Total number of protein in "GO:0030010" GO term: 86
Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ALPK2 | ALPK2 | Q86TB3 | Alpha-protein kinase 2 | chr18 | GO:0030010 | Not Cancer Driver | No | 406 | 0.187 | 1553 | 306 | 0.197 | 0 |
AMOT | AMOT | Q4VCS5 | Angiomotin | chrX | GO:0030010 | Not Cancer Driver | No | 161 | 0.149 | 909 | 128 | 0.141 | 0 |
AMOTL1 | AMOTL1 | Q8IY63 | Angiomotin-like protein 1 | chr11 | GO:0030010 | Not Cancer Driver | No | 136 | 0.142 | 851 | 121 | 0.142 | 0 |
AMOTL2_ENST00000422605 | AMOTL2 | Q9Y2J4 | Angiomotin-like protein 2 | chr3 | GO:0030010 | Not Cancer Driver | No | 94 | 0.121 | 741 | 93 | 0.126 | 0 |
ARF6 | ARF6 | P62330 | ADP-ribosylation factor 6 | chr14 | GO:0030010 | Not Cancer Driver | No | 18 | 0.103 | 5 | 0 | 0.0 | 0 |
ARHGEF11_ENST00000361409 | ARHGEF11 | O15085 | Rho guanine nucleotide exchange factor 11 | chr1 | GO:0030010 | Not Cancer Driver | No | 213 | 0.14 | 1036 | 138 | 0.133 | 0 |
BRSK1 | BRSK1 | Q8TDC3 | Serine/threonine-protein kinase BRSK1 | chr19 | GO:0030010 | Not Cancer Driver | No | 131 | 0.168 | 459 | 78 | 0.17 | 0 |
BRSK2_ENST00000528841 | BRSK2 | Q8IWQ3 | Serine/threonine-protein kinase BRSK2 | chr11 | GO:0030010 | Not Cancer Driver | No | 90 | 0.122 | 321 | 39 | 0.121 | 0 |
CAMSAP3_ENST00000160298 | CAMSAP3 | Q9P1Y5 | Calmodulin-regulated spectrin-associated protein 3 | chr19 | GO:0030010 | Not Cancer Driver | No | 132 | 0.106 | 889 | 81 | 0.091 | 0 |
CCL19 | CCL19 | Q99731 | C-C motif chemokine 19 | chr9 | GO:0030010 | Not Cancer Driver | No | 10 | 0.102 | 7 | 0 | 0.0 | 0 |
CCL21 | CCL21 | O00585 | C-C motif chemokine 21 | chr9 | GO:0030010 | Not Cancer Driver | No | 14 | 0.104 | 59 | 6 | 0.102 | 0 |
CCR7 | CCR7 | P32248 | C-C chemokine receptor type 7 | chr17 | GO:0030010 | Census, Compendium | Yes | 50 | 0.132 | 0 | 0 | 0.0 | 0 |
CDC42_ENST00000344548 | CDC42 | P60953 | Cell division control protein 42 homolog | chr1 | GO:0030010 | Not Cancer Driver | No | 39 | 0.204 | 23 | 2 | 0.087 | 1 |
CLASP1_ENST00000646274 | CLASP1 | Q7Z460 | CLIP-associating protein 1 | chr2 | GO:0030010 | Not Cancer Driver | No | 163 | 0.106 | 642 | 70 | 0.109 | 0 |
CRB1 | CRB1 | P82279 | Protein crumbs homolog 1 | chr1 | GO:0030010 | Not Cancer Driver | No | 464 | 0.33 | 28 | 5 | 0.179 | 74 |
CRB2 | CRB2 | Q5IJ48 | Protein crumbs homolog 2 | chr9 | GO:0030010 | Not Cancer Driver | No | 155 | 0.121 | 72 | 0 | 0.0 | 5 |
