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Total number of protein in "GO:0019838" GO term:  121

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
A2M A2M P01023 Alpha-2-macroglobulin chr12 GO:0019838 Not Cancer Driver No 260 0.176 144 22 0.153 0
ACVR1B_ENST00000257963 ACVR1B P36896 Activin receptor type-1B chr12 GO:0019838 Census Yes 114 0.226 0 0 0.0 0
ACVR1C ACVR1C Q8NER5 Activin receptor type-1C chr2 GO:0019838 Not Cancer Driver No 90 0.183 3 1 0.333 0
ACVR1_ENST00000434821 ACVR1 Q04771 Activin receptor type-1 chr2 GO:0019838 Census, Compendium Yes 78 0.153 21 8 0.381 8
ACVR2A_ENST00000404590 ACVR2A P27037 Activin receptor type-2A chr2 GO:0019838 Census, Compendium Yes 98 0.191 56 6 0.107 0
ACVR2B ACVR2B Q13705 Activin receptor type-2B chr3 GO:0019838 Not Cancer Driver No 83 0.162 70 14 0.2 2
ACVRL1 ACVRL1 P37023 Serine/threonine-protein kinase receptor R3 chr12 GO:0019838 Not Cancer Driver No 93 0.185 60 11 0.183 82
CCN1 CCN1 O00622 CCN family member 1 chr1 GO:0019838 Not Cancer Driver No 33 0.087 12 0 0.0 0
CCN2 CCN2 P29279 CCN family member 2 chr6 GO:0019838 Not Cancer Driver No 58 0.166 0 0 0.0 0
CCN3 CCN3 P48745 CCN family member 3 chr8 GO:0019838 Not Cancer Driver No 66 0.185 19 1 0.053 0
CCN4 CCN4 O95388 CCN family member 4 chr8 GO:0019838 Not Cancer Driver No 93 0.253 20 8 0.4 0
CCN5_ENST00000190983 CCN5 O76076 CCN family member 5 chr20 GO:0019838 Not Cancer Driver No 43 0.172 22 4 0.182 0
CCN6_ENST00000230529 CCN6 O95389 Cellular communication network factor 6 chr6 GO:0019838 Not Cancer Driver No 39 0.11 11 0 0.0 9
CD109 CD109 Q6YHK3 CD109 antigen chr6 GO:0019838 Not Cancer Driver No 204 0.141 54 11 0.204 0
CD36_ENST00000309881 CD36 P16671 Platelet glycoprotein 4 chr7 GO:0019838 Not Cancer Driver No 75 0.159 12 3 0.25 3
COL1A1 COL1A1 P02452 Collagen alpha-1(I) chain chr17 GO:0019838 Census, Compendium Yes 247 0.169 1212 214 0.177 148
COL1A2 COL1A2 P08123 Collagen alpha-2(I) chain chr7 GO:0019838 Not Cancer Driver No 372 0.272 1159 329 0.284 83
COL2A1 COL2A1 P02458 Collagen alpha-1(II) chain chr12 GO:0019838 Census Yes 258 0.174 1215 207 0.17 64
COL3A1 COL3A1 P02461 Collagen alpha-1(III) chain chr2 GO:0019838 Census Yes 402 0.274 1182 337 0.285 103
COL4A1 COL4A1 P02462 Collagen alpha-1(IV) chain chr13 GO:0019838 Not Cancer Driver No 349 0.209 1457 310 0.213 32
COL5A1 COL5A1 P20908 Collagen alpha-1(V) chain chr9 GO:0019838 Not Cancer Driver No 451 0.245 1456 385 0.264 7
COL6A1 COL6A1 P12109 Collagen alpha-1(VI) chain chr21 GO:0019838 Not Cancer Driver No 145 0.141 434 61 0.141 12
CRIM1 CRIM1 Q9NZV1 Cysteine-rich motor neuron 1 protein chr2 GO:0019838 Not Cancer Driver No 133 0.128 35 4 0.114 0
EGFR EGFR P00533 Epidermal growth factor receptor chr7 GO:0019838 Census, Compendium Yes 444 0.367 223 35 0.157 1
ENG ENG P17813 Endoglin chr9 GO:0019838 Not Cancer Driver No 60 0.091 114 15 0.132 32
