Total number of protein in "GO:0016817" GO term: 100
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACYP1_ENST00000238618 | ACYP1 | P07311 | Acylphosphatase-1 | chr14 | GO:0016817 | Not Cancer Driver | No | 13 | 0.131 | 31 | 4 | 0.129 | 0 |
| ACYP2_ENST00000394666 | ACYP2 | P14621 | Acylphosphatase-2 | chr2 | GO:0016817 | Not Cancer Driver | No | 9 | 0.091 | 37 | 3 | 0.081 | 0 |
| ADPRM | ADPRM | Q3LIE5 | Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase | chr17 | GO:0016817 | Not Cancer Driver | No | 38 | 0.111 | 32 | 4 | 0.125 | 0 |
| ALPL | ALPL | P05186 | Alkaline phosphatase, tissue-nonspecific isozyme | chr1 | GO:0016817 | Not Cancer Driver | No | 80 | 0.153 | 184 | 39 | 0.212 | 113 |
| ARL8B | ARL8B | Q9NVJ2 | ADP-ribosylation factor-like protein 8B | chr3 | GO:0016817 | Not Cancer Driver | No | 28 | 0.151 | 0 | 0 | 0.0 | 0 |
| ASMTL | ASMTL | O95671 | Probable bifunctional dTTP/UTP pyrophosphatase/methyltransferase protein | chrX | GO:0016817 | Not Cancer Driver | No | 117 | 0.188 | 79 | 25 | 0.316 | 0 |
| CANT1 | CANT1 | Q8WVQ1 | Soluble calcium-activated nucleotidase 1 | chr17 | GO:0016817 | Census | Yes | 57 | 0.142 | 48 | 5 | 0.104 | 12 |
| CDC42_ENST00000344548 | CDC42 | P60953 | Cell division control protein 42 homolog | chr1 | GO:0016817 | Not Cancer Driver | No | 39 | 0.204 | 23 | 2 | 0.087 | 1 |
| DCP2 | DCP2 | Q8IU60 | m7GpppN-mRNA hydrolase | chr5 | GO:0016817 | Not Cancer Driver | No | 57 | 0.136 | 167 | 24 | 0.144 | 0 |
| DCPS | DCPS | Q96C86 | m7GpppX diphosphatase | chr11 | GO:0016817 | Not Cancer Driver | No | 48 | 0.142 | 53 | 6 | 0.113 | 1 |
| DCTPP1 | DCTPP1 | Q9H773 | dCTP pyrophosphatase 1 | chr16 | GO:0016817 | Not Cancer Driver | No | 14 | 0.082 | 88 | 9 | 0.102 | 0 |
| DDX3X_ENST00000629496 | DDX3X | O00571 | ATP-dependent RNA helicase DDX3X | chrX | GO:0016817 | Census, Compendium | Yes | 133 | 0.201 | 301 | 47 | 0.156 | 18 |
| DOLPP1 | DOLPP1 | Q86YN1 | Dolichyldiphosphatase 1 | chr9 | GO:0016817 | Not Cancer Driver | No | 21 | 0.088 | 2 | 0 | 0.0 | 0 |
| DUT | DUT | P33316 | Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial | chr15 | GO:0016817 | Not Cancer Driver | No | 19 | 0.075 | 128 | 8 | 0.062 | 0 |
| DXO_ENST00000375356 | DXO | O77932 | Decapping and exoribonuclease protein | chr6 | GO:0016817 | Not Cancer Driver | No | 46 | 0.116 | 143 | 17 | 0.119 | 0 |
| ENPP1 | ENPP1 | P22413 | Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 | chr6 | GO:0016817 | Not Cancer Driver | No | 148 | 0.16 | 101 | 5 | 0.05 | 33 |
