Total number of protein in "GO:0030510" GO term: 54
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACVRL1 | ACVRL1 | P37023 | Serine/threonine-protein kinase receptor R3 | chr12 | GO:0030510 | Not Cancer Driver | No | 93 | 0.185 | 60 | 11 | 0.183 | 82 |
| BMP4 | BMP4 | P12644 | Bone morphogenetic protein 4 | chr14 | GO:0030510 | Not Cancer Driver | No | 86 | 0.211 | 142 | 26 | 0.183 | 5 |
| BMPR2 | BMPR2 | Q13873 | Bone morphogenetic protein receptor type-2 | chr2 | GO:0030510 | Compendium | Yes | 141 | 0.136 | 601 | 70 | 0.116 | 19 |
| CCN1 | CCN1 | O00622 | CCN family member 1 | chr1 | GO:0030510 | Not Cancer Driver | No | 33 | 0.087 | 12 | 0 | 0.0 | 0 |
| CDH5 | CDH5 | P33151 | Cadherin-5 | chr16 | GO:0030510 | Not Cancer Driver | No | 144 | 0.184 | 305 | 55 | 0.18 | 0 |
| CER1 | CER1 | O95813 | Cerberus | chr9 | GO:0030510 | Not Cancer Driver | No | 70 | 0.262 | 119 | 27 | 0.227 | 0 |
| CRB2 | CRB2 | Q5IJ48 | Protein crumbs homolog 2 | chr9 | GO:0030510 | Not Cancer Driver | No | 155 | 0.121 | 72 | 0 | 0.0 | 5 |
| DAND5 | DAND5 | Q8N907 | DAN domain family member 5 | chr19 | GO:0030510 | Not Cancer Driver | No | 32 | 0.169 | 26 | 3 | 0.115 | 0 |
| ENG | ENG | P17813 | Endoglin | chr9 | GO:0030510 | Not Cancer Driver | No | 60 | 0.091 | 114 | 15 | 0.132 | 32 |
| FBN1 | FBN1 | P35555 | Fibrillin-1 | chr15 | GO:0030510 | Not Cancer Driver | No | 466 | 0.162 | 110 | 16 | 0.145 | 360 |
| FBXL15 | FBXL15 | Q9H469 | F-box/LRR-repeat protein 15 | chr10 | GO:0030510 | Not Cancer Driver | No | 9 | 0.03 | 16 | 1 | 0.062 | 0 |
| FKBP8_ENST00000222308 | FKBP8 | Q14318 | Peptidyl-prolyl cis-trans isomerase FKBP8 | chr19 | GO:0030510 | Not Cancer Driver | No | 71 | 0.172 | 160 | 25 | 0.156 | 0 |
| FOXD1 | FOXD1 | Q16676 | Forkhead box protein D1 | chr5 | GO:0030510 | Not Cancer Driver | No | 10 | 0.022 | 259 | 5 | 0.019 | 0 |
| FST | FST | P19883 | Follistatin | chr5 | GO:0030510 | Not Cancer Driver | No | 50 | 0.145 | 20 | 7 | 0.35 | 0 |
| FSTL1 | FSTL1 | Q12841 | Follistatin-related protein 1 | chr3 | GO:0030510 | Not Cancer Driver | No | 41 | 0.133 | 51 | 7 | 0.137 | 0 |
| FSTL3 | FSTL3 | O95633 | Follistatin-related protein 3 | chr19 | GO:0030510 | Census | Yes | 17 | 0.065 | 28 | 2 | 0.071 | 0 |
| GATA4_ENST00000335135 | GATA4 | P43694 | Transcription factor GATA-4 | chr8 | GO:0030510 | Not Cancer Driver | No | 48 | 0.109 | 301 | 34 | 0.113 | 18 |
| GATA6 | GATA6 | Q92908 | Transcription factor GATA-6 | chr18 | GO:0030510 | Not Cancer Driver | No | 57 | 0.096 | 476 | 51 | 0.107 | 10 |
| GDF5_ENST00000374369 | GDF5 | P43026 | Growth/differentiation factor 5 | chr20 | GO:0030510 | Not Cancer Driver | No | 104 | 0.208 | 255 | 50 | 0.196 | 24 |
