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Total number of protein in "GO:0030217" GO term:  112

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ADAM17 ADAM17 P78536 Disintegrin and metalloproteinase domain-containing protein 17 chr2 GO:0030217 Not Cancer Driver No 80 0.097 182 17 0.093 0
ARMC5_ENST00000563544 ARMC5 Q96C12 Armadillo repeat-containing protein 5 chr16 GO:0030217 Not Cancer Driver No 135 0.144 267 41 0.154 17
ATF2 ATF2 P15336 Cyclic AMP-dependent transcription factor ATF-2 chr2 GO:0030217 Not Cancer Driver No 65 0.129 451 58 0.129 0
ATP7A ATP7A Q04656 Copper-transporting ATPase 1 chrX GO:0030217 Not Cancer Driver No 228 0.152 171 46 0.269 52
B2M B2M P61769 Beta-2-microglobulin chr15 GO:0030217 Census, Compendium Yes 34 0.286 5 1 0.2 2
BATF BATF Q16520 Basic leucine zipper transcriptional factor ATF-like chr14 GO:0030217 Not Cancer Driver No 28 0.224 119 25 0.21 0
BCL11B BCL11B Q9C0K0 B-cell lymphoma/leukemia 11B chr14 GO:0030217 Census, Compendium Yes 156 0.174 699 114 0.163 2
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:0030217 Census, Compendium Yes 24 0.1 72 5 0.069 0
BCL3 BCL3 P20749 B-cell lymphoma 3 protein chr19 GO:0030217 Census Yes 44 0.097 259 23 0.089 0
CCR6_ENST00000349984 CCR6 P51684 C-C chemokine receptor type 6 chr6 GO:0030217 Not Cancer Driver No 56 0.15 13 2 0.154 0
CCR9 CCR9 P51686 C-C chemokine receptor type 9 chr3 GO:0030217 Not Cancer Driver No 60 0.163 0 0 0.0 0
CD28 CD28 P10747 T-cell-specific surface glycoprotein CD28 chr2 GO:0030217 Census Yes 42 0.191 18 10 0.556 0
CD4 CD4 P01730 T-cell surface glycoprotein CD4 chr12 GO:0030217 Not Cancer Driver No 69 0.151 56 11 0.196 0
CD8A_ENST00000283635 CD8A P01732 T-cell surface glycoprotein CD8 alpha chain chr2 GO:0030217 Not Cancer Driver No 33 0.14 28 2 0.071 1
CDK6 CDK6 Q00534 Cyclin-dependent kinase 6 chr7 GO:0030217 Census Yes 40 0.123 24 3 0.125 1
CHD7 CHD7 Q9P2D1 Chromodomain-helicase-DNA-binding protein 7 chr8 GO:0030217 Not Cancer Driver No 464 0.155 1872 299 0.16 50
CLEC4D CLEC4D Q8WXI8 C-type lectin domain family 4 member D chr12 GO:0030217 Not Cancer Driver No 59 0.274 17 3 0.176 0
CLEC4E CLEC4E Q9ULY5 C-type lectin domain family 4 member E chr12 GO:0030217 Not Cancer Driver No 56 0.256 5 2 0.4 0
CRACR2A CRACR2A Q9BSW2 EF-hand calcium-binding domain-containing protein 4B chr12 GO:0030217 Not Cancer Driver No 88 0.12 436 60 0.138 0
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 GO:0030217 Census, Compendium Yes 415 0.531 288 301 1.045 14
DLL4 DLL4 Q9NR61 Delta-like protein 4 chr15 GO:0030217 Not Cancer Driver No 75 0.109 73 15 0.205 7
DNAJA3 DNAJA3 Q96EY1 DnaJ homolog subfamily A member 3, mitochondrial chr16 GO:0030217 Not Cancer Driver No 50 0.104 152 21 0.138 0
EGR1 EGR1 P18146 Early growth response protein 1 chr5 GO:0030217 Not Cancer Driver No 78 0.144 501 72 0.144 0
ENTPD7 ENTPD7 Q9NQZ7 Ectonucleoside triphosphate diphosphohydrolase 7 chr10 GO:0030217 Not Cancer Driver No 90 0.149 26 3 0.115 0
EOMES_ENST00000295743 EOMES O95936 Eomesodermin homolog chr3 GO:0030217 Not Cancer Driver No 82 0.12 436 50 0.115 0
FADD FADD Q13158 FAS-associated death domain protein chr11 GO:0030217 Not Cancer Driver No 26 0.125 45 10 0.222 1
