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Total number of protein in "GO:0030182" GO term:  264

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABT1 ABT1 Q9ULW3 Activator of basal transcription 1 chr6 GO:0030182 Not Cancer Driver No 56 0.206 157 30 0.191 0
ACSL3 ACSL3 O95573 Fatty acid CoA ligase Acsl3 chr2 GO:0030182 Census, Compendium Yes 89 0.124 47 7 0.149 0
ACSL4_ENST00000469796 ACSL4 O60488 Long-chain-fatty-acid--CoA ligase 4 chrX GO:0030182 Not Cancer Driver No 97 0.136 77 12 0.156 1
ADNP2 ADNP2 Q6IQ32 Activity-dependent neuroprotector homeobox protein 2 chr18 GO:0030182 Not Cancer Driver No 133 0.118 475 53 0.112 0
AGTPBP1_ENST00000357081 AGTPBP1 Q9UPW5 Cytosolic carboxypeptidase 1 chr9 GO:0030182 Not Cancer Driver No 158 0.129 321 42 0.131 4
ALDH1A2 ALDH1A2 O94788 Retinal dehydrogenase 2 chr15 GO:0030182 Not Cancer Driver No 100 0.193 56 13 0.232 0
ANOS1 ANOS1 P23352 Anosmin-1 chrX GO:0030182 Not Cancer Driver No 124 0.182 195 44 0.226 14
ASCL1 ASCL1 P50553 Achaete-scute homolog 1 chr12 GO:0030182 Not Cancer Driver No 33 0.14 182 24 0.132 0
ASCL2 ASCL2 Q99929 Achaete-scute homolog 2 chr11 GO:0030182 Not Cancer Driver No 2 0.01 166 1 0.006 0
ATF4_ENST00000404241 ATF4 P18848 Cyclic AMP-dependent transcription factor ATF-4 chr22 GO:0030182 Not Cancer Driver No 53 0.151 259 38 0.147 0
ATOH1 ATOH1 Q92858 Transcription factor ATOH1 chr4 GO:0030182 Not Cancer Driver No 63 0.178 327 55 0.168 0
ATOH7 ATOH7 Q8N100 Transcription factor ATOH7 chr10 GO:0030182 Not Cancer Driver No 10 0.066 40 3 0.075 2
ATOH8 ATOH8 Q96SQ7 Transcription factor ATOH8 chr2 GO:0030182 Not Cancer Driver No 31 0.097 254 23 0.091 0
ATP2B2 ATP2B2 Q01814 Plasma membrane calcium-transporting ATPase 2 chr3 GO:0030182 Not Cancer Driver No 248 0.2 360 82 0.228 0
ATP7A ATP7A Q04656 Copper-transporting ATPase 1 chrX GO:0030182 Not Cancer Driver No 228 0.152 171 46 0.269 52
BARHL2 BARHL2 Q9NY43 BarH-like 2 homeobox protein chr1 GO:0030182 Not Cancer Driver No 72 0.186 345 65 0.188 0
BCL11B BCL11B Q9C0K0 B-cell lymphoma/leukemia 11B chr14 GO:0030182 Census, Compendium Yes 156 0.174 699 114 0.163 2
BHLHA15 BHLHA15 Q7RTS1 Class A basic helix-loop-helix protein 15 chr7 GO:0030182 Not Cancer Driver No 12 0.063 183 12 0.066 0
BHLHE22 BHLHE22 Q8NFJ8 Class E basic helix-loop-helix protein 22 chr8 GO:0030182 Not Cancer Driver No 41 0.108 269 23 0.086 0
BHLHE23_ENST00000370346 BHLHE23 Q8NDY6 Class E basic helix-loop-helix protein 23 chr20 GO:0030182 Not Cancer Driver No 16 0.071 119 9 0.076 0
BLOC1S2 BLOC1S2 Q6QNY1 Biogenesis of lysosome-related organelles complex 1 subunit 2 chr10 GO:0030182 Not Cancer Driver No 17 0.12 34 6 0.176 0
BMP4 BMP4 P12644 Bone morphogenetic protein 4 chr14 GO:0030182 Not Cancer Driver No 86 0.211 142 26 0.183 5
BRSK1 BRSK1 Q8TDC3 Serine/threonine-protein kinase BRSK1 chr19 GO:0030182 Not Cancer Driver No 131 0.168 459 78 0.17 0
BRSK2_ENST00000528841 BRSK2 Q8IWQ3 Serine/threonine-protein kinase BRSK2 chr11 GO:0030182 Not Cancer Driver No 90 0.122 321 39 0.121 0
BTG4 BTG4 Q9NY30 Protein BTG4 chr11 GO:0030182 Not Cancer Driver No 43 0.193 33 5 0.152 1
C21orf91 EURL Q9NYK6 Protein EURL homolog chr21 GO:0030182 Not Cancer Driver No 31 0.104 120 15 0.125 0
CABP4 CABP4 P57796 Calcium-binding protein 4 chr11 GO:0030182 Not Cancer Driver No 61 0.222 188 47 0.25 1
CASP3 CASP3 P42574 Caspase-3 chr4 GO:0030182 Census Yes 32 0.116 62 5 0.081 0
CBLN1 CBLN1 P23435 Cerebellin-1 chr16 GO:0030182 Not Cancer Driver No 46 0.238 14 2 0.143 0
CDK5 CDK5 Q00535 Cyclin-dependent kinase 5 chr7 GO:0030182 Not Cancer Driver No 48 0.164 5 1 0.2 0
CDK5R1 CDK5R1 Q15078 Cyclin-dependent kinase 5 activator 1 chr17 GO:0030182 Not Cancer Driver No 35 0.114 103 16 0.155 0
CEBPB CEBPB P17676 CCAAT/enhancer-binding protein beta chr20 GO:0030182 Not Cancer Driver No 3 0.009 276 2 0.007 0
