Total number of protein in "GO:0031397" GO term: 82
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABL1_ENST00000318560 | ABL1 | P00519 | Tyrosine-protein kinase ABL1 | chr9 | GO:0031397 | Census, Compendium | Yes | 139 | 0.123 | 604 | 73 | 0.121 | 2 |
| ADGRB1_ENST00000323289 | ADGRB1 | O14514 | Adhesion G protein-coupled receptor B1 | chr8 | GO:0031397 | Compendium | Yes | 213 | 0.134 | 485 | 47 | 0.097 | 0 |
| AKT1_ENST00000349310 | AKT1 | P31749 | RAC-alpha serine/threonine-protein kinase | chr14 | GO:0031397 | Census, Compendium | Yes | 108 | 0.225 | 158 | 24 | 0.152 | 4 |
| ARRB1 | ARRB1 | P49407 | Beta-arrestin-1 | chr11 | GO:0031397 | Not Cancer Driver | No | 49 | 0.117 | 154 | 13 | 0.084 | 0 |
| ARRB2_ENST00000269260 | ARRB2 | P32121 | Beta-arrestin-2 | chr17 | GO:0031397 | Not Cancer Driver | No | 46 | 0.112 | 122 | 22 | 0.18 | 0 |
| ATG5_ENST00000343245 | ATG5 | Q9H1Y0 | Autophagy protein 5 | chr6 | GO:0031397 | Not Cancer Driver | No | 40 | 0.145 | 25 | 6 | 0.24 | 1 |
| BAG2 | BAG2 | O95816 | BAG family molecular chaperone regulator 2 | chr6 | GO:0031397 | Not Cancer Driver | No | 17 | 0.081 | 112 | 9 | 0.08 | 0 |
| BAG5_ENST00000299204 | BAG5 | Q9UL15 | BAG family molecular chaperone regulator 5 | chr14 | GO:0031397 | Not Cancer Driver | No | 37 | 0.083 | 63 | 7 | 0.111 | 0 |
| BUB1B | BUB1B | O60566 | Mitotic checkpoint serine/threonine-protein kinase BUB1 beta | chr15 | GO:0031397 | Census | Yes | 96 | 0.091 | 480 | 35 | 0.073 | 7 |
| BUB3 | BUB3 | O43684 | Mitotic checkpoint protein BUB3 | chr10 | GO:0031397 | Not Cancer Driver | No | 46 | 0.14 | 60 | 6 | 0.1 | 0 |
| CAMLG | CAMLG | P49069 | Guided entry of tail-anchored proteins factor CAMLG | chr5 | GO:0031397 | Not Cancer Driver | No | 32 | 0.108 | 157 | 16 | 0.102 | 0 |
| CAV1 | CAV1 | Q03135 | Caveolin-1 | chr7 | GO:0031397 | Not Cancer Driver | No | 30 | 0.169 | 2 | 0 | 0.0 | 0 |
| CDC20 | CDC20 | Q12834 | Cell division cycle protein 20 homolog | chr1 | GO:0031397 | Not Cancer Driver | No | 44 | 0.088 | 198 | 15 | 0.076 | 0 |
| CDK5 | CDK5 | Q00535 | Cyclin-dependent kinase 5 | chr7 | GO:0031397 | Not Cancer Driver | No | 48 | 0.164 | 5 | 1 | 0.2 | 0 |
| CHP1 | CHP1 | Q99653 | Calcineurin B homologous protein 1 | chr15 | GO:0031397 | Not Cancer Driver | No | 27 | 0.138 | 70 | 12 | 0.171 | 0 |
| CRY1 | CRY1 | Q16526 | Cryptochrome-1 | chr12 | GO:0031397 | Not Cancer Driver | No | 76 | 0.13 | 91 | 5 | 0.055 | 0 |
| DNAJA1 | DNAJA1 | P31689 | DnaJ homolog subfamily A member 1 | chr9 | GO:0031397 | Not Cancer Driver | No | 37 | 0.093 | 153 | 16 | 0.105 | 0 |
| DTX3L | DTX3L | Q8TDB6 | E3 ubiquitin-protein ligase DTX3L | chr3 | GO:0031397 | Not Cancer Driver | No | 86 | 0.116 | 260 | 24 | 0.092 | 0 |
| FBXO5 | FBXO5 | Q9UKT4 | F-box only protein 5 | chr6 | GO:0031397 | Not Cancer Driver | No | 48 | 0.107 | 113 | 13 | 0.115 | 0 |
| FYN | FYN | P06241 | Tyrosine-protein kinase Fyn | chr6 | GO:0031397 | Not Cancer Driver | No | 92 | 0.171 | 70 | 13 | 0.186 | 0 |
