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Total number of protein in "GO:0030234" GO term:  392

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABCE1 ABCE1 P61221 ATP-binding cassette sub-family E member 1 chr4 GO:0030234 Not Cancer Driver No 74 0.124 36 6 0.167 0
ABI1 ABI1 Q8IZP0 Abl interactor 1 chr10 GO:0030234 Census, Compendium Yes 55 0.108 360 39 0.108 0
ADGRV1_ENST00000645211 ADGRV1 Q8WXG9 Adhesion G-protein coupled receptor V1 chr5 GO:0030234 Not Cancer Driver No 1124 0.178 496 77 0.155 2
ADRM1 ADRM1 Q16186 Proteasomal ubiquitin receptor ADRM1 chr20 GO:0030234 Not Cancer Driver No 49 0.12 296 40 0.135 0
AFAP1L2 AFAP1L2 Q8N4X5 Actin filament-associated protein 1-like 2 chr10 GO:0030234 Not Cancer Driver No 86 0.105 558 59 0.106 0
AGAP2 AGAP2 Q99490 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 chr12 GO:0030234 Not Cancer Driver No 133 0.112 754 81 0.107 0
AHSG AHSG P02765 Alpha-2-HS-glycoprotein chr3 GO:0030234 Not Cancer Driver No 74 0.202 131 41 0.313 0
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:0030234 Census, Compendium Yes 108 0.225 158 24 0.152 4
ALK ALK Q9UM73 ALK tyrosine kinase receptor chr2 GO:0030234 Census, Compendium Yes 303 0.187 575 114 0.198 16
ALKAL1 ALKAL1 Q6UXT8 ALK and LTK ligand 1 chr8 GO:0030234 Not Cancer Driver No 18 0.14 49 3 0.061 0
ALKAL2 ALKAL2 Q6UX46 ALK and LTK ligand 2 chr2 GO:0030234 Not Cancer Driver No 7 0.046 31 0 0.0 0
ANGPT4 ANGPT4 Q9Y264 Angiopoietin-4 chr20 GO:0030234 Not Cancer Driver No 104 0.207 150 32 0.213 0
ANGPTL3 ANGPTL3 Q9Y5C1 Angiopoietin-related protein 3 chr1 GO:0030234 Not Cancer Driver No 52 0.113 154 26 0.169 0
ANXA1_ENST00000257497 ANXA1 P04083 Annexin A1 chr9 GO:0030234 Not Cancer Driver No 59 0.171 61 12 0.197 0
ANXA2_ENST00000396024 ANXA2 P07355 Annexin A2 chr15 GO:0030234 Not Cancer Driver No 49 0.145 20 4 0.2 0
ANXA3 ANXA3 P12429 Annexin A3 chr4 GO:0030234 Not Cancer Driver No 53 0.164 22 4 0.182 0
ANXA4 ANXA4 P09525 Annexin A4 chr2 GO:0030234 Not Cancer Driver No 47 0.147 41 6 0.146 0
ANXA5 ANXA5 P08758 Annexin A5 chr4 GO:0030234 Not Cancer Driver No 50 0.156 33 5 0.152 0
ANXA9 ANXA9 O76027 Annexin A9 chr1 GO:0030234 Not Cancer Driver No 52 0.151 42 7 0.167 0
APAF1 APAF1 O14727 Apoptotic protease-activating factor 1 chr12 GO:0030234 Not Cancer Driver No 127 0.102 17 1 0.059 0
APH1A APH1A Q96BI3 Gamma-secretase subunit APH-1A chr1 GO:0030234 Not Cancer Driver No 32 0.121 0 0 0.0 0
APH1B APH1B Q8WW43 Gamma-secretase subunit APH-1B chr15 GO:0030234 Not Cancer Driver No 21 0.082 0 0 0.0 0
APOA1_ENST00000375320 APOA1 P02647 Apolipoprotein A-I chr11 GO:0030234 Not Cancer Driver No 28 0.105 131 8 0.061 3
APOA2 APOA2 P02652 Apolipoprotein A-II chr1 GO:0030234 Not Cancer Driver No 13 0.13 0 0 0.0 0
APOA4 APOA4 P06727 Apolipoprotein A-IV chr11 GO:0030234 Not Cancer Driver No 77 0.194 298 65 0.218 0
APOA5 APOA5 Q6Q788 Apolipoprotein A-V chr11 GO:0030234 Not Cancer Driver No 51 0.139 178 26 0.146 0
APOC1_ENST00000588802 APOC1 P02654 Apolipoprotein C-I chr19 GO:0030234 Not Cancer Driver No 12 0.145 9 1 0.111 0
APOC2 APOC2 P02655 Apolipoprotein C-II chr19 GO:0030234 Not Cancer Driver No 8 0.079 14 2 0.143 1
APOC3 APOC3 P02656 Apolipoprotein C-III chr11 GO:0030234 Not Cancer Driver No 14 0.141 12 2 0.167 1
APOE APOE P02649 Apolipoprotein E chr19 GO:0030234 Not Cancer Driver No 25 0.079 124 6 0.048 12
APOH APOH P02749 Beta-2-glycoprotein 1 chr17 GO:0030234 Not Cancer Driver No 67 0.194 0 0 0.0 0
APP APP P05067 Amyloid-beta precursor protein chr21 GO:0030234 Not Cancer Driver No 128 0.166 418 71 0.17 17
ARHGAP6 ARHGAP6 O43182 Rho GTPase-activating protein 6 chrX GO:0030234 Not Cancer Driver No 168 0.172 680 118 0.174 0
ARHGDIA_ENST00000580685 ARHGDIA P52565 Rho GDP-dissociation inhibitor 1 chr17 GO:0030234 Not Cancer Driver No 25 0.123 50 6 0.12 0
ARHGDIB ARHGDIB P52566 Rho GDP-dissociation inhibitor 2 chr12 GO:0030234 Not Cancer Driver No 33 0.164 92 13 0.141 0
ARHGDIG ARHGDIG Q99819 Rho GDP-dissociation inhibitor 3 chr16 GO:0030234 Not Cancer Driver No 11 0.049 13 1 0.077 0
ATP2A3_ENST00000397041 ATP2A3 Q93084 Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 chr17 GO:0030234 Not Cancer Driver No 130 0.13 147 16 0.109 0
ATP6V1H_ENST00000396774 ATP6V1H Q9UI12 V-type proton ATPase subunit H chr8 GO:0030234 Not Cancer Driver No 76 0.157 35 2 0.057 0
AUP1 AUP1 Q9Y679 Lipid droplet-regulating VLDL assembly factor AUP1 chr2 GO:0030234 Not Cancer Driver No 41 0.1 122 13 0.107 0
AVP AVP P01185 Vasopressin-neurophysin 2-copeptin chr20 GO:0030234 Not Cancer Driver No 14 0.085 26 0 0.0 39
AZIN1 AZIN1 O14977 Antizyme inhibitor 1 chr8 GO:0030234 Not Cancer Driver No 39 0.087 10 2 0.2 0
AZIN2_ENST00000294517 AZIN2 Q96A70 Antizyme inhibitor 2 chr1 GO:0030234 Not Cancer Driver No 51 0.111 14 0 0.0 0
B3GAT3 B3GAT3 O94766 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 chr11 GO:0030234 Not Cancer Driver No 42 0.125 139 17 0.122 2
BAD_ENST00000309032 BAD Q92934 Bcl2-associated agonist of cell death chr11 GO:0030234 Not Cancer Driver No 14 0.083 163 14 0.086 0
BCAS3_ENST00000390652 BCAS3 Q9H6U6 BCAS3 microtubule associated cell migration factor chr17 GO:0030234 Not Cancer Driver No 134 0.144 417 67 0.161 0
BCL2L13_ENST00000317582 BCL2L13 Q9BXK5 Bcl-2-like protein 13 chr22 GO:0030234 Not Cancer Driver No 49 0.101 291 30 0.103 0
BEX3_ENST00000372635 BEX3 Q00994 Protein BEX3 chrX GO:0030234 Not Cancer Driver No 19 0.171 98 17 0.173 0
BIN1 BIN1 O00499 Myc box-dependent-interacting protein 1 chr2 GO:0030234 Not Cancer Driver No 65 0.11 456 42 0.092 5
BIRC2 BIRC2 Q13490 Baculoviral IAP repeat-containing protein 2 chr11 GO:0030234 Not Cancer Driver No 69 0.112 83 9 0.108 0
BIRC3_ENST00000532808 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 GO:0030234 Census, Compendium Yes 77 0.127 98 16 0.163 0
