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Total number of protein in "GO:0030099" GO term:  118

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ACTN1_ENST00000193403 ACTN1 P12814 Alpha-actinin-1 chr14 GO:0030099 Not Cancer Driver No 108 0.121 195 30 0.154 6
AP3B1 AP3B1 O00203 AP-3 complex subunit beta-1 chr5 GO:0030099 Not Cancer Driver No 126 0.115 316 31 0.098 1
BATF BATF Q16520 Basic leucine zipper transcriptional factor ATF-like chr14 GO:0030099 Not Cancer Driver No 28 0.224 119 25 0.21 0
BATF2 BATF2 Q8N1L9 Basic leucine zipper transcriptional factor ATF-like 2 chr11 GO:0030099 Not Cancer Driver No 28 0.102 202 19 0.094 0
BATF3 BATF3 Q9NR55 Basic leucine zipper transcriptional factor ATF-like 3 chr1 GO:0030099 Not Cancer Driver No 18 0.142 127 18 0.142 0
BMP4 BMP4 P12644 Bone morphogenetic protein 4 chr14 GO:0030099 Not Cancer Driver No 86 0.211 142 26 0.183 5
CAMK4_ENST00000512453 CAMK4 Q16566 Calcium/calmodulin-dependent protein kinase type IV chr5 GO:0030099 Not Cancer Driver No 101 0.214 127 30 0.236 0
CASP3 CASP3 P42574 Caspase-3 chr4 GO:0030099 Census Yes 32 0.116 62 5 0.081 0
CASP8_ENST00000432109 CASP8 Q14790 Caspase-8 chr2 GO:0030099 Census, Compendium Yes 142 0.296 106 12 0.113 1
CASP9 CASP9 P55211 Caspase-9 chr1 GO:0030099 Census Yes 49 0.118 71 7 0.099 0
CBFA2T3 CBFA2T3 O75081 Protein CBFA2T3 chr16 GO:0030099 Census, Compendium Yes 83 0.127 502 70 0.139 0
CBFB_ENST00000290858 CBFB Q13951 Core-binding factor subunit beta chr16 GO:0030099 Census, Compendium Yes 39 0.214 94 17 0.181 0
CCL19 CCL19 Q99731 C-C motif chemokine 19 chr9 GO:0030099 Not Cancer Driver No 10 0.102 7 0 0.0 0
CCR7 CCR7 P32248 C-C chemokine receptor type 7 chr17 GO:0030099 Census, Compendium Yes 50 0.132 0 0 0.0 0
CD4 CD4 P01730 T-cell surface glycoprotein CD4 chr12 GO:0030099 Not Cancer Driver No 69 0.151 56 11 0.196 0
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 GO:0030099 Not Cancer Driver No 39 0.204 23 2 0.087 1
CDK5RAP3_ENST00000338399 CDK5RAP3 Q96JB5 CDK5 regulatory subunit-associated protein 3 chr17 GO:0030099 Not Cancer Driver No 50 0.099 99 20 0.202 0
CDKN1C CDKN1C P49918 Cyclin-dependent kinase inhibitor 1C chr11 GO:0030099 Not Cancer Driver No 2 0.006 256 1 0.004 7
CDKN2B CDKN2B P42772 Cyclin-dependent kinase 4 inhibitor B chr9 GO:0030099 Not Cancer Driver No 15 0.109 67 3 0.045 0
CEBPA CEBPA P49715 CCAAT/enhancer-binding protein alpha chr19 GO:0030099 Census, Compendium Yes 12 0.034 342 12 0.035 1
CEBPE CEBPE Q15744 CCAAT/enhancer-binding protein epsilon chr14 GO:0030099 Not Cancer Driver No 56 0.199 257 53 0.206 0
CEBPG_ENST00000585933 CEBPG P53567 CCAAT/enhancer-binding protein gamma chr19 GO:0030099 Not Cancer Driver No 13 0.087 141 12 0.085 0
CIB1_ENST00000328649 CIB1 Q99828 Calcium and integrin-binding protein 1 chr15 GO:0030099 Not Cancer Driver No 24 0.126 6 1 0.167 0
