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Total number of protein in "GO:0017015" GO term:  58

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ADAM17 ADAM17 P78536 Disintegrin and metalloproteinase domain-containing protein 17 chr2 GO:0017015 Not Cancer Driver No 80 0.097 182 17 0.093 0
AXIN1 AXIN1 O15169 Axin-1 chr16 GO:0017015 Census, Compendium Yes 120 0.139 619 88 0.142 4
BCL9 BCL9 O00512 B-cell CLL/lymphoma 9 protein chr1 GO:0017015 Census, Compendium Yes 219 0.154 1426 219 0.154 0
C20orf27_ENST00000379772 C20orf27 Q9GZN8 UPF0687 protein C20orf27 chr20 GO:0017015 Not Cancer Driver No 27 0.155 31 4 0.129 0
CAV3 CAV3 P56539 Caveolin-3 chr3 GO:0017015 Not Cancer Driver No 27 0.179 0 0 0.0 25
CDKN1C CDKN1C P49918 Cyclin-dependent kinase inhibitor 1C chr11 GO:0017015 Not Cancer Driver No 2 0.006 256 1 0.004 7
CDKN2B CDKN2B P42772 Cyclin-dependent kinase 4 inhibitor B chr9 GO:0017015 Not Cancer Driver No 15 0.109 67 3 0.045 0
CITED1_ENST00000246139 CITED1 Q99966 Cbp/p300-interacting transactivator 1 chrX GO:0017015 Not Cancer Driver No 24 0.124 166 21 0.127 0
CITED2_ENST00000367651 CITED2 Q99967 Cbp/p300-interacting transactivator 2 chr6 GO:0017015 Not Cancer Driver No 23 0.085 230 18 0.078 0
CREBBP CREBBP Q92793 CREB-binding protein chr16 GO:0017015 Census, Compendium Yes 412 0.169 1796 247 0.138 33
DAB2 DAB2 P98082 Disabled homolog 2 chr5 GO:0017015 Not Cancer Driver No 144 0.187 680 125 0.184 0
DKK3_ENST00000326932 DKK3 Q9UBP4 Dickkopf-related protein 3 chr11 GO:0017015 Not Cancer Driver No 44 0.126 161 22 0.137 0
EID2 EID2 Q8N6I1 EP300-interacting inhibitor of differentiation 2 chr19 GO:0017015 Not Cancer Driver No 18 0.076 136 8 0.059 0
ENG ENG P17813 Endoglin chr9 GO:0017015 Not Cancer Driver No 60 0.091 114 15 0.132 32
EP300 EP300 Q09472 Histone acetyltransferase p300 chr22 GO:0017015 Census, Compendium Yes 334 0.138 1790 196 0.109 1
FBN1 FBN1 P35555 Fibrillin-1 chr15 GO:0017015 Not Cancer Driver No 466 0.162 110 16 0.145 360
FBN2_ENST00000262464 FBN2 P35556 Fibrillin-2 chr5 GO:0017015 Compendium Yes 607 0.208 135 24 0.178 30
FERMT1 FERMT1 Q9BQL6 Fermitin family homolog 1 chr20 GO:0017015 Not Cancer Driver No 100 0.148 65 8 0.123 2
FLCN FLCN Q8NFG4 Folliculin chr17 GO:0017015 Census, Compendium Yes 59 0.102 157 19 0.121 5
FOLR1_ENST00000393681 FOLR1 P15328 Folate receptor alpha chr11 GO:0017015 Not Cancer Driver No 41 0.16 13 3 0.231 0
GIPC1 GIPC1 O14908 PDZ domain-containing protein GIPC1 chr19 GO:0017015 Not Cancer Driver No 47 0.141 138 17 0.123 0
HIPK2 HIPK2 Q9H2X6 Homeodomain-interacting protein kinase 2 chr7 GO:0017015 Not Cancer Driver No 154 0.129 686 96 0.14 0
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 GO:0017015 Census, Compendium Yes 100 0.138 254 43 0.169 0
IL17F IL17F Q96PD4 Interleukin-17F chr6 GO:0017015 Not Cancer Driver No 42 0.258 34 11 0.324 1
ING2 ING2 Q9H160 Inhibitor of growth protein 2 chr4 GO:0017015 Not Cancer Driver No 33 0.118 169 26 0.154 0
ITGA3 ITGA3 P26006 Integrin alpha-3 chr17 GO:0017015 Not Cancer Driver No 106 0.101 129 18 0.14 3
ITGA8 ITGA8 P53708 Integrin alpha-8 chr10 GO:0017015 Not Cancer Driver No 292 0.275 114 26 0.228 1
LATS1 LATS1 O95835 Serine/threonine-protein kinase LATS1 chr6 GO:0017015 Census, Compendium Yes 161 0.142 788 100 0.127 0
LATS2 LATS2 Q9NRM7 Serine/threonine-protein kinase LATS2 chr13 GO:0017015 Census, Compendium Yes 178 0.164 687 116 0.169 0
LOX LOX P28300 Protein-lysine 6-oxidase chr5 GO:0017015 Compendium Yes 44 0.106 172 11 0.064 4
