Filter in search result
Please select a valid state.

Total number of protein in "GO:0016787" GO term:  1138

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
AADAC AADAC P22760 Arylacetamide deacetylase chr3 GO:0016787 Not Cancer Driver No 80 0.201 4 0 0.0 0
AADACL2 AADACL2 Q6P093 Arylacetamide deacetylase-like 2 chr3 GO:0016787 Not Cancer Driver No 102 0.254 5 3 0.6 0
AADACL3 AADACL3 Q5VUY0 Arylacetamide deacetylase-like 3 chr1 GO:0016787 Not Cancer Driver No 67 0.165 5 1 0.2 0
AADACL4 AADACL4 Q5VUY2 Arylacetamide deacetylase-like 4 chr1 GO:0016787 Not Cancer Driver No 91 0.224 0 0 0.0 0
AARS AARS1 P49588 Alanine--tRNA ligase, cytoplasmic chr16 GO:0016787 Not Cancer Driver No 97 0.1 140 14 0.1 5
AARS2 AARS2 Q5JTZ9 Alanine--tRNA ligase, mitochondrial chr6 GO:0016787 Not Cancer Driver No 123 0.125 203 25 0.123 5
AARSD1 AARSD1 Q9BTE6 Alanyl-tRNA editing protein Aarsd1 chr17 GO:0016787 Not Cancer Driver No 40 0.097 157 20 0.127 0
ABCC1 ABCC1 P33527 Multidrug resistance-associated protein 1 chr16 GO:0016787 Not Cancer Driver No 199 0.13 123 22 0.179 1
ABCD1 ABCD1 P33897 ATP-binding cassette sub-family D member 1 chrX GO:0016787 Not Cancer Driver No 106 0.142 75 5 0.067 138
ABCD2 ABCD2 Q9UBJ2 ATP-binding cassette sub-family D member 2 chr12 GO:0016787 Not Cancer Driver No 150 0.203 29 4 0.138 0
ABCD3 ABCD3 P28288 ATP-binding cassette sub-family D member 3 chr1 GO:0016787 Not Cancer Driver No 75 0.114 21 2 0.095 0
ABHD1 ABHD1 Q96SE0 Protein ABHD1 chr2 GO:0016787 Not Cancer Driver No 43 0.106 26 3 0.115 0
ABHD10 ABHD10 Q9NUJ1 Palmitoyl-protein thioesterase ABHD10, mitochondrial chr3 GO:0016787 Not Cancer Driver No 38 0.124 7 2 0.286 0
ABHD11 ABHD11 Q8NFV4 Protein ABHD11 chr7 GO:0016787 Not Cancer Driver No 38 0.121 73 6 0.082 0
ABHD12B ABHD12B Q7Z5M8 Protein ABHD12B chr14 GO:0016787 Not Cancer Driver No 34 0.094 16 1 0.062 0
ABHD12_ENST00000339157 ABHD12 Q8N2K0 Lysophosphatidylserine lipase ABHD12 chr20 GO:0016787 Not Cancer Driver No 45 0.113 8 1 0.125 1
ABHD13 ABHD13 Q7L211 Protein ABHD13 chr13 GO:0016787 Not Cancer Driver No 53 0.157 0 0 0.0 0
ABHD14B_ENST00000525795 ABHD14B Q96IU4 Putative protein-lysine deacylase ABHD14B chr3 GO:0016787 Not Cancer Driver No 12 0.057 17 2 0.118 0
ABHD15 ABHD15 Q6UXT9 Protein ABHD15 chr17 GO:0016787 Not Cancer Driver No 50 0.107 41 3 0.073 0
ABHD16A ABHD16A O95870 Phosphatidylserine lipase ABHD16A chr6 GO:0016787 Not Cancer Driver No 69 0.124 53 15 0.283 0
ABHD16B ABHD16B Q9H3Z7 Protein ABHD16B chr20 GO:0016787 Not Cancer Driver No 41 0.087 31 2 0.065 0
ABHD17A_ENST00000292577 ABHD17A Q96GS6 Alpha/beta hydrolase domain-containing protein 17A chr19 GO:0016787 Not Cancer Driver No 35 0.113 20 5 0.25 0
ABHD17B_ENST00000333421 ABHD17B Q5VST6 Alpha/beta hydrolase domain-containing protein 17B chr9 GO:0016787 Not Cancer Driver No 35 0.122 0 0 0.0 0
ABHD17C ABHD17C Q6PCB6 Alpha/beta hydrolase domain-containing protein 17C chr15 GO:0016787 Not Cancer Driver No 21 0.064 53 0 0.0 0
ABHD2_ENST00000565973 ABHD2 P08910 Monoacylglycerol lipase ABHD2 chr15 GO:0016787 Not Cancer Driver No 54 0.127 8 1 0.125 0
ABHD3 ABHD3 Q8WU67 Phospholipase ABHD3 chr18 GO:0016787 Not Cancer Driver No 43 0.105 0 0 0.0 0
ABHD4 ABHD4 Q8TB40 (Lyso)-N-acylphosphatidylethanolamine lipase chr14 GO:0016787 Not Cancer Driver No 46 0.135 39 5 0.128 0
AC010422.5 AC010422.5 M0R2P5 PAT complex subunit Asterix (Fragment) chr19 GO:0016787 Not Cancer Driver No 26 0.133 29 3 0.103 0
AC093525.1 AC093525.1 H3BQ15 Uncharacterized protein (Fragment) chr16 GO:0016787 Not Cancer Driver No 17 0.112 24 6 0.25 0
ACAA2 ACAA2 P42765 3-ketoacyl-CoA thiolase, mitochondrial chr18 GO:0016787 Not Cancer Driver No 42 0.106 51 2 0.039 0
ACE ACE P12821 Angiotensin-converting enzyme chr17 GO:0016787 Not Cancer Driver No 201 0.154 86 8 0.093 0
ACE2 ACE2 Q9BYF1 Angiotensin-converting enzyme 2 chrX GO:0016787 Not Cancer Driver No 104 0.129 68 5 0.074 0
ACER1 ACER1 Q8TDN7 Alkaline ceramidase 1 chr19 GO:0016787 Not Cancer Driver No 54 0.205 0 0 0.0 0
ACER2 ACER2 Q5QJU3 Alkaline ceramidase 2 chr9 GO:0016787 Not Cancer Driver No 27 0.098 0 0 0.0 0
ACER3 ACER3 Q9NUN7 Alkaline ceramidase 3 chr11 GO:0016787 Not Cancer Driver No 28 0.105 0 0 0.0 1
ACHE_ENST00000241069 ACHE P22303 Acetylcholinesterase chr7 GO:0016787 Not Cancer Driver No 81 0.132 64 8 0.125 0
ACMSD ACMSD Q8TDX5 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase chr2 GO:0016787 Not Cancer Driver No 65 0.193 9 2 0.222 0
ACOT1 ACOT1 Q86TX2 Acyl-coenzyme A thioesterase 1 chr14 GO:0016787 Not Cancer Driver No 28 0.067 22 0 0.0 0
ACOT11 ACOT11 Q8WXI4 Acyl-coenzyme A thioesterase 11 chr1 GO:0016787 Not Cancer Driver No 88 0.145 110 19 0.173 0
ACOT12 ACOT12 Q8WYK0 Acetyl-coenzyme A thioesterase chr5 GO:0016787 Not Cancer Driver No 93 0.168 41 3 0.073 0
ACOT13 ACOT13 Q9NPJ3 Acyl-coenzyme A thioesterase 13 chr6 GO:0016787 Not Cancer Driver No 15 0.107 23 2 0.087 0
ACOT2 ACOT2 P49753 Acyl-coenzyme A thioesterase 2, mitochondrial chr14 GO:0016787 Not Cancer Driver No 49 0.101 35 5 0.143 0
ACOT4 ACOT4 Q8N9L9 Peroxisomal succinyl-coenzyme A thioesterase chr14 GO:0016787 Not Cancer Driver No 53 0.126 13 1 0.077 0
ACOT6_ENST00000645972 ACOT6 Q3I5F7 Acyl-coenzyme A thioesterase 6 chr14 GO:0016787 Not Cancer Driver No 30 0.071 18 0 0.0 0
ACOT7 ACOT7 O00154 Cytosolic acyl coenzyme A thioester hydrolase chr1 GO:0016787 Not Cancer Driver No 43 0.113 77 16 0.208 0
ACOT8 ACOT8 O14734 Acyl-coenzyme A thioesterase 8 chr20 GO:0016787 Not Cancer Driver No 43 0.135 52 7 0.135 0
ACOT9_ENST00000336430 ACOT9 Q9Y305 Acyl-coenzyme A thioesterase 9, mitochondrial chrX GO:0016787 Not Cancer Driver No 45 0.103 45 3 0.067 0
ACP1_ENST00000272065 ACP1 P24666 Low molecular weight phosphotyrosine protein phosphatase chr2 GO:0016787 Not Cancer Driver No 28 0.177 13 2 0.154 0
ACP2 ACP2 P11117 Lysosomal acid phosphatase chr11 GO:0016787 Not Cancer Driver No 41 0.097 77 11 0.143 0
ACP4 ACP4 Q9BZG2 Testicular acid phosphatase chr19 GO:0016787 Not Cancer Driver No 66 0.155 28 7 0.25 3
ACP5_ENST00000433365 ACP5 P13686 Tartrate-resistant acid phosphatase type 5 chr19 GO:0016787 Not Cancer Driver No 51 0.157 31 6 0.194 8
ACP6 ACP6 Q9NPH0 Lysophosphatidic acid phosphatase type 6 chr1 GO:0016787 Not Cancer Driver No 53 0.124 40 5 0.125 0
ACP7 ACP7 Q6ZNF0 Acid phosphatase type 7 chr19 GO:0016787 Not Cancer Driver No 72 0.164 22 7 0.318 0
ACPP_ENST00000336375 ACP3 P15309 Prostatic acid phosphatase chr3 GO:0016787 Not Cancer Driver No 81 0.21 24 5 0.208 0
ACSBG2_ENST00000591403 ACSBG2 Q5FVE4 Long-chain-fatty-acid--CoA ligase ACSBG2 chr19 GO:0016787 Not Cancer Driver No 119 0.179 37 9 0.243 0
ACY1 ACY1 Q03154 Aminoacylase-1 chr3 GO:0016787 Not Cancer Driver No 49 0.12 48 6 0.125 7
ACY3 ACY3 Q96HD9 N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming) chr11 GO:0016787 Not Cancer Driver No 49 0.154 68 7 0.103 0
ACYP1_ENST00000238618 ACYP1 P07311 Acylphosphatase-1 chr14 GO:0016787 Not Cancer Driver No 13 0.131 31 4 0.129 0
ACYP2_ENST00000394666 ACYP2 P14621 Acylphosphatase-2 chr2 GO:0016787 Not Cancer Driver No 9 0.091 37 3 0.081 0
ADA ADA P00813 Adenosine deaminase chr20 GO:0016787 Not Cancer Driver No 50 0.138 44 9 0.205 27
ADA2 ADA2 Q9NZK5 Adenosine deaminase 2 chr22 GO:0016787 Not Cancer Driver No 97 0.19 1 0 0.0 10
ADAD1 ADAD1 Q96M93 Adenosine deaminase domain-containing protein 1 chr4 GO:0016787 Not Cancer Driver No 158 0.274 78 24 0.308 0
ADAD2_ENST00000315906 ADAD2 Q8NCV1 Adenosine deaminase domain-containing protein 2 chr16 GO:0016787 Not Cancer Driver No 87 0.149 191 39 0.204 0
ADAL ADAL Q6DHV7 Adenosine deaminase-like protein chr15 GO:0016787 Not Cancer Driver No 33 0.093 57 9 0.158 0
ADAM10 ADAM10 O14672 Disintegrin and metalloproteinase domain-containing protein 10 chr15 GO:0016787 Not Cancer Driver No 88 0.118 156 20 0.128 4
ADAM17 ADAM17 P78536 Disintegrin and metalloproteinase domain-containing protein 17 chr2 GO:0016787 Not Cancer Driver No 80 0.097 182 17 0.093 0
ADAM19_ENST00000517905 ADAM19 Q9H013 Disintegrin and metalloproteinase domain-containing protein 19 chr5 GO:0016787 Not Cancer Driver No 172 0.18 370 77 0.208 0
ADAR ADAR P55265 Double-stranded RNA-specific adenosine deaminase chr1 GO:0016787 Not Cancer Driver No 149 0.122 675 83 0.123 12
ADARB1 ADARB1 P78563 Double-stranded RNA-specific editase 1 chr21 GO:0016787 Not Cancer Driver No 102 0.138 348 34 0.098 1
ADARB2 ADARB2 Q9NS39 Double-stranded RNA-specific editase B2 chr10 GO:0016787 Not Cancer Driver No 154 0.208 331 69 0.208 0
ADAT1 ADAT1 Q9BUB4 tRNA-specific adenosine deaminase 1 chr16 GO:0016787 Not Cancer Driver No 60 0.12 162 15 0.093 0
ADAT2 ADAT2 Q7Z6V5 tRNA-specific adenosine deaminase 2 chr6 GO:0016787 Not Cancer Driver No 26 0.136 69 9 0.13 0
ADAT3 ADAT3 Q96EY9 Probable inactive tRNA-specific adenosine deaminase-like protein 3 chr19 GO:0016787 Not Cancer Driver No 16 0.046 153 2 0.013 1
ADGB ADGB Q8N7X0 Androglobin chr6 GO:0016787 Not Cancer Driver No 141 0.085 706 68 0.096 0
ADGRV1_ENST00000645211 ADGRV1 Q8WXG9 Adhesion G-protein coupled receptor V1 chr5 GO:0016787 Not Cancer Driver No 1124 0.178 496 77 0.155 2
ADPRH ADPRH P54922 ADP-ribosylhydrolase ARH1 chr3 GO:0016787 Not Cancer Driver No 54 0.151 30 3 0.1 0
ADPRHL1 ADPRHL1 Q8NDY3 Inactive ADP-ribosyltransferase ARH2 chr13 GO:0016787 Not Cancer Driver No 52 0.147 32 7 0.219 0
ADPRHL2 ADPRS Q9NX46 ADP-ribosylhydrolase ARH3 chr1 GO:0016787 Not Cancer Driver No 32 0.088 49 4 0.082 1
ADPRM ADPRM Q3LIE5 Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase chr17 GO:0016787 Not Cancer Driver No 38 0.111 32 4 0.125 0
ADTRP_ENST00000414691 ADTRP Q96IZ2 Androgen-dependent TFPI-regulating protein chr6 GO:0016787 Not Cancer Driver No 41 0.178 2 0 0.0 0
AEBP1 AEBP1 Q8IUX7 Adipocyte enhancer-binding protein 1 chr7 GO:0016787 Not Cancer Driver No 175 0.151 689 102 0.148 0
AFG3L2 AFG3L2 Q9Y4W6 AFG3-like protein 2 chr18 GO:0016787 Not Cancer Driver No 72 0.09 162 10 0.062 22
AFMID_ENST00000409257 AFMID Q63HM1 Kynurenine formamidase chr17 GO:0016787 Not Cancer Driver No 46 0.152 12 1 0.083 0
AGA AGA P20933 N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase chr4 GO:0016787 Not Cancer Driver No 46 0.133 78 11 0.141 12
AGBL1_ENST00000441037 AGBL1 Q96MI9 Cytosolic carboxypeptidase 4 chr15 GO:0016787 Not Cancer Driver No 258 0.232 165 45 0.273 1
AGBL2 AGBL2 Q5U5Z8 Cytosolic carboxypeptidase 2 chr11 GO:0016787 Not Cancer Driver No 117 0.13 246 29 0.118 0
AGBL4 AGBL4 Q5VU57 Cytosolic carboxypeptidase 6 chr1 GO:0016787 Not Cancer Driver No 65 0.129 72 2 0.028 0
AGBL5 AGBL5 Q8NDL9 Cytosolic carboxypeptidase-like protein 5 chr2 GO:0016787 Not Cancer Driver No 127 0.143 487 74 0.152 2
AGL_ENST00000361915 AGL P35573 Glycogen debranching enzyme chr1 GO:0016787 Not Cancer Driver No 182 0.119 143 23 0.161 1
AGMAT AGMAT Q9BSE5 Agmatinase, mitochondrial chr1 GO:0016787 Not Cancer Driver No 53 0.151 106 10 0.094 0
AGO2 AGO2 Q9UKV8 Protein argonaute-2 chr8 GO:0016787 Not Cancer Driver No 126 0.147 141 15 0.106 11
AGO3 AGO3 Q9H9G7 Protein argonaute-3 chr1 GO:0016787 Not Cancer Driver No 110 0.128 143 19 0.133 0
AGTPBP1_ENST00000357081 AGTPBP1 Q9UPW5 Cytosolic carboxypeptidase 1 chr9 GO:0016787 Not Cancer Driver No 158 0.129 321 42 0.131 4
AHCY AHCY P23526 Adenosylhomocysteinase chr20 GO:0016787 Not Cancer Driver No 58 0.134 0 0 0.0 4
AHCYL1 AHCYL1 O43865 S-adenosylhomocysteine hydrolase-like protein 1 chr1 GO:0016787 Not Cancer Driver No 58 0.109 108 10 0.093 0
AHCYL2 AHCYL2 Q96HN2 Adenosylhomocysteinase 3 chr7 GO:0016787 Not Cancer Driver No 76 0.124 208 23 0.111 0
AICDA AICDA Q9GZX7 Single-stranded DNA cytosine deaminase chr12 GO:0016787 Not Cancer Driver No 56 0.283 0 0 0.0 8
AIG1 AIG1 Q9NVV5 Androgen-induced gene 1 protein chr6 GO:0016787 Not Cancer Driver No 18 0.076 9 0 0.0 0
AKR7A2 AKR7A2 O43488 Aflatoxin B1 aldehyde reductase member 2 chr1 GO:0016787 Not Cancer Driver No 35 0.097 90 3 0.033 0
AL121900.2 AL121900.2 A0A087WZV9 D-aminoacyl-tRNA deacylase (Fragment) chr20 GO:0016787 Not Cancer Driver No 41 0.184 77 19 0.247 0
ALKBH2_ENST00000343075 ALKBH2 Q6NS38 DNA oxidative demethylase ALKBH2 chr12 GO:0016787 Not Cancer Driver No 34 0.13 73 14 0.192 0
ALOX12 ALOX12 P18054 Polyunsaturated fatty acid lipoxygenase ALOX12 chr17 GO:0016787 Not Cancer Driver No 73 0.11 73 12 0.164 0
ALOX5 ALOX5 P09917 Polyunsaturated fatty acid 5-lipoxygenase chr10 GO:0016787 Not Cancer Driver No 129 0.191 16 2 0.125 0
ALPG ALPG P10696 Alkaline phosphatase, germ cell type chr2 GO:0016787 Not Cancer Driver No 85 0.16 153 33 0.216 0
ALPI ALPI P09923 Intestinal-type alkaline phosphatase chr2 GO:0016787 Not Cancer Driver No 94 0.178 157 36 0.229 0
ALPL ALPL P05186 Alkaline phosphatase, tissue-nonspecific isozyme chr1 GO:0016787 Not Cancer Driver No 80 0.153 184 39 0.212 113
ALPP ALPP P05187 Alkaline phosphatase, placental type chr2 GO:0016787 Not Cancer Driver No 120 0.224 161 40 0.248 0
AMDHD1 AMDHD1 Q96NU7 Probable imidazolonepropionase chr12 GO:0016787 Not Cancer Driver No 72 0.169 23 5 0.217 0
AMDHD2_ENST00000293971 AMDHD2 Q9Y303 N-acetylglucosamine-6-phosphate deacetylase chr16 GO:0016787 Not Cancer Driver No 44 0.108 25 6 0.24 0
AMPD1 AMPD1 P23109 AMP deaminase 1 chr1 GO:0016787 Not Cancer Driver No 218 0.292 112 25 0.223 2
AMPD2_ENST00000528667 AMPD2 Q01433 AMP deaminase 2 chr1 GO:0016787 Not Cancer Driver No 93 0.106 275 27 0.098 3
AMPD3_ENST00000529507 AMPD3 Q01432 AMP deaminase 3 chr11 GO:0016787 Not Cancer Driver No 132 0.172 207 38 0.184 10
AMY1A AMY1A P0DUB6 Alpha-amylase 1A chr1 GO:0016787 Not Cancer Driver No 20 0.039 29 0 0.0 0
AMY1B_ENST00000370080 AMY1B P0DTE7 Alpha-amylase 1B chr1 GO:0016787 Not Cancer Driver No 14 0.027 29 0 0.0 0
AMY1C AMY1C P0DTE8 Alpha-amylase 1C chr1 GO:0016787 Not Cancer Driver No 37 0.072 29 2 0.069 0
AMY2A AMY2A P04746 Pancreatic alpha-amylase chr1 GO:0016787 Not Cancer Driver No 102 0.2 30 1 0.033 0
AMY2B AMY2B P19961 Alpha-amylase 2B chr1 GO:0016787 Not Cancer Driver No 140 0.274 32 11 0.344 0
ANPEP ANPEP P15144 Aminopeptidase N chr15 GO:0016787 Not Cancer Driver No 175 0.181 109 26 0.239 0