CRK | CRK | P46108 | Adapter molecule crk | chr17 | GO:0030010 | Not Cancer Driver | No | 30 | 0.099 | 197 | 23 | 0.117 | 0 |
CRKL | CRKL | P46109 | Crk-like protein | chr22 | GO:0030010 | Not Cancer Driver | No | 38 | 0.125 | 160 | 25 | 0.156 | 0 |
CRTAM | CRTAM | O95727 | Cytotoxic and regulatory T-cell molecule | chr11 | GO:0030010 | Not Cancer Driver | No | 64 | 0.163 | 135 | 14 | 0.104 | 0 |
CYP26B1 | CYP26B1 | Q9NR63 | Cytochrome P450 26B1 | chr2 | GO:0030010 | Not Cancer Driver | No | 113 | 0.221 | 10 | 3 | 0.3 | 2 |
CYTH1_ENST00000446868 | CYTH1 | Q15438 | Cytohesin-1 | chr17 | GO:0030010 | Not Cancer Driver | No | 59 | 0.148 | 93 | 15 | 0.161 | 0 |
CYTH3_ENST00000396741 | CYTH3 | O43739 | Cytohesin-3 | chr7 | GO:0030010 | Not Cancer Driver | No | 49 | 0.122 | 96 | 12 | 0.125 | 0 |
DOCK2 | DOCK2 | Q92608 | Dedicator of cytokinesis protein 2 | chr5 | GO:0030010 | Not Cancer Driver | No | 480 | 0.262 | 266 | 79 | 0.297 | 2 |
DOCK7_ENST00000635253 | DOCK7 | Q96N67 | Dedicator of cytokinesis protein 7 | chr1 | GO:0030010 | Not Cancer Driver | No | 262 | 0.122 | 454 | 53 | 0.117 | 0 |
EPHB1 | EPHB1 | P54762 | Ephrin type-B receptor 1 | chr3 | GO:0030010 | Not Cancer Driver | No | 316 | 0.321 | 67 | 17 | 0.254 | 0 |
EZR | EZR | P15311 | Ezrin | chr6 | GO:0030010 | Census | Yes | 66 | 0.113 | 295 | 35 | 0.119 | 0 |
FAM89B | FAM89B | Q8N5H3 | Leucine repeat adapter protein 25 | chr11 | GO:0030010 | Not Cancer Driver | No | 14 | 0.074 | 108 | 11 | 0.102 | 0 |
FAT1 | FAT1 | Q14517 | Protocadherin Fat 1 | chr4 | GO:0030010 | Census, Compendium | Yes | 663 | 0.145 | 1051 | 126 | 0.12 | 0 |
FBF1_ENST00000586717 | FBF1 | Q8TES7 | Fas-binding factor 1 | chr17 | GO:0030010 | Not Cancer Driver | No | 125 | 0.11 | 1066 | 116 | 0.109 | 0 |
FERMT1 | FERMT1 | Q9BQL6 | Fermitin family homolog 1 | chr20 | GO:0030010 | Not Cancer Driver | No | 100 | 0.148 | 65 | 8 | 0.123 | 2 |
FEZ1 | FEZ1 | Q99689 | Fasciculation and elongation protein zeta-1 | chr11 | GO:0030010 | Not Cancer Driver | No | 66 | 0.168 | 277 | 49 | 0.177 | 0 |
FGF13_ENST00000315930 | FGF13 | Q92913 | Fibroblast growth factor 13 | chrX | GO:0030010 | Not Cancer Driver | No | 70 | 0.286 | 96 | 33 | 0.344 | 2 |
FOXF1 | FOXF1 | Q12946 | Forkhead box protein F1 | chr16 | GO:0030010 | Not Cancer Driver | No | 56 | 0.148 | 194 | 20 | 0.103 | 20 |
FOXJ1 | FOXJ1 | Q92949 | Forkhead box protein J1 | chr17 | GO:0030010 | Not Cancer Driver | No | 25 | 0.059 | 279 | 18 | 0.065 | 0 |
