | No | 219 | 0.174 | 1218 | 213 | 0.175 | 0 |
BRSK2_ENST00000528841 | BRSK2 | Q8IWQ3 | Serine/threonine-protein kinase BRSK2 | chr11 | GO:0031532 | Not Cancer Driver | No | 90 | 0.122 | 321 | 39 | 0.121 | 0 |
CAPN10 | CAPN10 | Q9HC96 | Calpain-10 | chr2 | GO:0031532 | Not Cancer Driver | No | 87 | 0.129 | 52 | 6 | 0.115 | 0 |
CDC42BPA_ENST00000334218 | CDC42BPA | Q5VT25 | Serine/threonine-protein kinase MRCK alpha | chr1 | GO:0031532 | Not Cancer Driver | No | 215 | 0.124 | 717 | 80 | 0.112 | 0 |
CDC42BPB | CDC42BPB | Q9Y5S2 | Serine/threonine-protein kinase MRCK beta | chr14 | GO:0031532 | Not Cancer Driver | No | 185 | 0.108 | 696 | 92 | 0.132 | 0 |
CDC42BPG | CDC42BPG | Q6DT37 | Serine/threonine-protein kinase MRCK gamma | chr11 | GO:0031532 | Not Cancer Driver | No | 166 | 0.107 | 736 | 79 | 0.107 | 0 |
CLDN19 | CLDN19 | Q8N6F1 | Claudin-19 | chr1 | GO:0031532 | Not Cancer Driver | No | 27 | 0.121 | 20 | 2 | 0.1 | 3 |
CLDN3 | CLDN3 | O15551 | Claudin-3 | chr7 | GO:0031532 | Not Cancer Driver | No | 12 | 0.055 | 0 | 0 | 0.0 | 0 |
CTTN_ENST00000301843 | CTTN | Q14247 | Src substrate cortactin | chr11 | GO:0031532 | Not Cancer Driver | No | 78 | 0.142 | 465 | 56 | 0.12 | 0 |
CXADR | CXADR | P78310 | Coxsackievirus and adenovirus receptor | chr21 | GO:0031532 | Not Cancer Driver | No | 51 | 0.14 | 98 | 19 | 0.194 | 0 |
DTNBP1 | DTNBP1 | Q96EV8 | Dysbindin | chr6 | GO:0031532 | Not Cancer Driver | No | 49 | 0.14 | 210 | 25 | 0.119 | 0 |
EPS8_ENST00000645775 | EPS8 | Q12929 | Epidermal growth factor receptor kinase substrate 8 | chr12 | GO:0031532 | Not Cancer Driver | No | 106 | 0.129 | 459 | 54 | 0.118 | 0 |
EZR | EZR | P15311 | Ezrin | chr6 | GO:0031532 | Census | Yes | 66 | 0.113 | 295 | 35 | 0.119 | 0 |
FARP2 | FARP2 | O94887 | FERM, ARHGEF and pleckstrin domain-containing protein 2 | chr2 | GO:0031532 | Not Cancer Driver | No | 133 | 0.126 | 250 | 39 | 0.156 | 0 |
FER | FER | P16591 | Tyrosine-protein kinase Fer | chr5 | GO:0031532 | Not Cancer Driver | No | 114 | 0.139 | 145 | 21 | 0.145 | 0 |
FGF10 | FGF10 | O15520 | Fibroblast growth factor 10 | chr5 | GO:0031532 | Not Cancer Driver | No | 56 | 0.269 | 34 | 11 | 0.324 | 2 |
FGF7 | FGF7 | P21781 | Fibroblast growth factor 7 | chr15 | GO:0031532 | Not Cancer Driver | No | 38 | 0.196 | 22 | 4 | 0.182 | 0 |
FLNA | FLNA | P21333 | Filamin-A | chrX | GO:0031532 | Census | Yes | 416 | 0.157 | 1456 | 214 | 0.147 | 28 |
GAB1_ENST00000262994 | GAB1 | Q13480 | GRB2-associated-binding protein 1 | chr4 | GO:0031532 | Not Cancer Driver | No | 79 | 0.114 | 570 | 68 | 0.119 | 1 |