AOAH_ENST00000617537 AOAH P28039 Acyloxyacyl hydrolase chr7 GO:0016787 Not Cancer Driver No 111 0.193 68 10 0.147 0
APEX1_ENST00000555414 APEX1 P27695 DNA-(apurinic or apyrimidinic site) endonuclease chr14 GO:0016787 Not Cancer Driver No 34 0.107 103 14 0.136 0
APEX2 APEX2 Q9UBZ4 DNA-(apurinic or apyrimidinic site) endonuclease 2 chrX GO:0016787 Not Cancer Driver No 66 0.127 148 14 0.095 0
APMAP APMAP Q9HDC9 Adipocyte plasma membrane-associated protein chr20 GO:0016787 Not Cancer Driver No 66 0.159 72 11 0.153 0
APOBEC1 APOBEC1 P41238 C->U-editing enzyme APOBEC-1 chr12 GO:0016787 Not Cancer Driver No 62 0.263 13 1 0.077 0
APOBEC2 APOBEC2 Q9Y235 C->U-editing enzyme APOBEC-2 chr6 GO:0016787 Not Cancer Driver No 38 0.17 36 3 0.083 0
APOBEC3A_ENST00000249116 APOBEC3A P31941 DNA dC->dU-editing enzyme APOBEC-3A chr22 GO:0016787 Not Cancer Driver No 27 0.136 8 1 0.125 0
APOBEC3B APOBEC3B Q9UH17 DNA dC->dU-editing enzyme APOBEC-3B chr22 GO:0016787 Census Yes 61 0.16 1 0 0.0 0
APOBEC3C APOBEC3C Q9NRW3 DNA dC->dU-editing enzyme APOBEC-3C chr22 GO:0016787 Not Cancer Driver No 28 0.147 2 0 0.0 0
APOBEC3D APOBEC3D Q96AK3 DNA dC->dU-editing enzyme APOBEC-3D chr22 GO:0016787 Not Cancer Driver No 43 0.111 3 0 0.0 0
APOBEC3F APOBEC3F Q8IUX4 DNA dC->dU-editing enzyme APOBEC-3F chr22 GO:0016787 Not Cancer Driver No 49 0.131 0 0 0.0 0
APOBEC3G APOBEC3G Q9HC16 DNA dC->dU-editing enzyme APOBEC-3G chr22 GO:0016787 Not Cancer Driver No 61 0.159 0 0 0.0 0
APOBEC3H_ENST00000613677 APOBEC3H Q6NTF7 DNA dC->dU-editing enzyme APOBEC-3H chr22 GO:0016787 Not Cancer Driver No 39 0.195 0 0 0.0 0
APOBEC4 APOBEC4 Q8WW27 Putative C->U-editing enzyme APOBEC-4 chr1 GO:0016787 Not Cancer Driver No 43 0.117 98 12 0.122 0
APTX_ENST00000379819 APTX Q7Z2E3 Aprataxin chr9 GO:0016787 Not Cancer Driver No 36 0.101 101 6 0.059 9
ARG1_ENST00000368087 ARG1 P05089 Arginase-1 chr6 GO:0016787 Not Cancer Driver No 41 0.127 83 12 0.145 9
ARG2 ARG2 P78540 Arginase-2, mitochondrial chr14 GO:0016787 Not Cancer Driver No 25 0.071 58 3 0.052 0
ARL8B ARL8B Q9NVJ2 ADP-ribosylation factor-like protein 8B chr3 GO:0016787 Not Cancer Driver No 28 0.151 0 0 0.0 0
ARMT1 ARMT1 Q9H993 Damage-control phosphatase ARMT1 chr6 GO:0016787 Not Cancer Driver No 53 0.12 1 0 0.0 0
ARSA ARSA P15289 Arylsulfatase A chr22 GO:0016787 Not Cancer Driver No 46 0.091 61 7 0.115 97
ARSB ARSB P15848 Arylsulfatase B chr5 GO:0016787 Not Cancer Driver No 59 0.111 81 6 0.074 29
ARSD ARSD P51689 Arylsulfatase D chrX GO:0016787 Not Cancer Driver No 75 0.126 70 10 0.143 0
ARSE_ENST00000381134 ARSL P51690 Arylsulfatase L chrX GO:0016787 Not Cancer Driver No 85 0.144 4 1 0.25 9
ARSF_ENST00000359361 ARSF P54793 Arylsulfatase F chrX GO:0016787 Not Cancer Driver No 132 0.224 43 10 0.233 0
ARSG_ENST00000621439 ARSG Q96EG1 Arylsulfatase G chr17 GO:0016787 Not Cancer Driver No 86 0.164 66 10 0.152 1
ARSH ARSH Q5FYA8 Arylsulfatase H chrX GO:0016787 Not Cancer Driver No 84 0.149 13 4 0.308 0
ARSI ARSI Q5FYB1 Arylsulfatase I chr5 GO:0016787 Not Cancer Driver No 85 0.149 86 15 0.174 0
ARSJ ARSJ Q5FYB0 Arylsulfatase J chr4 GO:0016787 Not Cancer Driver No 70 0.117 142 17 0.12 0
ARSK ARSK Q6UWY0 Arylsulfatase K chr5 GO:0016787 Not Cancer Driver No 70 0.131 9 2 0.222 0
ASAH1_ENST00000262097 ASAH1 Q13510 Acid ceramidase chr8 GO:0016787 Not Cancer Driver No 47 0.119 10 3 0.3 14
ASAH2 ASAH2 Q9NR71 Neutral ceramidase chr10 GO:0016787 Not Cancer Driver No 71 0.091 140 24 0.171 0
ASAH2B_ENST00000374006 ASAH2B P0C7U1 Putative inactive neutral ceramidase B chr10 GO:0016787 Not Cancer Driver No 9 0.055 14 1 0.071 0
ASMTL ASMTL O95671 Probable bifunctional dTTP/UTP pyrophosphatase/methyltransferase protein chrX GO:0016787 Not Cancer Driver No 117 0.188 79 25 0.316 0
ASPA ASPA P45381 Aspartoacylase chr17 GO:0016787 Not Cancer Driver No 58 0.185 3 0 0.0 42
ASPG ASPG Q86U10 60 kDa lysophospholipase chr14 GO:0016787 Not Cancer Driver No 68 0.119 76 13 0.171 0
ASPRV1 ASPRV1 Q53RT3 Retroviral-like aspartic protease 1 chr2 GO:0016787 Not Cancer Driver No 66 0.192 85 18 0.212 3
ASRGL1_ENST00000301776 ASRGL1 Q7L266 Isoaspartyl peptidase/L-asparaginase chr11 GO:0016787 Not Cancer Driver No 43 0.14 74 12 0.162 0
ASTL ASTL Q6HA08 Astacin-like metalloendopeptidase chr2 GO:0016787 Not Cancer Driver No 101 0.234 179 44 0.246 0
ATIC ATIC P31939 Bifunctional purine biosynthesis protein ATIC chr2 GO:0016787 Census Yes 74 0.125 25 1 0.04 1
ATP5F1E_ENST00000395663 ATP5F1E P56381 ATP synthase subunit epsilon, mitochondrial chr20 GO:0016787 Not Cancer Driver No 3 0.059 1 0 0.0 1
ATP6V0E1 ATP6V0E1 O15342 V-type proton ATPase subunit e 1 chr5 GO:0016787 Not Cancer Driver No 11 0.136 0 0 0.0 0
ATP6V0E2_ENST00000425642 ATP6V0E2 Q8NHE4 V-type proton ATPase subunit e 2 chr7 GO:0016787 Not Cancer Driver No 11 0.136 0 0 0.0 0
ATP6V1B1 ATP6V1B1 P15313 V-type proton ATPase subunit B, kidney isoform chr2 GO:0016787 Not Cancer Driver No 77 0.15 66 14 0.212 9
ATP6V1B2 ATP6V1B2 P21281 V-type proton ATPase subunit B, brain isoform chr8 GO:0016787 Not Cancer Driver No 63 0.123 49 4 0.082 1
ATP6V1E1 ATP6V1E1 P36543 V-type proton ATPase subunit E 1 chr22 GO:0016787 Not Cancer Driver No 27 0.119 27 3 0.111 2
ATXN3 ATXN3 P54252 Ataxin-3 chr14 GO:0016787 Not Cancer Driver No 46 0.127 181 24 0.133 0
BAAT_ENST00000395051 BAAT Q14032 Bile acid-CoA:amino acid N-acyltransferase chr9 GO:0016787 Not Cancer Driver No 88 0.211 10 4 0.4 1
BACE1 BACE1 P56817 Beta-secretase 1 chr11 GO:0016787 Not Cancer Driver No 55 0.11 53 5 0.094 0
BACE2 BACE2 Q9Y5Z0 Beta-secretase 2 chr21 GO:0016787 Not Cancer Driver No 61 0.118 23 2 0.087 0
BANK1 BANK1 Q8NDB2 B-cell scaffold protein with ankyrin repeats chr4 GO:0016787 Not Cancer Driver No 150 0.191 394 73 0.185 0
BCHE BCHE P06276 Cholinesterase chr3 GO:0016787 Not Cancer Driver No 185 0.307 14 4 0.286 38
BDKRB2 BDKRB2 P30411 B2 bradykinin receptor chr14 GO:0016787 Not Cancer Driver No 81 0.207 0 0 0.0 0
BLMH BLMH Q13867 Bleomycin hydrolase chr17 GO:0016787 Not Cancer Driver No 54 0.119 15 1 0.067 0
BPGM_ENST00000344924 BPGM P07738 Bisphosphoglycerate mutase chr7 GO:0016787 Not Cancer Driver No 34 0.131 15 0 0.0 2
BPHL BPHL Q86WA6 Valacyclovir hydrolase chr6 GO:0016787 Not Cancer Driver No 35 0.12 12 1 0.083 0
BPNT1_ENST00000322067 BPNT1 O95861 3'(2'),5'-bisphosphate nucleotidase 1 chr1 GO:0016787 Not Cancer Driver No 44 0.143 9 0 0.0 0
BRCC3 BRCC3 P46736 Lys-63-specific deubiquitinase BRCC36 chrX GO:0016787 Not Cancer Driver No 39 0.123 74 7 0.095 0
BST1 BST1 Q10588 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 chr4 GO:0016787 Not Cancer Driver No 40 0.126 11 0 0.0 0
BTD_ENST00000643237 BTD P43251 Biotinidase chr3 GO:0016787 Not Cancer Driver No 63 0.116 13 1 0.077 9
C9orf3 AOPEP Q8N6M6 Aminopeptidase O chr9 GO:0016787 Not Cancer Driver No 87 0.106 107 13 0.121 0
CA1_ENST00000431316 CA1 P00915 Carbonic anhydrase 1 chr8 GO:0016787 Not Cancer Driver No 50 0.192 100 18 0.18 0
CA2 CA2 P00918 Carbonic anhydrase 2 chr8 GO:0016787 Not Cancer Driver No 41 0.158 55 8 0.145 4
CAD CAD P27708 CAD protein chr2 GO:0016787 Not Cancer Driver No 287 0.129 368 52 0.141 1
CAMK2G_ENST00000423381 CAMK2G Q13555 Calcium/calmodulin-dependent protein kinase type II subunit gamma chr10 GO:0016787 Not Cancer Driver No 68 0.122 145 14 0.097 1
CANT1 CANT1 Q8WVQ1 Soluble calcium-activated nucleotidase 1 chr17 GO:0016787 Census Yes 57 0.142 48 5 0.104 12
CAPN10 CAPN10 Q9HC96 Calpain-10 chr2 GO:0016787 Not Cancer Driver No 87 0.129 52 6 0.115 0
CAPN11 CAPN11 Q9UMQ6 Calpain-11 chr6 GO:0016787 Not Cancer Driver No 96 0.13 103 12 0.117 0
CAPN12 CAPN12 Q6ZSI9 Calpain-12 chr19 GO:0016787 Not Cancer Driver No 83 0.115 62 9 0.145 0
CAPN13 CAPN13 Q6MZZ7 Calpain-13 chr2 GO:0016787 Not Cancer Driver No 155 0.232 73 24 0.329 0
CAPN14 CAPN14 A8MX76 Calpain-14 chr2 GO:0016787 Not Cancer Driver No 47 0.069 22 2 0.091 0
CAPN15 CAPN15 O75808 Calpain-15 chr16 GO:0016787 Not Cancer Driver No 98 0.09 385 29 0.075 0
CAPN1_ENST00000533129 CAPN1 P07384 Calpain-1 catalytic subunit chr11 GO:0016787 Not Cancer Driver No 68 0.095 32 2 0.062 1
CAPN2 CAPN2 P17655 Calpain-2 catalytic subunit chr1 GO:0016787 Not Cancer Driver No 81 0.116 46 11 0.239 0
CAPN3 CAPN3 P20807 Calpain-3 chr15 GO:0016787 Not Cancer Driver No 111 0.135 168 11 0.065 52
CAPN5 CAPN5 O15484 Calpain-5 chr11 GO:0016787 Not Cancer Driver No 103 0.161 110 25 0.227 2
CAPN6 CAPN6 Q9Y6Q1 Calpain-6 chrX GO:0016787 Not Cancer Driver No 156 0.243 19 8 0.421 0
CAPN7 CAPN7 Q9Y6W3 Calpain-7 chr3 GO:0016787 Not Cancer Driver No 80 0.098 92 9 0.098 0
CAPN8 CAPN8 A6NHC0 Calpain-8 chr1 GO:0016787 Not Cancer Driver No 36 0.051 76 6 0.079 0
CAPN9 CAPN9 O14815 Calpain-9 chr1 GO:0016787 Not Cancer Driver No 110 0.159 81 17 0.21 0
CAPNS1 CAPNS1 P04632 Calpain small subunit 1 chr19 GO:0016787 Not Cancer Driver No 30 0.112 58 5 0.086 0
CAPNS2 CAPNS2 Q96L46 Calpain small subunit 2 chr16 GO:0016787 Not Cancer Driver No 21 0.085 56 5 0.089 0
CASP1 CASP1 P29466 Caspase-1 chr11 GO:0016787 Not Cancer Driver No 79 0.196 87 18 0.207 0
CASP10_ENST00000272879 CASP10 Q92851 Caspase-10 chr2 GO:0016787 Not Cancer Driver No 57 0.109 126 17 0.135 3
CASP12 CASP12 Q6UXS9 Inactive caspase-12 chr11 GO:0016787 Not Cancer Driver No 12 0.035 31 1 0.032 0
CASP14 CASP14 P31944 Caspase-14 chr19 GO:0016787 Not Cancer Driver No 50 0.207 84 13 0.155 0
CASP2 CASP2 P42575 Caspase-2 chr7 GO:0016787 Not Cancer Driver No 63 0.139 42 12 0.286 0
CASP3 CASP3 P42574 Caspase-3 chr4 GO:0016787 Census Yes 32 0.116 62 5 0.081 0
CASP4 CASP4 P49662 Caspase-4 chr11 GO:0016787 Not Cancer Driver No 56 0.149 102 14 0.137 0
CASP5_ENST00000260315 CASP5 P51878 Caspase-5 chr11 GO:0016787 Not Cancer Driver No 103 0.237 61 17 0.279 0
CASP6 CASP6 P55212 Caspase-6 chr4 GO:0016787 Not Cancer Driver No 28 0.096 24 4 0.167 0
CASP7_ENST00000345633 CASP7 P55210 Caspase-7 chr10 GO:0016787 Not Cancer Driver No 38 0.125 73 10 0.137 0
CASP8_ENST00000432109 CASP8 Q14790 Caspase-8 chr2 GO:0016787 Census, Compendium Yes 142 0.296 106 12 0.113 1
CASP9 CASP9 P55211 Caspase-9 chr1 GO:0016787 Census Yes 49 0.118 71 7 0.099 0
CASR_ENST00000638421 CASR P41180 Extracellular calcium-sensing receptor chr3 GO:0016787 Not Cancer Driver No 304 0.282 189 60 0.317 108
CAT CAT P04040 Catalase chr11 GO:0016787 Not Cancer Driver No 70 0.133 176 18 0.102 0
CCR1 CCR1 P32246 C-C chemokine receptor type 1 chr3 GO:0016787 Not Cancer Driver No 69 0.194 14 5 0.357 0
CCR5 CCR5 P51681 C-C chemokine receptor type 5 chr3 GO:0016787 Not Cancer Driver No 107 0.304 0 0 0.0 0
CD38 CD38 P28907 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 chr4 GO:0016787 Not Cancer Driver No 54 0.18 3 1 0.333 0
CDA CDA P32320 Cytidine deaminase chr1 GO:0016787 Not Cancer Driver No 21 0.144 8 0 0.0 0
CDADC1 CDADC1 Q9BWV3 Cytidine and dCMP deaminase domain-containing protein 1 chr13 GO:0016787 Not Cancer Driver No 52 0.101 122 13 0.107 0
CDC14A_ENST00000336454 CDC14A Q9UNH5 Dual specificity protein phosphatase CDC14A chr1 GO:0016787 Not Cancer Driver No 91 0.153 246 43 0.175 3
CDC14B CDC14B O60729 Dual specificity protein phosphatase CDC14B chr9 GO:0016787 Not Cancer Driver No 61 0.122 138 15 0.109 0
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 GO:0016787 Not Cancer Driver No 39 0.204 23 2 0.087 1
CDKN3 CDKN3 Q16667 Cyclin-dependent kinase inhibitor 3 chr14 GO:0016787 Not Cancer Driver No 13 0.061 33 1 0.03 9
CEL CEL P19835 Bile salt-activated lipase chr9 GO:0016787 Not Cancer Driver No 101 0.134 280 40 0.143 0
CEMIP2 CEMIP2 Q9UHN6 Cell surface hyaluronidase chr9 GO:0016787 Not Cancer Driver No 198 0.143 229 26 0.114 0
CEMIP_ENST00000356249 CEMIP Q8WUJ3 Cell migration-inducing and hyaluronan-binding protein chr15 GO:0016787 Not Cancer Driver No 207 0.152 105 10 0.095 0
CES1_ENST00000361503 CES1 P23141 Liver carboxylesterase 1 chr16 GO:0016787 Not Cancer Driver No 138 0.243 41 2 0.049 0
CES3 CES3 Q6UWW8 Carboxylesterase 3 chr16 GO:0016787 Not Cancer Driver No 94 0.165 112 13 0.116 0
CES5A_ENST00000290567 CES5A Q6NT32 Carboxylesterase 5A chr16 GO:0016787 Not Cancer Driver No 115 0.2 18 2 0.111 0
CFLAR CFLAR O15519 CASP8 and FADD-like apoptosis regulator chr2 GO:0016787 Not Cancer Driver No 40 0.083 44 2 0.045 0
CHIT1 CHIT1 Q13231 Chitotriosidase-1 chr1 GO:0016787 Not Cancer Driver No 86 0.185 85 11 0.129 0
CHKA CHKA P35790 Choline kinase alpha chr11 GO:0016787 Not Cancer Driver No 45 0.098 119 4 0.034 0
CHRM1 CHRM1 P11229 Muscarinic acetylcholine receptor M1 chr11 GO:0016787 Not Cancer Driver No 63 0.137 131 24 0.183 0
CHRM3_ENST00000615928 CHRM3 P20309 Muscarinic acetylcholine receptor M3 chr1 GO:0016787 Not Cancer Driver No 182 0.308 136 42 0.309 0
CHRM5 CHRM5 P08912 Muscarinic acetylcholine receptor M5 chr15 GO:0016787 Not Cancer Driver No 74 0.139 155 20 0.129 0
CILP CILP O75339 Cartilage intermediate layer protein 1 chr15 GO:0016787 Not Cancer Driver No 206 0.174 278 44 0.158 0
CILP2 CILP2 Q8IUL8 Cartilage intermediate layer protein 2 chr19 GO:0016787 Not Cancer Driver No 207 0.179 401 86 0.214 0
CLPP CLPP Q16740 ATP-dependent Clp protease proteolytic subunit, mitochondrial chr19 GO:0016787 Not Cancer Driver No 22 0.079 83 9 0.108 3
CLPX CLPX O76031 ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial chr15 GO:0016787 Not Cancer Driver No 66 0.104 195 22 0.113 1
CLYBL CLYBL Q8N0X4 Citramalyl-CoA lyase, mitochondrial chr13 GO:0016787 Not Cancer Driver No 48 0.141 0 0 0.0 0
CMBL CMBL Q96DG6 Carboxymethylenebutenolidase homolog chr5 GO:0016787 Not Cancer Driver No 29 0.118 0 0 0.0 0
CNDP1 CNDP1 Q96KN2 Beta-Ala-His dipeptidase chr18 GO:0016787 Not Cancer Driver No 104 0.205 26 3 0.115 0
CNDP2_ENST00000579847 CNDP2 Q96KP4 Cytosolic non-specific dipeptidase chr18 GO:0016787 Not Cancer Driver No 67 0.141 39 5 0.128 0
CNOT1 CNOT1 A5YKK6 CCR4-NOT transcription complex subunit 1 chr16 GO:0016787 Not Cancer Driver No 346 0.146 464 56 0.121 12
CNOT2 CNOT2 Q9NZN8 CCR4-NOT transcription complex subunit 2 chr12 GO:0016787 Not Cancer Driver No 84 0.156 354 66 0.186 0
CNOT6L CNOT6L Q96LI5 CCR4-NOT transcription complex subunit 6-like chr4 GO:0016787 Not Cancer Driver No 58 0.105 37 3 0.081 0
