Total number of protein in "GO:0016835" GO term: 76
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACO1_ENST00000541043 | ACO1 | P21399 | Cytoplasmic aconitate hydratase | chr9 | GO:0016835 | Not Cancer Driver | No | 108 | 0.121 | 44 | 14 | 0.318 | 0 |
| ACO2 | ACO2 | Q99798 | Aconitate hydratase, mitochondrial | chr22 | GO:0016835 | Not Cancer Driver | No | 94 | 0.121 | 172 | 19 | 0.11 | 5 |
| ALAD | ALAD | P13716 | Delta-aminolevulinic acid dehydratase | chr9 | GO:0016835 | Not Cancer Driver | No | 52 | 0.158 | 13 | 3 | 0.231 | 5 |
| ALKBH1 | ALKBH1 | Q13686 | Nucleic acid dioxygenase ALKBH1 | chr14 | GO:0016835 | Not Cancer Driver | No | 55 | 0.141 | 77 | 11 | 0.143 | 0 |
| ALOXE3_ENST00000448843 | ALOXE3 | Q9BYJ1 | Hydroperoxide isomerase ALOXE3 | chr17 | GO:0016835 | Not Cancer Driver | No | 108 | 0.152 | 69 | 13 | 0.188 | 6 |
| APIP | APIP | Q96GX9 | Methylthioribulose-1-phosphate dehydratase | chr11 | GO:0016835 | Not Cancer Driver | No | 24 | 0.099 | 26 | 1 | 0.038 | 0 |
| AUH | AUH | Q13825 | Methylglutaconyl-CoA hydratase, mitochondrial | chr9 | GO:0016835 | Not Cancer Driver | No | 34 | 0.1 | 29 | 0 | 0.0 | 1 |
| CA10_ENST00000285273 | CA10 | Q9NS85 | Carbonic anhydrase-related protein 10 | chr17 | GO:0016835 | Not Cancer Driver | No | 103 | 0.314 | 9 | 1 | 0.111 | 0 |
| CA11 | CA11 | O75493 | Carbonic anhydrase-related protein 11 | chr19 | GO:0016835 | Not Cancer Driver | No | 50 | 0.152 | 46 | 5 | 0.109 | 0 |
| CA12 | CA12 | O43570 | Carbonic anhydrase 12 | chr15 | GO:0016835 | Not Cancer Driver | No | 41 | 0.116 | 40 | 7 | 0.175 | 2 |
| CA13 | CA13 | Q8N1Q1 | Carbonic anhydrase 13 | chr8 | GO:0016835 | Not Cancer Driver | No | 36 | 0.137 | 56 | 7 | 0.125 | 0 |
| CA14 | CA14 | Q9ULX7 | Carbonic anhydrase 14 | chr1 | GO:0016835 | Not Cancer Driver | No | 51 | 0.151 | 104 | 14 | 0.135 | 0 |
| CA1_ENST00000431316 | CA1 | P00915 | Carbonic anhydrase 1 | chr8 | GO:0016835 | Not Cancer Driver | No | 50 | 0.192 | 100 | 18 | 0.18 | 0 |
| CA2 | CA2 | P00918 | Carbonic anhydrase 2 | chr8 | GO:0016835 | Not Cancer Driver | No | 41 | 0.158 | 55 | 8 | 0.145 | 4 |
| CA3 | CA3 | P07451 | Carbonic anhydrase 3 | chr8 | GO:0016835 | Not Cancer Driver | No | 61 | 0.235 | 64 | 13 | 0.203 | 0 |
| CA4 | CA4 | P22748 | Carbonic anhydrase 4 | chr17 | GO:0016835 | Not Cancer Driver | No | 55 | 0.176 | 81 | 12 | 0.148 | 4 |
| CA5A | CA5A | P35218 | Carbonic anhydrase 5A, mitochondrial | chr16 | GO:0016835 | Not Cancer Driver | No | 43 | 0.141 | 20 | 3 | 0.15 | 1 |
| CA5B_ENST00000454127 | CA5B | Q9Y2D0 | Carbonic anhydrase 5B, mitochondrial | chrX | GO:0016835 | Not Cancer Driver | No | 40 | 0.126 | 28 | 2 | 0.071 | 0 |
| CA6_ENST00000377443 | CA6 | P23280 | Carbonic anhydrase 6 | chr1 | GO:0016835 | Not Cancer Driver | No | 50 | 0.162 | 56 | 5 | 0.089 | 0 |
