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Total number of protein in "GO:0031224" GO term:  243

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABHD17A_ENST00000292577 ABHD17A Q96GS6 Alpha/beta hydrolase domain-containing protein 17A chr19 GO:0031224 Not Cancer Driver No 35 0.113 20 5 0.25 0
ADAM23 ADAM23 O75077 Disintegrin and metalloproteinase domain-containing protein 23 chr2 GO:0031224 Not Cancer Driver No 175 0.21 162 26 0.16 0
ADAM9 ADAM9 Q13443 Disintegrin and metalloproteinase domain-containing protein 9 chr8 GO:0031224 Not Cancer Driver No 86 0.105 129 13 0.101 0
ADCY8 ADCY8 P40145 Adenylate cyclase type 8 chr8 GO:0031224 Not Cancer Driver No 419 0.335 215 38 0.177 0
ADORA1 ADORA1 P30542 Adenosine receptor A1 chr1 GO:0031224 Not Cancer Driver No 64 0.196 12 4 0.333 0
ADORA2A ADORA2A P29274 Adenosine receptor A2a chr22 GO:0031224 Not Cancer Driver No 61 0.148 93 11 0.118 0
ADRA1A_ENST00000380573 ADRA1A P35348 Alpha-1A adrenergic receptor chr8 GO:0031224 Not Cancer Driver No 130 0.279 40 8 0.2 0
ADRA2A ADRA2A P08913 Alpha-2A adrenergic receptor chr10 GO:0031224 Not Cancer Driver No 67 0.144 161 10 0.062 0
AJAP1 AJAP1 Q9UKB5 Adherens junction-associated protein 1 chr1 GO:0031224 Not Cancer Driver No 103 0.251 271 64 0.236 0
APH1A APH1A Q96BI3 Gamma-secretase subunit APH-1A chr1 GO:0031224 Not Cancer Driver No 32 0.121 0 0 0.0 0
APOL1_ENST00000397279 APOL1 O14791 Apolipoprotein L1 chr22 GO:0031224 Not Cancer Driver No 51 0.128 82 9 0.11 2
ATP10B ATP10B O94823 Phospholipid-transporting ATPase VB chr5 GO:0031224 Not Cancer Driver No 310 0.212 333 66 0.198 0
ATP13A2 ATP13A2 Q9NQ11 Polyamine-transporting ATPase 13A2 chr1 GO:0031224 Not Cancer Driver No 152 0.129 121 10 0.083 9
ATP2B1_ENST00000261173 ATP2B1 P20020 Plasma membrane calcium-transporting ATPase 1 chr12 GO:0031224 Not Cancer Driver No 143 0.117 293 42 0.143 0
ATP2B2 ATP2B2 Q01814 Plasma membrane calcium-transporting ATPase 2 chr3 GO:0031224 Not Cancer Driver No 248 0.2 360 82 0.228 0
ATP2B3_ENST00000349466 ATP2B3 Q16720 Plasma membrane calcium-transporting ATPase 3 chrX GO:0031224 Census Yes 245 0.201 328 74 0.226 2
BCAP31_ENST00000345046 BCAP31 P51572 B-cell receptor-associated protein 31 chrX GO:0031224 Not Cancer Driver No 37 0.15 104 14 0.135 0
BMPR2 BMPR2 Q13873 Bone morphogenetic protein receptor type-2 chr2 GO:0031224 Compendium Yes 141 0.136 601 70 0.116 19
BNIP3L BNIP3L O60238 BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like chr8 GO:0031224 Not Cancer Driver No 16 0.073 175 14 0.08 0
BORCS5 BORCS5 Q969J3 BLOC-1-related complex subunit 5 chr12 GO:0031224 Not Cancer Driver No 24 0.122 89 14 0.157 0
CA4 CA4 P22748 Carbonic anhydrase 4 chr17 GO:0031224 Not Cancer Driver No 55 0.176 81 12 0.148 4
CADM3_ENST00000368125 CADM3 Q8N126 Cell adhesion molecule 3 chr1 GO:0031224 Not Cancer Driver No 120 0.302 170 65 0.382 0
CALR CALR P27797 Calreticulin chr19 GO:0031224 Census Yes 45 0.108 245 31 0.127 0
CANX_ENST00000504734 CANX P27824 Calnexin chr5 GO:0031224 Not Cancer Driver No 65 0.11 334 38 0.114 0
CD14 CD14 P08571 Monocyte differentiation antigen CD14 chr5 GO:0031224 Not Cancer Driver No 42 0.112 60 5 0.083 0
CD59_ENST00000395850 CD59 P13987 CD59 glycoprotein chr11 GO:0031224 Not Cancer Driver No 18 0.141 0 0 0.0 1
CD6 CD6 P30203 T-cell differentiation antigen CD6 chr11 GO:0031224 Not Cancer Driver No 91 0.136 268 41 0.153 0
CD74 CD74 P04233 HLA class II histocompatibility antigen gamma chain chr5 GO:0031224 Census Yes 31 0.105 185 20 0.108 0
CDH10 CDH10 Q9Y6N8 Cadherin-10 chr5 GO:0031224 Census, Compendium Yes 496 0.629 287 179 0.624 0