CNOT6_ENST00000261951 CNOT6 Q9ULM6 CCR4-NOT transcription complex subunit 6 chr5 GO:0016787 Not Cancer Driver No 65 0.117 66 4 0.061 0
CNOT7 CNOT7 Q9UIV1 CCR4-NOT transcription complex subunit 7 chr8 GO:0016787 Not Cancer Driver No 31 0.109 21 1 0.048 0
CNOT8 CNOT8 Q9UFF9 CCR4-NOT transcription complex subunit 8 chr5 GO:0016787 Not Cancer Driver No 30 0.103 6 0 0.0 0
CNP CNP P09543 2',3'-cyclic-nucleotide 3'-phosphodiesterase chr17 GO:0016787 Not Cancer Driver No 36 0.086 71 2 0.028 0
COPS4_ENST00000264389 COPS4 Q9BT78 COP9 signalosome complex subunit 4 chr4 GO:0016787 Not Cancer Driver No 50 0.123 13 0 0.0 0
COPS5 COPS5 Q92905 COP9 signalosome complex subunit 5 chr8 GO:0016787 Not Cancer Driver No 36 0.108 32 7 0.219 0
COPS6 COPS6 Q7L5N1 COP9 signalosome complex subunit 6 chr7 GO:0016787 Not Cancer Driver No 38 0.116 30 6 0.2 0
CPA1 CPA1 P15085 Carboxypeptidase A1 chr7 GO:0016787 Not Cancer Driver No 84 0.2 5 1 0.2 0
CPA2 CPA2 P48052 Carboxypeptidase A2 chr7 GO:0016787 Not Cancer Driver No 62 0.148 26 2 0.077 0
CPA3 CPA3 P15088 Mast cell carboxypeptidase A chr3 GO:0016787 Not Cancer Driver No 111 0.266 38 9 0.237 0
CPA4 CPA4 Q9UI42 Carboxypeptidase A4 chr7 GO:0016787 Not Cancer Driver No 76 0.181 59 12 0.203 0
CPA5_ENST00000461828 CPA5 Q8WXQ8 Carboxypeptidase A5 chr7 GO:0016787 Not Cancer Driver No 79 0.181 40 4 0.1 0
CPA6 CPA6 Q8N4T0 Carboxypeptidase A6 chr8 GO:0016787 Not Cancer Driver No 106 0.243 7 0 0.0 2
CPB1_ENST00000282957 CPB1 P15086 Carboxypeptidase B chr3 GO:0016787 Not Cancer Driver No 91 0.218 15 2 0.133 0
CPB2_ENST00000645658 CPB2 Q96IY4 Carboxypeptidase B2 chr13 GO:0016787 Not Cancer Driver No 59 0.139 2 0 0.0 0
CPD CPD O75976 Carboxypeptidase D chr17 GO:0016787 Not Cancer Driver No 131 0.095 476 45 0.095 0
CPE CPE P16870 Carboxypeptidase E chr4 GO:0016787 Not Cancer Driver No 98 0.206 127 24 0.189 0
CPM CPM P14384 Carboxypeptidase M chr12 GO:0016787 Not Cancer Driver No 65 0.147 16 2 0.125 0
CPN1 CPN1 P15169 Carboxypeptidase N catalytic chain chr10 GO:0016787 Not Cancer Driver No 98 0.214 124 27 0.218 1
CPO CPO Q8IVL8 Carboxypeptidase O chr2 GO:0016787 Not Cancer Driver No 62 0.166 16 2 0.125 0
CPQ CPQ Q9Y646 Carboxypeptidase Q chr8 GO:0016787 Not Cancer Driver No 110 0.233 3 0 0.0 0
CPSF3 CPSF3 Q9UKF6 Cleavage and polyadenylation specificity factor subunit 3 chr2 GO:0016787 Not Cancer Driver No 78 0.114 56 9 0.161 0
CPVL_ENST00000265394 CPVL Q9H3G5 Probable serine carboxypeptidase CPVL chr7 GO:0016787 Not Cancer Driver No 81 0.17 0 0 0.0 0
CPXM1 CPXM1 Q96SM3 Probable carboxypeptidase X1 chr20 GO:0016787 Not Cancer Driver No 128 0.174 252 35 0.139 0
CPXM2 CPXM2 Q8N436 Inactive carboxypeptidase-like protein X2 chr10 GO:0016787 Not Cancer Driver No 198 0.262 259 64 0.247 0
CPZ CPZ Q66K79 Carboxypeptidase Z chr4 GO:0016787 Not Cancer Driver No 163 0.25 71 31 0.437 0
CTDP1 CTDP1 Q9Y5B0 RNA polymerase II subunit A C-terminal domain phosphatase chr18 GO:0016787 Not Cancer Driver No 121 0.126 624 87 0.139 0
CTDSP1 CTDSP1 Q9GZU7 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 chr2 GO:0016787 Not Cancer Driver No 34 0.13 46 2 0.043 0
CTDSP2 CTDSP2 O14595 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 chr12 GO:0016787 Not Cancer Driver No 35 0.129 18 0 0.0 0
CTDSPL CTDSPL O15194 CTD small phosphatase-like protein chr3 GO:0016787 Not Cancer Driver No 32 0.116 60 4 0.067 0
CTDSPL2 CTDSPL2 Q05D32 CTD small phosphatase-like protein 2 chr15 GO:0016787 Not Cancer Driver No 47 0.101 256 27 0.105 0
CTSA_ENST00000372459 CTSA P10619 Lysosomal protective protein chr20 GO:0016787 Not Cancer Driver No 59 0.123 14 1 0.071 12
CTSC CTSC P53634 Dipeptidyl peptidase 1 chr11 GO:0016787 Not Cancer Driver No 64 0.138 19 5 0.263 29
CTSD CTSD P07339 Cathepsin D chr11 GO:0016787 Not Cancer Driver No 57 0.138 6 1 0.167 2
CTSE CTSE P14091 Cathepsin E chr1 GO:0016787 Not Cancer Driver No 59 0.149 23 2 0.087 0
CTSH CTSH P09668 Pro-cathepsin H chr15 GO:0016787 Not Cancer Driver No 45 0.134 4 0 0.0 0
CYLD CYLD Q9NQC7 Ubiquitin carboxyl-terminal hydrolase CYLD chr16 GO:0016787 Census, Compendium Yes 116 0.121 213 31 0.146 3
DARS DARS1 P14868 Aspartate--tRNA ligase, cytoplasmic chr2 GO:0016787 Not Cancer Driver No 55 0.11 110 21 0.191 8
DBR1 DBR1 Q9UK59 Lariat debranching enzyme chr3 GO:0016787 Not Cancer Driver No 58 0.107 185 28 0.151 3
DCLRE1A DCLRE1A Q6PJP8 DNA cross-link repair 1A protein chr10 GO:0016787 Not Cancer Driver No 92 0.088 514 45 0.088 0
DCLRE1B DCLRE1B Q9H816 5' exonuclease Apollo chr1 GO:0016787 Not Cancer Driver No 65 0.122 127 17 0.134 0
DCLRE1C DCLRE1C Q96SD1 Protein artemis chr10 GO:0016787 Not Cancer Driver No 76 0.11 277 26 0.094 3
DCP1A DCP1A Q9NPI6 mRNA-decapping enzyme 1A chr3 GO:0016787 Not Cancer Driver No 46 0.079 382 31 0.081 0
DCP1B DCP1B Q8IZD4 mRNA-decapping enzyme 1B chr12 GO:0016787 Not Cancer Driver No 82 0.133 406 63 0.155 0
DCP2 DCP2 Q8IU60 m7GpppN-mRNA hydrolase chr5 GO:0016787 Not Cancer Driver No 57 0.136 167 24 0.144 0
DCPS DCPS Q96C86 m7GpppX diphosphatase chr11 GO:0016787 Not Cancer Driver No 48 0.142 53 6 0.113 1
DCTD_ENST00000438320 DCTD P32321 Deoxycytidylate deaminase chr4 GO:0016787 Not Cancer Driver No 33 0.185 3 0 0.0 0
DCTPP1 DCTPP1 Q9H773 dCTP pyrophosphatase 1 chr16 GO:0016787 Not Cancer Driver No 14 0.082 88 9 0.102 0
DDAH1 DDAH1 O94760 N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 chr1 GO:0016787 Not Cancer Driver No 28 0.098 44 3 0.068 0
DDAH2_ENST00000375787 DDAH2 O95865 N(G),N(G)-dimethylarginine dimethylaminohydrolase 2 chr6 GO:0016787 Not Cancer Driver No 24 0.084 96 6 0.062 0
DDI1 DDI1 Q8WTU0 Protein DDI1 homolog 1 chr11 GO:0016787 Not Cancer Driver No 151 0.381 166 73 0.44 0
DDI2 DDI2 Q5TDH0 Protein DDI1 homolog 2 chr1 GO:0016787 Not Cancer Driver No 47 0.118 187 30 0.16 0
DDX3X_ENST00000629496 DDX3X O00571 ATP-dependent RNA helicase DDX3X chrX GO:0016787 Census, Compendium Yes 133 0.201 301 47 0.156 18
DESI1 DESI1 Q6ICB0 Desumoylating isopeptidase 1 chr22 GO:0016787 Not Cancer Driver No 23 0.137 34 6 0.176 0
DESI2 DESI2 Q9BSY9 Deubiquitinase DESI2 chr1 GO:0016787 Not Cancer Driver No 24 0.124 36 8 0.222 0
DHODH DHODH Q02127 Dihydroorotate dehydrogenase (quinone), mitochondrial chr16 GO:0016787 Not Cancer Driver No 44 0.111 96 11 0.115 10
DICER1 DICER1 Q9UPY3 Endoribonuclease Dicer chr14 GO:0016787 Census, Compendium Yes 264 0.137 362 45 0.124 4
DNA2 DNA2 P51530 DNA replication ATP-dependent helicase/nuclease DNA2 chr10 GO:0016787 Not Cancer Driver No 120 0.113 52 8 0.154 3
DNASE1L1 DNASE1L1 P49184 Deoxyribonuclease-1-like 1 chrX GO:0016787 Not Cancer Driver No 30 0.099 0 0 0.0 0
DNASE1L2_ENST00000567494 DNASE1L2 Q92874 Deoxyribonuclease-1-like 2 chr16 GO:0016787 Not Cancer Driver No 23 0.077 15 1 0.067 0
DNASE1L3 DNASE1L3 Q13609 Deoxyribonuclease gamma chr3 GO:0016787 Not Cancer Driver No 43 0.141 15 4 0.267 0
DNASE1_ENST00000246949 DNASE1 P24855 Deoxyribonuclease-1 chr16 GO:0016787 Not Cancer Driver No 24 0.085 0 0 0.0 0
DNASE2 DNASE2 O00115 Deoxyribonuclease-2-alpha chr19 GO:0016787 Not Cancer Driver No 46 0.128 48 7 0.146 0
DNASE2B DNASE2B Q8WZ79 Deoxyribonuclease-2-beta chr1 GO:0016787 Not Cancer Driver No 53 0.147 14 1 0.071 0
DNPEP_ENST00000273075 DNPEP Q9ULA0 Aspartyl aminopeptidase chr2 GO:0016787 Not Cancer Driver No 55 0.113 90 8 0.089 0
DNPH1 DNPH1 O43598 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 chr6 GO:0016787 Not Cancer Driver No 15 0.086 49 3 0.061 0
DOLPP1 DOLPP1 Q86YN1 Dolichyldiphosphatase 1 chr9 GO:0016787 Not Cancer Driver No 21 0.088 2 0 0.0 0
DPEP1 DPEP1 P16444 Dipeptidase 1 chr16 GO:0016787 Not Cancer Driver No 54 0.131 41 6 0.146 0
DPEP2_ENST00000393847 DPEP2 Q9H4A9 Dipeptidase 2 chr16 GO:0016787 Not Cancer Driver No 66 0.136 73 4 0.055 0
DPEP3 DPEP3 Q9H4B8 Dipeptidase 3 chr16 GO:0016787 Not Cancer Driver No 72 0.148 105 14 0.133 0
DPH7 DPH7 Q9BTV6 Diphthine methyltransferase chr9 GO:0016787 Not Cancer Driver No 38 0.084 107 10 0.093 0
DPP10_ENST00000410059 DPP10 Q8N608 Inactive dipeptidyl peptidase 10 chr2 GO:0016787 Not Cancer Driver No 319 0.401 38 17 0.447 0
DPP3 DPP3 Q9NY33 Dipeptidyl peptidase 3 chr11 GO:0016787 Not Cancer Driver No 96 0.13 64 11 0.172 0
DPP4 DPP4 P27487 Dipeptidyl peptidase 4 chr2 GO:0016787 Not Cancer Driver No 151 0.197 8 1 0.125 0
DPP6 DPP6 P42658 Dipeptidyl aminopeptidase-like protein 6 chr7 GO:0016787 Not Cancer Driver No 244 0.282 181 45 0.249 1
DPP7 DPP7 Q9UHL4 Dipeptidyl peptidase 2 chr9 GO:0016787 Not Cancer Driver No 41 0.083 29 0 0.0 0
DPP8_ENST00000559233 DPP8 Q6V1X1 Dipeptidyl peptidase 8 chr15 GO:0016787 Not Cancer Driver No 99 0.11 71 5 0.07 0
DPP9_ENST00000598800 DPP9 Q86TI2 Dipeptidyl peptidase 9 chr19 GO:0016787 Not Cancer Driver No 94 0.109 83 15 0.181 0
DROSHA_ENST00000344624 DROSHA Q9NRR4 Ribonuclease 3 chr5 GO:0016787 Census, Compendium Yes 175 0.127 682 100 0.147 0
DTD1 DTD1 Q8TEA8 D-aminoacyl-tRNA deacylase 1 chr20 GO:0016787 Not Cancer Driver No 45 0.215 93 26 0.28 0
DTD2_ENST00000356180 DTD2 Q96FN9 D-aminoacyl-tRNA deacylase 2 chr14 GO:0016787 Not Cancer Driver No 12 0.071 11 1 0.091 0
DUPD1 DUSP29 Q68J44 Dual specificity phosphatase 29 chr10 GO:0016787 Not Cancer Driver No 47 0.214 55 7 0.127 0
DUSP1 DUSP1 P28562 Dual specificity protein phosphatase 1 chr5 GO:0016787 Not Cancer Driver No 31 0.084 7 0 0.0 0
DUSP10 DUSP10 Q9Y6W6 Dual specificity protein phosphatase 10 chr1 GO:0016787 Not Cancer Driver No 81 0.168 135 24 0.178 0
DUSP11 DUSP11 O75319 RNA/RNP complex-1-interacting phosphatase chr2 GO:0016787 Not Cancer Driver No 42 0.111 157 12 0.076 0
DUSP12 DUSP12 Q9UNI6 Dual specificity protein phosphatase 12 chr1 GO:0016787 Not Cancer Driver No 33 0.097 30 1 0.033 0
DUSP13_ENST00000472493 DUSP13 Q9UII6 Dual specificity protein phosphatase 13 isoform B chr10 GO:0016787 Not Cancer Driver No 45 0.227 16 1 0.062 0
DUSP15 DUSP15 Q9H1R2 Dual specificity protein phosphatase 15 chr20 GO:0016787 Not Cancer Driver No 36 0.122 122 19 0.156 0
DUSP16 DUSP16 Q9BY84 Dual specificity protein phosphatase 16 chr12 GO:0016787 Compendium Yes 70 0.105 273 34 0.125 0
DUSP18_ENST00000404885 DUSP18 Q8NEJ0 Dual specificity protein phosphatase 18 chr22 GO:0016787 Not Cancer Driver No 18 0.096 0 0 0.0 0
DUSP19 DUSP19 Q8WTR2 Dual specificity protein phosphatase 19 chr2 GO:0016787 Not Cancer Driver No 34 0.157 15 5 0.333 0
DUSP2 DUSP2 Q05923 Dual specificity protein phosphatase 2 chr2 GO:0016787 Not Cancer Driver No 24 0.076 23 3 0.13 0
DUSP21 DUSP21 Q9H596 Dual specificity protein phosphatase 21 chrX GO:0016787 Not Cancer Driver No 49 0.258 0 0 0.0 0
DUSP22_ENST00000344450 DUSP22 Q9NRW4 Dual specificity protein phosphatase 22 chr6 GO:0016787 Not Cancer Driver No 84 0.457 0 0 0.0 0
DUSP23_ENST00000368109 DUSP23 Q9BVJ7 Dual specificity protein phosphatase 23 chr1 GO:0016787 Not Cancer Driver No 6 0.04 13 1 0.077 0
DUSP26 DUSP26 Q9BV47 Dual specificity protein phosphatase 26 chr8 GO:0016787 Not Cancer Driver No 56 0.265 14 6 0.429 0
DUSP27_ENST00000271385 STYXL2 Q5VZP5 Serine/threonine/tyrosine-interacting-like protein 2 chr1 GO:0016787 Not Cancer Driver No 330 0.285 864 257 0.297 0
DUSP28_ENST00000343217 DUSP28 Q4G0W2 Dual specificity phosphatase 28 chr2 GO:0016787 Not Cancer Driver No 11 0.062 55 4 0.073 0
DUSP3 DUSP3 P51452 Dual specificity protein phosphatase 3 chr17 GO:0016787 Not Cancer Driver No 21 0.114 4 1 0.25 0
DUSP4 DUSP4 Q13115 Dual specificity protein phosphatase 4 chr8 GO:0016787 Not Cancer Driver No 43 0.109 63 9 0.143 0
DUSP5 DUSP5 Q16690 Dual specificity protein phosphatase 5 chr10 GO:0016787 Not Cancer Driver No 58 0.151 36 4 0.111 0
DUSP6 DUSP6 Q16828 Dual specificity protein phosphatase 6 chr12 GO:0016787 Not Cancer Driver No 43 0.113 39 3 0.077 4
DUSP7 DUSP7 Q16829 Dual specificity protein phosphatase 7 chr3 GO:0016787 Not Cancer Driver No 40 0.095 139 5 0.036 0
DUSP8_ENST00000331588 DUSP8 Q13202 Dual specificity protein phosphatase 8 chr11 GO:0016787 Not Cancer Driver No 40 0.064 338 11 0.033 0
DUSP9 DUSP9 Q99956 Dual specificity protein phosphatase 9 chrX GO:0016787 Not Cancer Driver No 40 0.104 109 12 0.11 0
DUT DUT P33316 Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial chr15 GO:0016787 Not Cancer Driver No 19 0.075 128 8 0.062 0
DXO_ENST00000375356 DXO O77932 Decapping and exoribonuclease protein chr6 GO:0016787 Not Cancer Driver No 46 0.116 143 17 0.119 0
EDC3 EDC3 Q96F86 Enhancer of mRNA-decapping protein 3 chr15 GO:0016787 Not Cancer Driver No 43 0.085 185 22 0.119 1
EDEM1 EDEM1 Q92611 ER degradation-enhancing alpha-mannosidase-like protein 1 chr3 GO:0016787 Not Cancer Driver No 54 0.082 141 5 0.035 0
EDEM2 EDEM2 Q9BV94 ER degradation-enhancing alpha-mannosidase-like protein 2 chr20 GO:0016787 Not Cancer Driver No 69 0.119 54 3 0.056 0
EDEM3 EDEM3 Q9BZQ6 ER degradation-enhancing alpha-mannosidase-like protein 3 chr1 GO:0016787 Not Cancer Driver No 108 0.116 298 38 0.128 0
EDNRA EDNRA P25101 Endothelin-1 receptor chr4 GO:0016787 Not Cancer Driver No 62 0.145 21 6 0.286 2
EHD2 EHD2 Q9NZN4 EH domain-containing protein 2 chr19 GO:0016787 Compendium Yes 85 0.157 125 12 0.096 0
EIF3F_ENST00000309828 EIF3F O00303 Eukaryotic translation initiation factor 3 subunit F chr11 GO:0016787 Not Cancer Driver No 29 0.081 125 8 0.064 1
EIF3H EIF3H O15372 Eukaryotic translation initiation factor 3 subunit H chr8 GO:0016787 Not Cancer Driver No 37 0.105 109 12 0.11 0
ELAC1 ELAC1 Q9H777 Zinc phosphodiesterase ELAC protein 1 chr18 GO:0016787 Not Cancer Driver No 40 0.11 47 4 0.085 0
ELAC2 ELAC2 Q9BQ52 Zinc phosphodiesterase ELAC protein 2 chr17 GO:0016787 Not Cancer Driver No 86 0.104 208 30 0.144 10
ENDOG ENDOG Q14249 Endonuclease G, mitochondrial chr9 GO:0016787 Not Cancer Driver No 11 0.037 61 1 0.016 0
ENDOV ENDOV Q8N8Q3 Endonuclease V chr17 GO:0016787 Not Cancer Driver No 28 0.099 43 3 0.07 0
ENGASE ENGASE Q8NFI3 Cytosolic endo-beta-N-acetylglucosaminidase chr17 GO:0016787 Not Cancer Driver No 93 0.125 87 8 0.092 0
ENOPH1 ENOPH1 Q9UHY7 Enolase-phosphatase E1 chr4 GO:0016787 Not Cancer Driver No 35 0.134 14 2 0.143 0
