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Total number of protein in "GO:0016788" GO term:  516

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
AARS AARS1 P49588 Alanine--tRNA ligase, cytoplasmic chr16 GO:0016788 Not Cancer Driver No 97 0.1 140 14 0.1 5
AARS2 AARS2 Q5JTZ9 Alanine--tRNA ligase, mitochondrial chr6 GO:0016788 Not Cancer Driver No 123 0.125 203 25 0.123 5
AARSD1 AARSD1 Q9BTE6 Alanyl-tRNA editing protein Aarsd1 chr17 GO:0016788 Not Cancer Driver No 40 0.097 157 20 0.127 0
ABCD1 ABCD1 P33897 ATP-binding cassette sub-family D member 1 chrX GO:0016788 Not Cancer Driver No 106 0.142 75 5 0.067 138
ABCD2 ABCD2 Q9UBJ2 ATP-binding cassette sub-family D member 2 chr12 GO:0016788 Not Cancer Driver No 150 0.203 29 4 0.138 0
ABCD3 ABCD3 P28288 ATP-binding cassette sub-family D member 3 chr1 GO:0016788 Not Cancer Driver No 75 0.114 21 2 0.095 0
ABHD1 ABHD1 Q96SE0 Protein ABHD1 chr2 GO:0016788 Not Cancer Driver No 43 0.106 26 3 0.115 0
ABHD10 ABHD10 Q9NUJ1 Palmitoyl-protein thioesterase ABHD10, mitochondrial chr3 GO:0016788 Not Cancer Driver No 38 0.124 7 2 0.286 0
ABHD12B ABHD12B Q7Z5M8 Protein ABHD12B chr14 GO:0016788 Not Cancer Driver No 34 0.094 16 1 0.062 0
ABHD12_ENST00000339157 ABHD12 Q8N2K0 Lysophosphatidylserine lipase ABHD12 chr20 GO:0016788 Not Cancer Driver No 45 0.113 8 1 0.125 1
ABHD13 ABHD13 Q7L211 Protein ABHD13 chr13 GO:0016788 Not Cancer Driver No 53 0.157 0 0 0.0 0
ABHD15 ABHD15 Q6UXT9 Protein ABHD15 chr17 GO:0016788 Not Cancer Driver No 50 0.107 41 3 0.073 0
ABHD16A ABHD16A O95870 Phosphatidylserine lipase ABHD16A chr6 GO:0016788 Not Cancer Driver No 69 0.124 53 15 0.283 0
ABHD16B ABHD16B Q9H3Z7 Protein ABHD16B chr20 GO:0016788 Not Cancer Driver No 41 0.087 31 2 0.065 0
ABHD17A_ENST00000292577 ABHD17A Q96GS6 Alpha/beta hydrolase domain-containing protein 17A chr19 GO:0016788 Not Cancer Driver No 35 0.113 20 5 0.25 0
ABHD17B_ENST00000333421 ABHD17B Q5VST6 Alpha/beta hydrolase domain-containing protein 17B chr9 GO:0016788 Not Cancer Driver No 35 0.122 0 0 0.0 0
ABHD17C ABHD17C Q6PCB6 Alpha/beta hydrolase domain-containing protein 17C chr15 GO:0016788 Not Cancer Driver No 21 0.064 53 0 0.0 0
ABHD2_ENST00000565973 ABHD2 P08910 Monoacylglycerol lipase ABHD2 chr15 GO:0016788 Not Cancer Driver No 54 0.127 8 1 0.125 0
ABHD3 ABHD3 Q8WU67 Phospholipase ABHD3 chr18 GO:0016788 Not Cancer Driver No 43 0.105 0 0 0.0 0
ACAA2 ACAA2 P42765 3-ketoacyl-CoA thiolase, mitochondrial chr18 GO:0016788 Not Cancer Driver No 42 0.106 51 2 0.039 0
ACHE_ENST00000241069 ACHE P22303 Acetylcholinesterase chr7 GO:0016788 Not Cancer Driver No 81 0.132 64 8 0.125 0
ACOT1 ACOT1 Q86TX2 Acyl-coenzyme A thioesterase 1 chr14 GO:0016788 Not Cancer Driver No 28 0.067 22 0 0.0 0
ACOT11 ACOT11 Q8WXI4 Acyl-coenzyme A thioesterase 11 chr1 GO:0016788 Not Cancer Driver No 88 0.145 110 19 0.173 0
ACOT12 ACOT12 Q8WYK0 Acetyl-coenzyme A thioesterase chr5 GO:0016788 Not Cancer Driver No 93 0.168 41 3 0.073 0
ACOT13 ACOT13 Q9NPJ3 Acyl-coenzyme A thioesterase 13 chr6 GO:0016788 Not Cancer Driver No 15 0.107 23 2 0.087 0
ACOT2 ACOT2 P49753 Acyl-coenzyme A thioesterase 2, mitochondrial chr14 GO:0016788 Not Cancer Driver No 49 0.101 35 5 0.143 0
ACOT4 ACOT4 Q8N9L9 Peroxisomal succinyl-coenzyme A thioesterase chr14 GO:0016788 Not Cancer Driver No 53 0.126 13 1 0.077 0
ACOT6_ENST00000645972 ACOT6 Q3I5F7 Acyl-coenzyme A thioesterase 6 chr14 GO:0016788 Not Cancer Driver No 30 0.071 18 0 0.0 0
ACOT7 ACOT7 O00154 Cytosolic acyl coenzyme A thioester hydrolase chr1 GO:0016788 Not Cancer Driver No 43 0.113 77 16 0.208 0
ACOT8 ACOT8 O14734 Acyl-coenzyme A thioesterase 8 chr20 GO:0016788 Not Cancer Driver No 43 0.135 52 7 0.135 0
ACOT9_ENST00000336430 ACOT9 Q9Y305 Acyl-coenzyme A thioesterase 9, mitochondrial chrX GO:0016788 Not Cancer Driver No 45 0.103 45 3 0.067 0
ACP1_ENST00000272065 ACP1 P24666 Low molecular weight phosphotyrosine protein phosphatase chr2 GO:0016788 Not Cancer Driver No 28 0.177 13 2 0.154 0
ACP2 ACP2 P11117 Lysosomal acid phosphatase chr11 GO:0016788 Not Cancer Driver No 41 0.097 77 11 0.143 0
ACP4 ACP4 Q9BZG2 Testicular acid phosphatase chr19 GO:0016788 Not Cancer Driver No 66 0.155 28 7 0.25 3
ACP5_ENST00000433365 ACP5 P13686 Tartrate-resistant acid phosphatase type 5 chr19 GO:0016788 Not Cancer Driver No 51 0.157 31 6 0.194 8
ACP6 ACP6 Q9NPH0 Lysophosphatidic acid phosphatase type 6 chr1 GO:0016788 Not Cancer Driver No 53 0.124 40 5 0.125 0
ACP7 ACP7 Q6ZNF0 Acid phosphatase type 7 chr19 GO:0016788 Not Cancer Driver No 72 0.164 22 7 0.318 0
ACPP_ENST00000336375 ACP3 P15309 Prostatic acid phosphatase chr3 GO:0016788 Not Cancer Driver No 81 0.21 24 5 0.208 0
ACSBG2_ENST00000591403 ACSBG2 Q5FVE4 Long-chain-fatty-acid--CoA ligase ACSBG2 chr19 GO:0016788 Not Cancer Driver No 119 0.179 37 9 0.243 0
ACY3 ACY3 Q96HD9 N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming) chr11 GO:0016788 Not Cancer Driver No 49 0.154 68 7 0.103 0
ADPRM ADPRM Q3LIE5 Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase chr17 GO:0016788 Not Cancer Driver No 38 0.111 32 4 0.125 0
AGO2 AGO2 Q9UKV8 Protein argonaute-2 chr8 GO:0016788 Not Cancer Driver No 126 0.147 141 15 0.106 11
AGO3 AGO3 Q9H9G7 Protein argonaute-3 chr1 GO:0016788 Not Cancer Driver No 110 0.128 143 19 0.133 0
AL121900.2 AL121900.2 A0A087WZV9 D-aminoacyl-tRNA deacylase (Fragment) chr20 GO:0016788 Not Cancer Driver No 41 0.184 77 19 0.247 0
ALPG ALPG P10696 Alkaline phosphatase, germ cell type chr2 GO:0016788 Not Cancer Driver No 85 0.16 153 33 0.216 0
ALPI ALPI P09923 Intestinal-type alkaline phosphatase chr2 GO:0016788 Not Cancer Driver No 94 0.178 157 36 0.229 0
ALPL ALPL P05186 Alkaline phosphatase, tissue-nonspecific isozyme chr1 GO:0016788 Not Cancer Driver No 80 0.153 184 39 0.212 113
ALPP ALPP P05187 Alkaline phosphatase, placental type chr2 GO:0016788 Not Cancer Driver No 120 0.224 161 40 0.248 0
AOAH_ENST00000617537 AOAH P28039 Acyloxyacyl hydrolase chr7 GO:0016788 Not Cancer Driver No 111 0.193 68 10 0.147 0
APEX1_ENST00000555414 APEX1 P27695 DNA-(apurinic or apyrimidinic site) endonuclease chr14 GO:0016788 Not Cancer Driver No 34 0.107 103 14 0.136 0
APEX2 APEX2 Q9UBZ4 DNA-(apurinic or apyrimidinic site) endonuclease 2 chrX GO:0016788 Not Cancer Driver No 66 0.127 148 14 0.095 0
APMAP APMAP Q9HDC9 Adipocyte plasma membrane-associated protein chr20 GO:0016788 Not Cancer Driver No 66 0.159 72 11 0.153 0
APTX_ENST00000379819 APTX Q7Z2E3 Aprataxin chr9 GO:0016788 Not Cancer Driver No 36 0.101 101 6 0.059 9
ARMT1 ARMT1 Q9H993 Damage-control phosphatase ARMT1 chr6 GO:0016788 Not Cancer Driver No 53 0.12 1 0 0.0 0
ARSA ARSA P15289 Arylsulfatase A chr22 GO:0016788 Not Cancer Driver No 46 0.091 61 7 0.115 97
ARSB ARSB P15848 Arylsulfatase B chr5 GO:0016788 Not Cancer Driver No 59 0.111 81 6 0.074 29
ARSD ARSD P51689 Arylsulfatase D chrX GO:0016788 Not Cancer Driver No 75 0.126 70 10 0.143 0
ARSE_ENST00000381134 ARSL P51690 Arylsulfatase L chrX GO:0016788 Not Cancer Driver No 85 0.144 4 1 0.25 9
ARSF_ENST00000359361 ARSF P54793 Arylsulfatase F chrX GO:0016788 Not Cancer Driver No 132 0.224 43 10 0.233 0
ARSG_ENST00000621439 ARSG Q96EG1 Arylsulfatase G chr17 GO:0016788 Not Cancer Driver No 86 0.164 66 10 0.152 1
ARSH ARSH Q5FYA8 Arylsulfatase H chrX GO:0016788 Not Cancer Driver No 84 0.149 13 4 0.308 0
ARSI ARSI Q5FYB1 Arylsulfatase I chr5 GO:0016788 Not Cancer Driver No 85 0.149 86 15 0.174 0
ARSJ ARSJ Q5FYB0 Arylsulfatase J chr4 GO:0016788 Not Cancer Driver No 70 0.117 142 17 0.12 0
ARSK ARSK Q6UWY0 Arylsulfatase K chr5 GO:0016788 Not Cancer Driver No 70 0.131 9 2 0.222 0
ASPA ASPA P45381 Aspartoacylase chr17 GO:0016788 Not Cancer Driver No 58 0.185 3 0 0.0 42
ASPG ASPG Q86U10 60 kDa lysophospholipase chr14 GO:0016788 Not Cancer Driver No 68 0.119 76 13 0.171 0