CEND1 CEND1 Q8N111 Cell cycle exit and neuronal differentiation protein 1 chr11 GO:0030182 Not Cancer Driver No 13 0.087 124 10 0.081 0
CHD5 CHD5 Q8TDI0 Chromodomain-helicase-DNA-binding protein 5 chr1 GO:0030182 Not Cancer Driver No 365 0.187 931 183 0.197 0
CLN8 CLN8 Q9UBY8 Protein CLN8 chr8 GO:0030182 Not Cancer Driver No 45 0.157 16 2 0.125 16
COPS2_ENST00000388901 COPS2 P61201 COP9 signalosome complex subunit 2 chr15 GO:0030182 Not Cancer Driver No 59 0.133 59 9 0.153 0
CSF1R CSF1R P07333 Macrophage colony-stimulating factor 1 receptor chr5 GO:0030182 Census Yes 133 0.137 124 17 0.137 20
CTF1 CTF1 Q16619 Cardiotrophin-1 chr16 GO:0030182 Not Cancer Driver No 6 0.03 90 4 0.044 0
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 GO:0030182 Census, Compendium Yes 415 0.531 288 301 1.045 14
DDIT4 DDIT4 Q9NX09 DNA damage-inducible transcript 4 protein chr10 GO:0030182 Not Cancer Driver No 20 0.086 87 9 0.103 0
DLX1 DLX1 P56177 Homeobox protein DLX-1 chr2 GO:0030182 Not Cancer Driver No 25 0.098 183 21 0.115 0
DLX2 DLX2 Q07687 Homeobox protein DLX-2 chr2 GO:0030182 Not Cancer Driver No 46 0.14 262 38 0.145 0
DLX5 DLX5 P56178 Homeobox protein DLX-5 chr7 GO:0030182 Not Cancer Driver No 71 0.246 223 57 0.256 1
DMRTA2_ENST00000418121 DMRTA2 Q96SC8 Doublesex- and mab-3-related transcription factor A2 chr1 GO:0030182 Not Cancer Driver No 25 0.046 325 19 0.058 0
DNMT3A DNMT3A Q9Y6K1 DNA (cytosine-5)-methyltransferase 3A chr2 GO:0030182 Census, Compendium Yes 194 0.213 371 59 0.159 16
DOK5 DOK5 Q9P104 Docking protein 5 chr20 GO:0030182 Not Cancer Driver No 87 0.284 15 7 0.467 0
DRAXIN DRAXIN Q8NBI3 Draxin chr1 GO:0030182 Not Cancer Driver No 61 0.175 249 48 0.193 0
DSCAM DSCAM O60469 Down syndrome cell adhesion molecule chr21 GO:0030182 Not Cancer Driver No 652 0.324 603 201 0.333 0
DTNB DTNB O60941 Dystrobrevin beta chr2 GO:0030182 Not Cancer Driver No 75 0.12 337 42 0.125 0
DYNC2H1_ENST00000375735 DYNC2H1 Q8NCM8 Cytoplasmic dynein 2 heavy chain 1 chr11 GO:0030182 Not Cancer Driver No 510 0.118 282 15 0.053 34
EDN1 EDN1 P05305 Endothelin-1 chr6 GO:0030182 Not Cancer Driver No 37 0.175 97 20 0.206 3
EDNRA EDNRA P25101 Endothelin-1 receptor chr4 GO:0030182 Not Cancer Driver No 62 0.145 21 6 0.286 2
ELAVL4_ENST00000371821 ELAVL4 P26378 ELAV-like protein 4 chr1 GO:0030182 Not Cancer Driver No 118 0.306 117 34 0.291 0
EMX1 EMX1 Q04741 Homeobox protein EMX1 chr2 GO:0030182 Not Cancer Driver No 26 0.09 162 20 0.123 0
EMX2 EMX2 Q04743 Homeobox protein EMX2 chr10 GO:0030182 Not Cancer Driver No 34 0.135 147 21 0.143 0
EN1 EN1 Q05925 Homeobox protein engrailed-1 chr2 GO:0030182 Not Cancer Driver No 42 0.107 357 30 0.084 0
EN2 EN2 P19622 Homeobox protein engrailed-2 chr7 GO:0030182 Not Cancer Driver No 23 0.069 317 23 0.073 0
EOMES_ENST00000295743 EOMES O95936 Eomesodermin homolog chr3 GO:0030182 Not Cancer Driver No 82 0.12 436 50 0.115 0
ERBB2 ERBB2 P04626 Receptor tyrosine-protein kinase erbB-2 chr17 GO:0030182 Census, Compendium Yes 275 0.219 314 41 0.131 1
ERBB4 ERBB4 Q15303 Receptor tyrosine-protein kinase erbB-4 chr2 GO:0030182 Census, Compendium Yes 428 0.327 323 116 0.359 2
ERCC2 ERCC2 P18074 General transcription and DNA repair factor IIH helicase subunit XPD chr19 GO:0030182 Census, Compendium Yes 150 0.197 5 0 0.0 35
ERCC3 ERCC3 P19447 General transcription and DNA repair factor IIH helicase subunit XPB chr2 GO:0030182 Census, Compendium Yes 92 0.118 208 22 0.106 2
ERCC6 ERCC6 Q03468 DNA excision repair protein ERCC-6 chr10 GO:0030182 Not Cancer Driver No 211 0.141 829 117 0.141 9
FAIM2 FAIM2 Q9BWQ8 Protein lifeguard 2 chr12 GO:0030182 Not Cancer Driver No 37 0.117 54 11 0.204 0
FGF20 FGF20 Q9NP95 Fibroblast growth factor 20 chr8 GO:0030182 Not Cancer Driver No 25 0.118 57 3 0.053 0