ENPEP ENPEP Q07075 Glutamyl aminopeptidase chr4 GO:0016787 Compendium Yes 235 0.246 130 44 0.338 0
ENPP1 ENPP1 P22413 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 chr6 GO:0016787 Not Cancer Driver No 148 0.16 101 5 0.05 33
ENPP2_ENST00000075322 ENPP2 Q13822 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 chr8 GO:0016787 Not Cancer Driver No 168 0.195 81 16 0.198 0
ENPP3_ENST00000357639 ENPP3 O14638 Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 chr6 GO:0016787 Not Cancer Driver No 146 0.167 57 12 0.211 0
ENPP4 ENPP4 Q9Y6X5 Bis(5'-adenosyl)-triphosphatase ENPP4 chr6 GO:0016787 Not Cancer Driver No 79 0.174 20 4 0.2 0
ENPP5 ENPP5 Q9UJA9 Ectonucleotide pyrophosphatase/phosphodiesterase family member 5 chr6 GO:0016787 Not Cancer Driver No 88 0.184 8 1 0.125 0
ENPP6 ENPP6 Q6UWR7 Glycerophosphocholine cholinephosphodiesterase ENPP6 chr4 GO:0016787 Not Cancer Driver No 88 0.2 7 1 0.143 0
ENPP7 ENPP7 Q6UWV6 Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 chr17 GO:0016787 Not Cancer Driver No 102 0.223 65 19 0.292 0
ENTPD1_ENST00000371205 ENTPD1 P49961 Ectonucleoside triphosphate diphosphohydrolase 1 chr10 GO:0016787 Not Cancer Driver No 63 0.124 16 2 0.125 1
ENTPD2 ENTPD2 Q9Y5L3 Ectonucleoside triphosphate diphosphohydrolase 2 chr9 GO:0016787 Not Cancer Driver No 36 0.073 32 0 0.0 0
ENTPD3 ENTPD3 O75355 Ectonucleoside triphosphate diphosphohydrolase 3 chr3 GO:0016787 Not Cancer Driver No 64 0.121 14 2 0.143 0
ENTPD4 ENTPD4 Q9Y227 Ectonucleoside triphosphate diphosphohydrolase 4 chr8 GO:0016787 Not Cancer Driver No 67 0.109 26 2 0.077 0
ENTPD5 ENTPD5 O75356 Nucleoside diphosphate phosphatase ENTPD5 chr14 GO:0016787 Not Cancer Driver No 41 0.096 6 1 0.167 0
ENTPD6 ENTPD6 O75354 Ectonucleoside triphosphate diphosphohydrolase 6 chr20 GO:0016787 Not Cancer Driver No 68 0.14 41 6 0.146 0
ENTPD7 ENTPD7 Q9NQZ7 Ectonucleoside triphosphate diphosphohydrolase 7 chr10 GO:0016787 Not Cancer Driver No 90 0.149 26 3 0.115 0
ENTPD8 ENTPD8 Q5MY95 Ectonucleoside triphosphate diphosphohydrolase 8 chr9 GO:0016787 Not Cancer Driver No 46 0.093 5 0 0.0 0
EP400 EP400 Q96L91 E1A-binding protein p400 chr12 GO:0016787 Not Cancer Driver No 397 0.126 2064 234 0.113 0
EPHX1_ENST00000366837 EPHX1 P07099 Epoxide hydrolase 1 chr1 GO:0016787 Not Cancer Driver No 75 0.165 7 3 0.429 0
EPHX2 EPHX2 P34913 Bifunctional epoxide hydrolase 2 chr8 GO:0016787 Not Cancer Driver No 78 0.141 26 3 0.115 0
EPHX3_ENST00000602233 EPHX3 Q9H6B9 Epoxide hydrolase 3 chr19 GO:0016787 Not Cancer Driver No 40 0.111 0 0 0.0 0
EPHX4 EPHX4 Q8IUS5 Epoxide hydrolase 4 chr1 GO:0016787 Not Cancer Driver No 60 0.166 1 0 0.0 0
ERAP1_ENST00000443439 ERAP1 Q9NZ08 Endoplasmic reticulum aminopeptidase 1 chr5 GO:0016787 Not Cancer Driver No 78 0.083 70 2 0.029 0
ERAP2 ERAP2 Q6P179 Endoplasmic reticulum aminopeptidase 2 chr5 GO:0016787 Not Cancer Driver No 97 0.101 23 4 0.174 0
ERAS_ENST00000636362 ERAS Q7Z444 GTPase ERas chrX GO:0016787 Not Cancer Driver No 42 0.18 29 4 0.138 0
ERCC1_ENST00000589165 ERCC1 P07992 DNA excision repair protein ERCC-1 chr19 GO:0016787 Not Cancer Driver No 42 0.141 105 14 0.133 1
ERCC4 ERCC4 Q92889 DNA repair endonuclease XPF chr16 GO:0016787 Census Yes 120 0.131 225 27 0.12 15
ERMP1 ERMP1 Q7Z2K6 Endoplasmic reticulum metallopeptidase 1 chr9 GO:0016787 Not Cancer Driver No 80 0.088 93 4 0.043 0
ESD ESD P10768 S-formylglutathione hydrolase chr13 GO:0016787 Not Cancer Driver No 33 0.117 4 0 0.0 0
EXD2 EXD2 Q9NVH0 Exonuclease 3'-5' domain-containing protein 2 chr14 GO:0016787 Not Cancer Driver No 58 0.093 176 15 0.085 0
EXO1_ENST00000348581 EXO1 Q9UQ84 Exonuclease 1 chr1 GO:0016787 Not Cancer Driver No 123 0.145 472 76 0.161 0
EXO5_ENST00000358527 EXO5 Q9H790 Exonuclease V chr1 GO:0016787 Not Cancer Driver No 39 0.105 36 3 0.083 0
EXOG EXOG Q9Y2C4 Nuclease EXOG, mitochondrial chr3 GO:0016787 Not Cancer Driver No 42 0.114 52 1 0.019 0
EXOSC1 EXOSC1 Q9Y3B2 Exosome complex component CSL4 chr10 GO:0016787 Not Cancer Driver No 14 0.072 14 2 0.143 1
EXOSC10 EXOSC10 Q01780 Exosome component 10 chr1 GO:0016787 Not Cancer Driver No 87 0.098 375 35 0.093 0
EXOSC2 EXOSC2 Q13868 Exosome complex component RRP4 chr9 GO:0016787 Not Cancer Driver No 21 0.072 47 6 0.128 2
EXOSC3 EXOSC3 Q9NQT5 Exosome complex component RRP40 chr9 GO:0016787 Not Cancer Driver No 18 0.065 54 2 0.037 4
EXOSC4 EXOSC4 Q9NPD3 Exosome complex component RRP41 chr8 GO:0016787 Not Cancer Driver No 34 0.139 23 0 0.0 0
EXOSC5 EXOSC5 Q9NQT4 Exosome complex component RRP46 chr19 GO:0016787 Not Cancer Driver No 43 0.183 31 3 0.097 0
EXOSC6 EXOSC6 Q5RKV6 Exosome complex component MTR3 chr16 GO:0016787 Not Cancer Driver No 3 0.011 102 0 0.0 0
EXOSC7 EXOSC7 Q15024 Exosome complex component RRP42 chr3 GO:0016787 Not Cancer Driver No 41 0.141 8 1 0.125 0
EXOSC8 EXOSC8 Q96B26 Exosome complex component RRP43 chr13 GO:0016787 Not Cancer Driver No 20 0.072 28 1 0.036 2
EXOSC9_ENST00000243498 EXOSC9 Q06265 Exosome complex component RRP45 chr4 GO:0016787 Not Cancer Driver No 58 0.132 154 18 0.117 1
F11 F11 P03951 Coagulation factor XI chr4 GO:0016787 Not Cancer Driver No 108 0.173 1 0 0.0 58
F2RL2 F2RL2 O00254 Proteinase-activated receptor 3 chr5 GO:0016787 Not Cancer Driver No 54 0.144 0 0 0.0 0
FAAH FAAH O00519 Fatty-acid amide hydrolase 1 chr1 GO:0016787 Not Cancer Driver No 63 0.109 50 14 0.28 0
FAAH2 FAAH2 Q6GMR7 Fatty-acid amide hydrolase 2 chrX GO:0016787 Not Cancer Driver No 111 0.209 18 8 0.444 0
FAHD1_ENST00000427358 FAHD1 Q6P587 Acylpyruvase FAHD1, mitochondrial chr16 GO:0016787 Not Cancer Driver No 15 0.067 12 0 0.0 0
FAHD2A FAHD2A Q96GK7 Fumarylacetoacetate hydrolase domain-containing protein 2A chr2 GO:0016787 Not Cancer Driver No 39 0.124 8 2 0.25 0
FAHD2B FAHD2B Q6P2I3 Fumarylacetoacetate hydrolase domain-containing protein 2B chr2 GO:0016787 Not Cancer Driver No 44 0.14 4 3 0.75 0
FAH_ENST00000561421 FAH P16930 Fumarylacetoacetase chr15 GO:0016787 Not Cancer Driver No 50 0.119 41 10 0.244 20
FAM83B FAM83B Q5T0W9 Protein FAM83B chr6 GO:0016787 Not Cancer Driver No 314 0.311 684 219 0.32 0
FAN1 FAN1 Q9Y2M0 Fanconi-associated nuclease 1 chr15 GO:0016787 Not Cancer Driver No 124 0.122 212 27 0.127 4
FAP FAP Q12884 Prolyl endopeptidase FAP chr2 GO:0016787 Not Cancer Driver No 158 0.208 6 2 0.333 0
FASN FASN P49327 Fatty acid synthase chr17 GO:0016787 Not Cancer Driver No 291 0.116 309 42 0.136 0
FBP1_ENST00000375326 FBP1 P09467 Fructose-1,6-bisphosphatase 1 chr9 GO:0016787 Not Cancer Driver No 33 0.098 19 0 0.0 4
FBP2 FBP2 O00757 Fructose-1,6-bisphosphatase isozyme 2 chr9 GO:0016787 Not Cancer Driver No 54 0.159 15 3 0.2 0
FEN1 FEN1 P39748 Flap endonuclease 1 chr11 GO:0016787 Census Yes 35 0.092 111 11 0.099 0
FHIT_ENST00000492590 FHIT P49789 Bis(5'-adenosyl)-triphosphatase chr3 GO:0016787 Census, Compendium Yes 35 0.238 45 9 0.2 0
FICD FICD Q9BVA6 Protein adenylyltransferase FICD chr12 GO:0016787 Not Cancer Driver No 46 0.1 42 3 0.071 0
FIG4 FIG4 Q92562 Polyphosphoinositide phosphatase chr6 GO:0016787 Not Cancer Driver No 114 0.126 177 26 0.147 7
FIGNL1 FIGNL1 Q6PIW4 Fidgetin-like protein 1 chr7 GO:0016787 Not Cancer Driver No 75 0.111 224 23 0.103 0
FITM2 FITM2 Q8N6M3 Acyl-coenzyme A diphosphatase FITM2 chr20 GO:0016787 Not Cancer Driver No 28 0.107 0 0 0.0 1
FOLH1 FOLH1 Q04609 Glutamate carboxypeptidase 2 chr11 GO:0016787 Not Cancer Driver No 200 0.267 43 13 0.302 0
FUCA1 FUCA1 P04066 Tissue alpha-L-fucosidase chr1 GO:0016787 Not Cancer Driver No 42 0.09 11 1 0.091 3
FUCA2 FUCA2 Q9BTY2 Plasma alpha-L-fucosidase chr6 GO:0016787 Not Cancer Driver No 50 0.107 2 0 0.0 0
G6PC G6PC1 P35575 Glucose-6-phosphatase catalytic subunit 1 chr17 GO:0016787 Not Cancer Driver No 67 0.188 0 0 0.0 54
G6PC2 G6PC2 Q9NQR9 Glucose-6-phosphatase 2 chr2 GO:0016787 Not Cancer Driver No 68 0.192 0 0 0.0 0
G6PC3 G6PC3 Q9BUM1 Glucose-6-phosphatase 3 chr17 GO:0016787 Not Cancer Driver No 21 0.061 2 0 0.0 21
GAA_ENST00000390015 GAA P10253 Lysosomal alpha-glucosidase chr17 GO:0016787 Not Cancer Driver No 101 0.106 147 18 0.122 131
GALC GALC P54803 Galactocerebrosidase chr14 GO:0016787 Not Cancer Driver No 88 0.128 21 2 0.095 44
GALNS GALNS P34059 N-acetylgalactosamine-6-sulfatase chr16 GO:0016787 Not Cancer Driver No 65 0.125 37 3 0.081 126
GANAB_ENST00000356638 GANAB Q14697 Neutral alpha-glucosidase AB chr11 GO:0016787 Not Cancer Driver No 129 0.137 132 20 0.152 3
GANC GANC Q8TET4 Neutral alpha-glucosidase C chr15 GO:0016787 Not Cancer Driver No 104 0.114 61 3 0.049 0
GARS GARS1 P41250 Glycine--tRNA ligase chr7 GO:0016787 Not Cancer Driver No 61 0.083 75 9 0.12 17
GBA2 GBA2 Q9HCG7 Non-lysosomal glucosylceramidase chr9 GO:0016787 Not Cancer Driver No 96 0.104 157 12 0.076 3
GBA3 GBA3 Q9H227 Cytosolic beta-glucosidase chr4 GO:0016787 Not Cancer Driver No 118 0.252 18 6 0.333 0
GBA_ENST00000368373 GBA P04062 Lysosomal acid glucosylceramidase chr1 GO:0016787 Not Cancer Driver No 74 0.138 38 5 0.132 171
GCH1_ENST00000622544 GCH1 P30793 GTP cyclohydrolase 1 chr14 GO:0016787 Not Cancer Driver No 20 0.08 99 5 0.051 38
GDA_ENST00000358399 GDA Q9Y2T3 Guanine deaminase chr9 GO:0016787 Not Cancer Driver No 86 0.189 22 7 0.318 0
GDE1 GDE1 Q9NZC3 Glycerophosphodiester phosphodiesterase 1 chr16 GO:0016787 Not Cancer Driver No 36 0.109 37 1 0.027 0
GDPD2_ENST00000374382 GDPD2 Q9HCC8 Glycerophosphoinositol inositolphosphodiesterase GDPD2 chrX GO:0016787 Not Cancer Driver No 96 0.178 43 15 0.349 0
GDPD4_ENST00000376217 GDPD4 Q6W3E5 Glycerophosphodiester phosphodiesterase domain-containing protein 4 chr11 GO:0016787 Not Cancer Driver No 89 0.143 114 8 0.07 0
GDPD5_ENST00000529721 GDPD5 Q8WTR4 Glycerophosphodiester phosphodiesterase domain-containing protein 5 chr11 GO:0016787 Not Cancer Driver No 74 0.122 65 11 0.169 0
GDPGP1 GDPGP1 Q6ZNW5 GDP-D-glucose phosphorylase 1 chr15 GO:0016787 Not Cancer Driver No 44 0.114 83 9 0.108 0
GEN1_ENST00000381254 GEN1 Q17RS7 Flap endonuclease GEN homolog 1 chr2 GO:0016787 Not Cancer Driver No 109 0.12 339 52 0.153 0
GGH GGH Q92820 Gamma-glutamyl hydrolase chr8 GO:0016787 Not Cancer Driver No 46 0.145 5 0 0.0 0
GGT1_ENST00000248923 GGT1 P19440 Glutathione hydrolase 1 proenzyme chr22 GO:0016787 Not Cancer Driver No 83 0.146 88 14 0.159 0
GGT2 GGT2P P36268 Inactive glutathione hydrolase 2 chr22 GO:0016787 Not Cancer Driver No 5 0.009 48 1 0.021 0
GGT5_ENST00000327365 GGT5 P36269 Glutathione hydrolase 5 proenzyme chr22 GO:0016787 Not Cancer Driver No 99 0.169 122 27 0.221 0
GGT6_ENST00000574154 GGT6 Q6P531 Glutathione hydrolase 6 chr17 GO:0016787 Not Cancer Driver No 51 0.103 211 32 0.152 0
GGT7 GGT7 Q9UJ14 Glutathione hydrolase 7 chr20 GO:0016787 Not Cancer Driver No 77 0.116 170 14 0.082 0
GGTLC1_ENST00000278765 GGTLC1 Q9BX51 Glutathione hydrolase light chain 1 chr20 GO:0016787 Not Cancer Driver No 63 0.28 81 17 0.21 0
GGTLC2 GGTLC2 Q14390 Glutathione hydrolase light chain 2 chr22 GO:0016787 Not Cancer Driver No 25 0.115 119 11 0.092 0
GLA GLA P06280 Alpha-galactosidase A chrX GO:0016787 Not Cancer Driver No 71 0.166 7 2 0.286 180
GLB1 GLB1 P16278 Beta-galactosidase chr3 GO:0016787 Not Cancer Driver No 72 0.106 54 6 0.111 99
GLB1L GLB1L Q6UWU2 Beta-galactosidase-1-like protein chr2 GO:0016787 Not Cancer Driver No 71 0.109 11 2 0.182 0
GLB1L2_ENST00000339772 GLB1L2 Q8IW92 Beta-galactosidase-1-like protein 2 chr11 GO:0016787 Not Cancer Driver No 103 0.162 8 1 0.125 0
GLB1L3 GLB1L3 Q8NCI6 Beta-galactosidase-1-like protein 3 chr11 GO:0016787 Not Cancer Driver No 119 0.182 32 2 0.062 0
GLS GLS O94925 Glutaminase kidney isoform, mitochondrial chr2 GO:0016787 Not Cancer Driver No 71 0.106 187 9 0.048 3
GLS2 GLS2 Q9UI32 Glutaminase liver isoform, mitochondrial chr12 GO:0016787 Not Cancer Driver No 57 0.095 108 9 0.083 0
GM2A GM2A P17900 Ganglioside GM2 activator chr5 GO:0016787 Not Cancer Driver No 26 0.135 0 0 0.0 2
GNPDA1_ENST00000311337 GNPDA1 P46926 Glucosamine-6-phosphate isomerase 1 chr5 GO:0016787 Not Cancer Driver No 23 0.08 17 3 0.176 0
GNPDA2 GNPDA2 Q8TDQ7 Glucosamine-6-phosphate isomerase 2 chr4 GO:0016787 Not Cancer Driver No 32 0.116 0 0 0.0 0
GNS GNS P15586 N-acetylglucosamine-6-sulfatase chr12 GO:0016787 Not Cancer Driver No 48 0.087 22 0 0.0 3
GPAA1 GPAA1 O43292 Glycosylphosphatidylinositol anchor attachment 1 protein chr8 GO:0016787 Not Cancer Driver No 55 0.089 20 3 0.15 5
GPCPD1 GPCPD1 Q9NPB8 Glycerophosphocholine phosphodiesterase GPCPD1 chr20 GO:0016787 Not Cancer Driver No 69 0.103 60 8 0.133 0
GPLD1 GPLD1 P80108 Phosphatidylinositol-glycan-specific phospholipase D chr6 GO:0016787 Not Cancer Driver No 153 0.182 36 9 0.25 0
GUSB GUSB P08236 Beta-glucuronidase chr7 GO:0016787 Not Cancer Driver No 93 0.143 11 0 0.0 36
H6PD_ENST00000377403 H6PD O95479 GDH/6PGL endoplasmic bifunctional protein chr1 GO:0016787 Not Cancer Driver No 96 0.121 39 3 0.077 2
HAGH HAGH Q16775 Hydroxyacylglutathione hydrolase, mitochondrial chr16 GO:0016787 Not Cancer Driver No 26 0.084 41 1 0.024 0
HAGHL_ENST00000341413 HAGHL Q6PII5 Hydroxyacylglutathione hydrolase-like protein chr16 GO:0016787 Not Cancer Driver No 17 0.059 26 3 0.115 0
HDAC1 HDAC1 Q13547 Histone deacetylase 1 chr1 GO:0016787 Not Cancer Driver No 47 0.098 135 10 0.074 0
HDAC10 HDAC10 Q969S8 Polyamine deacetylase HDAC10 chr22 GO:0016787 Not Cancer Driver No 67 0.1 121 11 0.091 0
HDAC11 HDAC11 Q96DB2 Histone deacetylase 11 chr3 GO:0016787 Not Cancer Driver No 57 0.164 18 8 0.444 0
HDAC2 HDAC2 Q92769 Histone deacetylase 2 chr6 GO:0016787 Not Cancer Driver No 46 0.094 145 14 0.097 0
HDAC3 HDAC3 O15379 Histone deacetylase 3 chr5 GO:0016787 Not Cancer Driver No 65 0.152 61 8 0.131 0
HDAC4 HDAC4 P56524 Histone deacetylase 4 chr2 GO:0016787 Not Cancer Driver No 182 0.168 749 132 0.176 0
HDAC5_ENST00000586802 HDAC5 Q9UQL6 Histone deacetylase 5 chr17 GO:0016787 Not Cancer Driver No 118 0.105 718 73 0.102 0
HDAC6_ENST00000426196 HDAC6 Q9UBN7 Histone deacetylase 6 chrX GO:0016787 Not Cancer Driver No 178 0.147 409 59 0.144 0
HDAC7_ENST00000427332 HDAC7 Q8WUI4 Histone deacetylase 7 chr12 GO:0016787 Not Cancer Driver No 91 0.096 570 50 0.088 0
