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Total number of protein in "GO:0030595" GO term:  122

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ADAM8 ADAM8 P78325 Disintegrin and metalloproteinase domain-containing protein 8 chr10 GO:0030595 Not Cancer Driver No 82 0.1 230 13 0.057 0
ALOX5 ALOX5 P09917 Polyunsaturated fatty acid 5-lipoxygenase chr10 GO:0030595 Not Cancer Driver No 129 0.191 16 2 0.125 0
ANO6_ENST00000320560 ANO6 Q4KMQ2 Anoctamin-6 chr12 GO:0030595 Not Cancer Driver No 134 0.147 80 11 0.138 0
ANXA1_ENST00000257497 ANXA1 P04083 Annexin A1 chr9 GO:0030595 Not Cancer Driver No 59 0.171 61 12 0.197 0
ARHGEF5 ARHGEF5 Q12774 Rho guanine nucleotide exchange factor 5 chr7 GO:0030595 Not Cancer Driver No 170 0.106 1141 127 0.111 0
BSG BSG P35613 Basigin chr19 GO:0030595 Not Cancer Driver No 43 0.112 123 17 0.138 0
C10orf99 GPR15L Q6UWK7 Protein GPR15L chr10 GO:0030595 Not Cancer Driver No 11 0.136 0 0 0.0 0
C5AR1 C5AR1 P21730 C5a anaphylatoxin chemotactic receptor 1 chr19 GO:0030595 Not Cancer Driver No 71 0.203 0 0 0.0 0
CCL1 CCL1 P22362 C-C motif chemokine 1 chr17 GO:0030595 Not Cancer Driver No 27 0.281 0 0 0.0 0
CCL11 CCL11 P51671 Eotaxin chr17 GO:0030595 Not Cancer Driver No 18 0.186 14 3 0.214 0
CCL13 CCL13 Q99616 C-C motif chemokine 13 chr17 GO:0030595 Not Cancer Driver No 15 0.153 1 0 0.0 0
CCL17_ENST00000616880 CCL17 Q92583 C-C motif chemokine 17 chr16 GO:0030595 Not Cancer Driver No 10 0.106 0 0 0.0 0
CCL19 CCL19 Q99731 C-C motif chemokine 19 chr9 GO:0030595 Not Cancer Driver No 10 0.102 7 0 0.0 0
CCL2 CCL2 P13500 C-C motif chemokine 2 chr17 GO:0030595 Not Cancer Driver No 20 0.202 15 5 0.333 0
CCL20 CCL20 P78556 C-C motif chemokine 20 chr2 GO:0030595 Not Cancer Driver No 16 0.167 0 0 0.0 0
CCL21 CCL21 O00585 C-C motif chemokine 21 chr9 GO:0030595 Not Cancer Driver No 14 0.104 59 6 0.102 0
CCL22 CCL22 O00626 C-C motif chemokine 22 chr16 GO:0030595 Not Cancer Driver No 19 0.204 0 0 0.0 0
CCL24_ENST00000222902 CCL24 O00175 C-C motif chemokine 24 chr7 GO:0030595 Not Cancer Driver No 25 0.21 23 3 0.13 0
CCL25 CCL25 O15444 C-C motif chemokine 25 chr19 GO:0030595 Not Cancer Driver No 20 0.133 26 6 0.231 0
CCL26_ENST00000005180 CCL26 Q9Y258 C-C motif chemokine 26 chr7 GO:0030595 Not Cancer Driver No 9 0.096 0 0 0.0 0
CCL7 CCL7 P80098 C-C motif chemokine 7 chr17 GO:0030595 Not Cancer Driver No 30 0.303 13 3 0.231 0
CCL8 CCL8 P80075 C-C motif chemokine 8 chr17 GO:0030595 Not Cancer Driver No 17 0.172 0 0 0.0 0
CCR1 CCR1 P32246 C-C chemokine receptor type 1 chr3 GO:0030595 Not Cancer Driver No 69 0.194 14 5 0.357 0
CCR2_ENST00000400888 CCR2 P41597 C-C chemokine receptor type 2 chr3 GO:0030595 Not Cancer Driver No 81 0.217 23 1 0.043 0
