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Total number of protein in "GO:0022409" GO term:  224

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ADA ADA P00813 Adenosine deaminase chr20 GO:0022409 Not Cancer Driver No 50 0.138 44 9 0.205 27
ADAM19_ENST00000517905 ADAM19 Q9H013 Disintegrin and metalloproteinase domain-containing protein 19 chr5 GO:0022409 Not Cancer Driver No 172 0.18 370 77 0.208 0
ADAM8 ADAM8 P78325 Disintegrin and metalloproteinase domain-containing protein 8 chr10 GO:0022409 Not Cancer Driver No 82 0.1 230 13 0.057 0
AFDN_ENST00000447894 AFDN P55196 Afadin chr6 GO:0022409 Census Yes 248 0.136 1247 180 0.144 0
AGER_ENST00000375076 AGER Q15109 Advanced glycosylation end product-specific receptor chr6 GO:0022409 Not Cancer Driver No 31 0.077 297 21 0.071 0
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:0022409 Census, Compendium Yes 108 0.225 158 24 0.152 4
ALOX5 ALOX5 P09917 Polyunsaturated fatty acid 5-lipoxygenase chr10 GO:0022409 Not Cancer Driver No 129 0.191 16 2 0.125 0
AMBRA1_ENST00000458649 AMBRA1 Q9C0C7 Activating molecule in BECN1-regulated autophagy protein 1 chr11 GO:0022409 Not Cancer Driver No 173 0.133 788 103 0.131 0
ANK3 ANK3 Q12955 Ankyrin-3 chr10 GO:0022409 Not Cancer Driver No 860 0.196 3054 579 0.19 0
ANXA1_ENST00000257497 ANXA1 P04083 Annexin A1 chr9 GO:0022409 Not Cancer Driver No 59 0.171 61 12 0.197 0
AP3B1 AP3B1 O00203 AP-3 complex subunit beta-1 chr5 GO:0022409 Not Cancer Driver No 126 0.115 316 31 0.098 1
AP3D1_ENST00000345016 AP3D1 O14617 AP-3 complex subunit delta-1 chr19 GO:0022409 Not Cancer Driver No 138 0.12 404 59 0.146 0
BCL6_ENST00000232014 BCL6 P41182 B-cell lymphoma 6 protein chr3 GO:0022409 Census, Compendium Yes 134 0.19 328 67 0.204 0
BMP7 BMP7 P18075 Bone morphogenetic protein 7 chr20 GO:0022409 Not Cancer Driver No 91 0.211 69 18 0.261 0
BTN2A2 BTN2A2 Q8WVV5 Butyrophilin subfamily 2 member A2 chr6 GO:0022409 Not Cancer Driver No 92 0.176 24 2 0.083 0
CARD11 CARD11 Q9BXL7 Caspase recruitment domain-containing protein 11 chr7 GO:0022409 Census, Compendium Yes 303 0.263 530 140 0.264 5
CAV1 CAV1 Q03135 Caveolin-1 chr7 GO:0022409 Not Cancer Driver No 30 0.169 2 0 0.0 0
CBFB_ENST00000290858 CBFB Q13951 Core-binding factor subunit beta chr16 GO:0022409 Census, Compendium Yes 39 0.214 94 17 0.181 0
CCL19 CCL19 Q99731 C-C motif chemokine 19 chr9 GO:0022409 Not Cancer Driver No 10 0.102 7 0 0.0 0
CCL21 CCL21 O00585 C-C motif chemokine 21 chr9 GO:0022409 Not Cancer Driver No 14 0.104 59 6 0.102 0
CCR2_ENST00000400888 CCR2 P41597 C-C chemokine receptor type 2 chr3 GO:0022409 Not Cancer Driver No 81 0.217 23 1 0.043 0
CCR7 CCR7 P32248 C-C chemokine receptor type 7 chr17 GO:0022409 Census, Compendium Yes 50 0.132 0 0 0.0 0
CD160_ENST00000369288 CD160 O95971 CD160 antigen chr1 GO:0022409 Not Cancer Driver No 20 0.11 2 0 0.0 0
CD274 CD274 Q9NZQ7 Programmed cell death 1 ligand 1 chr9 GO:0022409 Census Yes 29 0.1 54 9 0.167 0
CD28 CD28 P10747 T-cell-specific surface glycoprotein CD28 chr2 GO:0022409 Census Yes 42 0.191 18 10 0.556 0
CD3E CD3E P07766 T-cell surface glycoprotein CD3 epsilon chain chr11 GO:0022409 Not Cancer Driver No 28 0.135 72 12 0.167 0
CD40LG CD40LG P29965 CD40 ligand chrX GO:0022409 Not Cancer Driver No 56 0.215 24 7 0.292 32
