Total number of protein in "GO:0030136" GO term: 91
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AAK1 | AAK1 | Q2M2I8 | AP2-associated protein kinase 1 | chr2 | GO:0030136 | Not Cancer Driver | No | 109 | 0.113 | 654 | 70 | 0.107 | 0 |
| ABCB4 | ABCB4 | P21439 | Phosphatidylcholine translocator ABCB4 | chr7 | GO:0030136 | Not Cancer Driver | No | 243 | 0.189 | 74 | 14 | 0.189 | 72 |
| ADAM10 | ADAM10 | O14672 | Disintegrin and metalloproteinase domain-containing protein 10 | chr15 | GO:0030136 | Not Cancer Driver | No | 88 | 0.118 | 156 | 20 | 0.128 | 4 |
| AP1G1_ENST00000569748 | AP1G1 | O43747 | AP-1 complex subunit gamma-1 | chr16 | GO:0030136 | Not Cancer Driver | No | 111 | 0.135 | 144 | 22 | 0.153 | 0 |
| AP1M1_ENST00000291439 | AP1M1 | Q9BXS5 | AP-1 complex subunit mu-1 | chr19 | GO:0030136 | Not Cancer Driver | No | 64 | 0.151 | 38 | 12 | 0.316 | 0 |
| AP1M2_ENST00000250244 | AP1M2 | Q9Y6Q5 | AP-1 complex subunit mu-2 | chr19 | GO:0030136 | Not Cancer Driver | No | 52 | 0.123 | 15 | 1 | 0.067 | 0 |
| AP2A1 | AP2A1 | O95782 | AP-2 complex subunit alpha-1 | chr19 | GO:0030136 | Not Cancer Driver | No | 95 | 0.097 | 188 | 12 | 0.064 | 0 |
| AP2A2_ENST00000448903 | AP2A2 | O94973 | AP-2 complex subunit alpha-2 | chr11 | GO:0030136 | Not Cancer Driver | No | 100 | 0.106 | 145 | 12 | 0.083 | 0 |
| AP2B1_ENST00000621914 | AP2B1 | P63010 | AP-2 complex subunit beta | chr17 | GO:0030136 | Not Cancer Driver | No | 85 | 0.091 | 95 | 12 | 0.126 | 0 |
| AP2M1_ENST00000292807 | AP2M1 | Q96CW1 | AP-2 complex subunit mu | chr3 | GO:0030136 | Not Cancer Driver | No | 55 | 0.126 | 41 | 9 | 0.22 | 1 |
| AP2S1_ENST00000263270 | AP2S1 | P53680 | AP-2 complex subunit sigma | chr19 | GO:0030136 | Not Cancer Driver | No | 4 | 0.028 | 0 | 0 | 0.0 | 3 |
| ASTN1 | ASTN1 | O14525 | Astrotactin-1 | chr1 | GO:0030136 | Not Cancer Driver | No | 466 | 0.358 | 285 | 114 | 0.4 | 0 |
| ASTN2_ENST00000313400 | ASTN2 | O75129 | Astrotactin-2 | chr9 | GO:0030136 | Not Cancer Driver | No | 347 | 0.259 | 283 | 96 | 0.339 | 0 |
| BCAP31_ENST00000345046 | BCAP31 | P51572 | B-cell receptor-associated protein 31 | chrX | GO:0030136 | Not Cancer Driver | No | 37 | 0.15 | 104 | 14 | 0.135 | 0 |
| CEMIP_ENST00000356249 | CEMIP | Q8WUJ3 | Cell migration-inducing and hyaluronan-binding protein | chr15 | GO:0030136 | Not Cancer Driver | No | 207 | 0.152 | 105 | 10 | 0.095 | 0 |
| CLTA | CLTA | P09496 | Clathrin light chain A | chr9 | GO:0030136 | Not Cancer Driver | No | 20 | 0.081 | 192 | 12 | 0.062 | 0 |
| CLTB | CLTB | P09497 | Clathrin light chain B | chr5 | GO:0030136 | Not Cancer Driver | No | 33 | 0.144 | 193 | 28 | 0.145 | 0 |