CDH2 CDH2 P19022 Cadherin-2 chr18 GO:0031224 Not Cancer Driver No 238 0.263 461 130 0.282 7
CDHR2 CDHR2 Q9BYE9 Cadherin-related family member 2 chr5 GO:0031224 Not Cancer Driver No 237 0.181 251 52 0.207 0
CDHR5 CDHR5 Q9HBB8 Cadherin-related family member 5 chr11 GO:0031224 Not Cancer Driver No 112 0.133 503 70 0.139 0
CEACAM5 CEACAM5 P06731 Carcinoembryonic antigen-related cell adhesion molecule 5 chr19 GO:0031224 Not Cancer Driver No 135 0.192 256 48 0.188 0
CHRM1 CHRM1 P11229 Muscarinic acetylcholine receptor M1 chr11 GO:0031224 Not Cancer Driver No 63 0.137 131 24 0.183 0
CHRNA6 CHRNA6 Q15825 Neuronal acetylcholine receptor subunit alpha-6 chr8 GO:0031224 Not Cancer Driver No 101 0.204 33 6 0.182 0
CHRNB2 CHRNB2 P17787 Neuronal acetylcholine receptor subunit beta-2 chr1 GO:0031224 Not Cancer Driver No 92 0.183 23 2 0.087 2
CHST2 CHST2 Q9Y4C5 Carbohydrate sulfotransferase 2 chr3 GO:0031224 Not Cancer Driver No 98 0.185 136 11 0.081 0
CHST4_ENST00000539698 CHST4 Q8NCG5 Carbohydrate sulfotransferase 4 chr16 GO:0031224 Not Cancer Driver No 59 0.153 7 0 0.0 0
CHST5 CHST5 Q9GZS9 Carbohydrate sulfotransferase 5 chr16 GO:0031224 Not Cancer Driver No 98 0.238 23 4 0.174 0
CNR1_ENST00000549890 CNR1 P21554 Cannabinoid receptor 1 chr6 GO:0031224 Not Cancer Driver No 129 0.273 9 1 0.111 0
CNTN1 CNTN1 Q12860 Contactin-1 chr12 GO:0031224 Not Cancer Driver No 265 0.26 220 50 0.227 0
CNTN2 CNTN2 Q02246 Contactin-2 chr1 GO:0031224 Not Cancer Driver No 155 0.149 370 61 0.165 0
CNTN5_ENST00000528682 CNTN5 O94779 Contactin-5 chr11 GO:0031224 Not Cancer Driver No 380 0.345 290 74 0.255 0
CNTN6_ENST00000350110 CNTN6 Q9UQ52 Contactin-6 chr3 GO:0031224 Not Cancer Driver No 330 0.321 173 59 0.341 0
CPLX3 CPLX3 Q8WVH0 Complexin-3 chr15 GO:0031224 Not Cancer Driver No 26 0.165 149 25 0.168 0
DLG4_ENST00000399506 DLG4 P78352 Disks large homolog 4 chr17 GO:0031224 Not Cancer Driver No 116 0.16 232 55 0.237 0
DNAJC5 DNAJC5 Q9H3Z4 DnaJ homolog subfamily C member 5 chr20 GO:0031224 Not Cancer Driver No 23 0.116 46 6 0.13 1
DRD1 DRD1 P21728 D(1A) dopamine receptor chr5 GO:0031224 Not Cancer Driver No 73 0.164 30 4 0.133 0
DRD2_ENST00000542968 DRD2 P14416 D(2) dopamine receptor chr11 GO:0031224 Not Cancer Driver No 127 0.287 124 45 0.363 0
ECE1 ECE1 P42892 Endothelin-converting enzyme 1 chr1 GO:0031224 Not Cancer Driver No 118 0.153 99 26 0.263 1
EFNA5 EFNA5 P52803 Ephrin-A5 chr5 GO:0031224 Not Cancer Driver No 34 0.149 25 6 0.24 0
EFNB2_ENST00000245323 EFNB2 P52799 Ephrin-B2 chr13 GO:0031224 Not Cancer Driver No 42 0.126 97 15 0.155 0
EFNB3 EFNB3 Q15768 Ephrin-B3 chr17 GO:0031224 Not Cancer Driver No 45 0.132 183 22 0.12 0
EMC6 EMC6 Q9BV81 ER membrane protein complex subunit 6 chr17 GO:0031224 Not Cancer Driver No 4 0.036 0 0 0.0 0
ENTPD4 ENTPD4 Q9Y227 Ectonucleoside triphosphate diphosphohydrolase 4 chr8 GO:0031224 Not Cancer Driver No 67 0.109 26 2 0.077 0
EPHA4_ENST00000409938 EPHA4 P54764 Ephrin type-A receptor 4 chr2 GO:0031224 Not Cancer Driver No 182 0.185 140 24 0.171 0
EPHB2 EPHB2 P29323 Ephrin type-B receptor 2 chr1 GO:0031224 Not Cancer Driver No 186 0.176 119 17 0.143 7
ERBB4 ERBB4 Q15303 Receptor tyrosine-protein kinase erbB-4 chr2 GO:0031224 Census, Compendium Yes 428 0.327 323 116 0.359 2
F10 F10 P00742 Coagulation factor X chr13 GO:0031224 Not Cancer Driver No 98 0.201 120 24 0.2 26
F3 F3 P13726 Tissue factor chr1 GO:0031224 Not Cancer Driver No 28 0.095 61 7 0.115 0
FAM210B FAM210B Q96KR6 Protein FAM210B, mitochondrial chr20 GO:0031224 Not Cancer Driver No 10 0.052 32 0 0.0 0