FCER1G FCER1G P30273 High affinity immunoglobulin epsilon receptor subunit gamma chr1 GO:0030217 Not Cancer Driver No 10 0.116 13 2 0.154 0
FOXP1_ENST00000318789 FOXP1 Q9H334 Forkhead box protein P1 chr3 GO:0030217 Census, Compendium Yes 109 0.161 448 71 0.158 3
FUT7 FUT7 Q11130 Alpha-(1,3)-fucosyltransferase 7 chr9 GO:0030217 Not Cancer Driver No 28 0.082 25 3 0.12 0
FZD5 FZD5 Q13467 Frizzled-5 chr2 GO:0030217 Not Cancer Driver No 45 0.077 58 4 0.069 0
FZD7 FZD7 O75084 Frizzled-7 chr2 GO:0030217 Not Cancer Driver No 90 0.157 22 2 0.091 0
FZD8 FZD8 Q9H461 Frizzled-8 chr10 GO:0030217 Not Cancer Driver No 72 0.104 146 3 0.021 0
GATA3_ENST00000346208 GATA3 P23771 Trans-acting T-cell-specific transcription factor GATA-3 chr10 GO:0030217 Census, Compendium Yes 111 0.251 364 87 0.239 2
GBA_ENST00000368373 GBA P04062 Lysosomal acid glucosylceramidase chr1 GO:0030217 Not Cancer Driver No 74 0.138 38 5 0.132 171
GLI3 GLI3 P10071 Transcriptional activator GLI3 chr7 GO:0030217 Not Cancer Driver No 385 0.244 1352 327 0.242 7
GPR183 GPR183 P32249 G-protein coupled receptor 183 chr13 GO:0030217 Not Cancer Driver No 53 0.147 25 3 0.12 0
GPR18_ENST00000397470 GPR18 Q14330 N-arachidonyl glycine receptor chr13 GO:0030217 Not Cancer Driver No 36 0.109 0 0 0.0 0
GPR89A GPR89A B7ZAQ6 Golgi pH regulator A chr1 GO:0030217 Not Cancer Driver No 22 0.048 1 0 0.0 0
GPR89B GPR89B P0CG08 Golgi pH regulator B chr1 GO:0030217 Not Cancer Driver No 11 0.024 1 0 0.0 0
HMGB1_ENST00000405805 HMGB1 P09429 High mobility group protein B1 chr13 GO:0030217 Not Cancer Driver No 25 0.116 203 20 0.099 0
IL12B IL12B P29460 Interleukin-12 subunit beta chr5 GO:0030217 Not Cancer Driver No 48 0.146 42 2 0.048 0
IL18R1_ENST00000233957 IL18R1 Q13478 Interleukin-18 receptor 1 chr2 GO:0030217 Not Cancer Driver No 104 0.192 18 3 0.167 0
IL2 IL2 P60568 Interleukin-2 chr4 GO:0030217 Census Yes 24 0.157 6 1 0.167 0
IL21 IL21 Q9HBE4 Interleukin-21 chr4 GO:0030217 Not Cancer Driver No 34 0.21 70 18 0.257 1
IL4 IL4 P05112 Interleukin-4 chr5 GO:0030217 Not Cancer Driver No 18 0.118 0 0 0.0 0
IL6 IL6 P05231 Interleukin-6 chr7 GO:0030217 Not Cancer Driver No 35 0.165 58 7 0.121 0
IL7R IL7R P16871 Interleukin-7 receptor subunit alpha chr5 GO:0030217 Census, Compendium Yes 177 0.386 88 48 0.545 1
IRF1 IRF1 P10914 Interferon regulatory factor 1 chr5 GO:0030217 Compendium Yes 49 0.151 228 31 0.136 2
ITK ITK Q08881 Tyrosine-protein kinase ITK/TSK chr5 GO:0030217 Census Yes 139 0.224 43 10 0.233 1
JAG2 JAG2 Q9Y219 Protein jagged-2 chr14 GO:0030217 Not Cancer Driver No 126 0.102 158 24 0.152 0
JMJD6_ENST00000397625 JMJD6 Q6NYC1 Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 chr17 GO:0030217 Not Cancer Driver No 51 0.127 133 21 0.158 0
KDELR1 KDELR1 P24390 ER lumen protein-retaining receptor 1 chr19 GO:0030217 Not Cancer Driver No 32 0.151 0 0 0.0 0
KIT KIT P10721 Mast/stem cell growth factor receptor Kit chr4 GO:0030217 Census, Compendium Yes 226 0.232 83 33 0.398 21
KLRC1 KLRC1 P26715 NKG2-A/NKG2-B type II integral membrane protein chr12 GO:0030217 Not Cancer Driver No 49 0.21 49 10 0.204 0
LCK LCK P06239 Tyrosine-protein kinase Lck chr1 GO:0030217 Census Yes 86 0.169 94 13 0.138 1
LEF1 LEF1 Q9UJU2 Lymphoid enhancer-binding factor 1 chr4 GO:0030217 Census Yes 64 0.16 370 57 0.154 0
