Total number of protein in "GO:0022832" GO term: 95
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABCC8_ENST00000389817 | ABCC8 | Q09428 | ATP-binding cassette sub-family C member 8 | chr11 | GO:0022832 | Not Cancer Driver | No | 255 | 0.161 | 138 | 23 | 0.167 | 97 |
| ABCC9_ENST00000261201 | ABCC9 | O60706 | ATP-binding cassette sub-family C member 9 | chr12 | GO:0022832 | Not Cancer Driver | No | 368 | 0.238 | 132 | 30 | 0.227 | 15 |
| ANO1 | ANO1 | Q5XXA6 | Anoctamin-1 | chr11 | GO:0022832 | Not Cancer Driver | No | 155 | 0.157 | 168 | 14 | 0.083 | 0 |
| ANO6_ENST00000320560 | ANO6 | Q4KMQ2 | Anoctamin-6 | chr12 | GO:0022832 | Not Cancer Driver | No | 134 | 0.147 | 80 | 11 | 0.138 | 0 |
| CACNA1A_ENST00000360228 | CACNA1A | O00555 | Voltage-dependent P/Q-type calcium channel subunit alpha-1A | chr19 | GO:0022832 | Not Cancer Driver | No | 436 | 0.174 | 1144 | 132 | 0.115 | 46 |
| CACNA1B | CACNA1B | Q00975 | Voltage-dependent N-type calcium channel subunit alpha-1B | chr9 | GO:0022832 | Not Cancer Driver | No | 416 | 0.178 | 917 | 115 | 0.125 | 0 |
| CACNA1C | CACNA1C | Q13936 | Voltage-dependent L-type calcium channel subunit alpha-1C | chr12 | GO:0022832 | Not Cancer Driver | No | 455 | 0.205 | 744 | 146 | 0.196 | 14 |
| CACNA1D_ENST00000350061 | CACNA1D | Q01668 | Voltage-dependent L-type calcium channel subunit alpha-1D | chr3 | GO:0022832 | Census, Compendium | Yes | 342 | 0.158 | 736 | 126 | 0.171 | 2 |
| CACNA1E_ENST00000621551 | CACNA1E | Q15878 | Voltage-dependent R-type calcium channel subunit alpha-1E | chr1 | GO:0022832 | Not Cancer Driver | No | 778 | 0.336 | 917 | 339 | 0.37 | 14 |
| CACNA1F | CACNA1F | O60840 | Voltage-dependent L-type calcium channel subunit alpha-1F | chrX | GO:0022832 | Not Cancer Driver | No | 284 | 0.144 | 530 | 78 | 0.147 | 20 |
| CACNA1G | CACNA1G | O43497 | Voltage-dependent T-type calcium channel subunit alpha-1G | chr17 | GO:0022832 | Not Cancer Driver | No | 367 | 0.154 | 1022 | 149 | 0.146 | 3 |
| CACNA1H | CACNA1H | O95180 | Voltage-dependent T-type calcium channel subunit alpha-1H | chr16 | GO:0022832 | Not Cancer Driver | No | 323 | 0.137 | 1045 | 141 | 0.135 | 18 |
| CACNA1I | CACNA1I | Q9P0X4 | Voltage-dependent T-type calcium channel subunit alpha-1I | chr22 | GO:0022832 | Not Cancer Driver | No | 272 | 0.122 | 870 | 73 | 0.084 | 0 |
| CACNA1S | CACNA1S | Q13698 | Voltage-dependent L-type calcium channel subunit alpha-1S | chr1 | GO:0022832 | Not Cancer Driver | No | 389 | 0.208 | 382 | 76 | 0.199 | 6 |
