Total number of protein in "GO:0019787" GO term: 83
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKTIP_ENST00000570004 | AKTIP | Q9H8T0 | AKT-interacting protein | chr16 | GO:0019787 | Not Cancer Driver | No | 33 | 0.113 | 95 | 10 | 0.105 | 0 |
| AMFR | AMFR | Q9UKV5 | E3 ubiquitin-protein ligase AMFR | chr16 | GO:0019787 | Not Cancer Driver | No | 73 | 0.114 | 229 | 30 | 0.131 | 0 |
| ANAPC11_ENST00000579978 | ANAPC11 | Q9NYG5 | Anaphase-promoting complex subunit 11 | chr17 | GO:0019787 | Not Cancer Driver | No | 7 | 0.083 | 0 | 0 | 0.0 | 0 |
| ARIH1 | ARIH1 | Q9Y4X5 | E3 ubiquitin-protein ligase ARIH1 | chr15 | GO:0019787 | Not Cancer Driver | No | 46 | 0.083 | 119 | 7 | 0.059 | 0 |
| ATG16L1 | ATG16L1 | Q676U5 | Autophagy-related protein 16-1 | chr2 | GO:0019787 | Not Cancer Driver | No | 79 | 0.13 | 239 | 25 | 0.105 | 1 |
| ATG3 | ATG3 | Q9NT62 | Ubiquitin-like-conjugating enzyme ATG3 | chr3 | GO:0019787 | Not Cancer Driver | No | 29 | 0.092 | 110 | 9 | 0.082 | 0 |
| BIRC6 | BIRC6 | Q9NR09 | Baculoviral IAP repeat-containing protein 6 | chr2 | GO:0019787 | Census, Compendium | Yes | 640 | 0.132 | 1312 | 170 | 0.13 | 0 |
| CBX4 | CBX4 | O00257 | E3 SUMO-protein ligase CBX4 | chr17 | GO:0019787 | Not Cancer Driver | No | 72 | 0.129 | 477 | 63 | 0.132 | 0 |
| CDC34 | CDC34 | P49427 | Ubiquitin-conjugating enzyme E2 R1 | chr19 | GO:0019787 | Not Cancer Driver | No | 26 | 0.11 | 95 | 11 | 0.116 | 0 |
| EGR2 | EGR2 | P11161 | E3 SUMO-protein ligase EGR2 | chr10 | GO:0019787 | Compendium | Yes | 90 | 0.189 | 352 | 59 | 0.168 | 11 |
| HDAC4 | HDAC4 | P56524 | Histone deacetylase 4 | chr2 | GO:0019787 | Not Cancer Driver | No | 182 | 0.168 | 749 | 132 | 0.176 | 0 |
| HDAC7_ENST00000427332 | HDAC7 | Q8WUI4 | Histone deacetylase 7 | chr12 | GO:0019787 | Not Cancer Driver | No | 91 | 0.096 | 570 | 50 | 0.088 | 0 |
| HERC5 | HERC5 | Q9UII4 | E3 ISG15--protein ligase HERC5 | chr4 | GO:0019787 | Not Cancer Driver | No | 124 | 0.121 | 118 | 12 | 0.102 | 0 |
| ITCH | ITCH | Q96J02 | E3 ubiquitin-protein ligase Itchy homolog | chr20 | GO:0019787 | Not Cancer Driver | No | 95 | 0.105 | 335 | 42 | 0.125 | 0 |
| KIAA1586 | KIAA1586 | Q9HCI6 | E3 SUMO-protein ligase KIAA1586 | chr6 | GO:0019787 | Not Cancer Driver | No | 87 | 0.111 | 129 | 14 | 0.109 | 0 |
| MDM2_ENST00000539479 | MDM2 | Q00987 | E3 ubiquitin-protein ligase Mdm2 | chr12 | GO:0019787 | Census, Compendium | Yes | 56 | 0.114 | 297 | 37 | 0.125 | 0 |
