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Total number of protein in "GO:0019900" GO term:  242

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABI2_ENST00000261018 ABI2 Q9NYB9 Abl interactor 2 chr2 GO:0019900 Not Cancer Driver No 56 0.109 361 38 0.105 0
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0019900 Census, Compendium Yes 139 0.123 604 73 0.121 2
ACE ACE P12821 Angiotensin-converting enzyme chr17 GO:0019900 Not Cancer Driver No 201 0.154 86 8 0.093 0
ADAM9 ADAM9 Q13443 Disintegrin and metalloproteinase domain-containing protein 9 chr8 GO:0019900 Not Cancer Driver No 86 0.105 129 13 0.101 0
ADCY4_ENST00000554068 ADCY4 Q8NFM4 Adenylate cyclase type 4 chr14 GO:0019900 Not Cancer Driver No 137 0.127 94 23 0.245 0
ADCY6 ADCY6 O43306 Adenylate cyclase type 6 chr12 GO:0019900 Not Cancer Driver No 144 0.123 147 17 0.116 1
ANKRD2 ANKRD2 Q9GZV1 Ankyrin repeat domain-containing protein 2 chr10 GO:0019900 Not Cancer Driver No 34 0.094 192 18 0.094 0
APPL1 APPL1 Q9UKG1 DCC-interacting protein 13-alpha chr3 GO:0019900 Not Cancer Driver No 67 0.094 292 31 0.106 1
ARRB2_ENST00000269260 ARRB2 P32121 Beta-arrestin-2 chr17 GO:0019900 Not Cancer Driver No 46 0.112 122 22 0.18 0
ATF5_ENST00000595125 ATF5 Q9Y2D1 Cyclic AMP-dependent transcription factor ATF-5 chr19 GO:0019900 Not Cancer Driver No 47 0.167 239 40 0.167 0
ATF7_ENST00000456903 ATF7 P17544 Cyclic AMP-dependent transcription factor ATF-7 chr12 GO:0019900 Not Cancer Driver No 45 0.093 468 45 0.096 0
ATP1A4 ATP1A4 Q13733 Sodium/potassium-transporting ATPase subunit alpha-4 chr1 GO:0019900 Not Cancer Driver No 195 0.19 117 24 0.205 0
AURKB_ENST00000585124 AURKB Q96GD4 Aurora kinase B chr17 GO:0019900 Not Cancer Driver No 51 0.148 63 8 0.127 0
AVPR1A AVPR1A P37288 Vasopressin V1a receptor chr12 GO:0019900 Not Cancer Driver No 105 0.251 68 25 0.368 0
AVPR1B AVPR1B P47901 Vasopressin V1b receptor chr1 GO:0019900 Not Cancer Driver No 83 0.196 51 5 0.098 0
BAD_ENST00000309032 BAD Q92934 Bcl2-associated agonist of cell death chr11 GO:0019900 Not Cancer Driver No 14 0.083 163 14 0.086 0
BARD1 BARD1 Q99728 BRCA1-associated RING domain protein 1 chr2 GO:0019900 Census Yes 96 0.124 384 49 0.128 0
BCAR3_ENST00000260502 BCAR3 O75815 Breast cancer anti-estrogen resistance protein 3 chr1 GO:0019900 Not Cancer Driver No 102 0.124 395 42 0.106 0
BCL10 BCL10 O95999 B-cell lymphoma/leukemia 10 chr1 GO:0019900 Census, Compendium Yes 36 0.155 151 25 0.166 0
BLNK BLNK Q8WV28 B-cell linker protein chr10 GO:0019900 Not Cancer Driver No 74 0.162 376 61 0.162 0
BTG1 BTG1 P62324 Protein BTG1 chr12 GO:0019900 Census, Compendium Yes 21 0.123 19 0 0.0 0
C1QBP C1QBP Q07021 Complement component 1 Q subcomponent-binding protein, mitochondrial chr17 GO:0019900 Not Cancer Driver No 14 0.05 103 6 0.058 2
CAB39 CAB39 Q9Y376 Calcium-binding protein 39 chr2 GO:0019900 Not Cancer Driver No 31 0.091 43 5 0.116 0
CARD16 CARD16 Q5EG05 Caspase recruitment domain-containing protein 16 chr11 GO:0019900 Not Cancer Driver No 36 0.183 23 7 0.304 0
CASP1 CASP1 P29466 Caspase-1 chr11 GO:0019900 Not Cancer Driver No 79 0.196 87 18 0.207 0
CAVIN2 CAVIN2 O95810 Caveolae-associated protein 2 chr2 GO:0019900 Not Cancer Driver No 109 0.256 393 99 0.252 0
CAVIN3 CAVIN3 Q969G5 Caveolae-associated protein 3 chr11 GO:0019900 Not Cancer Driver No 22 0.084 234 19 0.081 0
CCDC88A_ENST00000642200 CCDC88A Q3V6T2 Girdin chr2 GO:0019900 Not Cancer Driver No 226 0.121 1481 173 0.117 0
CD160_ENST00000369288 CD160 O95971 CD160 antigen chr1 GO:0019900 Not Cancer Driver No 20 0.11 2 0 0.0 0