| CACNA2D1_ENST00000356253 | CACNA2D1 | P54289 | Voltage-dependent calcium channel subunit alpha-2/delta-1 | chr7 | GO:0022832 | Not Cancer Driver | No | 277 | 0.251 | 99 | 25 | 0.253 | 0 |
| CACNB1 | CACNB1 | Q02641 | Voltage-dependent L-type calcium channel subunit beta-1 | chr17 | GO:0022832 | Not Cancer Driver | No | 75 | 0.125 | 396 | 47 | 0.119 | 0 |
| CACNB2 | CACNB2 | Q08289 | Voltage-dependent L-type calcium channel subunit beta-2 | chr10 | GO:0022832 | Not Cancer Driver | No | 155 | 0.235 | 478 | 106 | 0.222 | 0 |
| CACNB3 | CACNB3 | P54284 | Voltage-dependent L-type calcium channel subunit beta-3 | chr12 | GO:0022832 | Not Cancer Driver | No | 58 | 0.12 | 258 | 30 | 0.116 | 0 |
| CACNB4 | CACNB4 | O00305 | Voltage-dependent L-type calcium channel subunit beta-4 | chr2 | GO:0022832 | Not Cancer Driver | No | 82 | 0.158 | 295 | 49 | 0.166 | 1 |
| CDK5 | CDK5 | Q00535 | Cyclin-dependent kinase 5 | chr7 | GO:0022832 | Not Cancer Driver | No | 48 | 0.164 | 5 | 1 | 0.2 | 0 |
| CLCN1 | CLCN1 | P35523 | Chloride channel protein 1 | chr7 | GO:0022832 | Not Cancer Driver | No | 224 | 0.227 | 355 | 77 | 0.217 | 54 |
| CLCN2 | CLCN2 | P51788 | Chloride channel protein 2 | chr3 | GO:0022832 | Not Cancer Driver | No | 124 | 0.138 | 224 | 38 | 0.17 | 8 |
| CLCN3_ENST00000513761 | CLCN3 | P51790 | H(+)/Cl(-) exchange transporter 3 | chr4 | GO:0022832 | Not Cancer Driver | No | 105 | 0.128 | 88 | 7 | 0.08 | 0 |
| CLCN4 | CLCN4 | P51793 | H(+)/Cl(-) exchange transporter 4 | chrX | GO:0022832 | Not Cancer Driver | No | 118 | 0.155 | 62 | 13 | 0.21 | 11 |
| CLCN5 | CLCN5 | P51795 | H(+)/Cl(-) exchange transporter 5 | chrX | GO:0022832 | Not Cancer Driver | No | 138 | 0.169 | 81 | 6 | 0.074 | 32 |
| CLCN6 | CLCN6 | P51797 | H(+)/Cl(-) exchange transporter 6 | chr1 | GO:0022832 | Not Cancer Driver | No | 123 | 0.142 | 109 | 24 | 0.22 | 1 |
| CLCN7 | CLCN7 | P51798 | H(+)/Cl(-) exchange transporter 7 | chr16 | GO:0022832 | Not Cancer Driver | No | 102 | 0.127 | 94 | 7 | 0.074 | 29 |
| CLCNKA | CLCNKA | P51800 | Chloride channel protein ClC-Ka | chr1 | GO:0022832 | Not Cancer Driver | No | 92 | 0.134 | 35 | 3 | 0.086 | 1 |
| CLCNKB | CLCNKB | P51801 | Chloride channel protein ClC-Kb | chr1 | GO:0022832 | Not Cancer Driver | No | 104 | 0.151 | 23 | 9 | 0.391 | 5 |
| CNR1_ENST00000549890 | CNR1 | P21554 | Cannabinoid receptor 1 | chr6 | GO:0022832 | Not Cancer Driver | No | 129 | 0.273 | 9 | 1 | 0.111 | 0 |
| GPR89A | GPR89A | B7ZAQ6 | Golgi pH regulator A | chr1 | GO:0022832 | Not Cancer Driver | No | 22 | 0.048 | 1 | 0 | 0.0 | 0 |
| GPR89B | GPR89B | P0CG08 | Golgi pH regulator B | chr1 | GO:0022832 | Not Cancer Driver | No | 11 | 0.024 | 1 | 0 | 0.0 | 0 |
