Total number of protein in "GO:0031110" GO term: 87
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABL1_ENST00000318560 | ABL1 | P00519 | Tyrosine-protein kinase ABL1 | chr9 | GO:0031110 | Census, Compendium | Yes | 139 | 0.123 | 604 | 73 | 0.121 | 2 |
| AKAP9 | AKAP9 | Q99996 | A-kinase anchor protein 9 | chr7 | GO:0031110 | Census | Yes | 474 | 0.121 | 2281 | 268 | 0.117 | 1 |
| ANKRD53 | ANKRD53 | Q8N9V6 | Ankyrin repeat domain-containing protein 53 | chr2 | GO:0031110 | Not Cancer Driver | No | 57 | 0.108 | 252 | 21 | 0.083 | 0 |
| APC | APC | P25054 | Adenomatous polyposis coli protein | chr5 | GO:0031110 | Census, Compendium | Yes | 412 | 0.145 | 2406 | 345 | 0.143 | 22 |
| APC2_ENST00000233607 | APC2 | O95996 | Adenomatous polyposis coli protein 2 | chr19 | GO:0031110 | Not Cancer Driver | No | 117 | 0.051 | 1725 | 78 | 0.045 | 0 |
| ARHGEF2 | ARHGEF2 | Q92974 | Rho guanine nucleotide exchange factor 2 | chr1 | GO:0031110 | Not Cancer Driver | No | 146 | 0.148 | 450 | 70 | 0.156 | 0 |
| ARHGEF7 | ARHGEF7 | Q14155 | Rho guanine nucleotide exchange factor 7 | chr13 | GO:0031110 | Not Cancer Driver | No | 106 | 0.132 | 301 | 39 | 0.13 | 0 |
| ARL2 | ARL2 | P36404 | ADP-ribosylation factor-like protein 2 | chr11 | GO:0031110 | Not Cancer Driver | No | 19 | 0.103 | 0 | 0 | 0.0 | 1 |
| ARL3 | ARL3 | P36405 | ADP-ribosylation factor-like protein 3 | chr10 | GO:0031110 | Not Cancer Driver | No | 16 | 0.088 | 0 | 0 | 0.0 | 2 |
| ATXN7_ENST00000487717 | ATXN7 | O15265 | Ataxin-7 | chr3 | GO:0031110 | Not Cancer Driver | No | 95 | 0.107 | 797 | 82 | 0.103 | 0 |
| C16orf45 | BMERB1 | Q96MC5 | bMERB domain-containing protein 1 | chr16 | GO:0031110 | Not Cancer Driver | No | 32 | 0.157 | 102 | 16 | 0.157 | 0 |
| CAMSAP1 | CAMSAP1 | Q5T5Y3 | Calmodulin-regulated spectrin-associated protein 1 | chr9 | GO:0031110 | Not Cancer Driver | No | 208 | 0.13 | 1129 | 158 | 0.14 | 0 |
| CAMSAP2 | CAMSAP2 | Q08AD1 | Calmodulin-regulated spectrin-associated protein 2 | chr1 | GO:0031110 | Not Cancer Driver | No | 176 | 0.118 | 1025 | 127 | 0.124 | 0 |
| CAMSAP3_ENST00000160298 | CAMSAP3 | Q9P1Y5 | Calmodulin-regulated spectrin-associated protein 3 | chr19 | GO:0031110 | Not Cancer Driver | No | 132 | 0.106 | 889 | 81 | 0.091 | 0 |
| CAV3 | CAV3 | P56539 | Caveolin-3 | chr3 | GO:0031110 | Not Cancer Driver | No | 27 | 0.179 | 0 | 0 | 0.0 | 25 |
| CDH5 | CDH5 | P33151 | Cadherin-5 | chr16 | GO:0031110 | Not Cancer Driver | No | 144 | 0.184 | 305 | 55 | 0.18 | 0 |
| CDK5R1 | CDK5R1 | Q15078 | Cyclin-dependent kinase 5 activator 1 | chr17 | GO:0031110 | Not Cancer Driver | No | 35 | 0.114 | 103 | 16 | 0.155 | 0 |
