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Total number of protein in "GO:0031330" GO term:  132

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
A1CF_ENST00000373993 A1CF Q9NQ94 APOBEC1 complementation factor chr10 GO:0031330 Census Yes 150 0.253 63 20 0.317 0
ACACB_ENST00000377848 ACACB O00763 Acetyl-CoA carboxylase 2 chr12 GO:0031330 Not Cancer Driver No 388 0.158 342 62 0.181 0
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:0031330 Census, Compendium Yes 108 0.225 158 24 0.152 4
ANGEL2 ANGEL2 Q5VTE6 Protein angel homolog 2 chr1 GO:0031330 Not Cancer Driver No 56 0.103 48 6 0.125 0
ANXA2_ENST00000396024 ANXA2 P07355 Annexin A2 chr15 GO:0031330 Not Cancer Driver No 49 0.145 20 4 0.2 0
APOBEC1 APOBEC1 P41238 C->U-editing enzyme APOBEC-1 chr12 GO:0031330 Not Cancer Driver No 62 0.263 13 1 0.077 0
APOC1_ENST00000588802 APOC1 P02654 Apolipoprotein C-I chr19 GO:0031330 Not Cancer Driver No 12 0.145 9 1 0.111 0
APOC3 APOC3 P02656 Apolipoprotein C-III chr11 GO:0031330 Not Cancer Driver No 14 0.141 12 2 0.167 1
AQP11 AQP11 Q8NBQ7 Aquaporin-11 chr11 GO:0031330 Not Cancer Driver No 23 0.085 0 0 0.0 0
ATG7 ATG7 O95352 Ubiquitin-like modifier-activating enzyme ATG7 chr3 GO:0031330 Compendium Yes 77 0.11 53 8 0.151 6
ATP13A2 ATP13A2 Q9NQ11 Polyamine-transporting ATPase 13A2 chr1 GO:0031330 Not Cancer Driver No 152 0.129 121 10 0.083 9
BECN1_ENST00000590099 BECN1 Q14457 Beclin-1 chr17 GO:0031330 Not Cancer Driver No 45 0.1 190 19 0.1 0
BOLL_ENST00000392296 BOLL Q8N9W6 Protein boule-like chr2 GO:0031330 Not Cancer Driver No 59 0.208 78 22 0.282 0
CHMP4A_ENST00000609024 CHMP4A Q9BY43 Charged multivesicular body protein 4a chr14 GO:0031330 Not Cancer Driver No 24 0.108 204 23 0.113 0
CHMP4B CHMP4B Q9H444 Charged multivesicular body protein 4b chr20 GO:0031330 Not Cancer Driver No 25 0.112 201 22 0.109 2
CLEC16A CLEC16A Q2KHT3 Protein CLEC16A chr16 GO:0031330 Not Cancer Driver No 149 0.142 374 53 0.142 0
CNR1_ENST00000549890 CNR1 P21554 Cannabinoid receptor 1 chr6 GO:0031330 Not Cancer Driver No 129 0.273 9 1 0.111 0
CSDE1_ENST00000358528 CSDE1 O75534 Cold shock domain-containing protein E1 chr1 GO:0031330 Not Cancer Driver No 118 0.148 204 29 0.142 0
CSNK2A1_ENST00000400217 CSNK2A1 P68400 Casein kinase II subunit alpha chr20 GO:0031330 Not Cancer Driver No 71 0.182 75 8 0.107 4
CSNK2A2 CSNK2A2 P19784 Casein kinase II subunit alpha' chr16 GO:0031330 Not Cancer Driver No 43 0.123 13 1 0.077 0
CST3_ENST00000376925 CST3 P01034 Cystatin-C chr20 GO:0031330 Not Cancer Driver No 17 0.116 31 1 0.032 2
CTSA_ENST00000372459 CTSA P10619 Lysosomal protective protein chr20 GO:0031330 Not Cancer Driver No 59 0.123 14 1 0.071 12