FOLR1_ENST00000393681 FOLR1 P15328 Folate receptor alpha chr11 GO:0031224 Not Cancer Driver No 41 0.16 13 3 0.231 0
FOLR2 FOLR2 P14207 Folate receptor beta chr11 GO:0031224 Not Cancer Driver No 32 0.125 6 0 0.0 0
FOLR3 FOLR3 P41439 Folate receptor gamma chr11 GO:0031224 Not Cancer Driver No 58 0.237 15 4 0.267 0
FXYD6_ENST00000260282 FXYD6 Q9H0Q3 FXYD domain-containing ion transport regulator 6 chr11 GO:0031224 Not Cancer Driver No 14 0.147 27 4 0.148 0
GABBR1 GABBR1 Q9UBS5 Gamma-aminobutyric acid type B receptor subunit 1 chr6 GO:0031224 Not Cancer Driver No 150 0.156 142 17 0.12 0
GABRA2_ENST00000356504 GABRA2 P47869 Gamma-aminobutyric acid receptor subunit alpha-2 chr4 GO:0031224 Not Cancer Driver No 194 0.43 26 13 0.5 5
GABRA5_ENST00000355395 GABRA5 P31644 Gamma-aminobutyric acid receptor subunit alpha-5 chr15 GO:0031224 Not Cancer Driver No 146 0.316 55 14 0.255 3
GOLGA7_ENST00000518270 GOLGA7 Q7Z5G4 Golgin subfamily A member 7 chr8 GO:0031224 Not Cancer Driver No 8 0.058 6 0 0.0 0
GP1BA GP1BA P07359 Platelet glycoprotein Ib alpha chain chr17 GO:0031224 Not Cancer Driver No 65 0.1 247 18 0.073 9
GP2 GP2 P55259 Pancreatic secretory granule membrane major glycoprotein GP2 chr16 GO:0031224 Not Cancer Driver No 144 0.268 25 4 0.16 0
GPHN_ENST00000315266 GPHN Q9NQX3 Gephyrin chr14 GO:0031224 Census Yes 126 0.171 305 41 0.134 2
GPIHBP1 GPIHBP1 Q8IV16 Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 chr8 GO:0031224 Not Cancer Driver No 26 0.141 82 15 0.183 10
GPM6A_ENST00000393658 GPM6A P51674 Neuronal membrane glycoprotein M6-a chr4 GO:0031224 Not Cancer Driver No 83 0.299 15 5 0.333 0
GRIK4_ENST00000438375 GRIK4 Q16099 Glutamate receptor ionotropic, kainate 4 chr11 GO:0031224 Not Cancer Driver No 179 0.187 74 8 0.108 0
GRIK5_ENST00000593562 GRIK5 Q16478 Glutamate receptor ionotropic, kainate 5 chr19 GO:0031224 Not Cancer Driver No 176 0.18 135 9 0.067 0
GRM3 GRM3 Q14832 Metabotropic glutamate receptor 3 chr7 GO:0031224 Census Yes 323 0.367 8 3 0.375 0
HLA-A_ENST00000376809 HLA-A P04439 HLA class I histocompatibility antigen, A alpha chain chr6 GO:0031224 Census, Compendium Yes 128 0.351 125 60 0.48 0
HLA-B HLA-B P01889 HLA class I histocompatibility antigen, B alpha chain chr6 GO:0031224 Compendium Yes 78 0.215 169 34 0.201 0
HLA-C HLA-C P10321 HLA class I histocompatibility antigen, C alpha chain chr6 GO:0031224 Not Cancer Driver No 104 0.284 175 58 0.331 0
HLA-DPA1 HLA-DPA1 P20036 HLA class II histocompatibility antigen, DP alpha 1 chain chr6 GO:0031224 Not Cancer Driver No 37 0.142 30 4 0.133 0
HLA-DPB1 HLA-DPB1 P04440 HLA class II histocompatibility antigen, DP beta 1 chain chr6 GO:0031224 Not Cancer Driver No 38 0.147 39 4 0.103 0
HLA-DQA2 HLA-DQA2 P01906 HLA class II histocompatibility antigen, DQ alpha 2 chain chr6 GO:0031224 Not Cancer Driver No 61 0.239 7 0 0.0 0
HLA-DQB2 HLA-DQB2 P05538 HLA class II histocompatibility antigen, DQ beta 2 chain chr6 GO:0031224 Not Cancer Driver No 55 0.205 38 5 0.132 0
HLA-DRA HLA-DRA P01903 HLA class II histocompatibility antigen, DR alpha chain chr6 GO:0031224 Not Cancer Driver No 52 0.205 12 1 0.083 0
HLA-DRB1 HLA-DRB1 P01911 HLA class II histocompatibility antigen, DRB1 beta chain chr6 GO:0031224 Not Cancer Driver No 48 0.18 12 1 0.083 0
HLA-DRB5 HLA-DRB5 Q30154 HLA class II histocompatibility antigen, DR beta 5 chain chr6 GO:0031224 Not Cancer Driver No 35 0.132 18 2 0.111 0
HLA-E HLA-E P13747 HLA class I histocompatibility antigen, alpha chain E chr6 GO:0031224 Not Cancer Driver No 63 0.176 138 39 0.283 0
