Total number of protein in "GO:0031234" GO term: 64
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKT1_ENST00000349310 | AKT1 | P31749 | RAC-alpha serine/threonine-protein kinase | chr14 | GO:0031234 | Census, Compendium | Yes | 108 | 0.225 | 158 | 24 | 0.152 | 4 |
| ALOX15_ENST00000293761 | ALOX15 | P16050 | Polyunsaturated fatty acid lipoxygenase ALOX15 | chr17 | GO:0031234 | Not Cancer Driver | No | 84 | 0.127 | 46 | 7 | 0.152 | 0 |
| BLK | BLK | P51451 | Tyrosine-protein kinase Blk | chr8 | GO:0031234 | Not Cancer Driver | No | 94 | 0.186 | 75 | 21 | 0.28 | 0 |
| CARMIL2 | CARMIL2 | Q6F5E8 | Capping protein, Arp2/3 and myosin-I linker protein 2 | chr16 | GO:0031234 | Not Cancer Driver | No | 154 | 0.107 | 669 | 75 | 0.112 | 4 |
| CAV2 | CAV2 | P51636 | Caveolin-2 | chr7 | GO:0031234 | Not Cancer Driver | No | 20 | 0.123 | 5 | 2 | 0.4 | 0 |
| CDK16_ENST00000357227 | CDK16 | Q00536 | Cyclin-dependent kinase 16 | chrX | GO:0031234 | Not Cancer Driver | No | 55 | 0.111 | 139 | 30 | 0.216 | 0 |
| CNR2 | CNR2 | P34972 | Cannabinoid receptor 2 | chr1 | GO:0031234 | Not Cancer Driver | No | 57 | 0.158 | 21 | 4 | 0.19 | 0 |
| CYLD | CYLD | Q9NQC7 | Ubiquitin carboxyl-terminal hydrolase CYLD | chr16 | GO:0031234 | Census, Compendium | Yes | 116 | 0.121 | 213 | 31 | 0.146 | 3 |
| CYTH1_ENST00000446868 | CYTH1 | Q15438 | Cytohesin-1 | chr17 | GO:0031234 | Not Cancer Driver | No | 59 | 0.148 | 93 | 15 | 0.161 | 0 |
| CYTH3_ENST00000396741 | CYTH3 | O43739 | Cytohesin-3 | chr7 | GO:0031234 | Not Cancer Driver | No | 49 | 0.122 | 96 | 12 | 0.125 | 0 |
| DLG4_ENST00000399506 | DLG4 | P78352 | Disks large homolog 4 | chr17 | GO:0031234 | Not Cancer Driver | No | 116 | 0.16 | 232 | 55 | 0.237 | 0 |
| ERRFI1 | ERRFI1 | Q9UJM3 | ERBB receptor feedback inhibitor 1 | chr1 | GO:0031234 | Not Cancer Driver | No | 55 | 0.119 | 297 | 37 | 0.125 | 0 |
| ESYT1_ENST00000394048 | ESYT1 | Q9BSJ8 | Extended synaptotagmin-1 | chr12 | GO:0031234 | Not Cancer Driver | No | 126 | 0.114 | 278 | 32 | 0.115 | 0 |
| ESYT2_ENST00000613624 | ESYT2 | A0FGR8 | Extended synaptotagmin-2 | chr7 | GO:0031234 | Not Cancer Driver | No | 94 | 0.102 | 376 | 25 | 0.066 | 0 |
| ESYT3 | ESYT3 | A0FGR9 | Extended synaptotagmin-3 | chr3 | GO:0031234 | Not Cancer Driver | No | 115 | 0.13 | 179 | 18 | 0.101 | 0 |
| FARP1_ENST00000319562 | FARP1 | Q9Y4F1 | FERM, ARHGEF and pleckstrin domain-containing protein 1 | chr13 | GO:0031234 | Not Cancer Driver | No | 147 | 0.141 | 315 | 60 | 0.19 | 0 |
| FER | FER | P16591 | Tyrosine-protein kinase Fer | chr5 | GO:0031234 | Not Cancer Driver | No | 114 | 0.139 | 145 | 21 | 0.145 | 0 |
| FERMT2_ENST00000395631 | FERMT2 | Q96AC1 | Fermitin family homolog 2 | chr14 | GO:0031234 | Not Cancer Driver | No | 71 | 0.104 | 101 | 10 | 0.099 | 0 |
| FES | FES | P07332 | Tyrosine-protein kinase Fes/Fps | chr15 | GO:0031234 | Census | Yes | 103 | 0.125 | 245 | 34 | 0.139 | 0 |
| FGR_ENST00000374004 | FGR | P09769 | Tyrosine-protein kinase Fgr | chr1 | GO:0031234 | Not Cancer Driver | No | 85 | 0.161 | 52 | 8 | 0.154 | 0 |
| FRK | FRK | P42685 | Tyrosine-protein kinase FRK | chr6 | GO:0031234 | Not Cancer Driver | No | 87 | 0.172 | 18 | 2 | 0.111 | 0 |