BIRC5_ENST00000350051 BIRC5 O15392 Baculoviral IAP repeat-containing protein 5 chr17 GO:0030234 Not Cancer Driver No 20 0.141 49 6 0.122 0
BIRC7 BIRC7 Q96CA5 Baculoviral IAP repeat-containing protein 7 chr20 GO:0030234 Not Cancer Driver No 52 0.174 136 22 0.162 0
BIRC8 BIRC8 Q96P09 Baculoviral IAP repeat-containing protein 8 chr19 GO:0030234 Not Cancer Driver No 79 0.335 39 10 0.256 0
BMP2 BMP2 P12643 Bone morphogenetic protein 2 chr20 GO:0030234 Not Cancer Driver No 73 0.184 139 26 0.187 0
BMPR1A BMPR1A P36894 Bone morphogenetic protein receptor type-1A chr10 GO:0030234 Census, Compendium Yes 66 0.124 21 0 0.0 8
BMPR1B_ENST00000394931 BMPR1B O00238 Bone morphogenetic protein receptor type-1B chr4 GO:0030234 Not Cancer Driver No 84 0.167 64 12 0.188 5
BMPR2 BMPR2 Q13873 Bone morphogenetic protein receptor type-2 chr2 GO:0030234 Compendium Yes 141 0.136 601 70 0.116 19
BRCC3 BRCC3 P46736 Lys-63-specific deubiquitinase BRCC36 chrX GO:0030234 Not Cancer Driver No 39 0.123 74 7 0.095 0
BRPF1_ENST00000457855 BRPF1 P55201 Peregrin chr3 GO:0030234 Not Cancer Driver No 148 0.122 753 95 0.126 2
BST2 BST2 Q10589 Bone marrow stromal antigen 2 chr19 GO:0030234 Not Cancer Driver No 19 0.106 20 0 0.0 0
BTK_ENST00000308731 BTK Q06187 Tyrosine-protein kinase BTK chrX GO:0030234 Census, Compendium Yes 147 0.223 114 27 0.237 110
BTRC BTRC Q9Y297 F-box/WD repeat-containing protein 1A chr10 GO:0030234 Not Cancer Driver No 80 0.132 45 4 0.089 0
CALM1 CALM1 P0DP23 Calmodulin-1 chr14 GO:0030234 Not Cancer Driver No 19 0.128 115 15 0.13 7
CALM2 CALM2 P0DP24 Calmodulin-2 chr2 GO:0030234 Not Cancer Driver No 18 0.121 115 13 0.113 8
CALM3_ENST00000596362 CALM3 P0DP25 Calmodulin-3 chr19 GO:0030234 Not Cancer Driver No 17 0.114 115 10 0.087 3
CALML3 CALML3 P27482 Calmodulin-like protein 3 chr10 GO:0030234 Not Cancer Driver No 34 0.228 105 28 0.267 0
CALML4 CALML4 Q96GE6 Calmodulin-like protein 4 chr15 GO:0030234 Not Cancer Driver No 21 0.107 81 4 0.049 0
CALML5 CALML5 Q9NZT1 Calmodulin-like protein 5 chr10 GO:0030234 Not Cancer Driver No 34 0.233 98 21 0.214 0
CALML6 CALML6 Q8TD86 Calmodulin-like protein 6 chr1 GO:0030234 Not Cancer Driver No 23 0.127 51 4 0.078 0
CAMK2N1 CAMK2N1 Q7Z7J9 Calcium/calmodulin-dependent protein kinase II inhibitor 1 chr1 GO:0030234 Not Cancer Driver No 10 0.128 72 9 0.125 0
CAMK2N2 CAMK2N2 Q96S95 Calcium/calmodulin-dependent protein kinase II inhibitor 2 chr3 GO:0030234 Not Cancer Driver No 6 0.076 74 5 0.068 0
CAPN3 CAPN3 P20807 Calpain-3 chr15 GO:0030234 Not Cancer Driver No 111 0.135 168 11 0.065 52
CARD8_ENST00000519940 CARD8 Q9Y2G2 Caspase recruitment domain-containing protein 8 chr19 GO:0030234 Not Cancer Driver No 53 0.099 126 7 0.056 1
CASP1 CASP1 P29466 Caspase-1 chr11 GO:0030234 Not Cancer Driver No 79 0.196 87 18 0.207 0
CASP3 CASP3 P42574 Caspase-3 chr4 GO:0030234 Census Yes 32 0.116 62 5 0.081 0
CASP8AP2 CASP8AP2 Q9UKL3 CASP8-associated protein 2 chr6 GO:0030234 Not Cancer Driver No 219 0.11 1501 178 0.119 0
CAST_ENST00000395813 CAST P20810 Calpastatin chr5 GO:0030234 Not Cancer Driver No 73 0.103 708 73 0.103 0
CAV1 CAV1 Q03135 Caveolin-1 chr7 GO:0030234 Not Cancer Driver No 30 0.169 2 0 0.0 0
CBX8 CBX8 Q9HC52 Chromobox protein homolog 8 chr17 GO:0030234 Not Cancer Driver No 59 0.152 309 51 0.165 0
CCDC88A_ENST00000642200 CCDC88A Q3V6T2 Girdin chr2 GO:0030234 Not Cancer Driver No 226 0.121 1481 173 0.117 0
CCKBR CCKBR P32239 Gastrin/cholecystokinin type B receptor chr11 GO:0030234 Not Cancer Driver No 122 0.273 61 22 0.361 0
CCL8 CCL8 P80075 C-C motif chemokine 8 chr17 GO:0030234 Not Cancer Driver No 17 0.172 0 0 0.0 0
CCNB1 CCNB1 P14635 G2/mitotic-specific cyclin-B1 chr5 GO:0030234 Not Cancer Driver No 49 0.113 145 14 0.097 0
CCNK CCNK O75909 Cyclin-K chr14 GO:0030234 Not Cancer Driver No 39 0.067 347 15 0.043 1
CCNT1 CCNT1 O60563 Cyclin-T1 chr12 GO:0030234 Not Cancer Driver No 85 0.117 495 61 0.123 0
CCNT2 CCNT2 O60583 Cyclin-T2 chr2 GO:0030234 Not Cancer Driver No 76 0.104 471 52 0.11 0
CCNY CCNY Q8ND76 Cyclin-Y chr10 GO:0030234 Not Cancer Driver No 38 0.111 94 6 0.064 0
CCNYL1 CCNYL1 Q8N7R7 Cyclin-Y-like protein 1 chr2 GO:0030234 Not Cancer Driver No 31 0.086 100 8 0.08 0
CD27 CD27 P26842 CD27 antigen chr12 GO:0030234 Not Cancer Driver No 30 0.115 92 11 0.12 1
CDC20 CDC20 Q12834 Cell division cycle protein 20 homolog chr1 GO:0030234 Not Cancer Driver No 44 0.088 198 15 0.076 0
CDC20B CDC20B Q86Y33 Cell division cycle protein 20 homolog B chr5 GO:0030234 Not Cancer Driver No 99 0.191 152 24 0.158 0
CDC42SE1_ENST00000540998 CDC42SE1 Q9NRR8 CDC42 small effector protein 1 chr1 GO:0030234 Not Cancer Driver No 10 0.127 70 10 0.143 0
CDK5R1 CDK5R1 Q15078 Cyclin-dependent kinase 5 activator 1 chr17 GO:0030234 Not Cancer Driver No 35 0.114 103 16 0.155 0
CDK5R2 CDK5R2 Q13319 Cyclin-dependent kinase 5 activator 2 chr2 GO:0030234 Not Cancer Driver No 14 0.038 204 5 0.025 0
CDKN1A_ENST00000373711 CDKN1A P38936 Cyclin-dependent kinase inhibitor 1 chr6 GO:0030234 Census, Compendium Yes 48 0.293 121 30 0.248 0
CDKN1B CDKN1B P46527 Cyclin-dependent kinase inhibitor 1B chr12 GO:0030234 Census, Compendium Yes 19 0.096 198 19 0.096 0
CDKN1C CDKN1C P49918 Cyclin-dependent kinase inhibitor 1C chr11 GO:0030234 Not Cancer Driver No 2 0.006 256 1 0.004 7
CDKN2A_ENST00000304494 CDKN2A P42771 Cyclin-dependent kinase inhibitor 2A chr9 GO:0030234 Census, Compendium Yes 166 1.064 83 88 1.06 36
CDKN2B CDKN2B P42772 Cyclin-dependent kinase 4 inhibitor B chr9 GO:0030234 Not Cancer Driver No 15 0.109 67 3 0.045 0
CDKN2C_ENST00000371761 CDKN2C P42773 Cyclin-dependent kinase 4 inhibitor C chr1 GO:0030234 Census, Compendium Yes 23 0.137 49 6 0.122 0
CDKN2D_ENST00000335766 CDKN2D P55273 Cyclin-dependent kinase 4 inhibitor D chr19 GO:0030234 Not Cancer Driver No 17 0.102 44 3 0.068 0