BAAT_ENST00000395051 BAAT Q14032 Bile acid-CoA:amino acid N-acyltransferase chr9 GO:0016788 Not Cancer Driver No 88 0.211 10 4 0.4 1
BCHE BCHE P06276 Cholinesterase chr3 GO:0016788 Not Cancer Driver No 185 0.307 14 4 0.286 38
BDKRB2 BDKRB2 P30411 B2 bradykinin receptor chr14 GO:0016788 Not Cancer Driver No 81 0.207 0 0 0.0 0
BPHL BPHL Q86WA6 Valacyclovir hydrolase chr6 GO:0016788 Not Cancer Driver No 35 0.12 12 1 0.083 0
BPNT1_ENST00000322067 BPNT1 O95861 3'(2'),5'-bisphosphate nucleotidase 1 chr1 GO:0016788 Not Cancer Driver No 44 0.143 9 0 0.0 0
C11orf54_ENST00000354421 C11orf54 Q9H0W9 Ester hydrolase C11orf54 chr11 GO:0016788 Not Cancer Driver No 23 0.073 23 0 0.0 0
CA1_ENST00000431316 CA1 P00915 Carbonic anhydrase 1 chr8 GO:0016788 Not Cancer Driver No 50 0.192 100 18 0.18 0
CA2 CA2 P00918 Carbonic anhydrase 2 chr8 GO:0016788 Not Cancer Driver No 41 0.158 55 8 0.145 4
CAMK2G_ENST00000423381 CAMK2G Q13555 Calcium/calmodulin-dependent protein kinase type II subunit gamma chr10 GO:0016788 Not Cancer Driver No 68 0.122 145 14 0.097 1
CASR_ENST00000638421 CASR P41180 Extracellular calcium-sensing receptor chr3 GO:0016788 Not Cancer Driver No 304 0.282 189 60 0.317 108
CCR1 CCR1 P32246 C-C chemokine receptor type 1 chr3 GO:0016788 Not Cancer Driver No 69 0.194 14 5 0.357 0
CCR5 CCR5 P51681 C-C chemokine receptor type 5 chr3 GO:0016788 Not Cancer Driver No 107 0.304 0 0 0.0 0
CDC14A_ENST00000336454 CDC14A Q9UNH5 Dual specificity protein phosphatase CDC14A chr1 GO:0016788 Not Cancer Driver No 91 0.153 246 43 0.175 3
CDC14B CDC14B O60729 Dual specificity protein phosphatase CDC14B chr9 GO:0016788 Not Cancer Driver No 61 0.122 138 15 0.109 0
CDKN3 CDKN3 Q16667 Cyclin-dependent kinase inhibitor 3 chr14 GO:0016788 Not Cancer Driver No 13 0.061 33 1 0.03 9
CEL CEL P19835 Bile salt-activated lipase chr9 GO:0016788 Not Cancer Driver No 101 0.134 280 40 0.143 0
CES1_ENST00000361503 CES1 P23141 Liver carboxylesterase 1 chr16 GO:0016788 Not Cancer Driver No 138 0.243 41 2 0.049 0
CES3 CES3 Q6UWW8 Carboxylesterase 3 chr16 GO:0016788 Not Cancer Driver No 94 0.165 112 13 0.116 0
CES5A_ENST00000290567 CES5A Q6NT32 Carboxylesterase 5A chr16 GO:0016788 Not Cancer Driver No 115 0.2 18 2 0.111 0
CHKA CHKA P35790 Choline kinase alpha chr11 GO:0016788 Not Cancer Driver No 45 0.098 119 4 0.034 0
CHRM1 CHRM1 P11229 Muscarinic acetylcholine receptor M1 chr11 GO:0016788 Not Cancer Driver No 63 0.137 131 24 0.183 0
CHRM3_ENST00000615928 CHRM3 P20309 Muscarinic acetylcholine receptor M3 chr1 GO:0016788 Not Cancer Driver No 182 0.308 136 42 0.309 0
CHRM5 CHRM5 P08912 Muscarinic acetylcholine receptor M5 chr15 GO:0016788 Not Cancer Driver No 74 0.139 155 20 0.129 0
CILP CILP O75339 Cartilage intermediate layer protein 1 chr15 GO:0016788 Not Cancer Driver No 206 0.174 278 44 0.158 0
CILP2 CILP2 Q8IUL8 Cartilage intermediate layer protein 2 chr19 GO:0016788 Not Cancer Driver No 207 0.179 401 86 0.214 0
CNOT1 CNOT1 A5YKK6 CCR4-NOT transcription complex subunit 1 chr16 GO:0016788 Not Cancer Driver No 346 0.146 464 56 0.121 12
CNOT2 CNOT2 Q9NZN8 CCR4-NOT transcription complex subunit 2 chr12 GO:0016788 Not Cancer Driver No 84 0.156 354 66 0.186 0
CNOT6L CNOT6L Q96LI5 CCR4-NOT transcription complex subunit 6-like chr4 GO:0016788 Not Cancer Driver No 58 0.105 37 3 0.081 0
CNOT6_ENST00000261951 CNOT6 Q9ULM6 CCR4-NOT transcription complex subunit 6 chr5 GO:0016788 Not Cancer Driver No 65 0.117 66 4 0.061 0
CNOT7 CNOT7 Q9UIV1 CCR4-NOT transcription complex subunit 7 chr8 GO:0016788 Not Cancer Driver No 31 0.109 21 1 0.048 0
CNOT8 CNOT8 Q9UFF9 CCR4-NOT transcription complex subunit 8 chr5 GO:0016788 Not Cancer Driver No 30 0.103 6 0 0.0 0
CNP CNP P09543 2',3'-cyclic-nucleotide 3'-phosphodiesterase chr17 GO:0016788 Not Cancer Driver No 36 0.086 71 2 0.028 0
CPSF3 CPSF3 Q9UKF6 Cleavage and polyadenylation specificity factor subunit 3 chr2 GO:0016788 Not Cancer Driver No 78 0.114 56 9 0.161 0
CTDP1 CTDP1 Q9Y5B0 RNA polymerase II subunit A C-terminal domain phosphatase chr18 GO:0016788 Not Cancer Driver No 121 0.126 624 87 0.139 0
CTDSP1 CTDSP1 Q9GZU7 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 chr2 GO:0016788 Not Cancer Driver No 34 0.13 46 2 0.043 0
CTDSP2 CTDSP2 O14595 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 chr12 GO:0016788 Not Cancer Driver No 35 0.129 18 0 0.0 0
CTDSPL CTDSPL O15194 CTD small phosphatase-like protein chr3 GO:0016788 Not Cancer Driver No 32 0.116 60 4 0.067 0
CTDSPL2 CTDSPL2 Q05D32 CTD small phosphatase-like protein 2 chr15 GO:0016788 Not Cancer Driver No 47 0.101 256 27 0.105 0
DBR1 DBR1 Q9UK59 Lariat debranching enzyme chr3 GO:0016788 Not Cancer Driver No 58 0.107 185 28 0.151 3
DCLRE1A DCLRE1A Q6PJP8 DNA cross-link repair 1A protein chr10 GO:0016788 Not Cancer Driver No 92 0.088 514 45 0.088 0
DCLRE1B DCLRE1B Q9H816 5' exonuclease Apollo chr1 GO:0016788 Not Cancer Driver No 65 0.122 127 17 0.134 0
DCLRE1C DCLRE1C Q96SD1 Protein artemis chr10 GO:0016788 Not Cancer Driver No 76 0.11 277 26 0.094 3
DCP2 DCP2 Q8IU60 m7GpppN-mRNA hydrolase chr5 GO:0016788 Not Cancer Driver No 57 0.136 167 24 0.144 0
DCPS DCPS Q96C86 m7GpppX diphosphatase chr11 GO:0016788 Not Cancer Driver No 48 0.142 53 6 0.113 1
DICER1 DICER1 Q9UPY3 Endoribonuclease Dicer chr14 GO:0016788 Census, Compendium Yes 264 0.137 362 45 0.124 4
DNA2 DNA2 P51530 DNA replication ATP-dependent helicase/nuclease DNA2 chr10 GO:0016788 Not Cancer Driver No 120 0.113 52 8 0.154 3
DNASE1L1 DNASE1L1 P49184 Deoxyribonuclease-1-like 1 chrX GO:0016788 Not Cancer Driver No 30 0.099 0 0 0.0 0
DNASE1L2_ENST00000567494 DNASE1L2 Q92874 Deoxyribonuclease-1-like 2 chr16 GO:0016788 Not Cancer Driver No 23 0.077 15 1 0.067 0
DNASE1L3 DNASE1L3 Q13609 Deoxyribonuclease gamma chr3 GO:0016788 Not Cancer Driver No 43 0.141 15 4 0.267 0
DNASE1_ENST00000246949 DNASE1 P24855 Deoxyribonuclease-1 chr16 GO:0016788 Not Cancer Driver No 24 0.085 0 0 0.0 0
DNASE2 DNASE2 O00115 Deoxyribonuclease-2-alpha chr19 GO:0016788 Not Cancer Driver No 46 0.128 48 7 0.146 0
DNASE2B DNASE2B Q8WZ79 Deoxyribonuclease-2-beta chr1 GO:0016788 Not Cancer Driver No 53 0.147 14 1 0.071 0
DPH7 DPH7 Q9BTV6 Diphthine methyltransferase chr9 GO:0016788 Not Cancer Driver No 38 0.084 107 10 0.093 0
DROSHA_ENST00000344624 DROSHA Q9NRR4 Ribonuclease 3 chr5 GO:0016788 Census, Compendium Yes 175 0.127 682 100 0.147 0
DTD1 DTD1 Q8TEA8 D-aminoacyl-tRNA deacylase 1 chr20 GO:0016788 Not Cancer Driver No 45 0.215 93 26 0.28 0
DTD2_ENST00000356180 DTD2 Q96FN9 D-aminoacyl-tRNA deacylase 2 chr14 GO:0016788 Not Cancer Driver No 12 0.071 11 1 0.091 0
DUPD1 DUSP29 Q68J44 Dual specificity phosphatase 29 chr10 GO:0016788 Not Cancer Driver No 47 0.214 55 7 0.127 0
DUSP1 DUSP1 P28562 Dual specificity protein phosphatase 1 chr5 GO:0016788 Not Cancer Driver No 31 0.084 7 0 0.0 0
DUSP10 DUSP10 Q9Y6W6 Dual specificity protein phosphatase 10 chr1 GO:0016788 Not Cancer Driver No 81 0.168 135 24 0.178 0
DUSP11 DUSP11 O75319 RNA/RNP complex-1-interacting phosphatase chr2 GO:0016788 Not Cancer Driver No 42 0.111 157 12 0.076 0
DUSP12 DUSP12 Q9UNI6 Dual specificity protein phosphatase 12 chr1 GO:0016788 Not Cancer Driver No 33 0.097 30 1 0.033 0
DUSP13_ENST00000472493 DUSP13 Q9UII6 Dual specificity protein phosphatase 13 isoform B chr10 GO:0016788 Not Cancer Driver No 45 0.227 16 1 0.062 0
DUSP15 DUSP15 Q9H1R2 Dual specificity protein phosphatase 15 chr20 GO:0016788 Not Cancer Driver No 36 0.122 122 19 0.156 0
DUSP16 DUSP16 Q9BY84 Dual specificity protein phosphatase 16 chr12 GO:0016788 Compendium Yes 70 0.105 273 34 0.125 0
DUSP18_ENST00000404885 DUSP18 Q8NEJ0 Dual specificity protein phosphatase 18 chr22 GO:0016788 Not Cancer Driver No 18 0.096 0 0 0.0 0
DUSP19 DUSP19 Q8WTR2 Dual specificity protein phosphatase 19 chr2 GO:0016788 Not Cancer Driver No 34 0.157 15 5 0.333 0