CCR5 CCR5 P51681 C-C chemokine receptor type 5 chr3 GO:0030595 Not Cancer Driver No 107 0.304 0 0 0.0 0
CCR6_ENST00000349984 CCR6 P51684 C-C chemokine receptor type 6 chr6 GO:0030595 Not Cancer Driver No 56 0.15 13 2 0.154 0
CCR7 CCR7 P32248 C-C chemokine receptor type 7 chr17 GO:0030595 Census, Compendium Yes 50 0.132 0 0 0.0 0
CH25H CH25H O95992 Cholesterol 25-hydroxylase chr10 GO:0030595 Not Cancer Driver No 37 0.136 0 0 0.0 0
CHGA CHGA P10645 Chromogranin-A chr14 GO:0030595 Not Cancer Driver No 46 0.101 421 44 0.105 0
CKLF CKLF Q9UBR5 Chemokine-like factor chr16 GO:0030595 Not Cancer Driver No 20 0.132 0 0 0.0 0
CNR2 CNR2 P34972 Cannabinoid receptor 2 chr1 GO:0030595 Not Cancer Driver No 57 0.158 21 4 0.19 0
CORO1A CORO1A P31146 Coronin-1A chr16 GO:0030595 Not Cancer Driver No 51 0.111 126 15 0.119 1
CSF3R_ENST00000361632 CSF3R Q99062 Granulocyte colony-stimulating factor receptor chr1 GO:0030595 Census, Compendium Yes 131 0.157 209 34 0.163 2
CTSG CTSG P08311 Cathepsin G chr14 GO:0030595 Not Cancer Driver No 65 0.255 80 29 0.362 0
CX3CL1 CX3CL1 P78423 Fractalkine chr16 GO:0030595 Not Cancer Driver No 66 0.166 259 44 0.17 0
CX3CR1_ENST00000542107 CX3CR1 P49238 CX3C chemokine receptor 1 chr3 GO:0030595 Not Cancer Driver No 80 0.225 0 0 0.0 0
CXADR CXADR P78310 Coxsackievirus and adenovirus receptor chr21 GO:0030595 Not Cancer Driver No 51 0.14 98 19 0.194 0
CXCL1 CXCL1 P09341 Growth-regulated alpha protein chr4 GO:0030595 Not Cancer Driver No 20 0.187 18 4 0.222 0
CXCL10 CXCL10 P02778 C-X-C motif chemokine 10 chr4 GO:0030595 Not Cancer Driver No 19 0.194 12 4 0.333 0
CXCL11 CXCL11 O14625 C-X-C motif chemokine 11 chr4 GO:0030595 Not Cancer Driver No 13 0.138 0 0 0.0 0
CXCL13 CXCL13 O43927 C-X-C motif chemokine 13 chr4 GO:0030595 Not Cancer Driver No 11 0.101 0 0 0.0 0
CXCL2 CXCL2 P19875 C-X-C motif chemokine 2 chr4 GO:0030595 Not Cancer Driver No 11 0.103 15 5 0.333 0
CXCL3 CXCL3 P19876 C-X-C motif chemokine 3 chr4 GO:0030595 Not Cancer Driver No 11 0.103 8 0 0.0 0
CXCL5 CXCL5 P42830 C-X-C motif chemokine 5 chr4 GO:0030595 Not Cancer Driver No 25 0.219 1 0 0.0 0
CXCL6 CXCL6 P80162 C-X-C motif chemokine 6 chr4 GO:0030595 Not Cancer Driver No 17 0.149 9 1 0.111 0
CXCL8 CXCL8 P10145 Interleukin-8 chr4 GO:0030595 Not Cancer Driver No 17 0.172 0 0 0.0 0
CXCL9 CXCL9 Q07325 C-X-C motif chemokine 9 chr4 GO:0030595 Not Cancer Driver No 32 0.256 38 16 0.421 0
CXCR1 CXCR1 P25024 C-X-C chemokine receptor type 1 chr2 GO:0030595 Not Cancer Driver No 71 0.203 0 0 0.0 0
CXCR2 CXCR2 P25025 C-X-C chemokine receptor type 2 chr2 GO:0030595 Not Cancer Driver No 87 0.242 8 0 0.0 0
CXCR4_ENST00000241393 CXCR4 P61073 C-X-C chemokine receptor type 4 chr2 GO:0030595 Census, Compendium Yes 62 0.176 5 1 0.2 0