LEP LEP P41159 Leptin chr7 GO:0030217 Not Cancer Driver No 29 0.174 0 0 0.0 2
LEPR LEPR P48357 Leptin receptor chr1 GO:0030217 Not Cancer Driver No 243 0.209 57 11 0.193 0
LFNG LFNG Q8NES3 Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe chr7 GO:0030217 Not Cancer Driver No 37 0.098 65 1 0.015 1
LIG4 LIG4 P49917 DNA ligase 4 chr13 GO:0030217 Not Cancer Driver No 134 0.147 63 10 0.159 2
LMBR1L LMBR1L Q6UX01 Protein LMBR1L chr12 GO:0030217 Not Cancer Driver No 57 0.117 4 0 0.0 0
MAFB MAFB Q9Y5Q3 Transcription factor MafB chr20 GO:0030217 Census Yes 35 0.108 301 34 0.113 10
MR1 MR1 Q95460 Major histocompatibility complex class I-related gene protein chr1 GO:0030217 Not Cancer Driver No 60 0.176 33 7 0.212 0
NCAPH2_ENST00000420993 NCAPH2 Q6IBW4 Condensin-2 complex subunit H2 chr22 GO:0030217 Not Cancer Driver No 67 0.111 335 39 0.116 0
NHEJ1 NHEJ1 Q9H9Q4 Non-homologous end-joining factor 1 chr2 GO:0030217 Not Cancer Driver No 35 0.117 83 8 0.096 2
NKAP NKAP Q8N5F7 NF-kappa-B-activating protein chrX GO:0030217 Not Cancer Driver No 80 0.193 409 77 0.188 3
NKX2-3 NKX2-3 Q8TAU0 Homeobox protein Nkx-2.3 chr10 GO:0030217 Not Cancer Driver No 31 0.085 212 27 0.127 0
PATZ1 PATZ1 Q9HBE1 POZ-, AT hook-, and zinc finger-containing protein 1 chr22 GO:0030217 Census Yes 91 0.132 301 38 0.126 0
PIK3CD PIK3CD O00329 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform chr1 GO:0030217 Not Cancer Driver No 140 0.134 60 13 0.217 1
PKNOX1 PKNOX1 P55347 Homeobox protein PKNOX1 chr21 GO:0030217 Not Cancer Driver No 60 0.138 279 36 0.129 0
PLA2G2D PLA2G2D Q9UNK4 Group IID secretory phospholipase A2 chr1 GO:0030217 Not Cancer Driver No 27 0.186 0 0 0.0 0
PPP3CB_ENST00000360663 PPP3CB P16298 Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform chr10 GO:0030217 Not Cancer Driver No 67 0.128 139 18 0.129 0
PREX1 PREX1 Q8TCU6 Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein chr20 GO:0030217 Not Cancer Driver No 297 0.179 307 55 0.179 0
PRKDC PRKDC P78527 DNA-dependent protein kinase catalytic subunit chr8 GO:0030217 Not Cancer Driver No 538 0.13 421 61 0.145 2
PRR7_ENST00000502922 PRR7 Q8TB68 Proline-rich protein 7 chr5 GO:0030217 Not Cancer Driver No 10 0.036 199 6 0.03 0
PSMB11 PSMB11 A5LHX3 Proteasome subunit beta type-11 chr14 GO:0030217 Not Cancer Driver No 62 0.207 71 11 0.155 0
PTGER4 PTGER4 P35408 Prostaglandin E2 receptor EP4 subtype chr5 GO:0030217 Not Cancer Driver No 81 0.166 118 17 0.144 0
PTPN2 PTPN2 P17706 Tyrosine-protein phosphatase non-receptor type 2 chr18 GO:0030217 Not Cancer Driver No 57 0.137 120 14 0.117 0
PTPN22 PTPN22 Q9Y2R2 Tyrosine-protein phosphatase non-receptor type 22 chr1 GO:0030217 Not Cancer Driver No 141 0.175 364 62 0.17 4
PTPRC PTPRC P08575 Receptor-type tyrosine-protein phosphatase C chr1 GO:0030217 Census, Compendium Yes 315 0.241 462 107 0.232 0
RABL3 RABL3 Q5HYI8 Rab-like protein 3 chr3 GO:0030217 Not Cancer Driver No 37 0.157 1 0 0.0 1
RAG1 RAG1 P15918 V(D)J recombination-activating protein 1 chr11 GO:0030217 Not Cancer Driver No 204 0.196 208 43 0.207 36
RAG2 RAG2 P55895 V(D)J recombination-activating protein 2 chr11 GO:0030217 Not Cancer Driver No 118 0.224 85 23 0.271 6
RC3H1_ENST00000258349 RC3H1 Q5TC82 Roquin-1 chr1 GO:0030217 Not Cancer Driver No 158 0.139 796 115 0.144 0
