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Total number of protein in "GO:0019955" GO term:  116

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
A2M A2M P01023 Alpha-2-macroglobulin chr12 GO:0019955 Not Cancer Driver No 260 0.176 144 22 0.153 0
ACKR3 ACKR3 P25106 Atypical chemokine receptor 3 chr2 GO:0019955 Census, Compendium Yes 78 0.215 0 0 0.0 1
ACVR1_ENST00000434821 ACVR1 Q04771 Activin receptor type-1 chr2 GO:0019955 Census, Compendium Yes 78 0.153 21 8 0.381 8
ACVRL1 ACVRL1 P37023 Serine/threonine-protein kinase receptor R3 chr12 GO:0019955 Not Cancer Driver No 93 0.185 60 11 0.183 82
BMPR1A BMPR1A P36894 Bone morphogenetic protein receptor type-1A chr10 GO:0019955 Census, Compendium Yes 66 0.124 21 0 0.0 8
BMPR1B_ENST00000394931 BMPR1B O00238 Bone morphogenetic protein receptor type-1B chr4 GO:0019955 Not Cancer Driver No 84 0.167 64 12 0.188 5
BMPR2 BMPR2 Q13873 Bone morphogenetic protein receptor type-2 chr2 GO:0019955 Compendium Yes 141 0.136 601 70 0.116 19
CCR1 CCR1 P32246 C-C chemokine receptor type 1 chr3 GO:0019955 Not Cancer Driver No 69 0.194 14 5 0.357 0
CCR2_ENST00000400888 CCR2 P41597 C-C chemokine receptor type 2 chr3 GO:0019955 Not Cancer Driver No 81 0.217 23 1 0.043 0
CCR5 CCR5 P51681 C-C chemokine receptor type 5 chr3 GO:0019955 Not Cancer Driver No 107 0.304 0 0 0.0 0
CCR7 CCR7 P32248 C-C chemokine receptor type 7 chr17 GO:0019955 Census, Compendium Yes 50 0.132 0 0 0.0 0
CD109 CD109 Q6YHK3 CD109 antigen chr6 GO:0019955 Not Cancer Driver No 204 0.141 54 11 0.204 0
CD36_ENST00000309881 CD36 P16671 Platelet glycoprotein 4 chr7 GO:0019955 Not Cancer Driver No 75 0.159 12 3 0.25 3
CD4 CD4 P01730 T-cell surface glycoprotein CD4 chr12 GO:0019955 Not Cancer Driver No 69 0.151 56 11 0.196 0
CD74 CD74 P04233 HLA class II histocompatibility antigen gamma chain chr5 GO:0019955 Census Yes 31 0.105 185 20 0.108 0
CER1 CER1 O95813 Cerberus chr9 GO:0019955 Not Cancer Driver No 70 0.262 119 27 0.227 0
CHRD CHRD Q9H2X0 Chordin chr3 GO:0019955 Not Cancer Driver No 171 0.179 308 61 0.198 0
CNTFR_ENST00000351266 CNTFR P26992 Ciliary neurotrophic factor receptor subunit alpha chr9 GO:0019955 Not Cancer Driver No 50 0.134 92 8 0.087 0
COMP COMP P49747 Cartilage oligomeric matrix protein chr19 GO:0019955 Not Cancer Driver No 97 0.128 306 52 0.17 61
COPS5 COPS5 Q92905 COP9 signalosome complex subunit 5 chr8 GO:0019955 Not Cancer Driver No 36 0.108 32 7 0.219 0
CRLF1 CRLF1 O75462 Cytokine receptor-like factor 1 chr19 GO:0019955 Not Cancer Driver No 51 0.121 101 7 0.069 14
CRLF2_ENST00000381566 CRLF2 Q9HC73 Cytokine receptor-like factor 2 chrX GO:0019955 Census Yes 54 0.146 62 3 0.048 0
CSF1R CSF1R P07333 Macrophage colony-stimulating factor 1 receptor chr5 GO:0019955 Census Yes 133 0.137 124 17 0.137 20