CXCR5 CXCR5 P32302 C-X-C chemokine receptor type 5 chr11 GO:0030595 Not Cancer Driver No 41 0.11 0 0 0.0 0
CYP7B1 CYP7B1 O75881 Cytochrome P450 7B1 chr8 GO:0030595 Not Cancer Driver No 133 0.263 0 0 0.0 11
DEFB104B DEFB104B Q8WTQ1 Beta-defensin 104 chr8 GO:0030595 Not Cancer Driver No 1 0.014 0 0 0.0 0
EDN1 EDN1 P05305 Endothelin-1 chr6 GO:0030595 Not Cancer Driver No 37 0.175 97 20 0.206 3
EDN2 EDN2 P20800 Endothelin-2 chr1 GO:0030595 Not Cancer Driver No 21 0.118 87 13 0.149 0
EDN3_ENST00000371028 EDN3 P14138 Endothelin-3 chr20 GO:0030595 Not Cancer Driver No 69 0.29 140 44 0.314 3
FCER1G FCER1G P30273 High affinity immunoglobulin epsilon receptor subunit gamma chr1 GO:0030595 Not Cancer Driver No 10 0.116 13 2 0.154 0
FFAR2 FFAR2 O15552 Free fatty acid receptor 2 chr19 GO:0030595 Not Cancer Driver No 49 0.148 32 7 0.219 0
FLT1 FLT1 P17948 Vascular endothelial growth factor receptor 1 chr13 GO:0030595 Not Cancer Driver No 299 0.223 103 20 0.194 0
FOLR2 FOLR2 P14207 Folate receptor beta chr11 GO:0030595 Not Cancer Driver No 32 0.125 6 0 0.0 0
GAS6 GAS6 Q14393 Growth arrest-specific protein 6 chr13 GO:0030595 Not Cancer Driver No 82 0.121 42 6 0.143 0
GBF1 GBF1 Q92538 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 chr10 GO:0030595 Not Cancer Driver No 216 0.116 669 76 0.114 0
GPR183 GPR183 P32249 G-protein coupled receptor 183 chr13 GO:0030595 Not Cancer Driver No 53 0.147 25 3 0.12 0
HMGB1_ENST00000405805 HMGB1 P09429 High mobility group protein B1 chr13 GO:0030595 Not Cancer Driver No 25 0.116 203 20 0.099 0
HRH1_ENST00000438284 HRH1 P35367 Histamine H1 receptor chr3 GO:0030595 Not Cancer Driver No 96 0.197 122 26 0.213 0
HSD3B7 HSD3B7 Q9H2F3 3 beta-hydroxysteroid dehydrogenase type 7 chr16 GO:0030595 Not Cancer Driver No 43 0.117 27 5 0.185 2
IL10 IL10 P22301 Interleukin-10 chr1 GO:0030595 Not Cancer Driver No 19 0.107 23 1 0.043 0
IL16 IL16 Q14005 Pro-interleukin-16 chr15 GO:0030595 Not Cancer Driver No 216 0.162 959 151 0.157 0
IL1B IL1B P01584 Interleukin-1 beta chr2 GO:0030595 Not Cancer Driver No 39 0.145 16 3 0.188 0
IL6 IL6 P05231 Interleukin-6 chr7 GO:0030595 Not Cancer Driver No 35 0.165 58 7 0.121 0
IL6R IL6R P08887 Interleukin-6 receptor subunit alpha chr1 GO:0030595 Not Cancer Driver No 55 0.118 165 23 0.139 1
ITGA1 ITGA1 P56199 Integrin alpha-1 chr5 GO:0030595 Not Cancer Driver No 156 0.132 107 13 0.121 0
ITGA9 ITGA9 Q13797 Integrin alpha-9 chr3 GO:0030595 Not Cancer Driver No 137 0.132 70 14 0.2 0
ITGB2_ENST00000355153 ITGB2 P05107 Integrin beta-2 chr21 GO:0030595 Not Cancer Driver No 147 0.191 59 9 0.153 15
JAML JAML Q86YT9 Junctional adhesion molecule-like chr11 GO:0030595 Not Cancer Driver No 72 0.183 68 11 0.162 0