DAZ2_ENST00000382424 DAZ2 Q13117 Deleted in azoospermia protein 2 chrY GO:0031330 Not Cancer Driver No 1 0.002 72 0 0.0 0
DAZL_ENST00000399444 DAZL Q92904 Deleted in azoospermia-like chr3 GO:0031330 Not Cancer Driver No 28 0.095 128 12 0.094 0
DFFA DFFA O00273 DNA fragmentation factor subunit alpha chr1 GO:0031330 Not Cancer Driver No 47 0.142 113 18 0.159 0
DHX34 DHX34 Q14147 Probable ATP-dependent RNA helicase DHX34 chr19 GO:0031330 Not Cancer Driver No 175 0.153 326 41 0.126 0
DHX36 DHX36 Q9H2U1 ATP-dependent DNA/RNA helicase DHX36 chr3 GO:0031330 Not Cancer Driver No 159 0.158 222 39 0.176 0
DHX9 DHX9 Q08211 ATP-dependent RNA helicase A chr1 GO:0031330 Compendium Yes 182 0.143 331 42 0.127 0
DKC1 DKC1 O60832 H/ACA ribonucleoprotein complex subunit DKC1 chrX GO:0031330 Not Cancer Driver No 62 0.121 145 29 0.2 24
EHMT2_ENST00000375537 EHMT2 Q96KQ7 Histone-lysine N-methyltransferase EHMT2 chr6 GO:0031330 Not Cancer Driver No 142 0.117 585 71 0.121 0
EIF4ENIF1 EIF4ENIF1 Q9NRA8 Eukaryotic translation initiation factor 4E transporter chr22 GO:0031330 Not Cancer Driver No 116 0.118 899 101 0.112 0
ELAVL1 ELAVL1 Q15717 ELAV-like protein 1 chr19 GO:0031330 Not Cancer Driver No 69 0.212 43 5 0.116 0
ELAVL4_ENST00000371821 ELAVL4 P26378 ELAV-like protein 4 chr1 GO:0031330 Not Cancer Driver No 118 0.306 117 34 0.291 0
ETFBKMT_ENST00000412352 ETFBKMT Q8IXQ9 Electron transfer flavoprotein beta subunit lysine methyltransferase chr12 GO:0031330 Not Cancer Driver No 25 0.095 0 0 0.0 0
FEZ1 FEZ1 Q99689 Fasciculation and elongation protein zeta-1 chr11 GO:0031330 Not Cancer Driver No 66 0.168 277 49 0.177 0
FEZ2_ENST00000405912 FEZ2 Q9UHY8 Fasciculation and elongation protein zeta-2 chr2 GO:0031330 Not Cancer Driver No 37 0.105 245 29 0.118 0
FMR1 FMR1 Q06787 Synaptic functional regulator FMR1 chrX GO:0031330 Not Cancer Driver No 124 0.196 327 70 0.214 3
FURIN_ENST00000610579 FURIN P09958 Furin chr15 GO:0031330 Not Cancer Driver No 93 0.117 283 35 0.124 0
GPLD1 GPLD1 P80108 Phosphatidylinositol-glycan-specific phospholipase D chr6 GO:0031330 Not Cancer Driver No 153 0.182 36 9 0.25 0
GSK3A GSK3A P49840 Glycogen synthase kinase-3 alpha chr19 GO:0031330 Not Cancer Driver No 55 0.114 180 8 0.044 0
HFE HFE Q30201 Hereditary hemochromatosis protein chr6 GO:0031330 Not Cancer Driver No 55 0.158 27 2 0.074 11
HIPK2 HIPK2 Q9H2X6 Homeodomain-interacting protein kinase 2 chr7 GO:0031330 Not Cancer Driver No 154 0.129 686 96 0.14 0
HNRNPA0 HNRNPA0 Q13151 Heterogeneous nuclear ribonucleoprotein A0 chr5 GO:0031330 Not Cancer Driver No 25 0.082 172 14 0.081 0
