Total number of protein in "GO:0019199" GO term: 65
Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ACVR1B_ENST00000257963 | ACVR1B | P36896 | Activin receptor type-1B | chr12 | GO:0019199 | Census | Yes | 114 | 0.226 | 0 | 0 | 0.0 | 0 |
ACVR1C | ACVR1C | Q8NER5 | Activin receptor type-1C | chr2 | GO:0019199 | Not Cancer Driver | No | 90 | 0.183 | 3 | 1 | 0.333 | 0 |
ACVR1_ENST00000434821 | ACVR1 | Q04771 | Activin receptor type-1 | chr2 | GO:0019199 | Census, Compendium | Yes | 78 | 0.153 | 21 | 8 | 0.381 | 8 |
ACVR2A_ENST00000404590 | ACVR2A | P27037 | Activin receptor type-2A | chr2 | GO:0019199 | Census, Compendium | Yes | 98 | 0.191 | 56 | 6 | 0.107 | 0 |
ACVR2B | ACVR2B | Q13705 | Activin receptor type-2B | chr3 | GO:0019199 | Not Cancer Driver | No | 83 | 0.162 | 70 | 14 | 0.2 | 2 |
ACVRL1 | ACVRL1 | P37023 | Serine/threonine-protein kinase receptor R3 | chr12 | GO:0019199 | Not Cancer Driver | No | 93 | 0.185 | 60 | 11 | 0.183 | 82 |
AMHR2 | AMHR2 | Q16671 | Anti-Muellerian hormone type-2 receptor | chr12 | GO:0019199 | Not Cancer Driver | No | 77 | 0.134 | 117 | 7 | 0.06 | 8 |
BMPR1A | BMPR1A | P36894 | Bone morphogenetic protein receptor type-1A | chr10 | GO:0019199 | Census, Compendium | Yes | 66 | 0.124 | 21 | 0 | 0.0 | 8 |
BMPR1B_ENST00000394931 | BMPR1B | O00238 | Bone morphogenetic protein receptor type-1B | chr4 | GO:0019199 | Not Cancer Driver | No | 84 | 0.167 | 64 | 12 | 0.188 | 5 |
BMPR2 | BMPR2 | Q13873 | Bone morphogenetic protein receptor type-2 | chr2 | GO:0019199 | Compendium | Yes | 141 | 0.136 | 601 | 70 | 0.116 | 19 |
CRIM1 | CRIM1 | Q9NZV1 | Cysteine-rich motor neuron 1 protein | chr2 | GO:0019199 | Not Cancer Driver | No | 133 | 0.128 | 35 | 4 | 0.114 | 0 |
CSF1R | CSF1R | P07333 | Macrophage colony-stimulating factor 1 receptor | chr5 | GO:0019199 | Census | Yes | 133 | 0.137 | 124 | 17 | 0.137 | 20 |
DDR1_ENST00000324771 | DDR1 | Q08345 | Epithelial discoidin domain-containing receptor 1 | chr6 | GO:0019199 | Not Cancer Driver | No | 123 | 0.135 | 253 | 49 | 0.194 | 0 |
DDR2 | DDR2 | Q16832 | Discoidin domain-containing receptor 2 | chr1 | GO:0019199 | Census | Yes | 192 | 0.225 | 118 | 34 | 0.288 | 7 |
EFEMP1_ENST00000355426 | EFEMP1 | Q12805 | EGF-containing fibulin-like extracellular matrix protein 1 | chr2 | GO:0019199 | Not Cancer Driver | No | 95 | 0.193 | 73 | 21 | 0.288 | 1 |
EFNA3 | EFNA3 | P52797 | Ephrin-A3 | chr1 | GO:0019199 | Not Cancer Driver | No | 24 | 0.101 | 31 | 11 | 0.355 | 0 |
EFNA4_ENST00000368409 | EFNA4 | P52798 | Ephrin-A4 | chr1 | GO:0019199 | Not Cancer Driver | No | 28 | 0.139 | 17 | 3 | 0.176 | 0 |
EFNB3 | EFNB3 | Q15768 | Ephrin-B3 | chr17 | GO:0019199 | Not Cancer Driver | No | 45 | 0.132 | 183 | 22 | 0.12 | 0 |
EGFR | EGFR | P00533 | Epidermal growth factor receptor | chr7 | GO:0019199 | Census, Compendium | Yes | 444 | 0.367 | 223 | 35 | 0.157 | 1 |
ENG | ENG | P17813 | Endoglin | chr9 | GO:0019199 | Not Cancer Driver | No | 60 | 0.091 | 114 | 15 | 0.132 | 32 |
EPHA1 | EPHA1 | P21709 | Ephrin type-A receptor 1 | chr7 | GO:0019199 | Not Cancer Driver | No | 147 | 0.151 | 211 | 38 | 0.18 | 0 |
EPHA10 | EPHA10 | Q5JZY3 | Ephrin type-A receptor 10 | chr1 | GO:0019199 | Not Cancer Driver | No | 171 | 0.17 | 225 | 41 | 0.182 | 0 |
