Total number of protein in "GO:0030971" GO term: 74
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACP4 | ACP4 | Q9BZG2 | Testicular acid phosphatase | chr19 | GO:0030971 | Not Cancer Driver | No | 66 | 0.155 | 28 | 7 | 0.25 | 3 |
| ALKAL1 | ALKAL1 | Q6UXT8 | ALK and LTK ligand 1 | chr8 | GO:0030971 | Not Cancer Driver | No | 18 | 0.14 | 49 | 3 | 0.061 | 0 |
| ALKAL2 | ALKAL2 | Q6UX46 | ALK and LTK ligand 2 | chr2 | GO:0030971 | Not Cancer Driver | No | 7 | 0.046 | 31 | 0 | 0.0 | 0 |
| ANGPT1 | ANGPT1 | Q15389 | Angiopoietin-1 | chr8 | GO:0030971 | Not Cancer Driver | No | 130 | 0.261 | 131 | 24 | 0.183 | 1 |
| ANGPT2 | ANGPT2 | O15123 | Angiopoietin-2 | chr8 | GO:0030971 | Not Cancer Driver | No | 63 | 0.127 | 96 | 10 | 0.104 | 1 |
| ANGPT4 | ANGPT4 | Q9Y264 | Angiopoietin-4 | chr20 | GO:0030971 | Not Cancer Driver | No | 104 | 0.207 | 150 | 32 | 0.213 | 0 |
| ARHGEF16 | ARHGEF16 | Q5VV41 | Rho guanine nucleotide exchange factor 16 | chr1 | GO:0030971 | Not Cancer Driver | No | 68 | 0.096 | 297 | 13 | 0.044 | 0 |
| ARTN_ENST00000372354 | ARTN | Q5T4W7 | Artemin | chr1 | GO:0030971 | Not Cancer Driver | No | 11 | 0.05 | 154 | 6 | 0.039 | 0 |
| BLNK | BLNK | Q8WV28 | B-cell linker protein | chr10 | GO:0030971 | Not Cancer Driver | No | 74 | 0.162 | 376 | 61 | 0.162 | 0 |
| CADM4 | CADM4 | Q8NFZ8 | Cell adhesion molecule 4 | chr19 | GO:0030971 | Not Cancer Driver | No | 48 | 0.124 | 94 | 9 | 0.096 | 0 |
| CBL | CBL | P22681 | E3 ubiquitin-protein ligase CBL | chr11 | GO:0030971 | Census, Compendium | Yes | 115 | 0.127 | 512 | 56 | 0.109 | 4 |
| CBLB | CBLB | Q13191 | E3 ubiquitin-protein ligase CBL-B | chr3 | GO:0030971 | Census | Yes | 160 | 0.163 | 562 | 104 | 0.185 | 0 |
| CBLC_ENST00000647358 | CBLC | Q9ULV8 | E3 ubiquitin-protein ligase CBL-C | chr19 | GO:0030971 | Census | Yes | 60 | 0.127 | 128 | 21 | 0.164 | 0 |
| CD2 | CD2 | P06729 | T-cell surface antigen CD2 | chr1 | GO:0030971 | Not Cancer Driver | No | 75 | 0.214 | 126 | 35 | 0.278 | 0 |
| CPNE3 | CPNE3 | O75131 | Copine-3 | chr8 | GO:0030971 | Not Cancer Driver | No | 79 | 0.147 | 33 | 5 | 0.152 | 0 |
| CRK | CRK | P46108 | Adapter molecule crk | chr17 | GO:0030971 | Not Cancer Driver | No | 30 | 0.099 | 197 | 23 | 0.117 | 0 |
| CRKL | CRKL | P46109 | Crk-like protein | chr22 | GO:0030971 | Not Cancer Driver | No | 38 | 0.125 | 160 | 25 | 0.156 | 0 |
| DAZAP2_ENST00000412716 | DAZAP2 | Q15038 | DAZ-associated protein 2 | chr12 | GO:0030971 | Not Cancer Driver | No | 17 | 0.101 | 68 | 7 | 0.103 | 0 |
| DOCK4 | DOCK4 | Q8N1I0 | Dedicator of cytokinesis protein 4 | chr7 | GO:0030971 | Not Cancer Driver | No | 331 | 0.168 | 397 | 80 | 0.202 | 0 |
| DOK2 | DOK2 | O60496 | Docking protein 2 | chr8 | GO:0030971 | Not Cancer Driver | No | 58 | 0.141 | 254 | 31 | 0.122 | 0 |