CDC37 CDC37 Q16543 Hsp90 co-chaperone Cdc37 chr19 GO:0019900 Not Cancer Driver No 52 0.138 214 31 0.145 0
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 GO:0019900 Not Cancer Driver No 39 0.204 23 2 0.087 1
CDC6 CDC6 Q99741 Cell division control protein 6 homolog chr17 GO:0019900 Not Cancer Driver No 57 0.102 170 15 0.088 1
CDK5RAP3_ENST00000338399 CDK5RAP3 Q96JB5 CDK5 regulatory subunit-associated protein 3 chr17 GO:0019900 Not Cancer Driver No 50 0.099 99 20 0.202 0
CEACAM1 CEACAM1 P13688 Carcinoembryonic antigen-related cell adhesion molecule 1 chr19 GO:0019900 Not Cancer Driver No 64 0.122 241 25 0.104 0
CEBPA CEBPA P49715 CCAAT/enhancer-binding protein alpha chr19 GO:0019900 Census, Compendium Yes 12 0.034 342 12 0.035 1
CEBPB CEBPB P17676 CCAAT/enhancer-binding protein beta chr20 GO:0019900 Not Cancer Driver No 3 0.009 276 2 0.007 0
CHIA_ENST00000343320 CHIA Q9BZP6 Acidic mammalian chitinase chr1 GO:0019900 Not Cancer Driver No 116 0.244 42 10 0.238 0
CHP1 CHP1 Q99653 Calcineurin B homologous protein 1 chr15 GO:0019900 Not Cancer Driver No 27 0.138 70 12 0.171 0
CNOT9_ENST00000273064 CNOT9 Q92600 CCR4-NOT transcription complex subunit 9 chr2 GO:0019900 Compendium Yes 42 0.14 30 0 0.0 0
CRK CRK P46108 Adapter molecule crk chr17 GO:0019900 Not Cancer Driver No 30 0.099 197 23 0.117 0
CSK_ENST00000439220 CSK P41240 Tyrosine-protein kinase CSK chr15 GO:0019900 Not Cancer Driver No 41 0.091 18 1 0.056 0
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 GO:0019900 Census, Compendium Yes 415 0.531 288 301 1.045 14
DAB2IP_ENST00000408936 DAB2IP Q5VWQ8 Disabled homolog 2-interacting protein chr9 GO:0019900 Not Cancer Driver No 131 0.11 681 68 0.1 0
DACT1 DACT1 Q9NYF0 Dapper homolog 1 chr14 GO:0019900 Not Cancer Driver No 163 0.195 598 127 0.212 1
DACT2 DACT2 Q5SW24 Dapper homolog 2 chr6 GO:0019900 Not Cancer Driver No 35 0.045 655 30 0.046 0
DACT3 DACT3 Q96B18 Dapper homolog 3 chr19 GO:0019900 Not Cancer Driver No 17 0.027 549 12 0.022 0
DAZAP2_ENST00000412716 DAZAP2 Q15038 DAZ-associated protein 2 chr12 GO:0019900 Not Cancer Driver No 17 0.101 68 7 0.103 0
DGKD DGKD Q16760 Diacylglycerol kinase delta chr2 GO:0019900 Not Cancer Driver No 160 0.132 441 60 0.136 0
DGKQ DGKQ P52824 Diacylglycerol kinase theta chr4 GO:0019900 Not Cancer Driver No 56 0.059 264 11 0.042 0
DIRAS1_ENST00000585334 DIRAS1 O95057 GTP-binding protein Di-Ras1 chr19 GO:0019900 Not Cancer Driver No 38 0.192 32 5 0.156 0
DIXDC1 DIXDC1 Q155Q3 Dixin chr11 GO:0019900 Not Cancer Driver No 72 0.105 495 55 0.111 0
DLG1_ENST00000419354 DLG1 Q12959 Disks large homolog 1 chr3 GO:0019900 Not Cancer Driver No 120 0.133 460 67 0.146 0
DLG2_ENST00000398309 DLG2 Q15700 Disks large homolog 2 chr11 GO:0019900 Not Cancer Driver No 224 0.257 303 107 0.353 0
DLG3 DLG3 Q92796 Disks large homolog 3 chrX GO:0019900 Not Cancer Driver No 94 0.115 322 30 0.093 0
DLG4_ENST00000399506 DLG4 P78352 Disks large homolog 4 chr17 GO:0019900 Not Cancer Driver No 116 0.16 232 55 0.237 0
DOK2 DOK2 O60496 Docking protein 2 chr8 GO:0019900 Not Cancer Driver No 58 0.141 254 31 0.122 0
DSP DSP P15924 Desmoplakin chr6 GO:0019900 Not Cancer Driver No 483 0.168 1124 204 0.181 6
DUSP1 DUSP1 P28562 Dual specificity protein phosphatase 1 chr5 GO:0019900 Not Cancer Driver No 31 0.084 7 0 0.0 0
DUSP10 DUSP10 Q9Y6W6 Dual specificity protein phosphatase 10 chr1 GO:0019900 Not Cancer Driver No 81 0.168 135 24 0.178 0
DUSP12 DUSP12 Q9UNI6 Dual specificity protein phosphatase 12 chr1 GO:0019900 Not Cancer Driver No 33 0.097 30 1 0.033 0
DUSP16 DUSP16 Q9BY84 Dual specificity protein phosphatase 16 chr12 GO:0019900 Compendium Yes 70 0.105 273 34 0.125 0