HDAC8 HDAC8 Q9BY41 Histone deacetylase 8 chrX GO:0016787 Not Cancer Driver No 54 0.143 32 4 0.125 4
HDAC9_ENST00000432645 HDAC9 Q9UKV0 Histone deacetylase 9 chr7 GO:0016787 Not Cancer Driver No 286 0.283 631 178 0.282 0
HDDC2 HDDC2 Q7Z4H3 5'-deoxynucleotidase HDDC2 chr6 GO:0016787 Not Cancer Driver No 26 0.127 74 7 0.095 0
HDDC3_ENST00000646620 HDDC3 Q8N4P3 Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1 chr15 GO:0016787 Not Cancer Driver No 13 0.073 76 9 0.118 0
HELLS_ENST00000348459 HELLS Q9NRZ9 Lymphoid-specific helicase chr10 GO:0016787 Not Cancer Driver No 78 0.093 227 25 0.11 0
HELZ_ENST00000358691 HELZ P42694 Probable helicase with zinc finger domain chr17 GO:0016787 Not Cancer Driver No 234 0.12 873 110 0.126 0
HEXA_ENST00000268097 HEXA P06865 Beta-hexosaminidase subunit alpha chr15 GO:0016787 Not Cancer Driver No 59 0.112 5 1 0.2 49
HEXB HEXB P07686 Beta-hexosaminidase subunit beta chr5 GO:0016787 Not Cancer Driver No 45 0.081 0 0 0.0 9
HEXD_ENST00000327949 HEXD Q8WVB3 Hexosaminidase D chr17 GO:0016787 Not Cancer Driver No 60 0.123 40 0 0.0 0
HIBCH HIBCH Q6NVY1 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial chr2 GO:0016787 Not Cancer Driver No 42 0.109 26 0 0.0 1
HINT1 HINT1 P49773 Adenosine 5'-monophosphoramidase HINT1 chr5 GO:0016787 Not Cancer Driver No 11 0.087 6 0 0.0 6
HINT2 HINT2 Q9BX68 Adenosine 5'-monophosphoramidase HINT2 chr9 GO:0016787 Not Cancer Driver No 10 0.061 29 2 0.069 0
HINT3 HINT3 Q9NQE9 Adenosine 5'-monophosphoramidase HINT3 chr6 GO:0016787 Not Cancer Driver No 16 0.088 31 3 0.097 0
HM13_ENST00000340852 HM13 Q8TCT9 Minor histocompatibility antigen H13 chr20 GO:0016787 Not Cancer Driver No 42 0.111 61 6 0.098 0
HMOX1 HMOX1 P09601 Heme oxygenase 1 chr22 GO:0016787 Not Cancer Driver No 46 0.16 81 13 0.16 0
HPN_ENST00000392226 HPN P05981 Serine protease hepsin chr19 GO:0016787 Not Cancer Driver No 60 0.144 12 0 0.0 0
HPSE HPSE Q9Y251 Heparanase chr4 GO:0016787 Not Cancer Driver No 90 0.166 16 2 0.125 0
HPSE2 HPSE2 Q8WWQ2 Inactive heparanase-2 chr10 GO:0016787 Not Cancer Driver No 123 0.208 42 20 0.476 0
HRAS HRAS P01112 GTPase HRas chr11 GO:0016787 Census, Compendium Yes 107 0.566 16 4 0.25 18
HRASLS2 PLAAT2 Q9NWW9 Phospholipase A and acyltransferase 2 chr11 GO:0016787 Not Cancer Driver No 24 0.148 16 2 0.125 0
HRASLS5 PLAAT5 Q96KN8 Phospholipase A and acyltransferase 5 chr11 GO:0016787 Not Cancer Driver No 41 0.147 127 12 0.094 0
HYAL1_ENST00000395144 HYAL1 Q12794 Hyaluronidase-1 chr3 GO:0016787 Not Cancer Driver No 47 0.108 9 0 0.0 1
HYAL2_ENST00000357750 HYAL2 Q12891 Hyaluronidase-2 chr3 GO:0016787 Not Cancer Driver No 52 0.11 8 1 0.125 0
HYAL3 HYAL3 O43820 Hyaluronidase-3 chr3 GO:0016787 Not Cancer Driver No 48 0.115 10 0 0.0 0
HYAL4_ENST00000476325 HYAL4 Q2M3T9 Hyaluronidase-4 chr7 GO:0016787 Not Cancer Driver No 100 0.208 0 0 0.0 0
IAH1 IAH1 Q2TAA2 Isoamyl acetate-hydrolyzing esterase 1 homolog chr2 GO:0016787 Not Cancer Driver No 25 0.101 0 0 0.0 0
IARS IARS1 P41252 Isoleucine--tRNA ligase, cytoplasmic chr9 GO:0016787 Not Cancer Driver No 130 0.103 28 4 0.143 4
IARS2 IARS2 Q9NSE4 Isoleucine--tRNA ligase, mitochondrial chr1 GO:0016787 Not Cancer Driver No 149 0.147 145 22 0.152 0
IDS IDS P22304 Iduronate 2-sulfatase chrX GO:0016787 Not Cancer Driver No 91 0.165 85 13 0.153 126
IDUA IDUA P35475 Alpha-L-iduronidase chr4 GO:0016787 Not Cancer Driver No 46 0.07 101 5 0.05 57
IL18R1_ENST00000233957 IL18R1 Q13478 Interleukin-18 receptor 1 chr2 GO:0016787 Not Cancer Driver No 104 0.192 18 3 0.167 0
IL18RAP IL18RAP O95256 Interleukin-18 receptor accessory protein chr2 GO:0016787 Not Cancer Driver No 145 0.242 20 9 0.45 0
IL1R1 IL1R1 P14778 Interleukin-1 receptor type 1 chr2 GO:0016787 Not Cancer Driver No 77 0.135 59 8 0.136 0
IL1RAPL1 IL1RAPL1 Q9NZN1 Interleukin-1 receptor accessory protein-like 1 chrX GO:0016787 Not Cancer Driver No 205 0.295 77 19 0.247 0
IL1RAPL2 IL1RAPL2 Q9NP60 X-linked interleukin-1 receptor accessory protein-like 2 chrX GO:0016787 Not Cancer Driver No 174 0.254 44 14 0.318 0
IL1RAP_ENST00000447382 IL1RAP Q9NPH3 Interleukin-1 receptor accessory protein chr3 GO:0016787 Not Cancer Driver No 79 0.139 50 11 0.22 0
IL1RL1 IL1RL1 Q01638 Interleukin-1 receptor-like 1 chr2 GO:0016787 Not Cancer Driver No 119 0.214 24 8 0.333 0
IL1RL2 IL1RL2 Q9HB29 Interleukin-1 receptor-like 2 chr2 GO:0016787 Not Cancer Driver No 114 0.198 11 4 0.364 0
IMPA1_ENST00000256108 IMPA1 P29218 Inositol monophosphatase 1 chr8 GO:0016787 Not Cancer Driver No 36 0.13 3 0 0.0 0
IMPA2 IMPA2 O14732 Inositol monophosphatase 2 chr18 GO:0016787 Not Cancer Driver No 44 0.153 21 1 0.048 0
IMPAD1 BPNT2 Q9NX62 Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase chr8 GO:0016787 Not Cancer Driver No 45 0.125 86 10 0.116 2
INPP1 INPP1 P49441 Inositol polyphosphate 1-phosphatase chr2 GO:0016787 Not Cancer Driver No 44 0.11 23 1 0.043 0
INPP4A INPP4A Q96PE3 Inositol polyphosphate-4-phosphatase type I A chr2 GO:0016787 Not Cancer Driver No 114 0.117 153 20 0.131 0
INPP4B_ENST00000513000 INPP4B O15327 Inositol polyphosphate 4-phosphatase type II chr4 GO:0016787 Not Cancer Driver No 145 0.157 191 36 0.188 0
INPP5A INPP5A Q14642 Inositol polyphosphate-5-phosphatase A chr10 GO:0016787 Not Cancer Driver No 59 0.143 7 4 0.571 0
INPP5B_ENST00000373026 INPP5B P32019 Type II inositol 1,4,5-trisphosphate 5-phosphatase chr1 GO:0016787 Not Cancer Driver No 108 0.109 114 11 0.096 0
INPP5D INPP5D Q92835 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 chr2 GO:0016787 Not Cancer Driver No 176 0.148 578 90 0.156 0
INPP5E INPP5E Q9NRR6 Phosphatidylinositol polyphosphate 5-phosphatase type IV chr9 GO:0016787 Not Cancer Driver No 43 0.067 272 16 0.059 15
INPP5F INPP5F Q9Y2H2 Phosphatidylinositide phosphatase SAC2 chr10 GO:0016787 Not Cancer Driver No 138 0.122 394 45 0.114 0
INPP5J INPP5J Q15735 Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A chr22 GO:0016787 Not Cancer Driver No 102 0.101 629 42 0.067 0
INPP5K INPP5K Q9BT40 Inositol polyphosphate 5-phosphatase K chr17 GO:0016787 Not Cancer Driver No 42 0.094 34 2 0.059 7
INPPL1 INPPL1 O15357 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 chr11 GO:0016787 Not Cancer Driver No 174 0.138 566 76 0.134 4
ISG20 ISG20 Q96AZ6 Interferon-stimulated gene 20 kDa protein chr15 GO:0016787 Not Cancer Driver No 20 0.11 6 0 0.0 0
ITPA ITPA Q9BY32 Inosine triphosphate pyrophosphatase chr20 GO:0016787 Not Cancer Driver No 21 0.108 10 1 0.1 1
ITPK1 ITPK1 Q13572 Inositol-tetrakisphosphate 1-kinase chr14 GO:0016787 Not Cancer Driver No 74 0.179 24 1 0.042 0
JMJD7 JMJD7 P0C870 Bifunctional peptidase and (3S)-lysyl hydroxylase JMJD7 chr15 GO:0016787 Not Cancer Driver No 40 0.127 0 0 0.0 0
KDM8_ENST00000286096 KDM8 Q8N371 Bifunctional peptidase and arginyl-hydroxylase JMJD5 chr16 GO:0016787 Not Cancer Driver No 52 0.125 29 6 0.207 0
KIAA0391 PRORP O15091 Mitochondrial ribonuclease P catalytic subunit chr14 GO:0016787 Not Cancer Driver No 62 0.106 60 12 0.2 0
KL KL Q9UEF7 Klotho chr13 GO:0016787 Not Cancer Driver No 175 0.173 104 5 0.048 1
KLK13 KLK13 Q9UKR3 Kallikrein-13 chr19 GO:0016787 Not Cancer Driver No 66 0.238 77 17 0.221 0
KRAS KRAS P01116 GTPase KRas chr12 GO:0016787 Census, Compendium Yes 788 4.169 7 2 0.286 27
KYNU_ENST00000409512 KYNU Q16719 Kynureninase chr2 GO:0016787 Not Cancer Driver No 103 0.222 20 5 0.25 1
LACC1 LACC1 Q8IV20 Purine nucleoside phosphorylase LACC1 chr13 GO:0016787 Not Cancer Driver No 50 0.116 4 0 0.0 1
LAP3 LAP3 P28838 Cytosol aminopeptidase chr4 GO:0016787 Not Cancer Driver No 59 0.114 99 14 0.141 0
LARS LARS1 Q9P2J5 Leucine--tRNA ligase, cytoplasmic chr5 GO:0016787 Not Cancer Driver No 133 0.113 97 10 0.103 1
LARS2_ENST00000645846 LARS2 Q15031 Leucine--tRNA ligase, mitochondrial chr3 GO:0016787 Not Cancer Driver No 74 0.082 80 8 0.1 3
LCAT LCAT P04180 Phosphatidylcholine-sterol acyltransferase chr16 GO:0016787 Not Cancer Driver No 43 0.098 28 2 0.071 34
LCT LCT P09848 Lactase/phlorizin hydrolase chr2 GO:0016787 Not Cancer Driver No 411 0.213 248 60 0.242 2
LHPP LHPP Q9H008 Phospholysine phosphohistidine inorganic pyrophosphate phosphatase chr10 GO:0016787 Not Cancer Driver No 32 0.119 20 1 0.05 0
LIPA LIPA P38571 Lysosomal acid lipase/cholesteryl ester hydrolase chr10 GO:0016787 Not Cancer Driver No 44 0.11 12 1 0.083 4
LIPC_ENST00000356113 LIPC P11150 Hepatic triacylglycerol lipase chr15 GO:0016787 Not Cancer Driver No 91 0.182 17 3 0.176 2
LIPE LIPE Q05469 Hormone-sensitive lipase chr19 GO:0016787 Not Cancer Driver No 123 0.114 496 65 0.131 0
LIPG LIPG Q9Y5X9 Endothelial lipase chr18 GO:0016787 Not Cancer Driver No 90 0.18 59 7 0.119 0
LIPH LIPH Q8WWY8 Lipase member H chr3 GO:0016787 Not Cancer Driver No 71 0.157 32 8 0.25 2
LIPI_ENST00000536861 LIPI Q6XZB0 Lipase member I chr21 GO:0016787 Not Cancer Driver No 142 0.309 5 0 0.0 1
LIPK LIPK Q5VXJ0 Lipase member K chr10 GO:0016787 Not Cancer Driver No 44 0.11 0 0 0.0 0
LIPM LIPM Q5VYY2 Lipase member M chr10 GO:0016787 Not Cancer Driver No 18 0.043 13 0 0.0 0
LIPN LIPN Q5VXI9 Lipase member N chr10 GO:0016787 Not Cancer Driver No 53 0.133 8 1 0.125 0
LNPEP LNPEP Q9UIQ6 Leucyl-cystinyl aminopeptidase chr5 GO:0016787 Not Cancer Driver No 115 0.112 103 8 0.078 0
LONP1 LONP1 P36776 Lon protease homolog, mitochondrial chr19 GO:0016787 Not Cancer Driver No 99 0.103 175 15 0.086 10
LONP2 LONP2 Q86WA8 Lon protease homolog 2, peroxisomal chr16 GO:0016787 Not Cancer Driver No 116 0.136 163 26 0.16 0
LPIN1_ENST00000256720 LPIN1 Q14693 Phosphatidate phosphatase LPIN1 chr2 GO:0016787 Not Cancer Driver No 120 0.135 447 70 0.157 0
LPIN2 LPIN2 Q92539 Phosphatidate phosphatase LPIN2 chr18 GO:0016787 Not Cancer Driver No 113 0.126 455 56 0.123 1
LPIN3_ENST00000373257 LPIN3 Q9BQK8 Phosphatidate phosphatase LPIN3 chr20 GO:0016787 Not Cancer Driver No 91 0.107 472 50 0.106 0
LPL LPL P06858 Lipoprotein lipase chr8 GO:0016787 Not Cancer Driver No 94 0.198 23 3 0.13 70
LTA4H LTA4H P09960 Leukotriene A-4 hydrolase chr12 GO:0016787 Not Cancer Driver No 59 0.097 39 6 0.154 0
LVRN LVRN Q6Q4G3 Aminopeptidase Q chr5 GO:0016787 Not Cancer Driver No 212 0.214 81 20 0.247 0
LYG1 LYG1 Q8N1E2 Lysozyme g-like protein 1 chr2 GO:0016787 Not Cancer Driver No 18 0.093 36 4 0.111 0
LYG2 LYG2 Q86SG7 Lysozyme g-like protein 2 chr2 GO:0016787 Not Cancer Driver No 38 0.179 1 1 1.0 0
LYPLA1 LYPLA1 O75608 Acyl-protein thioesterase 1 chr8 GO:0016787 Not Cancer Driver No 19 0.083 12 2 0.167 0
LYPLA2 LYPLA2 O95372 Acyl-protein thioesterase 2 chr1 GO:0016787 Not Cancer Driver No 22 0.095 13 2 0.154 0
LYPLAL1 LYPLAL1 Q5VWZ2 Lysophospholipase-like protein 1 chr1 GO:0016787 Not Cancer Driver No 30 0.127 2 0 0.0 0
LYZ LYZ P61626 Lysozyme C chr12 GO:0016787 Not Cancer Driver No 26 0.176 0 0 0.0 2
LYZL4 LYZL4 Q96KX0 Lysozyme-like protein 4 chr3 GO:0016787 Not Cancer Driver No 25 0.171 0 0 0.0 0
MACROD1 MACROD1 Q9BQ69 ADP-ribose glycohydrolase MACROD1 chr11 GO:0016787 Not Cancer Driver No 24 0.074 45 1 0.022 0
MACROD2 MACROD2 A1Z1Q3 ADP-ribose glycohydrolase MACROD2 chr20 GO:0016787 Not Cancer Driver No 106 0.249 231 60 0.26 0
MAN1A1 MAN1A1 P33908 Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA chr6 GO:0016787 Not Cancer Driver No 118 0.181 134 23 0.172 0
MAN1A2 MAN1A2 O60476 Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB chr1 GO:0016787 Not Cancer Driver No 74 0.115 128 18 0.141 0
MAN1B1 MAN1B1 Q9UKM7 Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase chr9 GO:0016787 Not Cancer Driver No 74 0.106 172 22 0.128 2
MAN1C1 MAN1C1 Q9NR34 Mannosyl-oligosaccharide 1,2-alpha-mannosidase IC chr1 GO:0016787 Not Cancer Driver No 83 0.132 130 20 0.154 0
MAN2A1 MAN2A1 Q16706 Alpha-mannosidase 2 chr5 GO:0016787 Not Cancer Driver No 165 0.144 83 9 0.108 0
MAN2A2 MAN2A2 P49641 Alpha-mannosidase 2x chr15 GO:0016787 Not Cancer Driver No 122 0.106 53 6 0.113 0
MAN2B1 MAN2B1 O00754 Lysosomal alpha-mannosidase chr19 GO:0016787 Not Cancer Driver No 139 0.137 145 21 0.145 40
MAN2B2 MAN2B2 Q9Y2E5 Epididymis-specific alpha-mannosidase chr4 GO:0016787 Not Cancer Driver No 135 0.134 153 23 0.15 0
MAN2C1_ENST00000267978 MAN2C1 Q9NTJ4 Alpha-mannosidase 2C1 chr15 GO:0016787 Not Cancer Driver No 120 0.115 72 4 0.056 0
MANBA MANBA O00462 Beta-mannosidase chr4 GO:0016787 Not Cancer Driver No 108 0.123 10 0 0.0 3
MANEA MANEA Q5SRI9 Glycoprotein endo-alpha-1,2-mannosidase chr6 GO:0016787 Not Cancer Driver No 91 0.197 80 14 0.175 0
MANEAL MANEAL Q5VSG8 Glycoprotein endo-alpha-1,2-mannosidase-like protein chr1 GO:0016787 Not Cancer Driver No 34 0.074 136 9 0.066 0
MBD4 MBD4 O95243 Methyl-CpG-binding domain protein 4 chr3 GO:0016787 Not Cancer Driver No 61 0.105 268 27 0.101 0
MBLAC2 MBLAC2 Q68D91 Acyl-coenzyme A thioesterase MBLAC2 chr5 GO:0016787 Not Cancer Driver No 16 0.057 1 0 0.0 0
MDP1 MDP1 Q86V88 Magnesium-dependent phosphatase 1 chr14 GO:0016787 Not Cancer Driver No 25 0.142 35 8 0.229 0
MEIOB_ENST00000397344 MEIOB Q8N635 Meiosis-specific with OB domain-containing protein chr16 GO:0016787 Not Cancer Driver No 37 0.084 21 2 0.095 1
MEST MEST Q5EB52 Mesoderm-specific transcript homolog protein chr7 GO:0016787 Not Cancer Driver No 34 0.101 0 0 0.0 0
METAP1 METAP1 P53582 Methionine aminopeptidase 1 chr4 GO:0016787 Not Cancer Driver No 37 0.096 61 3 0.049 0
METAP1D METAP1D Q6UB28 Methionine aminopeptidase 1D, mitochondrial chr2 GO:0016787 Not Cancer Driver No 40 0.119 30 5 0.167 0
METAP2 METAP2 P50579 Methionine aminopeptidase 2 chr12 GO:0016787 Not Cancer Driver No 54 0.113 176 19 0.108 0
MGAM2 MGAM2 Q2M2H8 Probable maltase-glucoamylase 2 chr7 GO:0016787 Not Cancer Driver No 62 0.025 723 6 0.008 0
MGAM_ENST00000475668 MGAM O43451 Maltase-glucoamylase chr7 GO:0016787 Not Cancer Driver No 708 0.257 315 94 0.298 0
MGME1 MGME1 Q9BQP7 Mitochondrial genome maintenance exonuclease 1 chr20 GO:0016787 Not Cancer Driver No 33 0.096 95 7 0.074 1
MINDY1_ENST00000622754 MINDY1 Q8N5J2 Ubiquitin carboxyl-terminal hydrolase MINDY-1 chr1 GO:0016787 Not Cancer Driver No 61 0.13 219 33 0.151 0
MINDY2 MINDY2 Q8NBR6 Ubiquitin carboxyl-terminal hydrolase MINDY-2 chr15 GO:0016787 Not Cancer Driver No 53 0.085 372 34 0.091 0