| FYN | FYN | P06241 | Tyrosine-protein kinase Fyn | chr6 | GO:0031234 | Not Cancer Driver | No | 92 | 0.171 | 70 | 13 | 0.186 | 0 |
| GRAMD1A | GRAMD1A | Q96CP6 | Protein Aster-A | chr19 | GO:0031234 | Not Cancer Driver | No | 83 | 0.115 | 261 | 33 | 0.126 | 0 |
| GRAMD2A | GRAMD2A | Q8IUY3 | GRAM domain-containing protein 2A | chr15 | GO:0031234 | Not Cancer Driver | No | 49 | 0.138 | 106 | 8 | 0.075 | 0 |
| HCK_ENST00000534862 | HCK | P08631 | Tyrosine-protein kinase HCK | chr20 | GO:0031234 | Not Cancer Driver | No | 112 | 0.213 | 124 | 25 | 0.202 | 0 |
| HIP1 | HIP1 | O00291 | Huntingtin-interacting protein 1 | chr7 | GO:0031234 | Census, Compendium | Yes | 137 | 0.132 | 510 | 70 | 0.137 | 0 |
| IQGAP1 | IQGAP1 | P46940 | Ras GTPase-activating-like protein IQGAP1 | chr15 | GO:0031234 | Not Cancer Driver | No | 183 | 0.11 | 351 | 35 | 0.1 | 0 |
| KCNAB1 | KCNAB1 | Q14722 | Voltage-gated potassium channel subunit beta-1 | chr3 | GO:0031234 | Not Cancer Driver | No | 89 | 0.212 | 83 | 23 | 0.277 | 0 |
| KCNAB2_ENST00000378097 | KCNAB2 | Q13303 | Voltage-gated potassium channel subunit beta-2 | chr1 | GO:0031234 | Not Cancer Driver | No | 41 | 0.112 | 33 | 1 | 0.03 | 0 |
| KCNIP1_ENST00000411494 | KCNIP1 | Q9NZI2 | Kv channel-interacting protein 1 | chr5 | GO:0031234 | Not Cancer Driver | No | 58 | 0.256 | 4 | 1 | 0.25 | 0 |
| KRAS | KRAS | P01116 | GTPase KRas | chr12 | GO:0031234 | Census, Compendium | Yes | 788 | 4.169 | 7 | 2 | 0.286 | 27 |
| LCK | LCK | P06239 | Tyrosine-protein kinase Lck | chr1 | GO:0031234 | Census | Yes | 86 | 0.169 | 94 | 13 | 0.138 | 1 |
| LYN | LYN | P07948 | Tyrosine-protein kinase Lyn | chr8 | GO:0031234 | Census | Yes | 95 | 0.186 | 84 | 12 | 0.143 | 0 |
| MYZAP | MYZAP | P0CAP1 | Myocardial zonula adherens protein | chr15 | GO:0031234 | Not Cancer Driver | No | 92 | 0.197 | 358 | 76 | 0.212 | 0 |
| OSBPL2_ENST00000643981 | OSBPL2 | Q9H1P3 | Oxysterol-binding protein-related protein 2 | chr20 | GO:0031234 | Not Cancer Driver | No | 57 | 0.119 | 173 | 18 | 0.104 | 0 |
| PLEKHA4 | PLEKHA4 | Q9H4M7 | Pleckstrin homology domain-containing family A member 4 | chr19 | GO:0031234 | Not Cancer Driver | No | 136 | 0.175 | 687 | 128 | 0.186 | 0 |
| PTK2B_ENST00000346049 | PTK2B | Q14289 | Protein-tyrosine kinase 2-beta | chr8 | GO:0031234 | Not Cancer Driver | No | 161 | 0.16 | 261 | 37 | 0.142 | 0 |
| PTK2_ENST00000522684 | PTK2 | Q05397 | Focal adhesion kinase 1 | chr8 | GO:0031234 | Not Cancer Driver | No | 134 | 0.127 | 425 | 55 | 0.129 | 0 |
| PTK6 | PTK6 | Q13882 | Protein-tyrosine kinase 6 | chr20 | GO:0031234 | Census | Yes | 42 | 0.093 | 12 | 0 | 0.0 | 0 |
| RAC1_ENST00000348035 | RAC1 | P63000 | Ras-related C3 botulinum toxin substrate 1 | chr7 | GO:0031234 | Census, Compendium | Yes | 66 | 0.344 | 2 | 1 | 0.5 | 6 |
| RACGAP1_ENST00000454520 | RACGAP1 | Q9H0H5 | Rac GTPase-activating protein 1 | chr12 | GO:0031234 | Not Cancer Driver | No | 74 | 0.117 | 255 | 27 | 0.106 | 0 |
| RGS1 | RGS1 | Q08116 | Regulator of G-protein signaling 1 | chr1 | GO:0031234 | Not Cancer Driver | No | 50 | 0.239 | 45 | 12 | 0.267 | 0 |
