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Total number of protein in "GO:0030336" GO term:  263

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABCC8_ENST00000389817 ABCC8 Q09428 ATP-binding cassette sub-family C member 8 chr11 GO:0030336 Not Cancer Driver No 255 0.161 138 23 0.167 97
ABHD2_ENST00000565973 ABHD2 P08910 Monoacylglycerol lipase ABHD2 chr15 GO:0030336 Not Cancer Driver No 54 0.127 8 1 0.125 0
ABHD6 ABHD6 Q9BV23 Monoacylglycerol lipase ABHD6 chr3 GO:0030336 Not Cancer Driver No 38 0.113 11 2 0.182 0
ACVR1C ACVR1C Q8NER5 Activin receptor type-1C chr2 GO:0030336 Not Cancer Driver No 90 0.183 3 1 0.333 0
ACVRL1 ACVRL1 P37023 Serine/threonine-protein kinase receptor R3 chr12 GO:0030336 Not Cancer Driver No 93 0.185 60 11 0.183 82
ADA ADA P00813 Adenosine deaminase chr20 GO:0030336 Not Cancer Driver No 50 0.138 44 9 0.205 27
ADAM15 ADAM15 Q13444 Disintegrin and metalloproteinase domain-containing protein 15 chr1 GO:0030336 Not Cancer Driver No 104 0.121 213 29 0.136 0
ADAMTS9 ADAMTS9 Q9P2N4 A disintegrin and metalloproteinase with thrombospondin motifs 9 chr3 GO:0030336 Not Cancer Driver No 288 0.149 235 38 0.162 0
ADARB1 ADARB1 P78563 Double-stranded RNA-specific editase 1 chr21 GO:0030336 Not Cancer Driver No 102 0.138 348 34 0.098 1
ADGRB1_ENST00000323289 ADGRB1 O14514 Adhesion G protein-coupled receptor B1 chr8 GO:0030336 Compendium Yes 213 0.134 485 47 0.097 0
ADGRG1 ADGRG1 Q9Y653 Adhesion G-protein coupled receptor G1 chr16 GO:0030336 Not Cancer Driver No 64 0.092 67 4 0.06 9
ADIPOQ ADIPOQ Q15848 Adiponectin chr3 GO:0030336 Not Cancer Driver No 39 0.16 92 21 0.228 1
ADIPOR1 ADIPOR1 Q96A54 Adiponectin receptor protein 1 chr1 GO:0030336 Not Cancer Driver No 63 0.168 69 10 0.145 0
ADORA1 ADORA1 P30542 Adenosine receptor A1 chr1 GO:0030336 Not Cancer Driver No 64 0.196 12 4 0.333 0
ADORA3 ADORA3 P0DMS8 Adenosine receptor A3 chr1 GO:0030336 Not Cancer Driver No 45 0.142 4 1 0.25 0
ADTRP_ENST00000414691 ADTRP Q96IZ2 Androgen-dependent TFPI-regulating protein chr6 GO:0030336 Not Cancer Driver No 41 0.178 2 0 0.0 0
AFDN_ENST00000447894 AFDN P55196 Afadin chr6 GO:0030336 Census Yes 248 0.136 1247 180 0.144 0
AGTR2 AGTR2 P50052 Type-2 angiotensin II receptor chrX GO:0030336 Not Cancer Driver No 98 0.27 0 0 0.0 0
AIF1 AIF1 P55008 Allograft inflammatory factor 1 chr6 GO:0030336 Not Cancer Driver No 14 0.095 61 6 0.098 0
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:0030336 Census, Compendium Yes 108 0.225 158 24 0.152 4
ALOX15B ALOX15B O15296 Polyunsaturated fatty acid lipoxygenase ALOX15B chr17 GO:0030336 Not Cancer Driver No 99 0.146 62 12 0.194 0
ANGPT2 ANGPT2 O15123 Angiopoietin-2 chr8 GO:0030336 Not Cancer Driver No 63 0.127 96 10 0.104 1
ANGPT4 ANGPT4 Q9Y264 Angiopoietin-4 chr20 GO:0030336 Not Cancer Driver No 104 0.207 150 32 0.213 0
APEX1_ENST00000555414 APEX1 P27695 DNA-(apurinic or apyrimidinic site) endonuclease chr14 GO:0030336 Not Cancer Driver No 34 0.107 103 14 0.136 0
APOD APOD P05090 Apolipoprotein D chr3 GO:0030336 Not Cancer Driver No 34 0.18 13 2 0.154 0
APOE APOE P02649 Apolipoprotein E chr19 GO:0030336 Not Cancer Driver No 25 0.079 124 6 0.048 12
APOH APOH P02749 Beta-2-glycoprotein 1 chr17 GO:0030336 Not Cancer Driver No 67 0.194 0 0 0.0 0
ARHGAP4_ENST00000350060 ARHGAP4 P98171 Rho GTPase-activating protein 4 chrX GO:0030336 Not Cancer Driver No 125 0.132 464 76 0.164 0
ARHGDIB ARHGDIB P52566 Rho GDP-dissociation inhibitor 2 chr12 GO:0030336 Not Cancer Driver No 33 0.164 92 13 0.141 0
ARID2 ARID2 Q68CP9 AT-rich interactive domain-containing protein 2 chr12 GO:0030336 Census, Compendium Yes 272 0.148 1143 141 0.123 0
ARPIN ARPIN Q7Z6K5 Arpin chr15 GO:0030336 Not Cancer Driver No 26 0.115 110 14 0.127 0
ATP1B2 ATP1B2 P14415 Sodium/potassium-transporting ATPase subunit beta-2 chr17 GO:0030336 Not Cancer Driver No 40 0.138 16 6 0.375 0