MINDY3 MINDY3 Q9H8M7 Ubiquitin carboxyl-terminal hydrolase MINDY-3 chr10 GO:0016787 Not Cancer Driver No 73 0.164 17 2 0.118 0
MINDY4 MINDY4 Q4G0A6 Probable ubiquitin carboxyl-terminal hydrolase MINDY-4 chr7 GO:0016787 Not Cancer Driver No 102 0.135 307 39 0.127 0
MINDY4B MINDY4B A8MYZ0 Inactive ubiquitin carboxyl-terminal hydrolase MINDY-4B chr3 GO:0016787 Not Cancer Driver No 1 0.002 90 0 0.0 0
MINPP1 MINPP1 Q9UNW1 Multiple inositol polyphosphate phosphatase 1 chr10 GO:0016787 Not Cancer Driver No 52 0.107 46 2 0.043 2
MME_ENST00000492661 MME P08473 Neprilysin chr3 GO:0016787 Not Cancer Driver No 189 0.252 40 17 0.425 4
MMP14 MMP14 P50281 Matrix metalloproteinase-14 chr14 GO:0016787 Not Cancer Driver No 64 0.11 118 11 0.093 1
MMP15 MMP15 P51511 Matrix metalloproteinase-15 chr16 GO:0016787 Not Cancer Driver No 78 0.117 205 23 0.112 0
MMP16 MMP16 P51512 Matrix metalloproteinase-16 chr8 GO:0016787 Not Cancer Driver No 235 0.387 168 61 0.363 0
MMP17 MMP17 Q9ULZ9 Matrix metalloproteinase-17 chr12 GO:0016787 Not Cancer Driver No 93 0.154 241 26 0.108 0
MOGS MOGS Q13724 Mannosyl-oligosaccharide glucosidase chr2 GO:0016787 Not Cancer Driver No 105 0.125 200 29 0.145 2
MPG MPG P29372 DNA-3-methyladenine glycosylase chr16 GO:0016787 Not Cancer Driver No 35 0.117 141 21 0.149 0
MPND_ENST00000262966 MPND Q8N594 MPN domain-containing protein chr19 GO:0016787 Not Cancer Driver No 45 0.096 168 8 0.048 0
MPPE1 MPPE1 Q53F39 Metallophosphoesterase 1 chr18 GO:0016787 Not Cancer Driver No 39 0.098 27 5 0.185 0
MPPED1_ENST00000443721 MPPED1 O15442 Metallophosphoesterase domain-containing protein 1 chr22 GO:0016787 Not Cancer Driver No 79 0.242 26 15 0.577 0
MRAS_ENST00000423968 MRAS O14807 Ras-related protein M-Ras chr3 GO:0016787 Not Cancer Driver No 27 0.13 50 13 0.26 3
MRE11 MRE11 P49959 Double-strand break repair protein MRE11 chr11 GO:0016787 Not Cancer Driver No 84 0.119 292 35 0.12 1
MRPL44 MRPL44 Q9H9J2 39S ribosomal protein L44, mitochondrial chr2 GO:0016787 Not Cancer Driver No 37 0.111 45 2 0.044 1
MRPL58 MRPL58 Q14197 Peptidyl-tRNA hydrolase ICT1, mitochondrial chr17 GO:0016787 Not Cancer Driver No 28 0.136 105 13 0.124 0
MTHFD1 MTHFD1 P11586 C-1-tetrahydrofolate synthase, cytoplasmic chr14 GO:0016787 Not Cancer Driver No 103 0.11 129 11 0.085 6
MTHFD2 MTHFD2 P13995 Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial chr2 GO:0016787 Not Cancer Driver No 39 0.111 39 3 0.077 0
MTHFD2L MTHFD2L Q9H903 Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, mitochondrial chr4 GO:0016787 Not Cancer Driver No 45 0.13 59 6 0.102 0
MTM1 MTM1 Q13496 Myotubularin chrX GO:0016787 Not Cancer Driver No 112 0.186 79 9 0.114 57
MTMR10 MTMR10 Q9NXD2 Myotubularin-related protein 10 chr15 GO:0016787 Not Cancer Driver No 79 0.102 98 7 0.071 0
MTMR11 MTMR11 A4FU01 Myotubularin-related protein 11 chr1 GO:0016787 Not Cancer Driver No 108 0.152 147 17 0.116 0
MTMR12 MTMR12 Q9C0I1 Myotubularin-related protein 12 chr5 GO:0016787 Not Cancer Driver No 105 0.141 130 16 0.123 0
MTMR14 MTMR14 Q8NCE2 Myotubularin-related protein 14 chr3 GO:0016787 Not Cancer Driver No 58 0.089 150 8 0.053 2
MTMR1_ENST00000370390 MTMR1 Q13613 Myotubularin-related protein 1 chrX GO:0016787 Not Cancer Driver No 114 0.171 146 21 0.144 0
MTMR2 MTMR2 Q13614 Myotubularin-related protein 2 chr11 GO:0016787 Not Cancer Driver No 70 0.109 140 16 0.114 1
MTMR3 MTMR3 Q13615 Myotubularin-related protein 3 chr22 GO:0016787 Not Cancer Driver No 130 0.109 501 66 0.132 0
MTMR4 MTMR4 Q9NYA4 Myotubularin-related protein 4 chr17 GO:0016787 Not Cancer Driver No 147 0.123 474 59 0.124 0
MTMR6 MTMR6 Q9Y217 Myotubularin-related protein 6 chr13 GO:0016787 Not Cancer Driver No 87 0.14 68 16 0.235 0
MTMR7 MTMR7 Q9Y216 Myotubularin-related protein 7 chr8 GO:0016787 Not Cancer Driver No 98 0.148 160 26 0.163 0
MTMR8 MTMR8 Q96EF0 Myotubularin-related protein 8 chrX GO:0016787 Not Cancer Driver No 140 0.199 55 8 0.145 0
MTMR9 MTMR9 Q96QG7 Myotubularin-related protein 9 chr8 GO:0016787 Not Cancer Driver No 60 0.109 45 7 0.156 0
MUS81 MUS81 Q96NY9 Crossover junction endonuclease MUS81 chr11 GO:0016787 Not Cancer Driver No 67 0.122 232 38 0.164 0
MUTYH MUTYH Q9UIF7 Adenine DNA glycosylase chr1 GO:0016787 Census Yes 90 0.165 198 29 0.146 23
MYD88_ENST00000396334 MYD88 Q99836 Myeloid differentiation primary response protein MyD88 chr3 GO:0016787 Census, Compendium Yes 37 0.125 47 1 0.021 2
MYH3 MYH3 P11055 Myosin-3 chr17 GO:0016787 Not Cancer Driver No 312 0.161 967 179 0.185 14
MYH6 MYH6 P13533 Myosin-6 chr14 GO:0016787 Not Cancer Driver No 392 0.202 1112 238 0.214 7
MYH8 MYH8 P13535 Myosin-8 chr17 GO:0016787 Not Cancer Driver No 498 0.257 1086 315 0.29 2
MYSM1 MYSM1 Q5VVJ2 Deubiquitinase MYSM1 chr1 GO:0016787 Not Cancer Driver No 78 0.094 345 26 0.075 1
NAAA NAAA Q02083 N-acylethanolamine-hydrolyzing acid amidase chr4 GO:0016787 Not Cancer Driver No 42 0.117 43 3 0.07 0
NAALAD2 NAALAD2 Q9Y3Q0 N-acetylated-alpha-linked acidic dipeptidase 2 chr11 GO:0016787 Not Cancer Driver No 165 0.223 22 4 0.182 0
NAALADL1 NAALADL1 Q9UQQ1 Aminopeptidase NAALADL1 chr11 GO:0016787 Not Cancer Driver No 105 0.142 135 17 0.126 0
NAALADL2 NAALADL2 Q58DX5 Inactive N-acetylated-alpha-linked acidic dipeptidase-like protein 2 chr3 GO:0016787 Not Cancer Driver No 162 0.204 207 46 0.222 0
NADSYN1 NADSYN1 Q6IA69 Glutamine-dependent NAD(+) synthetase chr11 GO:0016787 Not Cancer Driver No 82 0.116 27 8 0.296 3
NAGA NAGA P17050 Alpha-N-acetylgalactosaminidase chr22 GO:0016787 Not Cancer Driver No 47 0.114 2 0 0.0 4
NAGLU NAGLU P54802 Alpha-N-acetylglucosaminidase chr17 GO:0016787 Not Cancer Driver No 70 0.094 18 1 0.056 68
NAGPA NAGPA Q9UK23 N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase chr16 GO:0016787 Not Cancer Driver No 47 0.091 131 11 0.084 0
NANP NANP Q8TBE9 N-acylneuraminate-9-phosphatase chr20 GO:0016787 Not Cancer Driver No 18 0.073 4 0 0.0 0
NAPEPLD NAPEPLD Q6IQ20 N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D chr7 GO:0016787 Not Cancer Driver No 55 0.14 76 7 0.092 0
NAPSA NAPSA O96009 Napsin-A chr19 GO:0016787 Not Cancer Driver No 58 0.138 14 1 0.071 0
NCLN NCLN Q969V3 Nicalin chr19 GO:0016787 Not Cancer Driver No 42 0.075 38 4 0.105 0
NCSTN NCSTN Q92542 Nicastrin chr1 GO:0016787 Not Cancer Driver No 94 0.133 72 11 0.153 1
NDEL1 NDEL1 Q9GZM8 Nuclear distribution protein nudE-like 1 chr17 GO:0016787 Not Cancer Driver No 32 0.093 202 16 0.079 0
NDST1 NDST1 P52848 Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 chr5 GO:0016787 Not Cancer Driver No 117 0.133 22 1 0.045 4
NDST2 NDST2 P52849 Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 chr10 GO:0016787 Not Cancer Driver No 95 0.108 60 7 0.117 0
NDST3 NDST3 O95803 Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3 chr4 GO:0016787 Not Cancer Driver No 186 0.213 9 1 0.111 0
NEU1 NEU1 Q99519 Sialidase-1 chr6 GO:0016787 Not Cancer Driver No 52 0.125 65 6 0.092 23
NEU2 NEU2 Q9Y3R4 Sialidase-2 chr2 GO:0016787 Not Cancer Driver No 88 0.232 144 32 0.222 0
NEU4_ENST00000407683 NEU4 Q8WWR8 Sialidase-4 chr2 GO:0016787 Not Cancer Driver No 82 0.169 199 37 0.186 0
NGLY1 NGLY1 Q96IV0 Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase chr3 GO:0016787 Not Cancer Driver No 79 0.121 98 13 0.133 0
NIT1 NIT1 Q86X76 Deaminated glutathione amidase chr1 GO:0016787 Not Cancer Driver No 41 0.125 18 3 0.167 0
NIT2 NIT2 Q9NQR4 Omega-amidase NIT2 chr3 GO:0016787 Not Cancer Driver No 47 0.17 0 0 0.0 0
NOCT NOCT Q9UK39 Nocturnin chr4 GO:0016787 Not Cancer Driver No 33 0.077 89 3 0.034 0
NOTUM NOTUM Q6P988 Palmitoleoyl-protein carboxylesterase NOTUM chr17 GO:0016787 Not Cancer Driver No 50 0.101 73 6 0.082 0
NPEPL1 NPEPL1 Q8NDH3 Probable aminopeptidase NPEPL1 chr20 GO:0016787 Not Cancer Driver No 67 0.128 26 3 0.115 0
NPEPPS NPEPPS P55786 Puromycin-sensitive aminopeptidase chr17 GO:0016787 Compendium Yes 102 0.111 45 5 0.111 0
NRAS NRAS P01111 GTPase NRas chr1 GO:0016787 Census, Compendium Yes 284 1.503 10 0 0.0 14
NRIP2 NRIP2 Q9BQI9 Nuclear receptor-interacting protein 2 chr12 GO:0016787 Not Cancer Driver No 32 0.114 158 15 0.095 0
NRIP3 NRIP3 Q9NQ35 Nuclear receptor-interacting protein 3 chr11 GO:0016787 Not Cancer Driver No 34 0.141 111 16 0.144 0
NT5C NT5C Q8TCD5 5'(3')-deoxyribonucleotidase, cytosolic type chr17 GO:0016787 Not Cancer Driver No 19 0.095 4 0 0.0 0
NT5C1A NT5C1A Q9BXI3 Cytosolic 5'-nucleotidase 1A chr1 GO:0016787 Not Cancer Driver No 86 0.234 95 16 0.168 0
NT5C2_ENST00000404739 NT5C2 P49902 Cytosolic purine 5'-nucleotidase chr10 GO:0016787 Census Yes 57 0.102 85 8 0.094 0
NTAN1 NTAN1 Q96AB6 Protein N-terminal asparagine amidohydrolase chr16 GO:0016787 Not Cancer Driver No 27 0.087 87 6 0.069 0
NTHL1 NTHL1 P78549 Endonuclease III-like protein 1 chr16 GO:0016787 Census Yes 38 0.122 147 18 0.122 0
NUDT10_ENST00000356450 NUDT10 Q8NFP7 Diphosphoinositol polyphosphate phosphohydrolase 3-alpha chrX GO:0016787 Not Cancer Driver No 29 0.177 68 8 0.118 0
NUDT11 NUDT11 Q96G61 Diphosphoinositol polyphosphate phosphohydrolase 3-beta chrX GO:0016787 Not Cancer Driver No 30 0.183 65 13 0.2 0
NUDT12 NUDT12 Q9BQG2 NAD-capped RNA hydrolase NUDT12 chr5 GO:0016787 Not Cancer Driver No 65 0.141 11 2 0.182 0
NUDT13 NUDT13 Q86X67 NAD(P)H pyrophosphatase NUDT13, mitochondrial chr10 GO:0016787 Not Cancer Driver No 40 0.114 19 0 0.0 0
NUDT14 NUDT14 O95848 Uridine diphosphate glucose pyrophosphatase NUDT14 chr14 GO:0016787 Not Cancer Driver No 27 0.122 39 8 0.205 0
NUDT15 NUDT15 Q9NV35 Nucleotide triphosphate diphosphatase NUDT15 chr13 GO:0016787 Not Cancer Driver No 24 0.146 37 3 0.081 0
NUDT16L1 NUDT16L1 Q9BRJ7 Tudor-interacting repair regulator protein chr16 GO:0016787 Not Cancer Driver No 16 0.076 6 0 0.0 0
NUDT16_ENST00000521288 NUDT16 Q96DE0 U8 snoRNA-decapping enzyme chr3 GO:0016787 Not Cancer Driver No 29 0.149 8 1 0.125 0
NUDT17 NUDT17 P0C025 Nucleoside diphosphate-linked moiety X motif 17 chr1 GO:0016787 Not Cancer Driver No 33 0.101 91 15 0.165 0
NUDT18 NUDT18 Q6ZVK8 8-oxo-dGDP phosphatase NUDT18 chr8 GO:0016787 Not Cancer Driver No 22 0.068 39 3 0.077 0
NUDT19 NUDT19 A8MXV4 Acyl-coenzyme A diphosphatase NUDT19 chr19 GO:0016787 Not Cancer Driver No 27 0.072 131 5 0.038 0
NUDT1_ENST00000397046 NUDT1 P36639 Oxidized purine nucleoside triphosphate hydrolase chr7 GO:0016787 Not Cancer Driver No 25 0.16 17 4 0.235 0
NUDT22 NUDT22 Q9BRQ3 Uridine diphosphate glucose pyrophosphatase NUDT22 chr11 GO:0016787 Not Cancer Driver No 23 0.076 73 6 0.082 0
NUDT2_ENST00000346365 NUDT2 P50583 Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] chr9 GO:0016787 Not Cancer Driver No 16 0.109 24 1 0.042 0
NUDT3 NUDT3 O95989 Diphosphoinositol polyphosphate phosphohydrolase 1 chr6 GO:0016787 Not Cancer Driver No 22 0.128 38 5 0.132 0
NUDT4B NUDT4B A0A024RBG1 Diphosphoinositol polyphosphate phosphohydrolase NUDT4B chr1 GO:0016787 Not Cancer Driver No 2 0.011 53 0 0.0 0
NUDT4_ENST00000415493 NUDT4 Q9NZJ9 Diphosphoinositol polyphosphate phosphohydrolase 2 chr12 GO:0016787 Not Cancer Driver No 20 0.111 53 9 0.17 0
NUDT5_ENST00000537776 NUDT5 Q9UKK9 ADP-sugar pyrophosphatase chr10 GO:0016787 Not Cancer Driver No 27 0.123 90 11 0.122 0
NUDT6 NUDT6 P53370 Nucleoside diphosphate-linked moiety X motif 6 chr4 GO:0016787 Not Cancer Driver No 40 0.127 14 0 0.0 0
NUDT7 NUDT7 P0C024 Peroxisomal coenzyme A diphosphatase NUDT7 chr16 GO:0016787 Not Cancer Driver No 45 0.189 42 4 0.095 0
NUDT8 NUDT8 Q8WV74 Mitochondrial coenzyme A diphosphatase NUDT8 chr11 GO:0016787 Not Cancer Driver No 22 0.093 69 10 0.145 0
NUDT9 NUDT9 Q9BW91 ADP-ribose pyrophosphatase, mitochondrial chr4 GO:0016787 Not Cancer Driver No 27 0.077 177 16 0.09 0
OARD1 OARD1 Q9Y530 ADP-ribose glycohydrolase OARD1 chr6 GO:0016787 Not Cancer Driver No 14 0.092 13 0 0.0 0
OCRL OCRL Q01968 Inositol polyphosphate 5-phosphatase OCRL chrX GO:0016787 Not Cancer Driver No 151 0.168 126 24 0.19 41
OGA OGA O60502 Protein O-GlcNAcase chr10 GO:0016787 Not Cancer Driver No 89 0.097 241 15 0.062 0
OGG1_ENST00000344629 OGG1 O15527 N-glycosylase/DNA lyase chr3 GO:0016787 Not Cancer Driver No 37 0.107 71 12 0.169 0
OLAH_ENST00000378228 OLAH Q9NV23 S-acyl fatty acid synthase thioesterase, medium chain chr10 GO:0016787 Not Cancer Driver No 53 0.2 44 13 0.295 0
OPLAH OPLAH O14841 5-oxoprolinase chr8 GO:0016787 Not Cancer Driver No 141 0.109 323 37 0.115 0
OTOG OTOG Q6ZRI0 Otogelin chr11 GO:0016787 Not Cancer Driver No 62 0.021 728 27 0.037 1
OTOGL OTOGL Q3ZCN5 Otogelin-like protein chr12 GO:0016787 Not Cancer Driver No 473 0.201 0 0 0.0 0
OTUB1_ENST00000428192 OTUB1 Q96FW1 Ubiquitin thioesterase OTUB1 chr11 GO:0016787 Not Cancer Driver No 31 0.114 33 2 0.061 0
OTUD4_ENST00000447906 OTUD4 Q01804 OTU domain-containing protein 4 chr4 GO:0016787 Not Cancer Driver No 148 0.133 788 120 0.152 0
OTUD5 OTUD5 Q96G74 OTU domain-containing protein 5 chrX GO:0016787 Not Cancer Driver No 55 0.096 430 39 0.091 4
OTUD7B OTUD7B Q6GQQ9 OTU domain-containing protein 7B chr1 GO:0016787 Not Cancer Driver No 124 0.147 537 87 0.162 0
OVCA2 OVCA2 Q8WZ82 Esterase OVCA2 chr17 GO:0016787 Not Cancer Driver No 12 0.053 34 0 0.0 0
PADI1 PADI1 Q9ULC6 Protein-arginine deiminase type-1 chr1 GO:0016787 Not Cancer Driver No 114 0.172 43 7 0.163 0
PADI2 PADI2 Q9Y2J8 Protein-arginine deiminase type-2 chr1 GO:0016787 Not Cancer Driver No 121 0.182 60 18 0.3 0
PADI3 PADI3 Q9ULW8 Protein-arginine deiminase type-3 chr1 GO:0016787 Not Cancer Driver No 139 0.209 25 8 0.32 3
PADI4 PADI4 Q9UM07 Protein-arginine deiminase type-4 chr1 GO:0016787 Not Cancer Driver No 115 0.173 114 23 0.202 0
PADI6 PADI6 Q6TGC4 Protein-arginine deiminase type-6 chr1 GO:0016787 Not Cancer Driver No 101 0.146 27 5 0.185 2
PAFAH1B2 PAFAH1B2 P68402 Platelet-activating factor acetylhydrolase IB subunit alpha2 chr11 GO:0016787 Census Yes 25 0.109 43 1 0.023 0
PAFAH1B3_ENST00000262890 PAFAH1B3 Q15102 Platelet-activating factor acetylhydrolase IB subunit alpha1 chr19 GO:0016787 Not Cancer Driver No 15 0.065 76 3 0.039 0