| ENPP3_ENST00000357639 | ENPP3 | O14638 | Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 | chr6 | GO:0016817 | Not Cancer Driver | No | 146 | 0.167 | 57 | 12 | 0.211 | 0 |
| ENPP4 | ENPP4 | Q9Y6X5 | Bis(5'-adenosyl)-triphosphatase ENPP4 | chr6 | GO:0016817 | Not Cancer Driver | No | 79 | 0.174 | 20 | 4 | 0.2 | 0 |
| ENPP5 | ENPP5 | Q9UJA9 | Ectonucleotide pyrophosphatase/phosphodiesterase family member 5 | chr6 | GO:0016817 | Not Cancer Driver | No | 88 | 0.184 | 8 | 1 | 0.125 | 0 |
| ENTPD1_ENST00000371205 | ENTPD1 | P49961 | Ectonucleoside triphosphate diphosphohydrolase 1 | chr10 | GO:0016817 | Not Cancer Driver | No | 63 | 0.124 | 16 | 2 | 0.125 | 1 |
| ENTPD2 | ENTPD2 | Q9Y5L3 | Ectonucleoside triphosphate diphosphohydrolase 2 | chr9 | GO:0016817 | Not Cancer Driver | No | 36 | 0.073 | 32 | 0 | 0.0 | 0 |
| ENTPD3 | ENTPD3 | O75355 | Ectonucleoside triphosphate diphosphohydrolase 3 | chr3 | GO:0016817 | Not Cancer Driver | No | 64 | 0.121 | 14 | 2 | 0.143 | 0 |
| ENTPD4 | ENTPD4 | Q9Y227 | Ectonucleoside triphosphate diphosphohydrolase 4 | chr8 | GO:0016817 | Not Cancer Driver | No | 67 | 0.109 | 26 | 2 | 0.077 | 0 |
| ENTPD5 | ENTPD5 | O75356 | Nucleoside diphosphate phosphatase ENTPD5 | chr14 | GO:0016817 | Not Cancer Driver | No | 41 | 0.096 | 6 | 1 | 0.167 | 0 |
| ENTPD6 | ENTPD6 | O75354 | Ectonucleoside triphosphate diphosphohydrolase 6 | chr20 | GO:0016817 | Not Cancer Driver | No | 68 | 0.14 | 41 | 6 | 0.146 | 0 |
| ENTPD7 | ENTPD7 | Q9NQZ7 | Ectonucleoside triphosphate diphosphohydrolase 7 | chr10 | GO:0016817 | Not Cancer Driver | No | 90 | 0.149 | 26 | 3 | 0.115 | 0 |
| ENTPD8 | ENTPD8 | Q5MY95 | Ectonucleoside triphosphate diphosphohydrolase 8 | chr9 | GO:0016817 | Not Cancer Driver | No | 46 | 0.093 | 5 | 0 | 0.0 | 0 |
| ERAS_ENST00000636362 | ERAS | Q7Z444 | GTPase ERas | chrX | GO:0016817 | Not Cancer Driver | No | 42 | 0.18 | 29 | 4 | 0.138 | 0 |
| FHIT_ENST00000492590 | FHIT | P49789 | Bis(5'-adenosyl)-triphosphatase | chr3 | GO:0016817 | Census, Compendium | Yes | 35 | 0.238 | 45 | 9 | 0.2 | 0 |
| FITM2 | FITM2 | Q8N6M3 | Acyl-coenzyme A diphosphatase FITM2 | chr20 | GO:0016817 | Not Cancer Driver | No | 28 | 0.107 | 0 | 0 | 0.0 | 1 |
| GARS | GARS1 | P41250 | Glycine--tRNA ligase | chr7 | GO:0016817 | Not Cancer Driver | No | 61 | 0.083 | 75 | 9 | 0.12 | 17 |
| HRAS | HRAS | P01112 | GTPase HRas | chr11 | GO:0016817 | Census, Compendium | Yes | 107 | 0.566 | 16 | 4 | 0.25 | 18 |