| MUL1 | MUL1 | Q969V5 | Mitochondrial ubiquitin ligase activator of NFKB 1 | chr1 | GO:0019787 | Not Cancer Driver | No | 48 | 0.136 | 16 | 2 | 0.125 | 0 |
| NSMCE2_ENST00000522563 | NSMCE2 | Q96MF7 | E3 SUMO-protein ligase NSE2 | chr8 | GO:0019787 | Not Cancer Driver | No | 30 | 0.121 | 119 | 12 | 0.101 | 0 |
| PELI1 | PELI1 | Q96FA3 | E3 ubiquitin-protein ligase pellino homolog 1 | chr2 | GO:0019787 | Not Cancer Driver | No | 47 | 0.112 | 167 | 17 | 0.102 | 0 |
| PELI2 | PELI2 | Q9HAT8 | E3 ubiquitin-protein ligase pellino homolog 2 | chr14 | GO:0019787 | Not Cancer Driver | No | 80 | 0.19 | 162 | 38 | 0.235 | 0 |
| PIAS1_ENST00000249636 | PIAS1 | O75925 | E3 SUMO-protein ligase PIAS1 | chr15 | GO:0019787 | Not Cancer Driver | No | 80 | 0.123 | 241 | 43 | 0.178 | 0 |
| PIAS2 | PIAS2 | O75928 | E3 SUMO-protein ligase PIAS2 | chr18 | GO:0019787 | Not Cancer Driver | No | 78 | 0.126 | 209 | 28 | 0.134 | 0 |
| PIAS3 | PIAS3 | Q9Y6X2 | E3 SUMO-protein ligase PIAS3 | chr1 | GO:0019787 | Not Cancer Driver | No | 70 | 0.111 | 266 | 31 | 0.117 | 0 |
| PIAS4 | PIAS4 | Q8N2W9 | E3 SUMO-protein ligase PIAS4 | chr19 | GO:0019787 | Not Cancer Driver | No | 58 | 0.114 | 142 | 23 | 0.162 | 0 |
| PML | PML | P29590 | Protein PML | chr15 | GO:0019787 | Census, Compendium | Yes | 112 | 0.127 | 312 | 34 | 0.109 | 0 |
| PPIL2_ENST00000335025 | PPIL2 | Q13356 | RING-type E3 ubiquitin-protein ligase PPIL2 | chr22 | GO:0019787 | Not Cancer Driver | No | 64 | 0.123 | 212 | 19 | 0.09 | 0 |
| PRPF19 | PRPF19 | Q9UMS4 | Pre-mRNA-processing factor 19 | chr11 | GO:0019787 | Not Cancer Driver | No | 71 | 0.141 | 109 | 16 | 0.147 | 0 |
| RANBP2 | RANBP2 | P49792 | E3 SUMO-protein ligase RanBP2 | chr2 | GO:0019787 | Census, Compendium | Yes | 427 | 0.132 | 1387 | 177 | 0.128 | 3 |
| RBX1 | RBX1 | P62877 | E3 ubiquitin-protein ligase RBX1 | chr22 | GO:0019787 | Not Cancer Driver | No | 10 | 0.093 | 18 | 1 | 0.056 | 0 |
| RNF139 | RNF139 | Q8WU17 | E3 ubiquitin-protein ligase RNF139 | chr8 | GO:0019787 | Not Cancer Driver | No | 76 | 0.114 | 68 | 4 | 0.059 | 0 |
| RNF14 | RNF14 | Q9UBS8 | E3 ubiquitin-protein ligase RNF14 | chr5 | GO:0019787 | Not Cancer Driver | No | 52 | 0.11 | 40 | 8 | 0.2 | 0 |
| RNF212 | RNF212 | Q495C1 | Probable E3 SUMO-protein ligase RNF212 | chr4 | GO:0019787 | Not Cancer Driver | No | 36 | 0.121 | 58 | 12 | 0.207 | 0 |
| RNF212B | RNF212B | A8MTL3 | RING finger protein 212B | chr14 | GO:0019787 | Not Cancer Driver | No | 1 | 0.003 | 173 | 1 | 0.006 | 0 |