CSF2RA_ENST00000381524 CSF2RA P15509 Granulocyte-macrophage colony-stimulating factor receptor subunit alpha chrX GO:0019955 Not Cancer Driver No 148 0.37 12 2 0.167 1
CSF3R_ENST00000361632 CSF3R Q99062 Granulocyte colony-stimulating factor receptor chr1 GO:0019955 Census, Compendium Yes 131 0.157 209 34 0.163 2
CX3CR1_ENST00000542107 CX3CR1 P49238 CX3C chemokine receptor 1 chr3 GO:0019955 Not Cancer Driver No 80 0.225 0 0 0.0 0
CXCR1 CXCR1 P25024 C-X-C chemokine receptor type 1 chr2 GO:0019955 Not Cancer Driver No 71 0.203 0 0 0.0 0
CXCR2 CXCR2 P25025 C-X-C chemokine receptor type 2 chr2 GO:0019955 Not Cancer Driver No 87 0.242 8 0 0.0 0
EBI3 EBI3 Q14213 Interleukin-27 subunit beta chr19 GO:0019955 Not Cancer Driver No 32 0.14 10 1 0.1 0
ELANE_ENST00000263621 ELANE P08246 Neutrophil elastase chr19 GO:0019955 Not Cancer Driver No 39 0.146 18 3 0.167 89
ENG ENG P17813 Endoglin chr9 GO:0019955 Not Cancer Driver No 60 0.091 114 15 0.132 32
FZD4 FZD4 Q9ULV1 Frizzled-4 chr11 GO:0019955 Not Cancer Driver No 57 0.106 33 5 0.152 19
GBP1 GBP1 P32455 Guanylate-binding protein 1 chr1 GO:0019955 Not Cancer Driver No 92 0.155 166 27 0.163 0
GDF5_ENST00000374369 GDF5 P43026 Growth/differentiation factor 5 chr20 GO:0019955 Not Cancer Driver No 104 0.208 255 50 0.196 24
GHR_ENST00000612382 GHR P10912 Growth hormone receptor chr5 GO:0019955 Not Cancer Driver No 173 0.271 229 66 0.288 19
GREM1 GREM1 O60565 Gremlin-1 chr15 GO:0019955 Not Cancer Driver No 25 0.136 77 12 0.156 0
GREM2 GREM2 Q9H772 Gremlin-2 chr1 GO:0019955 Not Cancer Driver No 54 0.321 22 9 0.409 3
HAX1 HAX1 O00165 HCLS1-associated protein X-1 chr1 GO:0019955 Not Cancer Driver No 44 0.158 219 32 0.146 2
HJV HJV Q6ZVN8 Hemojuvelin chr1 GO:0019955 Not Cancer Driver No 75 0.176 117 27 0.231 14
HMGB1_ENST00000405805 HMGB1 P09429 High mobility group protein B1 chr13 GO:0019955 Not Cancer Driver No 25 0.116 203 20 0.099 0
HYAL2_ENST00000357750 HYAL2 Q12891 Hyaluronidase-2 chr3 GO:0019955 Not Cancer Driver No 52 0.11 8 1 0.125 0
IFNAR1 IFNAR1 P17181 Interferon alpha/beta receptor 1 chr21 GO:0019955 Compendium Yes 55 0.099 50 6 0.12 0
IFNGR1 IFNGR1 P15260 Interferon gamma receptor 1 chr6 GO:0019955 Compendium Yes 55 0.112 175 22 0.126 10
IL10RA IL10RA Q13651 Interleukin-10 receptor subunit alpha chr11 GO:0019955 Not Cancer Driver No 77 0.133 220 26 0.118 7
IL11RA_ENST00000441545 IL11RA Q14626 Interleukin-11 receptor subunit alpha chr9 GO:0019955 Not Cancer Driver No 48 0.114 153 11 0.072 3
IL12B IL12B P29460 Interleukin-12 subunit beta chr5 GO:0019955 Not Cancer Driver No 48 0.146 42 2 0.048 0
IL12RB1_ENST00000593993 IL12RB1 P42701 Interleukin-12 receptor subunit beta-1 chr19 GO:0019955 Not Cancer Driver No 108 0.163 207 38 0.184 1