EPHA2 EPHA2 P29317 Ephrin type-A receptor 2 chr1 GO:0019838 Compendium Yes 171 0.175 187 39 0.209 3
EPHA7 EPHA7 Q15375 Ephrin type-A receptor 7 chr6 GO:0019838 Census, Compendium Yes 280 0.281 71 15 0.211 0
EPHA8 EPHA8 P29322 Ephrin type-A receptor 8 chr1 GO:0019838 Not Cancer Driver No 197 0.196 121 17 0.14 0
ERBB2 ERBB2 P04626 Receptor tyrosine-protein kinase erbB-2 chr17 GO:0019838 Census, Compendium Yes 275 0.219 314 41 0.131 1
ERBB3 ERBB3 P21860 Receptor tyrosine-protein kinase erbB-3 chr12 GO:0019838 Census, Compendium Yes 298 0.222 396 70 0.177 3
ESM1 ESM1 Q9NQ30 Endothelial cell-specific molecule 1 chr5 GO:0019838 Not Cancer Driver No 44 0.239 37 11 0.297 0
FGFBP1 FGFBP1 Q14512 Fibroblast growth factor-binding protein 1 chr4 GO:0019838 Not Cancer Driver No 28 0.12 81 8 0.099 0
FGFBP2 FGFBP2 Q9BYJ0 Fibroblast growth factor-binding protein 2 chr4 GO:0019838 Not Cancer Driver No 28 0.126 149 21 0.141 0
FGFBP3 FGFBP3 Q8TAT2 Fibroblast growth factor-binding protein 3 chr10 GO:0019838 Not Cancer Driver No 6 0.023 175 3 0.017 0
FLT1 FLT1 P17948 Vascular endothelial growth factor receptor 1 chr13 GO:0019838 Not Cancer Driver No 299 0.223 103 20 0.194 0
FLT3 FLT3 P36888 Receptor-type tyrosine-protein kinase FLT3 chr13 GO:0019838 Census, Compendium Yes 200 0.201 64 27 0.422 0
FLT4 FLT4 P35916 Vascular endothelial growth factor receptor 3 chr5 GO:0019838 Census, Compendium Yes 253 0.186 259 41 0.158 13
FSTL4 FSTL4 Q6MZW2 Follistatin-related protein 4 chr5 GO:0019838 Not Cancer Driver No 134 0.159 96 12 0.125 0
FURIN_ENST00000610579 FURIN P09958 Furin chr15 GO:0019838 Not Cancer Driver No 93 0.117 283 35 0.124 0
GHRHR GHRHR Q02643 Growth hormone-releasing hormone receptor chr7 GO:0019838 Not Cancer Driver No 41 0.097 3 0 0.0 5
GHR_ENST00000612382 GHR P10912 Growth hormone receptor chr5 GO:0019838 Not Cancer Driver No 173 0.271 229 66 0.288 19
HAP1_ENST00000310778 HAP1 P54257 Huntingtin-associated protein 1 chr17 GO:0019838 Not Cancer Driver No 97 0.145 454 60 0.132 0
HAX1 HAX1 O00165 HCLS1-associated protein X-1 chr1 GO:0019838 Not Cancer Driver No 44 0.158 219 32 0.146 2
HTRA1 HTRA1 Q92743 Serine protease HTRA1 chr10 GO:0019838 Not Cancer Driver No 77 0.16 40 9 0.225 11
HTRA3 HTRA3 P83110 Serine protease HTRA3 chr4 GO:0019838 Not Cancer Driver No 64 0.141 57 11 0.193 0
HTRA4 HTRA4 P83105 Serine protease HTRA4 chr8 GO:0019838 Not Cancer Driver No 57 0.12 15 0 0.0 0
HYAL2_ENST00000357750 HYAL2 Q12891 Hyaluronidase-2 chr3 GO:0019838 Not Cancer Driver No 52 0.11 8 1 0.125 0
IGF1R IGF1R P08069 Insulin-like growth factor 1 receptor chr15 GO:0019838 Not Cancer Driver No 183 0.134 265 37 0.14 6
IGF2R IGF2R P11717 Cation-independent mannose-6-phosphate receptor chr6 GO:0019838 Not Cancer Driver No 318 0.128 255 20 0.078 0
IGFALS_ENST00000215539 IGFALS P35858 Insulin-like growth factor-binding protein complex acid labile subunit chr16 GO:0019838 Not Cancer Driver No 50 0.083 14 4 0.286 8