| ITPA | ITPA | Q9BY32 | Inosine triphosphate pyrophosphatase | chr20 | GO:0016817 | Not Cancer Driver | No | 21 | 0.108 | 10 | 1 | 0.1 | 1 |
| KRAS | KRAS | P01116 | GTPase KRas | chr12 | GO:0016817 | Census, Compendium | Yes | 788 | 4.169 | 7 | 2 | 0.286 | 27 |
| LHPP | LHPP | Q9H008 | Phospholysine phosphohistidine inorganic pyrophosphate phosphatase | chr10 | GO:0016817 | Not Cancer Driver | No | 32 | 0.119 | 20 | 1 | 0.05 | 0 |
| MRAS_ENST00000423968 | MRAS | O14807 | Ras-related protein M-Ras | chr3 | GO:0016817 | Not Cancer Driver | No | 27 | 0.13 | 50 | 13 | 0.26 | 3 |
| NRAS | NRAS | P01111 | GTPase NRas | chr1 | GO:0016817 | Census, Compendium | Yes | 284 | 1.503 | 10 | 0 | 0.0 | 14 |
| NUDT10_ENST00000356450 | NUDT10 | Q8NFP7 | Diphosphoinositol polyphosphate phosphohydrolase 3-alpha | chrX | GO:0016817 | Not Cancer Driver | No | 29 | 0.177 | 68 | 8 | 0.118 | 0 |
| NUDT11 | NUDT11 | Q96G61 | Diphosphoinositol polyphosphate phosphohydrolase 3-beta | chrX | GO:0016817 | Not Cancer Driver | No | 30 | 0.183 | 65 | 13 | 0.2 | 0 |
| NUDT12 | NUDT12 | Q9BQG2 | NAD-capped RNA hydrolase NUDT12 | chr5 | GO:0016817 | Not Cancer Driver | No | 65 | 0.141 | 11 | 2 | 0.182 | 0 |
| NUDT13 | NUDT13 | Q86X67 | NAD(P)H pyrophosphatase NUDT13, mitochondrial | chr10 | GO:0016817 | Not Cancer Driver | No | 40 | 0.114 | 19 | 0 | 0.0 | 0 |
| NUDT14 | NUDT14 | O95848 | Uridine diphosphate glucose pyrophosphatase NUDT14 | chr14 | GO:0016817 | Not Cancer Driver | No | 27 | 0.122 | 39 | 8 | 0.205 | 0 |
| NUDT15 | NUDT15 | Q9NV35 | Nucleotide triphosphate diphosphatase NUDT15 | chr13 | GO:0016817 | Not Cancer Driver | No | 24 | 0.146 | 37 | 3 | 0.081 | 0 |
| NUDT16L1 | NUDT16L1 | Q9BRJ7 | Tudor-interacting repair regulator protein | chr16 | GO:0016817 | Not Cancer Driver | No | 16 | 0.076 | 6 | 0 | 0.0 | 0 |
| NUDT16_ENST00000521288 | NUDT16 | Q96DE0 | U8 snoRNA-decapping enzyme | chr3 | GO:0016817 | Not Cancer Driver | No | 29 | 0.149 | 8 | 1 | 0.125 | 0 |
| NUDT17 | NUDT17 | P0C025 | Nucleoside diphosphate-linked moiety X motif 17 | chr1 | GO:0016817 | Not Cancer Driver | No | 33 | 0.101 | 91 | 15 | 0.165 | 0 |
| NUDT18 | NUDT18 | Q6ZVK8 | 8-oxo-dGDP phosphatase NUDT18 | chr8 | GO:0016817 | Not Cancer Driver | No | 22 | 0.068 | 39 | 3 | 0.077 | 0 |
| NUDT19 | NUDT19 | A8MXV4 | Acyl-coenzyme A diphosphatase NUDT19 | chr19 | GO:0016817 | Not Cancer Driver | No | 27 | 0.072 | 131 | 5 | 0.038 | 0 |
| NUDT1_ENST00000397046 | NUDT1 | P36639 | Oxidized purine nucleoside triphosphate hydrolase | chr7 | GO:0016817 | Not Cancer Driver | No | 25 | 0.16 | 17 | 4 | 0.235 | 0 |