IL12RB2 IL12RB2 Q99665 Interleukin-12 receptor subunit beta-2 chr1 GO:0019955 Not Cancer Driver No 129 0.15 195 31 0.159 0
IL13RA1 IL13RA1 P78552 Interleukin-13 receptor subunit alpha-1 chrX GO:0019955 Not Cancer Driver No 58 0.136 33 7 0.212 0
IL13RA2_ENST00000243213 IL13RA2 Q14627 Interleukin-13 receptor subunit alpha-2 chrX GO:0019955 Not Cancer Driver No 69 0.182 0 0 0.0 0
IL17F IL17F Q96PD4 Interleukin-17F chr6 GO:0019955 Not Cancer Driver No 42 0.258 34 11 0.324 1
IL18BP_ENST00000337131 IL18BP O95998 Interleukin-18-binding protein chr11 GO:0019955 Not Cancer Driver No 16 0.082 50 6 0.12 0
IL18R1_ENST00000233957 IL18R1 Q13478 Interleukin-18 receptor 1 chr2 GO:0019955 Not Cancer Driver No 104 0.192 18 3 0.167 0
IL1R1 IL1R1 P14778 Interleukin-1 receptor type 1 chr2 GO:0019955 Not Cancer Driver No 77 0.135 59 8 0.136 0
IL1R2_ENST00000393414 IL1R2 P27930 Interleukin-1 receptor type 2 chr2 GO:0019955 Not Cancer Driver No 75 0.188 32 10 0.312 0
IL1RAPL1 IL1RAPL1 Q9NZN1 Interleukin-1 receptor accessory protein-like 1 chrX GO:0019955 Not Cancer Driver No 205 0.295 77 19 0.247 0
IL1RL1 IL1RL1 Q01638 Interleukin-1 receptor-like 1 chr2 GO:0019955 Not Cancer Driver No 119 0.214 24 8 0.333 0
IL1RN_ENST00000409930 IL1RN P18510 Interleukin-1 receptor antagonist protein chr2 GO:0019955 Not Cancer Driver No 34 0.192 17 7 0.412 0
IL20RA IL20RA Q9UHF4 Interleukin-20 receptor subunit alpha chr6 GO:0019955 Not Cancer Driver No 72 0.13 231 29 0.126 0
IL20RB IL20RB Q6UXL0 Interleukin-20 receptor subunit beta chr3 GO:0019955 Not Cancer Driver No 40 0.129 0 0 0.0 0
IL22RA1 IL22RA1 Q8N6P7 Interleukin-22 receptor subunit alpha-1 chr1 GO:0019955 Not Cancer Driver No 66 0.115 297 37 0.125 0
IL22RA2 IL22RA2 Q969J5 Interleukin-22 receptor subunit alpha-2 chr6 GO:0019955 Not Cancer Driver No 35 0.133 14 3 0.214 0
IL23R IL23R Q5VWK5 Interleukin-23 receptor chr1 GO:0019955 Not Cancer Driver No 70 0.111 117 19 0.162 0
IL27RA IL27RA Q6UWB1 Interleukin-27 receptor subunit alpha chr19 GO:0019955 Not Cancer Driver No 91 0.143 167 23 0.138 0
IL2RA IL2RA P01589 Interleukin-2 receptor subunit alpha chr10 GO:0019955 Not Cancer Driver No 51 0.188 131 29 0.221 2
IL2RB IL2RB P14784 Interleukin-2 receptor subunit beta chr22 GO:0019955 Not Cancer Driver No 81 0.147 182 33 0.181 1
IL2RG IL2RG P31785 Cytokine receptor common subunit gamma chrX GO:0019955 Not Cancer Driver No 56 0.152 32 6 0.188 33
IL31RA_ENST00000297015 IL31RA Q8NI17 Interleukin-31 receptor subunit alpha chr5 GO:0019955 Not Cancer Driver No 117 0.16 163 30 0.184 1
IL36RN_ENST00000346807 IL36RN Q9UBH0 Interleukin-36 receptor antagonist protein chr2 GO:0019955 Not Cancer Driver No 34 0.219 7 4 0.571 4
IL3RA IL3RA P26951 Interleukin-3 receptor subunit alpha chrX GO:0019955 Not Cancer Driver No 89 0.235 9 2 0.222 0