CD44 CD44 P16070 CD44 antigen chr11 GO:0022409 Not Cancer Driver No 75 0.101 542 60 0.111 0
CD46_ENST00000358170 CD46 P15529 Membrane cofactor protein chr1 GO:0022409 Not Cancer Driver No 53 0.135 52 4 0.077 5
CD47 CD47 Q08722 Leukocyte surface antigen CD47 chr3 GO:0022409 Not Cancer Driver No 37 0.115 0 0 0.0 0
CD5 CD5 P06127 T-cell surface glycoprotein CD5 chr11 GO:0022409 Not Cancer Driver No 67 0.135 146 19 0.13 0
CD55_ENST00000367064 CD55 P08174 Complement decay-accelerating factor chr1 GO:0022409 Not Cancer Driver No 45 0.118 128 13 0.102 1
CD80_ENST00000478182 CD80 P33681 T-lymphocyte activation antigen CD80 chr3 GO:0022409 Not Cancer Driver No 50 0.174 26 5 0.192 0
CD81 CD81 P60033 CD81 antigen chr11 GO:0022409 Not Cancer Driver No 28 0.119 0 0 0.0 0
CD83 CD83 Q01151 CD83 antigen chr6 GO:0022409 Not Cancer Driver No 24 0.117 48 8 0.167 0
CD86 CD86 P42081 T-lymphocyte activation antigen CD86 chr3 GO:0022409 Not Cancer Driver No 90 0.274 56 18 0.321 0
CEACAM6 CEACAM6 P40199 Carcinoembryonic antigen-related cell adhesion molecule 6 chr19 GO:0022409 Not Cancer Driver No 63 0.183 110 19 0.173 0
CHST2 CHST2 Q9Y4C5 Carbohydrate sulfotransferase 2 chr3 GO:0022409 Not Cancer Driver No 98 0.185 136 11 0.081 0
CHST4_ENST00000539698 CHST4 Q8NCG5 Carbohydrate sulfotransferase 4 chr16 GO:0022409 Not Cancer Driver No 59 0.153 7 0 0.0 0
CITED2_ENST00000367651 CITED2 Q99967 Cbp/p300-interacting transactivator 2 chr6 GO:0022409 Not Cancer Driver No 23 0.085 230 18 0.078 0
CR1_ENST00000367053 CR1 P17927 Complement receptor type 1 chr1 GO:0022409 Compendium Yes 383 0.188 151 42 0.278 0
CSK_ENST00000439220 CSK P41240 Tyrosine-protein kinase CSK chr15 GO:0022409 Not Cancer Driver No 41 0.091 18 1 0.056 0
CTSG CTSG P08311 Cathepsin G chr14 GO:0022409 Not Cancer Driver No 65 0.255 80 29 0.362 0
CX3CL1 CX3CL1 P78423 Fractalkine chr16 GO:0022409 Not Cancer Driver No 66 0.166 259 44 0.17 0
CXCL13 CXCL13 O43927 C-X-C motif chemokine 13 chr4 GO:0022409 Not Cancer Driver No 11 0.101 0 0 0.0 0
DENND6A DENND6A Q8IWF6 Protein DENND6A chr3 GO:0022409 Not Cancer Driver No 54 0.089 69 2 0.029 0
DMTN_ENST00000358242 DMTN Q08495 Dematin chr8 GO:0022409 Not Cancer Driver No 53 0.131 348 46 0.132 0
DOCK8 DOCK8 Q8NF50 Dedicator of cytokinesis protein 8 chr9 GO:0022409 Not Cancer Driver No 321 0.153 312 60 0.192 1
DPP4 DPP4 P27487 Dipeptidyl peptidase 4 chr2 GO:0022409 Not Cancer Driver No 151 0.197 8 1 0.125 0
DUSP10 DUSP10 Q9Y6W6 Dual specificity protein phosphatase 10 chr1 GO:0022409 Not Cancer Driver No 81 0.168 135 24 0.178 0
EBI3 EBI3 Q14213 Interleukin-27 subunit beta chr19 GO:0022409 Not Cancer Driver No 32 0.14 10 1 0.1 0
EFNB1 EFNB1 P98172 Ephrin-B1 chrX GO:0022409 Not Cancer Driver No 46 0.133 126 14 0.111 19
EFNB2_ENST00000245323 EFNB2 P52799 Ephrin-B2 chr13 GO:0022409 Not Cancer Driver No 42 0.126 97 15 0.155 0
EFNB3 EFNB3 Q15768 Ephrin-B3 chr17 GO:0022409 Not Cancer Driver No 45 0.132 183 22 0.12 0
EGR3 EGR3 Q06889 Early growth response protein 3 chr8 GO:0022409 Not Cancer Driver No 60 0.155 252 46 0.183 0
ELANE_ENST00000263621 ELANE P08246 Neutrophil elastase chr19 GO:0022409 Not Cancer Driver No 39 0.146 18 3 0.167 89
EMILIN2 EMILIN2 Q9BXX0 EMILIN-2 chr18 GO:0022409 Not Cancer Driver No 158 0.15 617 94 0.152 0