FGF8_ENST00000344255 FGF8 P55075 Fibroblast growth factor 8 chr10 GO:0030182 Not Cancer Driver No 30 0.129 79 9 0.114 6
FOXA1 FOXA1 P55317 Hepatocyte nuclear factor 3-alpha chr14 GO:0030182 Census, Compendium Yes 100 0.212 295 53 0.18 0
FOXA2_ENST00000377115 FOXA2 Q9Y261 Hepatocyte nuclear factor 3-beta chr20 GO:0030182 Compendium Yes 70 0.153 258 34 0.132 0
FOXN4 FOXN4 Q96NZ1 Forkhead box protein N4 chr12 GO:0030182 Not Cancer Driver No 60 0.116 377 34 0.09 0
FUT9 FUT9 Q9Y231 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9 chr6 GO:0030182 Not Cancer Driver No 153 0.426 0 0 0.0 0
FZD1 FZD1 Q9UP38 Frizzled-1 chr7 GO:0030182 Not Cancer Driver No 78 0.121 133 2 0.015 0
FZD10 FZD10 Q9ULW2 Frizzled-10 chr12 GO:0030182 Not Cancer Driver No 148 0.255 65 15 0.231 0
FZD2 FZD2 Q14332 Frizzled-2 chr17 GO:0030182 Not Cancer Driver No 85 0.15 47 5 0.106 1
FZD3_ENST00000240093 FZD3 Q9NPG1 Frizzled-3 chr8 GO:0030182 Not Cancer Driver No 64 0.096 141 13 0.092 0
FZD4 FZD4 Q9ULV1 Frizzled-4 chr11 GO:0030182 Not Cancer Driver No 57 0.106 33 5 0.152 19
FZD5 FZD5 Q13467 Frizzled-5 chr2 GO:0030182 Not Cancer Driver No 45 0.077 58 4 0.069 0
FZD7 FZD7 O75084 Frizzled-7 chr2 GO:0030182 Not Cancer Driver No 90 0.157 22 2 0.091 0
FZD8 FZD8 Q9H461 Frizzled-8 chr10 GO:0030182 Not Cancer Driver No 72 0.104 146 3 0.021 0
GATA2_ENST00000487848 GATA2 P23769 Endothelial transcription factor GATA-2 chr3 GO:0030182 Census, Compendium Yes 72 0.15 370 49 0.132 6
GBA_ENST00000368373 GBA P04062 Lysosomal acid glucosylceramidase chr1 GO:0030182 Not Cancer Driver No 74 0.138 38 5 0.132 171
GBX1 GBX1 Q14549 Homeobox protein GBX-1 chr7 GO:0030182 Not Cancer Driver No 40 0.11 267 28 0.105 0
GDF7 GDF7 Q7Z4P5 Growth/differentiation factor 7 chr2 GO:0030182 Not Cancer Driver No 33 0.073 213 8 0.038 0
GIGYF2_ENST00000409547 GIGYF2 Q6Y7W6 GRB10-interacting GYF protein 2 chr2 GO:0030182 Not Cancer Driver No 176 0.135 1096 158 0.144 6
GPC2 GPC2 Q8N158 Glypican-2 chr7 GO:0030182 Not Cancer Driver No 57 0.098 199 16 0.08 0
GRID2 GRID2 O43424 Glutamate receptor ionotropic, delta-2 chr4 GO:0030182 Not Cancer Driver No 350 0.348 155 35 0.226 3
GRXCR1 GRXCR1 A8MXD5 Glutaredoxin domain-containing cysteine-rich protein 1 chr4 GO:0030182 Not Cancer Driver No 139 0.479 73 45 0.616 4
GSDME_ENST00000409775 GSDME O60443 Gasdermin-E chr7 GO:0030182 Not Cancer Driver No 81 0.163 14 3 0.214 0
GSX1 GSX1 Q9H4S2 GS homeobox 1 chr13 GO:0030182 Not Cancer Driver No 26 0.098 137 14 0.102 0
GSX2 GSX2 Q9BZM3 GS homeobox 2 chr4 GO:0030182 Not Cancer Driver No 44 0.145 210 26 0.124 1
HAND2 HAND2 P61296 Heart- and neural crest derivatives-expressed protein 2 chr4 GO:0030182 Not Cancer Driver No 47 0.217 124 29 0.234 0
HDAC1 HDAC1 Q13547 Histone deacetylase 1 chr1 GO:0030182 Not Cancer Driver No 47 0.098 135 10 0.074 0
HELT HELT A6NFD8 Hairy and enhancer of split-related protein HELT chr4 GO:0030182 Not Cancer Driver No 39 0.161 131 21 0.16 0
HERC1 HERC1 Q15751 Probable E3 ubiquitin-protein ligase HERC1 chr15 GO:0030182 Not Cancer Driver No 487 0.1 1344 129 0.096 1
HES1 HES1 Q14469 Transcription factor HES-1 chr3 GO:0030182 Not Cancer Driver No 37 0.132 226 32 0.142 0
HIF1A_ENST00000337138 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 GO:0030182 Census Yes 118 0.143 435 51 0.117 0
HIPK1_ENST00000426820 HIPK1 Q86Z02 Homeodomain-interacting protein kinase 1 chr1 GO:0030182 Not Cancer Driver No 158 0.131 565 89 0.158 0
HIPK2 HIPK2 Q9H2X6 Homeodomain-interacting protein kinase 2 chr7 GO:0030182 Not Cancer Driver No 154 0.129 686 96 0.14 0
HOXC8 HOXC8 P31273 Homeobox protein Hox-C8 chr12 GO:0030182 Not Cancer Driver No 38 0.157 139 19 0.137 0
HOXD1 HOXD1 Q9GZZ0 Homeobox protein Hox-D1 chr2 GO:0030182 Not Cancer Driver No 39 0.119 124 17 0.137 0