| DUSP3 | DUSP3 | P51452 | Dual specificity protein phosphatase 3 | chr17 | GO:0030971 | Not Cancer Driver | No | 21 | 0.114 | 4 | 1 | 0.25 | 0 |
| EIF3A | EIF3A | Q14152 | Eukaryotic translation initiation factor 3 subunit A | chr10 | GO:0030971 | Not Cancer Driver | No | 181 | 0.131 | 835 | 130 | 0.156 | 0 |
| ELMO2_ENST00000396391 | ELMO2 | Q96JJ3 | Engulfment and cell motility protein 2 | chr20 | GO:0030971 | Not Cancer Driver | No | 82 | 0.114 | 101 | 9 | 0.089 | 0 |
| FIZ1 | FIZ1 | Q96SL8 | Flt3-interacting zinc finger protein 1 | chr19 | GO:0030971 | Not Cancer Driver | No | 55 | 0.111 | 197 | 22 | 0.112 | 0 |
| FLT3LG_ENST00000600429 | FLT3LG | P49771 | Fms-related tyrosine kinase 3 ligand | chr19 | GO:0030971 | Not Cancer Driver | No | 27 | 0.115 | 39 | 4 | 0.103 | 0 |
| FNTA | FNTA | P49354 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | chr8 | GO:0030971 | Not Cancer Driver | No | 43 | 0.113 | 92 | 12 | 0.13 | 0 |
| FRS2 | FRS2 | Q8WU20 | Fibroblast growth factor receptor substrate 2 | chr12 | GO:0030971 | Not Cancer Driver | No | 69 | 0.136 | 415 | 58 | 0.14 | 0 |
| FRS3_ENST00000259748 | FRS3 | O43559 | Fibroblast growth factor receptor substrate 3 | chr6 | GO:0030971 | Not Cancer Driver | No | 77 | 0.157 | 388 | 58 | 0.149 | 0 |
| GAB2 | GAB2 | Q9UQC2 | GRB2-associated-binding protein 2 | chr11 | GO:0030971 | Not Cancer Driver | No | 85 | 0.126 | 537 | 73 | 0.136 | 0 |
| GAS6 | GAS6 | Q14393 | Growth arrest-specific protein 6 | chr13 | GO:0030971 | Not Cancer Driver | No | 82 | 0.121 | 42 | 6 | 0.143 | 0 |
| GDNF_ENST00000326524 | GDNF | P39905 | Glial cell line-derived neurotrophic factor | chr5 | GO:0030971 | Not Cancer Driver | No | 47 | 0.223 | 83 | 18 | 0.217 | 2 |
| GFRAL | GFRAL | Q6UXV0 | GDNF family receptor alpha-like | chr6 | GO:0030971 | Not Cancer Driver | No | 176 | 0.447 | 5 | 2 | 0.4 | 0 |
| GRAPL | GRAPL | Q8TC17 | GRB2-related adapter protein-like | chr17 | GO:0030971 | Not Cancer Driver | No | 0 | 0.0 | 26 | 0 | 0.0 | 0 |
| GRB14 | GRB14 | Q14449 | Growth factor receptor-bound protein 14 | chr2 | GO:0030971 | Not Cancer Driver | No | 83 | 0.154 | 117 | 11 | 0.094 | 0 |
| HYAL2_ENST00000357750 | HYAL2 | Q12891 | Hyaluronidase-2 | chr3 | GO:0030971 | Not Cancer Driver | No | 52 | 0.11 | 8 | 1 | 0.125 | 0 |
| IRS1 | IRS1 | P35568 | Insulin receptor substrate 1 | chr2 | GO:0030971 | Not Cancer Driver | No | 161 | 0.13 | 1072 | 133 | 0.124 | 2 |
| ITGAX_ENST00000268296 | ITGAX | P20702 | Integrin alpha-X | chr16 | GO:0030971 | Not Cancer Driver | No | 245 | 0.211 | 82 | 15 | 0.183 | 0 |
| LRP4 | LRP4 | O75096 | Low-density lipoprotein receptor-related protein 4 | chr11 | GO:0030971 | Not Cancer Driver | No | 233 | 0.122 | 265 | 28 | 0.106 | 11 |