| CLTCL1 | CLTCL1 | P53675 | Clathrin heavy chain 2 | chr22 | GO:0030136 | Census, Compendium | Yes | 210 | 0.128 | 10 | 1 | 0.1 | 0 |
| CLTC_ENST00000269122 | CLTC | Q00610 | Clathrin heavy chain 1 | chr17 | GO:0030136 | Census, Compendium | Yes | 190 | 0.113 | 71 | 6 | 0.085 | 1 |
| CLVS1 | CLVS1 | Q8IUQ0 | Clavesin-1 | chr8 | GO:0030136 | Not Cancer Driver | No | 121 | 0.342 | 68 | 16 | 0.235 | 0 |
| CLVS2 | CLVS2 | Q5SYC1 | Clavesin-2 | chr6 | GO:0030136 | Not Cancer Driver | No | 123 | 0.376 | 79 | 30 | 0.38 | 0 |
| CPNE6_ENST00000397016 | CPNE6 | O95741 | Copine-6 | chr14 | GO:0030136 | Not Cancer Driver | No | 85 | 0.153 | 111 | 22 | 0.198 | 0 |
| CRACR2A | CRACR2A | Q9BSW2 | EF-hand calcium-binding domain-containing protein 4B | chr12 | GO:0030136 | Not Cancer Driver | No | 88 | 0.12 | 436 | 60 | 0.138 | 0 |
| CTLA4 | CTLA4 | P16410 | Cytotoxic T-lymphocyte protein 4 | chr2 | GO:0030136 | Not Cancer Driver | No | 37 | 0.166 | 3 | 0 | 0.0 | 1 |
| DAB2 | DAB2 | P98082 | Disabled homolog 2 | chr5 | GO:0030136 | Not Cancer Driver | No | 144 | 0.187 | 680 | 125 | 0.184 | 0 |
| DENND1A | DENND1A | Q8TEH3 | DENN domain-containing protein 1A | chr9 | GO:0030136 | Not Cancer Driver | No | 117 | 0.116 | 589 | 76 | 0.129 | 0 |
| DENND1B | DENND1B | Q6P3S1 | DENN domain-containing protein 1B | chr1 | GO:0030136 | Not Cancer Driver | No | 69 | 0.089 | 299 | 19 | 0.064 | 0 |
| DENND1C | DENND1C | Q8IV53 | DENN domain-containing protein 1C | chr19 | GO:0030136 | Not Cancer Driver | No | 102 | 0.127 | 369 | 54 | 0.146 | 0 |
| DNM2_ENST00000355667 | DNM2 | P50570 | Dynamin-2 | chr19 | GO:0030136 | Census | Yes | 138 | 0.159 | 270 | 43 | 0.159 | 22 |
| DVL1 | DVL1 | O14640 | Segment polarity protein dishevelled homolog DVL-1 | chr1 | GO:0030136 | Not Cancer Driver | No | 73 | 0.105 | 434 | 38 | 0.088 | 0 |
| DVL2 | DVL2 | O14641 | Segment polarity protein dishevelled homolog DVL-2 | chr17 | GO:0030136 | Not Cancer Driver | No | 96 | 0.13 | 514 | 64 | 0.125 | 0 |
| ECE1 | ECE1 | P42892 | Endothelin-converting enzyme 1 | chr1 | GO:0030136 | Not Cancer Driver | No | 118 | 0.153 | 99 | 26 | 0.263 | 1 |
| EDN1 | EDN1 | P05305 | Endothelin-1 | chr6 | GO:0030136 | Not Cancer Driver | No | 37 | 0.175 | 97 | 20 | 0.206 | 3 |
| EPN3 | EPN3 | Q9H201 | Epsin-3 | chr17 | GO:0030136 | Not Cancer Driver | No | 80 | 0.127 | 522 | 72 | 0.138 | 0 |
| FCHO1_ENST00000600676 | FCHO1 | O14526 | F-BAR domain only protein 1 | chr19 | GO:0030136 | Not Cancer Driver | No | 127 | 0.143 | 533 | 69 | 0.129 | 2 |
| FCHO2 | FCHO2 | Q0JRZ9 | F-BAR domain only protein 2 | chr5 | GO:0030136 | Not Cancer Driver | No | 79 | 0.098 | 373 | 45 | 0.121 | 0 |
| FOLR1_ENST00000393681 | FOLR1 | P15328 | Folate receptor alpha | chr11 | GO:0030136 | Not Cancer Driver | No | 41 | 0.16 | 13 | 3 | 0.231 | 0 |