EPO EPO P01588 Erythropoietin chr7 GO:0022409 Not Cancer Driver No 27 0.14 9 1 0.111 1
ETS1_ENST00000319397 ETS1 P14921 Protein C-ets-1 chr11 GO:0022409 Not Cancer Driver No 68 0.154 78 9 0.115 0
F11R F11R Q9Y624 Junctional adhesion molecule A chr1 GO:0022409 Not Cancer Driver No 47 0.157 72 15 0.208 0
FADD FADD Q13158 FAS-associated death domain protein chr11 GO:0022409 Not Cancer Driver No 26 0.125 45 10 0.222 1
FAM49B_ENST00000519540 CYRIB Q9NUQ9 CYFIP-related Rac1 interactor B chr8 GO:0022409 Not Cancer Driver No 53 0.164 78 11 0.141 0
FGA FGA P02671 Fibrinogen alpha chain chr4 GO:0022409 Not Cancer Driver No 245 0.283 522 149 0.285 7
FGB FGB P02675 Fibrinogen beta chain chr4 GO:0022409 Not Cancer Driver No 89 0.181 143 29 0.203 7
FGG FGG P02679 Fibrinogen gamma chain chr4 GO:0022409 Not Cancer Driver No 81 0.179 53 8 0.151 8
FLOT1 FLOT1 O75955 Flotillin-1 chr6 GO:0022409 Not Cancer Driver No 43 0.101 122 15 0.123 0
FLOT2 FLOT2 Q14254 Flotillin-2 chr17 GO:0022409 Not Cancer Driver No 56 0.131 20 3 0.15 0
FOXA1 FOXA1 P55317 Hepatocyte nuclear factor 3-alpha chr14 GO:0022409 Census, Compendium Yes 100 0.212 295 53 0.18 0
FOXA2_ENST00000377115 FOXA2 Q9Y261 Hepatocyte nuclear factor 3-beta chr20 GO:0022409 Compendium Yes 70 0.153 258 34 0.132 0
FOXO3 FOXO3 O43524 Forkhead box protein O3 chr6 GO:0022409 Census, Compendium Yes 70 0.104 595 68 0.114 0
FOXP3 FOXP3 Q9BZS1 Forkhead box protein P3 chrX GO:0022409 Not Cancer Driver No 38 0.088 186 16 0.086 10
FSTL3 FSTL3 O95633 Follistatin-related protein 3 chr19 GO:0022409 Census Yes 17 0.065 28 2 0.071 0
FUT3_ENST00000589620 FUT3 P21217 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT3 chr19 GO:0022409 Not Cancer Driver No 77 0.213 33 9 0.273 0
FUT4 FUT4 P22083 Alpha-(1,3)-fucosyltransferase 4 chr11 GO:0022409 Not Cancer Driver No 49 0.092 193 9 0.047 0
FUT7 FUT7 Q11130 Alpha-(1,3)-fucosyltransferase 7 chr9 GO:0022409 Not Cancer Driver No 28 0.082 25 3 0.12 0
FYN FYN P06241 Tyrosine-protein kinase Fyn chr6 GO:0022409 Not Cancer Driver No 92 0.171 70 13 0.186 0
GCNT2_ENST00000379597 GCNT2 Q8N0V5 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase chr6 GO:0022409 Not Cancer Driver No 40 0.1 3 0 0.0 0
GLI2_ENST00000361492 GLI2 P10070 Zinc finger protein GLI2 chr2 GO:0022409 Not Cancer Driver No 287 0.181 1403 244 0.174 2
GLI3 GLI3 P10071 Transcriptional activator GLI3 chr7 GO:0022409 Not Cancer Driver No 385 0.244 1352 327 0.242 7
GP6_ENST00000417454 GP6 Q9HCN6 Platelet glycoprotein VI chr19 GO:0022409 Not Cancer Driver No 57 0.168 122 21 0.172 2
GPAM GPAM Q9HCL2 Glycerol-3-phosphate acyltransferase 1, mitochondrial chr10 GO:0022409 Not Cancer Driver No 108 0.13 83 7 0.084 0
HAS2 HAS2 Q92819 Hyaluronan synthase 2 chr8 GO:0022409 Not Cancer Driver No 100 0.181 17 7 0.412 0
HHLA2_ENST00000489514 HHLA2 Q9UM44 HERV-H LTR-associating protein 2 chr3 GO:0022409 Not Cancer Driver No 85 0.205 57 10 0.175 0
HLA-A_ENST00000376809 HLA-A P04439 HLA class I histocompatibility antigen, A alpha chain chr6 GO:0022409 Census, Compendium Yes 128 0.351 125 60 0.48 0
HLA-DMB HLA-DMB P28068 HLA class II histocompatibility antigen, DM beta chain chr6 GO:0022409 Not Cancer Driver No 41 0.156 41 9 0.22 0
HLA-DRA HLA-DRA P01903 HLA class II histocompatibility antigen, DR alpha chain chr6 GO:0022409 Not Cancer Driver No 52 0.205 12 1 0.083 0