HPRT1 HPRT1 P00492 Hypoxanthine-guanine phosphoribosyltransferase chrX GO:0030182 Not Cancer Driver No 22 0.101 3 0 0.0 62
HSPA5 HSPA5 P11021 Endoplasmic reticulum chaperone BiP chr9 GO:0030182 Not Cancer Driver No 73 0.112 282 35 0.124 0
ID1 ID1 P41134 DNA-binding protein inhibitor ID-1 chr20 GO:0030182 Not Cancer Driver No 20 0.129 17 6 0.353 0
ID3 ID3 Q02535 DNA-binding protein inhibitor ID-3 chr1 GO:0030182 Census, Compendium Yes 14 0.118 34 4 0.118 0
ID4 ID4 P47928 DNA-binding protein inhibitor ID-4 chr6 GO:0030182 Not Cancer Driver No 4 0.025 71 1 0.014 0
IER2_ENST00000587885 IER2 Q9BTL4 Immediate early response gene 2 protein chr19 GO:0030182 Not Cancer Driver No 16 0.072 178 13 0.073 0
IFT172 IFT172 Q9UG01 Intraflagellar transport protein 172 homolog chr2 GO:0030182 Not Cancer Driver No 219 0.125 96 10 0.104 8
IL1RAPL1 IL1RAPL1 Q9NZN1 Interleukin-1 receptor accessory protein-like 1 chrX GO:0030182 Not Cancer Driver No 205 0.295 77 19 0.247 0
INHBA_ENST00000442711 INHBA P08476 Inhibin beta A chain chr7 GO:0030182 Not Cancer Driver No 148 0.347 154 63 0.409 0
INSM1 INSM1 Q01101 Insulinoma-associated protein 1 chr20 GO:0030182 Not Cancer Driver No 25 0.049 359 12 0.033 0
INSM2 INSM2 Q96T92 Insulinoma-associated protein 2 chr14 GO:0030182 Not Cancer Driver No 50 0.088 409 32 0.078 0
IRX1 IRX1 P78414 Iroquois-class homeodomain protein IRX-1 chr5 GO:0030182 Not Cancer Driver No 161 0.335 335 126 0.376 0
IRX2_ENST00000302057 IRX2 Q9BZI1 Iroquois-class homeodomain protein IRX-2 chr5 GO:0030182 Not Cancer Driver No 88 0.187 323 67 0.207 0
IRX3 IRX3 P78415 Iroquois-class homeodomain protein IRX-3 chr16 GO:0030182 Not Cancer Driver No 38 0.076 407 32 0.079 0
IRX4_ENST00000231357 IRX4 P78413 Iroquois-class homeodomain protein IRX-4 chr5 GO:0030182 Not Cancer Driver No 75 0.145 325 58 0.178 0
IRX5 IRX5 P78411 Iroquois-class homeodomain protein IRX-5 chr16 GO:0030182 Not Cancer Driver No 85 0.176 359 62 0.173 2
IRX6 IRX6 P78412 Iroquois-class homeodomain protein IRX-6 chr16 GO:0030182 Not Cancer Driver No 93 0.209 242 49 0.202 0
ISL1 ISL1 P61371 Insulin gene enhancer protein ISL-1 chr5 GO:0030182 Not Cancer Driver No 85 0.244 180 41 0.228 0
ISL2 ISL2 Q96A47 Insulin gene enhancer protein ISL-2 chr15 GO:0030182 Not Cancer Driver No 42 0.117 167 16 0.096 0
ITM2C ITM2C Q9NQX7 Integral membrane protein 2C chr2 GO:0030182 Not Cancer Driver No 31 0.116 33 4 0.121 0
JAG1 JAG1 P78504 Protein jagged-1 chr20 GO:0030182 Not Cancer Driver No 182 0.149 172 20 0.116 52
KNDC1 KNDC1 Q76NI1 Kinase non-catalytic C-lobe domain-containing protein 1 chr10 GO:0030182 Not Cancer Driver No 276 0.158 805 124 0.154 0
LBX1 LBX1 P52954 Transcription factor LBX1 chr10 GO:0030182 Not Cancer Driver No 26 0.093 181 18 0.099 0
LDB1 LDB1 Q86U70 LIM domain-binding protein 1 chr10 GO:0030182 Compendium Yes 56 0.136 177 29 0.164 0
LHX2 LHX2 P50458 LIM/homeobox protein Lhx2 chr9 GO:0030182 Not Cancer Driver No 60 0.148 203 28 0.138 0
LHX3_ENST00000371748 LHX3 Q9UBR4 LIM/homeobox protein Lhx3 chr9 GO:0030182 Not Cancer Driver No 38 0.096 232 14 0.06 2
LHX4 LHX4 Q969G2 LIM/homeobox protein Lhx4 chr1 GO:0030182 Not Cancer Driver No 75 0.192 219 45 0.205 4
LHX5 LHX5 Q9H2C1 LIM/homeobox protein Lhx5 chr12 GO:0030182 Not Cancer Driver No 45 0.112 253 22 0.087 0
LHX6_ENST00000373755 LHX6 Q9UPM6 LIM/homeobox protein Lhx6 chr9 GO:0030182 Not Cancer Driver No 36 0.099 134 10 0.075 0
LHX8 LHX8 Q68G74 LIM/homeobox protein Lhx8 chr1 GO:0030182 Not Cancer Driver No 93 0.261 157 47 0.299 0
LHX9 LHX9 Q9NQ69 LIM/homeobox protein Lhx9 chr1 GO:0030182 Not Cancer Driver No 97 0.244 191 46 0.241 0
LMO4 LMO4 P61968 LIM domain transcription factor LMO4 chr1 GO:0030182 Not Cancer Driver No 30 0.182 11 1 0.091 0
LMX1A_ENST00000294816 LMX1A Q8TE12 LIM homeobox transcription factor 1-alpha chr1 GO:0030182 Not Cancer Driver No 117 0.306 186 65 0.349 1