HLA-F_ENST00000376861 HLA-F P30511 HLA class I histocompatibility antigen, alpha chain F chr6 GO:0031224 Not Cancer Driver No 43 0.124 115 22 0.191 0
HLA-G_ENST00000360323 HLA-G P17693 HLA class I histocompatibility antigen, alpha chain G chr6 GO:0031224 Not Cancer Driver No 94 0.278 85 22 0.259 0
HM13_ENST00000340852 HM13 Q8TCT9 Minor histocompatibility antigen H13 chr20 GO:0031224 Not Cancer Driver No 42 0.111 61 6 0.098 0
HTR1B HTR1B P28222 5-hydroxytryptamine receptor 1B chr6 GO:0031224 Not Cancer Driver No 91 0.233 33 15 0.455 0
HTR2A HTR2A P28223 5-hydroxytryptamine receptor 2A chr13 GO:0031224 Not Cancer Driver No 105 0.223 44 8 0.182 0
HYAL2_ENST00000357750 HYAL2 Q12891 Hyaluronidase-2 chr3 GO:0031224 Not Cancer Driver No 52 0.11 8 1 0.125 0
IGSF21 IGSF21 Q96ID5 Immunoglobulin superfamily member 21 chr1 GO:0031224 Not Cancer Driver No 119 0.255 183 47 0.257 0
IZUMO1R IZUMO1R A6ND01 Sperm-egg fusion protein Juno chr11 GO:0031224 Not Cancer Driver No 41 0.164 0 0 0.0 0
KCNA1 KCNA1 Q09470 Potassium voltage-gated channel subfamily A member 1 chr12 GO:0031224 Not Cancer Driver No 176 0.356 69 34 0.493 17
KCNA2_ENST00000638616 KCNA2 P16389 Potassium voltage-gated channel subfamily A member 2 chr1 GO:0031224 Not Cancer Driver No 96 0.192 82 16 0.195 5
KCNA3 KCNA3 P22001 Potassium voltage-gated channel subfamily A member 3 chr1 GO:0031224 Not Cancer Driver No 120 0.209 169 16 0.095 0
KCNC1_ENST00000379472 KCNC1 P48547 Potassium voltage-gated channel subfamily C member 1 chr11 GO:0031224 Not Cancer Driver No 91 0.178 110 18 0.164 1
KCNJ12_ENST00000331718 KCNJ12 Q14500 ATP-sensitive inward rectifier potassium channel 12 chr17 GO:0031224 Not Cancer Driver No 248 0.573 50 27 0.54 0
KCNJ2_ENST00000535240 KCNJ2 P63252 Inward rectifier potassium channel 2 chr17 GO:0031224 Not Cancer Driver No 103 0.241 49 11 0.224 12
KCNJ3 KCNJ3 P48549 G protein-activated inward rectifier potassium channel 1 chr2 GO:0031224 Not Cancer Driver No 189 0.377 162 64 0.395 0
KCNJ9 KCNJ9 Q92806 G protein-activated inward rectifier potassium channel 3 chr1 GO:0031224 Not Cancer Driver No 47 0.12 67 1 0.015 0
LAMP2_ENST00000200639 LAMP2 P13473 Lysosome-associated membrane glycoprotein 2 chrX GO:0031224 Not Cancer Driver No 43 0.105 55 7 0.127 1
LBR_ENST00000272163 LBR Q14739 Delta(14)-sterol reductase LBR chr1 GO:0031224 Not Cancer Driver No 95 0.154 130 15 0.115 5
LEMD2_ENST00000614475 LEMD2 Q8NC56 LEM domain-containing protein 2 chr6 GO:0031224 Not Cancer Driver No 44 0.087 211 4 0.019 2
LEMD3 LEMD3 Q9Y2U8 Inner nuclear membrane protein Man1 chr12 GO:0031224 Not Cancer Driver No 78 0.086 509 33 0.065 0
LILRB4 LILRB4 Q8NHJ6 Leukocyte immunoglobulin-like receptor subfamily B member 4 chr19 GO:0031224 Not Cancer Driver No 162 0.362 277 115 0.415 0
LRFN3 LRFN3 Q9BTN0 Leucine-rich repeat and fibronectin type-III domain-containing protein 3 chr19 GO:0031224 Not Cancer Driver No 77 0.123 212 20 0.094 0
LRRC8A_ENST00000372599 LRRC8A Q8IWT6 Volume-regulated anion channel subunit LRRC8A chr9 GO:0031224 Not Cancer Driver No 105 0.13 32 3 0.094 0
LRRC8E LRRC8E Q6NSJ5 Volume-regulated anion channel subunit LRRC8E chr19 GO:0031224 Not Cancer Driver No 77 0.097 35 0 0.0 0
MAJIN_ENST00000530444 MAJIN Q3KP22 Membrane-anchored junction protein chr11 GO:0031224 Not Cancer Driver No 17 0.097 143 15 0.105 0
MAL2 MAL2 Q969L2 Protein MAL2 chr8 GO:0031224 Not Cancer Driver No 20 0.114 4 0 0.0 0
MCUB MCUB Q9NWR8 Calcium uniporter regulatory subunit MCUb, mitochondrial chr4 GO:0031224 Not Cancer Driver No 33 0.098 24 1 0.042 0
