Total number of protein in "GO:0030509" GO term: 76
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACVR1_ENST00000434821 | ACVR1 | Q04771 | Activin receptor type-1 | chr2 | GO:0030509 | Census, Compendium | Yes | 78 | 0.153 | 21 | 8 | 0.381 | 8 |
| ACVR2A_ENST00000404590 | ACVR2A | P27037 | Activin receptor type-2A | chr2 | GO:0030509 | Census, Compendium | Yes | 98 | 0.191 | 56 | 6 | 0.107 | 0 |
| ACVR2B | ACVR2B | Q13705 | Activin receptor type-2B | chr3 | GO:0030509 | Not Cancer Driver | No | 83 | 0.162 | 70 | 14 | 0.2 | 2 |
| ACVRL1 | ACVRL1 | P37023 | Serine/threonine-protein kinase receptor R3 | chr12 | GO:0030509 | Not Cancer Driver | No | 93 | 0.185 | 60 | 11 | 0.183 | 82 |
| ATF2 | ATF2 | P15336 | Cyclic AMP-dependent transcription factor ATF-2 | chr2 | GO:0030509 | Not Cancer Driver | No | 65 | 0.129 | 451 | 58 | 0.129 | 0 |
| BMP10 | BMP10 | O95393 | Bone morphogenetic protein 10 | chr2 | GO:0030509 | Not Cancer Driver | No | 88 | 0.208 | 87 | 13 | 0.149 | 0 |
| BMP15 | BMP15 | O95972 | Bone morphogenetic protein 15 | chrX | GO:0030509 | Not Cancer Driver | No | 91 | 0.232 | 81 | 15 | 0.185 | 13 |
| BMP2 | BMP2 | P12643 | Bone morphogenetic protein 2 | chr20 | GO:0030509 | Not Cancer Driver | No | 73 | 0.184 | 139 | 26 | 0.187 | 0 |
| BMP4 | BMP4 | P12644 | Bone morphogenetic protein 4 | chr14 | GO:0030509 | Not Cancer Driver | No | 86 | 0.211 | 142 | 26 | 0.183 | 5 |
| BMP5 | BMP5 | P22003 | Bone morphogenetic protein 5 | chr6 | GO:0030509 | Census | Yes | 163 | 0.359 | 112 | 62 | 0.554 | 0 |
| BMP6 | BMP6 | P22004 | Bone morphogenetic protein 6 | chr6 | GO:0030509 | Not Cancer Driver | No | 95 | 0.185 | 226 | 51 | 0.226 | 0 |
| BMP7 | BMP7 | P18075 | Bone morphogenetic protein 7 | chr20 | GO:0030509 | Not Cancer Driver | No | 91 | 0.211 | 69 | 18 | 0.261 | 0 |
| BMP8A | BMP8A | Q7Z5Y6 | Bone morphogenetic protein 8A | chr1 | GO:0030509 | Not Cancer Driver | No | 26 | 0.065 | 93 | 2 | 0.022 | 0 |
| BMP8B | BMP8B | P34820 | Bone morphogenetic protein 8B | chr1 | GO:0030509 | Not Cancer Driver | No | 21 | 0.052 | 90 | 3 | 0.033 | 0 |
| BMPR1A | BMPR1A | P36894 | Bone morphogenetic protein receptor type-1A | chr10 | GO:0030509 | Census, Compendium | Yes | 66 | 0.124 | 21 | 0 | 0.0 | 8 |
| BMPR1B_ENST00000394931 | BMPR1B | O00238 | Bone morphogenetic protein receptor type-1B | chr4 | GO:0030509 | Not Cancer Driver | No | 84 | 0.167 | 64 | 12 | 0.188 | 5 |
| BMPR2 | BMPR2 | Q13873 | Bone morphogenetic protein receptor type-2 | chr2 | GO:0030509 | Compendium | Yes | 141 | 0.136 | 601 | 70 | 0.116 | 19 |
| CHRD | CHRD | Q9H2X0 | Chordin | chr3 | GO:0030509 | Not Cancer Driver | No | 171 | 0.179 | 308 | 61 | 0.198 | 0 |
| COMP | COMP | P49747 | Cartilage oligomeric matrix protein | chr19 | GO:0030509 | Not Cancer Driver | No | 97 | 0.128 | 306 | 52 | 0.17 | 61 |
