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Total number of protein in "GO:0031490" GO term:  103

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ACTB_ENST00000646664 ACTB P60709 Actin, cytoplasmic 1 chr7 GO:0031490 Not Cancer Driver No 112 0.299 43 5 0.116 5
ACTL6A ACTL6A O96019 Actin-like protein 6A chr3 GO:0031490 Not Cancer Driver No 61 0.142 74 15 0.203 0
ACTN4 ACTN4 O43707 Alpha-actinin-4 chr19 GO:0031490 Not Cancer Driver No 131 0.144 244 42 0.172 8
APEX1_ENST00000555414 APEX1 P27695 DNA-(apurinic or apyrimidinic site) endonuclease chr14 GO:0031490 Not Cancer Driver No 34 0.107 103 14 0.136 0
ATOH1 ATOH1 Q92858 Transcription factor ATOH1 chr4 GO:0031490 Not Cancer Driver No 63 0.178 327 55 0.168 0
BCL6_ENST00000232014 BCL6 P41182 B-cell lymphoma 6 protein chr3 GO:0031490 Census, Compendium Yes 134 0.19 328 67 0.204 0
CHD4 CHD4 Q14839 Chromodomain-helicase-DNA-binding protein 4 chr12 GO:0031490 Census, Compendium Yes 419 0.219 974 177 0.182 6
CLOCK CLOCK O15516 Circadian locomoter output cycles protein kaput chr4 GO:0031490 Not Cancer Driver No 83 0.098 458 38 0.083 0
CREBBP CREBBP Q92793 CREB-binding protein chr16 GO:0031490 Census, Compendium Yes 412 0.169 1796 247 0.138 33
CTCF CTCF P49711 Transcriptional repressor CTCF chr16 GO:0031490 Census, Compendium Yes 151 0.208 481 83 0.173 1
CTCFL_ENST00000371196 CTCFL Q8NI51 Transcriptional repressor CTCFL chr20 GO:0031490 Not Cancer Driver No 136 0.205 266 61 0.229 0
DHX9 DHX9 Q08211 ATP-dependent RNA helicase A chr1 GO:0031490 Compendium Yes 182 0.143 331 42 0.127 0
EP300 EP300 Q09472 Histone acetyltransferase p300 chr22 GO:0031490 Census, Compendium Yes 334 0.138 1790 196 0.109 1
EZH2_ENST00000460911 EZH2 Q15910 Histone-lysine N-methyltransferase EZH2 chr7 GO:0031490 Census, Compendium Yes 120 0.161 284 44 0.155 11
FOXC2 FOXC2 Q99958 Forkhead box protein C2 chr16 GO:0031490 Not Cancer Driver No 63 0.126 369 33 0.089 1
FOXO1 FOXO1 Q12778 Forkhead box protein O1 chr13 GO:0031490 Census, Compendium Yes 81 0.124 584 75 0.128 0
FOXO3 FOXO3 O43524 Forkhead box protein O3 chr6 GO:0031490 Census, Compendium Yes 70 0.104 595 68 0.114 0
GATA1 GATA1 P15976 Erythroid transcription factor chrX GO:0031490 Census, Compendium Yes 68 0.165 242 41 0.169 5
GATAD2B_ENST00000634544 GATAD2B Q8WXI9 Transcriptional repressor p66-beta chr1 GO:0031490 Not Cancer Driver No 76 0.128 510 67 0.131 0
GRHL1 GRHL1 Q9NZI5 Grainyhead-like protein 1 homolog chr2 GO:0031490 Not Cancer Driver No 99 0.16 256 36 0.141 0
GRHL2 GRHL2 Q6ISB3 Grainyhead-like protein 2 homolog chr8 GO:0031490 Not Cancer Driver No 95 0.152 258 43 0.167 2
GRHL3 GRHL3 Q8TE85 Grainyhead-like protein 3 homolog chr1 GO:0031490 Not Cancer Driver No 83 0.133 291 38 0.131 3
H1F0 H1-0 P07305 Histone H1.0 chr22 GO:0031490 Not Cancer Driver No 16 0.082 194 16 0.082 0
H1FOO H1-8 Q8IZA3 Histone H1.8 chr3 GO:0031490 Not Cancer Driver No 28 0.081 322 26 0.081 0
H1FX H1-10 Q92522 Histone H1.10 chr3 GO:0031490 Not Cancer Driver No 12 0.056 198 12 0.061 0
