Total number of protein in "GO:0017022" GO term: 70
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACTA1 | ACTA1 | P68133 | Actin, alpha skeletal muscle | chr1 | GO:0017022 | Not Cancer Driver | No | 70 | 0.186 | 48 | 14 | 0.292 | 84 |
| ACTC1 | ACTC1 | P68032 | Actin, alpha cardiac muscle 1 | chr15 | GO:0017022 | Not Cancer Driver | No | 114 | 0.302 | 48 | 19 | 0.396 | 11 |
| ARFGEF1 | ARFGEF1 | Q9Y6D6 | Brefeldin A-inhibited guanine nucleotide-exchange protein 1 | chr8 | GO:0017022 | Not Cancer Driver | No | 243 | 0.131 | 456 | 54 | 0.118 | 0 |
| ARFGEF2 | ARFGEF2 | Q9Y6D5 | Brefeldin A-inhibited guanine nucleotide-exchange protein 2 | chr20 | GO:0017022 | Not Cancer Driver | No | 254 | 0.142 | 358 | 63 | 0.176 | 0 |
| AXL | AXL | P30530 | Tyrosine-protein kinase receptor UFO | chr19 | GO:0017022 | Not Cancer Driver | No | 168 | 0.188 | 341 | 64 | 0.188 | 0 |
| CALD1 | CALD1 | Q05682 | Caldesmon | chr7 | GO:0017022 | Not Cancer Driver | No | 133 | 0.168 | 793 | 133 | 0.168 | 0 |
| CORO1A | CORO1A | P31146 | Coronin-1A | chr16 | GO:0017022 | Not Cancer Driver | No | 51 | 0.111 | 126 | 15 | 0.119 | 1 |
| CXCR4_ENST00000241393 | CXCR4 | P61073 | C-X-C chemokine receptor type 4 | chr2 | GO:0017022 | Census, Compendium | Yes | 62 | 0.176 | 5 | 1 | 0.2 | 0 |
| DMD | DMD | P11532 | Dystrophin | chrX | GO:0017022 | Not Cancer Driver | No | 895 | 0.243 | 1399 | 329 | 0.235 | 14 |
| GCSAM_ENST00000308910 | GCSAM | Q8N6F7 | Germinal center-associated signaling and motility protein | chr3 | GO:0017022 | Not Cancer Driver | No | 31 | 0.174 | 136 | 22 | 0.162 | 0 |
| GIPC1 | GIPC1 | O14908 | PDZ domain-containing protein GIPC1 | chr19 | GO:0017022 | Not Cancer Driver | No | 47 | 0.141 | 138 | 17 | 0.123 | 0 |
| GSN | GSN | P06396 | Gelsolin | chr9 | GO:0017022 | Not Cancer Driver | No | 76 | 0.097 | 316 | 28 | 0.089 | 2 |
| HAP1_ENST00000310778 | HAP1 | P54257 | Huntingtin-associated protein 1 | chr17 | GO:0017022 | Not Cancer Driver | No | 97 | 0.145 | 454 | 60 | 0.132 | 0 |
| IQGAP3 | IQGAP3 | Q86VI3 | Ras GTPase-activating-like protein IQGAP3 | chr1 | GO:0017022 | Not Cancer Driver | No | 233 | 0.143 | 257 | 36 | 0.14 | 0 |
| KIRREL1 | KIRREL1 | Q96J84 | Kin of IRRE-like protein 1 | chr1 | GO:0017022 | Not Cancer Driver | No | 141 | 0.186 | 273 | 57 | 0.209 | 1 |
| LARP6 | LARP6 | Q9BRS8 | La-related protein 6 | chr15 | GO:0017022 | Not Cancer Driver | No | 64 | 0.13 | 329 | 48 | 0.146 | 0 |
| LIMCH1_ENST00000313860 | LIMCH1 | Q9UPQ0 | LIM and calponin homology domains-containing protein 1 | chr4 | GO:0017022 | Not Cancer Driver | No | 177 | 0.163 | 880 | 140 | 0.159 | 0 |
