Total number of protein in "GO:0030514" GO term: 55
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABL1_ENST00000318560 | ABL1 | P00519 | Tyrosine-protein kinase ABL1 | chr9 | GO:0030514 | Census, Compendium | Yes | 139 | 0.123 | 604 | 73 | 0.121 | 2 |
| BAMBI | BAMBI | Q13145 | BMP and activin membrane-bound inhibitor homolog | chr10 | GO:0030514 | Not Cancer Driver | No | 42 | 0.162 | 31 | 7 | 0.226 | 0 |
| BMPER | BMPER | Q8N8U9 | BMP-binding endothelial regulator protein | chr7 | GO:0030514 | Not Cancer Driver | No | 196 | 0.286 | 0 | 0 | 0.0 | 1 |
| CER1 | CER1 | O95813 | Cerberus | chr9 | GO:0030514 | Not Cancer Driver | No | 70 | 0.262 | 119 | 27 | 0.227 | 0 |
| CHRD | CHRD | Q9H2X0 | Chordin | chr3 | GO:0030514 | Not Cancer Driver | No | 171 | 0.179 | 308 | 61 | 0.198 | 0 |
| CHRDL1_ENST00000394797 | CHRDL1 | Q9BU40 | Chordin-like protein 1 | chrX | GO:0030514 | Not Cancer Driver | No | 106 | 0.232 | 67 | 13 | 0.194 | 1 |
| CRIM1 | CRIM1 | Q9NZV1 | Cysteine-rich motor neuron 1 protein | chr2 | GO:0030514 | Not Cancer Driver | No | 133 | 0.128 | 35 | 4 | 0.114 | 0 |
| CTDSPL2 | CTDSPL2 | Q05D32 | CTD small phosphatase-like protein 2 | chr15 | GO:0030514 | Not Cancer Driver | No | 47 | 0.101 | 256 | 27 | 0.105 | 0 |
| DAND5 | DAND5 | Q8N907 | DAN domain family member 5 | chr19 | GO:0030514 | Not Cancer Driver | No | 32 | 0.169 | 26 | 3 | 0.115 | 0 |
| DKK1 | DKK1 | O94907 | Dickkopf-related protein 1 | chr10 | GO:0030514 | Not Cancer Driver | No | 58 | 0.218 | 47 | 8 | 0.17 | 0 |
| DLX1 | DLX1 | P56177 | Homeobox protein DLX-1 | chr2 | GO:0030514 | Not Cancer Driver | No | 25 | 0.098 | 183 | 21 | 0.115 | 0 |
| FBN1 | FBN1 | P35555 | Fibrillin-1 | chr15 | GO:0030514 | Not Cancer Driver | No | 466 | 0.162 | 110 | 16 | 0.145 | 360 |
| FSTL3 | FSTL3 | O95633 | Follistatin-related protein 3 | chr19 | GO:0030514 | Census | Yes | 17 | 0.065 | 28 | 2 | 0.071 | 0 |
| FZD1 | FZD1 | Q9UP38 | Frizzled-1 | chr7 | GO:0030514 | Not Cancer Driver | No | 78 | 0.121 | 133 | 2 | 0.015 | 0 |
| GDF3 | GDF3 | Q9NR23 | Growth/differentiation factor 3 | chr12 | GO:0030514 | Not Cancer Driver | No | 79 | 0.217 | 3 | 3 | 1.0 | 5 |
| GREM1 | GREM1 | O60565 | Gremlin-1 | chr15 | GO:0030514 | Not Cancer Driver | No | 25 | 0.136 | 77 | 12 | 0.156 | 0 |
| GREM2 | GREM2 | Q9H772 | Gremlin-2 | chr1 | GO:0030514 | Not Cancer Driver | No | 54 | 0.321 | 22 | 9 | 0.409 | 3 |
| HIPK2 | HIPK2 | Q9H2X6 | Homeodomain-interacting protein kinase 2 | chr7 | GO:0030514 | Not Cancer Driver | No | 154 | 0.129 | 686 | 96 | 0.14 | 0 |
| HJV | HJV | Q6ZVN8 | Hemojuvelin | chr1 | GO:0030514 | Not Cancer Driver | No | 75 | 0.176 | 117 | 27 | 0.231 | 14 |