FRMD4A | FRMD4A | Q9P2Q2 | FERM domain-containing protein 4A | chr10 | GO:0030010 | Not Cancer Driver | No | 122 | 0.117 | 666 | 72 | 0.108 | 0 |
FRMD4B | FRMD4B | Q9Y2L6 | FERM domain-containing protein 4B | chr3 | GO:0030010 | Not Cancer Driver | No | 102 | 0.099 | 542 | 60 | 0.111 | 0 |
FSCN1 | FSCN1 | Q16658 | Fascin | chr7 | GO:0030010 | Not Cancer Driver | No | 58 | 0.118 | 81 | 5 | 0.062 | 0 |
GBF1 | GBF1 | Q92538 | Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 | chr10 | GO:0030010 | Not Cancer Driver | No | 216 | 0.116 | 669 | 76 | 0.114 | 0 |
GSK3B_ENST00000264235 | GSK3B | P49841 | Glycogen synthase kinase-3 beta | chr3 | GO:0030010 | Not Cancer Driver | No | 56 | 0.133 | 146 | 13 | 0.089 | 0 |
HES1 | HES1 | Q14469 | Transcription factor HES-1 | chr3 | GO:0030010 | Not Cancer Driver | No | 37 | 0.132 | 226 | 32 | 0.142 | 0 |
HES5 | HES5 | Q5TA89 | Transcription factor HES-5 | chr1 | GO:0030010 | Not Cancer Driver | No | 1 | 0.006 | 73 | 0 | 0.0 | 0 |
HSP90AA1_ENST00000216281 | HSP90AA1 | P07900 | Heat shock protein HSP 90-alpha | chr14 | GO:0030010 | Census, Compendium | Yes | 106 | 0.145 | 257 | 37 | 0.144 | 0 |
HSP90AB1 | HSP90AB1 | P08238 | Heat shock protein HSP 90-beta | chr6 | GO:0030010 | Census, Compendium | Yes | 100 | 0.138 | 254 | 43 | 0.169 | 0 |
IFT20_ENST00000395418 | IFT20 | Q8IY31 | Intraflagellar transport protein 20 homolog | chr17 | GO:0030010 | Not Cancer Driver | No | 11 | 0.083 | 0 | 0 | 0.0 | 0 |
IGF1R | IGF1R | P08069 | Insulin-like growth factor 1 receptor | chr15 | GO:0030010 | Not Cancer Driver | No | 183 | 0.134 | 265 | 37 | 0.14 | 6 |
JAM3 | JAM3 | Q9BX67 | Junctional adhesion molecule C | chr11 | GO:0030010 | Not Cancer Driver | No | 50 | 0.161 | 62 | 11 | 0.177 | 2 |
KIF26B | KIF26B | Q2KJY2 | Kinesin-like protein KIF26B | chr1 | GO:0030010 | Not Cancer Driver | No | 369 | 0.175 | 1412 | 198 | 0.14 | 0 |
LAMA1 | LAMA1 | P25391 | Laminin subunit alpha-1 | chr18 | GO:0030010 | Not Cancer Driver | No | 600 | 0.195 | 329 | 71 | 0.216 | 0 |
MAP1B | MAP1B | P46821 | Microtubule-associated protein 1B | chr5 | GO:0030010 | Not Cancer Driver | No | 332 | 0.135 | 1947 | 278 | 0.143 | 0 |
MARK2 | MARK2 | Q7KZI7 | Serine/threonine-protein kinase MARK2 | chr11 | GO:0030010 | Compendium | Yes | 124 | 0.157 | 445 | 70 | 0.157 | 0 |
MPP7 | MPP7 | Q5T2T1 | MAGUK p55 subfamily member 7 | chr10 | GO:0030010 | Not Cancer Driver | No | 132 | 0.229 | 199 | 72 | 0.362 | 0 |