DUSP19 DUSP19 Q8WTR2 Dual specificity protein phosphatase 19 chr2 GO:0019900 Not Cancer Driver No 34 0.157 15 5 0.333 0
DUSP2 DUSP2 Q05923 Dual specificity protein phosphatase 2 chr2 GO:0019900 Not Cancer Driver No 24 0.076 23 3 0.13 0
EEF1A1 EEF1A1 P68104 Elongation factor 1-alpha 1 chr6 GO:0019900 Not Cancer Driver No 109 0.236 100 14 0.14 0
EGFR EGFR P00533 Epidermal growth factor receptor chr7 GO:0019900 Census, Compendium Yes 444 0.367 223 35 0.157 1
EIF4ENIF1 EIF4ENIF1 Q9NRA8 Eukaryotic translation initiation factor 4E transporter chr22 GO:0019900 Not Cancer Driver No 116 0.118 899 101 0.112 0
EMP2_ENST00000536829 EMP2 P54851 Epithelial membrane protein 2 chr16 GO:0019900 Not Cancer Driver No 24 0.144 0 0 0.0 2
EZR EZR P15311 Ezrin chr6 GO:0019900 Census Yes 66 0.113 295 35 0.119 0
FAM83B FAM83B Q5T0W9 Protein FAM83B chr6 GO:0019900 Not Cancer Driver No 314 0.311 684 219 0.32 0
FAS FAS P25445 Tumor necrosis factor receptor superfamily member 6 chr10 GO:0019900 Census, Compendium Yes 55 0.164 62 18 0.29 22
FCRL3_ENST00000368184 FCRL3 Q96P31 Fc receptor-like protein 3 chr1 GO:0019900 Not Cancer Driver No 193 0.263 217 44 0.203 0
FEZ1 FEZ1 Q99689 Fasciculation and elongation protein zeta-1 chr11 GO:0019900 Not Cancer Driver No 66 0.168 277 49 0.177 0
FLNA FLNA P21333 Filamin-A chrX GO:0019900 Census Yes 416 0.157 1456 214 0.147 28
FRS2 FRS2 Q8WU20 Fibroblast growth factor receptor substrate 2 chr12 GO:0019900 Not Cancer Driver No 69 0.136 415 58 0.14 0
FRS3_ENST00000259748 FRS3 O43559 Fibroblast growth factor receptor substrate 3 chr6 GO:0019900 Not Cancer Driver No 77 0.157 388 58 0.149 0
GAB2 GAB2 Q9UQC2 GRB2-associated-binding protein 2 chr11 GO:0019900 Not Cancer Driver No 85 0.126 537 73 0.136 0
GADD45A GADD45A P24522 Growth arrest and DNA damage-inducible protein GADD45 alpha chr1 GO:0019900 Not Cancer Driver No 10 0.061 39 5 0.128 0
GCH1_ENST00000622544 GCH1 P30793 GTP cyclohydrolase 1 chr14 GO:0019900 Not Cancer Driver No 20 0.08 99 5 0.051 38
GFAP_ENST00000588735 GFAP P14136 Glial fibrillary acidic protein chr17 GO:0019900 Not Cancer Driver No 65 0.15 288 42 0.146 62
GLRX3 GLRX3 O76003 Glutaredoxin-3 chr10 GO:0019900 Not Cancer Driver No 52 0.155 24 4 0.167 0
GRK5 GRK5 P34947 G protein-coupled receptor kinase 5 chr10 GO:0019900 Not Cancer Driver No 77 0.131 103 18 0.175 0
GSK3A GSK3A P49840 Glycogen synthase kinase-3 alpha chr19 GO:0019900 Not Cancer Driver No 55 0.114 180 8 0.044 0
GSK3B_ENST00000264235 GSK3B P49841 Glycogen synthase kinase-3 beta chr3 GO:0019900 Not Cancer Driver No 56 0.133 146 13 0.089 0
GSN GSN P06396 Gelsolin chr9 GO:0019900 Not Cancer Driver No 76 0.097 316 28 0.089 2
GSTP1_ENST00000642444 GSTP1 P09211 Glutathione S-transferase P chr11 GO:0019900 Not Cancer Driver No 32 0.152 0 0 0.0 0
HDAC5_ENST00000586802 HDAC5 Q9UQL6 Histone deacetylase 5 chr17 GO:0019900 Not Cancer Driver No 118 0.105 718 73 0.102 0
HDAC7_ENST00000427332 HDAC7 Q8WUI4 Histone deacetylase 7 chr12 GO:0019900 Not Cancer Driver No 91 0.096 570 50 0.088 0
HDAC9_ENST00000432645 HDAC9 Q9UKV0 Histone deacetylase 9 chr7 GO:0019900 Not Cancer Driver No 286 0.283 631 178 0.282 0
HES1 HES1 Q14469 Transcription factor HES-1 chr3 GO:0019900 Not Cancer Driver No 37 0.132 226 32 0.142 0
HINT1 HINT1 P49773 Adenosine 5'-monophosphoramidase HINT1 chr5 GO:0019900 Not Cancer Driver No 11 0.087 6 0 0.0 6
HPCA HPCA P84074 Neuron-specific calcium-binding protein hippocalcin chr1 GO:0019900 Not Cancer Driver No 24 0.124 42 4 0.095 3
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 GO:0019900 Census, Compendium Yes 100 0.138 254 43 0.169 0