| CDK5RAP2 | CDK5RAP2 | Q96SN8 | CDK5 regulatory subunit-associated protein 2 | chr9 | GO:0031110 | Not Cancer Driver | No | 217 | 0.115 | 1136 | 128 | 0.113 | 0 |
| CDKN1B | CDKN1B | P46527 | Cyclin-dependent kinase inhibitor 1B | chr12 | GO:0031110 | Census, Compendium | Yes | 19 | 0.096 | 198 | 19 | 0.096 | 0 |
| CIB1_ENST00000328649 | CIB1 | Q99828 | Calcium and integrin-binding protein 1 | chr15 | GO:0031110 | Not Cancer Driver | No | 24 | 0.126 | 6 | 1 | 0.167 | 0 |
| CKAP2 | CKAP2 | Q8WWK9 | Cytoskeleton-associated protein 2 | chr13 | GO:0031110 | Not Cancer Driver | No | 72 | 0.105 | 522 | 57 | 0.109 | 0 |
| CKAP5 | CKAP5 | Q14008 | Cytoskeleton-associated protein 5 | chr11 | GO:0031110 | Not Cancer Driver | No | 198 | 0.097 | 634 | 64 | 0.101 | 0 |
| CLASP1_ENST00000646274 | CLASP1 | Q7Z460 | CLIP-associating protein 1 | chr2 | GO:0031110 | Not Cancer Driver | No | 163 | 0.106 | 642 | 70 | 0.109 | 0 |
| CLASP2 | CLASP2 | O75122 | CLIP-associating protein 2 | chr3 | GO:0031110 | Not Cancer Driver | No | 158 | 0.122 | 676 | 94 | 0.139 | 0 |
| CLIP1 | CLIP1 | P30622 | CAP-Gly domain-containing linker protein 1 | chr12 | GO:0031110 | Census, Compendium | Yes | 184 | 0.128 | 1194 | 136 | 0.114 | 0 |
| CLIP3_ENST00000593074 | CLIP3 | Q96DZ5 | CAP-Gly domain-containing linker protein 3 | chr19 | GO:0031110 | Not Cancer Driver | No | 78 | 0.143 | 218 | 22 | 0.101 | 0 |
| DCTN1 | DCTN1 | Q14203 | Dynactin subunit 1 | chr2 | GO:0031110 | Census | Yes | 172 | 0.135 | 817 | 111 | 0.136 | 11 |
| DRG1 | DRG1 | Q9Y295 | Developmentally-regulated GTP-binding protein 1 | chr22 | GO:0031110 | Not Cancer Driver | No | 35 | 0.095 | 31 | 0 | 0.0 | 0 |
| DYRK1A_ENST00000644942 | DYRK1A | Q13627 | Dual specificity tyrosine-phosphorylation-regulated kinase 1A | chr21 | GO:0031110 | Not Cancer Driver | No | 135 | 0.177 | 447 | 73 | 0.163 | 0 |
| EML2_ENST00000245925 | EML2 | O95834 | Echinoderm microtubule-associated protein-like 2 | chr19 | GO:0031110 | Not Cancer Driver | No | 97 | 0.149 | 20 | 3 | 0.15 | 0 |
| FES | FES | P07332 | Tyrosine-protein kinase Fes/Fps | chr15 | GO:0031110 | Census | Yes | 103 | 0.125 | 245 | 34 | 0.139 | 0 |
| FGF13_ENST00000315930 | FGF13 | Q92913 | Fibroblast growth factor 13 | chrX | GO:0031110 | Not Cancer Driver | No | 70 | 0.286 | 96 | 33 | 0.344 | 2 |
| FKBP4 | FKBP4 | Q02790 | Peptidyl-prolyl cis-trans isomerase FKBP4 | chr12 | GO:0031110 | Not Cancer Driver | No | 46 | 0.1 | 134 | 12 | 0.09 | 0 |
| GAS2L1_ENST00000621062 | GAS2L1 | Q99501 | GAS2-like protein 1 | chr22 | GO:0031110 | Not Cancer Driver | No | 76 | 0.112 | 474 | 50 | 0.105 | 0 |