| GPC3_ENST00000370818 | GPC3 | P51654 | Glypican-3 | chrX | GO:0030510 | Census | Yes | 89 | 0.153 | 86 | 11 | 0.128 | 1 |
| GREM1 | GREM1 | O60565 | Gremlin-1 | chr15 | GO:0030510 | Not Cancer Driver | No | 25 | 0.136 | 77 | 12 | 0.156 | 0 |
| GREM2 | GREM2 | Q9H772 | Gremlin-2 | chr1 | GO:0030510 | Not Cancer Driver | No | 54 | 0.321 | 22 | 9 | 0.409 | 3 |
| HES1 | HES1 | Q14469 | Transcription factor HES-1 | chr3 | GO:0030510 | Not Cancer Driver | No | 37 | 0.132 | 226 | 32 | 0.142 | 0 |
| HES5 | HES5 | Q5TA89 | Transcription factor HES-5 | chr1 | GO:0030510 | Not Cancer Driver | No | 1 | 0.006 | 73 | 0 | 0.0 | 0 |
| HOXA13 | HOXA13 | P31271 | Homeobox protein Hox-A13 | chr7 | GO:0030510 | Census | Yes | 37 | 0.095 | 171 | 22 | 0.129 | 4 |
| ILK_ENST00000299421 | ILK | Q13418 | Integrin-linked protein kinase | chr11 | GO:0030510 | Not Cancer Driver | No | 45 | 0.1 | 71 | 9 | 0.127 | 0 |
| ITGA3 | ITGA3 | P26006 | Integrin alpha-3 | chr17 | GO:0030510 | Not Cancer Driver | No | 106 | 0.101 | 129 | 18 | 0.14 | 3 |
| KDR | KDR | P35968 | Vascular endothelial growth factor receptor 2 | chr4 | GO:0030510 | Census, Compendium | Yes | 357 | 0.263 | 275 | 55 | 0.2 | 2 |
| KIAA1324L | ELAPOR2 | A8MWY0 | Endosome/lysosome-associated apoptosis and autophagy regulator family member 2 | chr7 | GO:0030510 | Not Cancer Driver | No | 170 | 0.165 | 74 | 6 | 0.081 | 0 |
| MSX1 | MSX1 | P28360 | Homeobox protein MSX-1 | chr4 | GO:0030510 | Not Cancer Driver | No | 39 | 0.129 | 197 | 16 | 0.081 | 7 |
| MSX2 | MSX2 | P35548 | Homeobox protein MSX-2 | chr5 | GO:0030510 | Not Cancer Driver | No | 27 | 0.101 | 168 | 14 | 0.083 | 4 |
| NBL1_ENST00000602662 | NBL1 | P41271 | Neuroblastoma suppressor of tumorigenicity 1 | chr1 | GO:0030510 | Not Cancer Driver | No | 18 | 0.099 | 64 | 4 | 0.062 | 0 |
| NEO1_ENST00000261908 | NEO1 | Q92859 | Neogenin | chr15 | GO:0030510 | Not Cancer Driver | No | 182 | 0.125 | 706 | 96 | 0.136 | 0 |
| NOTCH1 | NOTCH1 | P46531 | Neurogenic locus notch homolog protein 1 | chr9 | GO:0030510 | Census, Compendium | Yes | 363 | 0.142 | 686 | 87 | 0.127 | 3 |
| NOTCH2 | NOTCH2 | Q04721 | Neurogenic locus notch homolog protein 2 | chr1 | GO:0030510 | Census, Compendium | Yes | 282 | 0.114 | 630 | 77 | 0.122 | 1 |
| NUMA1 | NUMA1 | Q14980 | Nuclear mitotic apparatus protein 1 | chr11 | GO:0030510 | Census, Compendium | Yes | 234 | 0.111 | 1864 | 203 | 0.109 | 0 |
| PCSK6 | PCSK6 | P29122 | Proprotein convertase subtilisin/kexin type 6 | chr15 | GO:0030510 | Not Cancer Driver | No | 138 | 0.142 | 207 | 45 | 0.217 | 0 |