HSPB1 HSPB1 P04792 Heat shock protein beta-1 chr7 GO:0019900 Not Cancer Driver No 10 0.049 118 8 0.068 20
HTT HTT P42858 Huntingtin chr4 GO:0019900 Not Cancer Driver No 336 0.107 666 69 0.104 2
IRS1 IRS1 P35568 Insulin receptor substrate 1 chr2 GO:0019900 Not Cancer Driver No 161 0.13 1072 133 0.124 2
ITGAV ITGAV P06756 Integrin alpha-V chr2 GO:0019900 Census Yes 153 0.146 92 9 0.098 0
JAKMIP1_ENST00000282924 JAKMIP1 Q96N16 Janus kinase and microtubule-interacting protein 1 chr4 GO:0019900 Not Cancer Driver No 163 0.26 388 118 0.304 0
JAKMIP2_ENST00000265272 JAKMIP2 Q96AA8 Janus kinase and microtubule-interacting protein 2 chr5 GO:0019900 Not Cancer Driver No 169 0.209 475 101 0.213 0
JAKMIP3 JAKMIP3 Q5VZ66 Janus kinase and microtubule-interacting protein 3 chr10 GO:0019900 Not Cancer Driver No 111 0.132 358 49 0.137 0
KCNQ1 KCNQ1 P51787 Potassium voltage-gated channel subfamily KQT member 1 chr11 GO:0019900 Not Cancer Driver No 78 0.115 219 20 0.091 132
KIAA1614 KIAA1614 Q5VZ46 Uncharacterized protein KIAA1614 chr1 GO:0019900 Not Cancer Driver No 160 0.134 1160 159 0.137 0
LAPTM4B_ENST00000619747 LAPTM4B Q86VI4 Lysosomal-associated transmembrane protein 4B chr8 GO:0019900 Not Cancer Driver No 24 0.076 73 5 0.068 0
LDB3_ENST00000361373 LDB3 O75112 LIM domain-binding protein 3 chr10 GO:0019900 Not Cancer Driver No 107 0.147 529 71 0.134 4
LRRC14 LRRC14 Q15048 Leucine-rich repeat-containing protein 14 chr8 GO:0019900 Not Cancer Driver No 63 0.128 25 2 0.08 0
MAD2L2 MAD2L2 Q9UI95 Mitotic spindle assembly checkpoint protein MAD2B chr1 GO:0019900 Not Cancer Driver No 22 0.104 0 0 0.0 1
MAP2K7_ENST00000397979 MAP2K7 O14733 Dual specificity mitogen-activated protein kinase kinase 7 chr19 GO:0019900 Compendium Yes 89 0.212 144 20 0.139 0
MAP3K11 MAP3K11 Q16584 Mitogen-activated protein kinase kinase kinase 11 chr11 GO:0019900 Not Cancer Driver No 97 0.115 466 54 0.116 0
MAP4K2 MAP4K2 Q12851 Mitogen-activated protein kinase kinase kinase kinase 2 chr11 GO:0019900 Not Cancer Driver No 78 0.095 243 23 0.095 0
MAPK14_ENST00000229794 MAPK14 Q16539 Mitogen-activated protein kinase 14 chr6 GO:0019900 Not Cancer Driver No 39 0.108 25 1 0.04 0
MAPK7 MAPK7 Q13164 Mitogen-activated protein kinase 7 chr17 GO:0019900 Not Cancer Driver No 92 0.113 490 50 0.102 0
MAPK8IP3_ENST00000250894 MAPK8IP3 Q9UPT6 C-Jun-amino-terminal kinase-interacting protein 3 chr16 GO:0019900 Not Cancer Driver No 179 0.134 746 110 0.147 3
MAPK8_ENST00000374189 MAPK8 P45983 Mitogen-activated protein kinase 8 chr10 GO:0019900 Not Cancer Driver No 64 0.15 94 9 0.096 0
MAPKAPK2 MAPKAPK2 P49137 MAP kinase-activated protein kinase 2 chr1 GO:0019900 Not Cancer Driver No 43 0.107 92 5 0.054 0
MAPKAPK3 MAPKAPK3 Q16644 MAP kinase-activated protein kinase 3 chr3 GO:0019900 Not Cancer Driver No 35 0.092 117 12 0.103 1
MAPKAPK5 MAPKAPK5 Q8IW41 MAP kinase-activated protein kinase 5 chr12 GO:0019900 Not Cancer Driver No 51 0.108 101 12 0.119 0
MARCKS MARCKS P29966 Myristoylated alanine-rich C-kinase substrate chr6 GO:0019900 Not Cancer Driver No 14 0.042 328 14 0.043 0
MARVELD3_ENST00000268485 MARVELD3 Q96A59 MARVEL domain-containing protein 3 chr16 GO:0019900 Not Cancer Driver No 40 0.1 179 10 0.056 0
MIDN MIDN Q504T8 Midnolin chr19 GO:0019900 Not Cancer Driver No 43 0.092 446 43 0.096 0
MOB1B_ENST00000309395 MOB1B Q7L9L4 MOB kinase activator 1B chr4 GO:0019900 Not Cancer Driver No 17 0.079 7 0 0.0 0
MYCN MYCN P04198 N-myc proto-oncogene protein chr2 GO:0019900 Census, Compendium Yes 71 0.153 415 64 0.154 3
MYOM1 MYOM1 P52179 Myomesin-1 chr18 GO:0019900 Not Cancer Driver No 280 0.166 598 122 0.204 0