| GBA2 | GBA2 | Q9HCG7 | Non-lysosomal glucosylceramidase | chr9 | GO:0031110 | Not Cancer Driver | No | 96 | 0.104 | 157 | 12 | 0.076 | 3 |
| GIT1_ENST00000225394 | GIT1 | Q9Y2X7 | ARF GTPase-activating protein GIT1 | chr17 | GO:0031110 | Not Cancer Driver | No | 67 | 0.088 | 434 | 42 | 0.097 | 0 |
| HDAC6_ENST00000426196 | HDAC6 | Q9UBN7 | Histone deacetylase 6 | chrX | GO:0031110 | Not Cancer Driver | No | 178 | 0.147 | 409 | 59 | 0.144 | 0 |
| HDGFL3 | HDGFL3 | Q9Y3E1 | Hepatoma-derived growth factor-related protein 3 | chr15 | GO:0031110 | Not Cancer Driver | No | 25 | 0.123 | 163 | 18 | 0.11 | 0 |
| HSPA1A | HSPA1A | P0DMV8 | Heat shock 70 kDa protein 1A | chr6 | GO:0031110 | Not Cancer Driver | No | 24 | 0.037 | 200 | 13 | 0.065 | 0 |
| HSPA1B | HSPA1B | P0DMV9 | Heat shock 70 kDa protein 1B | chr6 | GO:0031110 | Not Cancer Driver | No | 15 | 0.023 | 200 | 5 | 0.025 | 0 |
| INPP5J | INPP5J | Q15735 | Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A | chr22 | GO:0031110 | Not Cancer Driver | No | 102 | 0.101 | 629 | 42 | 0.067 | 0 |
| KATNB1 | KATNB1 | Q9BVA0 | Katanin p80 WD40 repeat-containing subunit B1 | chr16 | GO:0031110 | Not Cancer Driver | No | 70 | 0.107 | 179 | 24 | 0.134 | 3 |
| MAP1A | MAP1A | P78559 | Microtubule-associated protein 1A | chr15 | GO:0031110 | Not Cancer Driver | No | 369 | 0.132 | 2443 | 311 | 0.127 | 0 |
| MAP1B | MAP1B | P46821 | Microtubule-associated protein 1B | chr5 | GO:0031110 | Not Cancer Driver | No | 332 | 0.135 | 1947 | 278 | 0.143 | 0 |
| MAP1S | MAP1S | Q66K74 | Microtubule-associated protein 1S | chr19 | GO:0031110 | Not Cancer Driver | No | 118 | 0.111 | 527 | 48 | 0.091 | 0 |
| MAP2 | MAP2 | P11137 | Microtubule-associated protein 2 | chr2 | GO:0031110 | Compendium | Yes | 367 | 0.201 | 1726 | 340 | 0.197 | 0 |
| MAP6D1 | MAP6D1 | Q9H9H5 | MAP6 domain-containing protein 1 | chr3 | GO:0031110 | Not Cancer Driver | No | 8 | 0.04 | 173 | 8 | 0.046 | 0 |
| MAPRE1 | MAPRE1 | Q15691 | Microtubule-associated protein RP/EB family member 1 | chr20 | GO:0031110 | Not Cancer Driver | No | 26 | 0.097 | 109 | 11 | 0.101 | 0 |
| MAPRE2 | MAPRE2 | Q15555 | Microtubule-associated protein RP/EB family member 2 | chr18 | GO:0031110 | Not Cancer Driver | No | 50 | 0.153 | 176 | 28 | 0.159 | 3 |
| MAPRE3 | MAPRE3 | Q9UPY8 | Microtubule-associated protein RP/EB family member 3 | chr2 | GO:0031110 | Not Cancer Driver | No | 37 | 0.132 | 120 | 16 | 0.133 | 0 |
| MAPT_ENST00000262410 | MAPT | P10636 | Microtubule-associated protein tau | chr17 | GO:0031110 | Not Cancer Driver | No | 128 | 0.169 | 750 | 126 | 0.168 | 18 |