RC3H2_ENST00000357244 RC3H2 Q9HBD1 Roquin-2 chr9 GO:0030217 Not Cancer Driver No 128 0.107 703 81 0.115 0
RELB RELB Q01201 Transcription factor RelB chr19 GO:0030217 Not Cancer Driver No 65 0.112 348 39 0.112 0
RHOH_ENST00000617441 RHOH Q15669 Rho-related GTP-binding protein RhoH chr4 GO:0030217 Census Yes 41 0.215 12 3 0.25 0
RIPK3 RIPK3 Q9Y572 Receptor-interacting serine/threonine-protein kinase 3 chr14 GO:0030217 Not Cancer Driver No 66 0.127 295 39 0.132 0
RORA_ENST00000335670 RORA P35398 Nuclear receptor ROR-alpha chr15 GO:0030217 Not Cancer Driver No 57 0.109 182 17 0.093 4
RORC RORC P51449 Nuclear receptor ROR-gamma chr1 GO:0030217 Not Cancer Driver No 96 0.185 187 36 0.193 1
RPS6 RPS6 P62753 40S ribosomal protein S6 chr9 GO:0030217 Not Cancer Driver No 38 0.153 150 25 0.167 0
RSAD2 RSAD2 Q8WXG1 Radical S-adenosyl methionine domain-containing protein 2 chr2 GO:0030217 Not Cancer Driver No 68 0.188 22 1 0.045 0
RUNX2_ENST00000647337 RUNX2 Q13950 Runt-related transcription factor 2 chr6 GO:0030217 Not Cancer Driver No 83 0.159 447 73 0.163 47
SEMA4A_ENST00000355014 SEMA4A Q9H3S1 Semaphorin-4A chr1 GO:0030217 Not Cancer Driver No 123 0.162 122 26 0.213 4
SHH SHH Q15465 Sonic hedgehog protein chr7 GO:0030217 Not Cancer Driver No 56 0.121 139 14 0.101 81
SOX13 SOX13 Q9UN79 Transcription factor SOX-13 chr1 GO:0030217 Not Cancer Driver No 85 0.137 564 77 0.137 0
SOX4 SOX4 Q06945 Transcription factor SOX-4 chr6 GO:0030217 Not Cancer Driver No 28 0.059 400 24 0.06 4
SP3 SP3 Q02447 Transcription factor Sp3 chr2 GO:0030217 Not Cancer Driver No 66 0.085 587 37 0.063 0
STAT5B STAT5B P51692 Signal transducer and activator of transcription 5B chr17 GO:0030217 Census, Compendium Yes 93 0.118 144 19 0.132 5
TCIRG1 TCIRG1 Q13488 V-type proton ATPase 116 kDa subunit a 3 chr11 GO:0030217 Compendium Yes 68 0.082 102 6 0.059 5
TESPA1 TESPA1 A2RU30 Protein TESPA1 chr12 GO:0030217 Not Cancer Driver No 127 0.244 284 84 0.296 0
TMEM98 TMEM98 Q9Y2Y6 Transmembrane protein 98 chr17 GO:0030217 Not Cancer Driver No 39 0.173 27 3 0.111 2
TNFSF8 TNFSF8 P32971 Tumor necrosis factor ligand superfamily member 8 chr9 GO:0030217 Not Cancer Driver No 34 0.145 30 2 0.067 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 GO:0030217 Census, Compendium Yes 2891 7.356 282 1466 5.199 83
TRAF3IP2_ENST00000392556 TRAF3IP2 O43734 E3 ubiquitin ligase TRAF3IP2 chr6 GO:0030217 Not Cancer Driver No 59 0.103 410 39 0.095 2
TSC1 TSC1 Q92574 Hamartin chr9 GO:0030217 Census, Compendium Yes 135 0.116 732 78 0.107 11
VAV1 VAV1 P15498 Proto-oncogene vav chr19 GO:0030217 Census, Compendium Yes 165 0.195 113 19 0.168 0
WNT1 WNT1 P04628 Proto-oncogene Wnt-1 chr12 GO:0030217 Not Cancer Driver No 29 0.078 25 0 0.0 8
ZAP70 ZAP70 P43403 Tyrosine-protein kinase ZAP-70 chr2 GO:0030217 Not Cancer Driver No 126 0.204 117 17 0.145 8
ZBTB7B_ENST00000368426 ZBTB7B O15156 Zinc finger and BTB domain-containing protein 7B chr1 GO:0030217 Compendium Yes 103 0.191 353 70 0.198 0
ZFP36L1 ZFP36L1 Q07352 mRNA decay activator protein ZFP36L1 chr14 GO:0030217 Compendium Yes 57 0.169 212 30 0.142 0
ZFP36L2 ZFP36L2 P47974 mRNA decay activator protein ZFP36L2 chr2 GO:0030217 Not Cancer Driver No 73 0.148 324 45 0.139 0