DUSP2 DUSP2 Q05923 Dual specificity protein phosphatase 2 chr2 GO:0016788 Not Cancer Driver No 24 0.076 23 3 0.13 0
DUSP21 DUSP21 Q9H596 Dual specificity protein phosphatase 21 chrX GO:0016788 Not Cancer Driver No 49 0.258 0 0 0.0 0
DUSP22_ENST00000344450 DUSP22 Q9NRW4 Dual specificity protein phosphatase 22 chr6 GO:0016788 Not Cancer Driver No 84 0.457 0 0 0.0 0
DUSP23_ENST00000368109 DUSP23 Q9BVJ7 Dual specificity protein phosphatase 23 chr1 GO:0016788 Not Cancer Driver No 6 0.04 13 1 0.077 0
DUSP26 DUSP26 Q9BV47 Dual specificity protein phosphatase 26 chr8 GO:0016788 Not Cancer Driver No 56 0.265 14 6 0.429 0
DUSP27_ENST00000271385 STYXL2 Q5VZP5 Serine/threonine/tyrosine-interacting-like protein 2 chr1 GO:0016788 Not Cancer Driver No 330 0.285 864 257 0.297 0
DUSP28_ENST00000343217 DUSP28 Q4G0W2 Dual specificity phosphatase 28 chr2 GO:0016788 Not Cancer Driver No 11 0.062 55 4 0.073 0
DUSP3 DUSP3 P51452 Dual specificity protein phosphatase 3 chr17 GO:0016788 Not Cancer Driver No 21 0.114 4 1 0.25 0
DUSP4 DUSP4 Q13115 Dual specificity protein phosphatase 4 chr8 GO:0016788 Not Cancer Driver No 43 0.109 63 9 0.143 0
DUSP5 DUSP5 Q16690 Dual specificity protein phosphatase 5 chr10 GO:0016788 Not Cancer Driver No 58 0.151 36 4 0.111 0
DUSP6 DUSP6 Q16828 Dual specificity protein phosphatase 6 chr12 GO:0016788 Not Cancer Driver No 43 0.113 39 3 0.077 4
DUSP7 DUSP7 Q16829 Dual specificity protein phosphatase 7 chr3 GO:0016788 Not Cancer Driver No 40 0.095 139 5 0.036 0
DUSP8_ENST00000331588 DUSP8 Q13202 Dual specificity protein phosphatase 8 chr11 GO:0016788 Not Cancer Driver No 40 0.064 338 11 0.033 0
DUSP9 DUSP9 Q99956 Dual specificity protein phosphatase 9 chrX GO:0016788 Not Cancer Driver No 40 0.104 109 12 0.11 0
EDC3 EDC3 Q96F86 Enhancer of mRNA-decapping protein 3 chr15 GO:0016788 Not Cancer Driver No 43 0.085 185 22 0.119 1
EDNRA EDNRA P25101 Endothelin-1 receptor chr4 GO:0016788 Not Cancer Driver No 62 0.145 21 6 0.286 2
ELAC1 ELAC1 Q9H777 Zinc phosphodiesterase ELAC protein 1 chr18 GO:0016788 Not Cancer Driver No 40 0.11 47 4 0.085 0
ELAC2 ELAC2 Q9BQ52 Zinc phosphodiesterase ELAC protein 2 chr17 GO:0016788 Not Cancer Driver No 86 0.104 208 30 0.144 10
ENDOG ENDOG Q14249 Endonuclease G, mitochondrial chr9 GO:0016788 Not Cancer Driver No 11 0.037 61 1 0.016 0
ENDOV ENDOV Q8N8Q3 Endonuclease V chr17 GO:0016788 Not Cancer Driver No 28 0.099 43 3 0.07 0
ENOPH1 ENOPH1 Q9UHY7 Enolase-phosphatase E1 chr4 GO:0016788 Not Cancer Driver No 35 0.134 14 2 0.143 0
ENPP1 ENPP1 P22413 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 chr6 GO:0016788 Not Cancer Driver No 148 0.16 101 5 0.05 33
ENPP2_ENST00000075322 ENPP2 Q13822 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 chr8 GO:0016788 Not Cancer Driver No 168 0.195 81 16 0.198 0
ENPP3_ENST00000357639 ENPP3 O14638 Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 chr6 GO:0016788 Not Cancer Driver No 146 0.167 57 12 0.211 0
ENPP6 ENPP6 Q6UWR7 Glycerophosphocholine cholinephosphodiesterase ENPP6 chr4 GO:0016788 Not Cancer Driver No 88 0.2 7 1 0.143 0
ENPP7 ENPP7 Q6UWV6 Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 chr17 GO:0016788 Not Cancer Driver No 102 0.223 65 19 0.292 0
ENTPD6 ENTPD6 O75354 Ectonucleoside triphosphate diphosphohydrolase 6 chr20 GO:0016788 Not Cancer Driver No 68 0.14 41 6 0.146 0
EPHX2 EPHX2 P34913 Bifunctional epoxide hydrolase 2 chr8 GO:0016788 Not Cancer Driver No 78 0.141 26 3 0.115 0
ERCC1_ENST00000589165 ERCC1 P07992 DNA excision repair protein ERCC-1 chr19 GO:0016788 Not Cancer Driver No 42 0.141 105 14 0.133 1
ERCC4 ERCC4 Q92889 DNA repair endonuclease XPF chr16 GO:0016788 Census Yes 120 0.131 225 27 0.12 15
ESD ESD P10768 S-formylglutathione hydrolase chr13 GO:0016788 Not Cancer Driver No 33 0.117 4 0 0.0 0
ETHE1 ETHE1 O95571 Persulfide dioxygenase ETHE1, mitochondrial chr19 GO:0016788 Not Cancer Driver No 21 0.083 6 0 0.0 9
EXD2 EXD2 Q9NVH0 Exonuclease 3'-5' domain-containing protein 2 chr14 GO:0016788 Not Cancer Driver No 58 0.093 176 15 0.085 0
EXO1_ENST00000348581 EXO1 Q9UQ84 Exonuclease 1 chr1 GO:0016788 Not Cancer Driver No 123 0.145 472 76 0.161 0
EXO5_ENST00000358527 EXO5 Q9H790 Exonuclease V chr1 GO:0016788 Not Cancer Driver No 39 0.105 36 3 0.083 0
EXOG EXOG Q9Y2C4 Nuclease EXOG, mitochondrial chr3 GO:0016788 Not Cancer Driver No 42 0.114 52 1 0.019 0
EXOSC1 EXOSC1 Q9Y3B2 Exosome complex component CSL4 chr10 GO:0016788 Not Cancer Driver No 14 0.072 14 2 0.143 1
EXOSC10 EXOSC10 Q01780 Exosome component 10 chr1 GO:0016788 Not Cancer Driver No 87 0.098 375 35 0.093 0
EXOSC2 EXOSC2 Q13868 Exosome complex component RRP4 chr9 GO:0016788 Not Cancer Driver No 21 0.072 47 6 0.128 2
EXOSC3 EXOSC3 Q9NQT5 Exosome complex component RRP40 chr9 GO:0016788 Not Cancer Driver No 18 0.065 54 2 0.037 4
EXOSC4 EXOSC4 Q9NPD3 Exosome complex component RRP41 chr8 GO:0016788 Not Cancer Driver No 34 0.139 23 0 0.0 0
EXOSC5 EXOSC5 Q9NQT4 Exosome complex component RRP46 chr19 GO:0016788 Not Cancer Driver No 43 0.183 31 3 0.097 0
EXOSC6 EXOSC6 Q5RKV6 Exosome complex component MTR3 chr16 GO:0016788 Not Cancer Driver No 3 0.011 102 0 0.0 0
EXOSC7 EXOSC7 Q15024 Exosome complex component RRP42 chr3 GO:0016788 Not Cancer Driver No 41 0.141 8 1 0.125 0
EXOSC8 EXOSC8 Q96B26 Exosome complex component RRP43 chr13 GO:0016788 Not Cancer Driver No 20 0.072 28 1 0.036 2
EXOSC9_ENST00000243498 EXOSC9 Q06265 Exosome complex component RRP45 chr4 GO:0016788 Not Cancer Driver No 58 0.132 154 18 0.117 1
F2RL2 F2RL2 O00254 Proteinase-activated receptor 3 chr5 GO:0016788 Not Cancer Driver No 54 0.144 0 0 0.0 0
FAM83B FAM83B Q5T0W9 Protein FAM83B chr6 GO:0016788 Not Cancer Driver No 314 0.311 684 219 0.32 0
FAN1 FAN1 Q9Y2M0 Fanconi-associated nuclease 1 chr15 GO:0016788 Not Cancer Driver No 124 0.122 212 27 0.127 4
FASN FASN P49327 Fatty acid synthase chr17 GO:0016788 Not Cancer Driver No 291 0.116 309 42 0.136 0
FBP1_ENST00000375326 FBP1 P09467 Fructose-1,6-bisphosphatase 1 chr9 GO:0016788 Not Cancer Driver No 33 0.098 19 0 0.0 4
FBP2 FBP2 O00757 Fructose-1,6-bisphosphatase isozyme 2 chr9 GO:0016788 Not Cancer Driver No 54 0.159 15 3 0.2 0
FEN1 FEN1 P39748 Flap endonuclease 1 chr11 GO:0016788 Census Yes 35 0.092 111 11 0.099 0
FICD FICD Q9BVA6 Protein adenylyltransferase FICD chr12 GO:0016788 Not Cancer Driver No 46 0.1 42 3 0.071 0
FIG4 FIG4 Q92562 Polyphosphoinositide phosphatase chr6 GO:0016788 Not Cancer Driver No 114 0.126 177 26 0.147 7
G6PC G6PC1 P35575 Glucose-6-phosphatase catalytic subunit 1 chr17 GO:0016788 Not Cancer Driver No 67 0.188 0 0 0.0 54
G6PC2 G6PC2 Q9NQR9 Glucose-6-phosphatase 2 chr2 GO:0016788 Not Cancer Driver No 68 0.192 0 0 0.0 0
G6PC3 G6PC3 Q9BUM1 Glucose-6-phosphatase 3 chr17 GO:0016788 Not Cancer Driver No 21 0.061 2 0 0.0 21
GALNS GALNS P34059 N-acetylgalactosamine-6-sulfatase chr16 GO:0016788 Not Cancer Driver No 65 0.125 37 3 0.081 126
GDE1 GDE1 Q9NZC3 Glycerophosphodiester phosphodiesterase 1 chr16 GO:0016788 Not Cancer Driver No 36 0.109 37 1 0.027 0
GDPD2_ENST00000374382 GDPD2 Q9HCC8 Glycerophosphoinositol inositolphosphodiesterase GDPD2 chrX GO:0016788 Not Cancer Driver No 96 0.178 43 15 0.349 0
GDPD4_ENST00000376217 GDPD4 Q6W3E5 Glycerophosphodiester phosphodiesterase domain-containing protein 4 chr11 GO:0016788 Not Cancer Driver No 89 0.143 114 8 0.07 0
GDPD5_ENST00000529721 GDPD5 Q8WTR4 Glycerophosphodiester phosphodiesterase domain-containing protein 5 chr11 GO:0016788 Not Cancer Driver No 74 0.122 65 11 0.169 0
GEN1_ENST00000381254 GEN1 Q17RS7 Flap endonuclease GEN homolog 1 chr2 GO:0016788 Not Cancer Driver No 109 0.12 339 52 0.153 0
GNS GNS P15586 N-acetylglucosamine-6-sulfatase chr12 GO:0016788 Not Cancer Driver No 48 0.087 22 0 0.0 3
GPCPD1 GPCPD1 Q9NPB8 Glycerophosphocholine phosphodiesterase GPCPD1 chr20 GO:0016788 Not Cancer Driver No 69 0.103 60 8 0.133 0