CHM CHM P24386 Rab proteins geranylgeranyltransferase component A 1 chrX GO:0030234 Not Cancer Driver No 113 0.173 179 40 0.223 3
CHML CHML P26374 Rab proteins geranylgeranyltransferase component A 2 chr1 GO:0030234 Not Cancer Driver No 91 0.139 197 25 0.127 0
CIB1_ENST00000328649 CIB1 Q99828 Calcium and integrin-binding protein 1 chr15 GO:0030234 Not Cancer Driver No 24 0.126 6 1 0.167 0
CISH_ENST00000348721 CISH Q9NSE2 Cytokine-inducible SH2-containing protein chr3 GO:0030234 Not Cancer Driver No 33 0.128 97 8 0.082 0
CIT_ENST00000261833 CIT O14578 Citron Rho-interacting kinase chr12 GO:0030234 Not Cancer Driver No 284 0.14 1017 160 0.157 3
CKS1B CKS1B P61024 Cyclin-dependent kinases regulatory subunit 1 chr1 GO:0030234 Not Cancer Driver No 10 0.127 10 0 0.0 0
CKS2 CKS2 P33552 Cyclin-dependent kinases regulatory subunit 2 chr9 GO:0030234 Not Cancer Driver No 9 0.114 10 2 0.2 0
CLPX CLPX O76031 ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial chr15 GO:0030234 Not Cancer Driver No 66 0.104 195 22 0.113 1
COL4A3 COL4A3 Q01955 Collagen alpha-3(IV) chain chr2 GO:0030234 Not Cancer Driver No 310 0.186 1433 277 0.193 13
COX6A1 COX6A1 P12074 Cytochrome c oxidase subunit 6A1, mitochondrial chr12 GO:0030234 Not Cancer Driver No 17 0.156 48 5 0.104 0
COX6A2 COX6A2 Q02221 Cytochrome c oxidase subunit 6A2, mitochondrial chr16 GO:0030234 Not Cancer Driver No 14 0.144 42 8 0.19 2
CPEB2_ENST00000507071 CPEB2 Q7Z5Q1 Cytoplasmic polyadenylation element-binding protein 2 chr4 GO:0030234 Not Cancer Driver No 66 0.112 269 17 0.063 0
CPN2_ENST00000429275 CPN2 P22792 Carboxypeptidase N subunit 2 chr3 GO:0030234 Not Cancer Driver No 91 0.167 2 3 1.5 0
CRB2 CRB2 Q5IJ48 Protein crumbs homolog 2 chr9 GO:0030234 Not Cancer Driver No 155 0.121 72 0 0.0 5
CTSC CTSC P53634 Dipeptidyl peptidase 1 chr11 GO:0030234 Not Cancer Driver No 64 0.138 19 5 0.263 29
CTSH CTSH P09668 Pro-cathepsin H chr15 GO:0030234 Not Cancer Driver No 45 0.134 4 0 0.0 0
CWF19L1 CWF19L1 Q69YN2 CWF19-like protein 1 chr10 GO:0030234 Not Cancer Driver No 59 0.11 69 9 0.13 0
CXCL10 CXCL10 P02778 C-X-C motif chemokine 10 chr4 GO:0030234 Not Cancer Driver No 19 0.194 12 4 0.333 0
DFFA DFFA O00273 DNA fragmentation factor subunit alpha chr1 GO:0030234 Not Cancer Driver No 47 0.142 113 18 0.159 0
DGKQ DGKQ P52824 Diacylglycerol kinase theta chr4 GO:0030234 Not Cancer Driver No 56 0.059 264 11 0.042 0
DMPK_ENST00000291270 DMPK Q09013 Myotonin-protein kinase chr19 GO:0030234 Not Cancer Driver No 54 0.086 220 14 0.064 0
DPEP1 DPEP1 P16444 Dipeptidase 1 chr16 GO:0030234 Not Cancer Driver No 54 0.131 41 6 0.146 0
DPM2 DPM2 O94777 Dolichol phosphate-mannose biosynthesis regulatory protein chr9 GO:0030234 Not Cancer Driver No 9 0.107 0 0 0.0 1
EBAG9_ENST00000620557 EBAG9 O00559 Receptor-binding cancer antigen expressed on SiSo cells chr8 GO:0030234 Not Cancer Driver No 35 0.164 173 29 0.168 0
EFNA5 EFNA5 P52803 Ephrin-A5 chr5 GO:0030234 Not Cancer Driver No 34 0.149 25 6 0.24 0
EGF EGF P01133 Pro-epidermal growth factor chr4 GO:0030234 Not Cancer Driver No 184 0.152 191 25 0.131 1
EGFR EGFR P00533 Epidermal growth factor receptor chr7 GO:0030234 Census, Compendium Yes 444 0.367 223 35 0.157 1
EID1 EID1 Q9Y6B2 EP300-interacting inhibitor of differentiation 1 chr15 GO:0030234 Not Cancer Driver No 22 0.118 159 17 0.107 0
EIF5_ENST00000392715 EIF5 P55010 Eukaryotic translation initiation factor 5 chr14 GO:0030234 Not Cancer Driver No 64 0.148 185 23 0.124 0
ELP3 ELP3 Q9H9T3 Elongator complex protein 3 chr8 GO:0030234 Not Cancer Driver No 60 0.11 19 4 0.211 0
ELP4_ENST00000640961 ELP4 Q96EB1 Elongator complex protein 4 chr11 GO:0030234 Not Cancer Driver No 60 0.142 55 4 0.073 0
ERBB3 ERBB3 P21860 Receptor tyrosine-protein kinase erbB-3 chr12 GO:0030234 Census, Compendium Yes 298 0.222 396 70 0.177 3
ERCC4 ERCC4 Q92889 DNA repair endonuclease XPF chr16 GO:0030234 Census Yes 120 0.131 225 27 0.12 15
ERCC6 ERCC6 Q03468 DNA excision repair protein ERCC-6 chr10 GO:0030234 Not Cancer Driver No 211 0.141 829 117 0.141 9
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 GO:0030234 Census, Compendium Yes 121 0.203 195 27 0.138 2
FAF2 FAF2 Q96CS3 FAS-associated factor 2 chr5 GO:0030234 Not Cancer Driver No 54 0.121 171 16 0.094 0
FAM122B_ENST00000370790 PABIR2 Q7Z309 PABIR family member 2 chrX GO:0030234 Not Cancer Driver No 27 0.109 224 25 0.112 0
FAM122C PABIR3 Q6P4D5 PABIR family member 1 chrX GO:0030234 Not Cancer Driver No 35 0.179 26 6 0.231 0
FBLN1 FBLN1 P23142 Fibulin-1 chr22 GO:0030234 Compendium Yes 122 0.174 22 3 0.136 0
FBXO5 FBXO5 Q9UKT4 F-box only protein 5 chr6 GO:0030234 Not Cancer Driver No 48 0.107 113 13 0.115 0
FBXW7_ENST00000603841 FBXW7 Q969H0 F-box/WD repeat-containing protein 7 chr4 GO:0030234 Census, Compendium Yes 322 0.455 230 38 0.165 0
FETUB_ENST00000450521 FETUB Q9UGM5 Fetuin-B chr3 GO:0030234 Not Cancer Driver No 76 0.199 119 30 0.252 0
FGFR1OP CEP43 O95684 Centrosomal protein 43 chr6 GO:0030234 Not Cancer Driver No 43 0.108 272 33 0.121 0
FN1 FN1 P02751 Fibronectin chr2 GO:0030234 Compendium Yes 394 0.159 1243 185 0.149 8
FOXL2 FOXL2 P58012 Forkhead box protein L2 chr3 GO:0030234 Census, Compendium Yes 39 0.104 257 20 0.078 26
FRS2 FRS2 Q8WU20 Fibroblast growth factor receptor substrate 2 chr12 GO:0030234 Not Cancer Driver No 69 0.136 415 58 0.14 0
FYN FYN P06241 Tyrosine-protein kinase Fyn chr6 GO:0030234 Not Cancer Driver No 92 0.171 70 13 0.186 0
FZR1 FZR1 Q9UM11 Fizzy-related protein homolog chr19 GO:0030234 Not Cancer Driver No 74 0.149 184 30 0.163 0
GAPDH GAPDH P04406 Glyceraldehyde-3-phosphate dehydrogenase chr12 GO:0030234 Not Cancer Driver No 39 0.116 24 3 0.125 0
GAS6 GAS6 Q14393 Growth arrest-specific protein 6 chr13 GO:0030234 Not Cancer Driver No 82 0.121 42 6 0.143 0