| MAP3K7 | MAP3K7 | O43318 | Mitogen-activated protein kinase kinase kinase 7 | chr6 | GO:0030971 | Not Cancer Driver | No | 104 | 0.172 | 333 | 66 | 0.198 | 6 |
| MST1 | MST1 | P26927 | Hepatocyte growth factor-like protein | chr3 | GO:0030971 | Not Cancer Driver | No | 110 | 0.155 | 168 | 19 | 0.113 | 0 |
| MYOC | MYOC | Q99972 | Myocilin | chr1 | GO:0030971 | Not Cancer Driver | No | 92 | 0.183 | 196 | 43 | 0.219 | 58 |
| NCK1_ENST00000288986 | NCK1 | P16333 | Cytoplasmic protein NCK1 | chr3 | GO:0030971 | Not Cancer Driver | No | 48 | 0.127 | 111 | 17 | 0.153 | 0 |
| NCK2_ENST00000393349 | NCK2 | O43639 | Cytoplasmic protein NCK2 | chr2 | GO:0030971 | Not Cancer Driver | No | 89 | 0.234 | 88 | 19 | 0.216 | 0 |
| NRG1_ENST00000405005 | NRG1 | Q02297 | Pro-neuregulin-1, membrane-bound isoform | chr8 | GO:0030971 | Census, Compendium | Yes | 159 | 0.248 | 528 | 132 | 0.25 | 0 |
| NRG3_ENST00000404547 | NRG3 | P56975 | Pro-neuregulin-3, membrane-bound isoform | chr10 | GO:0030971 | Not Cancer Driver | No | 227 | 0.315 | 425 | 134 | 0.315 | 0 |
| NRTN | NRTN | Q99748 | Neurturin | chr19 | GO:0030971 | Not Cancer Driver | No | 7 | 0.036 | 26 | 0 | 0.0 | 0 |
| PCNA | PCNA | P12004 | Proliferating cell nuclear antigen | chr20 | GO:0030971 | Not Cancer Driver | No | 30 | 0.115 | 22 | 3 | 0.136 | 1 |
| PIK3R1 | PIK3R1 | P27986 | Phosphatidylinositol 3-kinase regulatory subunit alpha | chr5 | GO:0030971 | Census, Compendium | Yes | 154 | 0.213 | 268 | 61 | 0.228 | 2 |
| PIK3R2_ENST00000617130 | PIK3R2 | O00459 | Phosphatidylinositol 3-kinase regulatory subunit beta | chr19 | GO:0030971 | Not Cancer Driver | No | 96 | 0.132 | 418 | 47 | 0.112 | 3 |
| PITPNM1_ENST00000534749 | PITPNM1 | O00562 | Membrane-associated phosphatidylinositol transfer protein 1 | chr11 | GO:0030971 | Not Cancer Driver | No | 157 | 0.126 | 477 | 69 | 0.145 | 0 |
| PITPNM2 | PITPNM2 | Q9BZ72 | Membrane-associated phosphatidylinositol transfer protein 2 | chr12 | GO:0030971 | Not Cancer Driver | No | 160 | 0.119 | 535 | 62 | 0.116 | 0 |
| PITPNM3 | PITPNM3 | Q9BZ71 | Membrane-associated phosphatidylinositol transfer protein 3 | chr17 | GO:0030971 | Not Cancer Driver | No | 143 | 0.147 | 334 | 53 | 0.159 | 1 |
| PSPN | PSPN | O60542 | Persephin | chr19 | GO:0030971 | Not Cancer Driver | No | 9 | 0.058 | 13 | 1 | 0.077 | 0 |
| PTPN1 | PTPN1 | P18031 | Tyrosine-protein phosphatase non-receptor type 1 | chr20 | GO:0030971 | Not Cancer Driver | No | 49 | 0.113 | 140 | 25 | 0.179 | 0 |
| PTPN11_ENST00000351677 | PTPN11 | Q06124 | Tyrosine-protein phosphatase non-receptor type 11 | chr12 | GO:0030971 | Census, Compendium | Yes | 129 | 0.218 | 260 | 38 | 0.146 | 60 |