H2AFY MACROH2A1 O75367 Core histone macro-H2A.1 chr5 GO:0031490 Not Cancer Driver No 46 0.124 125 19 0.152 0
H2AFY2 MACROH2A2 Q9P0M6 Core histone macro-H2A.2 chr10 GO:0031490 Not Cancer Driver No 59 0.159 171 32 0.187 0
H2AFZ H2AZ1 P0C0S5 Histone H2A.Z chr4 GO:0031490 Not Cancer Driver No 23 0.18 71 16 0.225 0
H3F3A_ENST00000366816 H3-3B P84243 Histone H3.3 chr1 GO:0031490 Not Cancer Driver No 32 0.235 51 22 0.431 3
H3F3B_ENST00000589599 H3-3B P84243 Histone H3.3 chr17 GO:0031490 Not Cancer Driver No 28 0.206 51 14 0.275 3
H3F3C H3-5 Q6NXT2 Histone H3.3C chr12 GO:0031490 Not Cancer Driver No 38 0.281 50 10 0.2 0
HDAC1 HDAC1 Q13547 Histone deacetylase 1 chr1 GO:0031490 Not Cancer Driver No 47 0.098 135 10 0.074 0
HDAC2 HDAC2 Q92769 Histone deacetylase 2 chr6 GO:0031490 Not Cancer Driver No 46 0.094 145 14 0.097 0
HIST1H1A H1-1 Q02539 Histone H1.1 chr6 GO:0031490 Not Cancer Driver No 37 0.172 210 35 0.167 0
HIST1H1B H1-5 P16401 Histone H1.5 chr6 GO:0031490 Not Cancer Driver No 66 0.292 224 66 0.295 0
HIST1H1C H1-2 P16403 Histone H1.2 chr6 GO:0031490 Not Cancer Driver No 79 0.371 211 78 0.37 0
HIST1H1D H1-3 P16402 Histone H1.3 chr6 GO:0031490 Not Cancer Driver No 49 0.222 215 47 0.219 0
HIST1H1E H1-4 P10412 Histone H1.4 chr6 GO:0031490 Not Cancer Driver No 66 0.301 213 63 0.296 0
HIST1H1T H1-6 P22492 Histone H1t chr6 GO:0031490 Not Cancer Driver No 49 0.237 158 38 0.241 0
HMGA2_ENST00000403681 HMGA2 P52926 High mobility group protein HMGI-C chr12 GO:0031490 Census Yes 12 0.11 109 12 0.11 0
HMGN1 HMGN1 P05114 Non-histone chromosomal protein HMG-14 chr21 GO:0031490 Not Cancer Driver No 12 0.12 100 12 0.12 0
HMGN2 HMGN2 P05204 Non-histone chromosomal protein HMG-17 chr1 GO:0031490 Not Cancer Driver No 10 0.111 90 10 0.111 0
HMGN3_ENST00000344726 HMGN3 Q15651 High mobility group nucleosome-binding domain-containing protein 3 chr6 GO:0031490 Not Cancer Driver No 14 0.141 99 14 0.141 0
HMGN4 HMGN4 O00479 High mobility group nucleosome-binding domain-containing protein 4 chr6 GO:0031490 Not Cancer Driver No 9 0.1 90 9 0.1 0
HMGN5 HMGN5 P82970 High mobility group nucleosome-binding domain-containing protein 5 chrX GO:0031490 Not Cancer Driver No 27 0.096 282 27 0.096 0
HNRNPC_ENST00000420743 HNRNPC P07910 Heterogeneous nuclear ribonucleoproteins C1/C2 chr14 GO:0031490 Not Cancer Driver No 42 0.137 227 35 0.154 0
HNRNPU HNRNPU Q00839 Heterogeneous nuclear ribonucleoprotein U chr1 GO:0031490 Not Cancer Driver No 77 0.093 504 45 0.089 0
HR HR O43593 Lysine-specific demethylase hairless chr8 GO:0031490 Not Cancer Driver No 130 0.109 587 74 0.126 3
HSF1 HSF1 Q00613 Heat shock factor protein 1 chr8 GO:0031490 Not Cancer Driver No 59 0.112 335 37 0.11 0
INSM1 INSM1 Q01101 Insulinoma-associated protein 1 chr20 GO:0031490 Not Cancer Driver No 25 0.049 359 12 0.033 0
JMJD1C JMJD1C Q15652 Probable JmjC domain-containing histone demethylation protein 2C chr10 GO:0031490 Not Cancer Driver No 305 0.12 1640 200 0.122 0
KDM3A_ENST00000312912 KDM3A Q9Y4C1 Lysine-specific demethylase 3A chr2 GO:0031490 Not Cancer Driver No 136 0.103 461 47 0.102 0