MYOM2 MYOM2 P54296 Myomesin-2 chr8 GO:0019900 Not Cancer Driver No 356 0.243 266 58 0.218 0
NAIP_ENST00000194097 NAIP Q13075 Baculoviral IAP repeat-containing protein 1 chr5 GO:0019900 Not Cancer Driver No 39 0.028 67 4 0.06 0
NBR1 NBR1 Q14596 Next to BRCA1 gene 1 protein chr17 GO:0019900 Not Cancer Driver No 101 0.105 560 51 0.091 0
NELL1_ENST00000357134 NELL1 Q92832 Protein kinase C-binding protein NELL1 chr11 GO:0019900 Not Cancer Driver No 238 0.294 7 3 0.429 0
NELL2_ENST00000452445 NELL2 Q99435 Protein kinase C-binding protein NELL2 chr12 GO:0019900 Not Cancer Driver No 194 0.238 15 4 0.267 0
NFATC1 NFATC1 O95644 Nuclear factor of activated T-cells, cytoplasmic 1 chr18 GO:0019900 Not Cancer Driver No 173 0.183 713 130 0.182 0
NIN NIN Q8N4C6 Ninein chr14 GO:0019900 Census, Compendium Yes 239 0.114 1392 164 0.118 2
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 GO:0019900 Census, Compendium Yes 168 0.211 57 8 0.14 25
PARD6A PARD6A Q9NPB6 Partitioning defective 6 homolog alpha chr16 GO:0019900 Not Cancer Driver No 25 0.072 177 13 0.073 0
PARD6B PARD6B Q9BYG5 Partitioning defective 6 homolog beta chr20 GO:0019900 Not Cancer Driver No 50 0.134 166 23 0.139 0
PARD6G PARD6G Q9BYG4 Partitioning defective 6 homolog gamma chr18 GO:0019900 Not Cancer Driver No 32 0.085 175 11 0.063 0
PARK7_ENST00000377488 PARK7 Q99497 Parkinson disease protein 7 chr1 GO:0019900 Not Cancer Driver No 11 0.058 30 0 0.0 5
PARP16 PARP16 Q8N5Y8 Protein mono-ADP-ribosyltransferase PARP16 chr15 GO:0019900 Not Cancer Driver No 37 0.115 33 3 0.091 0
PDE3B PDE3B Q13370 cGMP-inhibited 3',5'-cyclic phosphodiesterase B chr11 GO:0019900 Not Cancer Driver No 135 0.121 393 37 0.094 0
PDE8A_ENST00000394553 PDE8A O60658 High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A chr15 GO:0019900 Not Cancer Driver No 78 0.094 187 17 0.091 0
PDLIM5_ENST00000317968 PDLIM5 Q96HC4 PDZ and LIM domain protein 5 chr4 GO:0019900 Not Cancer Driver No 89 0.149 372 57 0.153 0
PER1 PER1 O15534 Period circadian protein homolog 1 chr17 GO:0019900 Census Yes 160 0.124 948 116 0.122 0
PER3_ENST00000361923 PER3 P56645 Period circadian protein homolog 3 chr1 GO:0019900 Not Cancer Driver No 170 0.142 710 100 0.141 0
PFKFB1 PFKFB1 P16118 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 chrX GO:0019900 Not Cancer Driver No 81 0.172 48 11 0.229 0
PFKL PFKL P17858 ATP-dependent 6-phosphofructokinase, liver type chr21 GO:0019900 Not Cancer Driver No 91 0.117 29 4 0.138 0
PFKM_ENST00000550924 PFKM P08237 ATP-dependent 6-phosphofructokinase, muscle type chr12 GO:0019900 Not Cancer Driver No 80 0.103 70 8 0.114 9
PICK1 PICK1 Q9NRD5 PRKCA-binding protein chr22 GO:0019900 Not Cancer Driver No 50 0.12 49 3 0.061 0
PIK3IP1 PIK3IP1 Q96FE7 Phosphoinositide-3-kinase-interacting protein 1 chr22 GO:0019900 Not Cancer Driver No 27 0.103 128 13 0.102 0
PIK3R1 PIK3R1 P27986 Phosphatidylinositol 3-kinase regulatory subunit alpha chr5 GO:0019900 Census, Compendium Yes 154 0.213 268 61 0.228 2
PIN1 PIN1 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 chr19 GO:0019900 Not Cancer Driver No 17 0.104 115 12 0.104 0
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 GO:0019900 Not Cancer Driver No 57 0.098 99 13 0.131 23
PIP5K1A PIP5K1A Q99755 Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha chr1 GO:0019900 Not Cancer Driver No 74 0.132 216 29 0.134 0
PJA2 PJA2 O43164 E3 ubiquitin-protein ligase Praja-2 chr5 GO:0019900 Not Cancer Driver No 80 0.113 598 66 0.11 0
PKIA PKIA P61925 cAMP-dependent protein kinase inhibitor alpha chr8 GO:0019900 Not Cancer Driver No 18 0.237 76 18 0.237 0