| DDX5 | DDX5 | P17844 | Probable ATP-dependent RNA helicase DDX5 | chr17 | GO:0030509 | Census | Yes | 74 | 0.121 | 225 | 23 | 0.102 | 0 |
| DLX5 | DLX5 | P56178 | Homeobox protein DLX-5 | chr7 | GO:0030509 | Not Cancer Driver | No | 71 | 0.246 | 223 | 57 | 0.256 | 1 |
| DSG4_ENST00000308128 | DSG4 | Q86SJ6 | Desmoglein-4 | chr18 | GO:0030509 | Not Cancer Driver | No | 275 | 0.264 | 186 | 44 | 0.237 | 0 |
| EGR1 | EGR1 | P18146 | Early growth response protein 1 | chr5 | GO:0030509 | Not Cancer Driver | No | 78 | 0.144 | 501 | 72 | 0.144 | 0 |
| ENG | ENG | P17813 | Endoglin | chr9 | GO:0030509 | Not Cancer Driver | No | 60 | 0.091 | 114 | 15 | 0.132 | 32 |
| ETV2_ENST00000403402 | ETV2 | O00321 | ETS translocation variant 2 | chr19 | GO:0030509 | Not Cancer Driver | No | 23 | 0.067 | 227 | 15 | 0.066 | 0 |
| EXT1 | EXT1 | Q16394 | Exostosin-1 | chr8 | GO:0030509 | Census | Yes | 107 | 0.143 | 58 | 7 | 0.121 | 12 |
| FAM83G_ENST00000345041 | FAM83G | A6ND36 | Protein FAM83G | chr17 | GO:0030509 | Not Cancer Driver | No | 108 | 0.131 | 531 | 65 | 0.122 | 0 |
| FST | FST | P19883 | Follistatin | chr5 | GO:0030509 | Not Cancer Driver | No | 50 | 0.145 | 20 | 7 | 0.35 | 0 |
| GDF1 | GDF1 | P27539 | Embryonic growth/differentiation factor 1 | chr19 | GO:0030509 | Not Cancer Driver | No | 8 | 0.022 | 144 | 5 | 0.035 | 6 |
| GDF15 | GDF15 | Q99988 | Growth/differentiation factor 15 | chr19 | GO:0030509 | Not Cancer Driver | No | 39 | 0.127 | 143 | 20 | 0.14 | 0 |
| GDF3 | GDF3 | Q9NR23 | Growth/differentiation factor 3 | chr12 | GO:0030509 | Not Cancer Driver | No | 79 | 0.217 | 3 | 3 | 1.0 | 5 |
| GDF5_ENST00000374369 | GDF5 | P43026 | Growth/differentiation factor 5 | chr20 | GO:0030509 | Not Cancer Driver | No | 104 | 0.208 | 255 | 50 | 0.196 | 24 |
| GDF6 | GDF6 | Q6KF10 | Growth/differentiation factor 6 | chr8 | GO:0030509 | Not Cancer Driver | No | 91 | 0.2 | 225 | 46 | 0.204 | 14 |
| GDF7 | GDF7 | Q7Z4P5 | Growth/differentiation factor 7 | chr2 | GO:0030509 | Not Cancer Driver | No | 33 | 0.073 | 213 | 8 | 0.038 | 0 |
| GDF9 | GDF9 | O60383 | Growth/differentiation factor 9 | chr5 | GO:0030509 | Not Cancer Driver | No | 72 | 0.159 | 53 | 15 | 0.283 | 0 |
| HFE | HFE | Q30201 | Hereditary hemochromatosis protein | chr6 | GO:0030509 | Not Cancer Driver | No | 55 | 0.158 | 27 | 2 | 0.074 | 11 |
| HIVEP1 | HIVEP1 | P15822 | Zinc finger protein 40 | chr6 | GO:0030509 | Not Cancer Driver | No | 344 | 0.127 | 2238 | 292 | 0.13 | 0 |
| HJV | HJV | Q6ZVN8 | Hemojuvelin | chr1 | GO:0030509 | Not Cancer Driver | No | 75 | 0.176 | 117 | 27 | 0.231 | 14 |
| LEF1 | LEF1 | Q9UJU2 | Lymphoid enhancer-binding factor 1 | chr4 | GO:0030509 | Census | Yes | 64 | 0.16 | 370 | 57 | 0.154 | 0 |