IGFBP1 IGFBP1 P08833 Insulin-like growth factor-binding protein 1 chr7 GO:0019838 Not Cancer Driver No 47 0.181 42 7 0.167 0
IGFBP2 IGFBP2 P18065 Insulin-like growth factor-binding protein 2 chr2 GO:0019838 Not Cancer Driver No 32 0.098 171 24 0.14 0
IGFBP3_ENST00000275521 IGFBP3 P17936 Insulin-like growth factor-binding protein 3 chr7 GO:0019838 Not Cancer Driver No 41 0.141 103 25 0.243 0
IGFBP4 IGFBP4 P22692 Insulin-like growth factor-binding protein 4 chr17 GO:0019838 Not Cancer Driver No 24 0.093 106 17 0.16 0
IGFBP5 IGFBP5 P24593 Insulin-like growth factor-binding protein 5 chr2 GO:0019838 Not Cancer Driver No 27 0.099 112 17 0.152 0
IGFBP6 IGFBP6 P24592 Insulin-like growth factor-binding protein 6 chr12 GO:0019838 Not Cancer Driver No 22 0.092 166 18 0.108 0
IGFBP7 IGFBP7 Q16270 Insulin-like growth factor-binding protein 7 chr4 GO:0019838 Not Cancer Driver No 22 0.078 100 12 0.12 0
IGFBPL1 IGFBPL1 Q8WX77 Insulin-like growth factor-binding protein-like 1 chr9 GO:0019838 Not Cancer Driver No 31 0.112 75 12 0.16 0
IL10RA IL10RA Q13651 Interleukin-10 receptor subunit alpha chr11 GO:0019838 Not Cancer Driver No 77 0.133 220 26 0.118 7
IL11RA_ENST00000441545 IL11RA Q14626 Interleukin-11 receptor subunit alpha chr9 GO:0019838 Not Cancer Driver No 48 0.114 153 11 0.072 3
IL1R1 IL1R1 P14778 Interleukin-1 receptor type 1 chr2 GO:0019838 Not Cancer Driver No 77 0.135 59 8 0.136 0
IL1R2_ENST00000393414 IL1R2 P27930 Interleukin-1 receptor type 2 chr2 GO:0019838 Not Cancer Driver No 75 0.188 32 10 0.312 0
IL1RAPL1 IL1RAPL1 Q9NZN1 Interleukin-1 receptor accessory protein-like 1 chrX GO:0019838 Not Cancer Driver No 205 0.295 77 19 0.247 0
IL1RN_ENST00000409930 IL1RN P18510 Interleukin-1 receptor antagonist protein chr2 GO:0019838 Not Cancer Driver No 34 0.192 17 7 0.412 0
IL2RA IL2RA P01589 Interleukin-2 receptor subunit alpha chr10 GO:0019838 Not Cancer Driver No 51 0.188 131 29 0.221 2
IL2RB IL2RB P14784 Interleukin-2 receptor subunit beta chr22 GO:0019838 Not Cancer Driver No 81 0.147 182 33 0.181 1
IL2RG IL2RG P31785 Cytokine receptor common subunit gamma chrX GO:0019838 Not Cancer Driver No 56 0.152 32 6 0.188 33
IL36RN_ENST00000346807 IL36RN Q9UBH0 Interleukin-36 receptor antagonist protein chr2 GO:0019838 Not Cancer Driver No 34 0.219 7 4 0.571 4
IL6R IL6R P08887 Interleukin-6 receptor subunit alpha chr1 GO:0019838 Not Cancer Driver No 55 0.118 165 23 0.139 1
IL6ST_ENST00000336909 IL6ST P40189 Interleukin-6 receptor subunit beta chr5 GO:0019838 Census, Compendium Yes 102 0.111 315 40 0.127 2
IL9R IL9R Q01113 Interleukin-9 receptor chrX GO:0019838 Not Cancer Driver No 96 0.184 78 18 0.231 0
INSR INSR P06213 Insulin receptor chr19 GO:0019838 Not Cancer Driver No 190 0.137 280 57 0.204 64
ITGA6_ENST00000442250 ITGA6 P23229 Integrin alpha-6 chr2 GO:0019838 Not Cancer Driver No 130 0.115 226 29 0.128 0