| RGS8_ENST00000367556 | RGS8 | P57771 | Regulator of G-protein signaling 8 | chr1 | GO:0031234 | Not Cancer Driver | No | 41 | 0.228 | 20 | 5 | 0.25 | 0 |
| RHOA | RHOA | P61586 | Transforming protein RhoA | chr3 | GO:0031234 | Census, Compendium | Yes | 99 | 0.513 | 46 | 13 | 0.283 | 2 |
| S100A6_ENST00000496817 | S100A6 | P06703 | Protein S100-A6 | chr1 | GO:0031234 | Not Cancer Driver | No | 5 | 0.056 | 4 | 0 | 0.0 | 0 |
| SLA_ENST00000338087 | SLA | Q13239 | Src-like-adapter | chr8 | GO:0031234 | Not Cancer Driver | No | 59 | 0.214 | 51 | 11 | 0.216 | 0 |
| SNAP25 | SNAP25 | P60880 | Synaptosomal-associated protein 25 | chr20 | GO:0031234 | Not Cancer Driver | No | 61 | 0.296 | 176 | 49 | 0.278 | 1 |
| SNX18 | SNX18 | Q96RF0 | Sorting nexin-18 | chr5 | GO:0031234 | Not Cancer Driver | No | 54 | 0.086 | 236 | 7 | 0.03 | 0 |
| SNX5_ENST00000377759 | SNX5 | Q9Y5X3 | Sorting nexin-5 | chr20 | GO:0031234 | Not Cancer Driver | No | 33 | 0.082 | 91 | 13 | 0.143 | 0 |
| SNX9 | SNX9 | Q9Y5X1 | Sorting nexin-9 | chr6 | GO:0031234 | Not Cancer Driver | No | 71 | 0.119 | 231 | 23 | 0.1 | 0 |
| SRC_ENST00000358208 | SRC | P12931 | Proto-oncogene tyrosine-protein kinase Src | chr20 | GO:0031234 | Census | Yes | 53 | 0.099 | 130 | 11 | 0.085 | 1 |
| SRMS | SRMS | Q9H3Y6 | Tyrosine-protein kinase Srms | chr20 | GO:0031234 | Not Cancer Driver | No | 77 | 0.158 | 48 | 11 | 0.229 | 0 |
| STAC | STAC | Q99469 | SH3 and cysteine-rich domain-containing protein | chr3 | GO:0031234 | Not Cancer Driver | No | 107 | 0.266 | 196 | 55 | 0.281 | 0 |
| STAC2 | STAC2 | Q6ZMT1 | SH3 and cysteine-rich domain-containing protein 2 | chr17 | GO:0031234 | Not Cancer Driver | No | 56 | 0.136 | 228 | 36 | 0.158 | 0 |
| STAC3 | STAC3 | Q96MF2 | SH3 and cysteine-rich domain-containing protein 3 | chr12 | GO:0031234 | Not Cancer Driver | No | 50 | 0.137 | 192 | 30 | 0.156 | 1 |
| STYK1 | STYK1 | Q6J9G0 | Tyrosine-protein kinase STYK1 | chr12 | GO:0031234 | Not Cancer Driver | No | 83 | 0.197 | 35 | 10 | 0.286 | 0 |
| SYAP1 | SYAP1 | Q96A49 | Synapse-associated protein 1 | chrX | GO:0031234 | Not Cancer Driver | No | 31 | 0.088 | 221 | 22 | 0.1 | 0 |
| SYK_ENST00000375746 | SYK | P43405 | Tyrosine-protein kinase SYK | chr9 | GO:0031234 | Census | Yes | 96 | 0.151 | 131 | 27 | 0.206 | 5 |
| TGM3 | TGM3 | Q08188 | Protein-glutamine gamma-glutamyltransferase E | chr20 | GO:0031234 | Not Cancer Driver | No | 141 | 0.203 | 85 | 19 | 0.224 | 0 |
| TIAM1 | TIAM1 | Q13009 | Rho guanine nucleotide exchange factor TIAM1 | chr21 | GO:0031234 | Not Cancer Driver | No | 370 | 0.233 | 810 | 194 | 0.24 | 0 |
| TNK1 | TNK1 | Q13470 | Non-receptor tyrosine-protein kinase TNK1 | chr17 | GO:0031234 | Not Cancer Driver | No | 51 | 0.077 | 298 | 24 | 0.081 | 0 |
| TNK2_ENST00000333602 | TNK2 | Q07912 | Activated CDC42 kinase 1 | chr3 | GO:0031234 | Not Cancer Driver | No | 137 | 0.132 | 593 | 81 | 0.137 | 0 |
| YES1_ENST00000314574 | YES1 | P07947 | Tyrosine-protein kinase Yes | chr18 | GO:0031234 | Not Cancer Driver | No | 65 | 0.12 | 62 | 10 | 0.161 | 0 |
| ZAP70 | ZAP70 | P43403 | Tyrosine-protein kinase ZAP-70 | chr2 | GO:0031234 | Not Cancer Driver | No | 126 | 0.204 | 117 | 17 | 0.145 | 8 |