GPLD1 GPLD1 P80108 Phosphatidylinositol-glycan-specific phospholipase D chr6 GO:0016788 Not Cancer Driver No 153 0.182 36 9 0.25 0
H6PD_ENST00000377403 H6PD O95479 GDH/6PGL endoplasmic bifunctional protein chr1 GO:0016788 Not Cancer Driver No 96 0.121 39 3 0.077 2
HAGH HAGH Q16775 Hydroxyacylglutathione hydrolase, mitochondrial chr16 GO:0016788 Not Cancer Driver No 26 0.084 41 1 0.024 0
HAGHL_ENST00000341413 HAGHL Q6PII5 Hydroxyacylglutathione hydrolase-like protein chr16 GO:0016788 Not Cancer Driver No 17 0.059 26 3 0.115 0
HDDC2 HDDC2 Q7Z4H3 5'-deoxynucleotidase HDDC2 chr6 GO:0016788 Not Cancer Driver No 26 0.127 74 7 0.095 0
HDDC3_ENST00000646620 HDDC3 Q8N4P3 Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1 chr15 GO:0016788 Not Cancer Driver No 13 0.073 76 9 0.118 0
HIBCH HIBCH Q6NVY1 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial chr2 GO:0016788 Not Cancer Driver No 42 0.109 26 0 0.0 1
HMOX1 HMOX1 P09601 Heme oxygenase 1 chr22 GO:0016788 Not Cancer Driver No 46 0.16 81 13 0.16 0
HRASLS2 PLAAT2 Q9NWW9 Phospholipase A and acyltransferase 2 chr11 GO:0016788 Not Cancer Driver No 24 0.148 16 2 0.125 0
HRASLS5 PLAAT5 Q96KN8 Phospholipase A and acyltransferase 5 chr11 GO:0016788 Not Cancer Driver No 41 0.147 127 12 0.094 0
IARS IARS1 P41252 Isoleucine--tRNA ligase, cytoplasmic chr9 GO:0016788 Not Cancer Driver No 130 0.103 28 4 0.143 4
IARS2 IARS2 Q9NSE4 Isoleucine--tRNA ligase, mitochondrial chr1 GO:0016788 Not Cancer Driver No 149 0.147 145 22 0.152 0
IDS IDS P22304 Iduronate 2-sulfatase chrX GO:0016788 Not Cancer Driver No 91 0.165 85 13 0.153 126
IMPA1_ENST00000256108 IMPA1 P29218 Inositol monophosphatase 1 chr8 GO:0016788 Not Cancer Driver No 36 0.13 3 0 0.0 0
IMPA2 IMPA2 O14732 Inositol monophosphatase 2 chr18 GO:0016788 Not Cancer Driver No 44 0.153 21 1 0.048 0
IMPAD1 BPNT2 Q9NX62 Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase chr8 GO:0016788 Not Cancer Driver No 45 0.125 86 10 0.116 2
INPP1 INPP1 P49441 Inositol polyphosphate 1-phosphatase chr2 GO:0016788 Not Cancer Driver No 44 0.11 23 1 0.043 0
INPP4A INPP4A Q96PE3 Inositol polyphosphate-4-phosphatase type I A chr2 GO:0016788 Not Cancer Driver No 114 0.117 153 20 0.131 0
INPP4B_ENST00000513000 INPP4B O15327 Inositol polyphosphate 4-phosphatase type II chr4 GO:0016788 Not Cancer Driver No 145 0.157 191 36 0.188 0
INPP5A INPP5A Q14642 Inositol polyphosphate-5-phosphatase A chr10 GO:0016788 Not Cancer Driver No 59 0.143 7 4 0.571 0
INPP5B_ENST00000373026 INPP5B P32019 Type II inositol 1,4,5-trisphosphate 5-phosphatase chr1 GO:0016788 Not Cancer Driver No 108 0.109 114 11 0.096 0
INPP5D INPP5D Q92835 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 chr2 GO:0016788 Not Cancer Driver No 176 0.148 578 90 0.156 0
INPP5E INPP5E Q9NRR6 Phosphatidylinositol polyphosphate 5-phosphatase type IV chr9 GO:0016788 Not Cancer Driver No 43 0.067 272 16 0.059 15
INPP5F INPP5F Q9Y2H2 Phosphatidylinositide phosphatase SAC2 chr10 GO:0016788 Not Cancer Driver No 138 0.122 394 45 0.114 0
INPP5J INPP5J Q15735 Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A chr22 GO:0016788 Not Cancer Driver No 102 0.101 629 42 0.067 0
INPP5K INPP5K Q9BT40 Inositol polyphosphate 5-phosphatase K chr17 GO:0016788 Not Cancer Driver No 42 0.094 34 2 0.059 7
INPPL1 INPPL1 O15357 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 chr11 GO:0016788 Not Cancer Driver No 174 0.138 566 76 0.134 4
ISG20 ISG20 Q96AZ6 Interferon-stimulated gene 20 kDa protein chr15 GO:0016788 Not Cancer Driver No 20 0.11 6 0 0.0 0
KIAA0391 PRORP O15091 Mitochondrial ribonuclease P catalytic subunit chr14 GO:0016788 Not Cancer Driver No 62 0.106 60 12 0.2 0
LARS LARS1 Q9P2J5 Leucine--tRNA ligase, cytoplasmic chr5 GO:0016788 Not Cancer Driver No 133 0.113 97 10 0.103 1
LARS2_ENST00000645846 LARS2 Q15031 Leucine--tRNA ligase, mitochondrial chr3 GO:0016788 Not Cancer Driver No 74 0.082 80 8 0.1 3
LCAT LCAT P04180 Phosphatidylcholine-sterol acyltransferase chr16 GO:0016788 Not Cancer Driver No 43 0.098 28 2 0.071 34
LIPA LIPA P38571 Lysosomal acid lipase/cholesteryl ester hydrolase chr10 GO:0016788 Not Cancer Driver No 44 0.11 12 1 0.083 4
LIPC_ENST00000356113 LIPC P11150 Hepatic triacylglycerol lipase chr15 GO:0016788 Not Cancer Driver No 91 0.182 17 3 0.176 2
LIPE LIPE Q05469 Hormone-sensitive lipase chr19 GO:0016788 Not Cancer Driver No 123 0.114 496 65 0.131 0
LIPG LIPG Q9Y5X9 Endothelial lipase chr18 GO:0016788 Not Cancer Driver No 90 0.18 59 7 0.119 0
LIPH LIPH Q8WWY8 Lipase member H chr3 GO:0016788 Not Cancer Driver No 71 0.157 32 8 0.25 2
LIPI_ENST00000536861 LIPI Q6XZB0 Lipase member I chr21 GO:0016788 Not Cancer Driver No 142 0.309 5 0 0.0 1
LIPJ LIPJ Q5W064 Lipase member J chr10 GO:0016788 Not Cancer Driver No 45 0.123 0 0 0.0 0
LIPK LIPK Q5VXJ0 Lipase member K chr10 GO:0016788 Not Cancer Driver No 44 0.11 0 0 0.0 0
LIPM LIPM Q5VYY2 Lipase member M chr10 GO:0016788 Not Cancer Driver No 18 0.043 13 0 0.0 0
LIPN LIPN Q5VXI9 Lipase member N chr10 GO:0016788 Not Cancer Driver No 53 0.133 8 1 0.125 0
LPIN1_ENST00000256720 LPIN1 Q14693 Phosphatidate phosphatase LPIN1 chr2 GO:0016788 Not Cancer Driver No 120 0.135 447 70 0.157 0
LPIN2 LPIN2 Q92539 Phosphatidate phosphatase LPIN2 chr18 GO:0016788 Not Cancer Driver No 113 0.126 455 56 0.123 1
LPIN3_ENST00000373257 LPIN3 Q9BQK8 Phosphatidate phosphatase LPIN3 chr20 GO:0016788 Not Cancer Driver No 91 0.107 472 50 0.106 0
LPL LPL P06858 Lipoprotein lipase chr8 GO:0016788 Not Cancer Driver No 94 0.198 23 3 0.13 70
LYPLA1 LYPLA1 O75608 Acyl-protein thioesterase 1 chr8 GO:0016788 Not Cancer Driver No 19 0.083 12 2 0.167 0
LYPLA2 LYPLA2 O95372 Acyl-protein thioesterase 2 chr1 GO:0016788 Not Cancer Driver No 22 0.095 13 2 0.154 0
LYPLAL1 LYPLAL1 Q5VWZ2 Lysophospholipase-like protein 1 chr1 GO:0016788 Not Cancer Driver No 30 0.127 2 0 0.0 0
MBLAC2 MBLAC2 Q68D91 Acyl-coenzyme A thioesterase MBLAC2 chr5 GO:0016788 Not Cancer Driver No 16 0.057 1 0 0.0 0
MDP1 MDP1 Q86V88 Magnesium-dependent phosphatase 1 chr14 GO:0016788 Not Cancer Driver No 25 0.142 35 8 0.229 0
MEIOB_ENST00000397344 MEIOB Q8N635 Meiosis-specific with OB domain-containing protein chr16 GO:0016788 Not Cancer Driver No 37 0.084 21 2 0.095 1
MGME1 MGME1 Q9BQP7 Mitochondrial genome maintenance exonuclease 1 chr20 GO:0016788 Not Cancer Driver No 33 0.096 95 7 0.074 1
MINPP1 MINPP1 Q9UNW1 Multiple inositol polyphosphate phosphatase 1 chr10 GO:0016788 Not Cancer Driver No 52 0.107 46 2 0.043 2
MPPE1 MPPE1 Q53F39 Metallophosphoesterase 1 chr18 GO:0016788 Not Cancer Driver No 39 0.098 27 5 0.185 0
MRE11 MRE11 P49959 Double-strand break repair protein MRE11 chr11 GO:0016788 Not Cancer Driver No 84 0.119 292 35 0.12 1
MRPL44 MRPL44 Q9H9J2 39S ribosomal protein L44, mitochondrial chr2 GO:0016788 Not Cancer Driver No 37 0.111 45 2 0.044 1
MRPL58 MRPL58 Q14197 Peptidyl-tRNA hydrolase ICT1, mitochondrial chr17 GO:0016788 Not Cancer Driver No 28 0.136 105 13 0.124 0
MTM1 MTM1 Q13496 Myotubularin chrX GO:0016788 Not Cancer Driver No 112 0.186 79 9 0.114 57
MTMR10 MTMR10 Q9NXD2 Myotubularin-related protein 10 chr15 GO:0016788 Not Cancer Driver No 79 0.102 98 7 0.071 0
MTMR11 MTMR11 A4FU01 Myotubularin-related protein 11 chr1 GO:0016788 Not Cancer Driver No 108 0.152 147 17 0.116 0
MTMR12 MTMR12 Q9C0I1 Myotubularin-related protein 12 chr5 GO:0016788 Not Cancer Driver No 105 0.141 130 16 0.123 0
MTMR14 MTMR14 Q8NCE2 Myotubularin-related protein 14 chr3 GO:0016788 Not Cancer Driver No 58 0.089 150 8 0.053 2
MTMR1_ENST00000370390 MTMR1 Q13613 Myotubularin-related protein 1 chrX GO:0016788 Not Cancer Driver No 114 0.171 146 21 0.144 0
MTMR2 MTMR2 Q13614 Myotubularin-related protein 2 chr11 GO:0016788 Not Cancer Driver No 70 0.109 140 16 0.114 1
MTMR3 MTMR3 Q13615 Myotubularin-related protein 3 chr22 GO:0016788 Not Cancer Driver No 130 0.109 501 66 0.132 0