HLA-DRB1 HLA-DRB1 P01911 HLA class II histocompatibility antigen, DRB1 beta chain chr6 GO:0022409 Not Cancer Driver No 48 0.18 12 1 0.083 0
HLA-E HLA-E P13747 HLA class I histocompatibility antigen, alpha chain E chr6 GO:0022409 Not Cancer Driver No 63 0.176 138 39 0.283 0
HLA-G_ENST00000360323 HLA-G P17693 HLA class I histocompatibility antigen, alpha chain G chr6 GO:0022409 Not Cancer Driver No 94 0.278 85 22 0.259 0
HLX HLX Q14774 H2.0-like homeobox protein chr1 GO:0022409 Not Cancer Driver No 107 0.219 412 98 0.238 0
HMGB1_ENST00000405805 HMGB1 P09429 High mobility group protein B1 chr13 GO:0022409 Not Cancer Driver No 25 0.116 203 20 0.099 0
HSPH1_ENST00000320027 HSPH1 Q92598 Heat shock protein 105 kDa chr13 GO:0022409 Not Cancer Driver No 103 0.12 323 42 0.13 0
ICOS ICOS Q9Y6W8 Inducible T-cell costimulator chr2 GO:0022409 Not Cancer Driver No 36 0.181 0 0 0.0 0
ICOSLG_ENST00000407780 ICOSLG O75144 ICOS ligand chr21 GO:0022409 Not Cancer Driver No 25 0.083 30 2 0.067 0
IFNG IFNG P01579 Interferon gamma chr12 GO:0022409 Not Cancer Driver No 51 0.307 23 6 0.261 0
IGF1_ENST00000307046 IGF1 P05019 Insulin-like growth factor I chr12 GO:0022409 Not Cancer Driver No 45 0.231 87 23 0.264 0
IGF2_ENST00000641326 IGF2 P01344 Insulin-like growth factor II chr11 GO:0022409 Not Cancer Driver No 39 0.217 44 12 0.273 0
IGFBP2 IGFBP2 P18065 Insulin-like growth factor-binding protein 2 chr2 GO:0022409 Not Cancer Driver No 32 0.098 171 24 0.14 0
IHH IHH Q14623 Indian hedgehog protein chr2 GO:0022409 Not Cancer Driver No 58 0.141 111 15 0.135 6
IL10 IL10 P22301 Interleukin-10 chr1 GO:0022409 Not Cancer Driver No 19 0.107 23 1 0.043 0
IL12B IL12B P29460 Interleukin-12 subunit beta chr5 GO:0022409 Not Cancer Driver No 48 0.146 42 2 0.048 0
IL12RB1_ENST00000593993 IL12RB1 P42701 Interleukin-12 receptor subunit beta-1 chr19 GO:0022409 Not Cancer Driver No 108 0.163 207 38 0.184 1
IL18 IL18 Q14116 Interleukin-18 chr11 GO:0022409 Not Cancer Driver No 19 0.098 16 3 0.188 0
IL1A IL1A P01583 Interleukin-1 alpha chr2 GO:0022409 Not Cancer Driver No 30 0.111 35 6 0.171 0
IL1B IL1B P01584 Interleukin-1 beta chr2 GO:0022409 Not Cancer Driver No 39 0.145 16 3 0.188 0
IL2 IL2 P60568 Interleukin-2 chr4 GO:0022409 Census Yes 24 0.157 6 1 0.167 0
IL23A IL23A Q9NPF7 Interleukin-23 subunit alpha chr12 GO:0022409 Not Cancer Driver No 15 0.079 42 3 0.071 0
IL23R IL23R Q5VWK5 Interleukin-23 receptor chr1 GO:0022409 Not Cancer Driver No 70 0.111 117 19 0.162 0
IL27RA IL27RA Q6UWB1 Interleukin-27 receptor subunit alpha chr19 GO:0022409 Not Cancer Driver No 91 0.143 167 23 0.138 0
IL2RA IL2RA P01589 Interleukin-2 receptor subunit alpha chr10 GO:0022409 Not Cancer Driver No 51 0.188 131 29 0.221 2
IL4I1_ENST00000391826 IL4I1 Q96RQ9 L-amino-acid oxidase chr19 GO:0022409 Not Cancer Driver No 65 0.115 136 14 0.103 0
IL4R_ENST00000543915 IL4R P24394 Interleukin-4 receptor subunit alpha chr16 GO:0022409 Not Cancer Driver No 133 0.161 420 64 0.152 0
IL6 IL6 P05231 Interleukin-6 chr7 GO:0022409 Not Cancer Driver No 35 0.165 58 7 0.121 0
IL6ST_ENST00000336909 IL6ST P40189 Interleukin-6 receptor subunit beta chr5 GO:0022409 Census, Compendium Yes 102 0.111 315 40 0.127 2
IL7R IL7R P16871 Interleukin-7 receptor subunit alpha chr5 GO:0022409 Census, Compendium Yes 177 0.386 88 48 0.545 1
