Total number of protein in "GO:0030512" GO term: 74
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ADAM17 | ADAM17 | P78536 | Disintegrin and metalloproteinase domain-containing protein 17 | chr2 | GO:0030512 | Not Cancer Driver | No | 80 | 0.097 | 182 | 17 | 0.093 | 0 |
| ADAMTSL2_ENST00000393060 | ADAMTSL2 | Q86TH1 | ADAMTS-like protein 2 | chr9 | GO:0030512 | Not Cancer Driver | No | 42 | 0.044 | 234 | 5 | 0.021 | 14 |
| ASPN | ASPN | Q9BXN1 | Asporin | chr9 | GO:0030512 | Not Cancer Driver | No | 40 | 0.105 | 32 | 9 | 0.281 | 0 |
| BAMBI | BAMBI | Q13145 | BMP and activin membrane-bound inhibitor homolog | chr10 | GO:0030512 | Not Cancer Driver | No | 42 | 0.162 | 31 | 7 | 0.226 | 0 |
| BCL9L | BCL9L | Q86UU0 | B-cell CLL/lymphoma 9-like protein | chr11 | GO:0030512 | Census, Compendium | Yes | 200 | 0.133 | 1495 | 200 | 0.134 | 0 |
| BMP2 | BMP2 | P12643 | Bone morphogenetic protein 2 | chr20 | GO:0030512 | Not Cancer Driver | No | 73 | 0.184 | 139 | 26 | 0.187 | 0 |
| CAV1 | CAV1 | Q03135 | Caveolin-1 | chr7 | GO:0030512 | Not Cancer Driver | No | 30 | 0.169 | 2 | 0 | 0.0 | 0 |
| CAV2 | CAV2 | P51636 | Caveolin-2 | chr7 | GO:0030512 | Not Cancer Driver | No | 20 | 0.123 | 5 | 2 | 0.4 | 0 |
| CD109 | CD109 | Q6YHK3 | CD109 antigen | chr6 | GO:0030512 | Not Cancer Driver | No | 204 | 0.141 | 54 | 11 | 0.204 | 0 |
| CHST11 | CHST11 | Q9NPF2 | Carbohydrate sulfotransferase 11 | chr12 | GO:0030512 | Census | Yes | 69 | 0.196 | 45 | 11 | 0.244 | 0 |
| CIDEA | CIDEA | O60543 | Cell death activator CIDE-A | chr18 | GO:0030512 | Not Cancer Driver | No | 43 | 0.196 | 32 | 3 | 0.094 | 0 |
| DAND5 | DAND5 | Q8N907 | DAN domain family member 5 | chr19 | GO:0030512 | Not Cancer Driver | No | 32 | 0.169 | 26 | 3 | 0.115 | 0 |
| DNM2_ENST00000355667 | DNM2 | P50570 | Dynamin-2 | chr19 | GO:0030512 | Census | Yes | 138 | 0.159 | 270 | 43 | 0.159 | 22 |
| EID2 | EID2 | Q8N6I1 | EP300-interacting inhibitor of differentiation 2 | chr19 | GO:0030512 | Not Cancer Driver | No | 18 | 0.076 | 136 | 8 | 0.059 | 0 |
| EMILIN1 | EMILIN1 | Q9Y6C2 | EMILIN-1 | chr2 | GO:0030512 | Not Cancer Driver | No | 125 | 0.123 | 669 | 69 | 0.103 | 0 |
| FAM89B | FAM89B | Q8N5H3 | Leucine repeat adapter protein 25 | chr11 | GO:0030512 | Not Cancer Driver | No | 14 | 0.074 | 108 | 11 | 0.102 | 0 |
| FBN1 | FBN1 | P35555 | Fibrillin-1 | chr15 | GO:0030512 | Not Cancer Driver | No | 466 | 0.162 | 110 | 16 | 0.145 | 360 |
| FBN2_ENST00000262464 | FBN2 | P35556 | Fibrillin-2 | chr5 | GO:0030512 | Compendium | Yes | 607 | 0.208 | 135 | 24 | 0.178 | 30 |
| FKBP1A | FKBP1A | P62942 | Peptidyl-prolyl cis-trans isomerase FKBP1A | chr20 | GO:0030512 | Not Cancer Driver | No | 15 | 0.139 | 39 | 7 | 0.179 | 0 |