| GCLC | GCLC | P48506 | Glutamate--cysteine ligase catalytic subunit | chr6 | GO:0031397 | Not Cancer Driver | No | 73 | 0.115 | 167 | 18 | 0.108 | 3 |
| GLMN | GLMN | Q92990 | Glomulin | chr1 | GO:0031397 | Not Cancer Driver | No | 49 | 0.082 | 37 | 6 | 0.162 | 0 |
| GNL3L_ENST00000360845 | GNL3L | Q9NVN8 | Guanine nucleotide-binding protein-like 3-like protein | chrX | GO:0031397 | Not Cancer Driver | No | 120 | 0.206 | 242 | 43 | 0.178 | 0 |
| GPS2 | GPS2 | Q13227 | G protein pathway suppressor 2 | chr17 | GO:0031397 | Not Cancer Driver | No | 29 | 0.089 | 319 | 26 | 0.082 | 0 |
| GTPBP4 | GTPBP4 | Q9BZE4 | GTP-binding protein 4 | chr10 | GO:0031397 | Not Cancer Driver | No | 79 | 0.125 | 232 | 34 | 0.147 | 0 |
| HDAC8 | HDAC8 | Q9BY41 | Histone deacetylase 8 | chrX | GO:0031397 | Not Cancer Driver | No | 54 | 0.143 | 32 | 4 | 0.125 | 4 |
| HSPA1A | HSPA1A | P0DMV8 | Heat shock 70 kDa protein 1A | chr6 | GO:0031397 | Not Cancer Driver | No | 24 | 0.037 | 200 | 13 | 0.065 | 0 |
| HSPA1B | HSPA1B | P0DMV9 | Heat shock 70 kDa protein 1B | chr6 | GO:0031397 | Not Cancer Driver | No | 15 | 0.023 | 200 | 5 | 0.025 | 0 |
| ISG15 | ISG15 | P05161 | Ubiquitin-like protein ISG15 | chr1 | GO:0031397 | Not Cancer Driver | No | 12 | 0.073 | 24 | 2 | 0.083 | 0 |
| IVNS1ABP | IVNS1ABP | Q9Y6Y0 | Influenza virus NS1A-binding protein | chr1 | GO:0031397 | Not Cancer Driver | No | 85 | 0.132 | 90 | 12 | 0.133 | 0 |
| KLHL40 | KLHL40 | Q2TBA0 | Kelch-like protein 40 | chr3 | GO:0031397 | Not Cancer Driver | No | 108 | 0.174 | 44 | 8 | 0.182 | 13 |
| LIMK1 | LIMK1 | P53667 | LIM domain kinase 1 | chr7 | GO:0031397 | Not Cancer Driver | No | 110 | 0.17 | 170 | 30 | 0.176 | 0 |
| MAD2L1 | MAD2L1 | Q13257 | Mitotic spindle assembly checkpoint protein MAD2A | chr4 | GO:0031397 | Not Cancer Driver | No | 26 | 0.127 | 12 | 1 | 0.083 | 0 |
| MAD2L2 | MAD2L2 | Q9UI95 | Mitotic spindle assembly checkpoint protein MAD2B | chr1 | GO:0031397 | Not Cancer Driver | No | 22 | 0.104 | 0 | 0 | 0.0 | 1 |
| MARCH7 | MARCHF7 | Q9H992 | E3 ubiquitin-protein ligase MARCHF7 | chr2 | GO:0031397 | Not Cancer Driver | No | 85 | 0.121 | 550 | 68 | 0.124 | 0 |
| MINAR1 | MINAR1 | Q9UPX6 | Major intrinsically disordered Notch2-binding receptor 1 | chr15 | GO:0031397 | Not Cancer Driver | No | 171 | 0.187 | 584 | 104 | 0.178 | 0 |
| N4BP1 | N4BP1 | O75113 | NEDD4-binding protein 1 | chr16 | GO:0031397 | Not Cancer Driver | No | 108 | 0.121 | 432 | 58 | 0.134 | 0 |
| NXN | NXN | Q6DKJ4 | Nucleoredoxin | chr17 | GO:0031397 | Not Cancer Driver | No | 58 | 0.133 | 37 | 2 | 0.054 | 0 |
| OGT | OGT | O15294 | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | chrX | GO:0031397 | Not Cancer Driver | No | 156 | 0.149 | 89 | 16 | 0.18 | 2 |
| OTUB1_ENST00000428192 | OTUB1 | Q96FW1 | Ubiquitin thioesterase OTUB1 | chr11 | GO:0031397 | Not Cancer Driver | No | 31 | 0.114 | 33 | 2 | 0.061 | 0 |
| OTUB2 | OTUB2 | Q96DC9 | Ubiquitin thioesterase OTUB2 | chr14 | GO:0031397 | Not Cancer Driver | No | 30 | 0.128 | 0 | 0 | 0.0 | 0 |