MTMR4 MTMR4 Q9NYA4 Myotubularin-related protein 4 chr17 GO:0016788 Not Cancer Driver No 147 0.123 474 59 0.124 0
MTMR6 MTMR6 Q9Y217 Myotubularin-related protein 6 chr13 GO:0016788 Not Cancer Driver No 87 0.14 68 16 0.235 0
MTMR7 MTMR7 Q9Y216 Myotubularin-related protein 7 chr8 GO:0016788 Not Cancer Driver No 98 0.148 160 26 0.163 0
MTMR8 MTMR8 Q96EF0 Myotubularin-related protein 8 chrX GO:0016788 Not Cancer Driver No 140 0.199 55 8 0.145 0
MTMR9 MTMR9 Q96QG7 Myotubularin-related protein 9 chr8 GO:0016788 Not Cancer Driver No 60 0.109 45 7 0.156 0
MUS81 MUS81 Q96NY9 Crossover junction endonuclease MUS81 chr11 GO:0016788 Not Cancer Driver No 67 0.122 232 38 0.164 0
MYH3 MYH3 P11055 Myosin-3 chr17 GO:0016788 Not Cancer Driver No 312 0.161 967 179 0.185 14
MYH6 MYH6 P13533 Myosin-6 chr14 GO:0016788 Not Cancer Driver No 392 0.202 1112 238 0.214 7
MYH8 MYH8 P13535 Myosin-8 chr17 GO:0016788 Not Cancer Driver No 498 0.257 1086 315 0.29 2
NANP NANP Q8TBE9 N-acylneuraminate-9-phosphatase chr20 GO:0016788 Not Cancer Driver No 18 0.073 4 0 0.0 0
NAPEPLD NAPEPLD Q6IQ20 N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D chr7 GO:0016788 Not Cancer Driver No 55 0.14 76 7 0.092 0
NDST1 NDST1 P52848 Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 chr5 GO:0016788 Not Cancer Driver No 117 0.133 22 1 0.045 4
NDST3 NDST3 O95803 Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3 chr4 GO:0016788 Not Cancer Driver No 186 0.213 9 1 0.111 0
NOCT NOCT Q9UK39 Nocturnin chr4 GO:0016788 Not Cancer Driver No 33 0.077 89 3 0.034 0
NOTUM NOTUM Q6P988 Palmitoleoyl-protein carboxylesterase NOTUM chr17 GO:0016788 Not Cancer Driver No 50 0.101 73 6 0.082 0
NT5C NT5C Q8TCD5 5'(3')-deoxyribonucleotidase, cytosolic type chr17 GO:0016788 Not Cancer Driver No 19 0.095 4 0 0.0 0
NT5C1A NT5C1A Q9BXI3 Cytosolic 5'-nucleotidase 1A chr1 GO:0016788 Not Cancer Driver No 86 0.234 95 16 0.168 0
NT5C2_ENST00000404739 NT5C2 P49902 Cytosolic purine 5'-nucleotidase chr10 GO:0016788 Census Yes 57 0.102 85 8 0.094 0
NUDT12 NUDT12 Q9BQG2 NAD-capped RNA hydrolase NUDT12 chr5 GO:0016788 Not Cancer Driver No 65 0.141 11 2 0.182 0
NUDT16L1 NUDT16L1 Q9BRJ7 Tudor-interacting repair regulator protein chr16 GO:0016788 Not Cancer Driver No 16 0.076 6 0 0.0 0
NUDT16_ENST00000521288 NUDT16 Q96DE0 U8 snoRNA-decapping enzyme chr3 GO:0016788 Not Cancer Driver No 29 0.149 8 1 0.125 0
NUDT7 NUDT7 P0C024 Peroxisomal coenzyme A diphosphatase NUDT7 chr16 GO:0016788 Not Cancer Driver No 45 0.189 42 4 0.095 0
OCRL OCRL Q01968 Inositol polyphosphate 5-phosphatase OCRL chrX GO:0016788 Not Cancer Driver No 151 0.168 126 24 0.19 41
OLAH_ENST00000378228 OLAH Q9NV23 S-acyl fatty acid synthase thioesterase, medium chain chr10 GO:0016788 Not Cancer Driver No 53 0.2 44 13 0.295 0
PAFAH1B2 PAFAH1B2 P68402 Platelet-activating factor acetylhydrolase IB subunit alpha2 chr11 GO:0016788 Census Yes 25 0.109 43 1 0.023 0
PAFAH1B3_ENST00000262890 PAFAH1B3 Q15102 Platelet-activating factor acetylhydrolase IB subunit alpha1 chr19 GO:0016788 Not Cancer Driver No 15 0.065 76 3 0.039 0
PAFAH2_ENST00000374284 PAFAH2 Q99487 Platelet-activating factor acetylhydrolase 2, cytoplasmic chr1 GO:0016788 Not Cancer Driver No 62 0.158 41 7 0.171 0
PAN2_ENST00000548043 PAN2 Q504Q3 PAN2-PAN3 deadenylation complex catalytic subunit PAN2 chr12 GO:0016788 Not Cancer Driver No 139 0.116 78 10 0.128 0
PAN3 PAN3 Q58A45 PAN2-PAN3 deadenylation complex subunit PAN3 chr13 GO:0016788 Not Cancer Driver No 104 0.117 323 35 0.108 0
PARN PARN O95453 Poly(A)-specific ribonuclease PARN chr16 GO:0016788 Not Cancer Driver No 71 0.111 197 22 0.112 2
PDE10A_ENST00000366882 PDE10A Q9Y233 cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A chr6 GO:0016788 Not Cancer Driver No 198 0.254 79 21 0.266 4
PDE12 PDE12 Q6L8Q7 2',5'-phosphodiesterase 12 chr3 GO:0016788 Not Cancer Driver No 59 0.097 129 8 0.062 0
PDE1A_ENST00000410103 PDE1A P54750 Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A chr2 GO:0016788 Not Cancer Driver No 157 0.293 61 7 0.115 0
PDE1B PDE1B Q01064 Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B chr12 GO:0016788 Not Cancer Driver No 114 0.213 132 30 0.227 0
PDE1C_ENST00000321453 PDE1C Q14123 Dual specificity Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C chr7 GO:0016788 Not Cancer Driver No 253 0.357 281 97 0.345 1
PDE2A PDE2A O00408 cGMP-dependent 3',5'-cyclic phosphodiesterase chr11 GO:0016788 Not Cancer Driver No 137 0.146 99 7 0.071 0
PDE3A PDE3A Q14432 cGMP-inhibited 3',5'-cyclic phosphodiesterase A chr12 GO:0016788 Not Cancer Driver No 274 0.24 527 114 0.216 6
PDE3B PDE3B Q13370 cGMP-inhibited 3',5'-cyclic phosphodiesterase B chr11 GO:0016788 Not Cancer Driver No 135 0.121 393 37 0.094 0
PDP1_ENST00000297598 PDP1 Q9P0J1 [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial chr8 GO:0016788 Not Cancer Driver No 64 0.119 96 9 0.094 0
PDP2 PDP2 Q9P2J9 [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial chr16 GO:0016788 Not Cancer Driver No 52 0.098 51 11 0.216 0
PDXP PDXP Q96GD0 Chronophin chr22 GO:0016788 Not Cancer Driver No 14 0.047 38 4 0.105 0
PFKFB1 PFKFB1 P16118 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 chrX GO:0016788 Not Cancer Driver No 81 0.172 48 11 0.229 0
PFKFB2 PFKFB2 O60825 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 chr1 GO:0016788 Not Cancer Driver No 68 0.135 97 18 0.186 0
PFKFB3_ENST00000379775 PFKFB3 Q16875 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 chr10 GO:0016788 Not Cancer Driver No 65 0.125 97 19 0.196 0
PFKFB4 PFKFB4 Q16877 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 chr3 GO:0016788 Not Cancer Driver No 71 0.151 44 3 0.068 0
PGAP1 PGAP1 Q75T13 GPI inositol-deacylase chr2 GO:0016788 Not Cancer Driver No 127 0.138 21 7 0.333 0
PGAP3 PGAP3 Q96FM1 Post-GPI attachment to proteins factor 3 chr17 GO:0016788 Not Cancer Driver No 37 0.116 0 0 0.0 3
PGLS PGLS O95336 6-phosphogluconolactonase chr19 GO:0016788 Not Cancer Driver No 20 0.078 36 4 0.111 0
PGP PGP A6NDG6 Glycerol-3-phosphate phosphatase chr16 GO:0016788 Not Cancer Driver No 10 0.031 21 0 0.0 0
PHOSPHO1_ENST00000310544 PHOSPHO1 Q8TCT1 Phosphoethanolamine/phosphocholine phosphatase chr17 GO:0016788 Not Cancer Driver No 14 0.052 18 0 0.0 0
PHOSPHO2_ENST00000616481 PHOSPHO2 Q8TCD6 Pyridoxal phosphate phosphatase PHOSPHO2 chr2 GO:0016788 Not Cancer Driver No 38 0.158 0 0 0.0 0
PHPT1 PHPT1 Q9NRX4 14 kDa phosphohistidine phosphatase chr9 GO:0016788 Not Cancer Driver No 13 0.104 6 0 0.0 0
PIKFYVE PIKFYVE Q9Y2I7 1-phosphatidylinositol 3-phosphate 5-kinase chr2 GO:0016788 Not Cancer Driver No 278 0.133 848 101 0.119 1
PIP4P1_ENST00000250489 PIP4P1 Q86T03 Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase chr14 GO:0016788 Not Cancer Driver No 36 0.13 78 4 0.051 0
PIP4P2 PIP4P2 Q8N4L2 Type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase chr8 GO:0016788 Not Cancer Driver No 41 0.16 46 4 0.087 0
PLA1A PLA1A Q53H76 Phospholipase A1 member A chr3 GO:0016788 Not Cancer Driver No 94 0.206 10 0 0.0 0
PLA2G10 PLA2G10 O15496 Group 10 secretory phospholipase A2 chr16 GO:0016788 Not Cancer Driver No 5 0.03 0 0 0.0 0
PLA2G12A PLA2G12A Q9BZM1 Group XIIA secretory phospholipase A2 chr4 GO:0016788 Not Cancer Driver No 18 0.095 0 0 0.0 0
PLA2G15 PLA2G15 Q8NCC3 Phospholipase A2 group XV chr16 GO:0016788 Not Cancer Driver No 61 0.148 11 3 0.273 0
PLA2G16 PLAAT3 P53816 Phospholipase A and acyltransferase 3 chr11 GO:0016788 Not Cancer Driver No 16 0.099 13 1 0.077 0
PLA2G1B PLA2G1B P04054 Phospholipase A2 chr12 GO:0016788 Not Cancer Driver No 17 0.115 0 0 0.0 0
PLA2G2A_ENST00000375111 PLA2G2A P14555 Phospholipase A2, membrane associated chr1 GO:0016788 Not Cancer Driver No 25 0.174 0 0 0.0 0
PLA2G2C_ENST00000429261 PLA2G2C Q5R387 Putative inactive group IIC secretory phospholipase A2 chr1 GO:0016788 Not Cancer Driver No 18 0.121 10 0 0.0 0