| GGA2 | GGA2 | Q9UJY4 | ADP-ribosylation factor-binding protein GGA2 | chr16 | GO:0030136 | Not Cancer Driver | No | 84 | 0.137 | 240 | 37 | 0.154 | 0 |
| GPR107_ENST00000610997 | GPR107 | Q5VW38 | Protein GPR107 | chr9 | GO:0030136 | Not Cancer Driver | No | 54 | 0.09 | 69 | 5 | 0.072 | 0 |
| HAX1 | HAX1 | O00165 | HCLS1-associated protein X-1 | chr1 | GO:0030136 | Not Cancer Driver | No | 44 | 0.158 | 219 | 32 | 0.146 | 2 |
| HEATR5B | HEATR5B | Q9P2D3 | HEAT repeat-containing protein 5B | chr2 | GO:0030136 | Not Cancer Driver | No | 250 | 0.121 | 163 | 14 | 0.086 | 0 |
| HIP1 | HIP1 | O00291 | Huntingtin-interacting protein 1 | chr7 | GO:0030136 | Census, Compendium | Yes | 137 | 0.132 | 510 | 70 | 0.137 | 0 |
| HIP1R | HIP1R | O75146 | Huntingtin-interacting protein 1-related protein | chr12 | GO:0030136 | Not Cancer Driver | No | 94 | 0.088 | 524 | 34 | 0.065 | 0 |
| INPP5F | INPP5F | Q9Y2H2 | Phosphatidylinositide phosphatase SAC2 | chr10 | GO:0030136 | Not Cancer Driver | No | 138 | 0.122 | 394 | 45 | 0.114 | 0 |
| LMBRD1 | LMBRD1 | Q9NUN5 | Lysosomal cobalamin transport escort protein LMBD1 | chr6 | GO:0030136 | Not Cancer Driver | No | 90 | 0.167 | 31 | 3 | 0.097 | 0 |
| MALL | MALL | Q13021 | MAL-like protein | chr2 | GO:0030136 | Not Cancer Driver | No | 20 | 0.131 | 0 | 0 | 0.0 | 0 |
| MLC1 | MLC1 | Q15049 | Membrane protein MLC1 | chr22 | GO:0030136 | Not Cancer Driver | No | 53 | 0.141 | 35 | 7 | 0.2 | 15 |
| MYO1E | MYO1E | Q12965 | Unconventional myosin-Ie | chr15 | GO:0030136 | Not Cancer Driver | No | 137 | 0.124 | 229 | 14 | 0.061 | 1 |
| MYO6 | MYO6 | Q9UM54 | Unconventional myosin-VI | chr6 | GO:0030136 | Not Cancer Driver | No | 176 | 0.136 | 342 | 41 | 0.12 | 3 |
| NUMB_ENST00000355058 | NUMB | P49757 | Protein numb homolog | chr14 | GO:0030136 | Not Cancer Driver | No | 70 | 0.108 | 490 | 58 | 0.118 | 0 |
| OCRL | OCRL | Q01968 | Inositol polyphosphate 5-phosphatase OCRL | chrX | GO:0030136 | Not Cancer Driver | No | 151 | 0.168 | 126 | 24 | 0.19 | 41 |
| PANK1 | PANK1 | Q8TE04 | Pantothenate kinase 1 | chr10 | GO:0030136 | Not Cancer Driver | No | 62 | 0.104 | 248 | 17 | 0.069 | 0 |
| PHETA1_ENST00000547838 | PHETA1 | Q8N4B1 | Sesquipedalian-1 | chr12 | GO:0030136 | Not Cancer Driver | No | 19 | 0.076 | 115 | 3 | 0.026 | 0 |
| PHETA2 | PHETA2 | Q6ICB4 | Sesquipedalian-2 | chr22 | GO:0030136 | Not Cancer Driver | No | 22 | 0.085 | 76 | 6 | 0.079 | 0 |
| PICALM | PICALM | Q13492 | Phosphatidylinositol-binding clathrin assembly protein | chr11 | GO:0030136 | Census | Yes | 89 | 0.137 | 320 | 42 | 0.131 | 0 |