| LLGL1 | LLGL1 | Q15334 | Lethal(2) giant larvae protein homolog 1 | chr17 | GO:0017022 | Not Cancer Driver | No | 101 | 0.095 | 265 | 12 | 0.045 | 0 |
| LLGL2 | LLGL2 | Q6P1M3 | LLGL scribble cell polarity complex component 2 | chr17 | GO:0017022 | Not Cancer Driver | No | 120 | 0.118 | 266 | 26 | 0.098 | 0 |
| LMTK2 | LMTK2 | Q8IWU2 | Serine/threonine-protein kinase LMTK2 | chr7 | GO:0017022 | Not Cancer Driver | No | 211 | 0.14 | 1018 | 141 | 0.139 | 0 |
| MLPH | MLPH | Q9BV36 | Melanophilin | chr2 | GO:0017022 | Not Cancer Driver | No | 78 | 0.13 | 463 | 57 | 0.123 | 1 |
| MOBP_ENST00000441980 | MOBP | Q13875 | Myelin-associated oligodendrocyte basic protein | chr3 | GO:0017022 | Not Cancer Driver | No | 15 | 0.082 | 137 | 8 | 0.058 | 0 |
| MYBPC1_ENST00000550270 | MYBPC1 | Q00872 | Myosin-binding protein C, slow-type | chr12 | GO:0017022 | Not Cancer Driver | No | 227 | 0.199 | 220 | 38 | 0.173 | 7 |
| MYBPC3 | MYBPC3 | Q14896 | Myosin-binding protein C, cardiac-type | chr11 | GO:0017022 | Not Cancer Driver | No | 178 | 0.14 | 434 | 62 | 0.143 | 64 |
| MYH8 | MYH8 | P13535 | Myosin-8 | chr17 | GO:0017022 | Not Cancer Driver | No | 498 | 0.257 | 1086 | 315 | 0.29 | 2 |
| MYL12A_ENST00000217652 | MYL12A | P19105 | Myosin regulatory light chain 12A | chr18 | GO:0017022 | Not Cancer Driver | No | 19 | 0.111 | 70 | 13 | 0.186 | 0 |
| MYL12B_ENST00000237500 | MYL12B | O14950 | Myosin regulatory light chain 12B | chr18 | GO:0017022 | Not Cancer Driver | No | 23 | 0.134 | 61 | 13 | 0.213 | 0 |
| MYL2 | MYL2 | P10916 | Myosin regulatory light chain 2, ventricular/cardiac muscle isoform | chr12 | GO:0017022 | Not Cancer Driver | No | 44 | 0.265 | 34 | 8 | 0.235 | 6 |
| MYL3 | MYL3 | P08590 | Myosin light chain 3 | chr3 | GO:0017022 | Not Cancer Driver | No | 21 | 0.108 | 99 | 9 | 0.091 | 5 |
| MYL4_ENST00000572316 | MYL4 | P12829 | Myosin light chain 4 | chr17 | GO:0017022 | Not Cancer Driver | No | 29 | 0.147 | 104 | 11 | 0.106 | 1 |
| MYL9 | MYL9 | P24844 | Myosin regulatory light polypeptide 9 | chr20 | GO:0017022 | Not Cancer Driver | No | 34 | 0.198 | 82 | 19 | 0.232 | 0 |
| MYLK2 | MYLK2 | Q9H1R3 | Myosin light chain kinase 2, skeletal/cardiac muscle | chr20 | GO:0017022 | Not Cancer Driver | No | 118 | 0.198 | 277 | 64 | 0.231 | 2 |
| MYOC | MYOC | Q99972 | Myocilin | chr1 | GO:0017022 | Not Cancer Driver | No | 92 | 0.183 | 196 | 43 | 0.219 | 58 |
| MYRIP | MYRIP | Q8NFW9 | Rab effector MyRIP | chr3 | GO:0017022 | Not Cancer Driver | No | 133 | 0.155 | 599 | 95 | 0.159 | 0 |