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:0030336 Census, Compendium Yes 24 0.1 72 5 0.069 0
BCR BCR P11274 Breakpoint cluster region protein chr22 GO:0030336 Census, Compendium Yes 146 0.115 603 69 0.114 0
BMP10 BMP10 O95393 Bone morphogenetic protein 10 chr2 GO:0030336 Not Cancer Driver No 88 0.208 87 13 0.149 0
BMP5 BMP5 P22003 Bone morphogenetic protein 5 chr6 GO:0030336 Census Yes 163 0.359 112 62 0.554 0
BMPR1A BMPR1A P36894 Bone morphogenetic protein receptor type-1A chr10 GO:0030336 Census, Compendium Yes 66 0.124 21 0 0.0 8
BST2 BST2 Q10589 Bone marrow stromal antigen 2 chr19 GO:0030336 Not Cancer Driver No 19 0.106 20 0 0.0 0
C16orf45 BMERB1 Q96MC5 bMERB domain-containing protein 1 chr16 GO:0030336 Not Cancer Driver No 32 0.157 102 16 0.157 0
C5 C5 P01031 Complement C5 chr9 GO:0030336 Not Cancer Driver No 192 0.115 84 9 0.107 0
C5AR2_ENST00000600626 C5AR2 Q9P296 C5a anaphylatoxin chemotactic receptor 2 chr19 GO:0030336 Not Cancer Driver No 60 0.178 11 3 0.273 0
C5orf30_ENST00000510890 MACIR Q96GV9 Macrophage immunometabolism regulator chr5 GO:0030336 Not Cancer Driver No 26 0.126 133 20 0.15 0
CALR CALR P27797 Calreticulin chr19 GO:0030336 Census Yes 45 0.108 245 31 0.127 0
CARD10_ENST00000251973 CARD10 Q9BWT7 Caspase recruitment domain-containing protein 10 chr22 GO:0030336 Not Cancer Driver No 94 0.091 474 40 0.084 0
CCL2 CCL2 P13500 C-C motif chemokine 2 chr17 GO:0030336 Not Cancer Driver No 20 0.202 15 5 0.333 0
CCL21 CCL21 O00585 C-C motif chemokine 21 chr9 GO:0030336 Not Cancer Driver No 14 0.104 59 6 0.102 0
CCL25 CCL25 O15444 C-C motif chemokine 25 chr19 GO:0030336 Not Cancer Driver No 20 0.133 26 6 0.231 0
CCL28 CCL28 Q9NRJ3 C-C motif chemokine 28 chr5 GO:0030336 Not Cancer Driver No 17 0.134 48 8 0.167 0
CCN3 CCN3 P48745 CCN family member 3 chr8 GO:0030336 Not Cancer Driver No 66 0.185 19 1 0.053 0
CD200R1_ENST00000471858 CD200R1 Q8TD46 Cell surface glycoprotein CD200 receptor 1 chr3 GO:0030336 Not Cancer Driver No 87 0.268 56 12 0.214 0
CD200_ENST00000315711 CD200 P41217 OX-2 membrane glycoprotein chr3 GO:0030336 Not Cancer Driver No 37 0.133 14 0 0.0 0
CD300A CD300A Q9UGN4 CMRF35-like molecule 8 chr17 GO:0030336 Not Cancer Driver No 53 0.177 70 10 0.143 0
CD74 CD74 P04233 HLA class II histocompatibility antigen gamma chain chr5 GO:0030336 Census Yes 31 0.105 185 20 0.108 0
CDH1 CDH1 P12830 Cadherin-1 chr16 GO:0030336 Census, Compendium Yes 150 0.17 400 82 0.205 5
CERS2_ENST00000368954 CERS2 Q96G23 Ceramide synthase 2 chr1 GO:0030336 Not Cancer Driver No 38 0.1 36 4 0.111 0
CHRD CHRD Q9H2X0 Chordin chr3 GO:0030336 Not Cancer Driver No 171 0.179 308 61 0.198 0
CITED2_ENST00000367651 CITED2 Q99967 Cbp/p300-interacting transactivator 2 chr6 GO:0030336 Not Cancer Driver No 23 0.085 230 18 0.078 0
CLASP1_ENST00000646274 CLASP1 Q7Z460 CLIP-associating protein 1 chr2 GO:0030336 Not Cancer Driver No 163 0.106 642 70 0.109 0
CLASP2 CLASP2 O75122 CLIP-associating protein 2 chr3 GO:0030336 Not Cancer Driver No 158 0.122 676 94 0.139 0
CLDN19 CLDN19 Q8N6F1 Claudin-19 chr1 GO:0030336 Not Cancer Driver No 27 0.121 20 2 0.1 3
CLDN3 CLDN3 O15551 Claudin-3 chr7 GO:0030336 Not Cancer Driver No 12 0.055 0 0 0.0 0
CLDN5_ENST00000618236 CLDN5 O00501 Claudin-5 chr22 GO:0030336 Not Cancer Driver No 15 0.069 0 0 0.0 0
CLIC4 CLIC4 Q9Y696 Chloride intracellular channel protein 4 chr1 GO:0030336 Not Cancer Driver No 24 0.095 49 4 0.082 0
CNN2_ENST00000263097 CNN2 Q99439 Calponin-2 chr19 GO:0030336 Not Cancer Driver No 35 0.113 166 23 0.139 0
COL3A1 COL3A1 P02461 Collagen alpha-1(III) chain chr2 GO:0030336 Census Yes 402 0.274 1182 337 0.285 103
CORO1B CORO1B Q9BR76 Coronin-1B chr11 GO:0030336 Not Cancer Driver No 41 0.084 138 10 0.072 0
CORO1C_ENST00000541050 CORO1C Q9ULV4 Coronin-1C chr12 GO:0030336 Not Cancer Driver No 61 0.129 84 13 0.155 0