| CA7 | CA7 | P43166 | Carbonic anhydrase 7 | chr16 | GO:0016835 | Not Cancer Driver | No | 22 | 0.083 | 65 | 5 | 0.077 | 0 |
| CA8 | CA8 | P35219 | Carbonic anhydrase-related protein | chr8 | GO:0016835 | Not Cancer Driver | No | 56 | 0.193 | 32 | 2 | 0.062 | 1 |
| CA9 | CA9 | Q16790 | Carbonic anhydrase 9 | chr9 | GO:0016835 | Not Cancer Driver | No | 72 | 0.157 | 274 | 50 | 0.182 | 0 |
| CBS_ENST00000359624 | CBS | P35520 | Cystathionine beta-synthase | chr21 | GO:0016835 | Not Cancer Driver | No | 61 | 0.111 | 160 | 19 | 0.119 | 103 |
| CDYL_ENST00000328908 | CDYL | Q9Y232 | Chromodomain Y-like protein | chr6 | GO:0016835 | Not Cancer Driver | No | 99 | 0.166 | 346 | 61 | 0.176 | 0 |
| CYP1A1 | CYP1A1 | P04798 | Cytochrome P450 1A1 | chr15 | GO:0016835 | Not Cancer Driver | No | 81 | 0.158 | 17 | 2 | 0.118 | 0 |
| CYP1A2 | CYP1A2 | P05177 | Cytochrome P450 1A2 | chr15 | GO:0016835 | Not Cancer Driver | No | 93 | 0.18 | 23 | 3 | 0.13 | 0 |
| CYP1B1 | CYP1B1 | Q16678 | Cytochrome P450 1B1 | chr2 | GO:0016835 | Not Cancer Driver | No | 61 | 0.112 | 31 | 3 | 0.097 | 40 |
| CYP2S1 | CYP2S1 | Q96SQ9 | Cytochrome P450 2S1 | chr19 | GO:0016835 | Not Cancer Driver | No | 75 | 0.149 | 46 | 10 | 0.217 | 0 |
| DGLUCY_ENST00000428926 | DGLUCY | Q7Z3D6 | D-glutamate cyclase, mitochondrial | chr14 | GO:0016835 | Not Cancer Driver | No | 78 | 0.127 | 120 | 14 | 0.117 | 0 |
| ECHDC1 | ECHDC1 | Q9NTX5 | Ethylmalonyl-CoA decarboxylase | chr6 | GO:0016835 | Not Cancer Driver | No | 37 | 0.121 | 10 | 0 | 0.0 | 0 |
| ECHDC2 | ECHDC2 | Q86YB7 | Enoyl-CoA hydratase domain-containing protein 2, mitochondrial | chr1 | GO:0016835 | Not Cancer Driver | No | 43 | 0.147 | 10 | 1 | 0.1 | 0 |
| ECHDC3 | ECHDC3 | Q96DC8 | Enoyl-CoA hydratase domain-containing protein 3, mitochondrial | chr10 | GO:0016835 | Not Cancer Driver | No | 34 | 0.112 | 45 | 1 | 0.022 | 0 |
| ECHS1 | ECHS1 | P30084 | Enoyl-CoA hydratase, mitochondrial | chr10 | GO:0016835 | Not Cancer Driver | No | 51 | 0.176 | 7 | 1 | 0.143 | 14 |
| ECI1 | ECI1 | P42126 | Enoyl-CoA delta isomerase 1, mitochondrial | chr16 | GO:0016835 | Not Cancer Driver | No | 27 | 0.089 | 14 | 0 | 0.0 | 0 |
| EHHADH | EHHADH | Q08426 | Peroxisomal bifunctional enzyme | chr3 | GO:0016835 | Not Cancer Driver | No | 116 | 0.16 | 74 | 14 | 0.189 | 1 |
| ENO1 | ENO1 | P06733 | Alpha-enolase | chr1 | GO:0016835 | Not Cancer Driver | No | 51 | 0.118 | 21 | 2 | 0.095 | 0 |
| ENO2 | ENO2 | P09104 | Gamma-enolase | chr12 | GO:0016835 | Not Cancer Driver | No | 48 | 0.111 | 12 | 2 | 0.167 | 0 |
| ENO3 | ENO3 | P13929 | Beta-enolase | chr17 | GO:0016835 | Not Cancer Driver | No | 46 | 0.106 | 26 | 1 | 0.038 | 2 |
| ENO4 | ENO4 | A6NNW6 | Enolase 4 | chr10 | GO:0016835 | Not Cancer Driver | No | 13 | 0.021 | 197 | 4 | 0.02 | 0 |