| MECP2_ENST00000303391 | MECP2 | P51608 | Methyl-CpG-binding protein 2 | chrX | GO:0031110 | Not Cancer Driver | No | 75 | 0.154 | 483 | 74 | 0.153 | 46 |
| MET_ENST00000397752 | MET | P08581 | Hepatocyte growth factor receptor | chr7 | GO:0031110 | Census, Compendium | Yes | 226 | 0.163 | 62 | 15 | 0.242 | 19 |
| MID1 | MID1 | O15344 | E3 ubiquitin-protein ligase Midline-1 | chrX | GO:0031110 | Not Cancer Driver | No | 86 | 0.129 | 86 | 16 | 0.186 | 4 |
| MID1IP1_ENST00000336949 | MID1IP1 | Q9NPA3 | Mid1-interacting protein 1 | chrX | GO:0031110 | Not Cancer Driver | No | 23 | 0.126 | 83 | 6 | 0.072 | 0 |
| NAV3 | NAV3 | Q8IVL0 | Neuron navigator 3 | chr12 | GO:0031110 | Not Cancer Driver | No | 699 | 0.293 | 1823 | 548 | 0.301 | 0 |
| NIN | NIN | Q8N4C6 | Ninein | chr14 | GO:0031110 | Census, Compendium | Yes | 239 | 0.114 | 1392 | 164 | 0.118 | 2 |
| NUMA1 | NUMA1 | Q14980 | Nuclear mitotic apparatus protein 1 | chr11 | GO:0031110 | Census, Compendium | Yes | 234 | 0.111 | 1864 | 203 | 0.109 | 0 |
| OCLN | OCLN | Q16625 | Occludin | chr5 | GO:0031110 | Not Cancer Driver | No | 54 | 0.103 | 244 | 21 | 0.086 | 1 |
| PAK1_ENST00000356341 | PAK1 | Q13153 | Serine/threonine-protein kinase PAK 1 | chr11 | GO:0031110 | Not Cancer Driver | No | 57 | 0.105 | 299 | 30 | 0.1 | 2 |
| PRUNE1 | PRUNE1 | Q86TP1 | Exopolyphosphatase PRUNE1 | chr1 | GO:0031110 | Not Cancer Driver | No | 43 | 0.095 | 93 | 14 | 0.151 | 4 |
| PSRC1_ENST00000409138 | PSRC1 | Q6PGN9 | Proline/serine-rich coiled-coil protein 1 | chr1 | GO:0031110 | Not Cancer Driver | No | 30 | 0.083 | 361 | 30 | 0.083 | 0 |
| RAC1_ENST00000348035 | RAC1 | P63000 | Ras-related C3 botulinum toxin substrate 1 | chr7 | GO:0031110 | Census, Compendium | Yes | 66 | 0.344 | 2 | 1 | 0.5 | 6 |
| RANGRF | RANGRF | Q9HD47 | Ran guanine nucleotide release factor | chr17 | GO:0031110 | Not Cancer Driver | No | 10 | 0.054 | 42 | 5 | 0.119 | 0 |
| RPS3_ENST00000527446 | RPS3 | P23396 | 40S ribosomal protein S3 | chr11 | GO:0031110 | Not Cancer Driver | No | 22 | 0.091 | 48 | 4 | 0.083 | 0 |
| SKA1_ENST00000398452 | SKA1 | Q96BD8 | Spindle and kinetochore-associated protein 1 | chr18 | GO:0031110 | Not Cancer Driver | No | 23 | 0.09 | 74 | 7 | 0.095 | 0 |
| SKA2 | SKA2 | Q8WVK7 | Spindle and kinetochore-associated protein 2 | chr17 | GO:0031110 | Not Cancer Driver | No | 12 | 0.099 | 44 | 6 | 0.136 | 0 |
| SKA3 | SKA3 | Q8IX90 | Spindle and kinetochore-associated protein 3 | chr13 | GO:0031110 | Not Cancer Driver | No | 56 | 0.136 | 230 | 32 | 0.139 | 0 |
| SLAIN1_ENST00000466548 | SLAIN1 | Q8ND83 | SLAIN motif-containing protein 1 | chr13 | GO:0031110 | Not Cancer Driver | No | 62 | 0.109 | 485 | 58 | 0.12 | 0 |