MFN1 MFN1 Q8IWA4 Mitofusin-1 chr3 GO:0031224 Not Cancer Driver No 90 0.121 64 5 0.078 0
MFN2_ENST00000444836 MFN2 O95140 Mitofusin-2 chr1 GO:0031224 Not Cancer Driver No 80 0.106 81 9 0.111 20
MIEN1_ENST00000394231 MIEN1 Q9BRT3 Migration and invasion enhancer 1 chr17 GO:0031224 Not Cancer Driver No 17 0.148 37 4 0.108 0
MTSS1L MTSS2 Q765P7 Protein MTSS 2 chr16 GO:0031224 Not Cancer Driver No 62 0.083 582 49 0.084 0
MTSS1_ENST00000518547 MTSS1 O43312 Protein MTSS 1 chr8 GO:0031224 Not Cancer Driver No 107 0.142 584 86 0.147 0
NCSTN NCSTN Q92542 Nicastrin chr1 GO:0031224 Not Cancer Driver No 94 0.133 72 11 0.153 1
NECTIN1 NECTIN1 Q15223 Nectin-1 chr11 GO:0031224 Not Cancer Driver No 84 0.162 217 36 0.166 0
NLGN1_ENST00000361589 NLGN1 Q8N2Q7 Neuroligin-1 chr3 GO:0031224 Not Cancer Driver No 214 0.248 248 61 0.246 4
NLGN2 NLGN2 Q8NFZ4 Neuroligin-2 chr17 GO:0031224 Not Cancer Driver No 91 0.109 300 19 0.063 0
NLGN3 NLGN3 Q9NZ94 Neuroligin-3 chrX GO:0031224 Not Cancer Driver No 158 0.186 257 54 0.21 2
NLGN4X_ENST00000381093 NLGN4X Q8N0W4 Neuroligin-4, X-linked chrX GO:0031224 Not Cancer Driver No 279 0.342 211 81 0.384 0
NLGN4Y NLGN4Y Q8NFZ3 Neuroligin-4, Y-linked chrY GO:0031224 Not Cancer Driver No 94 0.115 206 26 0.126 0
NPC1 NPC1 O15118 NPC intracellular cholesterol transporter 1 chr18 GO:0031224 Not Cancer Driver No 155 0.121 24 0 0.0 150
NPC1L1 NPC1L1 Q9UHC9 NPC1-like intracellular cholesterol transporter 1 chr7 GO:0031224 Not Cancer Driver No 222 0.163 8 2 0.25 0
NPHS2 NPHS2 Q9NP85 Podocin chr1 GO:0031224 Not Cancer Driver No 72 0.188 130 18 0.138 50
NPTN NPTN Q9Y639 Neuroplastin chr15 GO:0031224 Not Cancer Driver No 47 0.118 118 9 0.076 0
NTNG1_ENST00000370073 NTNG1 Q9Y2I2 Netrin-G1 chr1 GO:0031224 Not Cancer Driver No 149 0.276 1 0 0.0 0
NTNG2 NTNG2 Q96CW9 Netrin-G2 chr9 GO:0031224 Not Cancer Driver No 91 0.172 8 4 0.5 7
OPRD1 OPRD1 P41143 Delta-type opioid receptor chr1 GO:0031224 Not Cancer Driver No 91 0.245 30 3 0.1 0
OPRK1_ENST00000520287 OPRK1 P41145 Kappa-type opioid receptor chr8 GO:0031224 Not Cancer Driver No 117 0.308 18 5 0.278 0
OPRM1_ENST00000330432 OPRM1 P35372 Mu-type opioid receptor chr6 GO:0031224 Not Cancer Driver No 107 0.268 58 27 0.466 0
P2RX1 P2RX1 P51575 P2X purinoceptor 1 chr17 GO:0031224 Not Cancer Driver No 59 0.148 14 1 0.071 0
P2RX2_ENST00000643471 P2RX2 Q9UBL9 P2X purinoceptor 2 chr12 GO:0031224 Not Cancer Driver No 62 0.132 104 13 0.125 2
P2RX3 P2RX3 P56373 P2X purinoceptor 3 chr11 GO:0031224 Not Cancer Driver No 85 0.214 15 6 0.4 0
P2RX4_ENST00000337233 P2RX4 Q99571 P2X purinoceptor 4 chr12 GO:0031224 Not Cancer Driver No 36 0.093 0 0 0.0 0
P2RX5 P2RX5 Q93086 P2X purinoceptor 5 chr17 GO:0031224 Not Cancer Driver No 58 0.137 73 14 0.192 0
P2RX6 P2RX6 O15547 P2X purinoceptor 6 chr22 GO:0031224 Not Cancer Driver No 33 0.075 43 1 0.023 0
P2RX7 P2RX7 Q99572 P2X purinoceptor 7 chr12 GO:0031224 Not Cancer Driver No 51 0.086 14 2 0.143 0
P2RY1 P2RY1 P47900 P2Y purinoceptor 1 chr3 GO:0031224 Not Cancer Driver No 60 0.161 16 1 0.062 0
P2RY12 P2RY12 Q9H244 P2Y purinoceptor 12 chr3 GO:0031224 Not Cancer Driver No 57 0.167 21 2 0.095 3
P2RY4 P2RY4 P51582 P2Y purinoceptor 4 chrX GO:0031224 Not Cancer Driver No 66 0.181 10 2 0.2 0
PALM PALM O75781 Paralemmin-1 chr19 GO:0031224 Not Cancer Driver No 50 0.129 381 50 0.131 0
PCDH17 PCDH17 O14917 Protocadherin-17 chr13 GO:0031224 Compendium Yes 399 0.344 643 210 0.327 0
PEX11G PEX11G Q96HA9 Peroxisomal membrane protein 11C chr19 GO:0031224 Not Cancer Driver No 18 0.075 20 1 0.05 0
PI4K2A PI4K2A Q9BTU6 Phosphatidylinositol 4-kinase type 2-alpha chr10 GO:0031224 Not Cancer Driver No 43 0.09 129 6 0.047 0