IRAK1 IRAK1 P51617 Interleukin-1 receptor-associated kinase 1 chrX GO:0022409 Compendium Yes 71 0.1 337 39 0.116 0
ITGA4 ITGA4 P13612 Integrin alpha-4 chr2 GO:0022409 Not Cancer Driver No 254 0.246 97 27 0.278 0
ITGB2_ENST00000355153 ITGB2 P05107 Integrin beta-2 chr21 GO:0022409 Not Cancer Driver No 147 0.191 59 9 0.153 15
ITPKB_ENST00000272117 ITPKB P27987 Inositol-trisphosphate 3-kinase B chr1 GO:0022409 Not Cancer Driver No 148 0.156 719 119 0.166 0
JAK1 JAK1 P23458 Tyrosine-protein kinase JAK1 chr1 GO:0022409 Census, Compendium Yes 147 0.127 120 7 0.058 2
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 GO:0022409 Census, Compendium Yes 136 0.12 59 5 0.085 5
JAK3 JAK3 P52333 Tyrosine-protein kinase JAK3 chr19 GO:0022409 Census, Compendium Yes 167 0.149 63 10 0.159 7
KIF26B KIF26B Q2KJY2 Kinesin-like protein KIF26B chr1 GO:0022409 Not Cancer Driver No 369 0.175 1412 198 0.14 0
KIFAP3 KIFAP3 Q92845 Kinesin-associated protein 3 chr1 GO:0022409 Not Cancer Driver No 116 0.146 71 10 0.141 0
KLRK1 KLRK1 P26718 NKG2-D type II integral membrane protein chr12 GO:0022409 Not Cancer Driver No 38 0.176 0 0 0.0 0
LCK LCK P06239 Tyrosine-protein kinase Lck chr1 GO:0022409 Census Yes 86 0.169 94 13 0.138 1
LEF1 LEF1 Q9UJU2 Lymphoid enhancer-binding factor 1 chr4 GO:0022409 Census Yes 64 0.16 370 57 0.154 0
LGALS1 LGALS1 P09382 Galectin-1 chr22 GO:0022409 Not Cancer Driver No 16 0.119 0 0 0.0 0
LGALS9 LGALS9 O00182 Galectin-9 chr17 GO:0022409 Not Cancer Driver No 54 0.152 65 16 0.246 0
LILRB1_ENST00000396331 LILRB1 Q8NHL6 Leukocyte immunoglobulin-like receptor subfamily B member 1 chr19 GO:0022409 Not Cancer Driver No 203 0.312 291 97 0.333 0
LILRB2_ENST00000314446 LILRB2 Q8N423 Leukocyte immunoglobulin-like receptor subfamily B member 2 chr19 GO:0022409 Not Cancer Driver No 148 0.248 235 50 0.213 0
LILRB4 LILRB4 Q8NHJ6 Leukocyte immunoglobulin-like receptor subfamily B member 4 chr19 GO:0022409 Not Cancer Driver No 162 0.362 277 115 0.415 0
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 GO:0022409 Census Yes 95 0.186 84 12 0.143 0
MAGI1 MAGI1 Q96QZ7 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 chr3 GO:0022409 Not Cancer Driver No 260 0.174 1212 220 0.182 0
MALT1 MALT1 Q9UDY8 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 chr18 GO:0022409 Census, Compendium Yes 75 0.091 139 12 0.086 1
MAP3K8_ENST00000542547 MAP3K8 P41279 Mitogen-activated protein kinase kinase kinase 8 chr10 GO:0022409 Not Cancer Driver No 58 0.124 109 10 0.092 0
MDK_ENST00000407067 MDK P21741 Midkine chr11 GO:0022409 Not Cancer Driver No 15 0.105 20 2 0.1 0
MEGF10_ENST00000503335 MEGF10 Q96KG7 Multiple epidermal growth factor-like domains protein 10 chr5 GO:0022409 Not Cancer Driver No 216 0.189 204 42 0.206 2
MMRN1 MMRN1 Q13201 Multimerin-1 chr4 GO:0022409 Not Cancer Driver No 241 0.196 373 75 0.201 0
MYB_ENST00000367814 MYB P10242 Transcriptional activator Myb chr6 GO:0022409 Census Yes 82 0.128 528 69 0.131 0
MYO10 MYO10 Q9HD67 Unconventional myosin-X chr5 GO:0022409 Not Cancer Driver No 296 0.144 418 59 0.141 0
NCKAP1L NCKAP1L P55160 Nck-associated protein 1-like chr12 GO:0022409 Not Cancer Driver No 247 0.219 51 10 0.196 4