KIT KIT P10721 Mast/stem cell growth factor receptor Kit chr4 GO:0030595 Census, Compendium Yes 226 0.232 83 33 0.398 21
LBP LBP P18428 Lipopolysaccharide-binding protein chr20 GO:0030595 Not Cancer Driver No 84 0.175 6 0 0.0 0
LGALS3 LGALS3 P17931 Galectin-3 chr14 GO:0030595 Not Cancer Driver No 15 0.06 133 6 0.045 0
LYST LYST Q99698 Lysosomal-trafficking regulator chr1 GO:0030595 Not Cancer Driver No 465 0.122 608 87 0.143 4
MDK_ENST00000407067 MDK P21741 Midkine chr11 GO:0030595 Not Cancer Driver No 15 0.105 20 2 0.1 0
MSMP MSMP Q1L6U9 Prostate-associated microseminoprotein chr9 GO:0030595 Not Cancer Driver No 15 0.108 27 0 0.0 0
NCKAP1L NCKAP1L P55160 Nck-associated protein 1-like chr12 GO:0030595 Not Cancer Driver No 247 0.219 51 10 0.196 4
NINJ1 NINJ1 Q92982 Ninjurin-1 chr9 GO:0030595 Not Cancer Driver No 17 0.112 29 0 0.0 0
PDE4B PDE4B Q07343 cAMP-specific 3',5'-cyclic phosphodiesterase 4B chr1 GO:0030595 Not Cancer Driver No 119 0.162 363 42 0.116 0
PDGFB PDGFB P01127 Platelet-derived growth factor subunit B chr22 GO:0030595 Census Yes 37 0.154 99 22 0.222 2
PF4 PF4 P02776 Platelet factor 4 chr4 GO:0030595 Not Cancer Driver No 13 0.129 0 0 0.0 0
PF4V1 PF4V1 P10720 Platelet factor 4 variant chr4 GO:0030595 Not Cancer Driver No 18 0.173 6 2 0.333 0
PIK3CD PIK3CD O00329 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform chr1 GO:0030595 Not Cancer Driver No 140 0.134 60 13 0.217 1
PIK3CG PIK3CG P48736 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform chr7 GO:0030595 Not Cancer Driver No 318 0.289 121 39 0.322 0
PIKFYVE PIKFYVE Q9Y2I7 1-phosphatidylinositol 3-phosphate 5-kinase chr2 GO:0030595 Not Cancer Driver No 278 0.133 848 101 0.119 1
PIP5K1C_ENST00000335312 PIP5K1C O60331 Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma chr19 GO:0030595 Not Cancer Driver No 98 0.147 360 60 0.167 1
PLA2G1B PLA2G1B P04054 Phospholipase A2 chr12 GO:0030595 Not Cancer Driver No 17 0.115 0 0 0.0 0
PLEC PLEC Q15149 Plectin chr8 GO:0030595 Not Cancer Driver No 677 0.145 2130 272 0.128 2
PPBP PPBP P02775 Platelet basic protein chr4 GO:0030595 Not Cancer Driver No 30 0.234 21 8 0.381 0
PPIA PPIA P62937 Peptidyl-prolyl cis-trans isomerase A chr7 GO:0030595 Not Cancer Driver No 11 0.067 24 3 0.125 0
PPIB PPIB P23284 Peptidyl-prolyl cis-trans isomerase B chr15 GO:0030595 Not Cancer Driver No 28 0.13 16 1 0.062 1
PREX1 PREX1 Q8TCU6 Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein chr20 GO:0030595 Not Cancer Driver No 297 0.179 307 55 0.179 0
PTN PTN P21246 Pleiotrophin chr7 GO:0030595 Not Cancer Driver No 43 0.256 51 11 0.216 0
PTPRO PTPRO Q16827 Receptor-type tyrosine-protein phosphatase O chr12 GO:0030595 Not Cancer Driver No 204 0.168 137 34 0.248 0