PICALM PICALM Q13492 Phosphatidylinositol-binding clathrin assembly protein chr11 GO:0031224 Census Yes 89 0.137 320 42 0.131 0
PKD2 PKD2 Q13563 Polycystin-2 chr4 GO:0031224 Not Cancer Driver No 113 0.117 375 35 0.093 10
PKHD1 PKHD1 P08F94 Fibrocystin chr6 GO:0031224 Not Cancer Driver No 778 0.191 413 81 0.196 93
PRMT8 PRMT8 Q9NR22 Protein arginine N-methyltransferase 8 chr12 GO:0031224 Not Cancer Driver No 94 0.239 61 16 0.262 0
PRND PRND Q9UKY0 Prion-like protein doppel chr20 GO:0031224 Not Cancer Driver No 32 0.182 13 0 0.0 0
PRNP PRNP P04156 Major prion protein chr20 GO:0031224 Not Cancer Driver No 36 0.142 115 7 0.061 18
PRRT2_ENST00000645336 PRRT2 Q7Z6L0 Proline-rich transmembrane protein 2 chr16 GO:0031224 Not Cancer Driver No 45 0.132 268 32 0.119 7
PSEN1 PSEN1 P49768 Presenilin-1 chr14 GO:0031224 Not Cancer Driver No 61 0.131 134 21 0.157 96
PTPRD PTPRD P23468 Receptor-type tyrosine-protein phosphatase delta chr9 GO:0031224 Census, Compendium Yes 577 0.302 747 219 0.293 0
PTPRS PTPRS Q13332 Receptor-type tyrosine-protein phosphatase S chr19 GO:0031224 Not Cancer Driver No 250 0.128 829 111 0.134 0
RAB26 RAB26 Q9ULW5 Ras-related protein Rab-26 chr16 GO:0031224 Not Cancer Driver No 29 0.113 79 4 0.051 0
RAB27B RAB27B O00194 Ras-related protein Rab-27B chr18 GO:0031224 Not Cancer Driver No 42 0.193 43 9 0.209 0
RAB35 RAB35 Q15286 Ras-related protein Rab-35 chr12 GO:0031224 Not Cancer Driver No 25 0.124 25 2 0.08 0
RAB3A RAB3A P20336 Ras-related protein Rab-3A chr19 GO:0031224 Not Cancer Driver No 25 0.114 43 4 0.093 0
RAB3B RAB3B P20337 Ras-related protein Rab-3B chr1 GO:0031224 Not Cancer Driver No 36 0.164 25 6 0.24 0
RAB3C RAB3C Q96E17 Ras-related protein Rab-3C chr5 GO:0031224 Not Cancer Driver No 52 0.229 54 10 0.185 0
RAB5A RAB5A P20339 Ras-related protein Rab-5A chr3 GO:0031224 Not Cancer Driver No 32 0.149 65 15 0.231 0
RAB5B RAB5B P61020 Ras-related protein Rab-5B chr12 GO:0031224 Not Cancer Driver No 23 0.107 43 5 0.116 0
RAB7A RAB7A P51149 Ras-related protein Rab-7a chr3 GO:0031224 Not Cancer Driver No 27 0.13 11 0 0.0 4
RASA3 RASA3 Q14644 Ras GTPase-activating protein 3 chr13 GO:0031224 Not Cancer Driver No 118 0.141 101 19 0.188 0
RGS16 RGS16 O15492 Regulator of G-protein signaling 16 chr1 GO:0031224 Not Cancer Driver No 37 0.183 28 7 0.25 0
RGS7BP RGS7BP Q6MZT1 Regulator of G-protein signaling 7-binding protein chr5 GO:0031224 Not Cancer Driver No 49 0.191 166 31 0.187 0
RTBDN_ENST00000393233 RTBDN Q9BSG5 Retbindin chr19 GO:0031224 Not Cancer Driver No 21 0.092 70 8 0.114 0
RTN4R RTN4R Q9BZR6 Reticulon-4 receptor chr22 GO:0031224 Not Cancer Driver No 38 0.08 148 17 0.115 5
SCAMP1 SCAMP1 O15126 Secretory carrier-associated membrane protein 1 chr5 GO:0031224 Not Cancer Driver No 29 0.086 117 14 0.12 0
SCN10A SCN10A Q9Y5Y9 Sodium channel protein type 10 subunit alpha chr3 GO:0031224 Not Cancer Driver No 513 0.262 435 131 0.301 2
SCN2A_ENST00000637266 SCN2A Q99250 Sodium channel protein type 2 subunit alpha chr2 GO:0031224 Not Cancer Driver No 502 0.25 435 133 0.306 65
SLC12A2 SLC12A2 P55011 Solute carrier family 12 member 2 chr5 GO:0031224 Not Cancer Driver No 141 0.116 297 18 0.061 8
SLC15A1 SLC15A1 P46059 Solute carrier family 15 member 1 chr13 GO:0031224 Not Cancer Driver No 122 0.172 24 7 0.292 0
SLC15A2 SLC15A2 Q16348 Solute carrier family 15 member 2 chr3 GO:0031224 Not Cancer Driver No 153 0.21 37 7 0.189 0
SLC15A4 SLC15A4 Q8N697 Solute carrier family 15 member 4 chr12 GO:0031224 Not Cancer Driver No 66 0.114 23 4 0.174 0