PKN1_ENST00000242783 PKN1 Q16512 Serine/threonine-protein kinase N1 chr19 GO:0019900 Not Cancer Driver No 120 0.127 459 54 0.118 0
PKP2 PKP2 Q99959 Plakophilin-2 chr12 GO:0019900 Not Cancer Driver No 176 0.2 434 98 0.226 8
PLEK PLEK P08567 Pleckstrin chr2 GO:0019900 Not Cancer Driver No 81 0.231 39 9 0.231 0
PLG PLG P00747 Plasminogen chr6 GO:0019900 Not Cancer Driver No 242 0.299 230 64 0.278 9
PLGLB2 PLGLB2 Q02325 Plasminogen-like protein B chr2 GO:0019900 Not Cancer Driver No 2 0.021 0 0 0.0 0
PPEF2 PPEF2 O14830 Serine/threonine-protein phosphatase with EF-hands 2 chr4 GO:0019900 Not Cancer Driver No 144 0.191 130 29 0.223 0
PPM1D PPM1D O15297 Protein phosphatase 1D chr17 GO:0019900 Census, Compendium Yes 54 0.089 370 32 0.086 0
PPP1R9B PPP1R9B Q96SB3 Neurabin-2 chr17 GO:0019900 Not Cancer Driver No 47 0.058 695 35 0.05 0
PPP2R5A PPP2R5A Q15172 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform chr1 GO:0019900 Not Cancer Driver No 55 0.113 93 5 0.054 0
PRDX3 PRDX3 P30048 Thioredoxin-dependent peroxide reductase, mitochondrial chr10 GO:0019900 Not Cancer Driver No 23 0.09 23 3 0.13 0
PRKAR1A_ENST00000536854 PRKAR1A P10644 cAMP-dependent protein kinase type I-alpha regulatory subunit chr17 GO:0019900 Census, Compendium Yes 39 0.102 66 11 0.167 17
PRKAR1B_ENST00000403562 PRKAR1B P31321 cAMP-dependent protein kinase type I-beta regulatory subunit chr7 GO:0019900 Not Cancer Driver No 53 0.139 71 13 0.183 0
PRKAR2A PRKAR2A P13861 cAMP-dependent protein kinase type II-alpha regulatory subunit chr3 GO:0019900 Not Cancer Driver No 37 0.092 149 13 0.087 0
PRKAR2B PRKAR2B P31323 cAMP-dependent protein kinase type II-beta regulatory subunit chr7 GO:0019900 Not Cancer Driver No 60 0.144 125 4 0.032 0
PRKCB_ENST00000321728 PRKCB P05771 Protein kinase C beta type chr16 GO:0019900 Census, Compendium Yes 205 0.306 148 40 0.27 0
PRKCD_ENST00000330452 PRKCD Q05655 Protein kinase C delta type chr3 GO:0019900 Compendium Yes 79 0.117 43 9 0.209 0
PRKCSH_ENST00000589838 PRKCSH P14314 Glucosidase 2 subunit beta chr19 GO:0019900 Not Cancer Driver No 68 0.129 320 41 0.128 0
PRKD2_ENST00000291281 PRKD2 Q9BZL6 Serine/threonine-protein kinase D2 chr19 GO:0019900 Compendium Yes 118 0.134 246 34 0.138 0
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 GO:0019900 Not Cancer Driver No 110 0.237 78 15 0.192 31
PRMT1 PRMT1 Q99873 Protein arginine N-methyltransferase 1 chr19 GO:0019900 Not Cancer Driver No 50 0.135 18 1 0.056 0
PTAFR_ENST00000305392 PTAFR P25105 Platelet-activating factor receptor chr1 GO:0019900 Not Cancer Driver No 42 0.123 0 0 0.0 0
PTK2B_ENST00000346049 PTK2B Q14289 Protein-tyrosine kinase 2-beta chr8 GO:0019900 Not Cancer Driver No 161 0.16 261 37 0.142 0
PTK2_ENST00000522684 PTK2 Q05397 Focal adhesion kinase 1 chr8 GO:0019900 Not Cancer Driver No 134 0.127 425 55 0.129 0
PTPN22 PTPN22 Q9Y2R2 Tyrosine-protein phosphatase non-receptor type 22 chr1 GO:0019900 Not Cancer Driver No 141 0.175 364 62 0.17 4
PTPRJ PTPRJ Q12913 Receptor-type tyrosine-protein phosphatase eta chr11 GO:0019900 Not Cancer Driver No 184 0.138 401 61 0.152 0
RACK1 RACK1 P63244 Receptor of activated protein C kinase 1 chr5 GO:0019900 Not Cancer Driver No 34 0.107 13 0 0.0 0
RAD23A RAD23A P54725 UV excision repair protein RAD23 homolog A chr19 GO:0019900 Not Cancer Driver No 50 0.138 283 41 0.145 0
RARA RARA P10276 Retinoic acid receptor alpha chr17 GO:0019900 Census, Compendium Yes 70 0.152 167 14 0.084 0
RASGRP3_ENST00000402538 RASGRP3 Q8IV61 Ras guanyl-releasing protein 3 chr2 GO:0019900 Not Cancer Driver No 119 0.172 145 20 0.138 0
RB1 RB1 P06400 Retinoblastoma-associated protein chr13 GO:0019900 Census, Compendium Yes 140 0.151 282 32 0.113 22