| GRIN1_ENST00000371561 | GRIN1 | Q05586 | Glutamate receptor ionotropic, NMDA 1 | chr9 | GO:0022832 | Not Cancer Driver | No | 88 | 0.094 | 190 | 15 | 0.079 | 13 |
| GRIN2A_ENST00000330684 | GRIN2A | Q12879 | Glutamate receptor ionotropic, NMDA 2A | chr16 | GO:0022832 | Census, Compendium | Yes | 528 | 0.361 | 506 | 207 | 0.409 | 31 |
| GRIN2B | GRIN2B | Q13224 | Glutamate receptor ionotropic, NMDA 2B | chr12 | GO:0022832 | Not Cancer Driver | No | 413 | 0.278 | 426 | 147 | 0.345 | 11 |
| GRIN2C | GRIN2C | Q14957 | Glutamate receptor ionotropic, NMDA 2C | chr17 | GO:0022832 | Not Cancer Driver | No | 111 | 0.09 | 276 | 6 | 0.022 | 0 |
| GRIN2D | GRIN2D | O15399 | Glutamate receptor ionotropic, NMDA 2D | chr19 | GO:0022832 | Not Cancer Driver | No | 125 | 0.094 | 467 | 15 | 0.032 | 1 |
| GRIN3A | GRIN3A | Q8TCU5 | Glutamate receptor ionotropic, NMDA 3A | chr9 | GO:0022832 | Not Cancer Driver | No | 308 | 0.276 | 179 | 22 | 0.123 | 0 |
| GRIN3B | GRIN3B | O60391 | Glutamate receptor ionotropic, NMDA 3B | chr19 | GO:0022832 | Not Cancer Driver | No | 90 | 0.086 | 299 | 23 | 0.077 | 0 |
| HCN4 | HCN4 | Q9Y3Q4 | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | chr15 | GO:0022832 | Not Cancer Driver | No | 187 | 0.155 | 631 | 58 | 0.092 | 3 |
| HTR1B | HTR1B | P28222 | 5-hydroxytryptamine receptor 1B | chr6 | GO:0022832 | Not Cancer Driver | No | 91 | 0.233 | 33 | 15 | 0.455 | 0 |
| HVCN1_ENST00000620084 | HVCN1 | Q96D96 | Voltage-gated hydrogen channel 1 | chr12 | GO:0022832 | Not Cancer Driver | No | 51 | 0.187 | 52 | 13 | 0.25 | 0 |
| KCNA1 | KCNA1 | Q09470 | Potassium voltage-gated channel subfamily A member 1 | chr12 | GO:0022832 | Not Cancer Driver | No | 176 | 0.356 | 69 | 34 | 0.493 | 17 |
| KCNA2_ENST00000638616 | KCNA2 | P16389 | Potassium voltage-gated channel subfamily A member 2 | chr1 | GO:0022832 | Not Cancer Driver | No | 96 | 0.192 | 82 | 16 | 0.195 | 5 |
| KCNA3 | KCNA3 | P22001 | Potassium voltage-gated channel subfamily A member 3 | chr1 | GO:0022832 | Not Cancer Driver | No | 120 | 0.209 | 169 | 16 | 0.095 | 0 |
| KCNA5 | KCNA5 | P22460 | Potassium voltage-gated channel subfamily A member 5 | chr12 | GO:0022832 | Not Cancer Driver | No | 213 | 0.347 | 218 | 53 | 0.243 | 0 |
| KCNB1_ENST00000635465 | KCNB1 | Q14721 | Potassium voltage-gated channel subfamily B member 1 | chr20 | GO:0022832 | Not Cancer Driver | No | 192 | 0.224 | 417 | 100 | 0.24 | 6 |
| KCNC1_ENST00000379472 | KCNC1 | P48547 | Potassium voltage-gated channel subfamily C member 1 | chr11 | GO:0022832 | Not Cancer Driver | No | 91 | 0.178 | 110 | 18 | 0.164 | 1 |
