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Total number of protein in "GO:0021953" GO term:  82

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABT1 ABT1 Q9ULW3 Activator of basal transcription 1 chr6 GO:0021953 Not Cancer Driver No 56 0.206 157 30 0.191 0
AGTPBP1_ENST00000357081 AGTPBP1 Q9UPW5 Cytosolic carboxypeptidase 1 chr9 GO:0021953 Not Cancer Driver No 158 0.129 321 42 0.131 4
ASCL1 ASCL1 P50553 Achaete-scute homolog 1 chr12 GO:0021953 Not Cancer Driver No 33 0.14 182 24 0.132 0
ATP7A ATP7A Q04656 Copper-transporting ATPase 1 chrX GO:0021953 Not Cancer Driver No 228 0.152 171 46 0.269 52
BCL11B BCL11B Q9C0K0 B-cell lymphoma/leukemia 11B chr14 GO:0021953 Census, Compendium Yes 156 0.174 699 114 0.163 2
BLOC1S2 BLOC1S2 Q6QNY1 Biogenesis of lysosome-related organelles complex 1 subunit 2 chr10 GO:0021953 Not Cancer Driver No 17 0.12 34 6 0.176 0
C21orf91 EURL Q9NYK6 Protein EURL homolog chr21 GO:0021953 Not Cancer Driver No 31 0.104 120 15 0.125 0
CBLN1 CBLN1 P23435 Cerebellin-1 chr16 GO:0021953 Not Cancer Driver No 46 0.238 14 2 0.143 0
CEND1 CEND1 Q8N111 Cell cycle exit and neuronal differentiation protein 1 chr11 GO:0021953 Not Cancer Driver No 13 0.087 124 10 0.081 0
CHD5 CHD5 Q8TDI0 Chromodomain-helicase-DNA-binding protein 5 chr1 GO:0021953 Not Cancer Driver No 365 0.187 931 183 0.197 0
CLN8 CLN8 Q9UBY8 Protein CLN8 chr8 GO:0021953 Not Cancer Driver No 45 0.157 16 2 0.125 16
CSF1R CSF1R P07333 Macrophage colony-stimulating factor 1 receptor chr5 GO:0021953 Census Yes 133 0.137 124 17 0.137 20
DLX1 DLX1 P56177 Homeobox protein DLX-1 chr2 GO:0021953 Not Cancer Driver No 25 0.098 183 21 0.115 0
DLX2 DLX2 Q07687 Homeobox protein DLX-2 chr2 GO:0021953 Not Cancer Driver No 46 0.14 262 38 0.145 0
DRAXIN DRAXIN Q8NBI3 Draxin chr1 GO:0021953 Not Cancer Driver No 61 0.175 249 48 0.193 0
DYNC2H1_ENST00000375735 DYNC2H1 Q8NCM8 Cytoplasmic dynein 2 heavy chain 1 chr11 GO:0021953 Not Cancer Driver No 510 0.118 282 15 0.053 34
ELAVL4_ENST00000371821 ELAVL4 P26378 ELAV-like protein 4 chr1 GO:0021953 Not Cancer Driver No 118 0.306 117 34 0.291 0
EMX1 EMX1 Q04741 Homeobox protein EMX1 chr2 GO:0021953 Not Cancer Driver No 26 0.09 162 20 0.123 0
EOMES_ENST00000295743 EOMES O95936 Eomesodermin homolog chr3 GO:0021953 Not Cancer Driver No 82 0.12 436 50 0.115 0
FAIM2 FAIM2 Q9BWQ8 Protein lifeguard 2 chr12 GO:0021953 Not Cancer Driver No 37 0.117 54 11 0.204 0
FOXN4 FOXN4 Q96NZ1 Forkhead box protein N4 chr12 GO:0021953 Not Cancer Driver No 60 0.116 377 34 0.09 0
GATA2_ENST00000487848 GATA2 P23769 Endothelial transcription factor GATA-2 chr3 GO:0021953 Census, Compendium Yes 72 0.15 370 49 0.132 6
GBX1 GBX1 Q14549 Homeobox protein GBX-1 chr7 GO:0021953 Not Cancer Driver No 40 0.11 267 28 0.105 0
GDF7 GDF7 Q7Z4P5 Growth/differentiation factor 7 chr2 GO:0021953 Not Cancer Driver No 33 0.073 213 8 0.038 0
GIGYF2_ENST00000409547 GIGYF2 Q6Y7W6 GRB10-interacting GYF protein 2 chr2 GO:0021953 Not Cancer Driver No 176 0.135 1096 158 0.144 6
GRID2 GRID2 O43424 Glutamate receptor ionotropic, delta-2 chr4 GO:0021953 Not Cancer Driver No 350 0.348 155 35 0.226 3
GSX1 GSX1 Q9H4S2 GS homeobox 1 chr13 GO:0021953 Not Cancer Driver No 26 0.098 137 14 0.102 0