CITED2_ENST00000367651 CITED2 Q99967 Cbp/p300-interacting transactivator 2 chr6 GO:0030099 Not Cancer Driver No 23 0.085 230 18 0.078 0
CLEC1B CLEC1B Q9P126 C-type lectin domain family 1 member B chr12 GO:0030099 Not Cancer Driver No 50 0.218 3 0 0.0 0
CLEC5A CLEC5A Q9NY25 C-type lectin domain family 5 member A chr7 GO:0030099 Not Cancer Driver No 46 0.245 0 0 0.0 0
CSF1R CSF1R P07333 Macrophage colony-stimulating factor 1 receptor chr5 GO:0030099 Census Yes 133 0.137 124 17 0.137 20
CSF1_ENST00000369802 CSF1 P09603 Macrophage colony-stimulating factor 1 chr1 GO:0030099 Not Cancer Driver No 69 0.125 339 46 0.136 0
CSF2 CSF2 P04141 Granulocyte-macrophage colony-stimulating factor chr5 GO:0030099 Not Cancer Driver No 11 0.076 34 3 0.088 0
CSF3 CSF3 P09919 Granulocyte colony-stimulating factor chr17 GO:0030099 Not Cancer Driver No 20 0.097 7 0 0.0 0
DCSTAMP DCSTAMP Q9H295 Dendritic cell-specific transmembrane protein chr8 GO:0030099 Compendium Yes 150 0.319 6 3 0.5 0
DHRS2_ENST00000250383 DHRS2 Q13268 Dehydrogenase/reductase SDR family member 2, mitochondrial chr14 GO:0030099 Not Cancer Driver No 47 0.168 0 0 0.0 0
DHRS7B DHRS7B Q6IAN0 Dehydrogenase/reductase SDR family member 7B chr17 GO:0030099 Not Cancer Driver No 37 0.114 17 0 0.0 0
EIF2AK1 EIF2AK1 Q9BQI3 Eukaryotic translation initiation factor 2-alpha kinase 1 chr7 GO:0030099 Not Cancer Driver No 87 0.138 238 29 0.122 0
EP300 EP300 Q09472 Histone acetyltransferase p300 chr22 GO:0030099 Census, Compendium Yes 334 0.138 1790 196 0.109 1
F2RL1 F2RL1 P55085 Proteinase-activated receptor 2 chr5 GO:0030099 Not Cancer Driver No 55 0.139 7 2 0.286 0
FASN FASN P49327 Fatty acid synthase chr17 GO:0030099 Not Cancer Driver No 291 0.116 309 42 0.136 0
GAB3_ENST00000369575 GAB3 Q8WWW8 GRB2-associated-binding protein 3 chrX GO:0030099 Not Cancer Driver No 86 0.147 390 60 0.154 0
GATA1 GATA1 P15976 Erythroid transcription factor chrX GO:0030099 Census, Compendium Yes 68 0.165 242 41 0.169 5
GATA3_ENST00000346208 GATA3 P23771 Trans-acting T-cell-specific transcription factor GATA-3 chr10 GO:0030099 Census, Compendium Yes 111 0.251 364 87 0.239 2
GBA_ENST00000368373 GBA P04062 Lysosomal acid glucosylceramidase chr1 GO:0030099 Not Cancer Driver No 74 0.138 38 5 0.132 171
HLA-DRB1 HLA-DRB1 P01911 HLA class II histocompatibility antigen, DRB1 beta chain chr6 GO:0030099 Not Cancer Driver No 48 0.18 12 1 0.083 0
HOXB7 HOXB7 P09629 Homeobox protein Hox-B7 chr17 GO:0030099 Not Cancer Driver No 25 0.115 84 10 0.119 0
ID2_ENST00000396290 ID2 Q02363 DNA-binding protein inhibitor ID-2 chr2 GO:0030099 Not Cancer Driver No 14 0.104 52 7 0.135 0
IFI16_ENST00000295809 IFI16 Q16666 Gamma-interferon-inducible protein 16 chr1 GO:0030099 Not Cancer Driver No 155 0.197 419 90 0.215 0
IFNG IFNG P01579 Interferon gamma chr12 GO:0030099 Not Cancer Driver No 51 0.307 23 6 0.261 0