LMX1B_ENST00000373474 LMX1B O60663 LIM homeobox transcription factor 1-beta chr9 GO:0030182 Not Cancer Driver No 63 0.157 196 30 0.153 32
LRP6 LRP6 O75581 Low-density lipoprotein receptor-related protein 6 chr12 GO:0030182 Not Cancer Driver No 206 0.128 255 30 0.118 5
MANF MANF P55145 Mesencephalic astrocyte-derived neurotrophic factor chr3 GO:0030182 Not Cancer Driver No 14 0.077 1 0 0.0 0
MAP2K1 MAP2K1 Q02750 Dual specificity mitogen-activated protein kinase kinase 1 chr15 GO:0030182 Census, Compendium Yes 94 0.239 96 24 0.25 6
MCOLN3 MCOLN3 Q8TDD5 Mucolipin-3 chr1 GO:0030182 Not Cancer Driver No 102 0.184 9 2 0.222 0
MDGA1 MDGA1 Q8NFP4 MAM domain-containing glycosylphosphatidylinositol anchor protein 1 chr6 GO:0030182 Not Cancer Driver No 148 0.155 312 51 0.163 0
MDGA2 MDGA2 Q7Z553 MAM domain-containing glycosylphosphatidylinositol anchor protein 2 chr14 GO:0030182 Not Cancer Driver No 266 0.278 116 31 0.267 0
MEF2C_ENST00000504921 MEF2C Q06413 Myocyte-specific enhancer factor 2C chr5 GO:0030182 Not Cancer Driver No 92 0.195 408 81 0.199 0
MET_ENST00000397752 MET P08581 Hepatocyte growth factor receptor chr7 GO:0030182 Census, Compendium Yes 226 0.163 62 15 0.242 19
MTPN MTPN P58546 Myotrophin chr7 GO:0030182 Not Cancer Driver No 11 0.093 11 3 0.273 0
MYEF2 MYEF2 Q9P2K5 Myelin expression factor 2 chr15 GO:0030182 Not Cancer Driver No 85 0.142 370 45 0.122 0
MYO6 MYO6 Q9UM54 Unconventional myosin-VI chr6 GO:0030182 Not Cancer Driver No 176 0.136 342 41 0.12 3
MYO7A MYO7A Q13402 Unconventional myosin-VIIa chr11 GO:0030182 Not Cancer Driver No 298 0.135 369 58 0.157 50
MYT1L MYT1L Q9UL68 Myelin transcription factor 1-like protein chr2 GO:0030182 Not Cancer Driver No 361 0.304 1090 337 0.309 0
NAPA NAPA P54920 Alpha-soluble NSF attachment protein chr19 GO:0030182 Not Cancer Driver No 33 0.112 11 0 0.0 0
NEUROD1 NEUROD1 Q13562 Neurogenic differentiation factor 1 chr2 GO:0030182 Not Cancer Driver No 84 0.236 202 52 0.257 2
NEUROD2 NEUROD2 Q15784 Neurogenic differentiation factor 2 chr17 GO:0030182 Not Cancer Driver No 26 0.068 210 14 0.067 2
NEUROD4 NEUROD4 Q9HD90 Neurogenic differentiation factor 4 chr12 GO:0030182 Not Cancer Driver No 123 0.372 236 83 0.352 0
NEUROD6 NEUROD6 Q96NK8 Neurogenic differentiation factor 6 chr7 GO:0030182 Not Cancer Driver No 101 0.3 186 63 0.339 0
NEUROG1 NEUROG1 Q92886 Neurogenin-1 chr5 GO:0030182 Not Cancer Driver No 27 0.114 178 18 0.101 0
NEUROG2 NEUROG2 Q9H2A3 Neurogenin-2 chr4 GO:0030182 Not Cancer Driver No 32 0.118 209 29 0.139 0
NEUROG3 NEUROG3 Q9Y4Z2 Neurogenin-3 chr10 GO:0030182 Not Cancer Driver No 53 0.248 156 34 0.218 2
NGRN NGRN Q9NPE2 Neugrin chr15 GO:0030182 Not Cancer Driver No 26 0.089 215 21 0.098 0
NIF3L1_ENST00000409357 NIF3L1 Q9GZT8 NIF3-like protein 1 chr2 GO:0030182 Not Cancer Driver No 55 0.146 43 3 0.07 0
NKX2-2 NKX2-2 O95096 Homeobox protein Nkx-2.2 chr20 GO:0030182 Not Cancer Driver No 84 0.308 206 65 0.316 0
NLGN4X_ENST00000381093 NLGN4X Q8N0W4 Neuroligin-4, X-linked chrX GO:0030182 Not Cancer Driver No 279 0.342 211 81 0.384 0
NOTO NOTO A8MTQ0 Homeobox protein notochord chr2 GO:0030182 Not Cancer Driver No 15 0.06 116 6 0.052 0
NOVA2 NOVA2 Q9UNW9 RNA-binding protein Nova-2 chr19 GO:0030182 Not Cancer Driver No 43 0.087 163 14 0.086 0
NR2E1_ENST00000368986 NR2E1 Q9Y466 Nuclear receptor subfamily 2 group E member 1 chr6 GO:0030182 Not Cancer Driver No 75 0.195 57 6 0.105 0
NR4A2_ENST00000409572 NR4A2 P43354 Nuclear receptor subfamily 4 group A member 2 chr2 GO:0030182 Not Cancer Driver No 110 0.184 261 38 0.146 0
NRBP2 NRBP2 Q9NSY0 Nuclear receptor-binding protein 2 chr8 GO:0030182 Not Cancer Driver No 30 0.06 110 5 0.045 0
NTF4 NTF4 P34130 Neurotrophin-4 chr19 GO:0030182 Not Cancer Driver No 21 0.1 56 4 0.071 0