| HTRA1 | HTRA1 | Q92743 | Serine protease HTRA1 | chr10 | GO:0030514 | Not Cancer Driver | No | 77 | 0.16 | 40 | 9 | 0.225 | 11 |
| HTRA3 | HTRA3 | P83110 | Serine protease HTRA3 | chr4 | GO:0030514 | Not Cancer Driver | No | 64 | 0.141 | 57 | 11 | 0.193 | 0 |
| LEMD2_ENST00000614475 | LEMD2 | Q8NC56 | LEM domain-containing protein 2 | chr6 | GO:0030514 | Not Cancer Driver | No | 44 | 0.087 | 211 | 4 | 0.019 | 2 |
| LEMD3 | LEMD3 | Q9Y2U8 | Inner nuclear membrane protein Man1 | chr12 | GO:0030514 | Not Cancer Driver | No | 78 | 0.086 | 509 | 33 | 0.065 | 0 |
| LRP2 | LRP2 | P98164 | Low-density lipoprotein receptor-related protein 2 | chr2 | GO:0030514 | Not Cancer Driver | No | 998 | 0.214 | 209 | 40 | 0.191 | 1 |
| NBL1_ENST00000602662 | NBL1 | P41271 | Neuroblastoma suppressor of tumorigenicity 1 | chr1 | GO:0030514 | Not Cancer Driver | No | 18 | 0.099 | 64 | 4 | 0.062 | 0 |
| NOG | NOG | Q13253 | Noggin | chr17 | GO:0030514 | Not Cancer Driver | No | 22 | 0.095 | 86 | 9 | 0.105 | 20 |
| NOTCH1 | NOTCH1 | P46531 | Neurogenic locus notch homolog protein 1 | chr9 | GO:0030514 | Census, Compendium | Yes | 363 | 0.142 | 686 | 87 | 0.127 | 3 |
| PPARG | PPARG | P37231 | Peroxisome proliferator-activated receptor gamma | chr3 | GO:0030514 | Census | Yes | 72 | 0.143 | 44 | 4 | 0.091 | 3 |
| PPM1A_ENST00000395076 | PPM1A | P35813 | Protein phosphatase 1A | chr14 | GO:0030514 | Not Cancer Driver | No | 60 | 0.157 | 134 | 24 | 0.179 | 0 |
| RBPMS2 | RBPMS2 | Q6ZRY4 | RNA-binding protein with multiple splicing 2 | chr15 | GO:0030514 | Not Cancer Driver | No | 24 | 0.115 | 55 | 4 | 0.073 | 0 |
| SFRP1 | SFRP1 | Q8N474 | Secreted frizzled-related protein 1 | chr8 | GO:0030514 | Not Cancer Driver | No | 40 | 0.127 | 39 | 7 | 0.179 | 0 |
| SFRP2 | SFRP2 | Q96HF1 | Secreted frizzled-related protein 2 | chr4 | GO:0030514 | Not Cancer Driver | No | 47 | 0.159 | 1 | 0 | 0.0 | 0 |
| SKI | SKI | P12755 | Ski oncogene | chr1 | GO:0030514 | Census | Yes | 44 | 0.06 | 432 | 26 | 0.06 | 14 |
| SKIL_ENST00000259119 | SKIL | P12757 | Ski-like protein | chr3 | GO:0030514 | Not Cancer Driver | No | 77 | 0.113 | 356 | 32 | 0.09 | 0 |
| SKOR1_ENST00000380035 | SKOR1 | P84550 | SKI family transcriptional corepressor 1 | chr15 | GO:0030514 | Not Cancer Driver | No | 104 | 0.108 | 682 | 47 | 0.069 | 0 |
| SKOR2 | SKOR2 | Q2VWA4 | SKI family transcriptional corepressor 2 | chr18 | GO:0030514 | Not Cancer Driver | No | 20 | 0.02 | 640 | 8 | 0.013 | 0 |
| SMAD6 | SMAD6 | O43541 | Mothers against decapentaplegic homolog 6 | chr15 | GO:0030514 | Not Cancer Driver | No | 38 | 0.077 | 248 | 7 | 0.028 | 7 |