IL11 IL11 P20809 Interleukin-11 chr19 GO:0030099 Not Cancer Driver No 19 0.095 69 8 0.116 0
IL15_ENST00000320650 IL15 P40933 Interleukin-15 chr4 GO:0030099 Not Cancer Driver No 25 0.154 6 1 0.167 0
IL25 IL25 Q9H293 Interleukin-25 chr14 GO:0030099 Not Cancer Driver No 30 0.169 50 8 0.16 0
IL31RA_ENST00000297015 IL31RA Q8NI17 Interleukin-31 receptor subunit alpha chr5 GO:0030099 Not Cancer Driver No 117 0.16 163 30 0.184 1
IL4 IL4 P05112 Interleukin-4 chr5 GO:0030099 Not Cancer Driver No 18 0.118 0 0 0.0 0
IRF4 IRF4 Q15306 Interferon regulatory factor 4 chr6 GO:0030099 Census, Compendium Yes 99 0.22 155 45 0.29 0
IRF8 IRF8 Q02556 Interferon regulatory factor 8 chr16 GO:0030099 Not Cancer Driver No 80 0.188 77 20 0.26 2
ITGB6_ENST00000409872 ITGB6 P18564 Integrin beta-6 chr2 GO:0030099 Not Cancer Driver No 120 0.152 26 4 0.154 3
ITGB8 ITGB8 P26012 Integrin beta-8 chr7 GO:0030099 Not Cancer Driver No 126 0.164 26 3 0.115 0
JAGN1 JAGN1 Q8N5M9 Protein jagunal homolog 1 chr3 GO:0030099 Not Cancer Driver No 21 0.115 12 2 0.167 5
JUN JUN P05412 Transcription factor Jun chr1 GO:0030099 Census Yes 35 0.106 281 25 0.089 0
KAT6A_ENST00000406337 KAT6A Q92794 Histone acetyltransferase KAT6A chr8 GO:0030099 Census, Compendium Yes 273 0.136 1420 193 0.136 0
KAT8_ENST00000219797 KAT8 Q9H7Z6 Histone acetyltransferase KAT8 chr16 GO:0030099 Not Cancer Driver No 66 0.144 156 20 0.128 4
KIT KIT P10721 Mast/stem cell growth factor receptor Kit chr4 GO:0030099 Census, Compendium Yes 226 0.232 83 33 0.398 21
L3MBTL3_ENST00000368136 L3MBTL3 Q96JM7 Lethal(3)malignant brain tumor-like protein 3 chr6 GO:0030099 Not Cancer Driver No 117 0.15 351 59 0.168 0
LBR_ENST00000272163 LBR Q14739 Delta(14)-sterol reductase LBR chr1 GO:0030099 Not Cancer Driver No 95 0.154 130 15 0.115 5
LEF1 LEF1 Q9UJU2 Lymphoid enhancer-binding factor 1 chr4 GO:0030099 Census Yes 64 0.16 370 57 0.154 0
LGALS9 LGALS9 O00182 Galectin-9 chr17 GO:0030099 Not Cancer Driver No 54 0.152 65 16 0.246 0
LTBR LTBR P36941 Tumor necrosis factor receptor superfamily member 3 chr12 GO:0030099 Not Cancer Driver No 44 0.101 200 21 0.105 0
MB_ENST00000397328 MB P02144 Myoglobin chr22 GO:0030099 Not Cancer Driver No 13 0.084 38 4 0.105 0
MED1 MED1 Q15648 Mediator of RNA polymerase II transcription subunit 1 chr17 GO:0030099 Not Cancer Driver No 162 0.102 1104 117 0.106 0
MEF2C_ENST00000504921 MEF2C Q06413 Myocyte-specific enhancer factor 2C chr5 GO:0030099 Not Cancer Driver No 92 0.195 408 81 0.199 0
MMP9 MMP9 P14780 Matrix metalloproteinase-9 chr20 GO:0030099 Not Cancer Driver No 129 0.182 124 26 0.21 0
MPIG6B MPIG6B O95866 Megakaryocyte and platelet inhibitory receptor G6b chr6 GO:0030099 Not Cancer Driver No 37 0.154 61 7 0.115 0
MT1G MT1G P13640 Metallothionein-1G chr16 GO:0030099 Not Cancer Driver No 9 0.145 0 0 0.0 0