HNRNPAB HNRNPAB Q99729 Heterogeneous nuclear ribonucleoprotein A/B chr5 GO:0031330 Not Cancer Driver No 31 0.093 202 11 0.054 0
HNRNPC_ENST00000420743 HNRNPC P07910 Heterogeneous nuclear ribonucleoproteins C1/C2 chr14 GO:0031330 Not Cancer Driver No 42 0.137 227 35 0.154 0
HNRNPD HNRNPD Q14103 Heterogeneous nuclear ribonucleoprotein D0 chr4 GO:0031330 Not Cancer Driver No 39 0.11 206 19 0.092 0
HNRNPU HNRNPU Q00839 Heterogeneous nuclear ribonucleoprotein U chr1 GO:0031330 Not Cancer Driver No 77 0.093 504 45 0.089 0
HP HP P00738 Haptoglobin chr16 GO:0031330 Not Cancer Driver No 39 0.096 57 2 0.035 1
IGF2BP1 IGF2BP1 Q9NZI8 Insulin-like growth factor 2 mRNA-binding protein 1 chr17 GO:0031330 Not Cancer Driver No 141 0.244 298 80 0.268 0
IL10 IL10 P22301 Interleukin-10 chr1 GO:0031330 Not Cancer Driver No 19 0.107 23 1 0.043 0
INS INS P01308 Insulin chr11 GO:0031330 Not Cancer Driver No 15 0.136 5 1 0.2 22
LAPTM4B_ENST00000619747 LAPTM4B Q86VI4 Lysosomal-associated transmembrane protein 4B chr8 GO:0031330 Not Cancer Driver No 24 0.076 73 5 0.068 0
LRIG2 LRIG2 O94898 Leucine-rich repeats and immunoglobulin-like domains protein 2 chr1 GO:0031330 Not Cancer Driver No 131 0.123 231 30 0.13 0
LRPPRC LRPPRC P42704 Leucine-rich PPR motif-containing protein, mitochondrial chr2 GO:0031330 Not Cancer Driver No 131 0.094 18 2 0.111 1
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 GO:0031330 Not Cancer Driver No 519 0.205 90 17 0.189 23
MAPK14_ENST00000229794 MAPK14 Q16539 Mitogen-activated protein kinase 14 chr6 GO:0031330 Not Cancer Driver No 39 0.108 25 1 0.04 0
MAPKAPK2 MAPKAPK2 P49137 MAP kinase-activated protein kinase 2 chr1 GO:0031330 Not Cancer Driver No 43 0.107 92 5 0.054 0
MFSD2A MFSD2A Q8NA29 Sodium-dependent lysophosphatidylcholine symporter 1 chr1 GO:0031330 Not Cancer Driver No 61 0.112 36 4 0.111 7
MGAT3 MGAT3 Q09327 Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase chr22 GO:0031330 Not Cancer Driver No 105 0.197 130 27 0.208 0
MT3 MT3 P25713 Metallothionein-3 chr16 GO:0031330 Not Cancer Driver No 7 0.103 0 0 0.0 0
MTM1 MTM1 Q13496 Myotubularin chrX GO:0031330 Not Cancer Driver No 112 0.186 79 9 0.114 57
MTMR2 MTMR2 Q13614 Myotubularin-related protein 2 chr11 GO:0031330 Not Cancer Driver No 70 0.109 140 16 0.114 1
MYD88_ENST00000396334 MYD88 Q99836 Myeloid differentiation primary response protein MyD88 chr3 GO:0031330 Census, Compendium Yes 37 0.125 47 1 0.021 2
NAF1 NAF1 Q96HR8 H/ACA ribonucleoprotein complex non-core subunit NAF1 chr4 GO:0031330 Not Cancer Driver No 61 0.123 386 44 0.114 0