| SLAIN2 | SLAIN2 | Q9P270 | SLAIN motif-containing protein 2 | chr4 | GO:0031110 | Not Cancer Driver | No | 62 | 0.107 | 562 | 60 | 0.107 | 0 |
| SLC39A12 | SLC39A12 | Q504Y0 | Zinc transporter ZIP12 | chr10 | GO:0031110 | Not Cancer Driver | No | 210 | 0.304 | 89 | 29 | 0.326 | 0 |
| SNCA_ENST00000506244 | SNCA | P37840 | Alpha-synuclein | chr4 | GO:0031110 | Not Cancer Driver | No | 21 | 0.15 | 107 | 13 | 0.121 | 5 |
| SPAST | SPAST | Q9UBP0 | Spastin | chr2 | GO:0031110 | Not Cancer Driver | No | 73 | 0.119 | 270 | 25 | 0.093 | 77 |
| SPEF1 | SPEF1 | Q9Y4P9 | Sperm flagellar protein 1 | chr20 | GO:0031110 | Not Cancer Driver | No | 19 | 0.081 | 89 | 5 | 0.056 | 0 |
| STMN1_ENST00000357865 | STMN1 | P16949 | Stathmin | chr1 | GO:0031110 | Not Cancer Driver | No | 15 | 0.101 | 149 | 15 | 0.101 | 0 |
| STMN2_ENST00000220876 | STMN2 | Q93045 | Stathmin-2 | chr8 | GO:0031110 | Not Cancer Driver | No | 34 | 0.19 | 122 | 23 | 0.189 | 0 |
| STMN3 | STMN3 | Q9NZ72 | Stathmin-3 | chr20 | GO:0031110 | Not Cancer Driver | No | 26 | 0.144 | 152 | 25 | 0.164 | 0 |
| STMN4_ENST00000265770 | STMN4 | Q9H169 | Stathmin-4 | chr8 | GO:0031110 | Not Cancer Driver | No | 43 | 0.228 | 112 | 24 | 0.214 | 0 |
| STMND1 | STMND1 | H3BQB6 | Stathmin domain-containing protein 1 | chr6 | GO:0031110 | Not Cancer Driver | No | 3 | 0.011 | 256 | 2 | 0.008 | 0 |
| TAOK1 | TAOK1 | Q7L7X3 | Serine/threonine-protein kinase TAO1 | chr17 | GO:0031110 | Not Cancer Driver | No | 116 | 0.116 | 601 | 59 | 0.098 | 0 |
| TBCD | TBCD | Q9BTW9 | Tubulin-specific chaperone D | chr17 | GO:0031110 | Not Cancer Driver | No | 156 | 0.131 | 60 | 9 | 0.15 | 11 |
| TOGARAM1_ENST00000361577 | TOGARAM1 | Q9Y4F4 | TOG array regulator of axonemal microtubules protein 1 | chr14 | GO:0031110 | Not Cancer Driver | No | 230 | 0.134 | 703 | 101 | 0.144 | 3 |
| TPX2 | TPX2 | Q9ULW0 | Targeting protein for Xklp2 | chr20 | GO:0031110 | Not Cancer Driver | No | 92 | 0.123 | 695 | 86 | 0.124 | 0 |
| TRIM54_ENST00000380075 | TRIM54 | Q9BYV2 | Tripartite motif-containing protein 54 | chr2 | GO:0031110 | Not Cancer Driver | No | 63 | 0.176 | 98 | 17 | 0.173 | 0 |
| TRPV4 | TRPV4 | Q9HBA0 | Transient receptor potential cation channel subfamily V member 4 | chr12 | GO:0031110 | Not Cancer Driver | No | 142 | 0.163 | 231 | 34 | 0.147 | 44 |
| TTBK2 | TTBK2 | Q6IQ55 | Tau-tubulin kinase 2 | chr15 | GO:0031110 | Not Cancer Driver | No | 151 | 0.121 | 848 | 107 | 0.126 | 0 |
| TUBB4A | TUBB4A | P04350 | Tubulin beta-4A chain | chr19 | GO:0031110 | Not Cancer Driver | No | 91 | 0.205 | 61 | 16 | 0.262 | 2 |