CSNK2B_ENST00000375866 CSNK2B P67870 Casein kinase II subunit beta chr6 GO:0030336 Not Cancer Driver No 20 0.093 19 0 0.0 4
CX3CL1 CX3CL1 P78423 Fractalkine chr16 GO:0030336 Not Cancer Driver No 66 0.166 259 44 0.17 0
CX3CR1_ENST00000542107 CX3CR1 P49238 CX3C chemokine receptor 1 chr3 GO:0030336 Not Cancer Driver No 80 0.225 0 0 0.0 0
CXCL12_ENST00000374429 CXCL12 P48061 Stromal cell-derived factor 1 chr10 GO:0030336 Not Cancer Driver No 16 0.172 0 0 0.0 0
CXCL13 CXCL13 O43927 C-X-C motif chemokine 13 chr4 GO:0030336 Not Cancer Driver No 11 0.101 0 0 0.0 0
CYGB CYGB Q8WWM9 Cytoglobin chr17 GO:0030336 Not Cancer Driver No 32 0.168 47 5 0.106 0
CYP19A1_ENST00000396404 CYP19A1 P11511 Aromatase chr15 GO:0030336 Not Cancer Driver No 91 0.181 2 1 0.5 5
CYP1B1 CYP1B1 Q16678 Cytochrome P450 1B1 chr2 GO:0030336 Not Cancer Driver No 61 0.112 31 3 0.097 40
DAB2IP_ENST00000408936 DAB2IP Q5VWQ8 Disabled homolog 2-interacting protein chr9 GO:0030336 Not Cancer Driver No 131 0.11 681 68 0.1 0
DACH1_ENST00000619232 DACH1 Q9UI36 Dachshund homolog 1 chr13 GO:0030336 Not Cancer Driver No 157 0.207 641 134 0.209 0
DAG1_ENST00000515359 DAG1 Q14118 Dystroglycan 1 chr3 GO:0030336 Not Cancer Driver No 102 0.114 485 61 0.126 4
DCN DCN P07585 Decorin chr12 GO:0030336 Not Cancer Driver No 96 0.267 81 26 0.321 0
DDT_ENST00000350608 DDT P30046 D-dopachrome decarboxylase chr22 GO:0030336 Not Cancer Driver No 4 0.034 0 0 0.0 0
DLC1 DLC1 Q96QB1 Rho GTPase-activating protein 7 chr8 GO:0030336 Not Cancer Driver No 331 0.217 922 237 0.257 0
DLG5 DLG5 Q8TDM6 Disks large homolog 5 chr10 GO:0030336 Not Cancer Driver No 230 0.12 1119 135 0.121 0
DLL4 DLL4 Q9NR61 Delta-like protein 4 chr15 GO:0030336 Not Cancer Driver No 75 0.109 73 15 0.205 7
DNAJA4_ENST00000394852 DNAJA4 Q8WW22 DnaJ homolog subfamily A member 4 chr15 GO:0030336 Not Cancer Driver No 43 0.108 110 6 0.055 0
DPEP1 DPEP1 P16444 Dipeptidase 1 chr16 GO:0030336 Not Cancer Driver No 54 0.131 41 6 0.146 0
DPP4 DPP4 P27487 Dipeptidyl peptidase 4 chr2 GO:0030336 Not Cancer Driver No 151 0.197 8 1 0.125 0
DPYSL3_ENST00000398514 DPYSL3 Q14195 Dihydropyrimidinase-related protein 3 chr5 GO:0030336 Not Cancer Driver No 93 0.163 128 14 0.109 0
DRD2_ENST00000542968 DRD2 P14416 D(2) dopamine receptor chr11 GO:0030336 Not Cancer Driver No 127 0.287 124 45 0.363 0
DUSP1 DUSP1 P28562 Dual specificity protein phosphatase 1 chr5 GO:0030336 Not Cancer Driver No 31 0.084 7 0 0.0 0
DUSP10 DUSP10 Q9Y6W6 Dual specificity protein phosphatase 10 chr1 GO:0030336 Not Cancer Driver No 81 0.168 135 24 0.178 0
DUSP22_ENST00000344450 DUSP22 Q9NRW4 Dual specificity protein phosphatase 22 chr6 GO:0030336 Not Cancer Driver No 84 0.457 0 0 0.0 0
DUSP3 DUSP3 P51452 Dual specificity protein phosphatase 3 chr17 GO:0030336 Not Cancer Driver No 21 0.114 4 1 0.25 0
EMILIN1 EMILIN1 Q9Y6C2 EMILIN-1 chr2 GO:0030336 Not Cancer Driver No 125 0.123 669 69 0.103 0
EMILIN2 EMILIN2 Q9BXX0 EMILIN-2 chr18 GO:0030336 Not Cancer Driver No 158 0.15 617 94 0.152 0
ENG ENG P17813 Endoglin chr9 GO:0030336 Not Cancer Driver No 60 0.091 114 15 0.132 32
EPHA1 EPHA1 P21709 Ephrin type-A receptor 1 chr7 GO:0030336 Not Cancer Driver No 147 0.151 211 38 0.18 0
EPHA4_ENST00000409938 EPHA4 P54764 Ephrin type-A receptor 4 chr2 GO:0030336 Not Cancer Driver No 182 0.185 140 24 0.171 0
EPPK1 EPPK1 P58107 Epiplakin chr8 GO:0030336 Not Cancer Driver No 417 0.082 1336 67 0.05 0
EVL_ENST00000402714 EVL Q9UI08 Ena/VASP-like protein chr14 GO:0030336 Not Cancer Driver No 42 0.101 335 37 0.11 0
FAM19A5 TAFA5 Q7Z5A7 Chemokine-like protein TAFA-5 chr22 GO:0030336 Not Cancer Driver No 31 0.235 27 6 0.222 0
FGF2_ENST00000614010 FGF2 P09038 Fibroblast growth factor 2 chr4 GO:0030336 Not Cancer Driver No 18 0.062 183 5 0.027 0
FLCN FLCN Q8NFG4 Folliculin chr17 GO:0030336 Census, Compendium Yes 59 0.102 157 19 0.121 5