| PIK3C2A | PIK3C2A | O00443 | Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha | chr11 | GO:0030136 | Not Cancer Driver | No | 187 | 0.111 | 350 | 43 | 0.123 | 0 |
| RAB27A_ENST00000336787 | RAB27A | P51159 | Ras-related protein Rab-27A | chr15 | GO:0030136 | Not Cancer Driver | No | 25 | 0.113 | 15 | 4 | 0.267 | 3 |
| RAB35 | RAB35 | Q15286 | Ras-related protein Rab-35 | chr12 | GO:0030136 | Not Cancer Driver | No | 25 | 0.124 | 25 | 2 | 0.08 | 0 |
| RGS19_ENST00000332298 | RGS19 | P49795 | Regulator of G-protein signaling 19 | chr20 | GO:0030136 | Not Cancer Driver | No | 27 | 0.124 | 71 | 8 | 0.113 | 0 |
| SCAMP1 | SCAMP1 | O15126 | Secretory carrier-associated membrane protein 1 | chr5 | GO:0030136 | Not Cancer Driver | No | 29 | 0.086 | 117 | 14 | 0.12 | 0 |
| SCYL2_ENST00000360820 | SCYL2 | Q6P3W7 | SCY1-like protein 2 | chr12 | GO:0030136 | Not Cancer Driver | No | 103 | 0.111 | 328 | 29 | 0.088 | 0 |
| SFTA3 | SFTA3 | P0C7M3 | Surfactant-associated protein 3 | chr14 | GO:0030136 | Not Cancer Driver | No | 22 | 0.234 | 13 | 2 | 0.154 | 0 |
| SFTPA1_ENST00000398636 | SFTPA1 | Q8IWL2 | Pulmonary surfactant-associated protein A1 | chr10 | GO:0030136 | Not Cancer Driver | No | 41 | 0.165 | 171 | 33 | 0.193 | 3 |
| SFTPA2 | SFTPA2 | Q8IWL1 | Pulmonary surfactant-associated protein A2 | chr10 | GO:0030136 | Not Cancer Driver | No | 53 | 0.214 | 174 | 43 | 0.247 | 7 |
| SFTPB_ENST00000519937 | SFTPB | P07988 | Pulmonary surfactant-associated protein B | chr2 | GO:0030136 | Not Cancer Driver | No | 57 | 0.15 | 37 | 6 | 0.162 | 1 |
| SFTPC | SFTPC | P11686 | Pulmonary surfactant-associated protein C | chr8 | GO:0030136 | Not Cancer Driver | No | 21 | 0.107 | 19 | 2 | 0.105 | 5 |
| SFTPD | SFTPD | P35247 | Pulmonary surfactant-associated protein D | chr10 | GO:0030136 | Not Cancer Driver | No | 66 | 0.176 | 274 | 53 | 0.193 | 0 |
| SGIP1 | SGIP1 | Q9BQI5 | SH3-containing GRB2-like protein 3-interacting protein 1 | chr1 | GO:0030136 | Not Cancer Driver | No | 210 | 0.254 | 559 | 152 | 0.272 | 0 |
| SH3BP4_ENST00000392011 | SH3BP4 | Q9P0V3 | SH3 domain-binding protein 4 | chr2 | GO:0030136 | Not Cancer Driver | No | 143 | 0.148 | 241 | 43 | 0.178 | 0 |
| SLC2A4 | SLC2A4 | P14672 | Solute carrier family 2, facilitated glucose transporter member 4 | chr17 | GO:0030136 | Not Cancer Driver | No | 71 | 0.139 | 43 | 8 | 0.186 | 1 |
| SNAP91_ENST00000369694 | SNAP91 | O60641 | Clathrin coat assembly protein AP180 | chr6 | GO:0030136 | Not Cancer Driver | No | 203 | 0.224 | 636 | 118 | 0.186 | 0 |
| SNX18 | SNX18 | Q96RF0 | Sorting nexin-18 | chr5 | GO:0030136 | Not Cancer Driver | No | 54 | 0.086 | 236 | 7 | 0.03 | 0 |
| SNX3 | SNX3 | O60493 | Sorting nexin-3 | chr6 | GO:0030136 | Not Cancer Driver | No | 21 | 0.13 | 37 | 4 | 0.108 | 0 |
