Total number of protein in "GO:0030295" GO term: 64
Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ABI1 | ABI1 | Q8IZP0 | Abl interactor 1 | chr10 | GO:0030295 | Census, Compendium | Yes | 55 | 0.108 | 360 | 39 | 0.108 | 0 |
AFAP1L2 | AFAP1L2 | Q8N4X5 | Actin filament-associated protein 1-like 2 | chr10 | GO:0030295 | Not Cancer Driver | No | 86 | 0.105 | 558 | 59 | 0.106 | 0 |
AGAP2 | AGAP2 | Q99490 | Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 | chr12 | GO:0030295 | Not Cancer Driver | No | 133 | 0.112 | 754 | 81 | 0.107 | 0 |
ALKAL1 | ALKAL1 | Q6UXT8 | ALK and LTK ligand 1 | chr8 | GO:0030295 | Not Cancer Driver | No | 18 | 0.14 | 49 | 3 | 0.061 | 0 |
ALKAL2 | ALKAL2 | Q6UX46 | ALK and LTK ligand 2 | chr2 | GO:0030295 | Not Cancer Driver | No | 7 | 0.046 | 31 | 0 | 0.0 | 0 |
ANGPT4 | ANGPT4 | Q9Y264 | Angiopoietin-4 | chr20 | GO:0030295 | Not Cancer Driver | No | 104 | 0.207 | 150 | 32 | 0.213 | 0 |
CAB39 | CAB39 | Q9Y376 | Calcium-binding protein 39 | chr2 | GO:0030295 | Not Cancer Driver | No | 31 | 0.091 | 43 | 5 | 0.116 | 0 |
CCNB1 | CCNB1 | P14635 | G2/mitotic-specific cyclin-B1 | chr5 | GO:0030295 | Not Cancer Driver | No | 49 | 0.113 | 145 | 14 | 0.097 | 0 |
CCNK | CCNK | O75909 | Cyclin-K | chr14 | GO:0030295 | Not Cancer Driver | No | 39 | 0.067 | 347 | 15 | 0.043 | 1 |
CCNT1 | CCNT1 | O60563 | Cyclin-T1 | chr12 | GO:0030295 | Not Cancer Driver | No | 85 | 0.117 | 495 | 61 | 0.123 | 0 |
CCNT2 | CCNT2 | O60583 | Cyclin-T2 | chr2 | GO:0030295 | Not Cancer Driver | No | 76 | 0.104 | 471 | 52 | 0.11 | 0 |
CCNY | CCNY | Q8ND76 | Cyclin-Y | chr10 | GO:0030295 | Not Cancer Driver | No | 38 | 0.111 | 94 | 6 | 0.064 | 0 |
CCNYL1 | CCNYL1 | Q8N7R7 | Cyclin-Y-like protein 1 | chr2 | GO:0030295 | Not Cancer Driver | No | 31 | 0.086 | 100 | 8 | 0.08 | 0 |
CDK5R1 | CDK5R1 | Q15078 | Cyclin-dependent kinase 5 activator 1 | chr17 | GO:0030295 | Not Cancer Driver | No | 35 | 0.114 | 103 | 16 | 0.155 | 0 |
CDK5R2 | CDK5R2 | Q13319 | Cyclin-dependent kinase 5 activator 2 | chr2 | GO:0030295 | Not Cancer Driver | No | 14 | 0.038 | 204 | 5 | 0.025 | 0 |
CDKN1A_ENST00000373711 | CDKN1A | P38936 | Cyclin-dependent kinase inhibitor 1 | chr6 | GO:0030295 | Census, Compendium | Yes | 48 | 0.293 | 121 | 30 | 0.248 | 0 |
CKS1B | CKS1B | P61024 | Cyclin-dependent kinases regulatory subunit 1 | chr1 | GO:0030295 | Not Cancer Driver | No | 10 | 0.127 | 10 | 0 | 0.0 | 0 |
CKS2 | CKS2 | P33552 | Cyclin-dependent kinases regulatory subunit 2 | chr9 | GO:0030295 | Not Cancer Driver | No | 9 | 0.114 | 10 | 2 | 0.2 | 0 |
DAXX_ENST00000266000 | DAXX | Q9UER7 | Death domain-associated protein 6 | chr6 | GO:0030295 | Census, Compendium | Yes | 106 | 0.143 | 549 | 81 | 0.148 | 0 |
DBF4B | DBF4B | Q8NFT6 | Protein DBF4 homolog B | chr17 | GO:0030295 | Not Cancer Driver | No | 68 | 0.111 | 311 | 22 | 0.071 | 0 |
DGKQ | DGKQ | P52824 | Diacylglycerol kinase theta | chr4 | GO:0030295 | Not Cancer Driver | No | 56 | 0.059 | 264 | 11 | 0.042 | 0 |
DUSP19 | DUSP19 | Q8WTR2 | Dual specificity protein phosphatase 19 | chr2 | GO:0030295 | Not Cancer Driver | No | 34 | 0.157 | 15 | 5 | 0.333 | 0 |