| SMAD7 | SMAD7 | O15105 | Mothers against decapentaplegic homolog 7 | chr18 | GO:0030514 | Not Cancer Driver | No | 40 | 0.094 | 139 | 0 | 0.0 | 0 |
| SMURF1 | SMURF1 | Q9HCE7 | E3 ubiquitin-protein ligase SMURF1 | chr7 | GO:0030514 | Not Cancer Driver | No | 89 | 0.118 | 256 | 31 | 0.121 | 0 |
| SMURF2 | SMURF2 | Q9HAU4 | E3 ubiquitin-protein ligase SMURF2 | chr17 | GO:0030514 | Not Cancer Driver | No | 87 | 0.116 | 242 | 28 | 0.116 | 0 |
| SORL1 | SORL1 | Q92673 | Sortilin-related receptor | chr11 | GO:0030514 | Not Cancer Driver | No | 374 | 0.169 | 87 | 10 | 0.115 | 0 |
| SOST | SOST | Q9BQB4 | Sclerostin | chr17 | GO:0030514 | Not Cancer Driver | No | 30 | 0.141 | 90 | 12 | 0.133 | 3 |
| SOSTDC1 | SOSTDC1 | Q6X4U4 | Sclerostin domain-containing protein 1 | chr7 | GO:0030514 | Not Cancer Driver | No | 22 | 0.107 | 72 | 3 | 0.042 | 0 |
| SPART_ENST00000355182 | SPART | Q8N0X7 | Spartin | chr13 | GO:0030514 | Not Cancer Driver | No | 112 | 0.168 | 396 | 68 | 0.172 | 1 |
| TMPRSS6_ENST00000346753 | TMPRSS6 | Q8IU80 | Transmembrane protease serine 6 | chr22 | GO:0030514 | Not Cancer Driver | No | 125 | 0.154 | 36 | 7 | 0.194 | 25 |
| TNFAIP6 | TNFAIP6 | P98066 | Tumor necrosis factor-inducible gene 6 protein | chr2 | GO:0030514 | Not Cancer Driver | No | 62 | 0.224 | 13 | 5 | 0.385 | 0 |
| TOB1 | TOB1 | P50616 | Protein Tob1 | chr17 | GO:0030514 | Not Cancer Driver | No | 35 | 0.101 | 214 | 18 | 0.084 | 0 |
| TRIM33 | TRIM33 | Q9UPN9 | E3 ubiquitin-protein ligase TRIM33 | chr1 | GO:0030514 | Census, Compendium | Yes | 110 | 0.098 | 617 | 51 | 0.083 | 0 |
| TWSG1 | TWSG1 | Q9GZX9 | Twisted gastrulation protein homolog 1 | chr18 | GO:0030514 | Not Cancer Driver | No | 27 | 0.121 | 19 | 3 | 0.158 | 0 |
| UBE2D1 | UBE2D1 | P51668 | Ubiquitin-conjugating enzyme E2 D1 | chr10 | GO:0030514 | Not Cancer Driver | No | 13 | 0.088 | 14 | 0 | 0.0 | 0 |
| UBE2D3_ENST00000394801 | UBE2D3 | P61077 | Ubiquitin-conjugating enzyme E2 D3 | chr4 | GO:0030514 | Not Cancer Driver | No | 21 | 0.143 | 13 | 4 | 0.308 | 0 |
| VWC2 | VWC2 | Q2TAL6 | Brorin | chr7 | GO:0030514 | Not Cancer Driver | No | 51 | 0.157 | 127 | 7 | 0.055 | 0 |
| VWC2L | VWC2L | B2RUY7 | von Willebrand factor C domain-containing protein 2-like | chr2 | GO:0030514 | Not Cancer Driver | No | 75 | 0.338 | 10 | 4 | 0.4 | 0 |
| WNT1 | WNT1 | P04628 | Proto-oncogene Wnt-1 | chr12 | GO:0030514 | Not Cancer Driver | No | 29 | 0.078 | 25 | 0 | 0.0 | 8 |
| WNT5A_ENST00000474267 | WNT5A | P41221 | Protein Wnt-5a | chr3 | GO:0030514 | Not Cancer Driver | No | 66 | 0.174 | 0 | 0 | 0.0 | 2 |