| RNF7 | RNF7 | Q9UBF6 | RING-box protein 2 | chr3 | GO:0019787 | Not Cancer Driver | No | 17 | 0.15 | 0 | 0 | 0.0 | 0 |
| STUB1 | STUB1 | Q9UNE7 | E3 ubiquitin-protein ligase CHIP | chr16 | GO:0019787 | Not Cancer Driver | No | 35 | 0.116 | 112 | 14 | 0.125 | 12 |
| TAF1_ENST00000373790 | TAF1 | P21675 | Transcription initiation factor TFIID subunit 1 | chrX | GO:0019787 | Not Cancer Driver | No | 379 | 0.202 | 1152 | 219 | 0.19 | 5 |
| TOPORS | TOPORS | Q9NS56 | E3 ubiquitin-protein ligase Topors | chr9 | GO:0019787 | Not Cancer Driver | No | 149 | 0.143 | 795 | 105 | 0.132 | 0 |
| TRIM27 | TRIM27 | P14373 | Zinc finger protein RFP | chr6 | GO:0019787 | Census | Yes | 59 | 0.115 | 87 | 11 | 0.126 | 0 |
| TRIM28 | TRIM28 | Q13263 | Transcription intermediary factor 1-beta | chr19 | GO:0019787 | Not Cancer Driver | No | 87 | 0.104 | 430 | 41 | 0.095 | 0 |
| UBA3 | UBA3 | Q8TBC4 | NEDD8-activating enzyme E1 catalytic subunit | chr3 | GO:0019787 | Not Cancer Driver | No | 48 | 0.104 | 44 | 4 | 0.091 | 0 |
| UBE2A | UBE2A | P49459 | Ubiquitin-conjugating enzyme E2 A | chrX | GO:0019787 | Compendium | Yes | 35 | 0.23 | 67 | 13 | 0.194 | 2 |
| UBE2B | UBE2B | P63146 | Ubiquitin-conjugating enzyme E2 B | chr5 | GO:0019787 | Not Cancer Driver | No | 13 | 0.086 | 68 | 6 | 0.088 | 0 |
| UBE2C | UBE2C | O00762 | Ubiquitin-conjugating enzyme E2 C | chr20 | GO:0019787 | Not Cancer Driver | No | 13 | 0.073 | 40 | 0 | 0.0 | 0 |
| UBE2D1 | UBE2D1 | P51668 | Ubiquitin-conjugating enzyme E2 D1 | chr10 | GO:0019787 | Not Cancer Driver | No | 13 | 0.088 | 14 | 0 | 0.0 | 0 |
| UBE2D2 | UBE2D2 | P62837 | Ubiquitin-conjugating enzyme E2 D2 | chr5 | GO:0019787 | Compendium | Yes | 19 | 0.129 | 13 | 1 | 0.077 | 0 |
| UBE2D3_ENST00000394801 | UBE2D3 | P61077 | Ubiquitin-conjugating enzyme E2 D3 | chr4 | GO:0019787 | Not Cancer Driver | No | 21 | 0.143 | 13 | 4 | 0.308 | 0 |
| UBE2D4 | UBE2D4 | Q9Y2X8 | Ubiquitin-conjugating enzyme E2 D4 | chr7 | GO:0019787 | Not Cancer Driver | No | 13 | 0.088 | 21 | 1 | 0.048 | 0 |
| UBE2E1 | UBE2E1 | P51965 | Ubiquitin-conjugating enzyme E2 E1 | chr3 | GO:0019787 | Not Cancer Driver | No | 21 | 0.109 | 78 | 10 | 0.128 | 0 |
| UBE2E2_ENST00000425792 | UBE2E2 | Q96LR5 | Ubiquitin-conjugating enzyme E2 E2 | chr3 | GO:0019787 | Not Cancer Driver | No | 28 | 0.139 | 90 | 15 | 0.167 | 0 |
| UBE2E3_ENST00000602710 | UBE2E3 | Q969T4 | Ubiquitin-conjugating enzyme E2 E3 | chr2 | GO:0019787 | Not Cancer Driver | No | 34 | 0.164 | 97 | 14 | 0.144 | 0 |