EFNA5 | EFNA5 | P52803 | Ephrin-A5 | chr5 | GO:0030295 | Not Cancer Driver | No | 34 | 0.149 | 25 | 6 | 0.24 | 0 |
EGF | EGF | P01133 | Pro-epidermal growth factor | chr4 | GO:0030295 | Not Cancer Driver | No | 184 | 0.152 | 191 | 25 | 0.131 | 1 |
EPO | EPO | P01588 | Erythropoietin | chr7 | GO:0030295 | Not Cancer Driver | No | 27 | 0.14 | 9 | 1 | 0.111 | 1 |
ERBB3 | ERBB3 | P21860 | Receptor tyrosine-protein kinase erbB-3 | chr12 | GO:0030295 | Census, Compendium | Yes | 298 | 0.222 | 396 | 70 | 0.177 | 3 |
ERCC6 | ERCC6 | Q03468 | DNA excision repair protein ERCC-6 | chr10 | GO:0030295 | Not Cancer Driver | No | 211 | 0.141 | 829 | 117 | 0.141 | 9 |
FGF13_ENST00000315930 | FGF13 | Q92913 | Fibroblast growth factor 13 | chrX | GO:0030295 | Not Cancer Driver | No | 70 | 0.286 | 96 | 33 | 0.344 | 2 |
GAS6 | GAS6 | Q14393 | Growth arrest-specific protein 6 | chr13 | GO:0030295 | Not Cancer Driver | No | 82 | 0.121 | 42 | 6 | 0.143 | 0 |
GHRL_ENST00000457360 | GHRL | Q9UBU3 | Appetite-regulating hormone | chr3 | GO:0030295 | Not Cancer Driver | No | 20 | 0.171 | 52 | 11 | 0.212 | 0 |
GPRC5A | GPRC5A | Q8NFJ5 | Retinoic acid-induced protein 3 | chr12 | GO:0030295 | Not Cancer Driver | No | 43 | 0.12 | 19 | 4 | 0.211 | 0 |
GPRC5B_ENST00000569479 | GPRC5B | Q9NZH0 | G-protein coupled receptor family C group 5 member B | chr16 | GO:0030295 | Not Cancer Driver | No | 82 | 0.203 | 75 | 19 | 0.253 | 0 |
GPRC5C_ENST00000392629 | GPRC5C | Q9NQ84 | G-protein coupled receptor family C group 5 member C | chr17 | GO:0030295 | Not Cancer Driver | No | 77 | 0.175 | 58 | 15 | 0.259 | 0 |
GPRC5D | GPRC5D | Q9NZD1 | G-protein coupled receptor family C group 5 member D | chr12 | GO:0030295 | Not Cancer Driver | No | 32 | 0.093 | 32 | 1 | 0.031 | 0 |
GREM1 | GREM1 | O60565 | Gremlin-1 | chr15 | GO:0030295 | Not Cancer Driver | No | 25 | 0.136 | 77 | 12 | 0.156 | 0 |
GRM5 | GRM5 | P41594 | Metabotropic glutamate receptor 5 | chr11 | GO:0030295 | Not Cancer Driver | No | 312 | 0.257 | 323 | 51 | 0.158 | 0 |
MADD | MADD | Q8WXG6 | MAP kinase-activating death domain protein | chr11 | GO:0030295 | Not Cancer Driver | No | 207 | 0.126 | 723 | 81 | 0.112 | 4 |
MAP2K1 | MAP2K1 | Q02750 | Dual specificity mitogen-activated protein kinase kinase 1 | chr15 | GO:0030295 | Census, Compendium | Yes | 94 | 0.239 | 96 | 24 | 0.25 | 6 |
MARK2 | MARK2 | Q7KZI7 | Serine/threonine-protein kinase MARK2 | chr11 | GO:0030295 | Compendium | Yes | 124 | 0.157 | 445 | 70 | 0.157 | 0 |
MNAT1 | MNAT1 | P51948 | CDK-activating kinase assembly factor MAT1 | chr14 | GO:0030295 | Not Cancer Driver | No | 23 | 0.074 | 64 | 2 | 0.031 | 0 |
MOB1A | MOB1A | Q9H8S9 | MOB kinase activator 1A | chr2 | GO:0030295 | Not Cancer Driver | No | 16 | 0.074 | 10 | 2 | 0.2 | 0 |
MOB1B_ENST00000309395 | MOB1B | Q7L9L4 | MOB kinase activator 1B | chr4 | GO:0030295 | Not Cancer Driver | No | 17 | 0.079 | 7 | 0 | 0.0 | 0 |
MOB2_ENST00000614710 | MOB2 | Q70IA6 | MOB kinase activator 2 | chr11 | GO:0030295 | Not Cancer Driver | No | 22 | 0.093 | 46 | 0 | 0.0 | 0 |