PLA2G2D PLA2G2D Q9UNK4 Group IID secretory phospholipase A2 chr1 GO:0016788 Not Cancer Driver No 27 0.186 0 0 0.0 0
PLA2G2E PLA2G2E Q9NZK7 Group IIE secretory phospholipase A2 chr1 GO:0016788 Not Cancer Driver No 33 0.232 0 0 0.0 0
PLA2G3 PLA2G3 Q9NZ20 Group 3 secretory phospholipase A2 chr22 GO:0016788 Not Cancer Driver No 115 0.226 175 39 0.223 0
PLA2G4A PLA2G4A P47712 Cytosolic phospholipase A2 chr1 GO:0016788 Not Cancer Driver No 149 0.199 129 28 0.217 1
PLA2G4B_ENST00000458483 PLA2G4B P0C869 Cytosolic phospholipase A2 beta chr15 GO:0016788 Not Cancer Driver No 88 0.113 144 18 0.125 0
PLA2G4C_ENST00000599921 PLA2G4C Q9UP65 Cytosolic phospholipase A2 gamma chr19 GO:0016788 Not Cancer Driver No 107 0.198 62 9 0.145 0
PLA2G4D PLA2G4D Q86XP0 Cytosolic phospholipase A2 delta chr15 GO:0016788 Not Cancer Driver No 115 0.141 172 17 0.099 0
PLA2G4E PLA2G4E Q3MJ16 Cytosolic phospholipase A2 epsilon chr15 GO:0016788 Not Cancer Driver No 71 0.082 123 6 0.049 0
PLA2G4F PLA2G4F Q68DD2 Cytosolic phospholipase A2 zeta chr15 GO:0016788 Not Cancer Driver No 121 0.143 106 6 0.057 0
PLA2G5 PLA2G5 P39877 Phospholipase A2 group V chr1 GO:0016788 Not Cancer Driver No 24 0.174 0 0 0.0 2
PLA2G6 PLA2G6 O60733 85/88 kDa calcium-independent phospholipase A2 chr22 GO:0016788 Not Cancer Driver No 108 0.134 148 23 0.155 11
PLA2G7 PLA2G7 Q13093 Platelet-activating factor acetylhydrolase chr6 GO:0016788 Not Cancer Driver No 70 0.159 27 7 0.259 2
PLB1 PLB1 Q6P1J6 Phospholipase B1, membrane-associated chr2 GO:0016788 Not Cancer Driver No 223 0.153 399 57 0.143 0
PLCB1 PLCB1 Q9NQ66 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 chr20 GO:0016788 Not Cancer Driver No 313 0.257 481 104 0.216 0
PLCB2 PLCB2 Q00722 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 chr15 GO:0016788 Not Cancer Driver No 161 0.136 495 51 0.103 0
PLCB3 PLCB3 Q01970 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 chr11 GO:0016788 Not Cancer Driver No 144 0.117 595 68 0.114 1
PLCB4_ENST00000278655 PLCB4 Q15147 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 chr20 GO:0016788 Compendium Yes 338 0.288 401 120 0.299 5
PLCD1_ENST00000334661 PLCD1 P51178 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 chr3 GO:0016788 Not Cancer Driver No 94 0.124 111 13 0.117 2
PLCD3 PLCD3 Q8N3E9 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 chr17 GO:0016788 Not Cancer Driver No 61 0.077 229 22 0.096 0
PLCD4_ENST00000417849 PLCD4 Q9BRC7 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 chr2 GO:0016788 Not Cancer Driver No 78 0.102 90 5 0.056 0
PLCE1 PLCE1 Q9P212 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 chr10 GO:0016788 Not Cancer Driver No 367 0.159 780 107 0.137 1
PLCG1_ENST00000373271 PLCG1 P19174 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 chr20 GO:0016788 Census, Compendium Yes 158 0.122 186 21 0.113 0
PLCG2 PLCG2 P16885 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 chr16 GO:0016788 Not Cancer Driver No 248 0.196 142 30 0.211 1
PLCH1 PLCH1 Q4KWH8 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 chr3 GO:0016788 Not Cancer Driver No 383 0.226 772 195 0.253 0
PLCH2 PLCH2 O75038 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2 chr1 GO:0016788 Not Cancer Driver No 145 0.102 786 71 0.09 0
PLCL1 PLCL1 Q15111 Inactive phospholipase C-like protein 1 chr2 GO:0016788 Not Cancer Driver No 258 0.236 205 33 0.161 0
PLCL2 PLCL2 Q9UPR0 Inactive phospholipase C-like protein 2 chr3 GO:0016788 Not Cancer Driver No 185 0.164 274 31 0.113 0
PLCZ1 PLCZ1 Q86YW0 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 chr12 GO:0016788 Not Cancer Driver No 151 0.248 37 20 0.541 1
PLD1 PLD1 Q13393 Phospholipase D1 chr3 GO:0016788 Not Cancer Driver No 181 0.169 133 32 0.241 1
PLD2 PLD2 O14939 Phospholipase D2 chr17 GO:0016788 Not Cancer Driver No 107 0.115 97 8 0.082 0
PLD3_ENST00000409735 PLD3 Q8IV08 5'-3' exonuclease PLD3 chr19 GO:0016788 Not Cancer Driver No 70 0.143 62 7 0.113 0
PLD4_ENST00000392593 PLD4 Q96BZ4 5'-3' exonuclease PLD4 chr14 GO:0016788 Not Cancer Driver No 46 0.091 76 10 0.132 0
PLD6 PLD6 Q8N2A8 Mitochondrial cardiolipin hydrolase chr17 GO:0016788 Not Cancer Driver No 27 0.107 24 6 0.25 0
PLPP1_ENST00000307259 PLPP1 O14494 Phospholipid phosphatase 1 chr5 GO:0016788 Not Cancer Driver No 28 0.099 27 1 0.037 0
PLPP2_ENST00000434325 PLPP2 O43688 Phospholipid phosphatase 2 chr19 GO:0016788 Not Cancer Driver No 47 0.163 0 0 0.0 0
PLPP3 PLPP3 O14495 Phospholipid phosphatase 3 chr1 GO:0016788 Not Cancer Driver No 48 0.154 10 1 0.1 0
PLPP4 PLPP4 Q5VZY2 Phospholipid phosphatase 4 chr10 GO:0016788 Not Cancer Driver No 59 0.218 14 1 0.071 0
PLPP5 PLPP5 Q8NEB5 Phospholipid phosphatase 5 chr8 GO:0016788 Not Cancer Driver No 22 0.083 0 0 0.0 0
PLPP6 PLPP6 Q8IY26 Polyisoprenoid diphosphate/phosphate phosphohydrolase PLPP6 chr9 GO:0016788 Not Cancer Driver No 16 0.054 80 0 0.0 0
PLPP7 PLPP7 Q8NBV4 Inactive phospholipid phosphatase 7 chr9 GO:0016788 Not Cancer Driver No 45 0.166 72 9 0.125 0
PLPPR1_ENST00000395056 PLPPR1 Q8TBJ4 Phospholipid phosphatase-related protein type 1 chr9 GO:0016788 Not Cancer Driver No 78 0.24 34 16 0.471 0
PLPPR2_ENST00000251473 PLPPR2 Q96GM1 Phospholipid phosphatase-related protein type 2 chr19 GO:0016788 Not Cancer Driver No 55 0.16 55 7 0.127 0
PLPPR3_ENST00000520876 PLPPR3 Q6T4P5 Phospholipid phosphatase-related protein type 3 chr19 GO:0016788 Not Cancer Driver No 50 0.07 431 8 0.019 0
PLPPR4 PLPPR4 Q7Z2D5 Phospholipid phosphatase-related protein type 4 chr1 GO:0016788 Not Cancer Driver No 177 0.232 457 118 0.258 0
PLPPR5 PLPPR5 Q32ZL2 Phospholipid phosphatase-related protein type 5 chr1 GO:0016788 Not Cancer Driver No 74 0.231 0 0 0.0 0
PNKD PNKD Q8N490 Probable hydrolase PNKD chr2 GO:0016788 Not Cancer Driver No 52 0.135 160 25 0.156 2
PNKP PNKP Q96T60 Bifunctional polynucleotide phosphatase/kinase chr19 GO:0016788 Not Cancer Driver No 53 0.102 177 23 0.13 4
PNLDC1_ENST00000610273 PNLDC1 Q8NA58 Poly(A)-specific ribonuclease PNLDC1 chr6 GO:0016788 Not Cancer Driver No 105 0.202 6 0 0.0 1
PNLIP PNLIP P16233 Pancreatic triacylglycerol lipase chr10 GO:0016788 Not Cancer Driver No 124 0.267 32 11 0.344 1
PNLIPRP2 PNLIPRP2 P54317 Pancreatic lipase-related protein 2 chr10 GO:0016788 Not Cancer Driver No 75 0.16 28 2 0.071 0
PNPLA2 PNPLA2 Q96AD5 Patatin-like phospholipase domain-containing protein 2 chr11 GO:0016788 Not Cancer Driver No 35 0.069 101 4 0.04 1
PNPLA3 PNPLA3 Q9NST1 1-acylglycerol-3-phosphate O-acyltransferase PNPLA3 chr22 GO:0016788 Not Cancer Driver No 54 0.112 33 7 0.212 0
PNPLA4_ENST00000444736 PNPLA4 P41247 Patatin-like phospholipase domain-containing protein 4 chrX GO:0016788 Not Cancer Driver No 41 0.162 3 0 0.0 0
PNPLA6 PNPLA6 Q8IY17 Patatin-like phospholipase domain-containing protein 6 chr19 GO:0016788 Not Cancer Driver No 171 0.124 367 49 0.134 18
PNPLA7_ENST00000277531 PNPLA7 Q6ZV29 Patatin-like phospholipase domain-containing protein 7 chr9 GO:0016788 Not Cancer Driver No 180 0.137 283 35 0.124 0
PNPLA8 PNPLA8 Q9NP80 Calcium-independent phospholipase A2-gamma chr7 GO:0016788 Not Cancer Driver No 94 0.12 140 18 0.129 0
POLE POLE Q07864 DNA polymerase epsilon catalytic subunit A chr12 GO:0016788 Census, Compendium Yes 409 0.179 239 44 0.184 3
PON1 PON1 P27169 Serum paraoxonase/arylesterase 1 chr7 GO:0016788 Not Cancer Driver No 80 0.225 10 9 0.9 0
PON2 PON2 Q15165 Serum paraoxonase/arylesterase 2 chr7 GO:0016788 Not Cancer Driver No 46 0.13 13 3 0.231 0
PON3 PON3 Q15166 Serum paraoxonase/lactonase 3 chr7 GO:0016788 Not Cancer Driver No 69 0.195 32 6 0.188 0
POP1_ENST00000349693 POP1 Q99575 Ribonucleases P/MRP protein subunit POP1 chr8 GO:0016788 Not Cancer Driver No 161 0.157 495 75 0.152 3
POP4 POP4 O95707 Ribonuclease P protein subunit p29 chr19 GO:0016788 Not Cancer Driver No 25 0.114 53 9 0.17 0