SLC17A6 SLC17A6 Q9P2U8 Vesicular glutamate transporter 2 chr11 GO:0031224 Not Cancer Driver No 181 0.311 77 27 0.351 0
SLC17A7 SLC17A7 Q9P2U7 Vesicular glutamate transporter 1 chr19 GO:0031224 Not Cancer Driver No 79 0.141 80 21 0.263 0
SLC17A8 SLC17A8 Q8NDX2 Vesicular glutamate transporter 3 chr12 GO:0031224 Not Cancer Driver No 134 0.228 95 30 0.316 1
SLC1A2 SLC1A2 P43004 Excitatory amino acid transporter 2 chr11 GO:0031224 Not Cancer Driver No 77 0.134 81 7 0.086 3
SLC24A1 SLC24A1 O60721 Sodium/potassium/calcium exchanger 1 chr15 GO:0031224 Not Cancer Driver No 105 0.096 595 53 0.089 0
SLC24A2 SLC24A2 Q9UI40 Sodium/potassium/calcium exchanger 2 chr9 GO:0031224 Not Cancer Driver No 120 0.182 144 24 0.167 0
SLC24A3 SLC24A3 Q9HC58 Sodium/potassium/calcium exchanger 3 chr20 GO:0031224 Not Cancer Driver No 143 0.222 120 45 0.375 0
SLC24A4 SLC24A4 Q8NFF2 Sodium/potassium/calcium exchanger 4 chr14 GO:0031224 Not Cancer Driver No 121 0.195 85 14 0.165 2
SLC30A3 SLC30A3 Q99726 Zinc transporter 3 chr2 GO:0031224 Not Cancer Driver No 56 0.144 97 18 0.186 0
SLC32A1 SLC32A1 Q9H598 Vesicular inhibitory amino acid transporter chr20 GO:0031224 Not Cancer Driver No 138 0.263 82 19 0.232 0
SLC38A9 SLC38A9 Q8NBW4 Sodium-coupled neutral amino acid transporter 9 chr5 GO:0031224 Not Cancer Driver No 57 0.102 33 2 0.061 0
SLC46A3_ENST00000266943 SLC46A3 Q7Z3Q1 Solute carrier family 46 member 3 chr13 GO:0031224 Not Cancer Driver No 81 0.176 3 0 0.0 0
SLC4A4_ENST00000264485 SLC4A4 Q9Y6R1 Electrogenic sodium bicarbonate cotransporter 1 chr4 GO:0031224 Not Cancer Driver No 193 0.179 281 60 0.214 8
SLC6A11 SLC6A11 P48066 Sodium- and chloride-dependent GABA transporter 3 chr3 GO:0031224 Not Cancer Driver No 116 0.184 39 2 0.051 0
SLC6A17 SLC6A17 Q9H1V8 Sodium-dependent neutral amino acid transporter SLC6A17 chr1 GO:0031224 Not Cancer Driver No 119 0.164 67 10 0.149 2
SLC6A1_ENST00000643498 SLC6A1 P30531 Sodium- and chloride-dependent GABA transporter 1 chr3 GO:0031224 Not Cancer Driver No 119 0.199 24 9 0.375 4
SLC6A3 SLC6A3 Q01959 Sodium-dependent dopamine transporter chr5 GO:0031224 Not Cancer Driver No 150 0.242 31 8 0.258 2
SLC6A4_ENST00000401766 SLC6A4 P31645 Sodium-dependent serotonin transporter chr17 GO:0031224 Not Cancer Driver No 101 0.16 73 12 0.164 0
SLC6A5 SLC6A5 Q9Y345 Sodium- and chloride-dependent glycine transporter 2 chr11 GO:0031224 Not Cancer Driver No 181 0.227 169 38 0.225 7
SLC6A9 SLC6A9 P48067 Sodium- and chloride-dependent glycine transporter 1 chr1 GO:0031224 Not Cancer Driver No 102 0.144 65 12 0.185 1
SPAG4 SPAG4 Q9NPE6 Sperm-associated antigen 4 protein chr20 GO:0031224 Not Cancer Driver No 41 0.094 169 15 0.089 0
SPPL2A SPPL2A Q8TCT8 Signal peptide peptidase-like 2A chr15 GO:0031224 Not Cancer Driver No 55 0.106 3 0 0.0 0
SPPL2B SPPL2B Q8TCT7 Signal peptide peptidase-like 2B chr19 GO:0031224 Not Cancer Driver No 68 0.115 99 17 0.172 0
SPPL2C SPPL2C Q8IUH8 Signal peptide peptidase-like 2C chr17 GO:0031224 Not Cancer Driver No 110 0.161 216 45 0.208 0
SPPL3 SPPL3 Q8TCT6 Signal peptide peptidase-like 3 chr12 GO:0031224 Not Cancer Driver No 45 0.117 23 0 0.0 0
SPTA1_ENST00000368147 SPTA1 P02549 Spectrin alpha chain, erythrocytic 1 chr1 GO:0031224 Not Cancer Driver No 1046 0.432 707 294 0.416 21
SPTB_ENST00000389721 SPTB P11277 Spectrin beta chain, erythrocytic chr14 GO:0031224 Not Cancer Driver No 328 0.153 562 70 0.125 7
STX10 STX10 O60499 Syntaxin-10 chr19 GO:0031224 Not Cancer Driver No 29 0.116 77 7 0.091 0
STX12 STX12 Q86Y82 Syntaxin-12 chr1 GO:0031224 Not Cancer Driver No 21 0.076 156 9 0.058 0