MOB3A | MOB3A | Q96BX8 | MOB kinase activator 3A | chr19 | GO:0030295 | Not Cancer Driver | No | 26 | 0.12 | 16 | 1 | 0.062 | 0 |
MOB3B | MOB3B | Q86TA1 | MOB kinase activator 3B | chr9 | GO:0030295 | Not Cancer Driver | No | 29 | 0.134 | 16 | 2 | 0.125 | 0 |
MOB3C_ENST00000371940 | MOB3C | Q70IA8 | MOB kinase activator 3C | chr1 | GO:0030295 | Not Cancer Driver | No | 38 | 0.176 | 1 | 0 | 0.0 | 0 |
MT3 | MT3 | P25713 | Metallothionein-3 | chr16 | GO:0030295 | Not Cancer Driver | No | 7 | 0.103 | 0 | 0 | 0.0 | 0 |
NCKAP1L | NCKAP1L | P55160 | Nck-associated protein 1-like | chr12 | GO:0030295 | Not Cancer Driver | No | 247 | 0.219 | 51 | 10 | 0.196 | 4 |
NRG1_ENST00000405005 | NRG1 | Q02297 | Pro-neuregulin-1, membrane-bound isoform | chr8 | GO:0030295 | Census, Compendium | Yes | 159 | 0.248 | 528 | 132 | 0.25 | 0 |
NRG3_ENST00000404547 | NRG3 | P56975 | Pro-neuregulin-3, membrane-bound isoform | chr10 | GO:0030295 | Not Cancer Driver | No | 227 | 0.315 | 425 | 134 | 0.315 | 0 |
PAK2 | PAK2 | Q13177 | Serine/threonine-protein kinase PAK 2 | chr3 | GO:0030295 | Compendium | Yes | 89 | 0.17 | 242 | 49 | 0.202 | 0 |
PIK3CA | PIK3CA | P42336 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | chr3 | GO:0030295 | Census, Compendium | Yes | 1669 | 1.563 | 38 | 11 | 0.289 | 30 |
PRKAG2 | PRKAG2 | Q9UGJ0 | 5'-AMP-activated protein kinase subunit gamma-2 | chr7 | GO:0030295 | Not Cancer Driver | No | 76 | 0.134 | 240 | 45 | 0.188 | 7 |
RGCC | RGCC | Q9H4X1 | Regulator of cell cycle RGCC | chr13 | GO:0030295 | Not Cancer Driver | No | 9 | 0.066 | 81 | 7 | 0.086 | 0 |
RPLP1 | RPLP1 | P05386 | 60S acidic ribosomal protein P1 | chr15 | GO:0030295 | Not Cancer Driver | No | 6 | 0.053 | 45 | 2 | 0.044 | 0 |
RPTOR | RPTOR | Q8N122 | Regulatory-associated protein of mTOR | chr17 | GO:0030295 | Not Cancer Driver | No | 176 | 0.132 | 241 | 21 | 0.087 | 0 |
SPDYA_ENST00000379579 | SPDYA | Q5MJ70 | Speedy protein A | chr2 | GO:0030295 | Not Cancer Driver | No | 39 | 0.125 | 119 | 11 | 0.092 | 0 |
STK11 | STK11 | Q15831 | Serine/threonine-protein kinase STK11 | chr19 | GO:0030295 | Census, Compendium | Yes | 75 | 0.173 | 135 | 14 | 0.104 | 9 |
STRADA | STRADA | Q7RTN6 | STE20-related kinase adapter protein alpha | chr17 | GO:0030295 | Not Cancer Driver | No | 49 | 0.114 | 118 | 14 | 0.119 | 0 |
TAL1 | TAL1 | P17542 | T-cell acute lymphocytic leukemia protein 1 | chr1 | GO:0030295 | Census | Yes | 54 | 0.163 | 305 | 53 | 0.174 | 0 |
TOM1L1 | TOM1L1 | O75674 | TOM1-like protein 1 | chr17 | GO:0030295 | Not Cancer Driver | No | 51 | 0.107 | 268 | 29 | 0.108 | 0 |
TPX2 | TPX2 | Q9ULW0 | Targeting protein for Xklp2 | chr20 | GO:0030295 | Not Cancer Driver | No | 92 | 0.123 | 695 | 86 | 0.124 | 0 |
WNK1_ENST00000315939 | WNK1 | Q9H4A3 | Serine/threonine-protein kinase WNK1 | chr12 | GO:0030295 | Not Cancer Driver | No | 278 | 0.117 | 1959 | 223 | 0.114 | 0 |
WNT11 | WNT11 | O96014 | Protein Wnt-11 | chr11 | GO:0030295 | Not Cancer Driver | No | 55 | 0.155 | 59 | 4 | 0.068 | 0 |