GPR65 | GPR65 | Q8IYL9 | Psychosine receptor | chr14 | GO:0031532 | Not Cancer Driver | No | 70 | 0.208 | 0 | 0 | 0.0 | 0 |
GRB2_ENST00000392564 | GRB2 | P62993 | Growth factor receptor-bound protein 2 | chr17 | GO:0031532 | Not Cancer Driver | No | 28 | 0.129 | 10 | 1 | 0.1 | 0 |
INSRR | INSRR | P14616 | Insulin receptor-related protein | chr1 | GO:0031532 | Not Cancer Driver | No | 262 | 0.202 | 228 | 37 | 0.162 | 0 |
KIT | KIT | P10721 | Mast/stem cell growth factor receptor Kit | chr4 | GO:0031532 | Census, Compendium | Yes | 226 | 0.232 | 83 | 33 | 0.398 | 21 |
MICALL2 | MICALL2 | Q8IY33 | MICAL-like protein 2 | chr7 | GO:0031532 | Not Cancer Driver | No | 110 | 0.122 | 675 | 88 | 0.13 | 0 |
MINK1 | MINK1 | Q8N4C8 | Misshapen-like kinase 1 | chr17 | GO:0031532 | Not Cancer Driver | No | 113 | 0.085 | 740 | 56 | 0.076 | 0 |
MKLN1 | MKLN1 | Q9UL63 | Muskelin | chr7 | GO:0031532 | Not Cancer Driver | No | 85 | 0.116 | 91 | 13 | 0.143 | 0 |
MYH9 | MYH9 | P35579 | Myosin-9 | chr22 | GO:0031532 | Census, Compendium | Yes | 310 | 0.158 | 1120 | 160 | 0.143 | 17 |
NPHS2 | NPHS2 | Q9NP85 | Podocin | chr1 | GO:0031532 | Not Cancer Driver | No | 72 | 0.188 | 130 | 18 | 0.138 | 50 |
NRK | NRK | Q7Z2Y5 | Nik-related protein kinase | chrX | GO:0031532 | Compendium | Yes | 315 | 0.199 | 812 | 159 | 0.196 | 0 |
NRP1 | NRP1 | O14786 | Neuropilin-1 | chr10 | GO:0031532 | Compendium | Yes | 146 | 0.158 | 211 | 31 | 0.147 | 0 |
PAK1_ENST00000356341 | PAK1 | Q13153 | Serine/threonine-protein kinase PAK 1 | chr11 | GO:0031532 | Not Cancer Driver | No | 57 | 0.105 | 299 | 30 | 0.1 | 2 |
PARVB_ENST00000338758 | PARVB | Q9HBI1 | Beta-parvin | chr22 | GO:0031532 | Not Cancer Driver | No | 45 | 0.124 | 83 | 9 | 0.108 | 0 |
PARVG_ENST00000422871 | PARVG | Q9HBI0 | Gamma-parvin | chr22 | GO:0031532 | Not Cancer Driver | No | 54 | 0.163 | 44 | 9 | 0.205 | 0 |
PDLIM4 | PDLIM4 | P50479 | PDZ and LIM domain protein 4 | chr5 | GO:0031532 | Not Cancer Driver | No | 42 | 0.127 | 238 | 28 | 0.118 | 0 |
PHACTR1 | PHACTR1 | Q9C0D0 | Phosphatase and actin regulator 1 | chr6 | GO:0031532 | Not Cancer Driver | No | 81 | 0.14 | 447 | 59 | 0.132 | 3 |
PIP5K1A | PIP5K1A | Q99755 | Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha | chr1 | GO:0031532 | Not Cancer Driver | No | 74 | 0.132 | 216 | 29 | 0.134 | 0 |
PLEC | PLEC | Q15149 | Plectin | chr8 | GO:0031532 | Not Cancer Driver | No | 677 | 0.145 | 2130 | 272 | 0.128 | 2 |