| NKD2 | NKD2 | Q969F2 | Protein naked cuticle homolog 2 | chr5 | GO:0017022 | Not Cancer Driver | No | 64 | 0.142 | 451 | 64 | 0.142 | 0 |
| NPC1L1 | NPC1L1 | Q9UHC9 | NPC1-like intracellular cholesterol transporter 1 | chr7 | GO:0017022 | Not Cancer Driver | No | 222 | 0.163 | 8 | 2 | 0.25 | 0 |
| NPHS1 | NPHS1 | O60500 | Nephrin | chr19 | GO:0017022 | Not Cancer Driver | No | 230 | 0.185 | 484 | 108 | 0.223 | 62 |
| PYCARD | PYCARD | Q9ULZ3 | Apoptosis-associated speck-like protein containing a CARD | chr16 | GO:0017022 | Not Cancer Driver | No | 16 | 0.082 | 39 | 4 | 0.103 | 0 |
| RAB10 | RAB10 | P61026 | Ras-related protein Rab-10 | chr2 | GO:0017022 | Not Cancer Driver | No | 19 | 0.095 | 28 | 2 | 0.071 | 0 |
| RAB11A | RAB11A | P62491 | Ras-related protein Rab-11A | chr15 | GO:0017022 | Not Cancer Driver | No | 31 | 0.144 | 43 | 4 | 0.093 | 0 |
| RAB11B | RAB11B | Q15907 | Ras-related protein Rab-11B | chr19 | GO:0017022 | Not Cancer Driver | No | 26 | 0.119 | 39 | 3 | 0.077 | 2 |
| RAB14 | RAB14 | P61106 | Ras-related protein Rab-14 | chr9 | GO:0017022 | Not Cancer Driver | No | 20 | 0.093 | 41 | 4 | 0.098 | 0 |
| RAB25 | RAB25 | P57735 | Ras-related protein Rab-25 | chr1 | GO:0017022 | Not Cancer Driver | No | 26 | 0.122 | 32 | 5 | 0.156 | 0 |
| RAB27A_ENST00000336787 | RAB27A | P51159 | Ras-related protein Rab-27A | chr15 | GO:0017022 | Not Cancer Driver | No | 25 | 0.113 | 15 | 4 | 0.267 | 3 |
| RAB27B | RAB27B | O00194 | Ras-related protein Rab-27B | chr18 | GO:0017022 | Not Cancer Driver | No | 42 | 0.193 | 43 | 9 | 0.209 | 0 |
| RAB39B | RAB39B | Q96DA2 | Ras-related protein Rab-39B | chrX | GO:0017022 | Not Cancer Driver | No | 45 | 0.211 | 0 | 0 | 0.0 | 2 |
| RAB3A | RAB3A | P20336 | Ras-related protein Rab-3A | chr19 | GO:0017022 | Not Cancer Driver | No | 25 | 0.114 | 43 | 4 | 0.093 | 0 |
| RAB3B | RAB3B | P20337 | Ras-related protein Rab-3B | chr1 | GO:0017022 | Not Cancer Driver | No | 36 | 0.164 | 25 | 6 | 0.24 | 0 |
| RAB3C | RAB3C | Q96E17 | Ras-related protein Rab-3C | chr5 | GO:0017022 | Not Cancer Driver | No | 52 | 0.229 | 54 | 10 | 0.185 | 0 |
| RAB3D_ENST00000589655 | RAB3D | O95716 | Ras-related protein Rab-3D | chr19 | GO:0017022 | Not Cancer Driver | No | 37 | 0.169 | 46 | 6 | 0.13 | 0 |
| RAB6A_ENST00000336083 | RAB6A | P20340 | Ras-related protein Rab-6A | chr11 | GO:0017022 | Not Cancer Driver | No | 22 | 0.106 | 45 | 6 | 0.133 | 0 |
| RAB6B | RAB6B | Q9NRW1 | Ras-related protein Rab-6B | chr3 | GO:0017022 | Not Cancer Driver | No | 39 | 0.188 | 42 | 5 | 0.119 | 0 |