RNF13_ENST00000392894 RNF13 O43567 E3 ubiquitin-protein ligase RNF13 chr3 GO:0019900 Not Cancer Driver No 45 0.118 107 17 0.159 2
ROR2 ROR2 Q01974 Tyrosine-protein kinase transmembrane receptor ROR2 chr9 GO:0019900 Not Cancer Driver No 203 0.215 299 71 0.237 5
RPS3_ENST00000527446 RPS3 P23396 40S ribosomal protein S3 chr11 GO:0019900 Not Cancer Driver No 22 0.091 48 4 0.083 0
RYR2 RYR2 Q92736 Ryanodine receptor 2 chr1 GO:0019900 Not Cancer Driver No 1703 0.343 782 281 0.359 51
SASH1 SASH1 O94885 SAM and SH3 domain-containing protein 1 chr6 GO:0019900 Not Cancer Driver No 174 0.14 1071 153 0.143 7
SDC4 SDC4 P31431 Syndecan-4 chr20 GO:0019900 Census, Compendium Yes 34 0.172 110 25 0.227 0
SGO1 SGO1 Q5FBB7 Shugoshin 1 chr3 GO:0019900 Not Cancer Driver No 57 0.102 360 39 0.108 1
SH2B1 SH2B1 Q9NRF2 SH2B adapter protein 1 chr16 GO:0019900 Not Cancer Driver No 98 0.13 612 84 0.137 0
SH2B3 SH2B3 Q9UQQ2 SH2B adapter protein 3 chr12 GO:0019900 Census, Compendium Yes 48 0.083 333 19 0.057 0
SHC1_ENST00000368445 SHC1 P29353 SHC-transforming protein 1 chr1 GO:0019900 Not Cancer Driver No 84 0.144 397 58 0.146 0
SIRT1 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 GO:0019900 Not Cancer Driver No 70 0.094 435 31 0.071 0
SIT1 SIT1 Q9Y3P8 Signaling threshold-regulating transmembrane adapter 1 chr9 GO:0019900 Not Cancer Driver No 21 0.107 122 9 0.074 0
SLC2A1 SLC2A1 P11166 Solute carrier family 2, facilitated glucose transporter member 1 chr1 GO:0019900 Not Cancer Driver No 51 0.104 13 2 0.154 48
SNAI1 SNAI1 O95863 Zinc finger protein SNAI1 chr20 GO:0019900 Not Cancer Driver No 52 0.197 97 11 0.113 0
SOX9 SOX9 P48436 Transcription factor SOX-9 chr17 GO:0019900 Compendium Yes 86 0.169 495 82 0.166 18
SP100_ENST00000264052 SP100 P23497 Nuclear autoantigen Sp-100 chr2 GO:0019900 Not Cancer Driver No 136 0.155 680 101 0.149 0
SPAG9 SPAG9 O60271 C-Jun-amino-terminal kinase-interacting protein 4 chr17 GO:0019900 Not Cancer Driver No 128 0.097 841 81 0.096 0
SQSTM1 SQSTM1 Q13501 Sequestosome-1 chr5 GO:0019900 Not Cancer Driver No 54 0.123 267 32 0.12 30
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:0019900 Census Yes 53 0.099 130 11 0.085 1
SRSF2 SRSF2 Q01130 Serine/arginine-rich splicing factor 2 chr17 GO:0019900 Census, Compendium Yes 38 0.172 219 38 0.174 0
SRSF5_ENST00000557154 SRSF5 Q13243 Serine/arginine-rich splicing factor 5 chr14 GO:0019900 Not Cancer Driver No 50 0.184 189 40 0.212 0
STAP1_ENST00000396225 STAP1 Q9ULZ2 Signal-transducing adaptor protein 1 chr4 GO:0019900 Not Cancer Driver No 66 0.224 103 18 0.175 0
STAU2 STAU2 Q9NUL3 Double-stranded RNA-binding protein Staufen homolog 2 chr8 GO:0019900 Not Cancer Driver No 68 0.119 486 54 0.111 0
STK38 STK38 Q15208 Serine/threonine-protein kinase 38 chr6 GO:0019900 Not Cancer Driver No 57 0.123 77 6 0.078 0
STRADA STRADA Q7RTN6 STE20-related kinase adapter protein alpha chr17 GO:0019900 Not Cancer Driver No 49 0.114 118 14 0.119 0
STUB1 STUB1 Q9UNE7 E3 ubiquitin-protein ligase CHIP chr16 GO:0019900 Not Cancer Driver No 35 0.116 112 14 0.125 12
STX1A STX1A Q16623 Syntaxin-1A chr7 GO:0019900 Not Cancer Driver No 35 0.122 136 11 0.081 0
TAB1 TAB1 Q15750 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 chr22 GO:0019900 Not Cancer Driver No 81 0.161 232 34 0.147 0
TAOK2 TAOK2 Q9UL54 Serine/threonine-protein kinase TAO2 chr16 GO:0019900 Not Cancer Driver No 191 0.155 666 102 0.153 0
TAX1BP1 TAX1BP1 Q86VP1 Tax1-binding protein 1 chr7 GO:0019900 Not Cancer Driver No 78 0.099 429 50 0.117 0