| PARK7_ENST00000377488 | PARK7 | Q99497 | Parkinson disease protein 7 | chr1 | GO:0031397 | Not Cancer Driver | No | 11 | 0.058 | 30 | 0 | 0.0 | 5 |
| PARP10_ENST00000313028 | PARP10 | Q53GL7 | Protein mono-ADP-ribosyltransferase PARP10 | chr8 | GO:0031397 | Not Cancer Driver | No | 122 | 0.119 | 552 | 68 | 0.123 | 0 |
| PER2 | PER2 | O15055 | Period circadian protein homolog 2 | chr2 | GO:0031397 | Not Cancer Driver | No | 166 | 0.132 | 782 | 101 | 0.129 | 1 |
| PINX1 | PINX1 | Q96BK5 | PIN2/TERF1-interacting telomerase inhibitor 1 | chr8 | GO:0031397 | Not Cancer Driver | No | 66 | 0.201 | 328 | 66 | 0.201 | 0 |
| PLAA | PLAA | Q9Y263 | Phospholipase A-2-activating protein | chr9 | GO:0031397 | Not Cancer Driver | No | 78 | 0.098 | 150 | 14 | 0.093 | 2 |
| PPIA | PPIA | P62937 | Peptidyl-prolyl cis-trans isomerase A | chr7 | GO:0031397 | Not Cancer Driver | No | 11 | 0.067 | 24 | 3 | 0.125 | 0 |
| PRKCE | PRKCE | Q02156 | Protein kinase C epsilon type | chr2 | GO:0031397 | Not Cancer Driver | No | 107 | 0.145 | 170 | 26 | 0.153 | 0 |
| PRKCG | PRKCG | P05129 | Protein kinase C gamma type | chr19 | GO:0031397 | Not Cancer Driver | No | 172 | 0.247 | 151 | 43 | 0.285 | 5 |
| PRMT3 | PRMT3 | O60678 | Protein arginine N-methyltransferase 3 | chr11 | GO:0031397 | Not Cancer Driver | No | 68 | 0.128 | 52 | 9 | 0.173 | 0 |
| PRR7_ENST00000502922 | PRR7 | Q8TB68 | Proline-rich protein 7 | chr5 | GO:0031397 | Not Cancer Driver | No | 10 | 0.036 | 199 | 6 | 0.03 | 0 |
| PSEN1 | PSEN1 | P49768 | Presenilin-1 | chr14 | GO:0031397 | Not Cancer Driver | No | 61 | 0.131 | 134 | 21 | 0.157 | 96 |
| RPL11 | RPL11 | P62913 | 60S ribosomal protein L11 | chr1 | GO:0031397 | Not Cancer Driver | No | 27 | 0.152 | 12 | 1 | 0.083 | 1 |
| RPL23_ENST00000394332 | RPL23 | P62829 | 60S ribosomal protein L23 | chr17 | GO:0031397 | Not Cancer Driver | No | 14 | 0.1 | 29 | 4 | 0.138 | 0 |
| RPL37 | RPL37 | P61927 | 60S ribosomal protein L37 | chr5 | GO:0031397 | Not Cancer Driver | No | 12 | 0.124 | 83 | 10 | 0.12 | 0 |
| RPL5_ENST00000370321 | RPL5 | P46777 | 60S ribosomal protein L5 | chr1 | GO:0031397 | Census | Yes | 57 | 0.192 | 96 | 17 | 0.177 | 2 |
| RPS15_ENST00000592588 | RPS15 | P62841 | 40S ribosomal protein S15 | chr19 | GO:0031397 | Not Cancer Driver | No | 13 | 0.09 | 59 | 7 | 0.119 | 0 |
| RPS20_ENST00000521262 | RPS20 | P60866 | 40S ribosomal protein S20 | chr8 | GO:0031397 | Not Cancer Driver | No | 18 | 0.151 | 53 | 8 | 0.151 | 0 |
| RPS3_ENST00000527446 | RPS3 | P23396 | 40S ribosomal protein S3 | chr11 | GO:0031397 | Not Cancer Driver | No | 22 | 0.091 | 48 | 4 | 0.083 | 0 |
| RPS7_ENST00000645674 | RPS7 | P62081 | 40S ribosomal protein S7 | chr2 | GO:0031397 | Not Cancer Driver | No | 29 | 0.149 | 39 | 7 | 0.179 | 0 |
| SENP2 | SENP2 | Q9HC62 | Sentrin-specific protease 2 | chr3 | GO:0031397 | Not Cancer Driver | No | 73 | 0.124 | 285 | 38 | 0.133 | 0 |
| SH3RF2 | SH3RF2 | Q8TEC5 | E3 ubiquitin-protein ligase SH3RF2 | chr5 | GO:0031397 | Not Cancer Driver | No | 151 | 0.207 | 455 | 101 | 0.222 | 0 |