FOXO3 FOXO3 O43524 Forkhead box protein O3 chr6 GO:0030336 Census, Compendium Yes 70 0.104 595 68 0.114 0
FUZ FUZ Q9BT04 Protein fuzzy homolog chr19 GO:0030336 Not Cancer Driver No 38 0.091 43 4 0.093 0
GADD45A GADD45A P24522 Growth arrest and DNA damage-inducible protein GADD45 alpha chr1 GO:0030336 Not Cancer Driver No 10 0.061 39 5 0.128 0
GCSAM_ENST00000308910 GCSAM Q8N6F7 Germinal center-associated signaling and motility protein chr3 GO:0030336 Not Cancer Driver No 31 0.174 136 22 0.162 0
GJA1 GJA1 P17302 Gap junction alpha-1 protein chr6 GO:0030336 Not Cancer Driver No 86 0.225 110 26 0.236 50
GNA12 GNA12 Q03113 Guanine nucleotide-binding protein subunit alpha-12 chr7 GO:0030336 Not Cancer Driver No 41 0.108 20 0 0.0 0
GNA13 GNA13 Q14344 Guanine nucleotide-binding protein subunit alpha-13 chr17 GO:0030336 Compendium Yes 52 0.138 32 4 0.125 0
GNRH1_ENST00000421054 GNRH1 P01148 Progonadoliberin-1 chr8 GO:0030336 Not Cancer Driver No 17 0.185 29 7 0.241 0
GPR173 GPR173 Q9NS66 Probable G-protein coupled receptor 173 chrX GO:0030336 Not Cancer Driver No 57 0.153 12 0 0.0 0
GPR18_ENST00000397470 GPR18 Q14330 N-arachidonyl glycine receptor chr13 GO:0030336 Not Cancer Driver No 36 0.109 0 0 0.0 0
GREM1 GREM1 O60565 Gremlin-1 chr15 GO:0030336 Not Cancer Driver No 25 0.136 77 12 0.156 0
GTPBP4 GTPBP4 Q9BZE4 GTP-binding protein 4 chr10 GO:0030336 Not Cancer Driver No 79 0.125 232 34 0.147 0
HAS1 HAS1 Q92839 Hyaluronan synthase 1 chr19 GO:0030336 Not Cancer Driver No 115 0.199 9 0 0.0 0
HDAC5_ENST00000586802 HDAC5 Q9UQL6 Histone deacetylase 5 chr17 GO:0030336 Not Cancer Driver No 118 0.105 718 73 0.102 0
HMGB1_ENST00000405805 HMGB1 P09429 High mobility group protein B1 chr13 GO:0030336 Not Cancer Driver No 25 0.116 203 20 0.099 0
HMOX1 HMOX1 P09601 Heme oxygenase 1 chr22 GO:0030336 Not Cancer Driver No 46 0.16 81 13 0.16 0
HOXA7 HOXA7 P31268 Homeobox protein Hox-A7 chr7 GO:0030336 Not Cancer Driver No 60 0.261 71 15 0.211 0
HRG HRG P04196 Histidine-rich glycoprotein chr3 GO:0030336 Not Cancer Driver No 121 0.23 277 75 0.271 2
HYAL2_ENST00000357750 HYAL2 Q12891 Hyaluronidase-2 chr3 GO:0030336 Not Cancer Driver No 52 0.11 8 1 0.125 0
IFITM1_ENST00000528780 IFITM1 P13164 Interferon-induced transmembrane protein 1 chr11 GO:0030336 Not Cancer Driver No 19 0.152 0 0 0.0 0
IGFBP3_ENST00000275521 IGFBP3 P17936 Insulin-like growth factor-binding protein 3 chr7 GO:0030336 Not Cancer Driver No 41 0.141 103 25 0.243 0
IGFBP5 IGFBP5 P24593 Insulin-like growth factor-binding protein 5 chr2 GO:0030336 Not Cancer Driver No 27 0.099 112 17 0.152 0
IL24_ENST00000294984 IL24 Q13007 Interleukin-24 chr1 GO:0030336 Not Cancer Driver No 35 0.17 0 0 0.0 0
IL27RA IL27RA Q6UWB1 Interleukin-27 receptor subunit alpha chr19 GO:0030336 Not Cancer Driver No 91 0.143 167 23 0.138 0
IL4 IL4 P05112 Interleukin-4 chr5 GO:0030336 Not Cancer Driver No 18 0.118 0 0 0.0 0
ITGB1BP1_ENST00000355346 ITGB1BP1 O14713 Integrin beta-1-binding protein 1 chr2 GO:0030336 Not Cancer Driver No 26 0.13 58 11 0.19 0
JAG1 JAG1 P78504 Protein jagged-1 chr20 GO:0030336 Not Cancer Driver No 182 0.149 172 20 0.116 52
JUP JUP P14923 Junction plakoglobin chr17 GO:0030336 Not Cancer Driver No 112 0.15 241 37 0.154 0
KANK1_ENST00000382303 KANK1 Q14678 KN motif and ankyrin repeat domain-containing protein 1 chr9 GO:0030336 Not Cancer Driver No 183 0.135 804 100 0.124 0
KLRK1 KLRK1 P26718 NKG2-D type II integral membrane protein chr12 GO:0030336 Not Cancer Driver No 38 0.176 0 0 0.0 0
KRIT1_ENST00000394505 KRIT1 O00522 Krev interaction trapped protein 1 chr7 GO:0030336 Not Cancer Driver No 80 0.109 113 17 0.15 2
KRT16 KRT16 P08779 Keratin, type I cytoskeletal 16 chr17 GO:0030336 Not Cancer Driver No 83 0.175 152 28 0.184 16
LDLRAD4 LDLRAD4 O15165 Low-density lipoprotein receptor class A domain-containing protein 4 chr18 GO:0030336 Not Cancer Driver No 66 0.216 191 39 0.204 0