GCLM GCLM P48507 Glutamate--cysteine ligase regulatory subunit chr1 GO:0030234 Not Cancer Driver No 32 0.117 31 3 0.097 0
GDI1 GDI1 P31150 Rab GDP dissociation inhibitor alpha chrX GO:0030234 Not Cancer Driver No 69 0.154 34 6 0.176 2
GDI2 GDI2 P50395 Rab GDP dissociation inhibitor beta chr10 GO:0030234 Not Cancer Driver No 49 0.11 23 2 0.087 0
GHRL_ENST00000457360 GHRL Q9UBU3 Appetite-regulating hormone chr3 GO:0030234 Not Cancer Driver No 20 0.171 52 11 0.212 0
GLMN GLMN Q92990 Glomulin chr1 GO:0030234 Not Cancer Driver No 49 0.082 37 6 0.162 0
GM2A GM2A P17900 Ganglioside GM2 activator chr5 GO:0030234 Not Cancer Driver No 26 0.135 0 0 0.0 2
GPC3_ENST00000370818 GPC3 P51654 Glypican-3 chrX GO:0030234 Census Yes 89 0.153 86 11 0.128 1
GPS1_ENST00000306823 GPS1 Q13098 COP9 signalosome complex subunit 1 chr17 GO:0030234 Not Cancer Driver No 62 0.126 106 14 0.132 0
GPS2 GPS2 Q13227 G protein pathway suppressor 2 chr17 GO:0030234 Not Cancer Driver No 29 0.089 319 26 0.082 0
GPSM1 GPSM1 Q86YR5 G-protein-signaling modulator 1 chr9 GO:0030234 Not Cancer Driver No 68 0.101 344 35 0.102 0
GPSM2_ENST00000642355 GPSM2 P81274 G-protein-signaling modulator 2 chr1 GO:0030234 Not Cancer Driver No 79 0.115 240 21 0.087 0
GREM1 GREM1 O60565 Gremlin-1 chr15 GO:0030234 Not Cancer Driver No 25 0.136 77 12 0.156 0
GRM5 GRM5 P41594 Metabotropic glutamate receptor 5 chr11 GO:0030234 Not Cancer Driver No 312 0.257 323 51 0.158 0
GRM7 GRM7 Q14831 Metabotropic glutamate receptor 7 chr3 GO:0030234 Not Cancer Driver No 316 0.345 91 31 0.341 1
GTF2F1 GTF2F1 P35269 General transcription factor IIF subunit 1 chr19 GO:0030234 Not Cancer Driver No 63 0.122 426 48 0.113 0
GUCA1A GUCA1A P43080 Guanylyl cyclase-activating protein 1 chr6 GO:0030234 Not Cancer Driver No 39 0.194 20 4 0.2 17
GUCA1B GUCA1B Q9UMX6 Guanylyl cyclase-activating protein 2 chr6 GO:0030234 Not Cancer Driver No 26 0.13 2 0 0.0 1
GUCA1C GUCA1C O95843 Guanylyl cyclase-activating protein 3 chr3 GO:0030234 Not Cancer Driver No 60 0.287 35 6 0.171 0
GUCA2A GUCA2A Q02747 Guanylin chr1 GO:0030234 Not Cancer Driver No 15 0.13 18 1 0.056 0
GUCA2B GUCA2B Q16661 Guanylate cyclase activator 2B chr1 GO:0030234 Not Cancer Driver No 17 0.152 0 0 0.0 0
H2AFY MACROH2A1 O75367 Core histone macro-H2A.1 chr5 GO:0030234 Not Cancer Driver No 46 0.124 125 19 0.152 0
HEXIM1 HEXIM1 O94992 Protein HEXIM1 chr17 GO:0030234 Not Cancer Driver No 40 0.111 352 40 0.114 0
HEXIM2_ENST00000592695 HEXIM2 Q96MH2 Protein HEXIM2 chr17 GO:0030234 Not Cancer Driver No 35 0.122 286 35 0.122 0
HSP90AA1_ENST00000216281 HSP90AA1 P07900 Heat shock protein HSP 90-alpha chr14 GO:0030234 Census, Compendium Yes 106 0.145 257 37 0.144 0
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 GO:0030234 Census, Compendium Yes 100 0.138 254 43 0.169 0
HSPB1 HSPB1 P04792 Heat shock protein beta-1 chr7 GO:0030234 Not Cancer Driver No 10 0.049 118 8 0.068 20
HYAL2_ENST00000357750 HYAL2 Q12891 Hyaluronidase-2 chr3 GO:0030234 Not Cancer Driver No 52 0.11 8 1 0.125 0
IBTK IBTK Q9P2D0 Inhibitor of Bruton tyrosine kinase chr6 GO:0030234 Not Cancer Driver No 146 0.108 364 39 0.107 0
IGFBP3_ENST00000275521 IGFBP3 P17936 Insulin-like growth factor-binding protein 3 chr7 GO:0030234 Not Cancer Driver No 41 0.141 103 25 0.243 0
IKBKE IKBKE Q14164 Inhibitor of nuclear factor kappa-B kinase subunit epsilon chr1 GO:0030234 Not Cancer Driver No 108 0.151 76 13 0.171 0
INCA1_ENST00000576820 INCA1 Q0VD86 Protein INCA1 chr17 GO:0030234 Not Cancer Driver No 18 0.076 195 14 0.072 0
INKA1 INKA1 Q96EL1 PAK4-inhibitor INKA1 chr3 GO:0030234 Not Cancer Driver No 40 0.139 227 36 0.159 0
INKA2 INKA2 Q9NTI7 PAK4-inhibitor INKA2 chr1 GO:0030234 Not Cancer Driver No 41 0.138 271 38 0.14 0
IPO5_ENST00000490680 IPO5 O00410 Importin-5 chr13 GO:0030234 Not Cancer Driver No 128 0.117 52 3 0.058 0
IQGAP1 IQGAP1 P46940 Ras GTPase-activating-like protein IQGAP1 chr15 GO:0030234 Not Cancer Driver No 183 0.11 351 35 0.1 0
IQGAP2 IQGAP2 Q13576 Ras GTPase-activating-like protein IQGAP2 chr5 GO:0030234 Not Cancer Driver No 237 0.15 255 50 0.196 0
IRAK1 IRAK1 P51617 Interleukin-1 receptor-associated kinase 1 chrX GO:0030234 Compendium Yes 71 0.1 337 39 0.116 0
ITGB1BP1_ENST00000355346 ITGB1BP1 O14713 Integrin beta-1-binding protein 1 chr2 GO:0030234 Not Cancer Driver No 26 0.13 58 11 0.19 0
KAT2B KAT2B Q92831 Histone acetyltransferase KAT2B chr3 GO:0030234 Not Cancer Driver No 107 0.129 266 27 0.102 0
LCK LCK P06239 Tyrosine-protein kinase Lck chr1 GO:0030234 Census Yes 86 0.169 94 13 0.138 1
LILRB4 LILRB4 Q8NHJ6 Leukocyte immunoglobulin-like receptor subfamily B member 4 chr19 GO:0030234 Not Cancer Driver No 162 0.362 277 115 0.415 0
LRP6 LRP6 O75581 Low-density lipoprotein receptor-related protein 6 chr12 GO:0030234 Not Cancer Driver No 206 0.128 255 30 0.118 5
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 GO:0030234 Not Cancer Driver No 519 0.205 90 17 0.189 23
LXN LXN Q9BS40 Latexin chr3 GO:0030234 Not Cancer Driver No 21 0.095 91 9 0.099 0
MAL MAL P21145 Myelin and lymphocyte protein chr2 GO:0030234 Not Cancer Driver No 21 0.137 0 0 0.0 0
MAP2K6 MAP2K6 P52564 Dual specificity mitogen-activated protein kinase kinase 6 chr17 GO:0030234 Not Cancer Driver No 48 0.144 55 11 0.2 0
MAP3K14 MAP3K14 Q99558 Mitogen-activated protein kinase kinase kinase 14 chr17 GO:0030234 Not Cancer Driver No 94 0.099 543 52 0.096 0
MAPK8_ENST00000374189 MAPK8 P45983 Mitogen-activated protein kinase 8 chr10 GO:0030234 Not Cancer Driver No 64 0.15 94 9 0.096 0
MAT2B MAT2B Q9NZL9 Methionine adenosyltransferase 2 subunit beta chr5 GO:0030234 Not Cancer Driver No 42 0.126 59 8 0.136 0
MNAT1 MNAT1 P51948 CDK-activating kinase assembly factor MAT1 chr14 GO:0030234 Not Cancer Driver No 23 0.074 64 2 0.031 0
MT3 MT3 P25713 Metallothionein-3 chr16 GO:0030234 Not Cancer Driver No 7 0.103 0 0 0.0 0