| KCNC2 | KCNC2 | Q96PR1 | Potassium voltage-gated channel subfamily C member 2 | chr12 | GO:0022832 | Not Cancer Driver | No | 161 | 0.252 | 255 | 63 | 0.247 | 0 |
| KCND1 | KCND1 | Q9NSA2 | Potassium voltage-gated channel subfamily D member 1 | chrX | GO:0022832 | Not Cancer Driver | No | 97 | 0.15 | 180 | 30 | 0.167 | 0 |
| KCND2 | KCND2 | Q9NZV8 | Potassium voltage-gated channel subfamily D member 2 | chr7 | GO:0022832 | Not Cancer Driver | No | 220 | 0.349 | 195 | 62 | 0.318 | 0 |
| KCND3 | KCND3 | Q9UK17 | Potassium voltage-gated channel subfamily D member 3 | chr1 | GO:0022832 | Not Cancer Driver | No | 172 | 0.263 | 202 | 44 | 0.218 | 5 |
| KCNE1_ENST00000399284 | KCNE1 | P15382 | Potassium voltage-gated channel subfamily E member 1 | chr21 | GO:0022832 | Not Cancer Driver | No | 35 | 0.271 | 24 | 10 | 0.417 | 9 |
| KCNE2 | KCNE2 | Q9Y6J6 | Potassium voltage-gated channel subfamily E member 2 | chr21 | GO:0022832 | Not Cancer Driver | No | 25 | 0.203 | 2 | 0 | 0.0 | 5 |
| KCNE3 | KCNE3 | Q9Y6H6 | Potassium voltage-gated channel subfamily E member 3 | chr11 | GO:0022832 | Not Cancer Driver | No | 28 | 0.272 | 24 | 2 | 0.083 | 0 |
| KCNE4 | KCNE4 | Q8WWG9 | Potassium voltage-gated channel subfamily E member 4 | chr2 | GO:0022832 | Not Cancer Driver | No | 26 | 0.118 | 94 | 18 | 0.191 | 0 |
| KCNE5 | KCNE5 | Q9UJ90 | Potassium voltage-gated channel subfamily E regulatory beta subunit 5 | chrX | GO:0022832 | Not Cancer Driver | No | 35 | 0.246 | 68 | 26 | 0.382 | 0 |
| KCNH2 | KCNH2 | Q12809 | Potassium voltage-gated channel subfamily H member 2 | chr7 | GO:0022832 | Not Cancer Driver | No | 189 | 0.163 | 466 | 50 | 0.107 | 117 |
| KCNH6 | KCNH6 | Q9H252 | Potassium voltage-gated channel subfamily H member 6 | chr17 | GO:0022832 | Not Cancer Driver | No | 202 | 0.203 | 284 | 67 | 0.236 | 0 |
| KCNH7 | KCNH7 | Q9NS40 | Potassium voltage-gated channel subfamily H member 7 | chr2 | GO:0022832 | Not Cancer Driver | No | 324 | 0.271 | 508 | 138 | 0.272 | 0 |
| KCNIP2_ENST00000356640 | KCNIP2 | Q9NS61 | Kv channel-interacting protein 2 | chr10 | GO:0022832 | Not Cancer Driver | No | 34 | 0.126 | 89 | 16 | 0.18 | 0 |
| KCNJ1 | KCNJ1 | P48048 | ATP-sensitive inward rectifier potassium channel 1 | chr11 | GO:0022832 | Not Cancer Driver | No | 83 | 0.212 | 10 | 0 | 0.0 | 13 |
| KCNJ10 | KCNJ10 | P78508 | ATP-sensitive inward rectifier potassium channel 10 | chr1 | GO:0022832 | Not Cancer Driver | No | 78 | 0.206 | 28 | 10 | 0.357 | 8 |