MYH9 MYH9 P35579 Myosin-9 chr22 GO:0030099 Census, Compendium Yes 310 0.158 1120 160 0.143 17
NBEAL2 NBEAL2 Q6ZNJ1 Neurobeachin-like protein 2 chr3 GO:0030099 Not Cancer Driver No 295 0.107 515 59 0.115 8
NCOA6 NCOA6 Q14686 Nuclear receptor coactivator 6 chr20 GO:0030099 Not Cancer Driver No 242 0.117 1941 219 0.113 0
NKAP NKAP Q8N5F7 NF-kappa-B-activating protein chrX GO:0030099 Not Cancer Driver No 80 0.193 409 77 0.188 3
NKX2-3 NKX2-3 Q8TAU0 Homeobox protein Nkx-2.3 chr10 GO:0030099 Not Cancer Driver No 31 0.085 212 27 0.127 0
NOTCH2 NOTCH2 Q04721 Neurogenic locus notch homolog protein 2 chr1 GO:0030099 Census, Compendium Yes 282 0.114 630 77 0.122 1
OCSTAMP OCSTAMP Q9BR26 Osteoclast stimulatory transmembrane protein chr20 GO:0030099 Not Cancer Driver No 22 0.039 52 6 0.115 0
PARP1 PARP1 P09874 Poly [ADP-ribose] polymerase 1 chr1 GO:0030099 Not Cancer Driver No 119 0.117 320 34 0.106 0
PDE1B PDE1B Q01064 Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B chr12 GO:0030099 Not Cancer Driver No 114 0.213 132 30 0.227 0
PIK3CD PIK3CD O00329 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform chr1 GO:0030099 Not Cancer Driver No 140 0.134 60 13 0.217 1
PIR_ENST00000380420 PIR O00625 Pirin chrX GO:0030099 Not Cancer Driver No 29 0.1 185 16 0.086 0
PML PML P29590 Protein PML chr15 GO:0030099 Census, Compendium Yes 112 0.127 312 34 0.109 0
PPARG PPARG P37231 Peroxisome proliferator-activated receptor gamma chr3 GO:0030099 Census Yes 72 0.143 44 4 0.091 3
PRDX3 PRDX3 P30048 Thioredoxin-dependent peroxide reductase, mitochondrial chr10 GO:0030099 Not Cancer Driver No 23 0.09 23 3 0.13 0
PRKX PRKX P51817 cAMP-dependent protein kinase catalytic subunit PRKX chrX GO:0030099 Not Cancer Driver No 54 0.151 69 3 0.043 0
PRTN3 PRTN3 P24158 Myeloblastin chr19 GO:0030099 Not Cancer Driver No 20 0.078 46 1 0.022 0
PSEN1 PSEN1 P49768 Presenilin-1 chr14 GO:0030099 Not Cancer Driver No 61 0.131 134 21 0.157 96
PTPN11_ENST00000351677 PTPN11 Q06124 Tyrosine-protein phosphatase non-receptor type 11 chr12 GO:0030099 Census, Compendium Yes 129 0.218 260 38 0.146 60
PTPN6_ENST00000318974 PTPN6 P29350 Tyrosine-protein phosphatase non-receptor type 6 chr12 GO:0030099 Census, Compendium Yes 73 0.123 192 25 0.13 0
RASGRP4_ENST00000587738 RASGRP4 Q8TDF6 RAS guanyl-releasing protein 4 chr19 GO:0030099 Not Cancer Driver No 96 0.143 184 40 0.217 0
RB1 RB1 P06400 Retinoblastoma-associated protein chr13 GO:0030099 Census, Compendium Yes 140 0.151 282 32 0.113 22
RBPJ_ENST00000361572 RBPJ Q06330 Recombining binding protein suppressor of hairless chr4 GO:0030099 Not Cancer Driver No 49 0.098 151 19 0.126 2
RELB RELB Q01201 Transcription factor RelB chr19 GO:0030099 Not Cancer Driver No 65 0.112 348 39 0.112 0
RUNX1_ENST00000344691 RUNX1 Q01196 Runt-related transcription factor 1 chr21 GO:0030099 Census, Compendium Yes 81 0.179 360 58 0.161 2