| PELO | PELO | Q9BRX2 | Protein pelota homolog | chr5 | GO:0030510 | Not Cancer Driver | No | 38 | 0.099 | 67 | 10 | 0.149 | 0 |
| RBPJ_ENST00000361572 | RBPJ | Q06330 | Recombining binding protein suppressor of hairless | chr4 | GO:0030510 | Not Cancer Driver | No | 49 | 0.098 | 151 | 19 | 0.126 | 2 |
| RGMA_ENST00000329082 | RGMA | Q96B86 | Repulsive guidance molecule A | chr15 | GO:0030510 | Not Cancer Driver | No | 63 | 0.14 | 105 | 13 | 0.124 | 0 |
| RNF165 | RNF165 | Q6ZSG1 | E3 ubiquitin-protein ligase RNF165 | chr18 | GO:0030510 | Not Cancer Driver | No | 62 | 0.179 | 225 | 40 | 0.178 | 0 |
| SCUBE3 | SCUBE3 | Q8IX30 | Signal peptide, CUB and EGF-like domain-containing protein 3 | chr6 | GO:0030510 | Not Cancer Driver | No | 131 | 0.132 | 110 | 17 | 0.155 | 2 |
| SFRP4 | SFRP4 | Q6FHJ7 | Secreted frizzled-related protein 4 | chr7 | GO:0030510 | Census | Yes | 81 | 0.234 | 68 | 22 | 0.324 | 0 |
| SFRP5 | SFRP5 | Q5T4F7 | Secreted frizzled-related protein 5 | chr10 | GO:0030510 | Not Cancer Driver | No | 26 | 0.082 | 7 | 3 | 0.429 | 0 |
| SMAD2_ENST00000402690 | SMAD2 | Q15796 | Mothers against decapentaplegic homolog 2 | chr18 | GO:0030510 | Census, Compendium | Yes | 79 | 0.169 | 137 | 12 | 0.088 | 0 |
| SMAD4_ENST00000398417 | SMAD4 | Q13485 | Mothers against decapentaplegic homolog 4 | chr18 | GO:0030510 | Census, Compendium | Yes | 198 | 0.359 | 195 | 17 | 0.087 | 8 |
| SOX11 | SOX11 | P35716 | Transcription factor SOX-11 | chr2 | GO:0030510 | Not Cancer Driver | No | 61 | 0.138 | 368 | 53 | 0.144 | 2 |
| SULF1_ENST00000458141 | SULF1 | Q8IWU6 | Extracellular sulfatase Sulf-1 | chr8 | GO:0030510 | Not Cancer Driver | No | 246 | 0.282 | 269 | 71 | 0.264 | 0 |
| TBX20 | TBX20 | Q9UMR3 | T-box transcription factor TBX20 | chr7 | GO:0030510 | Not Cancer Driver | No | 117 | 0.262 | 201 | 54 | 0.269 | 2 |
| TFAP2B | TFAP2B | Q92481 | Transcription factor AP-2-beta | chr6 | GO:0030510 | Not Cancer Driver | No | 114 | 0.248 | 306 | 75 | 0.245 | 6 |
| TWSG1 | TWSG1 | Q9GZX9 | Twisted gastrulation protein homolog 1 | chr18 | GO:0030510 | Not Cancer Driver | No | 27 | 0.121 | 19 | 3 | 0.158 | 0 |
| UBE2O | UBE2O | Q9C0C9 | (E3-independent) E2 ubiquitin-conjugating enzyme | chr17 | GO:0030510 | Not Cancer Driver | No | 129 | 0.1 | 716 | 68 | 0.095 | 0 |
| XIAP_ENST00000434753 | XIAP | P98170 | E3 ubiquitin-protein ligase XIAP | chrX | GO:0030510 | Not Cancer Driver | No | 89 | 0.179 | 55 | 6 | 0.109 | 0 |
| ZNF423 | ZNF423 | Q2M1K9 | Zinc finger protein 423 | chr16 | GO:0030510 | Not Cancer Driver | No | 340 | 0.265 | 416 | 108 | 0.26 | 2 |