| GLG1_ENST00000422840 | GLG1 | Q92896 | Golgi apparatus protein 1 | chr16 | GO:0030512 | Not Cancer Driver | No | 134 | 0.114 | 103 | 7 | 0.068 | 0 |
| HSPA1A | HSPA1A | P0DMV8 | Heat shock 70 kDa protein 1A | chr6 | GO:0030512 | Not Cancer Driver | No | 24 | 0.037 | 200 | 13 | 0.065 | 0 |
| HSPA5 | HSPA5 | P11021 | Endoplasmic reticulum chaperone BiP | chr9 | GO:0030512 | Not Cancer Driver | No | 73 | 0.112 | 282 | 35 | 0.124 | 0 |
| HTRA1 | HTRA1 | Q92743 | Serine protease HTRA1 | chr10 | GO:0030512 | Not Cancer Driver | No | 77 | 0.16 | 40 | 9 | 0.225 | 11 |
| HTRA3 | HTRA3 | P83110 | Serine protease HTRA3 | chr4 | GO:0030512 | Not Cancer Driver | No | 64 | 0.141 | 57 | 11 | 0.193 | 0 |
| HTRA4 | HTRA4 | P83105 | Serine protease HTRA4 | chr8 | GO:0030512 | Not Cancer Driver | No | 57 | 0.12 | 15 | 0 | 0.0 | 0 |
| IL17RD | IL17RD | Q8NFM7 | Interleukin-17 receptor D | chr3 | GO:0030512 | Not Cancer Driver | No | 98 | 0.133 | 177 | 17 | 0.096 | 7 |
| LDLRAD4 | LDLRAD4 | O15165 | Low-density lipoprotein receptor class A domain-containing protein 4 | chr18 | GO:0030512 | Not Cancer Driver | No | 66 | 0.216 | 191 | 39 | 0.204 | 0 |
| LEMD3 | LEMD3 | Q9Y2U8 | Inner nuclear membrane protein Man1 | chr12 | GO:0030512 | Not Cancer Driver | No | 78 | 0.086 | 509 | 33 | 0.065 | 0 |
| LTBP1 | LTBP1 | Q14766 | Latent-transforming growth factor beta-binding protein 1 | chr2 | GO:0030512 | Not Cancer Driver | No | 300 | 0.174 | 518 | 78 | 0.151 | 0 |
| MTMR4 | MTMR4 | Q9NYA4 | Myotubularin-related protein 4 | chr17 | GO:0030512 | Not Cancer Driver | No | 147 | 0.123 | 474 | 59 | 0.124 | 0 |
| NKX2-1_ENST00000518149 | NKX2-1 | P43699 | Homeobox protein Nkx-2.1 | chr14 | GO:0030512 | Census, Compendium | Yes | 41 | 0.111 | 334 | 39 | 0.117 | 7 |
| NRROS | NRROS | Q86YC3 | Transforming growth factor beta activator LRRC33 | chr3 | GO:0030512 | Not Cancer Driver | No | 109 | 0.158 | 8 | 1 | 0.125 | 0 |
| ONECUT1 | ONECUT1 | Q9UBC0 | Hepatocyte nuclear factor 6 | chr15 | GO:0030512 | Not Cancer Driver | No | 78 | 0.168 | 405 | 65 | 0.16 | 0 |
| ONECUT2 | ONECUT2 | O95948 | One cut domain family member 2 | chr18 | GO:0030512 | Not Cancer Driver | No | 76 | 0.151 | 408 | 54 | 0.132 | 0 |
| PBLD | PBLD | P30039 | Phenazine biosynthesis-like domain-containing protein | chr10 | GO:0030512 | Not Cancer Driver | No | 41 | 0.142 | 5 | 1 | 0.2 | 0 |
| PDPK1 | PDPK1 | O15530 | 3-phosphoinositide-dependent protein kinase 1 | chr16 | GO:0030512 | Not Cancer Driver | No | 33 | 0.059 | 121 | 12 | 0.099 | 0 |
| PEG10_ENST00000617526 | PEG10 | Q86TG7 | Retrotransposon-derived protein PEG10 | chr7 | GO:0030512 | Not Cancer Driver | No | 94 | 0.133 | 246 | 47 | 0.191 | 0 |
| PIN1 | PIN1 | Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | chr19 | GO:0030512 | Not Cancer Driver | No | 17 | 0.104 | 115 | 12 | 0.104 | 0 |