IL5RA_ENST00000256452 IL5RA Q01344 Interleukin-5 receptor subunit alpha chr3 GO:0019955 Not Cancer Driver No 92 0.219 23 5 0.217 0
IL6R IL6R P08887 Interleukin-6 receptor subunit alpha chr1 GO:0019955 Not Cancer Driver No 55 0.118 165 23 0.139 1
IL6ST_ENST00000336909 IL6ST P40189 Interleukin-6 receptor subunit beta chr5 GO:0019955 Census, Compendium Yes 102 0.111 315 40 0.127 2
IL9R IL9R Q01113 Interleukin-9 receptor chrX GO:0019955 Not Cancer Driver No 96 0.184 78 18 0.231 0
ITGA4 ITGA4 P13612 Integrin alpha-4 chr2 GO:0019955 Not Cancer Driver No 254 0.246 97 27 0.278 0
ITGAV ITGAV P06756 Integrin alpha-V chr2 GO:0019955 Census Yes 153 0.146 92 9 0.098 0
ITGB1_ENST00000302278 ITGB1 P05556 Integrin beta-1 chr10 GO:0019955 Not Cancer Driver No 103 0.129 84 10 0.119 0
ITGB3 ITGB3 P05106 Integrin beta-3 chr17 GO:0019955 Not Cancer Driver No 124 0.157 66 5 0.076 30
KIT KIT P10721 Mast/stem cell growth factor receptor Kit chr4 GO:0019955 Census, Compendium Yes 226 0.232 83 33 0.398 21
KLHL20 KLHL20 Q9Y2M5 Kelch-like protein 20 chr1 GO:0019955 Not Cancer Driver No 83 0.136 143 17 0.119 0
LEPR LEPR P48357 Leptin receptor chr1 GO:0019955 Not Cancer Driver No 243 0.209 57 11 0.193 0
LIFR_ENST00000453190 LIFR P42702 Leukemia inhibitory factor receptor chr5 GO:0019955 Census, Compendium Yes 247 0.225 259 56 0.216 1
LRRC32_ENST00000404995 LRRC32 Q14392 Transforming growth factor beta activator LRRC32 chr11 GO:0019955 Not Cancer Driver No 130 0.196 28 4 0.143 0
LTBP1 LTBP1 Q14766 Latent-transforming growth factor beta-binding protein 1 chr2 GO:0019955 Not Cancer Driver No 300 0.174 518 78 0.151 0
LTBP3 LTBP3 Q9NS15 Latent-transforming growth factor beta-binding protein 3 chr11 GO:0019955 Not Cancer Driver No 108 0.083 356 22 0.062 0
LTBP4 LTBP4 Q8N2S1 Latent-transforming growth factor beta-binding protein 4 chr19 GO:0019955 Not Cancer Driver No 191 0.118 432 42 0.097 1
NBL1_ENST00000602662 NBL1 P41271 Neuroblastoma suppressor of tumorigenicity 1 chr1 GO:0019955 Not Cancer Driver No 18 0.099 64 4 0.062 0
NLRP7_ENST00000590030 NLRP7 Q8WX94 NACHT, LRR and PYD domains-containing protein 7 chr19 GO:0019955 Not Cancer Driver No 300 0.306 71 20 0.282 9
NOG NOG Q13253 Noggin chr17 GO:0019955 Not Cancer Driver No 22 0.095 86 9 0.105 20
NRP1 NRP1 O14786 Neuropilin-1 chr10 GO:0019955 Compendium Yes 146 0.158 211 31 0.147 0
NRP2 NRP2 O60462 Neuropilin-2 chr2 GO:0019955 Not Cancer Driver No 161 0.173 207 45 0.217 0
NRROS NRROS Q86YC3 Transforming growth factor beta activator LRRC33 chr3 GO:0019955 Not Cancer Driver No 109 0.158 8 1 0.125 0
OSMR OSMR Q99650 Oncostatin-M-specific receptor subunit beta chr5 GO:0019955 Not Cancer Driver No 167 0.171 145 22 0.152 5