LIMCH1_ENST00000313860 LIMCH1 Q9UPQ0 LIM and calponin homology domains-containing protein 1 chr4 GO:0030336 Not Cancer Driver No 177 0.163 880 140 0.159 0
LRCH1_ENST00000389798 LRCH1 Q9Y2L9 Leucine-rich repeat and calponin homology domain-containing protein 1 chr13 GO:0030336 Not Cancer Driver No 95 0.13 380 41 0.108 0
LRP1 LRP1 Q07954 Prolow-density lipoprotein receptor-related protein 1 chr12 GO:0030336 Not Cancer Driver No 664 0.146 317 52 0.164 1
MAGI2 MAGI2 Q86UL8 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 chr7 GO:0030336 Not Cancer Driver No 305 0.21 1086 201 0.185 0
MAP2K5 MAP2K5 Q13163 Dual specificity mitogen-activated protein kinase kinase 5 chr15 GO:0030336 Not Cancer Driver No 40 0.089 85 10 0.118 0
MAPK15 MAPK15 Q8TD08 Mitogen-activated protein kinase 15 chr8 GO:0030336 Not Cancer Driver No 81 0.149 235 37 0.157 0
MARVELD3_ENST00000268485 MARVELD3 Q96A59 MARVEL domain-containing protein 3 chr16 GO:0030336 Not Cancer Driver No 40 0.1 179 10 0.056 0
MCC_ENST00000302475 MCC P23508 Colorectal mutant cancer protein chr5 GO:0030336 Not Cancer Driver No 136 0.164 589 92 0.156 0
MCTP1 MCTP1 Q6DN14 Multiple C2 and transmembrane domain-containing protein 1 chr5 GO:0030336 Not Cancer Driver No 162 0.162 323 29 0.09 0
MECP2_ENST00000303391 MECP2 P51608 Methyl-CpG-binding protein 2 chrX GO:0030336 Not Cancer Driver No 75 0.154 483 74 0.153 46
MEF2C_ENST00000504921 MEF2C Q06413 Myocyte-specific enhancer factor 2C chr5 GO:0030336 Not Cancer Driver No 92 0.195 408 81 0.199 0
MEOX2 MEOX2 P50222 Homeobox protein MOX-2 chr7 GO:0030336 Not Cancer Driver No 70 0.23 274 63 0.23 0
MIA3 MIA3 Q5JRA6 Transport and Golgi organization protein 1 homolog chr1 GO:0030336 Not Cancer Driver No 222 0.116 1490 178 0.119 0
MIF MIF P14174 Macrophage migration inhibitory factor chr22 GO:0030336 Not Cancer Driver No 4 0.035 0 0 0.0 0
MIIP MIIP Q5JXC2 Migration and invasion-inhibitory protein chr1 GO:0030336 Not Cancer Driver No 61 0.157 291 48 0.165 0
MITF_ENST00000448226 MITF O75030 Microphthalmia-associated transcription factor chr3 GO:0030336 Census Yes 80 0.152 408 69 0.169 7
MMRN2 MMRN2 Q9H8L6 Multimerin-2 chr10 GO:0030336 Not Cancer Driver No 98 0.103 420 49 0.117 0
MYOCD_ENST00000343344 MYOCD Q8IZQ8 Myocardin chr17 GO:0030336 Not Cancer Driver No 284 0.303 853 263 0.308 0
NAV3 NAV3 Q8IVL0 Neuron navigator 3 chr12 GO:0030336 Not Cancer Driver No 699 0.293 1823 548 0.301 0
NBL1_ENST00000602662 NBL1 P41271 Neuroblastoma suppressor of tumorigenicity 1 chr1 GO:0030336 Not Cancer Driver No 18 0.099 64 4 0.062 0
NDRG4_ENST00000570248 NDRG4 Q9ULP0 Protein NDRG4 chr16 GO:0030336 Not Cancer Driver No 44 0.125 90 11 0.122 0
NEXMIF_ENST00000616200 NEXMIF Q5QGS0 Neurite extension and migration factor chrX GO:0030336 Not Cancer Driver No 404 0.266 1054 292 0.277 0
NF1 NF1 P21359 Neurofibromin chr17 GO:0030336 Census, Compendium Yes 375 0.132 406 47 0.116 85
NF2 NF2 P35240 Merlin chr22 GO:0030336 Census, Compendium Yes 69 0.116 252 26 0.103 16
NFE2L2 NFE2L2 Q16236 Nuclear factor erythroid 2-related factor 2 chr2 GO:0030336 Census, Compendium Yes 228 0.377 402 62 0.154 4
NGFR NGFR P08138 Tumor necrosis factor receptor superfamily member 16 chr17 GO:0030336 Not Cancer Driver No 57 0.133 172 25 0.145 0
NISCH_ENST00000479054 NISCH Q9Y2I1 Nischarin chr3 GO:0030336 Not Cancer Driver No 160 0.106 418 43 0.103 0
NKX2-1_ENST00000518149 NKX2-1 P43699 Homeobox protein Nkx-2.1 chr14 GO:0030336 Census, Compendium Yes 41 0.111 334 39 0.117 7
NODAL NODAL Q96S42 Nodal homolog chr10 GO:0030336 Not Cancer Driver No 40 0.115 34 8 0.235 4
NOG NOG Q13253 Noggin chr17 GO:0030336 Not Cancer Driver No 22 0.095 86 9 0.105 20
NOTCH1 NOTCH1 P46531 Neurogenic locus notch homolog protein 1 chr9 GO:0030336 Census, Compendium Yes 363 0.142 686 87 0.127 3