| PMEPA1 | PMEPA1 | Q969W9 | Protein TMEPAI | chr20 | GO:0030512 | Not Cancer Driver | No | 45 | 0.157 | 196 | 34 | 0.173 | 0 |
| PPARA_ENST00000402126 | PPARA | Q07869 | Peroxisome proliferator-activated receptor alpha | chr22 | GO:0030512 | Not Cancer Driver | No | 63 | 0.135 | 68 | 9 | 0.132 | 0 |
| PPARG | PPARG | P37231 | Peroxisome proliferator-activated receptor gamma | chr3 | GO:0030512 | Census | Yes | 72 | 0.143 | 44 | 4 | 0.091 | 3 |
| PPM1A_ENST00000395076 | PPM1A | P35813 | Protein phosphatase 1A | chr14 | GO:0030512 | Not Cancer Driver | No | 60 | 0.157 | 134 | 24 | 0.179 | 0 |
| PRDM16 | PRDM16 | Q9HAZ2 | Histone-lysine N-methyltransferase PRDM16 | chr1 | GO:0030512 | Census | Yes | 254 | 0.199 | 830 | 152 | 0.183 | 1 |
| RASL11B | RASL11B | Q9BPW5 | Ras-like protein family member 11B | chr4 | GO:0030512 | Not Cancer Driver | No | 24 | 0.097 | 33 | 4 | 0.121 | 0 |
| SIRT1 | SIRT1 | Q96EB6 | NAD-dependent protein deacetylase sirtuin-1 | chr10 | GO:0030512 | Not Cancer Driver | No | 70 | 0.094 | 435 | 31 | 0.071 | 0 |
| SKI | SKI | P12755 | Ski oncogene | chr1 | GO:0030512 | Census | Yes | 44 | 0.06 | 432 | 26 | 0.06 | 14 |
| SKIL_ENST00000259119 | SKIL | P12757 | Ski-like protein | chr3 | GO:0030512 | Not Cancer Driver | No | 77 | 0.113 | 356 | 32 | 0.09 | 0 |
| SKOR2 | SKOR2 | Q2VWA4 | SKI family transcriptional corepressor 2 | chr18 | GO:0030512 | Not Cancer Driver | No | 20 | 0.02 | 640 | 8 | 0.013 | 0 |
| SLC2A10 | SLC2A10 | O95528 | Solute carrier family 2, facilitated glucose transporter member 10 | chr20 | GO:0030512 | Not Cancer Driver | No | 98 | 0.181 | 72 | 15 | 0.208 | 8 |
| SMAD6 | SMAD6 | O43541 | Mothers against decapentaplegic homolog 6 | chr15 | GO:0030512 | Not Cancer Driver | No | 38 | 0.077 | 248 | 7 | 0.028 | 7 |
| SMAD7 | SMAD7 | O15105 | Mothers against decapentaplegic homolog 7 | chr18 | GO:0030512 | Not Cancer Driver | No | 40 | 0.094 | 139 | 0 | 0.0 | 0 |
| SMURF1 | SMURF1 | Q9HCE7 | E3 ubiquitin-protein ligase SMURF1 | chr7 | GO:0030512 | Not Cancer Driver | No | 89 | 0.118 | 256 | 31 | 0.121 | 0 |
| SMURF2 | SMURF2 | Q9HAU4 | E3 ubiquitin-protein ligase SMURF2 | chr17 | GO:0030512 | Not Cancer Driver | No | 87 | 0.116 | 242 | 28 | 0.116 | 0 |
| SNX25 | SNX25 | Q9H3E2 | Sorting nexin-25 | chr4 | GO:0030512 | Not Cancer Driver | No | 101 | 0.12 | 114 | 10 | 0.088 | 0 |
| SNX6 | SNX6 | Q9UNH7 | Sorting nexin-6 | chr14 | GO:0030512 | Not Cancer Driver | No | 33 | 0.081 | 85 | 7 | 0.082 | 0 |
| SPINT3 | SPINT3 | P49223 | Kunitz-type protease inhibitor 3 | chr20 | GO:0030512 | Not Cancer Driver | No | 7 | 0.079 | 0 | 0 | 0.0 | 0 |