STX1A STX1A Q16623 Syntaxin-1A chr7 GO:0031224 Not Cancer Driver No 35 0.122 136 11 0.081 0
STX6 STX6 O43752 Syntaxin-6 chr1 GO:0031224 Not Cancer Driver No 33 0.129 78 11 0.141 0
SUN1 SUN1 O94901 SUN domain-containing protein 1 chr7 GO:0031224 Not Cancer Driver No 109 0.139 246 26 0.106 0
SUN2_ENST00000405510 SUN2 Q9UH99 SUN domain-containing protein 2 chr22 GO:0031224 Not Cancer Driver No 74 0.103 214 18 0.084 0
SUN3_ENST00000395572 SUN3 Q8TAQ9 SUN domain-containing protein 3 chr7 GO:0031224 Not Cancer Driver No 65 0.182 51 12 0.235 0
SUN5 SUN5 Q8TC36 SUN domain-containing protein 5 chr20 GO:0031224 Not Cancer Driver No 82 0.216 70 10 0.143 3
SV2A SV2A Q7L0J3 Synaptic vesicle glycoprotein 2A chr1 GO:0031224 Not Cancer Driver No 134 0.181 150 31 0.207 0
SV2C SV2C Q496J9 Synaptic vesicle glycoprotein 2C chr5 GO:0031224 Not Cancer Driver No 155 0.213 134 33 0.246 0
SYN1 SYN1 P17600 Synapsin-1 chrX GO:0031224 Not Cancer Driver No 75 0.106 445 27 0.061 0
SYNE4 SYNE4 Q8N205 Nesprin-4 chr19 GO:0031224 Not Cancer Driver No 50 0.124 236 31 0.131 0
SYNGR1 SYNGR1 O43759 Synaptogyrin-1 chr22 GO:0031224 Not Cancer Driver No 26 0.112 48 5 0.104 0
SYP SYP P08247 Synaptophysin chrX GO:0031224 Not Cancer Driver No 36 0.115 93 8 0.086 1
SYPL1 SYPL1 Q16563 Synaptophysin-like protein 1 chr7 GO:0031224 Not Cancer Driver No 31 0.12 17 3 0.176 0
SYT1_ENST00000393240 SYT1 P21579 Synaptotagmin-1 chr12 GO:0031224 Not Cancer Driver No 104 0.246 103 36 0.35 5
SYT4 SYT4 Q9H2B2 Synaptotagmin-4 chr18 GO:0031224 Not Cancer Driver No 111 0.261 107 41 0.383 0
SYT5 SYT5 O00445 Synaptotagmin-5 chr19 GO:0031224 Not Cancer Driver No 60 0.155 110 11 0.1 0
SYT7_ENST00000263846 SYT7 O43581 Synaptotagmin-7 chr11 GO:0031224 Not Cancer Driver No 63 0.156 132 25 0.189 0
SYT9 SYT9 Q86SS6 Synaptotagmin-9 chr11 GO:0031224 Not Cancer Driver No 120 0.244 148 42 0.284 0
TAPBP_ENST00000434618 TAPBP O15533 Tapasin chr6 GO:0031224 Not Cancer Driver No 58 0.129 168 26 0.155 0
TGM1 TGM1 P22735 Protein-glutamine gamma-glutamyltransferase K chr14 GO:0031224 Not Cancer Driver No 118 0.144 230 37 0.161 65
THY1 THY1 P04216 Thy-1 membrane glycoprotein chr11 GO:0031224 Not Cancer Driver No 24 0.149 5 0 0.0 0
TM2D3 TM2D3 Q9BRN9 TM2 domain-containing protein 3 chr15 GO:0031224 Not Cancer Driver No 31 0.126 13 3 0.231 0
TMEM163 TMEM163 Q8TC26 Transmembrane protein 163 chr2 GO:0031224 Not Cancer Driver No 43 0.149 74 1 0.014 0
TMEM173 STING1 Q86WV6 Stimulator of interferon genes protein chr5 GO:0031224 Not Cancer Driver No 46 0.121 66 13 0.197 3
TMEM175 TMEM175 Q9BSA9 Endosomal/lysosomal potassium channel TMEM175 chr4 GO:0031224 Not Cancer Driver No 77 0.153 51 13 0.255 0
TMEM201 TMEM201 Q5SNT2 Transmembrane protein 201 chr1 GO:0031224 Not Cancer Driver No 50 0.075 241 18 0.075 0
TMEM43 TMEM43 Q9BTV4 Transmembrane protein 43 chr3 GO:0031224 Not Cancer Driver No 47 0.117 57 9 0.158 3
TRPM4 TRPM4 Q8TD43 Transient receptor potential cation channel subfamily M member 4 chr19 GO:0031224 Not Cancer Driver No 152 0.125 149 18 0.121 12
UPK1A_ENST00000222275 UPK1A O00322 Uroplakin-1a chr19 GO:0031224 Not Cancer Driver No 36 0.14 0 0 0.0 0
UPK1B UPK1B O75841 Uroplakin-1b chr3 GO:0031224 Not Cancer Driver No 33 0.127 13 3 0.231 0
UPK3A UPK3A O75631 Uroplakin-3a chr22 GO:0031224 Not Cancer Driver No 39 0.136 66 11 0.167 0
WFS1_ENST00000503569 WFS1 O76024 Wolframin chr4 GO:0031224 Not Cancer Driver No 105 0.118 203 10 0.049 39
ZDHHC9_ENST00000371064 ZDHHC9 Q9Y397 Palmitoyltransferase ZDHHC9 chrX GO:0031224 Not Cancer Driver No 52 0.143 84 6 0.071 2