NBAS NBAS A2RRP1 NBAS subunit of NRZ tethering complex chr2 GO:0031330 Not Cancer Driver No 365 0.154 246 41 0.167 5
NRDE2 NRDE2 Q9H7Z3 Nuclear exosome regulator NRDE2 chr14 GO:0031330 Not Cancer Driver No 135 0.116 373 50 0.134 0
NSUN2 NSUN2 Q08J23 RNA cytosine C(5)-methyltransferase NSUN2 chr5 GO:0031330 Not Cancer Driver No 112 0.146 221 21 0.095 1
NUPR1_ENST00000324873 NUPR1 O60356 Nuclear protein 1 chr16 GO:0031330 Not Cancer Driver No 10 0.122 82 10 0.122 0
PABPC1 PABPC1 P11940 Polyadenylate-binding protein 1 chr8 GO:0031330 Census, Compendium Yes 100 0.157 317 55 0.174 0
PAIP1 PAIP1 Q9H074 Polyadenylate-binding protein-interacting protein 1 chr5 GO:0031330 Not Cancer Driver No 67 0.14 259 36 0.139 0
PARN PARN O95453 Poly(A)-specific ribonuclease PARN chr16 GO:0031330 Not Cancer Driver No 71 0.111 197 22 0.112 2
PDCL3 PDCL3 Q9H2J4 Phosducin-like protein 3 chr2 GO:0031330 Not Cancer Driver No 48 0.201 73 13 0.178 0
PHAX PHAX Q9H814 Phosphorylated adapter RNA export protein chr5 GO:0031330 Not Cancer Driver No 32 0.081 331 29 0.088 0
PHF23 PHF23 Q9BUL5 PHD finger protein 23 chr17 GO:0031330 Not Cancer Driver No 45 0.112 331 37 0.112 0
PIK3CG PIK3CG P48736 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform chr7 GO:0031330 Not Cancer Driver No 318 0.289 121 39 0.322 0
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 GO:0031330 Not Cancer Driver No 57 0.098 99 13 0.131 23
PKP1 PKP1 Q13835 Plakophilin-1 chr1 GO:0031330 Not Cancer Driver No 106 0.142 190 26 0.137 0
PKP3 PKP3 Q9Y446 Plakophilin-3 chr11 GO:0031330 Not Cancer Driver No 72 0.09 357 22 0.062 0
PLIN5 PLIN5 Q00G26 Perilipin-5 chr19 GO:0031330 Not Cancer Driver No 49 0.106 192 21 0.109 0
PML PML P29590 Protein PML chr15 GO:0031330 Census, Compendium Yes 112 0.127 312 34 0.109 0
PSEN1 PSEN1 P49768 Presenilin-1 chr14 GO:0031330 Not Cancer Driver No 61 0.131 134 21 0.157 96
PTPN3 PTPN3 P26045 Tyrosine-protein phosphatase non-receptor type 3 chr9 GO:0031330 Not Cancer Driver No 139 0.152 214 28 0.131 0
QRICH2 QRICH2 Q9H0J4 Glutamine-rich protein 2 chr17 GO:0031330 Not Cancer Driver No 204 0.123 1369 171 0.125 0
RBM10_ENST00000377604 RBM10 P98175 RNA-binding protein 10 chrX GO:0031330 Census, Compendium Yes 112 0.12 777 99 0.127 0
RGN RGN Q15493 Regucalcin chrX GO:0031330 Not Cancer Driver No 38 0.127 14 3 0.214 0
RNF41_ENST00000615206 RNF41 Q9H4P4 E3 ubiquitin-protein ligase NRDP1 chr12 GO:0031330 Not Cancer Driver No 44 0.139 33 2 0.061 0
ROCK1 ROCK1 Q13464 Rho-associated protein kinase 1 chr18 GO:0031330 Not Cancer Driver No 184 0.136 780 103 0.132 0
RPL11 RPL11 P62913 60S ribosomal protein L11 chr1 GO:0031330 Not Cancer Driver No 27 0.152 12 1 0.083 1