MSN | MSN | P26038 | Moesin | chrX | GO:0030010 | Census, Compendium | Yes | 108 | 0.187 | 286 | 56 | 0.196 | 1 |
MYH9 | MYH9 | P35579 | Myosin-9 | chr22 | GO:0030010 | Census, Compendium | Yes | 310 | 0.158 | 1120 | 160 | 0.143 | 17 |
MYO9A | MYO9A | B2RTY4 | Unconventional myosin-IXa | chr15 | GO:0030010 | Not Cancer Driver | No | 323 | 0.127 | 970 | 131 | 0.135 | 0 |
NEK3 | NEK3 | P51956 | Serine/threonine-protein kinase Nek3 | chr13 | GO:0030010 | Not Cancer Driver | No | 44 | 0.087 | 203 | 17 | 0.084 | 0 |
OPHN1 | OPHN1 | O60890 | Oligophrenin-1 | chrX | GO:0030010 | Not Cancer Driver | No | 122 | 0.152 | 302 | 42 | 0.139 | 0 |
PARD3 | PARD3 | Q8TEW0 | Partitioning defective 3 homolog | chr10 | GO:0030010 | Not Cancer Driver | No | 200 | 0.147 | 1144 | 170 | 0.149 | 2 |
PARD3B | PARD3B | Q8TEW8 | Partitioning defective 3 homolog B | chr2 | GO:0030010 | Not Cancer Driver | No | 241 | 0.2 | 977 | 203 | 0.208 | 0 |
PATJ | PATJ | Q8NI35 | InaD-like protein | chr1 | GO:0030010 | Not Cancer Driver | No | 261 | 0.145 | 918 | 142 | 0.155 | 0 |
PKD1 | PKD1 | P98161 | Polycystin-1 | chr16 | GO:0030010 | Not Cancer Driver | No | 393 | 0.091 | 690 | 66 | 0.096 | 92 |
PRKCI | PRKCI | P41743 | Protein kinase C iota type | chr3 | GO:0030010 | Not Cancer Driver | No | 110 | 0.185 | 120 | 16 | 0.133 | 0 |
PRKCZ | PRKCZ | Q05513 | Protein kinase C zeta type | chr1 | GO:0030010 | Not Cancer Driver | No | 70 | 0.118 | 116 | 11 | 0.095 | 0 |
PTK2_ENST00000522684 | PTK2 | Q05397 | Focal adhesion kinase 1 | chr8 | GO:0030010 | Not Cancer Driver | No | 134 | 0.127 | 425 | 55 | 0.129 | 0 |
PTK7_ENST00000230419 | PTK7 | Q13308 | Inactive tyrosine-protein kinase 7 | chr6 | GO:0030010 | Not Cancer Driver | No | 153 | 0.143 | 359 | 58 | 0.162 | 0 |
RAB10 | RAB10 | P61026 | Ras-related protein Rab-10 | chr2 | GO:0030010 | Not Cancer Driver | No | 19 | 0.095 | 28 | 2 | 0.071 | 0 |
RAB11FIP2_ENST00000355624 | RAB11FIP2 | Q7L804 | Rab11 family-interacting protein 2 | chr10 | GO:0030010 | Not Cancer Driver | No | 66 | 0.129 | 356 | 43 | 0.121 | 0 |
RAP2A | RAP2A | P10114 | Ras-related protein Rap-2a | chr13 | GO:0030010 | Not Cancer Driver | No | 15 | 0.082 | 9 | 0 | 0.0 | 0 |
RHOA | RHOA | P61586 | Transforming protein RhoA | chr3 | GO:0030010 | Census, Compendium | Yes | 99 | 0.513 | 46 | 13 | 0.283 | 2 |
SCRIB_ENST00000320476 | SCRIB | Q14160 | Protein scribble homolog | chr8 | GO:0030010 | Not Cancer Driver | No | 196 | 0.12 | 1064 | 135 | 0.127 | 2 |