PARK7_ENST00000377488 PARK7 Q99497 Parkinson disease protein 7 chr1 GO:0019955 Not Cancer Driver No 11 0.058 30 0 0.0 5
PRLR PRLR P16471 Prolactin receptor chr5 GO:0019955 Not Cancer Driver No 154 0.248 282 70 0.248 2
PXDN PXDN Q92626 Peroxidasin homolog chr2 GO:0019955 Not Cancer Driver No 332 0.224 307 77 0.251 1
SCUBE3 SCUBE3 Q8IX30 Signal peptide, CUB and EGF-like domain-containing protein 3 chr6 GO:0019955 Not Cancer Driver No 131 0.132 110 17 0.155 2
SOST SOST Q9BQB4 Sclerostin chr17 GO:0019955 Not Cancer Driver No 30 0.141 90 12 0.133 3
SOSTDC1 SOSTDC1 Q6X4U4 Sclerostin domain-containing protein 1 chr7 GO:0019955 Not Cancer Driver No 22 0.107 72 3 0.042 0
SPINT3 SPINT3 P49223 Kunitz-type protease inhibitor 3 chr20 GO:0019955 Not Cancer Driver No 7 0.079 0 0 0.0 0
TCAP TCAP O15273 Telethonin chr17 GO:0019955 Not Cancer Driver No 16 0.096 94 10 0.106 3
TGFB3 TGFB3 P10600 Transforming growth factor beta-3 proprotein chr14 GO:0019955 Not Cancer Driver No 45 0.109 96 14 0.146 1
TGFBR1_ENST00000374994 TGFBR1 P36897 TGF-beta receptor type-1 chr9 GO:0019955 Not Cancer Driver No 86 0.171 23 3 0.13 15
TGFBR2_ENST00000295754 TGFBR2 P37173 TGF-beta receptor type-2 chr3 GO:0019955 Census, Compendium Yes 106 0.187 60 16 0.267 25
TGFBR3_ENST00000525962 TGFBR3 Q03167 Transforming growth factor beta receptor type 3 chr1 GO:0019955 Not Cancer Driver No 129 0.152 268 41 0.153 0
THBS1 THBS1 P07996 Thrombospondin-1 chr15 GO:0019955 Not Cancer Driver No 188 0.161 320 58 0.181 0
TNFRSF11A TNFRSF11A Q9Y6Q6 Tumor necrosis factor receptor superfamily member 11A chr18 GO:0019955 Not Cancer Driver No 70 0.114 285 33 0.116 0
TNFRSF14 TNFRSF14 Q92956 Tumor necrosis factor receptor superfamily member 14 chr1 GO:0019955 Census, Compendium Yes 33 0.117 54 8 0.148 0
TNFRSF9 TNFRSF9 Q07011 Tumor necrosis factor receptor superfamily member 9 chr1 GO:0019955 Not Cancer Driver No 43 0.169 29 10 0.345 0
TRIM16_ENST00000336708 TRIM16 O95361 Tripartite motif-containing protein 16 chr17 GO:0019955 Not Cancer Driver No 64 0.113 132 11 0.083 0
TSKU_ENST00000333090 TSKU Q8WUA8 Tsukushi chr11 GO:0019955 Not Cancer Driver No 53 0.15 44 6 0.136 0
TWSG1 TWSG1 Q9GZX9 Twisted gastrulation protein homolog 1 chr18 GO:0019955 Not Cancer Driver No 27 0.121 19 3 0.158 0
UCMA UCMA Q8WVF2 Unique cartilage matrix-associated protein chr10 GO:0019955 Not Cancer Driver No 33 0.239 96 22 0.229 0
VASN VASN Q6EMK4 Vasorin chr16 GO:0019955 Not Cancer Driver No 37 0.055 233 8 0.034 0
WFIKKN1 WFIKKN1 Q96NZ8 WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 1 chr16 GO:0019955 Not Cancer Driver No 38 0.069 90 4 0.044 0
WFIKKN2 WFIKKN2 Q8TEU8 WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 chr17 GO:0019955 Not Cancer Driver No 114 0.198 94 32 0.34 0