POP5 POP5 Q969H6 Ribonuclease P/MRP protein subunit POP5 chr12 GO:0016788 Not Cancer Driver No 17 0.104 9 2 0.222 0
POP7 POP7 O75817 Ribonuclease P protein subunit p20 chr7 GO:0016788 Not Cancer Driver No 20 0.143 59 13 0.22 0
PPM1A_ENST00000395076 PPM1A P35813 Protein phosphatase 1A chr14 GO:0016788 Not Cancer Driver No 60 0.157 134 24 0.179 0
PPM1F PPM1F P49593 Protein phosphatase 1F chr22 GO:0016788 Not Cancer Driver No 53 0.117 242 24 0.099 0
PPME1_ENST00000328257 PPME1 Q9Y570 Protein phosphatase methylesterase 1 chr11 GO:0016788 Not Cancer Driver No 35 0.091 146 9 0.062 0
PPP1CB_ENST00000358506 PPP1CB P62140 Serine/threonine-protein phosphatase PP1-beta catalytic subunit chr2 GO:0016788 Not Cancer Driver No 47 0.144 25 5 0.2 5
PPP1R3B PPP1R3B Q86XI6 Protein phosphatase 1 regulatory subunit 3B chr8 GO:0016788 Not Cancer Driver No 36 0.126 19 2 0.105 0
PPP1R3E PPP1R3E Q9H7J1 Protein phosphatase 1 regulatory subunit 3E chr14 GO:0016788 Not Cancer Driver No 1 0.004 182 0 0.0 0
PPP1R8 PPP1R8 Q12972 Nuclear inhibitor of protein phosphatase 1 chr1 GO:0016788 Not Cancer Driver No 24 0.068 251 19 0.076 0
PPP3CA PPP3CA Q08209 Protein phosphatase 3 catalytic subunit alpha chr4 GO:0016788 Compendium Yes 85 0.163 140 27 0.193 7
PPP3CB_ENST00000360663 PPP3CB P16298 Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform chr10 GO:0016788 Not Cancer Driver No 67 0.128 139 18 0.129 0
PPP3CC_ENST00000240139 PPP3CC P48454 Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform chr8 GO:0016788 Not Cancer Driver No 47 0.092 91 7 0.077 0
PPP3R1 PPP3R1 P63098 Calcineurin subunit B type 1 chr2 GO:0016788 Not Cancer Driver No 19 0.112 1 0 0.0 0
PPT1 PPT1 P50897 Palmitoyl-protein thioesterase 1 chr1 GO:0016788 Not Cancer Driver No 37 0.121 0 0 0.0 23
PPT2_ENST00000395523 PPT2 Q9UMR5 Lysosomal thioesterase PPT2 chr6 GO:0016788 Compendium Yes 45 0.149 0 0 0.0 0
PRDX6 PRDX6 P30041 Peroxiredoxin-6 chr1 GO:0016788 Not Cancer Driver No 46 0.205 13 4 0.308 0
PSPH_ENST00000275605 PSPH P78330 Phosphoserine phosphatase chr7 GO:0016788 Not Cancer Driver No 44 0.196 21 6 0.286 3
PTEN PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 GO:0016788 Census, Compendium Yes 505 1.253 76 4 0.053 41
PTER_ENST00000535784 PTER Q96BW5 Phosphotriesterase-related protein chr10 GO:0016788 Not Cancer Driver No 55 0.158 28 6 0.214 0
PTP4A1 PTP4A1 Q93096 Protein tyrosine phosphatase type IVA 1 chr6 GO:0016788 Not Cancer Driver No 21 0.121 2 0 0.0 0
PTP4A2 PTP4A2 Q12974 Protein tyrosine phosphatase type IVA 2 chr1 GO:0016788 Not Cancer Driver No 14 0.084 3 1 0.333 0
PTP4A3_ENST00000521578 PTP4A3 O75365 Protein tyrosine phosphatase type IVA 3 chr8 GO:0016788 Not Cancer Driver No 30 0.173 3 0 0.0 0
PTPDC1_ENST00000375360 PTPDC1 A2A3K4 Protein tyrosine phosphatase domain-containing protein 1 chr9 GO:0016788 Not Cancer Driver No 85 0.113 301 26 0.086 0
PTPMT1 PTPMT1 Q8WUK0 Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 chr11 GO:0016788 Not Cancer Driver No 16 0.08 0 0 0.0 0
PTPN11_ENST00000351677 PTPN11 Q06124 Tyrosine-protein phosphatase non-receptor type 11 chr12 GO:0016788 Census, Compendium Yes 129 0.218 260 38 0.146 60
PTPN12 PTPN12 Q05209 Tyrosine-protein phosphatase non-receptor type 12 chr7 GO:0016788 Not Cancer Driver No 102 0.131 516 60 0.116 0
PTPN18 PTPN18 Q99952 Tyrosine-protein phosphatase non-receptor type 18 chr2 GO:0016788 Not Cancer Driver No 51 0.111 138 8 0.058 0
PTPN22 PTPN22 Q9Y2R2 Tyrosine-protein phosphatase non-receptor type 22 chr1 GO:0016788 Not Cancer Driver No 141 0.175 364 62 0.17 4
PTPN4 PTPN4 P29074 Tyrosine-protein phosphatase non-receptor type 4 chr2 GO:0016788 Not Cancer Driver No 132 0.143 263 32 0.122 0
PTPN6_ENST00000318974 PTPN6 P29350 Tyrosine-protein phosphatase non-receptor type 6 chr12 GO:0016788 Census, Compendium Yes 73 0.123 192 25 0.13 0
PTPN9 PTPN9 P43378 Tyrosine-protein phosphatase non-receptor type 9 chr15 GO:0016788 Not Cancer Driver No 77 0.13 78 5 0.064 0
PTPRA_ENST00000399903 PTPRA P18433 Receptor-type tyrosine-protein phosphatase alpha chr20 GO:0016788 Not Cancer Driver No 98 0.122 210 21 0.1 0
PTPRB_ENST00000261266 PTPRB P23467 Receptor-type tyrosine-protein phosphatase beta chr12 GO:0016788 Census, Compendium Yes 425 0.213 302 65 0.215 0
PTPRC PTPRC P08575 Receptor-type tyrosine-protein phosphatase C chr1 GO:0016788 Census, Compendium Yes 315 0.241 462 107 0.232 0
PTPRD PTPRD P23468 Receptor-type tyrosine-protein phosphatase delta chr9 GO:0016788 Census, Compendium Yes 577 0.302 747 219 0.293 0
PTPRE PTPRE P23469 Receptor-type tyrosine-protein phosphatase epsilon chr10 GO:0016788 Not Cancer Driver No 122 0.174 97 13 0.134 0
PTPRF PTPRF P10586 Receptor-type tyrosine-protein phosphatase F chr1 GO:0016788 Not Cancer Driver No 268 0.141 696 96 0.138 0
PTPRG PTPRG P23470 Receptor-type tyrosine-protein phosphatase gamma chr3 GO:0016788 Not Cancer Driver No 212 0.147 465 61 0.131 0
PTPRH PTPRH Q9HD43 Receptor-type tyrosine-protein phosphatase H chr19 GO:0016788 Not Cancer Driver No 228 0.204 474 74 0.156 0
PTPRK_ENST00000368215 PTPRK Q15262 Receptor-type tyrosine-protein phosphatase kappa chr6 GO:0016788 Census, Compendium Yes 292 0.203 302 57 0.189 0
PTPRM_ENST00000332175 PTPRM P28827 Receptor-type tyrosine-protein phosphatase mu chr18 GO:0016788 Not Cancer Driver No 256 0.176 365 60 0.164 0
PTPRN2 PTPRN2 Q92932 Receptor-type tyrosine-protein phosphatase N2 chr7 GO:0016788 Not Cancer Driver No 274 0.27 580 169 0.291 0
PTPRO PTPRO Q16827 Receptor-type tyrosine-protein phosphatase O chr12 GO:0016788 Not Cancer Driver No 204 0.168 137 34 0.248 0
PTPRR PTPRR Q15256 Receptor-type tyrosine-protein phosphatase R chr12 GO:0016788 Not Cancer Driver No 172 0.262 73 28 0.384 0
PTPRT_ENST00000373187 PTPRT O14522 Receptor-type tyrosine-protein phosphatase T chr20 GO:0016788 Census, Compendium Yes 535 0.371 299 125 0.418 0
PTPRU PTPRU Q92729 Receptor-type tyrosine-protein phosphatase U chr1 GO:0016788 Not Cancer Driver No 248 0.172 325 64 0.197 0
PTPRZ1 PTPRZ1 P23471 Receptor-type tyrosine-protein phosphatase zeta chr7 GO:0016788 Not Cancer Driver No 480 0.207 978 216 0.221 0
PTRH1 PTRH1 Q86Y79 Probable peptidyl-tRNA hydrolase chr9 GO:0016788 Not Cancer Driver No 18 0.084 52 6 0.115 0
PTRH2_ENST00000470557 PTRH2 Q9Y3E5 Peptidyl-tRNA hydrolase 2, mitochondrial chr17 GO:0016788 Not Cancer Driver No 14 0.078 19 2 0.105 1
PTRHD1 PTRHD1 Q6GMV3 Putative peptidyl-tRNA hydrolase PTRHD1 chr2 GO:0016788 Not Cancer Driver No 12 0.086 22 2 0.091 0
PUDP_ENST00000381077 PUDP Q08623 Pseudouridine-5'-phosphatase chrX GO:0016788 Not Cancer Driver No 45 0.197 9 1 0.111 0
RAD1 RAD1 O60671 Cell cycle checkpoint protein RAD1 chr5 GO:0016788 Not Cancer Driver No 29 0.103 4 1 0.25 0
RAD50 RAD50 Q92878 DNA repair protein RAD50 chr5 GO:0016788 Not Cancer Driver No 157 0.12 730 84 0.115 0
RAD51C RAD51C O43502 DNA repair protein RAD51 homolog 3 chr17 GO:0016788 Not Cancer Driver No 47 0.125 18 2 0.111 6
RAD9A RAD9A Q99638 Cell cycle checkpoint control protein RAD9A chr11 GO:0016788 Not Cancer Driver No 34 0.087 135 7 0.052 0
RAG1 RAG1 P15918 V(D)J recombination-activating protein 1 chr11 GO:0016788 Not Cancer Driver No 204 0.196 208 43 0.207 36
RARRES3 PLAAT4 Q9UL19 Phospholipase A and acyltransferase 4 chr11 GO:0016788 Not Cancer Driver No 25 0.152 7 1 0.143 0
RBBP8_ENST00000327155 RBBP8 Q99708 DNA endonuclease RBBP8 chr18 GO:0016788 Not Cancer Driver No 99 0.11 750 76 0.101 1
RGN RGN Q15493 Regucalcin chrX GO:0016788 Not Cancer Driver No 38 0.127 14 3 0.214 0
RIDA RIDA P52758 2-iminobutanoate/2-iminopropanoate deaminase chr8 GO:0016788 Not Cancer Driver No 20 0.146 3 0 0.0 0
RNASE1_ENST00000412779 RNASE1 P07998 Ribonuclease pancreatic chr14 GO:0016788 Not Cancer Driver No 17 0.109 49 11 0.224 0