NFAT5_ENST00000354436 NFAT5 O94916 Nuclear factor of activated T-cells 5 chr16 GO:0022409 Not Cancer Driver No 142 0.093 1307 119 0.091 0
NFKBID NFKBID Q8NI38 NF-kappa-B inhibitor delta chr19 GO:0022409 Not Cancer Driver No 47 0.15 124 20 0.161 0
NFKBIZ NFKBIZ Q9BYH8 NF-kappa-B inhibitor zeta chr3 GO:0022409 Not Cancer Driver No 96 0.134 443 53 0.12 0
NKAP NKAP Q8N5F7 NF-kappa-B-activating protein chrX GO:0022409 Not Cancer Driver No 80 0.193 409 77 0.188 3
NLRP3_ENST00000391828 NLRP3 Q96P20 NACHT, LRR and PYD domains-containing protein 3 chr1 GO:0022409 Not Cancer Driver No 339 0.327 64 33 0.516 37
NOD2 NOD2 Q9HC29 Nucleotide-binding oligomerization domain-containing protein 2 chr16 GO:0022409 Not Cancer Driver No 169 0.163 40 4 0.1 15
NODAL NODAL Q96S42 Nodal homolog chr10 GO:0022409 Not Cancer Driver No 40 0.115 34 8 0.235 4
NR4A3_ENST00000395097 NR4A3 Q92570 Nuclear receptor subfamily 4 group A member 3 chr9 GO:0022409 Census Yes 83 0.133 298 37 0.124 0
PCK1 PCK1 P35558 Phosphoenolpyruvate carboxykinase, cytosolic [GTP] chr20 GO:0022409 Not Cancer Driver No 142 0.228 110 28 0.255 1
PDCD1LG2 PDCD1LG2 Q9BQ51 Programmed cell death 1 ligand 2 chr9 GO:0022409 Census, Compendium Yes 33 0.121 41 13 0.317 0
PDPN_ENST00000621990 PDPN Q86YL7 Podoplanin chr1 GO:0022409 Not Cancer Driver No 37 0.228 96 24 0.25 0
PIEZO1 PIEZO1 Q92508 Piezo-type mechanosensitive ion channel component 1 chr16 GO:0022409 Not Cancer Driver No 122 0.048 471 26 0.055 12
PIK3CA PIK3CA P42336 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform chr3 GO:0022409 Census, Compendium Yes 1669 1.563 38 11 0.289 30
PLAUR PLAUR Q03405 Urokinase plasminogen activator surface receptor chr19 GO:0022409 Not Cancer Driver No 49 0.146 18 5 0.278 0
PNP PNP P00491 Purine nucleoside phosphorylase chr14 GO:0022409 Not Cancer Driver No 38 0.131 29 2 0.069 5
PODXL PODXL O00592 Podocalyxin chr7 GO:0022409 Not Cancer Driver No 69 0.124 432 56 0.13 0
PRKCQ PRKCQ Q04759 Protein kinase C theta type chr10 GO:0022409 Not Cancer Driver No 147 0.208 28 9 0.321 0
PRKCZ PRKCZ Q05513 Protein kinase C zeta type chr1 GO:0022409 Not Cancer Driver No 70 0.118 116 11 0.095 0
PTAFR_ENST00000305392 PTAFR P25105 Platelet-activating factor receptor chr1 GO:0022409 Not Cancer Driver No 42 0.123 0 0 0.0 0
PTPN11_ENST00000351677 PTPN11 Q06124 Tyrosine-protein phosphatase non-receptor type 11 chr12 GO:0022409 Census, Compendium Yes 129 0.218 260 38 0.146 60
PTPN22 PTPN22 Q9Y2R2 Tyrosine-protein phosphatase non-receptor type 22 chr1 GO:0022409 Not Cancer Driver No 141 0.175 364 62 0.17 4
PTPN23 PTPN23 Q9H3S7 Tyrosine-protein phosphatase non-receptor type 23 chr3 GO:0022409 Not Cancer Driver No 147 0.09 796 71 0.089 2
PTPN6_ENST00000318974 PTPN6 P29350 Tyrosine-protein phosphatase non-receptor type 6 chr12 GO:0022409 Census, Compendium Yes 73 0.123 192 25 0.13 0
PTPRC PTPRC P08575 Receptor-type tyrosine-protein phosphatase C chr1 GO:0022409 Census, Compendium Yes 315 0.241 462 107 0.232 0
PTPRU PTPRU Q92729 Receptor-type tyrosine-protein phosphatase U chr1 GO:0022409 Not Cancer Driver No 248 0.172 325 64 0.197 0
PYCARD PYCARD Q9ULZ3 Apoptosis-associated speck-like protein containing a CARD chr16 GO:0022409 Not Cancer Driver No 16 0.082 39 4 0.103 0
RARA RARA P10276 Retinoic acid receptor alpha chr17 GO:0022409 Census, Compendium Yes 70 0.152 167 14 0.084 0