| NUDT22 | NUDT22 | Q9BRQ3 | Uridine diphosphate glucose pyrophosphatase NUDT22 | chr11 | GO:0016817 | Not Cancer Driver | No | 23 | 0.076 | 73 | 6 | 0.082 | 0 |
| NUDT2_ENST00000346365 | NUDT2 | P50583 | Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] | chr9 | GO:0016817 | Not Cancer Driver | No | 16 | 0.109 | 24 | 1 | 0.042 | 0 |
| NUDT3 | NUDT3 | O95989 | Diphosphoinositol polyphosphate phosphohydrolase 1 | chr6 | GO:0016817 | Not Cancer Driver | No | 22 | 0.128 | 38 | 5 | 0.132 | 0 |
| NUDT4B | NUDT4B | A0A024RBG1 | Diphosphoinositol polyphosphate phosphohydrolase NUDT4B | chr1 | GO:0016817 | Not Cancer Driver | No | 2 | 0.011 | 53 | 0 | 0.0 | 0 |
| NUDT4_ENST00000415493 | NUDT4 | Q9NZJ9 | Diphosphoinositol polyphosphate phosphohydrolase 2 | chr12 | GO:0016817 | Not Cancer Driver | No | 20 | 0.111 | 53 | 9 | 0.17 | 0 |
| NUDT5_ENST00000537776 | NUDT5 | Q9UKK9 | ADP-sugar pyrophosphatase | chr10 | GO:0016817 | Not Cancer Driver | No | 27 | 0.123 | 90 | 11 | 0.122 | 0 |
| NUDT6 | NUDT6 | P53370 | Nucleoside diphosphate-linked moiety X motif 6 | chr4 | GO:0016817 | Not Cancer Driver | No | 40 | 0.127 | 14 | 0 | 0.0 | 0 |
| NUDT7 | NUDT7 | P0C024 | Peroxisomal coenzyme A diphosphatase NUDT7 | chr16 | GO:0016817 | Not Cancer Driver | No | 45 | 0.189 | 42 | 4 | 0.095 | 0 |
| NUDT8 | NUDT8 | Q8WV74 | Mitochondrial coenzyme A diphosphatase NUDT8 | chr11 | GO:0016817 | Not Cancer Driver | No | 22 | 0.093 | 69 | 10 | 0.145 | 0 |
| NUDT9 | NUDT9 | Q9BW91 | ADP-ribose pyrophosphatase, mitochondrial | chr4 | GO:0016817 | Not Cancer Driver | No | 27 | 0.077 | 177 | 16 | 0.09 | 0 |
| PLPP1_ENST00000307259 | PLPP1 | O14494 | Phospholipid phosphatase 1 | chr5 | GO:0016817 | Not Cancer Driver | No | 28 | 0.099 | 27 | 1 | 0.037 | 0 |
| PLPP4 | PLPP4 | Q5VZY2 | Phospholipid phosphatase 4 | chr10 | GO:0016817 | Not Cancer Driver | No | 59 | 0.218 | 14 | 1 | 0.071 | 0 |
| PLPP5 | PLPP5 | Q8NEB5 | Phospholipid phosphatase 5 | chr8 | GO:0016817 | Not Cancer Driver | No | 22 | 0.083 | 0 | 0 | 0.0 | 0 |
| PPA1 | PPA1 | Q15181 | Inorganic pyrophosphatase | chr10 | GO:0016817 | Not Cancer Driver | No | 31 | 0.107 | 24 | 0 | 0.0 | 0 |
| PPA2 | PPA2 | Q9H2U2 | Inorganic pyrophosphatase 2, mitochondrial | chr4 | GO:0016817 | Not Cancer Driver | No | 49 | 0.147 | 71 | 9 | 0.127 | 9 |
| PRUNE1 | PRUNE1 | Q86TP1 | Exopolyphosphatase PRUNE1 | chr1 | GO:0016817 | Not Cancer Driver | No | 43 | 0.095 | 93 | 14 | 0.151 | 4 |