PLEK | PLEK | P08567 | Pleckstrin | chr2 | GO:0031532 | Not Cancer Driver | No | 81 | 0.231 | 39 | 9 | 0.231 | 0 |
PLEK2 | PLEK2 | Q9NYT0 | Pleckstrin-2 | chr14 | GO:0031532 | Not Cancer Driver | No | 41 | 0.116 | 25 | 5 | 0.2 | 0 |
PTK7_ENST00000230419 | PTK7 | Q13308 | Inactive tyrosine-protein kinase 7 | chr6 | GO:0031532 | Not Cancer Driver | No | 153 | 0.143 | 359 | 58 | 0.162 | 0 |
PTPN1 | PTPN1 | P18031 | Tyrosine-protein phosphatase non-receptor type 1 | chr20 | GO:0031532 | Not Cancer Driver | No | 49 | 0.113 | 140 | 25 | 0.179 | 0 |
RALA | RALA | P11233 | Ras-related protein Ral-A | chr7 | GO:0031532 | Not Cancer Driver | No | 34 | 0.165 | 34 | 3 | 0.088 | 5 |
RAP2A | RAP2A | P10114 | Ras-related protein Rap-2a | chr13 | GO:0031532 | Not Cancer Driver | No | 15 | 0.082 | 9 | 0 | 0.0 | 0 |
RHOA | RHOA | P61586 | Transforming protein RhoA | chr3 | GO:0031532 | Census, Compendium | Yes | 99 | 0.513 | 46 | 13 | 0.283 | 2 |
RICTOR_ENST00000357387 | RICTOR | Q6R327 | Rapamycin-insensitive companion of mTOR | chr5 | GO:0031532 | Not Cancer Driver | No | 212 | 0.124 | 366 | 50 | 0.137 | 0 |
S1PR1 | S1PR1 | P21453 | Sphingosine 1-phosphate receptor 1 | chr1 | GO:0031532 | Not Cancer Driver | No | 86 | 0.225 | 29 | 6 | 0.207 | 0 |
S1PR2 | S1PR2 | O95136 | Sphingosine 1-phosphate receptor 2 | chr19 | GO:0031532 | Not Cancer Driver | No | 38 | 0.108 | 16 | 3 | 0.188 | 2 |
SHC1_ENST00000368445 | SHC1 | P29353 | SHC-transforming protein 1 | chr1 | GO:0031532 | Not Cancer Driver | No | 84 | 0.144 | 397 | 58 | 0.146 | 0 |
SIPA1L1 | SIPA1L1 | O43166 | Signal-induced proliferation-associated 1-like protein 1 | chr14 | GO:0031532 | Not Cancer Driver | No | 321 | 0.178 | 1175 | 226 | 0.192 | 0 |
SYDE1 | SYDE1 | Q6ZW31 | Rho GTPase-activating protein SYDE1 | chr19 | GO:0031532 | Not Cancer Driver | No | 62 | 0.084 | 412 | 27 | 0.066 | 0 |
THSD7A | THSD7A | Q9UPZ6 | Thrombospondin type-1 domain-containing protein 7A | chr7 | GO:0031532 | Not Cancer Driver | No | 408 | 0.246 | 224 | 74 | 0.33 | 0 |
THSD7B | THSD7B | Q9C0I4 | Thrombospondin type-1 domain-containing protein 7B | chr2 | GO:0031532 | Not Cancer Driver | No | 652 | 0.406 | 94 | 19 | 0.202 | 0 |
TNIK | TNIK | Q9UKE5 | TRAF2 and NCK-interacting protein kinase | chr3 | GO:0031532 | Not Cancer Driver | No | 254 | 0.187 | 781 | 156 | 0.2 | 0 |
TRPV4 | TRPV4 | Q9HBA0 | Transient receptor potential cation channel subfamily V member 4 | chr12 | GO:0031532 | Not Cancer Driver | No | 142 | 0.163 | 231 | 34 | 0.147 | 44 |