PAFAH2_ENST00000374284 PAFAH2 Q99487 Platelet-activating factor acetylhydrolase 2, cytoplasmic chr1 GO:0016787 Not Cancer Driver No 62 0.158 41 7 0.171 0
PAN2_ENST00000548043 PAN2 Q504Q3 PAN2-PAN3 deadenylation complex catalytic subunit PAN2 chr12 GO:0016787 Not Cancer Driver No 139 0.116 78 10 0.128 0
PAN3 PAN3 Q58A45 PAN2-PAN3 deadenylation complex subunit PAN3 chr13 GO:0016787 Not Cancer Driver No 104 0.117 323 35 0.108 0
PANK4 PANK4 Q9NVE7 4'-phosphopantetheine phosphatase chr1 GO:0016787 Not Cancer Driver No 92 0.119 71 15 0.211 0
PARG_ENST00000616448 PARG Q86W56 Poly(ADP-ribose) glycohydrolase chr10 GO:0016787 Not Cancer Driver No 60 0.061 519 1 0.002 0
PARN PARN O95453 Poly(A)-specific ribonuclease PARN chr16 GO:0016787 Not Cancer Driver No 71 0.111 197 22 0.112 2
PCNA PCNA P12004 Proliferating cell nuclear antigen chr20 GO:0016787 Not Cancer Driver No 30 0.115 22 3 0.136 1
PDE10A_ENST00000366882 PDE10A Q9Y233 cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A chr6 GO:0016787 Not Cancer Driver No 198 0.254 79 21 0.266 4
PDE12 PDE12 Q6L8Q7 2',5'-phosphodiesterase 12 chr3 GO:0016787 Not Cancer Driver No 59 0.097 129 8 0.062 0
PDE1A_ENST00000410103 PDE1A P54750 Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A chr2 GO:0016787 Not Cancer Driver No 157 0.293 61 7 0.115 0
PDE1B PDE1B Q01064 Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B chr12 GO:0016787 Not Cancer Driver No 114 0.213 132 30 0.227 0
PDE1C_ENST00000321453 PDE1C Q14123 Dual specificity Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C chr7 GO:0016787 Not Cancer Driver No 253 0.357 281 97 0.345 1
PDE2A PDE2A O00408 cGMP-dependent 3',5'-cyclic phosphodiesterase chr11 GO:0016787 Not Cancer Driver No 137 0.146 99 7 0.071 0
PDE3A PDE3A Q14432 cGMP-inhibited 3',5'-cyclic phosphodiesterase A chr12 GO:0016787 Not Cancer Driver No 274 0.24 527 114 0.216 6
PDE3B PDE3B Q13370 cGMP-inhibited 3',5'-cyclic phosphodiesterase B chr11 GO:0016787 Not Cancer Driver No 135 0.121 393 37 0.094 0
PDF PDF Q9HBH1 Peptide deformylase, mitochondrial chr16 GO:0016787 Not Cancer Driver No 7 0.029 8 0 0.0 0
PDP1_ENST00000297598 PDP1 Q9P0J1 [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial chr8 GO:0016787 Not Cancer Driver No 64 0.119 96 9 0.094 0
PDP2 PDP2 Q9P2J9 [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial chr16 GO:0016787 Not Cancer Driver No 52 0.098 51 11 0.216 0
PDXP PDXP Q96GD0 Chronophin chr22 GO:0016787 Not Cancer Driver No 14 0.047 38 4 0.105 0
PEPD PEPD P12955 Xaa-Pro dipeptidase chr19 GO:0016787 Not Cancer Driver No 53 0.108 17 2 0.118 4
PFKFB1 PFKFB1 P16118 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 chrX GO:0016787 Not Cancer Driver No 81 0.172 48 11 0.229 0
PFKFB2 PFKFB2 O60825 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 chr1 GO:0016787 Not Cancer Driver No 68 0.135 97 18 0.186 0
PFKFB3_ENST00000379775 PFKFB3 Q16875 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 chr10 GO:0016787 Not Cancer Driver No 65 0.125 97 19 0.196 0
PFKFB4 PFKFB4 Q16877 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 chr3 GO:0016787 Not Cancer Driver No 71 0.151 44 3 0.068 0
PGA3 PGA3 P0DJD8 Pepsin A-3 chr11 GO:0016787 Not Cancer Driver No 19 0.049 24 1 0.042 0
PGA4 PGA4 P0DJD7 Pepsin A-4 chr11 GO:0016787 Not Cancer Driver No 0 0.0 24 0 0.0 0
PGA5 PGA5 P0DJD9 Pepsin A-5 chr11 GO:0016787 Not Cancer Driver No 25 0.064 24 2 0.083 0
PGAM1 PGAM1 P18669 Phosphoglycerate mutase 1 chr10 GO:0016787 Not Cancer Driver No 20 0.079 70 5 0.071 0
PGAM2 PGAM2 P15259 Phosphoglycerate mutase 2 chr7 GO:0016787 Not Cancer Driver No 46 0.182 81 14 0.173 3
PGAM4 PGAM4 Q8N0Y7 Probable phosphoglycerate mutase 4 chrX GO:0016787 Not Cancer Driver No 42 0.165 62 9 0.145 0
PGAP1 PGAP1 Q75T13 GPI inositol-deacylase chr2 GO:0016787 Not Cancer Driver No 127 0.138 21 7 0.333 0
PGC PGC P20142 Gastricsin chr6 GO:0016787 Not Cancer Driver No 60 0.155 20 1 0.05 0
PGGHG PGGHG Q32M88 Protein-glucosylgalactosylhydroxylysine glucosidase chr11 GO:0016787 Not Cancer Driver No 77 0.104 168 16 0.095 0
PGLS PGLS O95336 6-phosphogluconolactonase chr19 GO:0016787 Not Cancer Driver No 20 0.078 36 4 0.111 0
PGLYRP1 PGLYRP1 O75594 Peptidoglycan recognition protein 1 chr19 GO:0016787 Not Cancer Driver No 34 0.173 4 0 0.0 0
PGLYRP2 PGLYRP2 Q96PD5 N-acetylmuramoyl-L-alanine amidase chr19 GO:0016787 Not Cancer Driver No 111 0.193 160 28 0.175 0
PGLYRP3 PGLYRP3 Q96LB9 Peptidoglycan recognition protein 3 chr1 GO:0016787 Not Cancer Driver No 81 0.238 0 0 0.0 0
PGLYRP4 PGLYRP4 Q96LB8 Peptidoglycan recognition protein 4 chr1 GO:0016787 Not Cancer Driver No 81 0.217 4 1 0.25 0
PGP PGP A6NDG6 Glycerol-3-phosphate phosphatase chr16 GO:0016787 Not Cancer Driver No 10 0.031 21 0 0.0 0
PGPEP1 PGPEP1 Q9NXJ5 Pyroglutamyl-peptidase 1 chr19 GO:0016787 Not Cancer Driver No 22 0.105 0 0 0.0 0
PHOSPHO1_ENST00000310544 PHOSPHO1 Q8TCT1 Phosphoethanolamine/phosphocholine phosphatase chr17 GO:0016787 Not Cancer Driver No 14 0.052 18 0 0.0 0
PHOSPHO2_ENST00000616481 PHOSPHO2 Q8TCD6 Pyridoxal phosphate phosphatase PHOSPHO2 chr2 GO:0016787 Not Cancer Driver No 38 0.158 0 0 0.0 0
PHPT1 PHPT1 Q9NRX4 14 kDa phosphohistidine phosphatase chr9 GO:0016787 Not Cancer Driver No 13 0.104 6 0 0.0 0
PIGK PIGK Q92643 GPI-anchor transamidase chr1 GO:0016787 Not Cancer Driver No 54 0.137 37 9 0.243 5
PIGL PIGL Q9Y2B2 N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase chr17 GO:0016787 Not Cancer Driver No 27 0.107 4 0 0.0 1
PIK3AP1 PIK3AP1 Q6ZUJ8 Phosphoinositide 3-kinase adapter protein 1 chr10 GO:0016787 Not Cancer Driver No 141 0.175 406 81 0.2 0
PIKFYVE PIKFYVE Q9Y2I7 1-phosphatidylinositol 3-phosphate 5-kinase chr2 GO:0016787 Not Cancer Driver No 278 0.133 848 101 0.119 1
PIP PIP P12273 Prolactin-inducible protein chr7 GO:0016787 Not Cancer Driver No 42 0.288 0 0 0.0 0
PIP4P1_ENST00000250489 PIP4P1 Q86T03 Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase chr14 GO:0016787 Not Cancer Driver No 36 0.13 78 4 0.051 0
PIP4P2 PIP4P2 Q8N4L2 Type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase chr8 GO:0016787 Not Cancer Driver No 41 0.16 46 4 0.087 0
PLA1A PLA1A Q53H76 Phospholipase A1 member A chr3 GO:0016787 Not Cancer Driver No 94 0.206 10 0 0.0 0
PLA2G10 PLA2G10 O15496 Group 10 secretory phospholipase A2 chr16 GO:0016787 Not Cancer Driver No 5 0.03 0 0 0.0 0
PLA2G12A PLA2G12A Q9BZM1 Group XIIA secretory phospholipase A2 chr4 GO:0016787 Not Cancer Driver No 18 0.095 0 0 0.0 0
PLA2G15 PLA2G15 Q8NCC3 Phospholipase A2 group XV chr16 GO:0016787 Not Cancer Driver No 61 0.148 11 3 0.273 0
PLA2G16 PLAAT3 P53816 Phospholipase A and acyltransferase 3 chr11 GO:0016787 Not Cancer Driver No 16 0.099 13 1 0.077 0
PLA2G1B PLA2G1B P04054 Phospholipase A2 chr12 GO:0016787 Not Cancer Driver No 17 0.115 0 0 0.0 0
PLA2G2A_ENST00000375111 PLA2G2A P14555 Phospholipase A2, membrane associated chr1 GO:0016787 Not Cancer Driver No 25 0.174 0 0 0.0 0
PLA2G2C_ENST00000429261 PLA2G2C Q5R387 Putative inactive group IIC secretory phospholipase A2 chr1 GO:0016787 Not Cancer Driver No 18 0.121 10 0 0.0 0
PLA2G2D PLA2G2D Q9UNK4 Group IID secretory phospholipase A2 chr1 GO:0016787 Not Cancer Driver No 27 0.186 0 0 0.0 0
PLA2G2E PLA2G2E Q9NZK7 Group IIE secretory phospholipase A2 chr1 GO:0016787 Not Cancer Driver No 33 0.232 0 0 0.0 0
PLA2G3 PLA2G3 Q9NZ20 Group 3 secretory phospholipase A2 chr22 GO:0016787 Not Cancer Driver No 115 0.226 175 39 0.223 0
PLA2G4A PLA2G4A P47712 Cytosolic phospholipase A2 chr1 GO:0016787 Not Cancer Driver No 149 0.199 129 28 0.217 1
PLA2G4B_ENST00000458483 PLA2G4B P0C869 Cytosolic phospholipase A2 beta chr15 GO:0016787 Not Cancer Driver No 88 0.113 144 18 0.125 0
PLA2G4C_ENST00000599921 PLA2G4C Q9UP65 Cytosolic phospholipase A2 gamma chr19 GO:0016787 Not Cancer Driver No 107 0.198 62 9 0.145 0
PLA2G4D PLA2G4D Q86XP0 Cytosolic phospholipase A2 delta chr15 GO:0016787 Not Cancer Driver No 115 0.141 172 17 0.099 0
PLA2G4E PLA2G4E Q3MJ16 Cytosolic phospholipase A2 epsilon chr15 GO:0016787 Not Cancer Driver No 71 0.082 123 6 0.049 0
PLA2G4F PLA2G4F Q68DD2 Cytosolic phospholipase A2 zeta chr15 GO:0016787 Not Cancer Driver No 121 0.143 106 6 0.057 0
PLA2G5 PLA2G5 P39877 Phospholipase A2 group V chr1 GO:0016787 Not Cancer Driver No 24 0.174 0 0 0.0 2
PLA2G6 PLA2G6 O60733 85/88 kDa calcium-independent phospholipase A2 chr22 GO:0016787 Not Cancer Driver No 108 0.134 148 23 0.155 11
PLA2G7 PLA2G7 Q13093 Platelet-activating factor acetylhydrolase chr6 GO:0016787 Not Cancer Driver No 70 0.159 27 7 0.259 2
PLB1 PLB1 Q6P1J6 Phospholipase B1, membrane-associated chr2 GO:0016787 Not Cancer Driver No 223 0.153 399 57 0.143 0
PLCB1 PLCB1 Q9NQ66 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 chr20 GO:0016787 Not Cancer Driver No 313 0.257 481 104 0.216 0
PLCB2 PLCB2 Q00722 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 chr15 GO:0016787 Not Cancer Driver No 161 0.136 495 51 0.103 0
PLCB3 PLCB3 Q01970 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 chr11 GO:0016787 Not Cancer Driver No 144 0.117 595 68 0.114 1
PLCB4_ENST00000278655 PLCB4 Q15147 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 chr20 GO:0016787 Compendium Yes 338 0.288 401 120 0.299 5
PLCD1_ENST00000334661 PLCD1 P51178 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 chr3 GO:0016787 Not Cancer Driver No 94 0.124 111 13 0.117 2
PLCD3 PLCD3 Q8N3E9 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 chr17 GO:0016787 Not Cancer Driver No 61 0.077 229 22 0.096 0
PLCD4_ENST00000417849 PLCD4 Q9BRC7 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 chr2 GO:0016787 Not Cancer Driver No 78 0.102 90 5 0.056 0
PLCE1 PLCE1 Q9P212 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 chr10 GO:0016787 Not Cancer Driver No 367 0.159 780 107 0.137 1
PLCG1_ENST00000373271 PLCG1 P19174 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 chr20 GO:0016787 Census, Compendium Yes 158 0.122 186 21 0.113 0
PLCG2 PLCG2 P16885 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 chr16 GO:0016787 Not Cancer Driver No 248 0.196 142 30 0.211 1
PLCH1 PLCH1 Q4KWH8 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 chr3 GO:0016787 Not Cancer Driver No 383 0.226 772 195 0.253 0
PLCH2 PLCH2 O75038 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2 chr1 GO:0016787 Not Cancer Driver No 145 0.102 786 71 0.09 0
PLCL1 PLCL1 Q15111 Inactive phospholipase C-like protein 1 chr2 GO:0016787 Not Cancer Driver No 258 0.236 205 33 0.161 0
PLCL2 PLCL2 Q9UPR0 Inactive phospholipase C-like protein 2 chr3 GO:0016787 Not Cancer Driver No 185 0.164 274 31 0.113 0
PLCZ1 PLCZ1 Q86YW0 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 chr12 GO:0016787 Not Cancer Driver No 151 0.248 37 20 0.541 1
PLD1 PLD1 Q13393 Phospholipase D1 chr3 GO:0016787 Not Cancer Driver No 181 0.169 133 32 0.241 1
PLD2 PLD2 O14939 Phospholipase D2 chr17 GO:0016787 Not Cancer Driver No 107 0.115 97 8 0.082 0
PLD3_ENST00000409735 PLD3 Q8IV08 5'-3' exonuclease PLD3 chr19 GO:0016787 Not Cancer Driver No 70 0.143 62 7 0.113 0
PLD4_ENST00000392593 PLD4 Q96BZ4 5'-3' exonuclease PLD4 chr14 GO:0016787 Not Cancer Driver No 46 0.091 76 10 0.132 0
PLD6 PLD6 Q8N2A8 Mitochondrial cardiolipin hydrolase chr17 GO:0016787 Not Cancer Driver No 27 0.107 24 6 0.25 0
PLPP1_ENST00000307259 PLPP1 O14494 Phospholipid phosphatase 1 chr5 GO:0016787 Not Cancer Driver No 28 0.099 27 1 0.037 0
PLPP2_ENST00000434325 PLPP2 O43688 Phospholipid phosphatase 2 chr19 GO:0016787 Not Cancer Driver No 47 0.163 0 0 0.0 0
PLPP3 PLPP3 O14495 Phospholipid phosphatase 3 chr1 GO:0016787 Not Cancer Driver No 48 0.154 10 1 0.1 0
PLPP4 PLPP4 Q5VZY2 Phospholipid phosphatase 4 chr10 GO:0016787 Not Cancer Driver No 59 0.218 14 1 0.071 0
PLPP5 PLPP5 Q8NEB5 Phospholipid phosphatase 5 chr8 GO:0016787 Not Cancer Driver No 22 0.083 0 0 0.0 0
PLPP6 PLPP6 Q8IY26 Polyisoprenoid diphosphate/phosphate phosphohydrolase PLPP6 chr9 GO:0016787 Not Cancer Driver No 16 0.054 80 0 0.0 0
PLPP7 PLPP7 Q8NBV4 Inactive phospholipid phosphatase 7 chr9 GO:0016787 Not Cancer Driver No 45 0.166 72 9 0.125 0
PLPPR1_ENST00000395056 PLPPR1 Q8TBJ4 Phospholipid phosphatase-related protein type 1 chr9 GO:0016787 Not Cancer Driver No 78 0.24 34 16 0.471 0
PLPPR2_ENST00000251473 PLPPR2 Q96GM1 Phospholipid phosphatase-related protein type 2 chr19 GO:0016787 Not Cancer Driver No 55 0.16 55 7 0.127 0
PLPPR3_ENST00000520876 PLPPR3 Q6T4P5 Phospholipid phosphatase-related protein type 3 chr19 GO:0016787 Not Cancer Driver No 50 0.07 431 8 0.019 0
PLPPR4 PLPPR4 Q7Z2D5 Phospholipid phosphatase-related protein type 4 chr1 GO:0016787 Not Cancer Driver No 177 0.232 457 118 0.258 0
PLPPR5 PLPPR5 Q32ZL2 Phospholipid phosphatase-related protein type 5 chr1 GO:0016787 Not Cancer Driver No 74 0.231 0 0 0.0 0
PM20D1 PM20D1 Q6GTS8 N-fatty-acyl-amino acid synthase/hydrolase PM20D1 chr1 GO:0016787 Not Cancer Driver No 79 0.157 42 10 0.238 0
PM20D2 PM20D2 Q8IYS1 Xaa-Arg dipeptidase chr6 GO:0016787 Not Cancer Driver No 39 0.089 79 7 0.089 0
PNKD PNKD Q8N490 Probable hydrolase PNKD chr2 GO:0016787 Not Cancer Driver No 52 0.135 160 25 0.156 2
PNKP PNKP Q96T60 Bifunctional polynucleotide phosphatase/kinase chr19 GO:0016787 Not Cancer Driver No 53 0.102 177 23 0.13 4
PNLDC1_ENST00000610273 PNLDC1 Q8NA58 Poly(A)-specific ribonuclease PNLDC1 chr6 GO:0016787 Not Cancer Driver No 105 0.202 6 0 0.0 1
PNLIP PNLIP P16233 Pancreatic triacylglycerol lipase chr10 GO:0016787 Not Cancer Driver No 124 0.267 32 11 0.344 1
PNLIPRP2 PNLIPRP2 P54317 Pancreatic lipase-related protein 2 chr10 GO:0016787 Not Cancer Driver No 75 0.16 28 2 0.071 0
PNPLA2 PNPLA2 Q96AD5 Patatin-like phospholipase domain-containing protein 2 chr11 GO:0016787 Not Cancer Driver No 35 0.069 101 4 0.04 1
PNPLA3 PNPLA3 Q9NST1 1-acylglycerol-3-phosphate O-acyltransferase PNPLA3 chr22 GO:0016787 Not Cancer Driver No 54 0.112 33 7 0.212 0
PNPLA4_ENST00000444736 PNPLA4 P41247 Patatin-like phospholipase domain-containing protein 4 chrX GO:0016787 Not Cancer Driver No 41 0.162 3 0 0.0 0
PNPLA6 PNPLA6 Q8IY17 Patatin-like phospholipase domain-containing protein 6 chr19 GO:0016787 Not Cancer Driver No 171 0.124 367 49 0.134 18