| RAB10 | RAB10 | P61026 | Ras-related protein Rab-10 | chr2 | GO:0016817 | Not Cancer Driver | No | 19 | 0.095 | 28 | 2 | 0.071 | 0 |
| RAB11A | RAB11A | P62491 | Ras-related protein Rab-11A | chr15 | GO:0016817 | Not Cancer Driver | No | 31 | 0.144 | 43 | 4 | 0.093 | 0 |
| RAB11B | RAB11B | Q15907 | Ras-related protein Rab-11B | chr19 | GO:0016817 | Not Cancer Driver | No | 26 | 0.119 | 39 | 3 | 0.077 | 2 |
| RAB1A | RAB1A | P62820 | Ras-related protein Rab-1A | chr2 | GO:0016817 | Not Cancer Driver | No | 16 | 0.078 | 38 | 2 | 0.053 | 0 |
| RAB1B | RAB1B | Q9H0U4 | Ras-related protein Rab-1B | chr11 | GO:0016817 | Not Cancer Driver | No | 24 | 0.119 | 40 | 3 | 0.075 | 0 |
| RAB27A_ENST00000336787 | RAB27A | P51159 | Ras-related protein Rab-27A | chr15 | GO:0016817 | Not Cancer Driver | No | 25 | 0.113 | 15 | 4 | 0.267 | 3 |
| RAB27B | RAB27B | O00194 | Ras-related protein Rab-27B | chr18 | GO:0016817 | Not Cancer Driver | No | 42 | 0.193 | 43 | 9 | 0.209 | 0 |
| RAB4A | RAB4A | P20338 | Ras-related protein Rab-4A | chr1 | GO:0016817 | Not Cancer Driver | No | 26 | 0.119 | 32 | 11 | 0.344 | 0 |
| RAB4B_ENST00000357052 | RAB4B | P61018 | Ras-related protein Rab-4B | chr19 | GO:0016817 | Not Cancer Driver | No | 40 | 0.188 | 36 | 10 | 0.278 | 0 |
| RAB5A | RAB5A | P20339 | Ras-related protein Rab-5A | chr3 | GO:0016817 | Not Cancer Driver | No | 32 | 0.149 | 65 | 15 | 0.231 | 0 |
| RAB5B | RAB5B | P61020 | Ras-related protein Rab-5B | chr12 | GO:0016817 | Not Cancer Driver | No | 23 | 0.107 | 43 | 5 | 0.116 | 0 |
| RAB5C_ENST00000393860 | RAB5C | P51148 | Ras-related protein Rab-5C | chr17 | GO:0016817 | Not Cancer Driver | No | 24 | 0.111 | 50 | 4 | 0.08 | 0 |
| RAB7A | RAB7A | P51149 | Ras-related protein Rab-7a | chr3 | GO:0016817 | Not Cancer Driver | No | 27 | 0.13 | 11 | 0 | 0.0 | 4 |
| RAC1_ENST00000348035 | RAC1 | P63000 | Ras-related C3 botulinum toxin substrate 1 | chr7 | GO:0016817 | Census, Compendium | Yes | 66 | 0.344 | 2 | 1 | 0.5 | 6 |
| RAC3 | RAC3 | P60763 | Ras-related C3 botulinum toxin substrate 3 | chr17 | GO:0016817 | Not Cancer Driver | No | 24 | 0.125 | 0 | 0 | 0.0 | 4 |
| RALA | RALA | P11233 | Ras-related protein Ral-A | chr7 | GO:0016817 | Not Cancer Driver | No | 34 | 0.165 | 34 | 3 | 0.088 | 5 |
| RALB | RALB | P11234 | Ras-related protein Ral-B | chr2 | GO:0016817 | Not Cancer Driver | No | 36 | 0.175 | 35 | 5 | 0.143 | 0 |
| RAP1A_ENST00000356415 | RAP1A | P62834 | Ras-related protein Rap-1A | chr1 | GO:0016817 | Not Cancer Driver | No | 27 | 0.147 | 5 | 0 | 0.0 | 0 |