ITGAV ITGAV P06756 Integrin alpha-V chr2 GO:0019838 Census Yes 153 0.146 92 9 0.098 0
ITGB3 ITGB3 P05106 Integrin beta-3 chr17 GO:0019838 Not Cancer Driver No 124 0.157 66 5 0.076 30
ITGB4 ITGB4 P16144 Integrin beta-4 chr17 GO:0019838 Not Cancer Driver No 248 0.136 753 86 0.114 14
KAZALD1 KAZALD1 Q96I82 Kazal-type serine protease inhibitor domain-containing protein 1 chr10 GO:0019838 Not Cancer Driver No 26 0.086 106 13 0.123 0
KDR KDR P35968 Vascular endothelial growth factor receptor 2 chr4 GO:0019838 Census, Compendium Yes 357 0.263 275 55 0.2 2
LIFR_ENST00000453190 LIFR P42702 Leukemia inhibitory factor receptor chr5 GO:0019838 Census, Compendium Yes 247 0.225 259 56 0.216 1
LRP2 LRP2 P98164 Low-density lipoprotein receptor-related protein 2 chr2 GO:0019838 Not Cancer Driver No 998 0.214 209 40 0.191 1
LRRC32_ENST00000404995 LRRC32 Q14392 Transforming growth factor beta activator LRRC32 chr11 GO:0019838 Not Cancer Driver No 130 0.196 28 4 0.143 0
LTBP1 LTBP1 Q14766 Latent-transforming growth factor beta-binding protein 1 chr2 GO:0019838 Not Cancer Driver No 300 0.174 518 78 0.151 0
LTBP2 LTBP2 Q14767 Latent-transforming growth factor beta-binding protein 2 chr14 GO:0019838 Not Cancer Driver No 302 0.166 632 102 0.161 1
LTBP3 LTBP3 Q9NS15 Latent-transforming growth factor beta-binding protein 3 chr11 GO:0019838 Not Cancer Driver No 108 0.083 356 22 0.062 0
LTBP4 LTBP4 Q8N2S1 Latent-transforming growth factor beta-binding protein 4 chr19 GO:0019838 Not Cancer Driver No 191 0.118 432 42 0.097 1
NGFR NGFR P08138 Tumor necrosis factor receptor superfamily member 16 chr17 GO:0019838 Not Cancer Driver No 57 0.133 172 25 0.145 0
NKD2 NKD2 Q969F2 Protein naked cuticle homolog 2 chr5 GO:0019838 Not Cancer Driver No 64 0.142 451 64 0.142 0
NLRP7_ENST00000590030 NLRP7 Q8WX94 NACHT, LRR and PYD domains-containing protein 7 chr19 GO:0019838 Not Cancer Driver No 300 0.306 71 20 0.282 9
NRDC_ENST00000352171 NRDC O43847 Nardilysin chr1 GO:0019838 Not Cancer Driver No 162 0.141 253 34 0.134 0
NRP1 NRP1 O14786 Neuropilin-1 chr10 GO:0019838 Compendium Yes 146 0.158 211 31 0.147 0
NRP2 NRP2 O60462 Neuropilin-2 chr2 GO:0019838 Not Cancer Driver No 161 0.173 207 45 0.217 0
NRROS NRROS Q86YC3 Transforming growth factor beta activator LRRC33 chr3 GO:0019838 Not Cancer Driver No 109 0.158 8 1 0.125 0
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 GO:0019838 Census, Compendium Yes 168 0.211 57 8 0.14 25
NTRK2_ENST00000323115 NTRK2 Q16620 BDNF/NT-3 growth factors receptor chr9 GO:0019838 Not Cancer Driver No 155 0.189 117 18 0.154 1
NTRK3_ENST00000629765 NTRK3 Q16288 NT-3 growth factor receptor chr15 GO:0019838 Census, Compendium Yes 249 0.297 57 21 0.368 0
OSMR OSMR Q99650 Oncostatin-M-specific receptor subunit beta chr5 GO:0019838 Not Cancer Driver No 167 0.171 145 22 0.152 5
PCSK6 PCSK6 P29122 Proprotein convertase subtilisin/kexin type 6 chr15 GO:0019838 Not Cancer Driver No 138 0.142 207 45 0.217 0