| LEFTY1 | LEFTY1 | O75610 | Left-right determination factor 1 | chr1 | GO:0030509 | Not Cancer Driver | No | 55 | 0.15 | 65 | 8 | 0.123 | 0 |
| LEFTY2 | LEFTY2 | O00292 | Left-right determination factor 2 | chr1 | GO:0030509 | Not Cancer Driver | No | 38 | 0.104 | 54 | 4 | 0.074 | 1 |
| MAPK3 | MAPK3 | P27361 | Mitogen-activated protein kinase 3 | chr16 | GO:0030509 | Not Cancer Driver | No | 38 | 0.1 | 49 | 5 | 0.102 | 0 |
| MEGF8 | MEGF8 | Q7Z7M0 | Multiple epidermal growth factor-like domains protein 8 | chr19 | GO:0030509 | Not Cancer Driver | No | 363 | 0.128 | 476 | 59 | 0.124 | 3 |
| MSX1 | MSX1 | P28360 | Homeobox protein MSX-1 | chr4 | GO:0030509 | Not Cancer Driver | No | 39 | 0.129 | 197 | 16 | 0.081 | 7 |
| MSX2 | MSX2 | P35548 | Homeobox protein MSX-2 | chr5 | GO:0030509 | Not Cancer Driver | No | 27 | 0.101 | 168 | 14 | 0.083 | 4 |
| NODAL | NODAL | Q96S42 | Nodal homolog | chr10 | GO:0030509 | Not Cancer Driver | No | 40 | 0.115 | 34 | 8 | 0.235 | 4 |
| NOG | NOG | Q13253 | Noggin | chr17 | GO:0030509 | Not Cancer Driver | No | 22 | 0.095 | 86 | 9 | 0.105 | 20 |
| PDCD4 | PDCD4 | Q53EL6 | Programmed cell death protein 4 | chr10 | GO:0030509 | Not Cancer Driver | No | 57 | 0.122 | 187 | 32 | 0.171 | 0 |
| PPARG | PPARG | P37231 | Peroxisome proliferator-activated receptor gamma | chr3 | GO:0030509 | Census | Yes | 72 | 0.143 | 44 | 4 | 0.091 | 3 |
| RGMA_ENST00000329082 | RGMA | Q96B86 | Repulsive guidance molecule A | chr15 | GO:0030509 | Not Cancer Driver | No | 63 | 0.14 | 105 | 13 | 0.124 | 0 |
| RGMB_ENST00000513185 | RGMB | Q6NW40 | Repulsive guidance molecule B | chr5 | GO:0030509 | Not Cancer Driver | No | 42 | 0.096 | 84 | 12 | 0.143 | 0 |
| ROR2 | ROR2 | Q01974 | Tyrosine-protein kinase transmembrane receptor ROR2 | chr9 | GO:0030509 | Not Cancer Driver | No | 203 | 0.215 | 299 | 71 | 0.237 | 5 |
| RUNX2_ENST00000647337 | RUNX2 | Q13950 | Runt-related transcription factor 2 | chr6 | GO:0030509 | Not Cancer Driver | No | 83 | 0.159 | 447 | 73 | 0.163 | 47 |
| SLC33A1_ENST00000643144 | SLC33A1 | O00400 | Acetyl-coenzyme A transporter 1 | chr3 | GO:0030509 | Not Cancer Driver | No | 64 | 0.117 | 54 | 8 | 0.148 | 2 |
| SLC39A5 | SLC39A5 | Q6ZMH5 | Zinc transporter ZIP5 | chr12 | GO:0030509 | Not Cancer Driver | No | 67 | 0.124 | 139 | 18 | 0.129 | 1 |
| SMAD1 | SMAD1 | Q15797 | Mothers against decapentaplegic homolog 1 | chr4 | GO:0030509 | Not Cancer Driver | No | 54 | 0.116 | 161 | 22 | 0.137 | 0 |
| SMAD2_ENST00000402690 | SMAD2 | Q15796 | Mothers against decapentaplegic homolog 2 | chr18 | GO:0030509 | Census, Compendium | Yes | 79 | 0.169 | 137 | 12 | 0.088 | 0 |
| SMAD3 | SMAD3 | P84022 | Mothers against decapentaplegic homolog 3 | chr15 | GO:0030509 | Census, Compendium | Yes | 97 | 0.228 | 111 | 19 | 0.171 | 5 |