RPS19_ENST00000600467 RPS19 P39019 40S ribosomal protein S19 chr19 GO:0030595 Not Cancer Driver No 15 0.103 61 3 0.049 23
S100A12 S100A12 P80511 Protein S100-A12 chr1 GO:0030595 Not Cancer Driver No 18 0.196 1 0 0.0 0
S100A8 S100A8 P05109 Protein S100-A8 chr1 GO:0030595 Not Cancer Driver No 22 0.237 8 4 0.5 0
S100A9 S100A9 P06702 Protein S100-A9 chr1 GO:0030595 Not Cancer Driver No 18 0.158 76 7 0.092 0
S1PR1 S1PR1 P21453 Sphingosine 1-phosphate receptor 1 chr1 GO:0030595 Not Cancer Driver No 86 0.225 29 6 0.207 0
SAA1 SAA1 P0DJI8 Serum amyloid A-1 protein chr11 GO:0030595 Not Cancer Driver No 23 0.189 25 5 0.2 0
SBDS SBDS Q9Y3A5 Ribosome maturation protein SBDS chr7 GO:0030595 Census Yes 28 0.112 12 1 0.083 2
SCG2 SCG2 P13521 Secretogranin-2 chr2 GO:0030595 Not Cancer Driver No 116 0.188 531 103 0.194 0
SLAMF1_ENST00000302035 SLAMF1 Q13291 Signaling lymphocytic activation molecule chr1 GO:0030595 Not Cancer Driver No 82 0.245 64 10 0.156 0
SLAMF8 SLAMF8 Q9P0V8 SLAM family member 8 chr1 GO:0030595 Not Cancer Driver No 63 0.221 20 2 0.1 0
SLC12A2 SLC12A2 P55011 Solute carrier family 12 member 2 chr5 GO:0030595 Not Cancer Driver No 141 0.116 297 18 0.061 8
SRP54 SRP54 P61011 Signal recognition particle 54 kDa protein chr14 GO:0030595 Not Cancer Driver No 53 0.105 115 13 0.113 7
SYK_ENST00000375746 SYK P43405 Tyrosine-protein kinase SYK chr9 GO:0030595 Census Yes 96 0.151 131 27 0.206 5
TGFB2_ENST00000366930 TGFB2 P61812 Transforming growth factor beta-2 proprotein chr1 GO:0030595 Not Cancer Driver No 63 0.152 47 8 0.17 3
TNFRSF11A TNFRSF11A Q9Y6Q6 Tumor necrosis factor receptor superfamily member 11A chr18 GO:0030595 Not Cancer Driver No 70 0.114 285 33 0.116 0
TNFSF11 TNFSF11 O14788 Tumor necrosis factor ligand superfamily member 11 chr13 GO:0030595 Not Cancer Driver No 52 0.164 56 1 0.018 1
TREM1 TREM1 Q9NP99 Triggering receptor expressed on myeloid cells 1 chr6 GO:0030595 Not Cancer Driver No 45 0.192 63 7 0.111 0
TRPM2_ENST00000397928 TRPM2 O94759 Transient receptor potential cation channel subfamily M member 2 chr21 GO:0030595 Not Cancer Driver No 286 0.19 266 44 0.165 0
TRPM4 TRPM4 Q8TD43 Transient receptor potential cation channel subfamily M member 4 chr19 GO:0030595 Not Cancer Driver No 152 0.125 149 18 0.121 12
VAV1 VAV1 P15498 Proto-oncogene vav chr19 GO:0030595 Census, Compendium Yes 165 0.195 113 19 0.168 0
VAV3 VAV3 Q9UKW4 Guanine nucleotide exchange factor VAV3 chr1 GO:0030595 Not Cancer Driver No 153 0.181 102 18 0.176 0
XCL1 XCL1 P47992 Lymphotactin chr1 GO:0030595 Not Cancer Driver No 28 0.246 35 11 0.314 0
XCL2 XCL2 Q9UBD3 Cytokine SCM-1 beta chr1 GO:0030595 Not Cancer Driver No 20 0.175 35 5 0.143 0