RASAL3 RASAL3 Q86YV0 RAS protein activator like-3 chr19 GO:0022409 Not Cancer Driver No 114 0.113 536 68 0.127 0
RASGRP1 RASGRP1 O95267 RAS guanyl-releasing protein 1 chr15 GO:0022409 Not Cancer Driver No 96 0.12 191 12 0.063 1
RELA RELA Q04206 Transcription factor p65 chr11 GO:0022409 Compendium Yes 75 0.136 400 48 0.12 0
RHOA RHOA P61586 Transforming protein RhoA chr3 GO:0022409 Census, Compendium Yes 99 0.513 46 13 0.283 2
RIPK2 RIPK2 O43353 Receptor-interacting serine/threonine-protein kinase 2 chr8 GO:0022409 Not Cancer Driver No 63 0.117 143 20 0.14 0
RNASE10 RNASE10 Q5GAN6 Inactive ribonuclease-like protein 10 chr14 GO:0022409 Not Cancer Driver No 48 0.222 68 20 0.294 0
RPS3_ENST00000527446 RPS3 P23396 40S ribosomal protein S3 chr11 GO:0022409 Not Cancer Driver No 22 0.091 48 4 0.083 0
RUNX1_ENST00000344691 RUNX1 Q01196 Runt-related transcription factor 1 chr21 GO:0022409 Census, Compendium Yes 81 0.179 360 58 0.161 2
RUNX3_ENST00000308873 RUNX3 Q13761 Runt-related transcription factor 3 chr1 GO:0022409 Not Cancer Driver No 59 0.142 331 45 0.136 0
SART1 SART1 O43290 U4/U6.U5 tri-snRNP-associated protein 1 chr11 GO:0022409 Not Cancer Driver No 71 0.089 685 63 0.092 0
SASH3 SASH3 O75995 SAM and SH3 domain-containing protein 3 chrX GO:0022409 Not Cancer Driver No 59 0.155 327 49 0.15 0
SELE SELE P16581 E-selectin chr1 GO:0022409 Not Cancer Driver No 137 0.225 12 0 0.0 0
SELP SELP P16109 P-selectin chr1 GO:0022409 Not Cancer Driver No 226 0.272 14 2 0.143 0
SERPINF2_ENST00000382061 SERPINF2 P08697 Alpha-2-antiplasmin chr17 GO:0022409 Not Cancer Driver No 62 0.126 112 21 0.188 1
SHH SHH Q15465 Sonic hedgehog protein chr7 GO:0022409 Not Cancer Driver No 56 0.121 139 14 0.101 81
SIRPG SIRPG Q9P1W8 Signal-regulatory protein gamma chr20 GO:0022409 Not Cancer Driver No 110 0.284 127 38 0.299 0
SKAP1_ENST00000584924 SKAP1 Q86WV1 Src kinase-associated phosphoprotein 1 chr17 GO:0022409 Not Cancer Driver No 67 0.187 130 27 0.208 0
SLAMF1_ENST00000302035 SLAMF1 Q13291 Signaling lymphocytic activation molecule chr1 GO:0022409 Not Cancer Driver No 82 0.245 64 10 0.156 0
SMAD7 SMAD7 O15105 Mothers against decapentaplegic homolog 7 chr18 GO:0022409 Not Cancer Driver No 40 0.094 139 0 0.0 0
SOCS1 SOCS1 O15524 Suppressor of cytokine signaling 1 chr16 GO:0022409 Census, Compendium Yes 22 0.104 66 3 0.045 2
SOCS5 SOCS5 O75159 Suppressor of cytokine signaling 5 chr2 GO:0022409 Not Cancer Driver No 84 0.157 297 46 0.155 0
SOX12 SOX12 O15370 Transcription factor SOX-12 chr20 GO:0022409 Not Cancer Driver No 20 0.063 307 19 0.062 0
SOX13 SOX13 Q9UN79 Transcription factor SOX-13 chr1 GO:0022409 Not Cancer Driver No 85 0.137 564 77 0.137 0
SOX2 SOX2 P48431 Transcription factor SOX-2 chr3 GO:0022409 Census Yes 39 0.123 312 39 0.125 0
SOX4 SOX4 Q06945 Transcription factor SOX-4 chr6 GO:0022409 Not Cancer Driver No 28 0.059 400 24 0.06 4
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:0022409 Census Yes 53 0.099 130 11 0.085 1
ST3GAL4_ENST00000534083 ST3GAL4 Q11206 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 chr11 GO:0022409 Not Cancer Driver No 31 0.093 3 2 0.667 0
STAT5B STAT5B P51692 Signal transducer and activator of transcription 5B chr17 GO:0022409 Census, Compendium Yes 93 0.118 144 19 0.132 5