| KCNJ11 | KCNJ11 | Q14654 | ATP-sensitive inward rectifier potassium channel 11 | chr11 | GO:0022832 | Not Cancer Driver | No | 48 | 0.123 | 19 | 3 | 0.158 | 46 |
| KCNJ12_ENST00000331718 | KCNJ12 | Q14500 | ATP-sensitive inward rectifier potassium channel 12 | chr17 | GO:0022832 | Not Cancer Driver | No | 248 | 0.573 | 50 | 27 | 0.54 | 0 |
| KCNJ13_ENST00000410029 | KCNJ13 | O60928 | Inward rectifier potassium channel 13 | chr2 | GO:0022832 | Not Cancer Driver | No | 39 | 0.108 | 44 | 3 | 0.068 | 3 |
| KCNJ14_ENST00000342291 | KCNJ14 | Q9UNX9 | ATP-sensitive inward rectifier potassium channel 14 | chr19 | GO:0022832 | Not Cancer Driver | No | 56 | 0.128 | 73 | 10 | 0.137 | 0 |
| KCNJ15_ENST00000398934 | KCNJ15 | Q99712 | ATP-sensitive inward rectifier potassium channel 15 | chr21 | GO:0022832 | Not Cancer Driver | No | 85 | 0.227 | 12 | 2 | 0.167 | 0 |
| KCNJ16_ENST00000283936 | KCNJ16 | Q9NPI9 | Inward rectifier potassium channel 16 | chr17 | GO:0022832 | Not Cancer Driver | No | 88 | 0.211 | 38 | 8 | 0.211 | 5 |
| KCNJ2_ENST00000535240 | KCNJ2 | P63252 | Inward rectifier potassium channel 2 | chr17 | GO:0022832 | Not Cancer Driver | No | 103 | 0.241 | 49 | 11 | 0.224 | 12 |
| KCNJ3 | KCNJ3 | P48549 | G protein-activated inward rectifier potassium channel 1 | chr2 | GO:0022832 | Not Cancer Driver | No | 189 | 0.377 | 162 | 64 | 0.395 | 0 |
| KCNJ4 | KCNJ4 | P48050 | Inward rectifier potassium channel 4 | chr22 | GO:0022832 | Not Cancer Driver | No | 103 | 0.231 | 62 | 16 | 0.258 | 0 |
| KCNJ5_ENST00000533599 | KCNJ5 | P48544 | G protein-activated inward rectifier potassium channel 4 | chr11 | GO:0022832 | Census | Yes | 87 | 0.208 | 51 | 6 | 0.118 | 6 |
| KCNJ6_ENST00000645093 | KCNJ6 | P48051 | G protein-activated inward rectifier potassium channel 2 | chr21 | GO:0022832 | Not Cancer Driver | No | 106 | 0.251 | 75 | 13 | 0.173 | 1 |
| KCNJ8 | KCNJ8 | Q15842 | ATP-sensitive inward rectifier potassium channel 8 | chr12 | GO:0022832 | Not Cancer Driver | No | 99 | 0.233 | 68 | 22 | 0.324 | 1 |
| KCNJ9 | KCNJ9 | Q92806 | G protein-activated inward rectifier potassium channel 3 | chr1 | GO:0022832 | Not Cancer Driver | No | 47 | 0.12 | 67 | 1 | 0.015 | 0 |
| KCNK1 | KCNK1 | O00180 | Potassium channel subfamily K member 1 | chr1 | GO:0022832 | Not Cancer Driver | No | 65 | 0.193 | 21 | 4 | 0.19 | 0 |
| KCNK18 | KCNK18 | Q7Z418 | Potassium channel subfamily K member 18 | chr10 | GO:0022832 | Not Cancer Driver | No | 103 | 0.268 | 7 | 0 | 0.0 | 0 |
| KCNK2 | KCNK2 | O95069 | Potassium channel subfamily K member 2 | chr1 | GO:0022832 | Not Cancer Driver | No | 109 | 0.256 | 40 | 10 | 0.25 | 0 |