SDCCAG8 | SDCCAG8 | Q86SQ7 | Serologically defined colon cancer antigen 8 | chr1 | GO:0030010 | Not Cancer Driver | No | 110 | 0.154 | 487 | 73 | 0.15 | 0 |
SH3BP1 | SH3BP1 | Q9Y3L3 | SH3 domain-binding protein 1 | chr22 | GO:0030010 | Not Cancer Driver | No | 57 | 0.081 | 430 | 31 | 0.072 | 0 |
SHH | SHH | Q15465 | Sonic hedgehog protein | chr7 | GO:0030010 | Not Cancer Driver | No | 56 | 0.121 | 139 | 14 | 0.101 | 81 |
SIPA1L3 | SIPA1L3 | O60292 | Signal-induced proliferation-associated 1-like protein 3 | chr19 | GO:0030010 | Not Cancer Driver | No | 273 | 0.153 | 1257 | 190 | 0.151 | 0 |
SLC9A3R1 | SLC9A3R1 | O14745 | Na(+)/H(+) exchange regulatory cofactor NHE-RF1 | chr17 | GO:0030010 | Not Cancer Driver | No | 19 | 0.053 | 318 | 16 | 0.05 | 4 |
SNX27 | SNX27 | Q96L92 | Sorting nexin-27 | chr1 | GO:0030010 | Not Cancer Driver | No | 65 | 0.12 | 120 | 9 | 0.075 | 0 |
STK11 | STK11 | Q15831 | Serine/threonine-protein kinase STK11 | chr19 | GO:0030010 | Census, Compendium | Yes | 75 | 0.173 | 135 | 14 | 0.104 | 9 |
SYNE4 | SYNE4 | Q8N205 | Nesprin-4 | chr19 | GO:0030010 | Not Cancer Driver | No | 50 | 0.124 | 236 | 31 | 0.131 | 0 |
TCF15 | TCF15 | Q12870 | Transcription factor 15 | chr20 | GO:0030010 | Not Cancer Driver | No | 19 | 0.095 | 134 | 4 | 0.03 | 0 |
TCIRG1 | TCIRG1 | Q13488 | V-type proton ATPase 116 kDa subunit a 3 | chr11 | GO:0030010 | Compendium | Yes | 68 | 0.082 | 102 | 6 | 0.059 | 5 |
TRAF3IP2_ENST00000392556 | TRAF3IP2 | O43734 | E3 ubiquitin ligase TRAF3IP2 | chr6 | GO:0030010 | Not Cancer Driver | No | 59 | 0.103 | 410 | 39 | 0.095 | 2 |
TTC8_ENST00000338104 | TTC8 | Q8TAM2 | Tetratricopeptide repeat protein 8 | chr14 | GO:0030010 | Not Cancer Driver | No | 74 | 0.137 | 98 | 12 | 0.122 | 0 |
UST | UST | Q9Y2C2 | Uronyl 2-sulfotransferase | chr6 | GO:0030010 | Not Cancer Driver | No | 70 | 0.172 | 57 | 8 | 0.14 | 0 |
WEE1 | WEE1 | P30291 | Wee1-like protein kinase | chr11 | GO:0030010 | Not Cancer Driver | No | 60 | 0.093 | 399 | 27 | 0.068 | 0 |
WNT5A_ENST00000474267 | WNT5A | P41221 | Protein Wnt-5a | chr3 | GO:0030010 | Not Cancer Driver | No | 66 | 0.174 | 0 | 0 | 0.0 | 2 |
WNT7A | WNT7A | O00755 | Protein Wnt-7a | chr3 | GO:0030010 | Not Cancer Driver | No | 93 | 0.266 | 18 | 9 | 0.5 | 4 |
WWC1_ENST00000265293 | WWC1 | Q8IX03 | Protein KIBRA | chr5 | GO:0030010 | Not Cancer Driver | No | 147 | 0.132 | 550 | 81 | 0.147 | 0 |