TCF3 TCF3 P15923 Transcription factor E2-alpha chr19 GO:0019900 Census Yes 52 0.08 649 52 0.08 0
TDG TDG Q13569 G/T mismatch-specific thymine DNA glycosylase chr12 GO:0019900 Not Cancer Driver No 75 0.183 185 31 0.168 0
TGFBR2_ENST00000295754 TGFBR2 P37173 TGF-beta receptor type-2 chr3 GO:0019900 Census, Compendium Yes 106 0.187 60 16 0.267 25
TIAM1 TIAM1 Q13009 Rho guanine nucleotide exchange factor TIAM1 chr21 GO:0019900 Not Cancer Driver No 370 0.233 810 194 0.24 0
TIRAP_ENST00000392680 TIRAP P58753 Toll/interleukin-1 receptor domain-containing adapter protein chr11 GO:0019900 Not Cancer Driver No 28 0.127 80 6 0.075 0
TNFAIP3 TNFAIP3 P21580 Tumor necrosis factor alpha-induced protein 3 chr6 GO:0019900 Census, Compendium Yes 98 0.124 231 33 0.143 1
TNIP1_ENST00000522226 TNIP1 Q15025 TNFAIP3-interacting protein 1 chr5 GO:0019900 Not Cancer Driver No 85 0.134 625 83 0.133 0
TNS2_ENST00000314250 TNS2 Q63HR2 Tensin-2 chr12 GO:0019900 Not Cancer Driver No 132 0.094 799 63 0.079 0
TOLLIP TOLLIP Q9H0E2 Toll-interacting protein chr11 GO:0019900 Not Cancer Driver No 38 0.139 81 12 0.148 0
TOP2A TOP2A P11388 DNA topoisomerase 2-alpha chr17 GO:0019900 Compendium Yes 150 0.098 508 59 0.116 0
TOP2B TOP2B Q02880 DNA topoisomerase 2-beta chr3 GO:0019900 Not Cancer Driver No 154 0.095 543 46 0.085 0
TPR TPR P12270 Nucleoprotein TPR chr1 GO:0019900 Census Yes 311 0.132 1990 266 0.134 0
TRADD TRADD Q15628 Tumor necrosis factor receptor type 1-associated DEATH domain protein chr16 GO:0019900 Not Cancer Driver No 26 0.083 74 5 0.068 0
TRAF2 TRAF2 Q12933 TNF receptor-associated factor 2 chr9 GO:0019900 Not Cancer Driver No 63 0.126 4 1 0.25 0
TRAF6_ENST00000348124 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 GO:0019900 Not Cancer Driver No 67 0.128 62 7 0.113 0
TRAT1 TRAT1 Q6PIZ9 T-cell receptor-associated transmembrane adapter 1 chr3 GO:0019900 Not Cancer Driver No 86 0.462 129 67 0.519 0
TRIB1 TRIB1 Q96RU8 Tribbles homolog 1 chr8 GO:0019900 Not Cancer Driver No 47 0.126 91 5 0.055 0
TRIB2 TRIB2 Q92519 Tribbles homolog 2 chr2 GO:0019900 Not Cancer Driver No 64 0.187 43 5 0.116 0
TRIB3_ENST00000217233 TRIB3 Q96RU7 Tribbles homolog 3 chr20 GO:0019900 Not Cancer Driver No 65 0.182 114 24 0.211 0
TRIP6 TRIP6 Q15654 Thyroid receptor-interacting protein 6 chr7 GO:0019900 Not Cancer Driver No 62 0.13 268 19 0.071 0
TRPV4 TRPV4 Q9HBA0 Transient receptor potential cation channel subfamily V member 4 chr12 GO:0019900 Not Cancer Driver No 142 0.163 231 34 0.147 44
TTC28 TTC28 Q96AY4 Tetratricopeptide repeat protein 28 chr22 GO:0019900 Not Cancer Driver No 109 0.044 844 38 0.045 0
TWF2 TWF2 Q6IBS0 Twinfilin-2 chr3 GO:0019900 Not Cancer Driver No 34 0.097 59 8 0.136 0
UBQLN1 UBQLN1 Q9UMX0 Ubiquilin-1 chr9 GO:0019900 Not Cancer Driver No 64 0.109 543 58 0.107 0
UGT1A10 UGT1A10 Q9HAW8 UDP-glucuronosyltransferase 1A10 chr2 GO:0019900 Not Cancer Driver No 114 0.215 11 2 0.182 0
UGT1A7 UGT1A7 Q9HAW7 UDP-glucuronosyltransferase 1A7 chr2 GO:0019900 Not Cancer Driver No 110 0.208 11 2 0.182 0
WDCP WDCP Q9H6R7 WD repeat and coiled-coil-containing protein chr2 GO:0019900 Census Yes 77 0.107 126 9 0.071 0
WWC1_ENST00000265293 WWC1 Q8IX03 Protein KIBRA chr5 GO:0019900 Not Cancer Driver No 147 0.132 550 81 0.147 0
WWC2 WWC2 Q6AWC2 Protein WWC2 chr4 GO:0019900 Not Cancer Driver No 120 0.101 654 79 0.121 0
WWC3 WWC3 Q9ULE0 Protein WWC3 chrX GO:0019900 Not Cancer Driver No 214 0.196 638 114 0.179 0
XIAP_ENST00000434753 XIAP P98170 E3 ubiquitin-protein ligase XIAP chrX GO:0019900 Not Cancer Driver No 89 0.179 55 6 0.109 0
YWHAG YWHAG P61981 14-3-3 protein gamma chr7 GO:0019900 Not Cancer Driver No 26 0.105 77 9 0.117 2