| ENOSF1_ENST00000251101 | ENOSF1 | Q7L5Y1 | Mitochondrial enolase superfamily member 1 | chr18 | GO:0016835 | Not Cancer Driver | No | 62 | 0.14 | 25 | 2 | 0.08 | 0 |
| ETNPPL | ETNPPL | Q8TBG4 | Ethanolamine-phosphate phospho-lyase | chr4 | GO:0016835 | Not Cancer Driver | No | 92 | 0.184 | 80 | 14 | 0.175 | 0 |
| FASN | FASN | P49327 | Fatty acid synthase | chr17 | GO:0016835 | Not Cancer Driver | No | 291 | 0.116 | 309 | 42 | 0.136 | 0 |
| FH | FH | P07954 | Fumarate hydratase, mitochondrial | chr1 | GO:0016835 | Census, Compendium | Yes | 67 | 0.131 | 76 | 5 | 0.066 | 13 |
| GMDS | GMDS | O60547 | GDP-mannose 4,6 dehydratase | chr6 | GO:0016835 | Not Cancer Driver | No | 51 | 0.137 | 53 | 6 | 0.113 | 0 |
| HACD1 | HACD1 | B0YJ81 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1 | chr10 | GO:0016835 | Not Cancer Driver | No | 74 | 0.257 | 63 | 21 | 0.333 | 0 |
| HACD2 | HACD2 | Q6Y1H2 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 | chr3 | GO:0016835 | Not Cancer Driver | No | 16 | 0.063 | 14 | 0 | 0.0 | 0 |
| HACD3 | HACD3 | Q9P035 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 | chr15 | GO:0016835 | Not Cancer Driver | No | 28 | 0.077 | 10 | 0 | 0.0 | 0 |
| HACD4 | HACD4 | Q5VWC8 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 4 | chr9 | GO:0016835 | Not Cancer Driver | No | 30 | 0.129 | 0 | 0 | 0.0 | 0 |
| HADHA | HADHA | P40939 | Trifunctional enzyme subunit alpha, mitochondrial | chr2 | GO:0016835 | Not Cancer Driver | No | 72 | 0.094 | 19 | 2 | 0.105 | 5 |
| HADHB | HADHB | P55084 | Trifunctional enzyme subunit beta, mitochondrial | chr2 | GO:0016835 | Not Cancer Driver | No | 71 | 0.15 | 41 | 9 | 0.22 | 14 |
| HMGA2_ENST00000403681 | HMGA2 | P52926 | High mobility group protein HMGI-C | chr12 | GO:0016835 | Census | Yes | 12 | 0.11 | 109 | 12 | 0.11 | 0 |
| HSD17B4_ENST00000256216 | HSD17B4 | P51659 | Peroxisomal multifunctional enzyme type 2 | chr5 | GO:0016835 | Not Cancer Driver | No | 99 | 0.135 | 82 | 12 | 0.146 | 4 |
| HTD2_ENST00000461393 | HTD2 | P86397 | Hydroxyacyl-thioester dehydratase type 2, mitochondrial | chr3 | GO:0016835 | Not Cancer Driver | No | 1 | 0.006 | 0 | 0 | 0.0 | 0 |
| IREB2 | IREB2 | P48200 | Iron-responsive element-binding protein 2 | chr15 | GO:0016835 | Not Cancer Driver | No | 126 | 0.131 | 107 | 13 | 0.121 | 0 |
| L3HYPDH | L3HYPDH | Q96EM0 | Trans-3-hydroxy-L-proline dehydratase | chr14 | GO:0016835 | Not Cancer Driver | No | 39 | 0.11 | 28 | 3 | 0.107 | 0 |
| NEIL1_ENST00000564784 | NEIL1 | Q96FI4 | Endonuclease 8-like 1 | chr15 | GO:0016835 | Not Cancer Driver | No | 41 | 0.105 | 165 | 14 | 0.085 | 0 |
| NEIL2 | NEIL2 | Q969S2 | Endonuclease 8-like 2 | chr8 | GO:0016835 | Not Cancer Driver | No | 31 | 0.093 | 145 | 14 | 0.097 | 0 |