| SMAD4_ENST00000398417 | SMAD4 | Q13485 | Mothers against decapentaplegic homolog 4 | chr18 | GO:0030509 | Census, Compendium | Yes | 198 | 0.359 | 195 | 17 | 0.087 | 8 |
| SMAD5_ENST00000509297 | SMAD5 | Q99717 | Mothers against decapentaplegic homolog 5 | chr5 | GO:0030509 | Not Cancer Driver | No | 44 | 0.095 | 172 | 11 | 0.064 | 0 |
| SMAD6 | SMAD6 | O43541 | Mothers against decapentaplegic homolog 6 | chr15 | GO:0030509 | Not Cancer Driver | No | 38 | 0.077 | 248 | 7 | 0.028 | 7 |
| SMAD7 | SMAD7 | O15105 | Mothers against decapentaplegic homolog 7 | chr18 | GO:0030509 | Not Cancer Driver | No | 40 | 0.094 | 139 | 0 | 0.0 | 0 |
| SMAD9 | SMAD9 | O15198 | Mothers against decapentaplegic homolog 9 | chr13 | GO:0030509 | Not Cancer Driver | No | 79 | 0.169 | 132 | 14 | 0.106 | 1 |
| SMPD3 | SMPD3 | Q9NY59 | Sphingomyelin phosphodiesterase 3 | chr16 | GO:0030509 | Not Cancer Driver | No | 92 | 0.14 | 224 | 29 | 0.129 | 0 |
| SMURF1 | SMURF1 | Q9HCE7 | E3 ubiquitin-protein ligase SMURF1 | chr7 | GO:0030509 | Not Cancer Driver | No | 89 | 0.118 | 256 | 31 | 0.121 | 0 |
| SOSTDC1 | SOSTDC1 | Q6X4U4 | Sclerostin domain-containing protein 1 | chr7 | GO:0030509 | Not Cancer Driver | No | 22 | 0.107 | 72 | 3 | 0.042 | 0 |
| TGFB1 | TGFB1 | P01137 | Transforming growth factor beta-1 proprotein | chr19 | GO:0030509 | Not Cancer Driver | No | 41 | 0.105 | 41 | 4 | 0.098 | 10 |
| TGFB2_ENST00000366930 | TGFB2 | P61812 | Transforming growth factor beta-2 proprotein | chr1 | GO:0030509 | Not Cancer Driver | No | 63 | 0.152 | 47 | 8 | 0.17 | 3 |
| TGFB3 | TGFB3 | P10600 | Transforming growth factor beta-3 proprotein | chr14 | GO:0030509 | Not Cancer Driver | No | 45 | 0.109 | 96 | 14 | 0.146 | 1 |
| TGFBR3_ENST00000525962 | TGFBR3 | Q03167 | Transforming growth factor beta receptor type 3 | chr1 | GO:0030509 | Not Cancer Driver | No | 129 | 0.152 | 268 | 41 | 0.153 | 0 |
| TMEM100 | TMEM100 | Q9NV29 | Transmembrane protein 100 | chr17 | GO:0030509 | Not Cancer Driver | No | 29 | 0.216 | 0 | 0 | 0.0 | 0 |
| TWSG1 | TWSG1 | Q9GZX9 | Twisted gastrulation protein homolog 1 | chr18 | GO:0030509 | Not Cancer Driver | No | 27 | 0.121 | 19 | 3 | 0.158 | 0 |
| USP15 | USP15 | Q9Y4E8 | Ubiquitin carboxyl-terminal hydrolase 15 | chr12 | GO:0030509 | Not Cancer Driver | No | 136 | 0.139 | 259 | 39 | 0.151 | 0 |
| USP9X_ENST00000378308 | USP9X | Q93008 | Probable ubiquitin carboxyl-terminal hydrolase FAF-X | chrX | GO:0030509 | Census, Compendium | Yes | 339 | 0.133 | 405 | 51 | 0.126 | 1 |
| USP9Y | USP9Y | O00507 | Probable ubiquitin carboxyl-terminal hydrolase FAF-Y | chrY | GO:0030509 | Not Cancer Driver | No | 83 | 0.032 | 349 | 6 | 0.017 | 0 |
| ZNF8 | ZNF8 | P17098 | Zinc finger protein 8 | chr19 | GO:0030509 | Not Cancer Driver | No | 82 | 0.143 | 407 | 57 | 0.14 | 0 |