KDM3B KDM3B Q7LBC6 Lysine-specific demethylase 3B chr5 GO:0031490 Compendium Yes 221 0.125 943 114 0.121 7
KDM4D_ENST00000610872 KDM4D Q6B0I6 Lysine-specific demethylase 4D chr11 GO:0031490 Not Cancer Driver No 78 0.149 215 33 0.153 0
KDM5A KDM5A P29375 Lysine-specific demethylase 5A chr12 GO:0031490 Census, Compendium Yes 220 0.13 503 66 0.131 0
KDM6A KDM6A O15550 Lysine-specific demethylase 6A chrX GO:0031490 Census, Compendium Yes 173 0.123 648 71 0.11 0
KDM6B_ENST00000448097 KDM6B O15054 Lysine-specific demethylase 6B chr17 GO:0031490 Not Cancer Driver No 189 0.115 1278 142 0.111 2
LEMD2_ENST00000614475 LEMD2 Q8NC56 LEM domain-containing protein 2 chr6 GO:0031490 Not Cancer Driver No 44 0.087 211 4 0.019 2
LEMD3 LEMD3 Q9Y2U8 Inner nuclear membrane protein Man1 chr12 GO:0031490 Not Cancer Driver No 78 0.086 509 33 0.065 0
MBD2 MBD2 Q9UBB5 Methyl-CpG-binding domain protein 2 chr18 GO:0031490 Not Cancer Driver No 26 0.063 384 25 0.065 0
MBD3 MBD3 O95983 Methyl-CpG-binding domain protein 3 chr19 GO:0031490 Not Cancer Driver No 50 0.172 246 46 0.187 0
MTA2 MTA2 O94776 Metastasis-associated protein MTA2 chr11 GO:0031490 Not Cancer Driver No 78 0.117 283 32 0.113 0
MYOD1 MYOD1 P15172 Myoblast determination protein 1 chr11 GO:0031490 Census Yes 45 0.141 246 33 0.134 0
MYOG MYOG P15173 Myogenin chr1 GO:0031490 Not Cancer Driver No 36 0.161 132 20 0.152 0
NEUROG3 NEUROG3 Q9Y4Z2 Neurogenin-3 chr10 GO:0031490 Not Cancer Driver No 53 0.248 156 34 0.218 2
NKAP NKAP Q8N5F7 NF-kappa-B-activating protein chrX GO:0031490 Not Cancer Driver No 80 0.193 409 77 0.188 3
NOTCH1 NOTCH1 P46531 Neurogenic locus notch homolog protein 1 chr9 GO:0031490 Census, Compendium Yes 363 0.142 686 87 0.127 3
PER1 PER1 O15534 Period circadian protein homolog 1 chr17 GO:0031490 Census Yes 160 0.124 948 116 0.122 0
POLE3 POLE3 Q9NRF9 DNA polymerase epsilon subunit 3 chr9 GO:0031490 Not Cancer Driver No 11 0.075 117 9 0.077 0
PPARGC1A PPARGC1A Q9UBK2 Peroxisome proliferator-activated receptor gamma coactivator 1-alpha chr4 GO:0031490 Not Cancer Driver No 181 0.227 609 148 0.243 0
PRDM14 PRDM14 Q9GZV8 PR domain zinc finger protein 14 chr8 GO:0031490 Not Cancer Driver No 122 0.214 179 37 0.207 0
RARA RARA P10276 Retinoic acid receptor alpha chr17 GO:0031490 Census, Compendium Yes 70 0.152 167 14 0.084 0
RBBP4 RBBP4 Q09028 Histone-binding protein RBBP4 chr1 GO:0031490 Not Cancer Driver No 53 0.125 169 23 0.136 0
RCC1_ENST00000373833 RCC1 P18754 Regulator of chromosome condensation chr1 GO:0031490 Not Cancer Driver No 54 0.128 143 15 0.105 0
RELA RELA Q04206 Transcription factor p65 chr11 GO:0031490 Compendium Yes 75 0.136 400 48 0.12 0
REPIN1_ENST00000397281 REPIN1 Q9BWE0 Replication initiator 1 chr7 GO:0031490 Not Cancer Driver No 62 0.109 259 28 0.108 0
RUVBL2 RUVBL2 Q9Y230 RuvB-like 2 chr19 GO:0031490 Not Cancer Driver No 62 0.134 100 13 0.13 0
SBNO1 SBNO1 A3KN83 Protein strawberry notch homolog 1 chr12 GO:0031490 Not Cancer Driver No 189 0.136 569 68 0.12 0