| SIRT7 | SIRT7 | Q9NRC8 | NAD-dependent protein deacetylase sirtuin-7 | chr17 | GO:0031397 | Not Cancer Driver | No | 48 | 0.12 | 163 | 15 | 0.092 | 0 |
| SMAD7 | SMAD7 | O15105 | Mothers against decapentaplegic homolog 7 | chr18 | GO:0031397 | Not Cancer Driver | No | 40 | 0.094 | 139 | 0 | 0.0 | 0 |
| SOX4 | SOX4 | Q06945 | Transcription factor SOX-4 | chr6 | GO:0031397 | Not Cancer Driver | No | 28 | 0.059 | 400 | 24 | 0.06 | 4 |
| SPOPL | SPOPL | Q6IQ16 | Speckle-type POZ protein-like | chr2 | GO:0031397 | Not Cancer Driver | No | 87 | 0.222 | 40 | 14 | 0.35 | 0 |
| SPRY2 | SPRY2 | O43597 | Protein sprouty homolog 2 | chr13 | GO:0031397 | Not Cancer Driver | No | 46 | 0.146 | 169 | 29 | 0.172 | 1 |
| SQSTM1 | SQSTM1 | Q13501 | Sequestosome-1 | chr5 | GO:0031397 | Not Cancer Driver | No | 54 | 0.123 | 267 | 32 | 0.12 | 30 |
| SVBP_ENST00000372522 | SVBP | Q8N300 | Small vasohibin-binding protein | chr1 | GO:0031397 | Not Cancer Driver | No | 7 | 0.106 | 66 | 7 | 0.106 | 0 |
| TAF1_ENST00000373790 | TAF1 | P21675 | Transcription initiation factor TFIID subunit 1 | chrX | GO:0031397 | Not Cancer Driver | No | 379 | 0.202 | 1152 | 219 | 0.19 | 5 |
| TNFAIP3 | TNFAIP3 | P21580 | Tumor necrosis factor alpha-induced protein 3 | chr6 | GO:0031397 | Census, Compendium | Yes | 98 | 0.124 | 231 | 33 | 0.143 | 1 |
| TRIM44 | TRIM44 | Q96DX7 | Tripartite motif-containing protein 44 | chr11 | GO:0031397 | Not Cancer Driver | No | 40 | 0.116 | 272 | 33 | 0.121 | 1 |
| TRIP12_ENST00000283943 | TRIP12 | Q14669 | E3 ubiquitin-protein ligase TRIP12 | chr2 | GO:0031397 | Not Cancer Driver | No | 224 | 0.112 | 845 | 117 | 0.138 | 4 |
| TSPO_ENST00000329563 | TSPO | P30536 | Translocator protein | chr22 | GO:0031397 | Not Cancer Driver | No | 5 | 0.03 | 1 | 0 | 0.0 | 0 |
| TTC36 | TTC36 | A6NLP5 | Tetratricopeptide repeat protein 36 | chr11 | GO:0031397 | Not Cancer Driver | No | 13 | 0.069 | 98 | 12 | 0.122 | 0 |
| U2AF2 | U2AF2 | P26368 | Splicing factor U2AF 65 kDa subunit | chr19 | GO:0031397 | Compendium | Yes | 78 | 0.164 | 191 | 28 | 0.147 | 0 |
| UBR5 | UBR5 | O95071 | E3 ubiquitin-protein ligase UBR5 | chr8 | GO:0031397 | Census, Compendium | Yes | 340 | 0.121 | 1296 | 162 | 0.125 | 0 |
| UBXN1_ENST00000301935 | UBXN1 | Q04323 | UBX domain-containing protein 1 | chr11 | GO:0031397 | Not Cancer Driver | No | 35 | 0.118 | 271 | 33 | 0.122 | 0 |
| UFL1 | UFL1 | O94874 | E3 UFM1-protein ligase 1 | chr6 | GO:0031397 | Not Cancer Driver | No | 109 | 0.137 | 141 | 24 | 0.17 | 0 |
| USP4 | USP4 | Q13107 | Ubiquitin carboxyl-terminal hydrolase 4 | chr3 | GO:0031397 | Not Cancer Driver | No | 102 | 0.106 | 286 | 22 | 0.077 | 0 |
| USP44_ENST00000537435 | USP44 | Q9H0E7 | Ubiquitin carboxyl-terminal hydrolase 44 | chr12 | GO:0031397 | Census, Compendium | Yes | 94 | 0.132 | 114 | 14 | 0.123 | 0 |
| VPS28_ENST00000292510 | VPS28 | Q9UK41 | Vacuolar protein sorting-associated protein 28 homolog | chr8 | GO:0031397 | Not Cancer Driver | No | 28 | 0.127 | 31 | 5 | 0.161 | 0 |