LRG1 LRG1 P02750 Leucine-rich alpha-2-glycoprotein chr19 GO:0017015 Not Cancer Driver No 63 0.182 29 8 0.276 0
LTBP1 LTBP1 Q14766 Latent-transforming growth factor beta-binding protein 1 chr2 GO:0017015 Not Cancer Driver No 300 0.174 518 78 0.151 0
LTBP4 LTBP4 Q8N2S1 Latent-transforming growth factor beta-binding protein 4 chr19 GO:0017015 Not Cancer Driver No 191 0.118 432 42 0.097 1
MEN1 MEN1 O00255 Menin chr11 GO:0017015 Census, Compendium Yes 73 0.119 228 15 0.066 90
MPP5 PALS1 Q8N3R9 Protein PALS1 chr14 GO:0017015 Not Cancer Driver No 70 0.104 337 33 0.098 0
MYOCD_ENST00000343344 MYOCD Q8IZQ8 Myocardin chr17 GO:0017015 Not Cancer Driver No 284 0.303 853 263 0.308 0
NPNT_ENST00000379987 NPNT Q6UXI9 Nephronectin chr4 GO:0017015 Not Cancer Driver No 90 0.159 218 33 0.151 0
NREP_ENST00000447165 NREP Q16612 Neuronal regeneration-related protein chr5 GO:0017015 Not Cancer Driver No 17 0.25 36 13 0.361 0
NRROS NRROS Q86YC3 Transforming growth factor beta activator LRRC33 chr3 GO:0017015 Not Cancer Driver No 109 0.158 8 1 0.125 0
RNF111_ENST00000557998 RNF111 Q6ZNA4 E3 ubiquitin-protein ligase Arkadia chr15 GO:0017015 Not Cancer Driver No 111 0.112 855 96 0.112 0
SDCBP_ENST00000260130 SDCBP O00560 Syntenin-1 chr8 GO:0017015 Not Cancer Driver No 39 0.131 17 2 0.118 0
SLC2A10 SLC2A10 O95528 Solute carrier family 2, facilitated glucose transporter member 10 chr20 GO:0017015 Not Cancer Driver No 98 0.181 72 15 0.208 8
SMAD2_ENST00000402690 SMAD2 Q15796 Mothers against decapentaplegic homolog 2 chr18 GO:0017015 Census, Compendium Yes 79 0.169 137 12 0.088 0
SMAD3 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 GO:0017015 Census, Compendium Yes 97 0.228 111 19 0.171 5
SMAD4_ENST00000398417 SMAD4 Q13485 Mothers against decapentaplegic homolog 4 chr18 GO:0017015 Census, Compendium Yes 198 0.359 195 17 0.087 8
SMAD7 SMAD7 O15105 Mothers against decapentaplegic homolog 7 chr18 GO:0017015 Not Cancer Driver No 40 0.094 139 0 0.0 0
SMURF2 SMURF2 Q9HAU4 E3 ubiquitin-protein ligase SMURF2 chr17 GO:0017015 Not Cancer Driver No 87 0.116 242 28 0.116 0
SNW1_ENST00000261531 SNW1 Q13573 SNW domain-containing protein 1 chr14 GO:0017015 Not Cancer Driver No 62 0.116 488 56 0.115 0
SOX11 SOX11 P35716 Transcription factor SOX-11 chr2 GO:0017015 Not Cancer Driver No 61 0.138 368 53 0.144 2
STK11 STK11 Q15831 Serine/threonine-protein kinase STK11 chr19 GO:0017015 Census, Compendium Yes 75 0.173 135 14 0.104 9
TGFB1 TGFB1 P01137 Transforming growth factor beta-1 proprotein chr19 GO:0017015 Not Cancer Driver No 41 0.105 41 4 0.098 10
TGFB1I1 TGFB1I1 O43294 Transforming growth factor beta-1-induced transcript 1 protein chr16 GO:0017015 Not Cancer Driver No 61 0.132 219 34 0.155 0
TGFBR3_ENST00000525962 TGFBR3 Q03167 Transforming growth factor beta receptor type 3 chr1 GO:0017015 Not Cancer Driver No 129 0.152 268 41 0.153 0
THBS1 THBS1 P07996 Thrombospondin-1 chr15 GO:0017015 Not Cancer Driver No 188 0.161 320 58 0.181 0
TRIM33 TRIM33 Q9UPN9 E3 ubiquitin-protein ligase TRIM33 chr1 GO:0017015 Census, Compendium Yes 110 0.098 617 51 0.083 0
ZEB1_ENST00000320985 ZEB1 P37275 Zinc finger E-box-binding homeobox 1 chr10 GO:0017015 Census, Compendium Yes 246 0.219 831 200 0.241 8
ZEB2_ENST00000558170 ZEB2 O60315 Zinc finger E-box-binding homeobox 2 chr2 GO:0017015 Not Cancer Driver No 299 0.246 859 211 0.246 2
ZNF703 ZNF703 Q9H7S9 Zinc finger protein 703 chr8 GO:0017015 Not Cancer Driver No 26 0.044 415 14 0.034 0