MTMR9 MTMR9 Q96QG7 Myotubularin-related protein 9 chr8 GO:0030234 Not Cancer Driver No 60 0.109 45 7 0.156 0
MYOZ1 MYOZ1 Q9NP98 Myozenin-1 chr10 GO:0030234 Not Cancer Driver No 49 0.164 223 39 0.175 0
NAIP_ENST00000194097 NAIP Q13075 Baculoviral IAP repeat-containing protein 1 chr5 GO:0030234 Not Cancer Driver No 39 0.028 67 4 0.06 0
NCAPG2_ENST00000356309 NCAPG2 Q86XI2 Condensin-2 complex subunit G2 chr7 GO:0030234 Not Cancer Driver No 113 0.099 72 8 0.111 3
NCF1 NCF1 P14598 Neutrophil cytosol factor 1 chr7 GO:0030234 Not Cancer Driver No 37 0.095 181 12 0.066 1
NCF2 NCF2 P19878 Neutrophil cytosol factor 2 chr1 GO:0030234 Not Cancer Driver No 97 0.184 183 34 0.186 14
NCF4_ENST00000248899 NCF4 Q15080 Neutrophil cytosol factor 4 chr22 GO:0030234 Not Cancer Driver No 60 0.177 27 4 0.148 1
NCS1 NCS1 P62166 Neuronal calcium sensor 1 chr9 GO:0030234 Not Cancer Driver No 25 0.132 26 2 0.077 0
NGF NGF P01138 Beta-nerve growth factor chr1 GO:0030234 Not Cancer Driver No 66 0.274 93 25 0.269 1
NKX3-1 NKX3-1 Q99801 Homeobox protein Nkx-3.1 chr8 GO:0030234 Not Cancer Driver No 35 0.15 171 16 0.094 0
NLRC4_ENST00000360906 NLRC4 Q9NPP4 NLR family CARD domain-containing protein 4 chr2 GO:0030234 Not Cancer Driver No 205 0.2 15 2 0.133 3
NLRP12_ENST00000324134 NLRP12 P59046 NACHT, LRR and PYD domains-containing protein 12 chr19 GO:0030234 Not Cancer Driver No 310 0.292 116 43 0.371 0
NLRP1_ENST00000572272 NLRP1 Q9C000 NACHT, LRR and PYD domains-containing protein 1 chr17 GO:0030234 Not Cancer Driver No 222 0.151 340 65 0.191 6
NLRP7_ENST00000590030 NLRP7 Q8WX94 NACHT, LRR and PYD domains-containing protein 7 chr19 GO:0030234 Not Cancer Driver No 300 0.306 71 20 0.282 9
NOD1 NOD1 Q9Y239 Nucleotide-binding oligomerization domain-containing protein 1 chr7 GO:0030234 Not Cancer Driver No 130 0.136 38 7 0.184 0
NOL3_ENST00000268605 NOL3 O60936 Nucleolar protein 3 chr16 GO:0030234 Not Cancer Driver No 20 0.096 179 17 0.095 2
NOXA1 NOXA1 Q86UR1 NADPH oxidase activator 1 chr9 GO:0030234 Not Cancer Driver No 27 0.057 215 14 0.065 0
NOXO1 NOXO1 Q8NFA2 NADPH oxidase organizer 1 chr16 GO:0030234 Not Cancer Driver No 29 0.077 182 9 0.049 0
NRG1_ENST00000405005 NRG1 Q02297 Pro-neuregulin-1, membrane-bound isoform chr8 GO:0030234 Census, Compendium Yes 159 0.248 528 132 0.25 0
NRG3_ENST00000404547 NRG3 P56975 Pro-neuregulin-3, membrane-bound isoform chr10 GO:0030234 Not Cancer Driver No 227 0.315 425 134 0.315 0
NSMAF_ENST00000038176 NSMAF Q92636 Protein FAN chr8 GO:0030234 Not Cancer Driver No 118 0.129 80 13 0.163 0
NUPR1_ENST00000324873 NUPR1 O60356 Nuclear protein 1 chr16 GO:0030234 Not Cancer Driver No 10 0.122 82 10 0.122 0
OAZ1 OAZ1 P54368 Ornithine decarboxylase antizyme 1 chr19 GO:0030234 Not Cancer Driver No 30 0.132 109 12 0.11 0
OAZ2 OAZ2 O95190 Ornithine decarboxylase antizyme 2 chr15 GO:0030234 Not Cancer Driver No 15 0.079 11 0 0.0 0
OAZ3_ENST00000639906 OAZ3 Q9UMX2 Ornithine decarboxylase antizyme 3 chr1 GO:0030234 Not Cancer Driver No 37 0.157 33 2 0.061 0
PAK2 PAK2 Q13177 Serine/threonine-protein kinase PAK 2 chr3 GO:0030234 Compendium Yes 89 0.17 242 49 0.202 0
PARK7_ENST00000377488 PARK7 Q99497 Parkinson disease protein 7 chr1 GO:0030234 Not Cancer Driver No 11 0.058 30 0 0.0 5
PCNA PCNA P12004 Proliferating cell nuclear antigen chr20 GO:0030234 Not Cancer Driver No 30 0.115 22 3 0.136 1
PCOLCE PCOLCE Q15113 Procollagen C-endopeptidase enhancer 1 chr7 GO:0030234 Not Cancer Driver No 46 0.102 187 18 0.096 0
PCOLCE2 PCOLCE2 Q9UKZ9 Procollagen C-endopeptidase enhancer 2 chr3 GO:0030234 Not Cancer Driver No 102 0.246 25 3 0.12 0
PDC PDC P20941 Phosducin chr1 GO:0030234 Not Cancer Driver No 26 0.106 91 14 0.154 0
PDCD5 PDCD5 O14737 Programmed cell death protein 5 chr19 GO:0030234 Not Cancer Driver No 15 0.12 91 7 0.077 0
PDE6D PDE6D O43924 Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta chr2 GO:0030234 Not Cancer Driver No 23 0.153 1 0 0.0 0
PDGFB PDGFB P01127 Platelet-derived growth factor subunit B chr22 GO:0030234 Census Yes 37 0.154 99 22 0.222 2
PDPK1 PDPK1 O15530 3-phosphoinositide-dependent protein kinase 1 chr16 GO:0030234 Not Cancer Driver No 33 0.059 121 12 0.099 0
PDZD3_ENST00000531114 PDZD3 Q86UT5 Na(+)/H(+) exchange regulatory cofactor NHE-RF4 chr11 GO:0030234 Not Cancer Driver No 58 0.102 199 19 0.095 0
PHACTR4_ENST00000373839 PHACTR4 Q8IZ21 Phosphatase and actin regulator 4 chr1 GO:0030234 Not Cancer Driver No 80 0.114 679 76 0.112 0
PIF1_ENST00000559239 PIF1 Q9H611 ATP-dependent DNA helicase PIF1 chr15 GO:0030234 Not Cancer Driver No 54 0.084 209 11 0.053 0
PIK3R1 PIK3R1 P27986 Phosphatidylinositol 3-kinase regulatory subunit alpha chr5 GO:0030234 Census, Compendium Yes 154 0.213 268 61 0.228 2
PIK3R2_ENST00000617130 PIK3R2 O00459 Phosphatidylinositol 3-kinase regulatory subunit beta chr19 GO:0030234 Not Cancer Driver No 96 0.132 418 47 0.112 3
PIK3R3_ENST00000372006 PIK3R3 Q92569 Phosphatidylinositol 3-kinase regulatory subunit gamma chr1 GO:0030234 Not Cancer Driver No 51 0.111 149 20 0.134 0
PIK3R5 PIK3R5 Q8WYR1 Phosphoinositide 3-kinase regulatory subunit 5 chr17 GO:0030234 Not Cancer Driver No 143 0.163 316 55 0.174 1
PIK3R6_ENST00000614407 PIK3R6 Q5UE93 Phosphoinositide 3-kinase regulatory subunit 6 chr17 GO:0030234 Not Cancer Driver No 100 0.133 156 26 0.167 0
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 GO:0030234 Not Cancer Driver No 57 0.098 99 13 0.131 23
PINLYP_ENST00000599207 PINLYP A6NC86 phospholipase A2 inhibitor and Ly6/PLAUR domain-containing protein chr19 GO:0030234 Not Cancer Driver No 1 0.005 0 0 0.0 0
PINX1 PINX1 Q96BK5 PIN2/TERF1-interacting telomerase inhibitor 1 chr8 GO:0030234 Not Cancer Driver No 66 0.201 328 66 0.201 0
PKIA PKIA P61925 cAMP-dependent protein kinase inhibitor alpha chr8 GO:0030234 Not Cancer Driver No 18 0.237 76 18 0.237 0