| SPRED1 | SPRED1 | Q7Z699 | Sprouty-related, EVH1 domain-containing protein 1 | chr15 | GO:0030512 | Not Cancer Driver | No | 71 | 0.16 | 194 | 35 | 0.18 | 2 |
| SPRED2 | SPRED2 | Q7Z698 | Sprouty-related, EVH1 domain-containing protein 2 | chr2 | GO:0030512 | Not Cancer Driver | No | 73 | 0.175 | 228 | 43 | 0.189 | 0 |
| SPRED3_ENST00000586301 | SPRED3 | Q2MJR0 | Sprouty-related, EVH1 domain-containing protein 3 | chr19 | GO:0030512 | Not Cancer Driver | No | 31 | 0.076 | 207 | 15 | 0.072 | 0 |
| SPRY1 | SPRY1 | O43609 | Protein sprouty homolog 1 | chr4 | GO:0030512 | Not Cancer Driver | No | 46 | 0.144 | 168 | 26 | 0.155 | 0 |
| SPRY2 | SPRY2 | O43597 | Protein sprouty homolog 2 | chr13 | GO:0030512 | Not Cancer Driver | No | 46 | 0.146 | 169 | 29 | 0.172 | 1 |
| STRAP | STRAP | Q9Y3F4 | Serine-threonine kinase receptor-associated protein | chr12 | GO:0030512 | Not Cancer Driver | No | 44 | 0.126 | 40 | 5 | 0.125 | 0 |
| STUB1 | STUB1 | Q9UNE7 | E3 ubiquitin-protein ligase CHIP | chr16 | GO:0030512 | Not Cancer Driver | No | 35 | 0.116 | 112 | 14 | 0.125 | 12 |
| TGFB1I1 | TGFB1I1 | O43294 | Transforming growth factor beta-1-induced transcript 1 protein | chr16 | GO:0030512 | Not Cancer Driver | No | 61 | 0.132 | 219 | 34 | 0.155 | 0 |
| TGFB3 | TGFB3 | P10600 | Transforming growth factor beta-3 proprotein | chr14 | GO:0030512 | Not Cancer Driver | No | 45 | 0.109 | 96 | 14 | 0.146 | 1 |
| TGFBR3_ENST00000525962 | TGFBR3 | Q03167 | Transforming growth factor beta receptor type 3 | chr1 | GO:0030512 | Not Cancer Driver | No | 129 | 0.152 | 268 | 41 | 0.153 | 0 |
| TP53_ENST00000445888 | TP53 | P04637 | Cellular tumor antigen p53 | chr17 | GO:0030512 | Census, Compendium | Yes | 2891 | 7.356 | 282 | 1466 | 5.199 | 83 |
| VASN | VASN | Q6EMK4 | Vasorin | chr16 | GO:0030512 | Not Cancer Driver | No | 37 | 0.055 | 233 | 8 | 0.034 | 0 |
| VEPH1 | VEPH1 | Q14D04 | Ventricular zone-expressed PH domain-containing protein homolog 1 | chr3 | GO:0030512 | Not Cancer Driver | No | 136 | 0.163 | 186 | 34 | 0.183 | 0 |
| WFIKKN1 | WFIKKN1 | Q96NZ8 | WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 1 | chr16 | GO:0030512 | Not Cancer Driver | No | 38 | 0.069 | 90 | 4 | 0.044 | 0 |
| WFIKKN2 | WFIKKN2 | Q8TEU8 | WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 | chr17 | GO:0030512 | Not Cancer Driver | No | 114 | 0.198 | 94 | 32 | 0.34 | 0 |
| WNT1 | WNT1 | P04628 | Proto-oncogene Wnt-1 | chr12 | GO:0030512 | Not Cancer Driver | No | 29 | 0.078 | 25 | 0 | 0.0 | 8 |
| ZBTB7A_ENST00000601588 | ZBTB7A | O95365 | Zinc finger and BTB domain-containing protein 7A | chr19 | GO:0030512 | Not Cancer Driver | No | 60 | 0.103 | 285 | 30 | 0.105 | 0 |
| ZNF451 | ZNF451 | Q9Y4E5 | E3 SUMO-protein ligase ZNF451 | chr6 | GO:0030512 | Not Cancer Driver | No | 169 | 0.159 | 191 | 25 | 0.131 | 0 |