| KCNK3 | KCNK3 | O14649 | Potassium channel subfamily K member 3 | chr2 | GO:0022832 | Not Cancer Driver | No | 54 | 0.137 | 60 | 7 | 0.117 | 6 |
| KCNK6 | KCNK6 | Q9Y257 | Potassium channel subfamily K member 6 | chr19 | GO:0022832 | Not Cancer Driver | No | 39 | 0.125 | 22 | 4 | 0.182 | 0 |
| KCNN1 | KCNN1 | Q92952 | Small conductance calcium-activated potassium channel protein 1 | chr19 | GO:0022832 | Not Cancer Driver | No | 83 | 0.153 | 192 | 19 | 0.099 | 0 |
| KCNN2 | KCNN2 | Q9H2S1 | Small conductance calcium-activated potassium channel protein 2 | chr5 | GO:0022832 | Not Cancer Driver | No | 112 | 0.193 | 175 | 33 | 0.189 | 0 |
| KCNN3_ENST00000271915 | KCNN3 | Q9UGI6 | Small conductance calcium-activated potassium channel protein 3 | chr1 | GO:0022832 | Not Cancer Driver | No | 135 | 0.185 | 302 | 56 | 0.185 | 3 |
| KCNQ1 | KCNQ1 | P51787 | Potassium voltage-gated channel subfamily KQT member 1 | chr11 | GO:0022832 | Not Cancer Driver | No | 78 | 0.115 | 219 | 20 | 0.091 | 132 |
| KCNT1_ENST00000488444 | KCNT1 | Q5JUK3 | Potassium channel subfamily T member 1 | chr9 | GO:0022832 | Not Cancer Driver | No | 187 | 0.152 | 328 | 31 | 0.095 | 12 |
| KCNT2 | KCNT2 | Q6UVM3 | Potassium channel subfamily T member 2 | chr1 | GO:0022832 | Not Cancer Driver | No | 353 | 0.311 | 245 | 89 | 0.363 | 1 |
| PKD2 | PKD2 | Q13563 | Polycystin-2 | chr4 | GO:0022832 | Not Cancer Driver | No | 113 | 0.117 | 375 | 35 | 0.093 | 10 |
| PTK2B_ENST00000346049 | PTK2B | Q14289 | Protein-tyrosine kinase 2-beta | chr8 | GO:0022832 | Not Cancer Driver | No | 161 | 0.16 | 261 | 37 | 0.142 | 0 |
| SLC17A3_ENST00000360657 | SLC17A3 | O00476 | Sodium-dependent phosphate transport protein 4 | chr6 | GO:0022832 | Not Cancer Driver | No | 97 | 0.231 | 26 | 6 | 0.231 | 0 |
| TMEM266 | TMEM266 | Q2M3C6 | Transmembrane protein 266 | chr15 | GO:0022832 | Not Cancer Driver | No | 77 | 0.145 | 239 | 28 | 0.117 | 0 |
| TSPOAP1 | TSPOAP1 | O95153 | Peripheral-type benzodiazepine receptor-associated protein 1 | chr17 | GO:0022832 | Not Cancer Driver | No | 268 | 0.144 | 1522 | 213 | 0.14 | 0 |
| VDAC1_ENST00000395047 | VDAC1 | P21796 | Voltage-dependent anion-selective channel protein 1 | chr5 | GO:0022832 | Not Cancer Driver | No | 38 | 0.134 | 36 | 4 | 0.111 | 0 |
| VDAC2_ENST00000543351 | VDAC2 | P45880 | Voltage-dependent anion-selective channel protein 2 | chr10 | GO:0022832 | Not Cancer Driver | No | 35 | 0.119 | 9 | 1 | 0.111 | 0 |
| VDAC3_ENST00000022615 | VDAC3 | Q9Y277 | Voltage-dependent anion-selective channel protein 3 | chr8 | GO:0022832 | Not Cancer Driver | No | 24 | 0.085 | 0 | 0 | 0.0 | 0 |