RPL23_ENST00000394332 RPL23 P62829 60S ribosomal protein L23 chr17 GO:0031330 Not Cancer Driver No 14 0.1 29 4 0.138 0
RPL5_ENST00000370321 RPL5 P46777 60S ribosomal protein L5 chr1 GO:0031330 Census Yes 57 0.192 96 17 0.177 2
RPS7_ENST00000645674 RPS7 P62081 40S ribosomal protein S7 chr2 GO:0031330 Not Cancer Driver No 29 0.149 39 7 0.179 0
RUBCN RUBCN Q92622 Run domain Beclin-1-interacting and cysteine-rich domain-containing protein chr3 GO:0031330 Not Cancer Driver No 147 0.151 403 57 0.141 0
SCFD1 SCFD1 Q8WVM8 Sec1 family domain-containing protein 1 chr14 GO:0031330 Not Cancer Driver No 66 0.103 117 12 0.103 0
SECISBP2 SECISBP2 Q96T21 Selenocysteine insertion sequence-binding protein 2 chr9 GO:0031330 Not Cancer Driver No 90 0.105 565 50 0.088 1
SGTA SGTA O43765 Small glutamine-rich tetratricopeptide repeat-containing protein alpha chr19 GO:0031330 Not Cancer Driver No 38 0.121 159 23 0.145 0
SLIRP SLIRP Q9GZT3 SRA stem-loop-interacting RNA-binding protein, mitochondrial chr14 GO:0031330 Not Cancer Driver No 7 0.064 41 3 0.073 0
SMCR8 SMCR8 Q8TEV9 Guanine nucleotide exchange protein SMCR8 chr17 GO:0031330 Not Cancer Driver No 107 0.114 357 38 0.106 0
SNCA_ENST00000506244 SNCA P37840 Alpha-synuclein chr4 GO:0031330 Not Cancer Driver No 21 0.15 107 13 0.121 5
SNRNP70 SNRNP70 P08621 U1 small nuclear ribonucleoprotein 70 kDa chr19 GO:0031330 Not Cancer Driver No 38 0.087 416 37 0.089 0
SORL1 SORL1 Q92673 Sortilin-related receptor chr11 GO:0031330 Not Cancer Driver No 374 0.169 87 10 0.115 0
STYX STYX Q8WUJ0 Serine/threonine/tyrosine-interacting protein chr14 GO:0031330 Not Cancer Driver No 20 0.09 30 2 0.067 0
SUFU SUFU Q9UMX1 Suppressor of fused homolog chr10 GO:0031330 Census Yes 55 0.114 199 19 0.095 2
SVIP SVIP Q8NHG7 Small VCP/p97-interacting protein chr11 GO:0031330 Not Cancer Driver No 16 0.208 77 16 0.208 0
SYNCRIP SYNCRIP O60506 Heterogeneous nuclear ribonucleoprotein Q chr6 GO:0031330 Not Cancer Driver No 93 0.149 285 39 0.137 0
TAF1_ENST00000373790 TAF1 P21675 Transcription initiation factor TFIID subunit 1 chrX GO:0031330 Not Cancer Driver No 379 0.202 1152 219 0.19 5
TARDBP TARDBP Q13148 TAR DNA-binding protein 43 chr1 GO:0031330 Not Cancer Driver No 51 0.123 202 15 0.074 27
TENT2_ENST00000428308 TENT2 Q6PIY7 Poly(A) RNA polymerase GLD2 chr5 GO:0031330 Not Cancer Driver No 65 0.134 75 15 0.2 0
TENT4A_ENST00000230859 TENT4A Q5XG87 Terminal nucleotidyltransferase 4A chr5 GO:0031330 Not Cancer Driver No 106 0.137 442 43 0.097 0
TIGAR TIGAR Q9NQ88 Fructose-2,6-bisphosphatase TIGAR chr12 GO:0031330 Not Cancer Driver No 44 0.163 39 9 0.231 0