| RAB8A | RAB8A | P61006 | Ras-related protein Rab-8A | chr19 | GO:0017022 | Not Cancer Driver | No | 37 | 0.179 | 26 | 3 | 0.115 | 0 |
| RALA | RALA | P11233 | Ras-related protein Ral-A | chr7 | GO:0017022 | Not Cancer Driver | No | 34 | 0.165 | 34 | 3 | 0.088 | 5 |
| RHOA | RHOA | P61586 | Transforming protein RhoA | chr3 | GO:0017022 | Census, Compendium | Yes | 99 | 0.513 | 46 | 13 | 0.283 | 2 |
| SHROOM1 | SHROOM1 | Q2M3G4 | Protein Shroom1 | chr5 | GO:0017022 | Not Cancer Driver | No | 70 | 0.082 | 712 | 57 | 0.08 | 0 |
| SHROOM4 | SHROOM4 | Q9ULL8 | Protein Shroom4 | chrX | GO:0017022 | Not Cancer Driver | No | 242 | 0.162 | 1027 | 167 | 0.163 | 1 |
| SLC9A3R1 | SLC9A3R1 | O14745 | Na(+)/H(+) exchange regulatory cofactor NHE-RF1 | chr17 | GO:0017022 | Not Cancer Driver | No | 19 | 0.053 | 318 | 16 | 0.05 | 4 |
| SPATA6 | SPATA6 | Q9NWH7 | Spermatogenesis-associated protein 6 | chr1 | GO:0017022 | Not Cancer Driver | No | 63 | 0.129 | 278 | 38 | 0.137 | 0 |
| SPTBN5 | SPTBN5 | Q9NRC6 | Spectrin beta chain, non-erythrocytic 5 | chr15 | GO:0017022 | Not Cancer Driver | No | 314 | 0.085 | 1274 | 118 | 0.093 | 0 |
| STX1A | STX1A | Q16623 | Syntaxin-1A | chr7 | GO:0017022 | Not Cancer Driver | No | 35 | 0.122 | 136 | 11 | 0.081 | 0 |
| STXBP5 | STXBP5 | Q5T5C0 | Syntaxin-binding protein 5 | chr6 | GO:0017022 | Not Cancer Driver | No | 128 | 0.111 | 344 | 46 | 0.134 | 0 |
| STXBP5L | STXBP5L | Q9Y2K9 | Syntaxin-binding protein 5-like | chr3 | GO:0017022 | Not Cancer Driver | No | 358 | 0.302 | 292 | 101 | 0.346 | 0 |
| TRAK1 | TRAK1 | Q9UPV9 | Trafficking kinesin-binding protein 1 | chr3 | GO:0017022 | Not Cancer Driver | No | 118 | 0.124 | 619 | 74 | 0.12 | 0 |
| TRAK2 | TRAK2 | O60296 | Trafficking kinesin-binding protein 2 | chr2 | GO:0017022 | Not Cancer Driver | No | 112 | 0.123 | 576 | 70 | 0.122 | 0 |
| TRIM32 | TRIM32 | Q13049 | E3 ubiquitin-protein ligase TRIM32 | chr9 | GO:0017022 | Not Cancer Driver | No | 82 | 0.126 | 87 | 10 | 0.115 | 3 |
| TRIOBP_ENST00000644935 | TRIOBP | Q9H2D6 | TRIO and F-actin-binding protein | chr22 | GO:0017022 | Not Cancer Driver | No | 386 | 0.163 | 2196 | 370 | 0.168 | 1 |
| TRPM7 | TRPM7 | Q96QT4 | Transient receptor potential cation channel subfamily M member 7 | chr15 | GO:0017022 | Not Cancer Driver | No | 199 | 0.107 | 455 | 60 | 0.132 | 0 |
| USH2A | USH2A | O75445 | Usherin | chr1 | GO:0017022 | Not Cancer Driver | No | 1503 | 0.289 | 773 | 235 | 0.304 | 70 |
| VEZT | VEZT | Q9HBM0 | Vezatin | chr12 | GO:0017022 | Not Cancer Driver | No | 83 | 0.107 | 278 | 22 | 0.079 | 0 |