SYK_ENST00000375746 SYK P43405 Tyrosine-protein kinase SYK chr9 GO:0022409 Census Yes 96 0.151 131 27 0.206 5
TESPA1 TESPA1 A2RU30 Protein TESPA1 chr12 GO:0022409 Not Cancer Driver No 127 0.244 284 84 0.296 0
TGFBR2_ENST00000295754 TGFBR2 P37173 TGF-beta receptor type-2 chr3 GO:0022409 Census, Compendium Yes 106 0.187 60 16 0.267 25
THY1 THY1 P04216 Thy-1 membrane glycoprotein chr11 GO:0022409 Not Cancer Driver No 24 0.149 5 0 0.0 0
TJP1_ENST00000346128 TJP1 Q07157 Tight junction protein ZO-1 chr15 GO:0022409 Not Cancer Driver No 198 0.113 1350 151 0.112 0
TMIGD2 TMIGD2 Q96BF3 Transmembrane and immunoglobulin domain-containing protein 2 chr19 GO:0022409 Not Cancer Driver No 57 0.202 120 32 0.267 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:0022409 Not Cancer Driver No 24 0.103 45 3 0.067 0
TNFRSF13C TNFRSF13C Q96RJ3 Tumor necrosis factor receptor superfamily member 13C chr22 GO:0022409 Not Cancer Driver No 17 0.092 128 15 0.117 0
TNFRSF14 TNFRSF14 Q92956 Tumor necrosis factor receptor superfamily member 14 chr1 GO:0022409 Census, Compendium Yes 33 0.117 54 8 0.148 0
TNFSF11 TNFSF11 O14788 Tumor necrosis factor ligand superfamily member 11 chr13 GO:0022409 Not Cancer Driver No 52 0.164 56 1 0.018 1
TNFSF13B TNFSF13B Q9Y275 Tumor necrosis factor ligand superfamily member 13B chr13 GO:0022409 Not Cancer Driver No 41 0.144 91 15 0.165 0
TNFSF14 TNFSF14 O43557 Tumor necrosis factor ligand superfamily member 14 chr19 GO:0022409 Not Cancer Driver No 58 0.242 18 1 0.056 0
TNFSF4 TNFSF4 P23510 Tumor necrosis factor ligand superfamily member 4 chr1 GO:0022409 Not Cancer Driver No 28 0.153 1 0 0.0 0
TNFSF9 TNFSF9 P41273 Tumor necrosis factor ligand superfamily member 9 chr19 GO:0022409 Not Cancer Driver No 32 0.126 39 4 0.103 0
TRAF6_ENST00000348124 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 GO:0022409 Not Cancer Driver No 67 0.128 62 7 0.113 0
TYK2 TYK2 P29597 Non-receptor tyrosine-protein kinase TYK2 chr19 GO:0022409 Not Cancer Driver No 148 0.125 213 29 0.136 0
VAV1 VAV1 P15498 Proto-oncogene vav chr19 GO:0022409 Census, Compendium Yes 165 0.195 113 19 0.168 0
VNN1 VNN1 O95497 Pantetheinase chr6 GO:0022409 Not Cancer Driver No 88 0.172 20 5 0.25 0
VSIR VSIR Q9H7M9 V-type immunoglobulin domain-containing suppressor of T-cell activation chr10 GO:0022409 Not Cancer Driver No 52 0.167 135 19 0.141 0
WNT3A WNT3A P56704 Protein Wnt-3a chr1 GO:0022409 Not Cancer Driver No 77 0.219 37 5 0.135 0
WNT5A_ENST00000474267 WNT5A P41221 Protein Wnt-5a chr3 GO:0022409 Not Cancer Driver No 66 0.174 0 0 0.0 2
XCL1 XCL1 P47992 Lymphotactin chr1 GO:0022409 Not Cancer Driver No 28 0.246 35 11 0.314 0
YES1_ENST00000314574 YES1 P07947 Tyrosine-protein kinase Yes chr18 GO:0022409 Not Cancer Driver No 65 0.12 62 10 0.161 0
ZAP70 ZAP70 P43403 Tyrosine-protein kinase ZAP-70 chr2 GO:0022409 Not Cancer Driver No 126 0.204 117 17 0.145 8
ZBTB1 ZBTB1 Q9Y2K1 Zinc finger and BTB domain-containing protein 1 chr14 GO:0022409 Not Cancer Driver No 70 0.098 271 27 0.1 0
ZBTB16_ENST00000392996 ZBTB16 Q05516 Zinc finger and BTB domain-containing protein 16 chr11 GO:0022409 Census, Compendium Yes 131 0.195 268 50 0.187 1
ZBTB7B_ENST00000368426 ZBTB7B O15156 Zinc finger and BTB domain-containing protein 7B chr1 GO:0022409 Compendium Yes 103 0.191 353 70 0.198 0