| PTPN14 | PTPN14 | Q15678 | Tyrosine-protein phosphatase non-receptor type 14 | chr1 | GO:0030971 | Compendium | Yes | 173 | 0.146 | 582 | 99 | 0.17 | 0 |
| PTPN2 | PTPN2 | P17706 | Tyrosine-protein phosphatase non-receptor type 2 | chr18 | GO:0030971 | Not Cancer Driver | No | 57 | 0.137 | 120 | 14 | 0.117 | 0 |
| RACK1 | RACK1 | P63244 | Receptor of activated protein C kinase 1 | chr5 | GO:0030971 | Not Cancer Driver | No | 34 | 0.107 | 13 | 0 | 0.0 | 0 |
| RNF41_ENST00000615206 | RNF41 | Q9H4P4 | E3 ubiquitin-protein ligase NRDP1 | chr12 | GO:0030971 | Not Cancer Driver | No | 44 | 0.139 | 33 | 2 | 0.061 | 0 |
| SH2B1 | SH2B1 | Q9NRF2 | SH2B adapter protein 1 | chr16 | GO:0030971 | Not Cancer Driver | No | 98 | 0.13 | 612 | 84 | 0.137 | 0 |
| SH2B3 | SH2B3 | Q9UQQ2 | SH2B adapter protein 3 | chr12 | GO:0030971 | Census, Compendium | Yes | 48 | 0.083 | 333 | 19 | 0.057 | 0 |
| SHC1_ENST00000368445 | SHC1 | P29353 | SHC-transforming protein 1 | chr1 | GO:0030971 | Not Cancer Driver | No | 84 | 0.144 | 397 | 58 | 0.146 | 0 |
| SHC2 | SHC2 | P98077 | SHC-transforming protein 2 | chr19 | GO:0030971 | Not Cancer Driver | No | 66 | 0.113 | 362 | 44 | 0.122 | 0 |
| SHC3 | SHC3 | Q92529 | SHC-transforming protein 3 | chr9 | GO:0030971 | Not Cancer Driver | No | 94 | 0.158 | 432 | 64 | 0.148 | 0 |
| SHC4 | SHC4 | Q6S5L8 | SHC-transforming protein 4 | chr15 | GO:0030971 | Not Cancer Driver | No | 74 | 0.117 | 325 | 44 | 0.135 | 0 |
| SOCS5 | SOCS5 | O75159 | Suppressor of cytokine signaling 5 | chr2 | GO:0030971 | Not Cancer Driver | No | 84 | 0.157 | 297 | 46 | 0.155 | 0 |
| SQSTM1 | SQSTM1 | Q13501 | Sequestosome-1 | chr5 | GO:0030971 | Not Cancer Driver | No | 54 | 0.123 | 267 | 32 | 0.12 | 30 |
| STAP1_ENST00000396225 | STAP1 | Q9ULZ2 | Signal-transducing adaptor protein 1 | chr4 | GO:0030971 | Not Cancer Driver | No | 66 | 0.224 | 103 | 18 | 0.175 | 0 |
| TOB1 | TOB1 | P50616 | Protein Tob1 | chr17 | GO:0030971 | Not Cancer Driver | No | 35 | 0.101 | 214 | 18 | 0.084 | 0 |
| TP53_ENST00000445888 | TP53 | P04637 | Cellular tumor antigen p53 | chr17 | GO:0030971 | Census, Compendium | Yes | 2891 | 7.356 | 282 | 1466 | 5.199 | 83 |
| TRADD | TRADD | Q15628 | Tumor necrosis factor receptor type 1-associated DEATH domain protein | chr16 | GO:0030971 | Not Cancer Driver | No | 26 | 0.083 | 74 | 5 | 0.068 | 0 |
| TRAT1 | TRAT1 | Q6PIZ9 | T-cell receptor-associated transmembrane adapter 1 | chr3 | GO:0030971 | Not Cancer Driver | No | 86 | 0.462 | 129 | 67 | 0.519 | 0 |
| YWHAG | YWHAG | P61981 | 14-3-3 protein gamma | chr7 | GO:0030971 | Not Cancer Driver | No | 26 | 0.105 | 77 | 9 | 0.117 | 2 |
| ZPR1 | ZPR1 | O75312 | Zinc finger protein ZPR1 | chr11 | GO:0030971 | Not Cancer Driver | No | 38 | 0.083 | 291 | 27 | 0.093 | 0 |