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 GO:0030182 Census, Compendium Yes 168 0.211 57 8 0.14 25
NTRK2_ENST00000323115 NTRK2 Q16620 BDNF/NT-3 growth factors receptor chr9 GO:0030182 Not Cancer Driver No 155 0.189 117 18 0.154 1
OLIG1 OLIG1 Q8TAK6 Oligodendrocyte transcription factor 1 chr21 GO:0030182 Not Cancer Driver No 6 0.022 130 1 0.008 0
OLIG2_ENST00000382357 OLIG2 Q13516 Oligodendrocyte transcription factor 2 chr21 GO:0030182 Census Yes 37 0.115 256 37 0.145 0
OLIG3 OLIG3 Q7RTU3 Oligodendrocyte transcription factor 3 chr6 GO:0030182 Not Cancer Driver No 50 0.184 186 39 0.21 0
OPHN1 OPHN1 O60890 Oligophrenin-1 chrX GO:0030182 Not Cancer Driver No 122 0.152 302 42 0.139 0
OTP OTP Q5XKR4 Homeobox protein orthopedia chr5 GO:0030182 Not Cancer Driver No 36 0.111 278 29 0.104 0
OTX2_ENST00000408990 OTX2 P32243 Homeobox protein OTX2 chr14 GO:0030182 Not Cancer Driver No 76 0.263 165 41 0.248 6
PAFAH1B1 PAFAH1B1 P43034 Platelet-activating factor acetylhydrolase IB subunit beta chr17 GO:0030182 Not Cancer Driver No 42 0.102 82 11 0.134 7
PCSK9 PCSK9 Q8NBP7 Proprotein convertase subtilisin/kexin type 9 chr1 GO:0030182 Not Cancer Driver No 86 0.124 148 27 0.182 9
PEX5_ENST00000420616 PEX5 P50542 Peroxisomal targeting signal 1 receptor chr12 GO:0030182 Not Cancer Driver No 73 0.114 321 36 0.112 2
PHOX2A PHOX2A O14813 Paired mesoderm homeobox protein 2A chr11 GO:0030182 Not Cancer Driver No 20 0.07 172 12 0.07 1
PHOX2B PHOX2B Q99453 Paired mesoderm homeobox protein 2B chr4 GO:0030182 Census Yes 59 0.188 219 44 0.201 2
PIGT PIGT Q969N2 GPI transamidase component PIG-T chr20 GO:0030182 Not Cancer Driver No 51 0.088 36 6 0.167 1
PIN1 PIN1 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 chr19 GO:0030182 Not Cancer Driver No 17 0.104 115 12 0.104 0
PITX2_ENST00000354925 PITX2 Q99697 Pituitary homeobox 2 chr4 GO:0030182 Not Cancer Driver No 74 0.233 185 43 0.232 13
PITX3_ENST00000539804 PITX3 O75364 Pituitary homeobox 3 chr10 GO:0030182 Not Cancer Driver No 24 0.079 155 12 0.077 1
POU3F2 POU3F2 P20265 POU domain, class 3, transcription factor 2 chr6 GO:0030182 Not Cancer Driver No 52 0.117 361 36 0.1 0
POU4F2 POU4F2 Q12837 POU domain, class 4, transcription factor 2 chr4 GO:0030182 Not Cancer Driver No 130 0.318 308 87 0.282 0
POU4F3 POU4F3 Q15319 POU domain, class 4, transcription factor 3 chr5 GO:0030182 Not Cancer Driver No 62 0.183 198 39 0.197 10
PPP1CC_ENST00000335007 PPP1CC P36873 Serine/threonine-protein phosphatase PP1-gamma catalytic subunit chr12 GO:0030182 Not Cancer Driver No 26 0.08 23 4 0.174 0
PROM1 PROM1 O43490 Prominin-1 chr4 GO:0030182 Not Cancer Driver No 94 0.109 76 9 0.118 3
PROX1 PROX1 Q92786 Prospero homeobox protein 1 chr1 GO:0030182 Not Cancer Driver No 182 0.247 537 141 0.263 0
PSEN1 PSEN1 P49768 Presenilin-1 chr14 GO:0030182 Not Cancer Driver No 61 0.131 134 21 0.157 96
PTCH1 PTCH1 Q13635 Protein patched homolog 1 chr9 GO:0030182 Census, Compendium Yes 243 0.168 382 67 0.175 18
PTF1A PTF1A Q7RTS3 Pancreas transcription factor 1 subunit alpha chr10 GO:0030182 Not Cancer Driver No 35 0.107 231 31 0.134 0
PTPRD PTPRD P23468 Receptor-type tyrosine-protein phosphatase delta chr9 GO:0030182 Census, Compendium Yes 577 0.302 747 219 0.293 0
RNF112 RNF112 Q9ULX5 RING finger protein 112 chr17 GO:0030182 Not Cancer Driver No 86 0.136 168 26 0.155 0
ROM1 ROM1 Q03395 Rod outer segment membrane protein 1 chr11 GO:0030182 Not Cancer Driver No 41 0.117 26 4 0.154 0
RORA_ENST00000335670 RORA P35398 Nuclear receptor ROR-alpha chr15 GO:0030182 Not Cancer Driver No 57 0.109 182 17 0.093 4
RORB_ENST00000396204 RORB Q92753 Nuclear receptor ROR-beta chr9 GO:0030182 Not Cancer Driver No 107 0.228 87 22 0.253 1
RSPO2 RSPO2 Q6UXX9 R-spondin-2 chr8 GO:0030182 Census Yes 96 0.395 41 10 0.244 1