GSX2 GSX2 Q9BZM3 GS homeobox 2 chr4 GO:0021953 Not Cancer Driver No 44 0.145 210 26 0.124 1
HERC1 HERC1 Q15751 Probable E3 ubiquitin-protein ligase HERC1 chr15 GO:0021953 Not Cancer Driver No 487 0.1 1344 129 0.096 1
HPRT1 HPRT1 P00492 Hypoxanthine-guanine phosphoribosyltransferase chrX GO:0021953 Not Cancer Driver No 22 0.101 3 0 0.0 62
ID4 ID4 P47928 DNA-binding protein inhibitor ID-4 chr6 GO:0021953 Not Cancer Driver No 4 0.025 71 1 0.014 0
IFT172 IFT172 Q9UG01 Intraflagellar transport protein 172 homolog chr2 GO:0021953 Not Cancer Driver No 219 0.125 96 10 0.104 8
INHBA_ENST00000442711 INHBA P08476 Inhibin beta A chain chr7 GO:0021953 Not Cancer Driver No 148 0.347 154 63 0.409 0
ISL1 ISL1 P61371 Insulin gene enhancer protein ISL-1 chr5 GO:0021953 Not Cancer Driver No 85 0.244 180 41 0.228 0
ISL2 ISL2 Q96A47 Insulin gene enhancer protein ISL-2 chr15 GO:0021953 Not Cancer Driver No 42 0.117 167 16 0.096 0
KNDC1 KNDC1 Q76NI1 Kinase non-catalytic C-lobe domain-containing protein 1 chr10 GO:0021953 Not Cancer Driver No 276 0.158 805 124 0.154 0
LBX1 LBX1 P52954 Transcription factor LBX1 chr10 GO:0021953 Not Cancer Driver No 26 0.093 181 18 0.099 0
LDB1 LDB1 Q86U70 LIM domain-binding protein 1 chr10 GO:0021953 Compendium Yes 56 0.136 177 29 0.164 0
LHX3_ENST00000371748 LHX3 Q9UBR4 LIM/homeobox protein Lhx3 chr9 GO:0021953 Not Cancer Driver No 38 0.096 232 14 0.06 2
LHX5 LHX5 Q9H2C1 LIM/homeobox protein Lhx5 chr12 GO:0021953 Not Cancer Driver No 45 0.112 253 22 0.087 0
LMO4 LMO4 P61968 LIM domain transcription factor LMO4 chr1 GO:0021953 Not Cancer Driver No 30 0.182 11 1 0.091 0
LMX1A_ENST00000294816 LMX1A Q8TE12 LIM homeobox transcription factor 1-alpha chr1 GO:0021953 Not Cancer Driver No 117 0.306 186 65 0.349 1
MDGA1 MDGA1 Q8NFP4 MAM domain-containing glycosylphosphatidylinositol anchor protein 1 chr6 GO:0021953 Not Cancer Driver No 148 0.155 312 51 0.163 0
MDGA2 MDGA2 Q7Z553 MAM domain-containing glycosylphosphatidylinositol anchor protein 2 chr14 GO:0021953 Not Cancer Driver No 266 0.278 116 31 0.267 0
MTPN MTPN P58546 Myotrophin chr7 GO:0021953 Not Cancer Driver No 11 0.093 11 3 0.273 0
NKX2-2 NKX2-2 O95096 Homeobox protein Nkx-2.2 chr20 GO:0021953 Not Cancer Driver No 84 0.308 206 65 0.316 0
NKX6-1 NKX6-1 P78426 Homeobox protein Nkx-6.1 chr4 GO:0021953 Not Cancer Driver No 38 0.104 325 34 0.105 0
NR2E1_ENST00000368986 NR2E1 Q9Y466 Nuclear receptor subfamily 2 group E member 1 chr6 GO:0021953 Not Cancer Driver No 75 0.195 57 6 0.105 0
NR4A2_ENST00000409572 NR4A2 P43354 Nuclear receptor subfamily 4 group A member 2 chr2 GO:0021953 Not Cancer Driver No 110 0.184 261 38 0.146 0
OLIG2_ENST00000382357 OLIG2 Q13516 Oligodendrocyte transcription factor 2 chr21 GO:0021953 Census Yes 37 0.115 256 37 0.145 0
OPHN1 OPHN1 O60890 Oligophrenin-1 chrX GO:0021953 Not Cancer Driver No 122 0.152 302 42 0.139 0
OTP OTP Q5XKR4 Homeobox protein orthopedia chr5 GO:0021953 Not Cancer Driver No 36 0.111 278 29 0.104 0
PAFAH1B1 PAFAH1B1 P43034 Platelet-activating factor acetylhydrolase IB subunit beta chr17 GO:0021953 Not Cancer Driver No 42 0.102 82 11 0.134 7
PEX5_ENST00000420616 PEX5 P50542 Peroxisomal targeting signal 1 receptor chr12 GO:0021953 Not Cancer Driver No 73 0.114 321 36 0.112 2