NR2F2 NR2F2 P24468 COUP transcription factor 2 chr15 GO:0030336 Not Cancer Driver No 66 0.159 101 1 0.01 5
NRG1_ENST00000405005 NRG1 Q02297 Pro-neuregulin-1, membrane-bound isoform chr8 GO:0030336 Census, Compendium Yes 159 0.248 528 132 0.25 0
NRG3_ENST00000404547 NRG3 P56975 Pro-neuregulin-3, membrane-bound isoform chr10 GO:0030336 Not Cancer Driver No 227 0.315 425 134 0.315 0
OSBPL8 OSBPL8 Q9BZF1 Oxysterol-binding protein-related protein 8 chr12 GO:0030336 Not Cancer Driver No 105 0.118 401 37 0.092 0
PADI2 PADI2 Q9Y2J8 Protein-arginine deiminase type-2 chr1 GO:0030336 Not Cancer Driver No 121 0.182 60 18 0.3 0
PATZ1 PATZ1 Q9HBE1 POZ-, AT hook-, and zinc finger-containing protein 1 chr22 GO:0030336 Census Yes 91 0.132 301 38 0.126 0
PDCD10_ENST00000473645 PDCD10 Q9BUL8 Programmed cell death protein 10 chr3 GO:0030336 Not Cancer Driver No 32 0.151 25 4 0.16 0
PFN2 PFN2 P35080 Profilin-2 chr3 GO:0030336 Not Cancer Driver No 20 0.143 0 0 0.0 0
PHLDB2 PHLDB2 Q86SQ0 Pleckstrin homology-like domain family B member 2 chr3 GO:0030336 Not Cancer Driver No 235 0.188 1030 190 0.184 0
PIP5KL1 PIP5KL1 Q5T9C9 Phosphatidylinositol 4-phosphate 5-kinase-like protein 1 chr9 GO:0030336 Not Cancer Driver No 28 0.071 74 6 0.081 0
PLCB1 PLCB1 Q9NQ66 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 chr20 GO:0030336 Not Cancer Driver No 313 0.257 481 104 0.216 0
PLXNB3_ENST00000361971 PLXNB3 Q9ULL4 Plexin-B3 chrX GO:0030336 Not Cancer Driver No 217 0.114 358 37 0.103 0
PODN_ENST00000618387 PODN Q7Z5L7 Podocan chr1 GO:0030336 Not Cancer Driver No 126 0.206 107 13 0.121 0
PPARD_ENST00000360694 PPARD Q03181 Peroxisome proliferator-activated receptor delta chr6 GO:0030336 Not Cancer Driver No 72 0.163 69 7 0.101 0
PPARG PPARG P37231 Peroxisome proliferator-activated receptor gamma chr3 GO:0030336 Census Yes 72 0.143 44 4 0.091 3
PRKG1_ENST00000401604 PRKG1 Q13976 cGMP-dependent protein kinase 1 chr10 GO:0030336 Not Cancer Driver No 167 0.249 93 22 0.237 1
PTEN PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 GO:0030336 Census, Compendium Yes 505 1.253 76 4 0.053 41
PTGER4 PTGER4 P35408 Prostaglandin E2 receptor EP4 subtype chr5 GO:0030336 Not Cancer Driver No 81 0.166 118 17 0.144 0
PTPN23 PTPN23 Q9H3S7 Tyrosine-protein phosphatase non-receptor type 23 chr3 GO:0030336 Not Cancer Driver No 147 0.09 796 71 0.089 2
PTPRG PTPRG P23470 Receptor-type tyrosine-protein phosphatase gamma chr3 GO:0030336 Not Cancer Driver No 212 0.147 465 61 0.131 0
PTPRJ PTPRJ Q12913 Receptor-type tyrosine-protein phosphatase eta chr11 GO:0030336 Not Cancer Driver No 184 0.138 401 61 0.152 0
PTPRK_ENST00000368215 PTPRK Q15262 Receptor-type tyrosine-protein phosphatase kappa chr6 GO:0030336 Census, Compendium Yes 292 0.203 302 57 0.189 0
PTPRM_ENST00000332175 PTPRM P28827 Receptor-type tyrosine-protein phosphatase mu chr18 GO:0030336 Not Cancer Driver No 256 0.176 365 60 0.164 0
PTPRR PTPRR Q15256 Receptor-type tyrosine-protein phosphatase R chr12 GO:0030336 Not Cancer Driver No 172 0.262 73 28 0.384 0
PTPRT_ENST00000373187 PTPRT O14522 Receptor-type tyrosine-protein phosphatase T chr20 GO:0030336 Census, Compendium Yes 535 0.371 299 125 0.418 0
PTPRU PTPRU Q92729 Receptor-type tyrosine-protein phosphatase U chr1 GO:0030336 Not Cancer Driver No 248 0.172 325 64 0.197 0
RABGEF1_ENST00000284957 RABGEF1 Q9UJ41 Rab5 GDP/GTP exchange factor chr7 GO:0030336 Not Cancer Driver No 73 0.149 175 35 0.2 0
RAC1_ENST00000348035 RAC1 P63000 Ras-related C3 botulinum toxin substrate 1 chr7 GO:0030336 Census, Compendium Yes 66 0.344 2 1 0.5 6
RAP2A RAP2A P10114 Ras-related protein Rap-2a chr13 GO:0030336 Not Cancer Driver No 15 0.082 9 0 0.0 0
RAP2B RAP2B P61225 Ras-related protein Rap-2b chr3 GO:0030336 Not Cancer Driver No 22 0.12 0 0 0.0 0
RAP2C_ENST00000370874 RAP2C Q9Y3L5 Ras-related protein Rap-2c chrX GO:0030336 Not Cancer Driver No 32 0.175 8 2 0.25 0