PKIB_ENST00000368448 PKIB Q9C010 cAMP-dependent protein kinase inhibitor beta chr6 GO:0030234 Not Cancer Driver No 13 0.167 78 13 0.167 0
PKIG_ENST00000372891 PKIG Q9Y2B9 cAMP-dependent protein kinase inhibitor gamma chr20 GO:0030234 Not Cancer Driver No 15 0.197 76 15 0.197 0
PLAA PLAA Q9Y263 Phospholipase A-2-activating protein chr9 GO:0030234 Not Cancer Driver No 78 0.098 150 14 0.093 2
POLG2 POLG2 Q9UHN1 DNA polymerase subunit gamma-2, mitochondrial chr17 GO:0030234 Not Cancer Driver No 64 0.132 46 4 0.087 3
POT1 POT1 Q9NUX5 Protection of telomeres protein 1 chr7 GO:0030234 Census, Compendium Yes 113 0.178 31 6 0.194 9
PPP1R11 PPP1R11 O60927 E3 ubiquitin-protein ligase PPP1R11 chr6 GO:0030234 Not Cancer Driver No 17 0.135 126 17 0.135 0
PPP1R14A PPP1R14A Q96A00 Protein phosphatase 1 regulatory subunit 14A chr19 GO:0030234 Not Cancer Driver No 14 0.095 113 10 0.088 0
PPP1R14B PPP1R14B Q96C90 Protein phosphatase 1 regulatory subunit 14B chr11 GO:0030234 Not Cancer Driver No 10 0.068 94 8 0.085 0
PPP1R14C PPP1R14C Q8TAE6 Protein phosphatase 1 regulatory subunit 14C chr6 GO:0030234 Not Cancer Driver No 14 0.085 125 9 0.072 0
PPP1R14D_ENST00000299174 PPP1R14D Q9NXH3 Protein phosphatase 1 regulatory subunit 14D chr15 GO:0030234 Not Cancer Driver No 10 0.069 119 10 0.084 0
PPP1R15A PPP1R15A O75807 Protein phosphatase 1 regulatory subunit 15A chr19 GO:0030234 Not Cancer Driver No 83 0.123 628 72 0.115 0
PPP1R16A_ENST00000435887 PPP1R16A Q96I34 Protein phosphatase 1 regulatory subunit 16A chr8 GO:0030234 Not Cancer Driver No 56 0.106 308 26 0.084 0
PPP1R16B PPP1R16B Q96T49 Protein phosphatase 1 regulatory inhibitor subunit 16B chr20 GO:0030234 Not Cancer Driver No 132 0.233 220 66 0.3 0
PPP1R17 PPP1R17 O96001 Protein phosphatase 1 regulatory subunit 17 chr7 GO:0030234 Not Cancer Driver No 39 0.252 143 36 0.252 0
PPP1R1A PPP1R1A Q13522 Protein phosphatase 1 regulatory subunit 1A chr12 GO:0030234 Not Cancer Driver No 24 0.14 171 24 0.14 0
PPP1R1B PPP1R1B Q9UD71 Protein phosphatase 1 regulatory subunit 1B chr17 GO:0030234 Not Cancer Driver No 30 0.147 204 30 0.147 0
PPP1R2 PPP1R2 P41236 Protein phosphatase inhibitor 2 chr3 GO:0030234 Not Cancer Driver No 19 0.093 205 19 0.093 0
PPP1R7 PPP1R7 Q15435 Protein phosphatase 1 regulatory subunit 7 chr2 GO:0030234 Not Cancer Driver No 46 0.128 78 16 0.205 0
PPP1R8 PPP1R8 Q12972 Nuclear inhibitor of protein phosphatase 1 chr1 GO:0030234 Not Cancer Driver No 24 0.068 251 19 0.076 0
PPP2R5A PPP2R5A Q15172 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform chr1 GO:0030234 Not Cancer Driver No 55 0.113 93 5 0.054 0
PPP2R5B PPP2R5B Q15173 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform chr11 GO:0030234 Not Cancer Driver No 79 0.159 119 9 0.076 0
PPP2R5C_ENST00000334743 PPP2R5C Q13362 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform chr14 GO:0030234 Not Cancer Driver No 65 0.124 89 16 0.18 0
PPP2R5D PPP2R5D Q14738 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform chr6 GO:0030234 Not Cancer Driver No 64 0.106 178 13 0.073 4
PPP2R5E PPP2R5E Q16537 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform chr14 GO:0030234 Not Cancer Driver No 68 0.146 86 20 0.233 0
PPP3R1 PPP3R1 P63098 Calcineurin subunit B type 1 chr2 GO:0030234 Not Cancer Driver No 19 0.112 1 0 0.0 0
PPP3R2 PPP3R2 Q96LZ3 Calcineurin subunit B type 2 chr9 GO:0030234 Not Cancer Driver No 61 0.359 12 5 0.417 0
PPP4C_ENST00000561610 PPP4C P60510 Serine/threonine-protein phosphatase 4 catalytic subunit chr16 GO:0030234 Not Cancer Driver No 41 0.134 0 0 0.0 0
PPP4R3A_ENST00000554943 PPP4R3A Q6IN85 Serine/threonine-protein phosphatase 4 regulatory subunit 3A chr14 GO:0030234 Not Cancer Driver No 89 0.107 255 29 0.114 0
PPP4R3B PPP4R3B Q5MIZ7 Serine/threonine-protein phosphatase 4 regulatory subunit 3B chr2 GO:0030234 Not Cancer Driver No 100 0.118 240 33 0.138 0
PPP4R3C PPP4R3C Q6ZMV5 Protein PPP4R3C chrX GO:0030234 Not Cancer Driver No 1 0.001 184 0 0.0 0
PRDX3 PRDX3 P30048 Thioredoxin-dependent peroxide reductase, mitochondrial chr10 GO:0030234 Not Cancer Driver No 23 0.09 23 3 0.13 0
PRDX5 PRDX5 P30044 Peroxiredoxin-5, mitochondrial chr11 GO:0030234 Not Cancer Driver No 22 0.103 0 0 0.0 0
PRKAG1_ENST00000548065 PRKAG1 P54619 5'-AMP-activated protein kinase subunit gamma-1 chr12 GO:0030234 Not Cancer Driver No 35 0.106 25 2 0.08 0
PRKAG2 PRKAG2 Q9UGJ0 5'-AMP-activated protein kinase subunit gamma-2 chr7 GO:0030234 Not Cancer Driver No 76 0.134 240 45 0.188 7
PRKAR1A_ENST00000536854 PRKAR1A P10644 cAMP-dependent protein kinase type I-alpha regulatory subunit chr17 GO:0030234 Census, Compendium Yes 39 0.102 66 11 0.167 17
PRKAR1B_ENST00000403562 PRKAR1B P31321 cAMP-dependent protein kinase type I-beta regulatory subunit chr7 GO:0030234 Not Cancer Driver No 53 0.139 71 13 0.183 0
PRKAR2A PRKAR2A P13861 cAMP-dependent protein kinase type II-alpha regulatory subunit chr3 GO:0030234 Not Cancer Driver No 37 0.092 149 13 0.087 0
PRKAR2B PRKAR2B P31323 cAMP-dependent protein kinase type II-beta regulatory subunit chr7 GO:0030234 Not Cancer Driver No 60 0.144 125 4 0.032 0
PRNP PRNP P04156 Major prion protein chr20 GO:0030234 Not Cancer Driver No 36 0.142 115 7 0.061 18
PRSS22 PRSS22 Q9GZN4 Brain-specific serine protease 4 chr16 GO:0030234 Not Cancer Driver No 37 0.117 28 5 0.179 0
PSENEN_ENST00000222266 PSENEN Q9NZ42 Gamma-secretase subunit PEN-2 chr19 GO:0030234 Not Cancer Driver No 17 0.168 0 0 0.0 0
PSMC3IP PSMC3IP Q9P2W1 Homologous-pairing protein 2 homolog chr17 GO:0030234 Not Cancer Driver No 25 0.115 73 8 0.11 0
PSMD1 PSMD1 Q99460 26S proteasome non-ATPase regulatory subunit 1 chr2 GO:0030234 Not Cancer Driver No 110 0.115 201 19 0.095 0