PDGFA PDGFA P04085 Platelet-derived growth factor subunit A chr7 GO:0019838 Not Cancer Driver No 31 0.147 75 10 0.133 0
PDGFB PDGFB P01127 Platelet-derived growth factor subunit B chr22 GO:0019838 Census Yes 37 0.154 99 22 0.222 2
PDGFRA PDGFRA P16234 Platelet-derived growth factor receptor alpha chr4 GO:0019838 Census, Compendium Yes 290 0.266 173 45 0.26 2
PDGFRB PDGFRB P09619 Platelet-derived growth factor receptor beta chr5 GO:0019838 Census, Compendium Yes 164 0.148 231 44 0.19 7
PXDN PXDN Q92626 Peroxidasin homolog chr2 GO:0019838 Not Cancer Driver No 332 0.224 307 77 0.251 1
RHBDF1 RHBDF1 Q96CC6 Inactive rhomboid protein 1 chr16 GO:0019838 Not Cancer Driver No 96 0.112 316 44 0.139 0
RHBDF2 RHBDF2 Q6PJF5 Inactive rhomboid protein 2 chr17 GO:0019838 Not Cancer Driver No 93 0.109 284 36 0.127 2
SDCBP_ENST00000260130 SDCBP O00560 Syntenin-1 chr8 GO:0019838 Not Cancer Driver No 39 0.131 17 2 0.118 0
SEC61B SEC61B P60468 Protein transport protein Sec61 subunit beta chr9 GO:0019838 Not Cancer Driver No 11 0.115 60 7 0.117 0
SHC1_ENST00000368445 SHC1 P29353 SHC-transforming protein 1 chr1 GO:0019838 Not Cancer Driver No 84 0.144 397 58 0.146 0
SORT1 SORT1 Q99523 Sortilin chr1 GO:0019838 Not Cancer Driver No 69 0.083 110 2 0.018 0
SPINT3 SPINT3 P49223 Kunitz-type protease inhibitor 3 chr20 GO:0019838 Not Cancer Driver No 7 0.079 0 0 0.0 0
SRPX2 SRPX2 O60687 Sushi repeat-containing protein SRPX2 chrX GO:0019838 Not Cancer Driver No 86 0.185 64 13 0.203 0
TGFB3 TGFB3 P10600 Transforming growth factor beta-3 proprotein chr14 GO:0019838 Not Cancer Driver No 45 0.109 96 14 0.146 1
TGFBR1_ENST00000374994 TGFBR1 P36897 TGF-beta receptor type-1 chr9 GO:0019838 Not Cancer Driver No 86 0.171 23 3 0.13 15
TGFBR2_ENST00000295754 TGFBR2 P37173 TGF-beta receptor type-2 chr3 GO:0019838 Census, Compendium Yes 106 0.187 60 16 0.267 25
TGFBR3_ENST00000525962 TGFBR3 Q03167 Transforming growth factor beta receptor type 3 chr1 GO:0019838 Not Cancer Driver No 129 0.152 268 41 0.153 0
THBS1 THBS1 P07996 Thrombospondin-1 chr15 GO:0019838 Not Cancer Driver No 188 0.161 320 58 0.181 0
TRIM16_ENST00000336708 TRIM16 O95361 Tripartite motif-containing protein 16 chr17 GO:0019838 Not Cancer Driver No 64 0.113 132 11 0.083 0
TSKU_ENST00000333090 TSKU Q8WUA8 Tsukushi chr11 GO:0019838 Not Cancer Driver No 53 0.15 44 6 0.136 0
TWSG1 TWSG1 Q9GZX9 Twisted gastrulation protein homolog 1 chr18 GO:0019838 Not Cancer Driver No 27 0.121 19 3 0.158 0
VASN VASN Q6EMK4 Vasorin chr16 GO:0019838 Not Cancer Driver No 37 0.055 233 8 0.034 0
WFIKKN1 WFIKKN1 Q96NZ8 WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 1 chr16 GO:0019838 Not Cancer Driver No 38 0.069 90 4 0.044 0
WFIKKN2 WFIKKN2 Q8TEU8 WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 chr17 GO:0019838 Not Cancer Driver No 114 0.198 94 32 0.34 0