SIRT1 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 GO:0030099 Not Cancer Driver No 70 0.094 435 31 0.071 0
SNRK SNRK Q9NRH2 SNF-related serine/threonine-protein kinase chr3 GO:0030099 Not Cancer Driver No 82 0.107 368 47 0.128 0
SP3 SP3 Q02447 Transcription factor Sp3 chr2 GO:0030099 Not Cancer Driver No 66 0.085 587 37 0.063 0
SPI1_ENST00000378538 SPI1 P17947 Transcription factor PU.1 chr11 GO:0030099 Not Cancer Driver No 46 0.17 187 34 0.182 0
SRF SRF P11831 Serum response factor chr6 GO:0030099 Not Cancer Driver No 44 0.087 443 42 0.095 0
SRP54 SRP54 P61011 Signal recognition particle 54 kDa protein chr14 GO:0030099 Not Cancer Driver No 53 0.105 115 13 0.113 7
TAL1 TAL1 P17542 T-cell acute lymphocytic leukemia protein 1 chr1 GO:0030099 Census Yes 54 0.163 305 53 0.174 0
TET2 TET2 Q6N021 Methylcytosine dioxygenase TET2 chr4 GO:0030099 Census, Compendium Yes 191 0.095 1663 176 0.106 1
TGFBR2_ENST00000295754 TGFBR2 P37173 TGF-beta receptor type-2 chr3 GO:0030099 Census, Compendium Yes 106 0.187 60 16 0.267 25
TGFBR3_ENST00000525962 TGFBR3 Q03167 Transforming growth factor beta receptor type 3 chr1 GO:0030099 Not Cancer Driver No 129 0.152 268 41 0.153 0
THOC5_ENST00000397872 THOC5 Q13769 THO complex subunit 5 homolog chr22 GO:0030099 Not Cancer Driver No 88 0.129 173 25 0.145 0
TIRAP_ENST00000392680 TIRAP P58753 Toll/interleukin-1 receptor domain-containing adapter protein chr11 GO:0030099 Not Cancer Driver No 28 0.127 80 6 0.075 0
TNFRSF11A TNFRSF11A Q9Y6Q6 Tumor necrosis factor receptor superfamily member 11A chr18 GO:0030099 Not Cancer Driver No 70 0.114 285 33 0.116 0
TRAF6_ENST00000348124 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 GO:0030099 Not Cancer Driver No 67 0.128 62 7 0.113 0
TSPO2 TSPO2 Q5TGU0 Translocator protein 2 chr6 GO:0030099 Not Cancer Driver No 23 0.135 7 3 0.429 0
UBA5 UBA5 Q9GZZ9 Ubiquitin-like modifier-activating enzyme 5 chr3 GO:0030099 Not Cancer Driver No 41 0.101 126 8 0.063 7
UBD UBD O15205 Ubiquitin D chr6 GO:0030099 Not Cancer Driver No 31 0.188 8 1 0.125 0
VEGFA_ENST00000523873 VEGFA P15692 Vascular endothelial growth factor A chr6 GO:0030099 Not Cancer Driver No 27 0.116 41 7 0.171 0
VPS33A VPS33A Q96AX1 Vacuolar protein sorting-associated protein 33A chr12 GO:0030099 Not Cancer Driver No 73 0.122 46 8 0.174 1
WDR1 WDR1 O75083 WD repeat-containing protein 1 chr4 GO:0030099 Not Cancer Driver No 66 0.109 30 7 0.233 2
ZBTB16_ENST00000392996 ZBTB16 Q05516 Zinc finger and BTB domain-containing protein 16 chr11 GO:0030099 Census, Compendium Yes 131 0.195 268 50 0.187 1
ZFPM1 ZFPM1 Q8IX07 Zinc finger protein ZFPM1 chr16 GO:0030099 Not Cancer Driver No 50 0.05 772 27 0.035 0
ZNF385A ZNF385A Q96PM9 Zinc finger protein 385A chr12 GO:0030099 Not Cancer Driver No 43 0.111 312 34 0.109 0