PSMD14 PSMD14 O00487 26S proteasome non-ATPase regulatory subunit 14 chr2 GO:0030234 Not Cancer Driver No 23 0.074 67 6 0.09 0
PSMD2 PSMD2 Q13200 26S proteasome non-ATPase regulatory subunit 2 chr3 GO:0030234 Not Cancer Driver No 100 0.11 135 14 0.104 0
PSMD3 PSMD3 O43242 26S proteasome non-ATPase regulatory subunit 3 chr17 GO:0030234 Not Cancer Driver No 69 0.129 152 19 0.125 0
PSMD6_ENST00000295901 PSMD6 Q15008 26S proteasome non-ATPase regulatory subunit 6 chr3 GO:0030234 Not Cancer Driver No 33 0.085 40 3 0.075 0
PSME1_ENST00000206451 PSME1 Q06323 Proteasome activator complex subunit 1 chr14 GO:0030234 Not Cancer Driver No 20 0.08 80 8 0.1 0
PSME2 PSME2 Q9UL46 Proteasome activator complex subunit 2 chr14 GO:0030234 Not Cancer Driver No 32 0.134 39 3 0.077 0
PSME3_ENST00000590720 PSME3 P61289 Proteasome activator complex subunit 3 chr17 GO:0030234 Not Cancer Driver No 20 0.079 25 5 0.2 0
PSME4 PSME4 Q14997 Proteasome activator complex subunit 4 chr2 GO:0030234 Not Cancer Driver No 214 0.116 134 12 0.09 0
PTPA_ENST00000337738 PTPA Q15257 Serine/threonine-protein phosphatase 2A activator chr9 GO:0030234 Not Cancer Driver No 40 0.112 63 2 0.032 0
PYCARD PYCARD Q9ULZ3 Apoptosis-associated speck-like protein containing a CARD chr16 GO:0030234 Not Cancer Driver No 16 0.082 39 4 0.103 0
PYGO2 PYGO2 Q9BRQ0 Pygopus homolog 2 chr1 GO:0030234 Not Cancer Driver No 51 0.126 340 43 0.126 0
RAB3GAP2 RAB3GAP2 Q9H2M9 Rab3 GTPase-activating protein non-catalytic subunit chr1 GO:0030234 Not Cancer Driver No 168 0.121 143 17 0.119 2
RACK1 RACK1 P63244 Receptor of activated protein C kinase 1 chr5 GO:0030234 Not Cancer Driver No 34 0.107 13 0 0.0 0
RANBP1_ENST00000331821 RANBP1 P43487 Ran-specific GTPase-activating protein chr22 GO:0030234 Not Cancer Driver No 19 0.095 137 16 0.117 0
RARRES1 RARRES1 P49788 Retinoic acid receptor responder protein 1 chr3 GO:0030234 Not Cancer Driver No 24 0.082 79 3 0.038 0
RCAN1_ENST00000313806 RCAN1 P53805 Calcipressin-1 chr21 GO:0030234 Not Cancer Driver No 26 0.103 104 7 0.067 0
RCAN2_ENST00000330430 RCAN2 Q14206 Calcipressin-2 chr6 GO:0030234 Not Cancer Driver No 43 0.218 92 20 0.217 0
RCAN3_ENST00000538532 RCAN3 Q9UKA8 Calcipressin-3 chr1 GO:0030234 Not Cancer Driver No 34 0.141 121 18 0.149 0
RCVRN RCVRN P35243 Recoverin chr17 GO:0030234 Not Cancer Driver No 37 0.185 24 5 0.208 0
RECK RECK O95980 Reversion-inducing cysteine-rich protein with Kazal motifs chr9 GO:0030234 Not Cancer Driver No 115 0.118 9 2 0.222 0
RGN RGN Q15493 Regucalcin chrX GO:0030234 Not Cancer Driver No 38 0.127 14 3 0.214 0
RGS14 RGS14 O43566 Regulator of G-protein signaling 14 chr5 GO:0030234 Not Cancer Driver No 57 0.101 309 37 0.12 0
RGS2 RGS2 P41220 Regulator of G-protein signaling 2 chr1 GO:0030234 Not Cancer Driver No 30 0.142 50 4 0.08 0
RHOH_ENST00000617441 RHOH Q15669 Rho-related GTP-binding protein RhoH chr4 GO:0030234 Census Yes 41 0.215 12 3 0.25 0
RING1 RING1 Q06587 E3 ubiquitin-protein ligase RING1 chr6 GO:0030234 Not Cancer Driver No 60 0.148 302 44 0.146 0
RIPK3 RIPK3 Q9Y572 Receptor-interacting serine/threonine-protein kinase 3 chr14 GO:0030234 Not Cancer Driver No 66 0.127 295 39 0.132 0
RNH1_ENST00000397604 RNH1 P13489 Ribonuclease inhibitor chr11 GO:0030234 Not Cancer Driver No 40 0.087 0 0 0.0 0
ROCK1 ROCK1 Q13464 Rho-associated protein kinase 1 chr18 GO:0030234 Not Cancer Driver No 184 0.136 780 103 0.132 0
RPL11 RPL11 P62913 60S ribosomal protein L11 chr1 GO:0030234 Not Cancer Driver No 27 0.152 12 1 0.083 1
RPL23_ENST00000394332 RPL23 P62829 60S ribosomal protein L23 chr17 GO:0030234 Not Cancer Driver No 14 0.1 29 4 0.138 0
RPL37 RPL37 P61927 60S ribosomal protein L37 chr5 GO:0030234 Not Cancer Driver No 12 0.124 83 10 0.12 0
RPL5_ENST00000370321 RPL5 P46777 60S ribosomal protein L5 chr1 GO:0030234 Census Yes 57 0.192 96 17 0.177 2
RPS15_ENST00000592588 RPS15 P62841 40S ribosomal protein S15 chr19 GO:0030234 Not Cancer Driver No 13 0.09 59 7 0.119 0
RPS20_ENST00000521262 RPS20 P60866 40S ribosomal protein S20 chr8 GO:0030234 Not Cancer Driver No 18 0.151 53 8 0.151 0
RPS27L RPS27L Q71UM5 40S ribosomal protein S27-like chr15 GO:0030234 Not Cancer Driver No 4 0.048 22 2 0.091 0
RPS6KA1_ENST00000374168 RPS6KA1 Q15418 Ribosomal protein S6 kinase alpha-1 chr1 GO:0030234 Not Cancer Driver No 94 0.128 178 32 0.18 0
RPS6KA3_ENST00000379565 RPS6KA3 P51812 Ribosomal protein S6 kinase alpha-3 chrX GO:0030234 Compendium Yes 106 0.143 145 18 0.124 13
RPS7_ENST00000645674 RPS7 P62081 40S ribosomal protein S7 chr2 GO:0030234 Not Cancer Driver No 29 0.149 39 7 0.179 0
RPTOR RPTOR Q8N122 Regulatory-associated protein of mTOR chr17 GO:0030234 Not Cancer Driver No 176 0.132 241 21 0.087 0
RTKN RTKN Q9BST9 Rhotekin chr2 GO:0030234 Not Cancer Driver No 67 0.119 265 35 0.132 0
SCG5 SCG5 P05408 Neuroendocrine protein 7B2 chr15 GO:0030234 Not Cancer Driver No 25 0.118 174 21 0.121 0
SCGB1A1 SCGB1A1 P11684 Uteroglobin chr11 GO:0030234 Not Cancer Driver No 12 0.132 14 2 0.143 0
SERPINB9 SERPINB9 P50453 Serpin B9 chr6 GO:0030234 Not Cancer Driver No 64 0.17 22 2 0.091 0
SESN2 SESN2 P58004 Sestrin-2 chr1 GO:0030234 Not Cancer Driver No 74 0.154 147 26 0.177 0
SFN SFN P31947 14-3-3 protein sigma chr1 GO:0030234 Not Cancer Driver No 27 0.109 75 9 0.12 0
SFRP2 SFRP2 Q96HF1 Secreted frizzled-related protein 2 chr4 GO:0030234 Not Cancer Driver No 47 0.159 1 0 0.0 0
SH3BP4_ENST00000392011 SH3BP4 Q9P0V3 SH3 domain-binding protein 4 chr2 GO:0030234 Not Cancer Driver No 143 0.148 241 43 0.178 0
SH3PXD2A_ENST00000369774 SH3PXD2A Q5TCZ1 SH3 and PX domain-containing protein 2A chr10 GO:0030234 Not Cancer Driver No 141 0.124 797 101 0.127 0
SH3PXD2B SH3PXD2B A1X283 SH3 and PX domain-containing protein 2B chr5 GO:0030234 Not Cancer Driver No 122 0.134 660 101 0.153 1
SKI SKI P12755 Ski oncogene chr1 GO:0030234 Census Yes 44 0.06 432 26 0.06 14