| RAP1B_ENST00000393436 | RAP1B | P61224 | Ras-related protein Rap-1b | chr12 | GO:0016817 | Not Cancer Driver | No | 26 | 0.141 | 14 | 3 | 0.214 | 0 |
| RAP2A | RAP2A | P10114 | Ras-related protein Rap-2a | chr13 | GO:0016817 | Not Cancer Driver | No | 15 | 0.082 | 9 | 0 | 0.0 | 0 |
| RAP2B | RAP2B | P61225 | Ras-related protein Rap-2b | chr3 | GO:0016817 | Not Cancer Driver | No | 22 | 0.12 | 0 | 0 | 0.0 | 0 |
| RAP2C_ENST00000370874 | RAP2C | Q9Y3L5 | Ras-related protein Rap-2c | chrX | GO:0016817 | Not Cancer Driver | No | 32 | 0.175 | 8 | 2 | 0.25 | 0 |
| RASL10A | RASL10A | Q92737 | Ras-like protein family member 10A | chr22 | GO:0016817 | Not Cancer Driver | No | 13 | 0.064 | 40 | 0 | 0.0 | 0 |
| RASL11A | RASL11A | Q6T310 | Ras-like protein family member 11A | chr13 | GO:0016817 | Not Cancer Driver | No | 31 | 0.128 | 40 | 6 | 0.15 | 0 |
| RASL11B | RASL11B | Q9BPW5 | Ras-like protein family member 11B | chr4 | GO:0016817 | Not Cancer Driver | No | 24 | 0.097 | 33 | 4 | 0.121 | 0 |
| RASL12 | RASL12 | Q9NYN1 | Ras-like protein family member 12 | chr15 | GO:0016817 | Not Cancer Driver | No | 37 | 0.139 | 49 | 8 | 0.163 | 0 |
| RERGL | RERGL | Q9H628 | Ras-related and estrogen-regulated growth inhibitor-like protein | chr12 | GO:0016817 | Not Cancer Driver | No | 57 | 0.278 | 0 | 0 | 0.0 | 0 |
| RERG_ENST00000538313 | RERG | Q96A58 | Ras-related and estrogen-regulated growth inhibitor | chr12 | GO:0016817 | Not Cancer Driver | No | 42 | 0.211 | 39 | 10 | 0.256 | 0 |
| RHOA | RHOA | P61586 | Transforming protein RhoA | chr3 | GO:0016817 | Census, Compendium | Yes | 99 | 0.513 | 46 | 13 | 0.283 | 2 |
| RIT1_ENST00000368323 | RIT1 | Q92963 | GTP-binding protein Rit1 | chr1 | GO:0016817 | Not Cancer Driver | No | 34 | 0.155 | 43 | 3 | 0.07 | 5 |
| RIT2 | RIT2 | Q99578 | GTP-binding protein Rit2 | chr18 | GO:0016817 | Not Cancer Driver | No | 74 | 0.341 | 29 | 11 | 0.379 | 0 |
| RNGTT | RNGTT | O60942 | mRNA-capping enzyme | chr6 | GO:0016817 | Not Cancer Driver | No | 69 | 0.116 | 112 | 12 | 0.107 | 0 |
| SLC25A42 | SLC25A42 | Q86VD7 | Mitochondrial coenzyme A transporter SLC25A42 | chr19 | GO:0016817 | Not Cancer Driver | No | 42 | 0.132 | 12 | 2 | 0.167 | 1 |
| THTPA | THTPA | Q9BU02 | Thiamine-triphosphatase | chr14 | GO:0016817 | Not Cancer Driver | No | 19 | 0.083 | 56 | 4 | 0.071 | 0 |
| TRPM2_ENST00000397928 | TRPM2 | O94759 | Transient receptor potential cation channel subfamily M member 2 | chr21 | GO:0016817 | Not Cancer Driver | No | 286 | 0.19 | 266 | 44 | 0.165 | 0 |