| UBE2F_ENST00000272930 | UBE2F | Q969M7 | NEDD8-conjugating enzyme UBE2F | chr2 | GO:0019787 | Not Cancer Driver | No | 21 | 0.114 | 19 | 5 | 0.263 | 0 |
| UBE2G1 | UBE2G1 | P62253 | Ubiquitin-conjugating enzyme E2 G1 | chr17 | GO:0019787 | Not Cancer Driver | No | 9 | 0.053 | 39 | 2 | 0.051 | 0 |
| UBE2G2 | UBE2G2 | P60604 | Ubiquitin-conjugating enzyme E2 G2 | chr21 | GO:0019787 | Not Cancer Driver | No | 24 | 0.145 | 22 | 3 | 0.136 | 0 |
| UBE2H | UBE2H | P62256 | Ubiquitin-conjugating enzyme E2 H | chr7 | GO:0019787 | Not Cancer Driver | No | 20 | 0.109 | 55 | 11 | 0.2 | 0 |
| UBE2I | UBE2I | P63279 | SUMO-conjugating enzyme UBC9 | chr16 | GO:0019787 | Not Cancer Driver | No | 16 | 0.101 | 16 | 3 | 0.188 | 0 |
| UBE2J1 | UBE2J1 | Q9Y385 | Ubiquitin-conjugating enzyme E2 J1 | chr6 | GO:0019787 | Not Cancer Driver | No | 33 | 0.104 | 158 | 20 | 0.127 | 0 |
| UBE2J2_ENST00000349431 | UBE2J2 | Q8N2K1 | Ubiquitin-conjugating enzyme E2 J2 | chr1 | GO:0019787 | Not Cancer Driver | No | 42 | 0.162 | 51 | 7 | 0.137 | 0 |
| UBE2K | UBE2K | P61086 | Ubiquitin-conjugating enzyme E2 K | chr4 | GO:0019787 | Not Cancer Driver | No | 24 | 0.12 | 33 | 3 | 0.091 | 0 |
| UBE2L3_ENST00000342192 | UBE2L3 | P68036 | Ubiquitin-conjugating enzyme E2 L3 | chr22 | GO:0019787 | Not Cancer Driver | No | 19 | 0.123 | 32 | 4 | 0.125 | 0 |
| UBE2L5_ENST00000436446 | UBE2L5 | A0A1B0GUS4 | Ubiquitin-conjugating enzyme E2 L5 | chr13 | GO:0019787 | Not Cancer Driver | No | 1 | 0.006 | 42 | 0 | 0.0 | 0 |
| UBE2L6 | UBE2L6 | O14933 | Ubiquitin/ISG15-conjugating enzyme E2 L6 | chr11 | GO:0019787 | Not Cancer Driver | No | 19 | 0.124 | 7 | 1 | 0.143 | 0 |
| UBE2M | UBE2M | P61081 | NEDD8-conjugating enzyme Ubc12 | chr19 | GO:0019787 | Not Cancer Driver | No | 30 | 0.164 | 32 | 6 | 0.188 | 0 |
| UBE2N | UBE2N | P61088 | Ubiquitin-conjugating enzyme E2 N | chr12 | GO:0019787 | Not Cancer Driver | No | 25 | 0.164 | 24 | 3 | 0.125 | 0 |
| UBE2O | UBE2O | Q9C0C9 | (E3-independent) E2 ubiquitin-conjugating enzyme | chr17 | GO:0019787 | Not Cancer Driver | No | 129 | 0.1 | 716 | 68 | 0.095 | 0 |
| UBE2Q1 | UBE2Q1 | Q7Z7E8 | Ubiquitin-conjugating enzyme E2 Q1 | chr1 | GO:0019787 | Not Cancer Driver | No | 45 | 0.107 | 173 | 16 | 0.092 | 0 |
| UBE2Q2 | UBE2Q2 | Q8WVN8 | Ubiquitin-conjugating enzyme E2 Q2 | chr15 | GO:0019787 | Not Cancer Driver | No | 35 | 0.093 | 122 | 10 | 0.082 | 0 |