RNASE2 RNASE2 P10153 Non-secretory ribonuclease chr14 GO:0016788 Not Cancer Driver No 30 0.186 20 4 0.2 0
RNASE4_ENST00000555597 RNASE4 P34096 Ribonuclease 4 chr14 GO:0016788 Not Cancer Driver No 24 0.163 9 2 0.222 0
RNASE8 RNASE8 Q8TDE3 Ribonuclease 8 chr14 GO:0016788 Not Cancer Driver No 18 0.117 17 2 0.118 0
RNASEH1 RNASEH1 O60930 Ribonuclease H1 chr2 GO:0016788 Not Cancer Driver No 33 0.115 124 20 0.161 2
RNASEH2A RNASEH2A O75792 Ribonuclease H2 subunit A chr19 GO:0016788 Not Cancer Driver No 42 0.14 31 3 0.097 7
RNASET2_ENST00000476238 RNASET2 O00584 Ribonuclease T2 chr6 GO:0016788 Not Cancer Driver No 32 0.125 37 3 0.081 1
RNGTT RNGTT O60942 mRNA-capping enzyme chr6 GO:0016788 Not Cancer Driver No 69 0.116 112 12 0.107 0
RPAP2 RPAP2 Q8IXW5 Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 chr1 GO:0016788 Not Cancer Driver No 56 0.092 293 25 0.085 0
RPE65 RPE65 Q16518 Retinoid isomerohydrolase chr1 GO:0016788 Not Cancer Driver No 109 0.205 10 1 0.1 44
RPP14_ENST00000295959 RPP14 O95059 Ribonuclease P protein subunit p14 chr3 GO:0016788 Not Cancer Driver No 8 0.065 0 0 0.0 0
RPP21_ENST00000442966 RPP21 Q9H633 Ribonuclease P protein subunit p21 chr6 GO:0016788 Not Cancer Driver No 16 0.104 51 4 0.078 0
RPP25 RPP25 Q9BUL9 Ribonuclease P protein subunit p25 chr15 GO:0016788 Not Cancer Driver No 11 0.055 162 11 0.068 0
RPP30_ENST00000371703 RPP30 P78346 Ribonuclease P protein subunit p30 chr10 GO:0016788 Not Cancer Driver No 28 0.104 21 2 0.095 0
RPP38_ENST00000378202 RPP38 P78345 Ribonuclease P protein subunit p38 chr10 GO:0016788 Not Cancer Driver No 36 0.127 118 19 0.161 0
RPP40 RPP40 O75818 Ribonuclease P protein subunit p40 chr6 GO:0016788 Not Cancer Driver No 51 0.14 5 0 0.0 0
SACM1L SACM1L Q9NTJ5 Phosphatidylinositol-3-phosphatase SAC1 chr3 GO:0016788 Not Cancer Driver No 41 0.07 0 0 0.0 0
SAMHD1 SAMHD1 Q9Y3Z3 Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 chr20 GO:0016788 Not Cancer Driver No 104 0.166 91 14 0.154 13
SBF1_ENST00000348911 SBF1 O95248 Myotubularin-related protein 5 chr22 GO:0016788 Not Cancer Driver No 210 0.112 632 63 0.1 2
SETMAR SETMAR Q53H47 Histone-lysine N-methyltransferase SETMAR chr3 GO:0016788 Not Cancer Driver No 62 0.091 154 12 0.078 0
SGPP1 SGPP1 Q9BX95 Sphingosine-1-phosphate phosphatase 1 chr14 GO:0016788 Not Cancer Driver No 48 0.109 116 1 0.009 0
SGPP2 SGPP2 Q8IWX5 Sphingosine-1-phosphate phosphatase 2 chr2 GO:0016788 Not Cancer Driver No 44 0.11 42 0 0.0 0
SGSH SGSH P51688 N-sulphoglucosamine sulphohydrolase chr17 GO:0016788 Not Cancer Driver No 45 0.09 44 2 0.045 56
SIAE SIAE Q9HAT2 Sialate O-acetylesterase chr11 GO:0016788 Not Cancer Driver No 53 0.101 10 3 0.3 9
SLX1B SLX1B Q9BQ83 Structure-specific endonuclease subunit SLX1 chr16 GO:0016788 Not Cancer Driver No 3 0.011 80 1 0.013 0
SMPD1 SMPD1 P17405 Sphingomyelin phosphodiesterase chr11 GO:0016788 Not Cancer Driver No 93 0.147 51 4 0.078 111
SMPD2 SMPD2 O60906 Sphingomyelin phosphodiesterase 2 chr6 GO:0016788 Not Cancer Driver No 45 0.106 48 5 0.104 0
SMPD3 SMPD3 Q9NY59 Sphingomyelin phosphodiesterase 3 chr16 GO:0016788 Not Cancer Driver No 92 0.14 224 29 0.129 0
SMPD4 SMPD4 Q9NXE4 Sphingomyelin phosphodiesterase 4 chr2 GO:0016788 Not Cancer Driver No 114 0.132 80 12 0.15 1
SMPDL3A SMPDL3A Q92484 Acid sphingomyelinase-like phosphodiesterase 3a chr6 GO:0016788 Not Cancer Driver No 56 0.124 36 3 0.083 0
SMPDL3B SMPDL3B Q92485 Acid sphingomyelinase-like phosphodiesterase 3b chr1 GO:0016788 Not Cancer Driver No 61 0.134 22 7 0.318 0
SSH1 SSH1 Q8WYL5 Protein phosphatase Slingshot homolog 1 chr12 GO:0016788 Not Cancer Driver No 129 0.123 658 85 0.129 0
SSH2_ENST00000269033 SSH2 Q76I76 Protein phosphatase Slingshot homolog 2 chr17 GO:0016788 Not Cancer Driver No 161 0.113 999 117 0.117 0
SSH3 SSH3 Q8TE77 Protein phosphatase Slingshot homolog 3 chr11 GO:0016788 Not Cancer Driver No 96 0.146 354 49 0.138 0
SSU72 SSU72 Q9NP77 RNA polymerase II subunit A C-terminal domain phosphatase SSU72 chr1 GO:0016788 Not Cancer Driver No 18 0.093 65 3 0.046 0
SSU72P2 SSU72P2 A0A1W2PQD8 RNA polymerase II subunit A C-terminal domain phosphatase SSU72 chr11 GO:0016788 Not Cancer Driver No 3 0.015 15 0 0.0 0
SSU72P3 SSU72P3 A0A1W2PQJ5 RNA polymerase II subunit A C-terminal domain phosphatase SSU72 chr11 GO:0016788 Not Cancer Driver No 2 0.01 17 0 0.0 0
SSU72P8 SSU72P8 A0A1W2PR75 RNA polymerase II subunit A C-terminal domain phosphatase SSU72 chr7 GO:0016788 Not Cancer Driver No 8 0.041 8 0 0.0 0
STS STS P08842 Steryl-sulfatase chrX GO:0016788 Not Cancer Driver No 113 0.194 48 7 0.146 7
STYX STYX Q8WUJ0 Serine/threonine/tyrosine-interacting protein chr14 GO:0016788 Not Cancer Driver No 20 0.09 30 2 0.067 0
STYXL1_ENST00000359697 STYXL1 Q9Y6J8 Serine/threonine/tyrosine-interacting-like protein 1 chr7 GO:0016788 Not Cancer Driver No 55 0.176 18 3 0.167 0
SULF1_ENST00000458141 SULF1 Q8IWU6 Extracellular sulfatase Sulf-1 chr8 GO:0016788 Not Cancer Driver No 246 0.282 269 71 0.264 0
SULF2_ENST00000484875 SULF2 Q8IWU5 Extracellular sulfatase Sulf-2 chr20 GO:0016788 Not Cancer Driver No 145 0.167 142 18 0.127 0
SYNJ1 SYNJ1 O43426 Synaptojanin-1 chr21 GO:0016788 Not Cancer Driver No 208 0.132 584 76 0.13 3
SYNJ2 SYNJ2 O15056 Synaptojanin-2 chr6 GO:0016788 Not Cancer Driver No 189 0.126 545 70 0.128 0
TARS2 TARS2 Q9BW92 Threonine--tRNA ligase, mitochondrial chr1 GO:0016788 Not Cancer Driver No 112 0.156 53 10 0.189 1
TDP1_ENST00000393454 TDP1 Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 chr14 GO:0016788 Not Cancer Driver No 81 0.133 179 25 0.14 1
TDP2 TDP2 O95551 Tyrosyl-DNA phosphodiesterase 2 chr6 GO:0016788 Not Cancer Driver No 55 0.152 80 10 0.125 0
TEFM TEFM Q96QE5 Transcription elongation factor, mitochondrial chr17 GO:0016788 Not Cancer Driver No 37 0.103 26 5 0.192 0
THEM4 THEM4 Q5T1C6 Acyl-coenzyme A thioesterase THEM4 chr1 GO:0016788 Not Cancer Driver No 19 0.079 14 0 0.0 0
THEM5 THEM5 Q8N1Q8 Acyl-coenzyme A thioesterase THEM5 chr1 GO:0016788 Not Cancer Driver No 39 0.158 1 0 0.0 0
TIGAR TIGAR Q9NQ88 Fructose-2,6-bisphosphatase TIGAR chr12 GO:0016788 Not Cancer Driver No 44 0.163 39 9 0.231 0
TOE1 TOE1 Q96GM8 Target of EGR1 protein 1 chr1 GO:0016788 Not Cancer Driver No 44 0.086 210 22 0.105 10
TPTE2 TPTE2 Q6XPS3 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2 chr13 GO:0016788 Not Cancer Driver No 210 0.402 33 13 0.394 0
TREX1_ENST00000625293 TREX1 Q9NSU2 Three-prime repair exonuclease 1 chr3 GO:0016788 Not Cancer Driver No 26 0.083 98 10 0.102 18
TREX2_ENST00000370231 TREX2 Q9BQ50 Three prime repair exonuclease 2 chrX GO:0016788 Not Cancer Driver No 33 0.14 23 6 0.261 0
TSEN2 TSEN2 Q8NCE0 tRNA-splicing endonuclease subunit Sen2 chr3 GO:0016788 Not Cancer Driver No 54 0.116 153 17 0.111 1
TSEN34_ENST00000396383 TSEN34 Q9BSV6 tRNA-splicing endonuclease subunit Sen34 chr19 GO:0016788 Not Cancer Driver No 40 0.129 176 22 0.125 1
USB1 USB1 Q9BQ65 U6 snRNA phosphodiesterase 1 chr16 GO:0016788 Not Cancer Driver No 28 0.106 76 5 0.066 0
VARS VARS1 P26640 Valine--tRNA ligase chr6 GO:0016788 Not Cancer Driver No 145 0.115 251 26 0.104 0
VARS2_ENST00000321897 VARS2 Q5ST30 Valine--tRNA ligase, mitochondrial chr6 GO:0016788 Not Cancer Driver No 111 0.104 253 21 0.083 3
XRCC1 XRCC1 P18887 DNA repair protein XRCC1 chr19 GO:0016788 Not Cancer Driver No 85 0.134 426 53 0.124 1
XRCC3_ENST00000352127 XRCC3 O43542 DNA repair protein XRCC3 chr14 GO:0016788 Not Cancer Driver No 24 0.069 35 2 0.057 1
XRN1 XRN1 Q8IZH2 5'-3' exoribonuclease 1 chr3 GO:0016788 Not Cancer Driver No 213 0.125 577 65 0.113 0
XRN2 XRN2 Q9H0D6 5'-3' exoribonuclease 2 chr20 GO:0016788 Not Cancer Driver No 129 0.136 427 63 0.148 0
ZC3H12A ZC3H12A Q5D1E8 Endoribonuclease ZC3H12A chr1 GO:0016788 Not Cancer Driver No 90 0.15 396 44 0.111 0
ZGRF1 ZGRF1 Q86YA3 Protein ZGRF1 chr4 GO:0016788 Not Cancer Driver No 216 0.103 881 95 0.108 0