SLA2 SLA2 Q9H6Q3 Src-like-adapter 2 chr20 GO:0030234 Not Cancer Driver No 32 0.123 43 9 0.209 0
SLIT2 SLIT2 O94813 Slit homolog 2 protein chr4 GO:0030234 Not Cancer Driver No 428 0.28 31 13 0.419 0
SNCA_ENST00000506244 SNCA P37840 Alpha-synuclein chr4 GO:0030234 Not Cancer Driver No 21 0.15 107 13 0.121 5
SNCB_ENST00000510387 SNCB Q16143 Beta-synuclein chr5 GO:0030234 Not Cancer Driver No 23 0.172 110 21 0.191 0
SOCS1 SOCS1 O15524 Suppressor of cytokine signaling 1 chr16 GO:0030234 Census, Compendium Yes 22 0.104 66 3 0.045 2
SOCS2_ENST00000536696 SOCS2 O14508 Suppressor of cytokine signaling 2 chr12 GO:0030234 Not Cancer Driver No 32 0.162 61 2 0.033 0
SOCS3 SOCS3 O14543 Suppressor of cytokine signaling 3 chr17 GO:0030234 Not Cancer Driver No 27 0.12 111 14 0.126 0
SOCS4_ENST00000555846 SOCS4 Q8WXH5 Suppressor of cytokine signaling 4 chr14 GO:0030234 Not Cancer Driver No 43 0.098 136 13 0.096 0
SOCS5 SOCS5 O75159 Suppressor of cytokine signaling 5 chr2 GO:0030234 Not Cancer Driver No 84 0.157 297 46 0.155 0
SOCS6_ENST00000582322 SOCS6 O14544 Suppressor of cytokine signaling 6 chr18 GO:0030234 Not Cancer Driver No 81 0.151 299 48 0.161 0
SPOCK1 SPOCK1 Q08629 Testican-1 chr5 GO:0030234 Not Cancer Driver No 82 0.187 107 16 0.15 0
SPOCK2_ENST00000317376 SPOCK2 Q92563 Testican-2 chr10 GO:0030234 Not Cancer Driver No 48 0.113 113 8 0.071 0
SPOCK3_ENST00000511531 SPOCK3 Q9BQ16 Testican-3 chr4 GO:0030234 Not Cancer Driver No 132 0.303 68 38 0.559 0
SPRED1 SPRED1 Q7Z699 Sprouty-related, EVH1 domain-containing protein 1 chr15 GO:0030234 Not Cancer Driver No 71 0.16 194 35 0.18 2
SPRED2 SPRED2 Q7Z698 Sprouty-related, EVH1 domain-containing protein 2 chr2 GO:0030234 Not Cancer Driver No 73 0.175 228 43 0.189 0
SPRY2 SPRY2 O43597 Protein sprouty homolog 2 chr13 GO:0030234 Not Cancer Driver No 46 0.146 169 29 0.172 1
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:0030234 Census Yes 53 0.099 130 11 0.085 1
ST20_ENST00000562759 ST20 Q9HBF5 Suppressor of tumorigenicity 20 protein chr15 GO:0030234 Not Cancer Driver No 17 0.215 0 0 0.0 0
STX4 STX4 Q12846 Syntaxin-4 chr16 GO:0030234 Not Cancer Driver No 50 0.168 152 20 0.132 0
STYX STYX Q8WUJ0 Serine/threonine/tyrosine-interacting protein chr14 GO:0030234 Not Cancer Driver No 20 0.09 30 2 0.067 0
STYXL1_ENST00000359697 STYXL1 Q9Y6J8 Serine/threonine/tyrosine-interacting-like protein 1 chr7 GO:0030234 Not Cancer Driver No 55 0.176 18 3 0.167 0
TAL1 TAL1 P17542 T-cell acute lymphocytic leukemia protein 1 chr1 GO:0030234 Census Yes 54 0.163 305 53 0.174 0
TANK TANK Q92844 TRAF family member-associated NF-kappa-B activator chr2 GO:0030234 Not Cancer Driver No 42 0.099 302 26 0.086 0
TEFM TEFM Q96QE5 Transcription elongation factor, mitochondrial chr17 GO:0030234 Not Cancer Driver No 37 0.103 26 5 0.192 0
TEN1 TEN1 Q86WV5 CST complex subunit TEN1 chr17 GO:0030234 Not Cancer Driver No 6 0.049 8 4 0.5 0
TIMP1 TIMP1 P01033 Metalloproteinase inhibitor 1 chrX GO:0030234 Not Cancer Driver No 25 0.121 0 0 0.0 0
TIMP2 TIMP2 P16035 Metalloproteinase inhibitor 2 chr17 GO:0030234 Not Cancer Driver No 31 0.141 6 2 0.333 0
TIMP3 TIMP3 P35625 Metalloproteinase inhibitor 3 chr22 GO:0030234 Not Cancer Driver No 43 0.204 3 1 0.333 5
TIMP4 TIMP4 Q99727 Metalloproteinase inhibitor 4 chr3 GO:0030234 Not Cancer Driver No 30 0.134 8 2 0.25 0
TMBIM6_ENST00000549385 TMBIM6 P55061 Bax inhibitor 1 chr12 GO:0030234 Not Cancer Driver No 16 0.068 3 0 0.0 0
TNFAIP8_ENST00000504771 TNFAIP8 O95379 Tumor necrosis factor alpha-induced protein 8 chr5 GO:0030234 Not Cancer Driver No 21 0.106 13 1 0.077 0
TNFSF14 TNFSF14 O43557 Tumor necrosis factor ligand superfamily member 14 chr19 GO:0030234 Not Cancer Driver No 58 0.242 18 1 0.056 0
TNK2_ENST00000333602 TNK2 Q07912 Activated CDC42 kinase 1 chr3 GO:0030234 Not Cancer Driver No 137 0.132 593 81 0.137 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 GO:0030234 Census, Compendium Yes 2891 7.356 282 1466 5.199 83
TRIB1 TRIB1 Q96RU8 Tribbles homolog 1 chr8 GO:0030234 Not Cancer Driver No 47 0.126 91 5 0.055 0
TRIB2 TRIB2 Q92519 Tribbles homolog 2 chr2 GO:0030234 Not Cancer Driver No 64 0.187 43 5 0.116 0
TRIB3_ENST00000217233 TRIB3 Q96RU7 Tribbles homolog 3 chr20 GO:0030234 Not Cancer Driver No 65 0.182 114 24 0.211 0
UBE2L3_ENST00000342192 UBE2L3 P68036 Ubiquitin-conjugating enzyme E2 L3 chr22 GO:0030234 Not Cancer Driver No 19 0.123 32 4 0.125 0
UCN UCN P55089 Urocortin chr2 GO:0030234 Not Cancer Driver No 7 0.056 61 4 0.066 0
VCP VCP P55072 Transitional endoplasmic reticulum ATPase chr9 GO:0030234 Not Cancer Driver No 88 0.109 186 16 0.086 16
VIL1 VIL1 P09327 Villin-1 chr2 GO:0030234 Not Cancer Driver No 124 0.15 222 38 0.171 0
VSIR VSIR Q9H7M9 V-type immunoglobulin domain-containing suppressor of T-cell activation chr10 GO:0030234 Not Cancer Driver No 52 0.167 135 19 0.141 0
WARS WARS1 P23381 Tryptophan--tRNA ligase, cytoplasmic chr14 GO:0030234 Not Cancer Driver No 62 0.132 90 13 0.144 1
WDR81 WDR81 Q562E7 WD repeat-containing protein 81 chr17 GO:0030234 Not Cancer Driver No 164 0.084 721 51 0.071 1
WDR91 WDR91 A4D1P6 WD repeat-containing protein 91 chr7 GO:0030234 Not Cancer Driver No 99 0.133 206 38 0.184 0
WFDC2 WFDC2 Q14508 WAP four-disulfide core domain protein 2 chr20 GO:0030234 Not Cancer Driver No 16 0.129 0 0 0.0 0
WFIKKN1 WFIKKN1 Q96NZ8 WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 1 chr16 GO:0030234 Not Cancer Driver No 38 0.069 90 4 0.044 0
WFIKKN2 WFIKKN2 Q8TEU8 WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 chr17 GO:0030234 Not Cancer Driver No 114 0.198 94 32 0.34 0
XIAP_ENST00000434753 XIAP P98170 E3 ubiquitin-protein ligase XIAP chrX GO:0030234 Not Cancer Driver No 89 0.179 55 6 0.109 0
YWHAG YWHAG P61981 14-3-3 protein gamma chr7 GO:0030234 Not Cancer Driver No 26 0.105 77 9 0.117 2