| UBE2QL1 | UBE2QL1 | A1L167 | Ubiquitin-conjugating enzyme E2Q-like protein 1 | chr5 | GO:0019787 | Not Cancer Driver | No | 16 | 0.099 | 4 | 0 | 0.0 | 0 |
| UBE2R2 | UBE2R2 | Q712K3 | Ubiquitin-conjugating enzyme E2 R2 | chr9 | GO:0019787 | Not Cancer Driver | No | 28 | 0.118 | 104 | 15 | 0.144 | 0 |
| UBE2S | UBE2S | Q16763 | Ubiquitin-conjugating enzyme E2 S | chr19 | GO:0019787 | Not Cancer Driver | No | 25 | 0.113 | 102 | 12 | 0.118 | 0 |
| UBE2T | UBE2T | Q9NPD8 | Ubiquitin-conjugating enzyme E2 T | chr1 | GO:0019787 | Not Cancer Driver | No | 12 | 0.061 | 97 | 9 | 0.093 | 1 |
| UBE2U_ENST00000611228 | UBE2U | Q5VVX9 | Ubiquitin-conjugating enzyme E2 U | chr1 | GO:0019787 | Not Cancer Driver | No | 38 | 0.118 | 66 | 1 | 0.015 | 0 |
| UBE2W_ENST00000602593 | UBE2W | Q96B02 | Ubiquitin-conjugating enzyme E2 W | chr8 | GO:0019787 | Not Cancer Driver | No | 19 | 0.126 | 26 | 5 | 0.192 | 0 |
| UBE2Z | UBE2Z | Q9H832 | Ubiquitin-conjugating enzyme E2 Z | chr17 | GO:0019787 | Not Cancer Driver | No | 27 | 0.076 | 140 | 10 | 0.071 | 0 |
| UBE4A_ENST00000252108 | UBE4A | Q14139 | Ubiquitin conjugation factor E4 A | chr11 | GO:0019787 | Not Cancer Driver | No | 120 | 0.113 | 121 | 17 | 0.14 | 0 |
| UBE4B | UBE4B | O95155 | Ubiquitin conjugation factor E4 B | chr1 | GO:0019787 | Not Cancer Driver | No | 158 | 0.121 | 434 | 49 | 0.113 | 0 |
| UBL4A | UBL4A | P11441 | Ubiquitin-like protein 4A | chrX | GO:0019787 | Not Cancer Driver | No | 22 | 0.14 | 16 | 5 | 0.312 | 0 |
| UBOX5 | UBOX5 | O94941 | RING finger protein 37 | chr20 | GO:0019787 | Not Cancer Driver | No | 62 | 0.115 | 190 | 24 | 0.126 | 0 |
| UBR5 | UBR5 | O95071 | E3 ubiquitin-protein ligase UBR5 | chr8 | GO:0019787 | Census, Compendium | Yes | 340 | 0.121 | 1296 | 162 | 0.125 | 0 |
| UFC1 | UFC1 | Q9Y3C8 | Ubiquitin-fold modifier-conjugating enzyme 1 | chr1 | GO:0019787 | Not Cancer Driver | No | 24 | 0.144 | 10 | 0 | 0.0 | 2 |
| UFL1 | UFL1 | O94874 | E3 UFM1-protein ligase 1 | chr6 | GO:0019787 | Not Cancer Driver | No | 109 | 0.137 | 141 | 24 | 0.17 | 0 |
| UHRF2 | UHRF2 | Q96PU4 | E3 ubiquitin-protein ligase UHRF2 | chr9 | GO:0019787 | Not Cancer Driver | No | 88 | 0.11 | 253 | 22 | 0.087 | 0 |
| ZBED1 | ZBED1 | O96006 | E3 SUMO-protein ligase ZBED1 | chrX | GO:0019787 | Not Cancer Driver | No | 137 | 0.197 | 97 | 12 | 0.124 | 0 |
| ZNF451 | ZNF451 | Q9Y4E5 | E3 SUMO-protein ligase ZNF451 | chr6 | GO:0019787 | Not Cancer Driver | No | 169 | 0.159 | 191 | 25 | 0.131 | 0 |