| SNX9 | SNX9 | Q9Y5X1 | Sorting nexin-9 | chr6 | GO:0030136 | Not Cancer Driver | No | 71 | 0.119 | 231 | 23 | 0.1 | 0 |
| SORT1 | SORT1 | Q99523 | Sortilin | chr1 | GO:0030136 | Not Cancer Driver | No | 69 | 0.083 | 110 | 2 | 0.018 | 0 |
| STON1 | STON1 | Q9Y6Q2 | Stonin-1 | chr2 | GO:0030136 | Not Cancer Driver | No | 139 | 0.189 | 215 | 45 | 0.209 | 0 |
| STON2_ENST00000267540 | STON2 | Q8WXE9 | Stonin-2 | chr14 | GO:0030136 | Not Cancer Driver | No | 153 | 0.169 | 449 | 77 | 0.171 | 0 |
| STX6 | STX6 | O43752 | Syntaxin-6 | chr1 | GO:0030136 | Not Cancer Driver | No | 33 | 0.129 | 78 | 11 | 0.141 | 0 |
| TNK2_ENST00000333602 | TNK2 | Q07912 | Activated CDC42 kinase 1 | chr3 | GO:0030136 | Not Cancer Driver | No | 137 | 0.132 | 593 | 81 | 0.137 | 0 |
| UNC13D | UNC13D | Q70J99 | Protein unc-13 homolog D | chr17 | GO:0030136 | Not Cancer Driver | No | 120 | 0.11 | 248 | 30 | 0.121 | 0 |
| VAMP2_ENST00000316509 | VAMP2 | P63027 | Vesicle-associated membrane protein 2 | chr17 | GO:0030136 | Not Cancer Driver | No | 7 | 0.06 | 47 | 4 | 0.085 | 3 |
| VAMP3 | VAMP3 | Q15836 | Vesicle-associated membrane protein 3 | chr1 | GO:0030136 | Not Cancer Driver | No | 11 | 0.11 | 17 | 1 | 0.059 | 0 |
| VPS11 | VPS11 | Q9H270 | Vacuolar protein sorting-associated protein 11 homolog | chr11 | GO:0030136 | Not Cancer Driver | No | 96 | 0.102 | 118 | 6 | 0.051 | 1 |
| VPS16 | VPS16 | Q9H269 | Vacuolar protein sorting-associated protein 16 homolog | chr20 | GO:0030136 | Not Cancer Driver | No | 104 | 0.124 | 34 | 5 | 0.147 | 1 |
| VPS18 | VPS18 | Q9P253 | Vacuolar protein sorting-associated protein 18 homolog | chr15 | GO:0030136 | Not Cancer Driver | No | 96 | 0.099 | 86 | 7 | 0.081 | 0 |
| VPS33A | VPS33A | Q96AX1 | Vacuolar protein sorting-associated protein 33A | chr12 | GO:0030136 | Not Cancer Driver | No | 73 | 0.122 | 46 | 8 | 0.174 | 1 |
| VPS33B | VPS33B | Q9H267 | Vacuolar protein sorting-associated protein 33B | chr15 | GO:0030136 | Not Cancer Driver | No | 54 | 0.088 | 17 | 0 | 0.0 | 2 |
| VPS41 | VPS41 | P49754 | Vacuolar protein sorting-associated protein 41 homolog | chr7 | GO:0030136 | Not Cancer Driver | No | 116 | 0.136 | 45 | 12 | 0.267 | 2 |
| VTI1A | VTI1A | Q96AJ9 | Vesicle transport through interaction with t-SNAREs homolog 1A | chr10 | GO:0030136 | Census | Yes | 21 | 0.097 | 138 | 13 | 0.094 | 0 |
| VWF | VWF | P04275 | von Willebrand factor | chr12 | GO:0030136 | Not Cancer Driver | No | 456 | 0.162 | 91 | 16 | 0.176 | 43 |
| WIPI1 | WIPI1 | Q5MNZ9 | WD repeat domain phosphoinositide-interacting protein 1 | chr17 | GO:0030136 | Not Cancer Driver | No | 45 | 0.101 | 113 | 9 | 0.08 | 0 |