SBNO2 SBNO2 Q9Y2G9 Protein strawberry notch homolog 2 chr19 GO:0031490 Not Cancer Driver No 108 0.079 456 29 0.064 0
SMAD3 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 GO:0031490 Census, Compendium Yes 97 0.228 111 19 0.171 5
SMARCA4 SMARCA4 P51532 Transcription activator BRG1 chr19 GO:0031490 Census, Compendium Yes 349 0.212 1072 195 0.182 5
SMARCB1_ENST00000644036 SMARCB1 Q12824 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 chr22 GO:0031490 Census, Compendium Yes 64 0.166 141 35 0.248 3
SMARCC1 SMARCC1 Q92922 SWI/SNF complex subunit SMARCC1 chr3 GO:0031490 Not Cancer Driver No 125 0.113 720 81 0.113 0
SMARCC2_ENST00000267064 SMARCC2 Q8TAQ2 SWI/SNF complex subunit SMARCC2 chr12 GO:0031490 Not Cancer Driver No 175 0.144 876 133 0.152 4
SMARCD2 SMARCD2 Q92925 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 chr17 GO:0031490 Not Cancer Driver No 58 0.109 251 26 0.104 0
SMARCE1 SMARCE1 Q969G3 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 chr17 GO:0031490 Census Yes 47 0.114 332 36 0.108 2
SRF SRF P11831 Serum response factor chr6 GO:0031490 Not Cancer Driver No 44 0.087 443 42 0.095 0
STAT3 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 GO:0031490 Census, Compendium Yes 110 0.143 152 15 0.099 19
SUZ12 SUZ12 Q15022 Polycomb protein SUZ12 chr17 GO:0031490 Census, Compendium Yes 83 0.112 483 46 0.095 3
THRA THRA P10827 Thyroid hormone receptor alpha chr17 GO:0031490 Not Cancer Driver No 69 0.141 207 30 0.145 2
THRB_ENST00000415021 THRB P10828 Thyroid hormone receptor beta chr3 GO:0031490 Not Cancer Driver No 87 0.189 113 28 0.248 33
TOX TOX O94900 Thymocyte selection-associated high mobility group box protein TOX chr8 GO:0031490 Not Cancer Driver No 112 0.213 494 108 0.219 0
TOX2_ENST00000358131 TOX2 Q96NM4 TOX high mobility group box family member 2 chr20 GO:0031490 Not Cancer Driver No 131 0.268 392 108 0.276 0
TOX3 TOX3 O15405 TOX high mobility group box family member 3 chr16 GO:0031490 Not Cancer Driver No 85 0.148 485 72 0.148 0
TOX4_ENST00000448790 TOX4 O94842 TOX high mobility group box family member 4 chr14 GO:0031490 Not Cancer Driver No 69 0.111 562 62 0.11 0
UTY_ENST00000331397 UTY O14607 Histone demethylase UTY chrY GO:0031490 Not Cancer Driver No 38 0.028 564 21 0.037 0
VAX1 VAX1 Q5SQQ9 Ventral anterior homeobox 1 chr10 GO:0031490 Not Cancer Driver No 36 0.108 234 25 0.107 1
VAX2 VAX2 Q9UIW0 Ventral anterior homeobox 2 chr2 GO:0031490 Not Cancer Driver No 34 0.117 210 22 0.105 0
WBP2NL WBP2NL Q6ICG8 Postacrosomal sheath WW domain-binding protein chr22 GO:0031490 Not Cancer Driver No 46 0.149 153 27 0.176 0
WBP2_ENST00000254806 WBP2 Q969T9 WW domain-binding protein 2 chr17 GO:0031490 Not Cancer Driver No 26 0.1 102 6 0.059 1
ZFX_ENST00000304543 ZFX P17010 Zinc finger X-chromosomal protein chrX GO:0031490 Compendium Yes 95 0.118 370 34 0.092 0
ZIC2 ZIC2 O95409 Zinc finger protein ZIC 2 chr13 GO:0031490 Not Cancer Driver No 40 0.075 387 23 0.059 21
ZNF276 ZNF276 Q8N554 Zinc finger protein 276 chr16 GO:0031490 Not Cancer Driver No 74 0.121 349 34 0.097 0