| NEIL3 | NEIL3 | Q8TAT5 | Endonuclease 8-like 3 | chr4 | GO:0016835 | Not Cancer Driver | No | 80 | 0.132 | 131 | 18 | 0.137 | 0 |
| NTHL1 | NTHL1 | P78549 | Endonuclease III-like protein 1 | chr16 | GO:0016835 | Census | Yes | 38 | 0.122 | 147 | 18 | 0.122 | 0 |
| OGG1_ENST00000344629 | OGG1 | O15527 | N-glycosylase/DNA lyase | chr3 | GO:0016835 | Not Cancer Driver | No | 37 | 0.107 | 71 | 12 | 0.169 | 0 |
| PARK7_ENST00000377488 | PARK7 | Q99497 | Parkinson disease protein 7 | chr1 | GO:0016835 | Not Cancer Driver | No | 11 | 0.058 | 30 | 0 | 0.0 | 5 |
| PCBD1 | PCBD1 | P61457 | Pterin-4-alpha-carbinolamine dehydratase | chr10 | GO:0016835 | Not Cancer Driver | No | 8 | 0.077 | 7 | 0 | 0.0 | 3 |
| PCBD2_ENST00000254908 | PCBD2 | Q9H0N5 | Pterin-4-alpha-carbinolamine dehydratase 2 | chr5 | GO:0016835 | Not Cancer Driver | No | 6 | 0.046 | 3 | 0 | 0.0 | 0 |
| POLL_ENST00000370169 | POLL | Q9UGP5 | DNA polymerase lambda | chr10 | GO:0016835 | Not Cancer Driver | No | 69 | 0.12 | 215 | 16 | 0.074 | 0 |
| POLQ | POLQ | O75417 | DNA polymerase theta | chr3 | GO:0016835 | Census, Compendium | Yes | 364 | 0.141 | 949 | 135 | 0.142 | 0 |
| PTGIS | PTGIS | Q16647 | Prostacyclin synthase | chr20 | GO:0016835 | Not Cancer Driver | No | 102 | 0.204 | 18 | 3 | 0.167 | 0 |
| PTS | PTS | Q03393 | 6-pyruvoyl tetrahydrobiopterin synthase | chr11 | GO:0016835 | Not Cancer Driver | No | 9 | 0.062 | 22 | 1 | 0.045 | 24 |
| RPS3_ENST00000527446 | RPS3 | P23396 | 40S ribosomal protein S3 | chr11 | GO:0016835 | Not Cancer Driver | No | 22 | 0.091 | 48 | 4 | 0.083 | 0 |
| TBXAS1_ENST00000448866 | TBXAS1 | P24557 | Thromboxane-A synthase | chr7 | GO:0016835 | Not Cancer Driver | No | 116 | 0.218 | 44 | 8 | 0.182 | 4 |
| TGDS | TGDS | O95455 | dTDP-D-glucose 4,6-dehydratase | chr13 | GO:0016835 | Not Cancer Driver | No | 43 | 0.123 | 29 | 2 | 0.069 | 5 |
| THNSL2 | THNSL2 | Q86YJ6 | Threonine synthase-like 2 | chr2 | GO:0016835 | Not Cancer Driver | No | 73 | 0.151 | 51 | 3 | 0.059 | 0 |
| TPI1_ENST00000396705 | TPI1 | P60174 | Triosephosphate isomerase | chr12 | GO:0016835 | Not Cancer Driver | No | 40 | 0.161 | 15 | 2 | 0.133 | 7 |
| UROC1_ENST00000290868 | UROC1 | Q96N76 | Urocanate hydratase | chr3 | GO:0016835 | Not Cancer Driver | No | 151 | 0.223 | 37 | 9 | 0.243 | 2 |
| UROS_ENST00000368786 | UROS | P10746 | Uroporphyrinogen-III synthase | chr10 | GO:0016835 | Not Cancer Driver | No | 34 | 0.128 | 7 | 0 | 0.0 | 21 |
| XRCC5_ENST00000392132 | XRCC5 | P13010 | X-ray repair cross-complementing protein 5 | chr2 | GO:0016835 | Not Cancer Driver | No | 87 | 0.119 | 118 | 11 | 0.093 | 0 |
| XRCC6 | XRCC6 | P12956 | X-ray repair cross-complementing protein 6 | chr22 | GO:0016835 | Not Cancer Driver | No | 66 | 0.108 | 140 | 12 | 0.086 | 0 |