EPHA2 | EPHA2 | P29317 | Ephrin type-A receptor 2 | chr1 | GO:0019199 | Compendium | Yes | 171 | 0.175 | 187 | 39 | 0.209 | 3 |
EPHA3 | EPHA3 | P29320 | Ephrin type-A receptor 3 | chr3 | GO:0019199 | Census, Compendium | Yes | 346 | 0.352 | 74 | 28 | 0.378 | 0 |
EPHA4_ENST00000409938 | EPHA4 | P54764 | Ephrin type-A receptor 4 | chr2 | GO:0019199 | Not Cancer Driver | No | 182 | 0.185 | 140 | 24 | 0.171 | 0 |
EPHA5_ENST00000273854 | EPHA5 | P54756 | Ephrin type-A receptor 5 | chr4 | GO:0019199 | Not Cancer Driver | No | 341 | 0.329 | 83 | 39 | 0.47 | 0 |
EPHA7 | EPHA7 | Q15375 | Ephrin type-A receptor 7 | chr6 | GO:0019199 | Census, Compendium | Yes | 280 | 0.281 | 71 | 15 | 0.211 | 0 |
EPHA8 | EPHA8 | P29322 | Ephrin type-A receptor 8 | chr1 | GO:0019199 | Not Cancer Driver | No | 197 | 0.196 | 121 | 17 | 0.14 | 0 |
EPHB1 | EPHB1 | P54762 | Ephrin type-B receptor 1 | chr3 | GO:0019199 | Not Cancer Driver | No | 316 | 0.321 | 67 | 17 | 0.254 | 0 |
EPHB2 | EPHB2 | P29323 | Ephrin type-B receptor 2 | chr1 | GO:0019199 | Not Cancer Driver | No | 186 | 0.176 | 119 | 17 | 0.143 | 7 |
EPHB3 | EPHB3 | P54753 | Ephrin type-B receptor 3 | chr3 | GO:0019199 | Not Cancer Driver | No | 155 | 0.155 | 137 | 16 | 0.117 | 0 |
EPHB4 | EPHB4 | P54760 | Ephrin type-B receptor 4 | chr7 | GO:0019199 | Not Cancer Driver | No | 125 | 0.127 | 184 | 19 | 0.103 | 11 |
EPHB6_ENST00000422643 | EPHB6 | O15197 | Ephrin type-B receptor 6 | chr7 | GO:0019199 | Not Cancer Driver | No | 227 | 0.222 | 246 | 45 | 0.183 | 0 |
FGFR1_ENST00000447712 | FGFR1 | P11362 | Fibroblast growth factor receptor 1 | chr8 | GO:0019199 | Census, Compendium | Yes | 152 | 0.185 | 230 | 43 | 0.187 | 74 |
FGFR2_ENST00000358487 | FGFR2 | P21802 | Fibroblast growth factor receptor 2 | chr10 | GO:0019199 | Census, Compendium | Yes | 238 | 0.29 | 228 | 44 | 0.193 | 72 |
FGFR3_ENST00000440486 | FGFR3 | P22607 | Fibroblast growth factor receptor 3 | chr4 | GO:0019199 | Census, Compendium | Yes | 173 | 0.215 | 241 | 26 | 0.108 | 37 |
FGFR4 | FGFR4 | P22455 | Fibroblast growth factor receptor 4 | chr5 | GO:0019199 | Census, Compendium | Yes | 113 | 0.141 | 162 | 28 | 0.173 | 0 |
FGFRL1_ENST00000264748 | FGFRL1 | Q8N441 | Fibroblast growth factor receptor-like 1 | chr4 | GO:0019199 | Not Cancer Driver | No | 74 | 0.147 | 278 | 34 | 0.122 | 0 |
FLT1 | FLT1 | P17948 | Vascular endothelial growth factor receptor 1 | chr13 | GO:0019199 | Not Cancer Driver | No | 299 | 0.223 | 103 | 20 | 0.194 | 0 |
FLT3 | FLT3 | P36888 | Receptor-type tyrosine-protein kinase FLT3 | chr13 | GO:0019199 | Census, Compendium | Yes | 200 | 0.201 | 64 | 27 | 0.422 | 0 |
FLT4 | FLT4 | P35916 | Vascular endothelial growth factor receptor 3 | chr5 | GO:0019199 | Census, Compendium | Yes | 253 | 0.186 | 259 | 41 | 0.158 | 13 |
HJV | HJV | Q6ZVN8 | Hemojuvelin | chr1 | GO:0019199 | Not Cancer Driver | No | 75 | 0.176 | 117 | 27 | 0.231 | 14 |
IGF1R | IGF1R | P08069 | Insulin-like growth factor 1 receptor | chr15 | GO:0019199 | Not Cancer Driver | No | 183 | 0.134 | 265 | 37 | 0.14 | 6 |
IGF2R | IGF2R | P11717 | Cation-independent mannose-6-phosphate receptor | chr6 | GO:0019199 | Not Cancer Driver | No | 318 | 0.128 | 255 | 20 | 0.078 | 0 |