PHOX2A PHOX2A O14813 Paired mesoderm homeobox protein 2A chr11 GO:0021953 Not Cancer Driver No 20 0.07 172 12 0.07 1
PHOX2B PHOX2B Q99453 Paired mesoderm homeobox protein 2B chr4 GO:0021953 Census Yes 59 0.188 219 44 0.201 2
POU4F1 POU4F1 Q01851 POU domain, class 4, transcription factor 1 chr13 GO:0021953 Not Cancer Driver No 51 0.122 273 34 0.125 1
PROX1 PROX1 Q92786 Prospero homeobox protein 1 chr1 GO:0021953 Not Cancer Driver No 182 0.247 537 141 0.263 0
PSEN1 PSEN1 P49768 Presenilin-1 chr14 GO:0021953 Not Cancer Driver No 61 0.131 134 21 0.157 96
PTCH1 PTCH1 Q13635 Protein patched homolog 1 chr9 GO:0021953 Census, Compendium Yes 243 0.168 382 67 0.175 18
RORA_ENST00000335670 RORA P35398 Nuclear receptor ROR-alpha chr15 GO:0021953 Not Cancer Driver No 57 0.109 182 17 0.093 4
SCYL1 SCYL1 Q96KG9 N-terminal kinase-like protein chr11 GO:0021953 Not Cancer Driver No 85 0.105 312 32 0.103 0
SCYL3_ENST00000367770 SCYL3 Q8IZE3 Protein-associating with the carboxyl-terminal domain of ezrin chr1 GO:0021953 Not Cancer Driver No 81 0.109 249 28 0.112 0
SHH SHH Q15465 Sonic hedgehog protein chr7 GO:0021953 Not Cancer Driver No 56 0.121 139 14 0.101 81
SIN3A_ENST00000360439 SIN3A Q96ST3 Paired amphipathic helix protein Sin3a chr15 GO:0021953 Compendium Yes 172 0.135 617 73 0.118 0
SLC25A46 SLC25A46 Q96AG3 Mitochondrial outer membrane protein SLC25A46 chr5 GO:0021953 Not Cancer Driver No 37 0.089 96 2 0.021 4
SMO SMO Q99835 Smoothened homolog chr7 GO:0021953 Census, Compendium Yes 112 0.142 241 27 0.112 1
SOX4 SOX4 Q06945 Transcription factor SOX-4 chr6 GO:0021953 Not Cancer Driver No 28 0.059 400 24 0.06 4
SPOCK1 SPOCK1 Q08629 Testican-1 chr5 GO:0021953 Not Cancer Driver No 82 0.187 107 16 0.15 0
TAL1 TAL1 P17542 T-cell acute lymphocytic leukemia protein 1 chr1 GO:0021953 Census Yes 54 0.163 305 53 0.174 0
TBX20 TBX20 Q9UMR3 T-box transcription factor TBX20 chr7 GO:0021953 Not Cancer Driver No 117 0.262 201 54 0.269 2
TCTN1_ENST00000551590 TCTN1 Q2MV58 Tectonic-1 chr12 GO:0021953 Not Cancer Driver No 63 0.107 47 6 0.128 0
TOX TOX O94900 Thymocyte selection-associated high mobility group box protein TOX chr8 GO:0021953 Not Cancer Driver No 112 0.213 494 108 0.219 0
TTC21B TTC21B Q7Z4L5 Tetratricopeptide repeat protein 21B chr2 GO:0021953 Not Cancer Driver No 176 0.134 73 14 0.192 11
TTLL1 TTLL1 O95922 Polyglutamylase complex subunit TTLL1 chr22 GO:0021953 Not Cancer Driver No 69 0.163 48 9 0.188 0
TULP3_ENST00000448120 TULP3 O75386 Tubby-related protein 3 chr12 GO:0021953 Not Cancer Driver No 66 0.149 218 29 0.133 0
WNT1 WNT1 P04628 Proto-oncogene Wnt-1 chr12 GO:0021953 Not Cancer Driver No 29 0.078 25 0 0.0 8
WNT3A WNT3A P56704 Protein Wnt-3a chr1 GO:0021953 Not Cancer Driver No 77 0.219 37 5 0.135 0
WNT7A WNT7A O00755 Protein Wnt-7a chr3 GO:0021953 Not Cancer Driver No 93 0.266 18 9 0.5 4
ZC4H2 ZC4H2 Q9NQZ6 Zinc finger C4H2 domain-containing protein chrX GO:0021953 Not Cancer Driver No 60 0.268 136 43 0.316 13
ZNF335 ZNF335 Q9H4Z2 Zinc finger protein 335 chr20 GO:0021953 Not Cancer Driver No 185 0.138 942 133 0.141 1
ZSWIM6 ZSWIM6 Q9HCJ5 Zinc finger SWIM domain-containing protein 6 chr5 GO:0021953 Not Cancer Driver No 64 0.053 244 7 0.029 1