RUNX1_ENST00000344691 RUNX1 Q01196 Runt-related transcription factor 1 chr21 GO:0030182 Census, Compendium Yes 81 0.179 360 58 0.161 2
RUNX2_ENST00000647337 RUNX2 Q13950 Runt-related transcription factor 2 chr6 GO:0030182 Not Cancer Driver No 83 0.159 447 73 0.163 47
RUNX3_ENST00000308873 RUNX3 Q13761 Runt-related transcription factor 3 chr1 GO:0030182 Not Cancer Driver No 59 0.142 331 45 0.136 0
RXRG RXRG P48443 Retinoic acid receptor RXR-gamma chr1 GO:0030182 Not Cancer Driver No 103 0.222 161 41 0.255 0
RYK_ENST00000623711 RYK P34925 Tyrosine-protein kinase RYK chr3 GO:0030182 Not Cancer Driver No 55 0.091 85 4 0.047 0
S1PR1 S1PR1 P21453 Sphingosine 1-phosphate receptor 1 chr1 GO:0030182 Not Cancer Driver No 86 0.225 29 6 0.207 0
SALL1 SALL1 Q9NSC2 Sal-like protein 1 chr16 GO:0030182 Not Cancer Driver No 454 0.343 949 334 0.352 0
SCYL1 SCYL1 Q96KG9 N-terminal kinase-like protein chr11 GO:0030182 Not Cancer Driver No 85 0.105 312 32 0.103 0
SCYL3_ENST00000367770 SCYL3 Q8IZE3 Protein-associating with the carboxyl-terminal domain of ezrin chr1 GO:0030182 Not Cancer Driver No 81 0.109 249 28 0.112 0
SDK2 SDK2 Q58EX2 Protein sidekick-2 chr17 GO:0030182 Not Cancer Driver No 330 0.152 850 131 0.154 0
SFRP1 SFRP1 Q8N474 Secreted frizzled-related protein 1 chr8 GO:0030182 Not Cancer Driver No 40 0.127 39 7 0.179 0
SHH SHH Q15465 Sonic hedgehog protein chr7 GO:0030182 Not Cancer Driver No 56 0.121 139 14 0.101 81
SIN3A_ENST00000360439 SIN3A Q96ST3 Paired amphipathic helix protein Sin3a chr15 GO:0030182 Compendium Yes 172 0.135 617 73 0.118 0
SLC25A46 SLC25A46 Q96AG3 Mitochondrial outer membrane protein SLC25A46 chr5 GO:0030182 Not Cancer Driver No 37 0.089 96 2 0.021 4
SMARCA1_ENST00000371122 SMARCA1 P28370 Probable global transcription activator SNF2L1 chrX GO:0030182 Compendium Yes 143 0.136 309 41 0.133 0
SNPH_ENST00000381873 SNPH O15079 Syntaphilin chr20 GO:0030182 Not Cancer Driver No 79 0.16 406 71 0.175 0
SOX11 SOX11 P35716 Transcription factor SOX-11 chr2 GO:0030182 Not Cancer Driver No 61 0.138 368 53 0.144 2
SOX4 SOX4 Q06945 Transcription factor SOX-4 chr6 GO:0030182 Not Cancer Driver No 28 0.059 400 24 0.06 4
SOX8 SOX8 P57073 Transcription factor SOX-8 chr16 GO:0030182 Not Cancer Driver No 43 0.096 403 39 0.097 0
SOX9 SOX9 P48436 Transcription factor SOX-9 chr17 GO:0030182 Compendium Yes 86 0.169 495 82 0.166 18
SPINK5_ENST00000256084 SPINK5 Q9NQ38 Serine protease inhibitor Kazal-type 5 chr5 GO:0030182 Not Cancer Driver No 168 0.158 590 102 0.173 0
STAT3 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 GO:0030182 Census, Compendium Yes 110 0.143 152 15 0.099 19
STRAP STRAP Q9Y3F4 Serine-threonine kinase receptor-associated protein chr12 GO:0030182 Not Cancer Driver No 44 0.126 40 5 0.125 0
TAL1 TAL1 P17542 T-cell acute lymphocytic leukemia protein 1 chr1 GO:0030182 Census Yes 54 0.163 305 53 0.174 0
TBX20 TBX20 Q9UMR3 T-box transcription factor TBX20 chr7 GO:0030182 Not Cancer Driver No 117 0.262 201 54 0.269 2
TCTN1_ENST00000551590 TCTN1 Q2MV58 Tectonic-1 chr12 GO:0030182 Not Cancer Driver No 63 0.107 47 6 0.128 0
TENT2_ENST00000428308 TENT2 Q6PIY7 Poly(A) RNA polymerase GLD2 chr5 GO:0030182 Not Cancer Driver No 65 0.134 75 15 0.2 0
TOX TOX O94900 Thymocyte selection-associated high mobility group box protein TOX chr8 GO:0030182 Not Cancer Driver No 112 0.213 494 108 0.219 0
TRAPPC9_ENST00000438773 TRAPPC9 Q96Q05 Trafficking protein particle complex subunit 9 chr8 GO:0030182 Not Cancer Driver No 155 0.135 132 21 0.159 0
TRPC5 TRPC5 Q9UL62 Short transient receptor potential channel 5 chrX GO:0030182 Not Cancer Driver No 255 0.262 148 32 0.216 0
TTC21B TTC21B Q7Z4L5 Tetratricopeptide repeat protein 21B chr2 GO:0030182 Not Cancer Driver No 176 0.134 73 14 0.192 11