INSR | INSR | P06213 | Insulin receptor | chr19 | GO:0019199 | Not Cancer Driver | No | 190 | 0.137 | 280 | 57 | 0.204 | 64 |
INSRR | INSRR | P14616 | Insulin receptor-related protein | chr1 | GO:0019199 | Not Cancer Driver | No | 262 | 0.202 | 228 | 37 | 0.162 | 0 |
KDR | KDR | P35968 | Vascular endothelial growth factor receptor 2 | chr4 | GO:0019199 | Census, Compendium | Yes | 357 | 0.263 | 275 | 55 | 0.2 | 2 |
KIT | KIT | P10721 | Mast/stem cell growth factor receptor Kit | chr4 | GO:0019199 | Census, Compendium | Yes | 226 | 0.232 | 83 | 33 | 0.398 | 21 |
LTBP1 | LTBP1 | Q14766 | Latent-transforming growth factor beta-binding protein 1 | chr2 | GO:0019199 | Not Cancer Driver | No | 300 | 0.174 | 518 | 78 | 0.151 | 0 |
LTBP4 | LTBP4 | Q8N2S1 | Latent-transforming growth factor beta-binding protein 4 | chr19 | GO:0019199 | Not Cancer Driver | No | 191 | 0.118 | 432 | 42 | 0.097 | 1 |
MET_ENST00000397752 | MET | P08581 | Hepatocyte growth factor receptor | chr7 | GO:0019199 | Census, Compendium | Yes | 226 | 0.163 | 62 | 15 | 0.242 | 19 |
MST1R | MST1R | Q04912 | Macrophage-stimulating protein receptor | chr3 | GO:0019199 | Not Cancer Driver | No | 178 | 0.127 | 182 | 27 | 0.148 | 1 |
MUSK | MUSK | O15146 | Muscle, skeletal receptor tyrosine-protein kinase | chr9 | GO:0019199 | Not Cancer Driver | No | 188 | 0.216 | 35 | 7 | 0.2 | 7 |
NRP1 | NRP1 | O14786 | Neuropilin-1 | chr10 | GO:0019199 | Compendium | Yes | 146 | 0.158 | 211 | 31 | 0.147 | 0 |
NRP2 | NRP2 | O60462 | Neuropilin-2 | chr2 | GO:0019199 | Not Cancer Driver | No | 161 | 0.173 | 207 | 45 | 0.217 | 0 |
NTRK1 | NTRK1 | P04629 | High affinity nerve growth factor receptor | chr1 | GO:0019199 | Census, Compendium | Yes | 168 | 0.211 | 57 | 8 | 0.14 | 25 |
NTRK2_ENST00000323115 | NTRK2 | Q16620 | BDNF/NT-3 growth factors receptor | chr9 | GO:0019199 | Not Cancer Driver | No | 155 | 0.189 | 117 | 18 | 0.154 | 1 |
NTRK3_ENST00000629765 | NTRK3 | Q16288 | NT-3 growth factor receptor | chr15 | GO:0019199 | Census, Compendium | Yes | 249 | 0.297 | 57 | 21 | 0.368 | 0 |
PDGFRA | PDGFRA | P16234 | Platelet-derived growth factor receptor alpha | chr4 | GO:0019199 | Census, Compendium | Yes | 290 | 0.266 | 173 | 45 | 0.26 | 2 |
PDGFRB | PDGFRB | P09619 | Platelet-derived growth factor receptor beta | chr5 | GO:0019199 | Census, Compendium | Yes | 164 | 0.148 | 231 | 44 | 0.19 | 7 |
PDGFRL | PDGFRL | Q15198 | Platelet-derived growth factor receptor-like protein | chr8 | GO:0019199 | Not Cancer Driver | No | 46 | 0.123 | 67 | 12 | 0.179 | 1 |
SOSTDC1 | SOSTDC1 | Q6X4U4 | Sclerostin domain-containing protein 1 | chr7 | GO:0019199 | Not Cancer Driver | No | 22 | 0.107 | 72 | 3 | 0.042 | 0 |
TGFBR1_ENST00000374994 | TGFBR1 | P36897 | TGF-beta receptor type-1 | chr9 | GO:0019199 | Not Cancer Driver | No | 86 | 0.171 | 23 | 3 | 0.13 | 15 |
TGFBR2_ENST00000295754 | TGFBR2 | P37173 | TGF-beta receptor type-2 | chr3 | GO:0019199 | Census, Compendium | Yes | 106 | 0.187 | 60 | 16 | 0.267 | 25 |
TGFBR3_ENST00000525962 | TGFBR3 | Q03167 | Transforming growth factor beta receptor type 3 | chr1 | GO:0019199 | Not Cancer Driver | No | 129 | 0.152 | 268 | 41 | 0.153 | 0 |