RECK RECK O95980 Reversion-inducing cysteine-rich protein with Kazal motifs chr9 GO:0030336 Not Cancer Driver No 115 0.118 9 2 0.222 0
RGCC RGCC Q9H4X1 Regulator of cell cycle RGCC chr13 GO:0030336 Not Cancer Driver No 9 0.066 81 7 0.086 0
RHOA RHOA P61586 Transforming protein RhoA chr3 GO:0030336 Census, Compendium Yes 99 0.513 46 13 0.283 2
RHOB RHOB P62745 Rho-related GTP-binding protein RhoB chr2 GO:0030336 Not Cancer Driver No 52 0.265 19 2 0.105 0
RIN3 RIN3 Q8TB24 Ras and Rab interactor 3 chr14 GO:0030336 Not Cancer Driver No 137 0.139 417 61 0.146 0
RIPOR2_ENST00000259698 RIPOR2 Q9Y4F9 Rho family-interacting cell polarization regulator 2 chr6 GO:0030336 Not Cancer Driver No 131 0.123 421 76 0.181 0
RNF20 RNF20 Q5VTR2 E3 ubiquitin-protein ligase BRE1A chr9 GO:0030336 Not Cancer Driver No 126 0.129 561 64 0.114 0
RNF41_ENST00000615206 RNF41 Q9H4P4 E3 ubiquitin-protein ligase NRDP1 chr12 GO:0030336 Not Cancer Driver No 44 0.139 33 2 0.061 0
ROBO1 ROBO1 Q9Y6N7 Roundabout homolog 1 chr3 GO:0030336 Not Cancer Driver No 353 0.214 1122 234 0.209 0
RRAS RRAS P10301 Ras-related protein R-Ras chr19 GO:0030336 Not Cancer Driver No 25 0.115 71 6 0.085 0
S1PR2 S1PR2 O95136 Sphingosine 1-phosphate receptor 2 chr19 GO:0030336 Not Cancer Driver No 38 0.108 16 3 0.188 2
SCAI_ENST00000336505 SCAI Q8N9R8 Protein SCAI chr9 GO:0030336 Not Cancer Driver No 95 0.157 117 13 0.111 0
SEMA3A SEMA3A Q14563 Semaphorin-3A chr7 GO:0030336 Not Cancer Driver No 195 0.253 164 46 0.28 10
SEMA6D_ENST00000536845 SEMA6D Q8NFY4 Semaphorin-6D chr15 GO:0030336 Not Cancer Driver No 212 0.198 475 99 0.208 0
SERPINE1 SERPINE1 P05121 Plasminogen activator inhibitor 1 chr7 GO:0030336 Not Cancer Driver No 78 0.194 7 2 0.286 0
SERPINF1 SERPINF1 P36955 Pigment epithelium-derived factor chr17 GO:0030336 Not Cancer Driver No 51 0.122 57 5 0.088 0
SFRP1 SFRP1 Q8N474 Secreted frizzled-related protein 1 chr8 GO:0030336 Not Cancer Driver No 40 0.127 39 7 0.179 0
SFRP2 SFRP2 Q96HF1 Secreted frizzled-related protein 2 chr4 GO:0030336 Not Cancer Driver No 47 0.159 1 0 0.0 0
SHH SHH Q15465 Sonic hedgehog protein chr7 GO:0030336 Not Cancer Driver No 56 0.121 139 14 0.101 81
SINHCAF_ENST00000454658 SINHCAF Q9NP50 SIN3-HDAC complex-associated factor chr12 GO:0030336 Not Cancer Driver No 24 0.109 108 10 0.093 0
SLAMF8 SLAMF8 Q9P0V8 SLAM family member 8 chr1 GO:0030336 Not Cancer Driver No 63 0.221 20 2 0.1 0
SLC9A3R1 SLC9A3R1 O14745 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 chr17 GO:0030336 Not Cancer Driver No 19 0.053 318 16 0.05 4
SLIT2 SLIT2 O94813 Slit homolog 2 protein chr4 GO:0030336 Not Cancer Driver No 428 0.28 31 13 0.419 0
SLURP1 SLURP1 P55000 Secreted Ly-6/uPAR-related protein 1 chr8 GO:0030336 Not Cancer Driver No 19 0.184 0 0 0.0 8
SMAD7 SMAD7 O15105 Mothers against decapentaplegic homolog 7 chr18 GO:0030336 Not Cancer Driver No 40 0.094 139 0 0.0 0
SP100_ENST00000264052 SP100 P23497 Nuclear autoantigen Sp-100 chr2 GO:0030336 Not Cancer Driver No 136 0.155 680 101 0.149 0
SPRED1 SPRED1 Q7Z699 Sprouty-related, EVH1 domain-containing protein 1 chr15 GO:0030336 Not Cancer Driver No 71 0.16 194 35 0.18 2
SRF SRF P11831 Serum response factor chr6 GO:0030336 Not Cancer Driver No 44 0.087 443 42 0.095 0
SRGAP1 SRGAP1 Q7Z6B7 SLIT-ROBO Rho GTPase-activating protein 1 chr12 GO:0030336 Not Cancer Driver No 191 0.176 553 87 0.157 4
SRGAP2 SRGAP2 O75044 SLIT-ROBO Rho GTPase-activating protein 2 chr1 GO:0030336 Not Cancer Driver No 122 0.114 541 71 0.131 0
SRGAP2B_ENST00000612199 SRGAP2B P0DMP2 SLIT-ROBO Rho GTPase-activating protein 2B chr1 GO:0030336 Not Cancer Driver No 12 0.026 127 0 0.0 0
SRGAP2C SRGAP2C P0DJJ0 SLIT-ROBO Rho GTPase-activating protein 2C chr1 GO:0030336 Not Cancer Driver No 2 0.004 135 2 0.015 0