TTC8_ENST00000338104 TTC8 Q8TAM2 Tetratricopeptide repeat protein 8 chr14 GO:0030182 Not Cancer Driver No 74 0.137 98 12 0.122 0
TTLL1 TTLL1 O95922 Polyglutamylase complex subunit TTLL1 chr22 GO:0030182 Not Cancer Driver No 69 0.163 48 9 0.188 0
UNC5D UNC5D Q6UXZ4 Netrin receptor UNC5D chr8 GO:0030182 Not Cancer Driver No 292 0.306 194 44 0.227 0
UNCX UNCX A6NJT0 Homeobox protein unc-4 homolog chr7 GO:0030182 Not Cancer Driver No 28 0.053 410 17 0.041 0
USH1C_ENST00000318024 USH1C Q9Y6N9 Harmonin chr11 GO:0030182 Not Cancer Driver No 118 0.214 153 45 0.294 0
USH2A USH2A O75445 Usherin chr1 GO:0030182 Not Cancer Driver No 1503 0.289 773 235 0.304 70
VAX1 VAX1 Q5SQQ9 Ventral anterior homeobox 1 chr10 GO:0030182 Not Cancer Driver No 36 0.108 234 25 0.107 1
VAX2 VAX2 Q9UIW0 Ventral anterior homeobox 2 chr2 GO:0030182 Not Cancer Driver No 34 0.117 210 22 0.105 0
VCAM1 VCAM1 P19320 Vascular cell adhesion protein 1 chr1 GO:0030182 Not Cancer Driver No 188 0.254 110 28 0.255 0
VEGFA_ENST00000523873 VEGFA P15692 Vascular endothelial growth factor A chr6 GO:0030182 Not Cancer Driver No 27 0.116 41 7 0.171 0
VEGFD VEGFD O43915 Vascular endothelial growth factor D chrX GO:0030182 Not Cancer Driver No 59 0.167 33 6 0.182 0
VSX1 VSX1 Q9NZR4 Visual system homeobox 1 chr20 GO:0030182 Not Cancer Driver No 28 0.077 268 23 0.086 4
VXN VXN Q8TAG6 Vexin chr8 GO:0030182 Not Cancer Driver No 39 0.188 183 36 0.197 0
WNT1 WNT1 P04628 Proto-oncogene Wnt-1 chr12 GO:0030182 Not Cancer Driver No 29 0.078 25 0 0.0 8
WNT10A WNT10A Q9GZT5 Protein Wnt-10a chr2 GO:0030182 Not Cancer Driver No 39 0.094 123 10 0.081 9
WNT10B WNT10B O00744 Protein Wnt-10b chr12 GO:0030182 Not Cancer Driver No 56 0.144 84 16 0.19 2
WNT11 WNT11 O96014 Protein Wnt-11 chr11 GO:0030182 Not Cancer Driver No 55 0.155 59 4 0.068 0
WNT16 WNT16 Q9UBV4 Protein Wnt-16 chr7 GO:0030182 Not Cancer Driver No 59 0.162 28 9 0.321 0
WNT2 WNT2 P09544 Protein Wnt-2 chr7 GO:0030182 Not Cancer Driver No 85 0.236 11 3 0.273 0
WNT2B WNT2B Q93097 Protein Wnt-2b chr1 GO:0030182 Not Cancer Driver No 72 0.184 27 3 0.111 0
WNT3 WNT3 P56703 Proto-oncogene Wnt-3 chr17 GO:0030182 Not Cancer Driver No 56 0.158 34 7 0.206 0
WNT3A WNT3A P56704 Protein Wnt-3a chr1 GO:0030182 Not Cancer Driver No 77 0.219 37 5 0.135 0
WNT4 WNT4 P56705 Protein Wnt-4 chr1 GO:0030182 Not Cancer Driver No 30 0.085 39 4 0.103 4
WNT5A_ENST00000474267 WNT5A P41221 Protein Wnt-5a chr3 GO:0030182 Not Cancer Driver No 66 0.174 0 0 0.0 2
WNT5B_ENST00000310594 WNT5B Q9H1J7 Protein Wnt-5b chr12 GO:0030182 Not Cancer Driver No 60 0.167 23 4 0.174 0
WNT6 WNT6 Q9Y6F9 Protein Wnt-6 chr2 GO:0030182 Not Cancer Driver No 30 0.082 84 9 0.107 0
WNT7A WNT7A O00755 Protein Wnt-7a chr3 GO:0030182 Not Cancer Driver No 93 0.266 18 9 0.5 4
WNT7B WNT7B P56706 Protein Wnt-7b chr22 GO:0030182 Not Cancer Driver No 55 0.158 11 1 0.091 0
WNT8A_ENST00000398754 WNT8A Q9H1J5 Protein Wnt-8a chr5 GO:0030182 Not Cancer Driver No 50 0.142 3 0 0.0 0
WNT8B WNT8B Q93098 Protein Wnt-8b chr10 GO:0030182 Not Cancer Driver No 50 0.142 27 5 0.185 0
WNT9A WNT9A O14904 Protein Wnt-9a chr1 GO:0030182 Not Cancer Driver No 74 0.203 44 11 0.25 0
WNT9B WNT9B O14905 Protein Wnt-9b chr17 GO:0030182 Not Cancer Driver No 47 0.132 11 4 0.364 0
XRN2 XRN2 Q9H0D6 5'-3' exoribonuclease 2 chr20 GO:0030182 Not Cancer Driver No 129 0.136 427 63 0.148 0
ZC4H2 ZC4H2 Q9NQZ6 Zinc finger C4H2 domain-containing protein chrX GO:0030182 Not Cancer Driver No 60 0.268 136 43 0.316 13
ZHX2 ZHX2 Q9Y6X8 Zinc fingers and homeoboxes protein 2 chr8 GO:0030182 Not Cancer Driver No 151 0.18 593 103 0.174 0
ZNF335 ZNF335 Q9H4Z2 Zinc finger protein 335 chr20 GO:0030182 Not Cancer Driver No 185 0.138 942 133 0.141 1
ZSWIM6 ZSWIM6 Q9HCJ5 Zinc finger SWIM domain-containing protein 6 chr5 GO:0030182 Not Cancer Driver No 64 0.053 244 7 0.029 1