TIMP1 TIMP1 P01033 Metalloproteinase inhibitor 1 chrX GO:0031330 Not Cancer Driver No 25 0.121 0 0 0.0 0
TIMP2 TIMP2 P16035 Metalloproteinase inhibitor 2 chr17 GO:0031330 Not Cancer Driver No 31 0.141 6 2 0.333 0
TIMP3 TIMP3 P35625 Metalloproteinase inhibitor 3 chr22 GO:0031330 Not Cancer Driver No 43 0.204 3 1 0.333 5
TIMP4 TIMP4 Q99727 Metalloproteinase inhibitor 4 chr3 GO:0031330 Not Cancer Driver No 30 0.134 8 2 0.25 0
TIRAP_ENST00000392680 TIRAP P58753 Toll/interleukin-1 receptor domain-containing adapter protein chr11 GO:0031330 Not Cancer Driver No 28 0.127 80 6 0.075 0
TMEM39A TMEM39A Q9NV64 Transmembrane protein 39A chr3 GO:0031330 Not Cancer Driver No 53 0.109 14 1 0.071 0
TOB1 TOB1 P50616 Protein Tob1 chr17 GO:0031330 Not Cancer Driver No 35 0.101 214 18 0.084 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 GO:0031330 Census, Compendium Yes 2891 7.356 282 1466 5.199 83
TRDMT1 TRDMT1 O14717 tRNA (cytosine(38)-C(5))-methyltransferase chr10 GO:0031330 Not Cancer Driver No 65 0.166 19 3 0.158 0
TRIM39 TRIM39 Q9HCM9 E3 ubiquitin-protein ligase TRIM39 chr6 GO:0031330 Not Cancer Driver No 74 0.143 62 8 0.129 0
TSC2 TSC2 P49815 Tuberin chr16 GO:0031330 Census, Compendium Yes 192 0.106 563 50 0.089 53
TSPO_ENST00000329563 TSPO P30536 Translocator protein chr22 GO:0031330 Not Cancer Driver No 5 0.03 1 0 0.0 0
UBQLN4 UBQLN4 Q9NRR5 Ubiquilin-4 chr1 GO:0031330 Not Cancer Driver No 70 0.116 561 67 0.119 1
UBXN1_ENST00000301935 UBXN1 Q04323 UBX domain-containing protein 1 chr11 GO:0031330 Not Cancer Driver No 35 0.118 271 33 0.122 0
USP14 USP14 P54578 Ubiquitin carboxyl-terminal hydrolase 14 chr18 GO:0031330 Not Cancer Driver No 59 0.119 86 6 0.07 0
USP25_ENST00000285679 USP25 Q9UHP3 Ubiquitin carboxyl-terminal hydrolase 25 chr21 GO:0031330 Not Cancer Driver No 135 0.128 354 55 0.155 0
USP30 USP30 Q70CQ3 Ubiquitin carboxyl-terminal hydrolase 30 chr12 GO:0031330 Not Cancer Driver No 76 0.147 136 26 0.191 0
VPS35 VPS35 Q96QK1 Vacuolar protein sorting-associated protein 35 chr16 GO:0031330 Not Cancer Driver No 68 0.085 99 9 0.091 1
WNT1 WNT1 P04628 Proto-oncogene Wnt-1 chr12 GO:0031330 Not Cancer Driver No 29 0.078 25 0 0.0 8
YBX1 YBX1 P67809 Y-box-binding protein 1 chr1 GO:0031330 Not Cancer Driver No 41 0.127 312 41 0.131 0
YBX3 YBX3 P16989 Y-box-binding protein 3 chr12 GO:0031330 Not Cancer Driver No 49 0.132 359 47 0.131 0
ZCCHC17_ENST00000373714 ZCCHC17 Q9NP64 Zinc finger CCHC domain-containing protein 17 chr1 GO:0031330 Not Cancer Driver No 25 0.104 153 16 0.105 0
ZFP36 ZFP36 P26651 mRNA decay activator protein ZFP36 chr19 GO:0031330 Not Cancer Driver No 43 0.132 262 34 0.13 0