SRGAP3 SRGAP3 O43295 SLIT-ROBO Rho GTPase-activating protein 3 chr3 GO:0030336 Census, Compendium Yes 195 0.177 549 97 0.177 0
STAP1_ENST00000396225 STAP1 Q9ULZ2 Signal-transducing adaptor protein 1 chr4 GO:0030336 Not Cancer Driver No 66 0.224 103 18 0.175 0
STARD13 STARD13 Q9Y3M8 StAR-related lipid transfer protein 13 chr13 GO:0030336 Not Cancer Driver No 177 0.159 494 78 0.158 0
STAT3 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 GO:0030336 Census, Compendium Yes 110 0.143 152 15 0.099 19
STC1 STC1 P52823 Stanniocalcin-1 chr8 GO:0030336 Not Cancer Driver No 59 0.239 58 12 0.207 0
STK24 STK24 Q9Y6E0 Serine/threonine-protein kinase 24 chr13 GO:0030336 Not Cancer Driver No 67 0.151 118 16 0.136 0
STK26 STK26 Q9P289 Serine/threonine-protein kinase 26 chrX GO:0030336 Not Cancer Driver No 62 0.149 119 18 0.151 0
SULF1_ENST00000458141 SULF1 Q8IWU6 Extracellular sulfatase Sulf-1 chr8 GO:0030336 Not Cancer Driver No 246 0.282 269 71 0.264 0
SVBP_ENST00000372522 SVBP Q8N300 Small vasohibin-binding protein chr1 GO:0030336 Not Cancer Driver No 7 0.106 66 7 0.106 0
SYNJ2BP SYNJ2BP P57105 Synaptojanin-2-binding protein chr14 GO:0030336 Not Cancer Driver No 27 0.186 12 4 0.333 0
TACSTD2 TACSTD2 P09758 Tumor-associated calcium signal transducer 2 chr1 GO:0030336 Not Cancer Driver No 22 0.068 27 1 0.037 0
TBX5 TBX5 Q99593 T-box transcription factor TBX5 chr12 GO:0030336 Not Cancer Driver No 155 0.299 351 113 0.322 5
TBXA2R_ENST00000375190 TBXA2R P21731 Thromboxane A2 receptor chr19 GO:0030336 Not Cancer Driver No 47 0.137 17 4 0.235 1
TCAF1 TCAF1 Q9Y4C2 TRPM8 channel-associated factor 1 chr7 GO:0030336 Not Cancer Driver No 43 0.047 18 3 0.167 0
TGFB1 TGFB1 P01137 Transforming growth factor beta-1 proprotein chr19 GO:0030336 Not Cancer Driver No 41 0.105 41 4 0.098 10
THBS1 THBS1 P07996 Thrombospondin-1 chr15 GO:0030336 Not Cancer Driver No 188 0.161 320 58 0.181 0
THY1 THY1 P04216 Thy-1 membrane glycoprotein chr11 GO:0030336 Not Cancer Driver No 24 0.149 5 0 0.0 0
TIE1 TIE1 P35590 Tyrosine-protein kinase receptor Tie-1 chr1 GO:0030336 Not Cancer Driver No 200 0.176 223 46 0.206 0
TIMP1 TIMP1 P01033 Metalloproteinase inhibitor 1 chrX GO:0030336 Not Cancer Driver No 25 0.121 0 0 0.0 0
TMEFF2 TMEFF2 Q9UIK5 Tomoregulin-2 chr2 GO:0030336 Not Cancer Driver No 81 0.217 68 8 0.118 0
TMIGD3_ENST00000369717 TMIGD3 P0DMS9 Transmembrane domain-containing protein TMIGD3 chr1 GO:0030336 Not Cancer Driver No 49 0.184 57 10 0.175 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:0030336 Not Cancer Driver No 24 0.103 45 3 0.067 0
TNFAIP6 TNFAIP6 P98066 Tumor necrosis factor-inducible gene 6 protein chr2 GO:0030336 Not Cancer Driver No 62 0.224 13 5 0.385 0
TNN TNN Q9UQP3 Tenascin-N chr1 GO:0030336 Not Cancer Driver No 426 0.328 637 231 0.363 0
TP53INP1 TP53INP1 Q96A56 Tumor protein p53-inducible nuclear protein 1 chr8 GO:0030336 Not Cancer Driver No 32 0.133 134 20 0.149 0
TPM1_ENST00000403994 TPM1 P09493 Tropomyosin alpha-1 chain chr15 GO:0030336 Not Cancer Driver No 33 0.116 234 29 0.124 8
TRIB1 TRIB1 Q96RU8 Tribbles homolog 1 chr8 GO:0030336 Not Cancer Driver No 47 0.126 91 5 0.055 0
VASH1 VASH1 Q7L8A9 Tubulinyl-Tyr carboxypeptidase 1 chr14 GO:0030336 Not Cancer Driver No 39 0.107 215 18 0.084 0
VCL VCL P18206 Vinculin chr10 GO:0030336 Not Cancer Driver No 114 0.101 673 80 0.119 2
WASL WASL O00401 Neural Wiskott-Aldrich syndrome protein chr7 GO:0030336 Not Cancer Driver No 72 0.143 394 57 0.145 0
WDR63 DNAI3 Q8IWG1 Dynein axonemal intermediate chain 3 chr1 GO:0030336 Not Cancer Driver No 129 0.145 210 31 0.148 0
WNT11 WNT11 O96014 Protein Wnt-11 chr11 GO:0030336 Not Cancer Driver No 55 0.155 59 4 0.068 0
WNT4 WNT4 P56705 Protein Wnt-4 chr1 GO:0030336 Not Cancer Driver No 30 0.085 39 4 0.103 4
ZMYND8_ENST00000311275 ZMYND8 Q9ULU4 Protein kinase C-binding protein 1 chr20 GO:0030336 Not Cancer Driver No 176 0.148 830 124 0.149 0