PNPLA7_ENST00000277531 PNPLA7 Q6ZV29 Patatin-like phospholipase domain-containing protein 7 chr9 GO:0016787 Not Cancer Driver No 180 0.137 283 35 0.124 0
PNPLA8 PNPLA8 Q9NP80 Calcium-independent phospholipase A2-gamma chr7 GO:0016787 Not Cancer Driver No 94 0.12 140 18 0.129 0
POLE POLE Q07864 DNA polymerase epsilon catalytic subunit A chr12 GO:0016787 Census, Compendium Yes 409 0.179 239 44 0.184 3
PON1 PON1 P27169 Serum paraoxonase/arylesterase 1 chr7 GO:0016787 Not Cancer Driver No 80 0.225 10 9 0.9 0
PON2 PON2 Q15165 Serum paraoxonase/arylesterase 2 chr7 GO:0016787 Not Cancer Driver No 46 0.13 13 3 0.231 0
PON3 PON3 Q15166 Serum paraoxonase/lactonase 3 chr7 GO:0016787 Not Cancer Driver No 69 0.195 32 6 0.188 0
POP1_ENST00000349693 POP1 Q99575 Ribonucleases P/MRP protein subunit POP1 chr8 GO:0016787 Not Cancer Driver No 161 0.157 495 75 0.152 3
POP4 POP4 O95707 Ribonuclease P protein subunit p29 chr19 GO:0016787 Not Cancer Driver No 25 0.114 53 9 0.17 0
POP5 POP5 Q969H6 Ribonuclease P/MRP protein subunit POP5 chr12 GO:0016787 Not Cancer Driver No 17 0.104 9 2 0.222 0
POP7 POP7 O75817 Ribonuclease P protein subunit p20 chr7 GO:0016787 Not Cancer Driver No 20 0.143 59 13 0.22 0
POR POR P16435 NADPH--cytochrome P450 reductase chr7 GO:0016787 Not Cancer Driver No 62 0.092 93 4 0.043 9
PPA1 PPA1 Q15181 Inorganic pyrophosphatase chr10 GO:0016787 Not Cancer Driver No 31 0.107 24 0 0.0 0
PPA2 PPA2 Q9H2U2 Inorganic pyrophosphatase 2, mitochondrial chr4 GO:0016787 Not Cancer Driver No 49 0.147 71 9 0.127 9
PPM1A_ENST00000395076 PPM1A P35813 Protein phosphatase 1A chr14 GO:0016787 Not Cancer Driver No 60 0.157 134 24 0.179 0
PPM1F PPM1F P49593 Protein phosphatase 1F chr22 GO:0016787 Not Cancer Driver No 53 0.117 242 24 0.099 0
PPME1_ENST00000328257 PPME1 Q9Y570 Protein phosphatase methylesterase 1 chr11 GO:0016787 Not Cancer Driver No 35 0.091 146 9 0.062 0
PPP1CB_ENST00000358506 PPP1CB P62140 Serine/threonine-protein phosphatase PP1-beta catalytic subunit chr2 GO:0016787 Not Cancer Driver No 47 0.144 25 5 0.2 5
PPP1R3B PPP1R3B Q86XI6 Protein phosphatase 1 regulatory subunit 3B chr8 GO:0016787 Not Cancer Driver No 36 0.126 19 2 0.105 0
PPP1R3E PPP1R3E Q9H7J1 Protein phosphatase 1 regulatory subunit 3E chr14 GO:0016787 Not Cancer Driver No 1 0.004 182 0 0.0 0
PPP1R8 PPP1R8 Q12972 Nuclear inhibitor of protein phosphatase 1 chr1 GO:0016787 Not Cancer Driver No 24 0.068 251 19 0.076 0
PPP3CA PPP3CA Q08209 Protein phosphatase 3 catalytic subunit alpha chr4 GO:0016787 Compendium Yes 85 0.163 140 27 0.193 7
PPP3CB_ENST00000360663 PPP3CB P16298 Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform chr10 GO:0016787 Not Cancer Driver No 67 0.128 139 18 0.129 0
PPP3CC_ENST00000240139 PPP3CC P48454 Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform chr8 GO:0016787 Not Cancer Driver No 47 0.092 91 7 0.077 0
PPP3R1 PPP3R1 P63098 Calcineurin subunit B type 1 chr2 GO:0016787 Not Cancer Driver No 19 0.112 1 0 0.0 0
PPT1 PPT1 P50897 Palmitoyl-protein thioesterase 1 chr1 GO:0016787 Not Cancer Driver No 37 0.121 0 0 0.0 23
PPT2_ENST00000395523 PPT2 Q9UMR5 Lysosomal thioesterase PPT2 chr6 GO:0016787 Compendium Yes 45 0.149 0 0 0.0 0
PRCP_ENST00000313010 PRCP P42785 Lysosomal Pro-X carboxypeptidase chr11 GO:0016787 Not Cancer Driver No 58 0.117 0 0 0.0 0
PRDX6 PRDX6 P30041 Peroxiredoxin-6 chr1 GO:0016787 Not Cancer Driver No 46 0.205 13 4 0.308 0
PREP PREP P48147 Prolyl endopeptidase chr6 GO:0016787 Not Cancer Driver No 87 0.123 23 1 0.043 0
PRPF8 PRPF8 Q6P2Q9 Pre-mRNA-processing-splicing factor 8 chr17 GO:0016787 Not Cancer Driver No 255 0.109 225 26 0.116 8
PRSS16 PRSS16 Q9NQE7 Thymus-specific serine protease chr6 GO:0016787 Not Cancer Driver No 85 0.165 26 5 0.192 0
PRSS50 PRSS50 Q9UI38 Probable threonine protease PRSS50 chr3 GO:0016787 Not Cancer Driver No 104 0.27 63 26 0.413 0
PRUNE1 PRUNE1 Q86TP1 Exopolyphosphatase PRUNE1 chr1 GO:0016787 Not Cancer Driver No 43 0.095 93 14 0.151 4
PSEN1 PSEN1 P49768 Presenilin-1 chr14 GO:0016787 Not Cancer Driver No 61 0.131 134 21 0.157 96
PSEN2 PSEN2 P49810 Presenilin-2 chr1 GO:0016787 Not Cancer Driver No 68 0.152 89 16 0.18 7
PSMA4_ENST00000559082 PSMA4 P25789 Proteasome subunit alpha type-4 chr15 GO:0016787 Not Cancer Driver No 29 0.111 28 9 0.321 0
PSMB1 PSMB1 P20618 Proteasome subunit beta type-1 chr6 GO:0016787 Not Cancer Driver No 25 0.104 14 2 0.143 0
PSMB10 PSMB10 P40306 Proteasome subunit beta type-10 chr16 GO:0016787 Not Cancer Driver No 22 0.081 36 5 0.139 0
PSMB11 PSMB11 A5LHX3 Proteasome subunit beta type-11 chr14 GO:0016787 Not Cancer Driver No 62 0.207 71 11 0.155 0
PSMB2 PSMB2 P49721 Proteasome subunit beta type-2 chr1 GO:0016787 Not Cancer Driver No 24 0.119 0 0 0.0 0
PSMB4 PSMB4 P28070 Proteasome subunit beta type-4 chr1 GO:0016787 Not Cancer Driver No 23 0.087 18 2 0.111 0
PSMB5 PSMB5 P28074 Proteasome subunit beta type-5 chr14 GO:0016787 Not Cancer Driver No 39 0.148 9 0 0.0 0
PSMB6 PSMB6 P28072 Proteasome subunit beta type-6 chr17 GO:0016787 Not Cancer Driver No 19 0.079 22 1 0.045 0
PSMB7 PSMB7 Q99436 Proteasome subunit beta type-7 chr9 GO:0016787 Not Cancer Driver No 25 0.09 26 3 0.115 0
PSMB8 PSMB8 P28062 Proteasome subunit beta type-8 chr6 GO:0016787 Not Cancer Driver No 43 0.156 62 7 0.113 3
PSMB9 PSMB9 P28065 Proteasome subunit beta type-9 chr6 GO:0016787 Not Cancer Driver No 21 0.096 17 1 0.059 1
PSMD14 PSMD14 O00487 26S proteasome non-ATPase regulatory subunit 14 chr2 GO:0016787 Not Cancer Driver No 23 0.074 67 6 0.09 0
PSMD7 PSMD7 P51665 26S proteasome non-ATPase regulatory subunit 7 chr16 GO:0016787 Not Cancer Driver No 39 0.12 70 4 0.057 0
PSPH_ENST00000275605 PSPH P78330 Phosphoserine phosphatase chr7 GO:0016787 Not Cancer Driver No 44 0.196 21 6 0.286 3
PTEN PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 GO:0016787 Census, Compendium Yes 505 1.253 76 4 0.053 41
PTP4A1 PTP4A1 Q93096 Protein tyrosine phosphatase type IVA 1 chr6 GO:0016787 Not Cancer Driver No 21 0.121 2 0 0.0 0
PTP4A2 PTP4A2 Q12974 Protein tyrosine phosphatase type IVA 2 chr1 GO:0016787 Not Cancer Driver No 14 0.084 3 1 0.333 0
PTP4A3_ENST00000521578 PTP4A3 O75365 Protein tyrosine phosphatase type IVA 3 chr8 GO:0016787 Not Cancer Driver No 30 0.173 3 0 0.0 0
PTPDC1_ENST00000375360 PTPDC1 A2A3K4 Protein tyrosine phosphatase domain-containing protein 1 chr9 GO:0016787 Not Cancer Driver No 85 0.113 301 26 0.086 0
PTPMT1 PTPMT1 Q8WUK0 Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 chr11 GO:0016787 Not Cancer Driver No 16 0.08 0 0 0.0 0
PTPN11_ENST00000351677 PTPN11 Q06124 Tyrosine-protein phosphatase non-receptor type 11 chr12 GO:0016787 Census, Compendium Yes 129 0.218 260 38 0.146 60
PTPN12 PTPN12 Q05209 Tyrosine-protein phosphatase non-receptor type 12 chr7 GO:0016787 Not Cancer Driver No 102 0.131 516 60 0.116 0
PTPN18 PTPN18 Q99952 Tyrosine-protein phosphatase non-receptor type 18 chr2 GO:0016787 Not Cancer Driver No 51 0.111 138 8 0.058 0
PTPN22 PTPN22 Q9Y2R2 Tyrosine-protein phosphatase non-receptor type 22 chr1 GO:0016787 Not Cancer Driver No 141 0.175 364 62 0.17 4
PTPN4 PTPN4 P29074 Tyrosine-protein phosphatase non-receptor type 4 chr2 GO:0016787 Not Cancer Driver No 132 0.143 263 32 0.122 0
PTPN6_ENST00000318974 PTPN6 P29350 Tyrosine-protein phosphatase non-receptor type 6 chr12 GO:0016787 Census, Compendium Yes 73 0.123 192 25 0.13 0
PTPN9 PTPN9 P43378 Tyrosine-protein phosphatase non-receptor type 9 chr15 GO:0016787 Not Cancer Driver No 77 0.13 78 5 0.064 0
PTPRA_ENST00000399903 PTPRA P18433 Receptor-type tyrosine-protein phosphatase alpha chr20 GO:0016787 Not Cancer Driver No 98 0.122 210 21 0.1 0
PTPRB_ENST00000261266 PTPRB P23467 Receptor-type tyrosine-protein phosphatase beta chr12 GO:0016787 Census, Compendium Yes 425 0.213 302 65 0.215 0
PTPRC PTPRC P08575 Receptor-type tyrosine-protein phosphatase C chr1 GO:0016787 Census, Compendium Yes 315 0.241 462 107 0.232 0
PTPRD PTPRD P23468 Receptor-type tyrosine-protein phosphatase delta chr9 GO:0016787 Census, Compendium Yes 577 0.302 747 219 0.293 0
PTPRE PTPRE P23469 Receptor-type tyrosine-protein phosphatase epsilon chr10 GO:0016787 Not Cancer Driver No 122 0.174 97 13 0.134 0
PTPRF PTPRF P10586 Receptor-type tyrosine-protein phosphatase F chr1 GO:0016787 Not Cancer Driver No 268 0.141 696 96 0.138 0
PTPRG PTPRG P23470 Receptor-type tyrosine-protein phosphatase gamma chr3 GO:0016787 Not Cancer Driver No 212 0.147 465 61 0.131 0
PTPRH PTPRH Q9HD43 Receptor-type tyrosine-protein phosphatase H chr19 GO:0016787 Not Cancer Driver No 228 0.204 474 74 0.156 0
PTPRK_ENST00000368215 PTPRK Q15262 Receptor-type tyrosine-protein phosphatase kappa chr6 GO:0016787 Census, Compendium Yes 292 0.203 302 57 0.189 0
PTPRM_ENST00000332175 PTPRM P28827 Receptor-type tyrosine-protein phosphatase mu chr18 GO:0016787 Not Cancer Driver No 256 0.176 365 60 0.164 0
PTPRN2 PTPRN2 Q92932 Receptor-type tyrosine-protein phosphatase N2 chr7 GO:0016787 Not Cancer Driver No 274 0.27 580 169 0.291 0
PTPRO PTPRO Q16827 Receptor-type tyrosine-protein phosphatase O chr12 GO:0016787 Not Cancer Driver No 204 0.168 137 34 0.248 0
PTPRR PTPRR Q15256 Receptor-type tyrosine-protein phosphatase R chr12 GO:0016787 Not Cancer Driver No 172 0.262 73 28 0.384 0
PTPRT_ENST00000373187 PTPRT O14522 Receptor-type tyrosine-protein phosphatase T chr20 GO:0016787 Census, Compendium Yes 535 0.371 299 125 0.418 0
PTPRU PTPRU Q92729 Receptor-type tyrosine-protein phosphatase U chr1 GO:0016787 Not Cancer Driver No 248 0.172 325 64 0.197 0
PTPRZ1 PTPRZ1 P23471 Receptor-type tyrosine-protein phosphatase zeta chr7 GO:0016787 Not Cancer Driver No 480 0.207 978 216 0.221 0
PTRH1 PTRH1 Q86Y79 Probable peptidyl-tRNA hydrolase chr9 GO:0016787 Not Cancer Driver No 18 0.084 52 6 0.115 0
PTRH2_ENST00000470557 PTRH2 Q9Y3E5 Peptidyl-tRNA hydrolase 2, mitochondrial chr17 GO:0016787 Not Cancer Driver No 14 0.078 19 2 0.105 1
PTRHD1 PTRHD1 Q6GMV3 Putative peptidyl-tRNA hydrolase PTRHD1 chr2 GO:0016787 Not Cancer Driver No 12 0.086 22 2 0.091 0
PUDP_ENST00000381077 PUDP Q08623 Pseudouridine-5'-phosphatase chrX GO:0016787 Not Cancer Driver No 45 0.197 9 1 0.111 0
QPCT QPCT Q16769 Glutaminyl-peptide cyclotransferase chr2 GO:0016787 Not Cancer Driver No 44 0.122 41 3 0.073 0
QPCTL QPCTL Q9NXS2 Glutaminyl-peptide cyclotransferase-like protein chr19 GO:0016787 Not Cancer Driver No 42 0.11 22 1 0.045 0
RAB10 RAB10 P61026 Ras-related protein Rab-10 chr2 GO:0016787 Not Cancer Driver No 19 0.095 28 2 0.071 0
RAB11A RAB11A P62491 Ras-related protein Rab-11A chr15 GO:0016787 Not Cancer Driver No 31 0.144 43 4 0.093 0
RAB11B RAB11B Q15907 Ras-related protein Rab-11B chr19 GO:0016787 Not Cancer Driver No 26 0.119 39 3 0.077 2
RAB1A RAB1A P62820 Ras-related protein Rab-1A chr2 GO:0016787 Not Cancer Driver No 16 0.078 38 2 0.053 0
RAB1B RAB1B Q9H0U4 Ras-related protein Rab-1B chr11 GO:0016787 Not Cancer Driver No 24 0.119 40 3 0.075 0
RAB27A_ENST00000336787 RAB27A P51159 Ras-related protein Rab-27A chr15 GO:0016787 Not Cancer Driver No 25 0.113 15 4 0.267 3
RAB27B RAB27B O00194 Ras-related protein Rab-27B chr18 GO:0016787 Not Cancer Driver No 42 0.193 43 9 0.209 0
RAB4A RAB4A P20338 Ras-related protein Rab-4A chr1 GO:0016787 Not Cancer Driver No 26 0.119 32 11 0.344 0
RAB4B_ENST00000357052 RAB4B P61018 Ras-related protein Rab-4B chr19 GO:0016787 Not Cancer Driver No 40 0.188 36 10 0.278 0
RAB5A RAB5A P20339 Ras-related protein Rab-5A chr3 GO:0016787 Not Cancer Driver No 32 0.149 65 15 0.231 0
RAB5B RAB5B P61020 Ras-related protein Rab-5B chr12 GO:0016787 Not Cancer Driver No 23 0.107 43 5 0.116 0
RAB5C_ENST00000393860 RAB5C P51148 Ras-related protein Rab-5C chr17 GO:0016787 Not Cancer Driver No 24 0.111 50 4 0.08 0
RAB7A RAB7A P51149 Ras-related protein Rab-7a chr3 GO:0016787 Not Cancer Driver No 27 0.13 11 0 0.0 4
RAC1_ENST00000348035 RAC1 P63000 Ras-related C3 botulinum toxin substrate 1 chr7 GO:0016787 Census, Compendium Yes 66 0.344 2 1 0.5 6
RAC3 RAC3 P60763 Ras-related C3 botulinum toxin substrate 3 chr17 GO:0016787 Not Cancer Driver No 24 0.125 0 0 0.0 4
RAD1 RAD1 O60671 Cell cycle checkpoint protein RAD1 chr5 GO:0016787 Not Cancer Driver No 29 0.103 4 1 0.25 0
RAD50 RAD50 Q92878 DNA repair protein RAD50 chr5 GO:0016787 Not Cancer Driver No 157 0.12 730 84 0.115 0
RAD51C RAD51C O43502 DNA repair protein RAD51 homolog 3 chr17 GO:0016787 Not Cancer Driver No 47 0.125 18 2 0.111 6
RAD54B RAD54B Q9Y620 DNA repair and recombination protein RAD54B chr8 GO:0016787 Not Cancer Driver No 112 0.123 120 16 0.133 0
RAD9A RAD9A Q99638 Cell cycle checkpoint control protein RAD9A chr11 GO:0016787 Not Cancer Driver No 34 0.087 135 7 0.052 0
RAG1 RAG1 P15918 V(D)J recombination-activating protein 1 chr11 GO:0016787 Not Cancer Driver No 204 0.196 208 43 0.207 36
RALA RALA P11233 Ras-related protein Ral-A chr7 GO:0016787 Not Cancer Driver No 34 0.165 34 3 0.088 5
RALB RALB P11234 Ras-related protein Ral-B chr2 GO:0016787 Not Cancer Driver No 36 0.175 35 5 0.143 0
RAP1A_ENST00000356415 RAP1A P62834 Ras-related protein Rap-1A chr1 GO:0016787 Not Cancer Driver No 27 0.147 5 0 0.0 0
RAP1B_ENST00000393436 RAP1B P61224 Ras-related protein Rap-1b chr12 GO:0016787 Not Cancer Driver No 26 0.141 14 3 0.214 0
RAP2A RAP2A P10114 Ras-related protein Rap-2a chr13 GO:0016787 Not Cancer Driver No 15 0.082 9 0 0.0 0
RAP2B RAP2B P61225 Ras-related protein Rap-2b chr3 GO:0016787 Not Cancer Driver No 22 0.12 0 0 0.0 0
RAP2C_ENST00000370874 RAP2C Q9Y3L5 Ras-related protein Rap-2c chrX GO:0016787 Not Cancer Driver No 32 0.175 8 2 0.25 0
RARRES3 PLAAT4 Q9UL19 Phospholipase A and acyltransferase 4 chr11 GO:0016787 Not Cancer Driver No 25 0.152 7 1 0.143 0
RASL10A RASL10A Q92737 Ras-like protein family member 10A chr22 GO:0016787 Not Cancer Driver No 13 0.064 40 0 0.0 0
RASL11A RASL11A Q6T310 Ras-like protein family member 11A chr13 GO:0016787 Not Cancer Driver No 31 0.128 40 6 0.15 0
RASL11B RASL11B Q9BPW5 Ras-like protein family member 11B chr4 GO:0016787 Not Cancer Driver No 24 0.097 33 4 0.121 0
RASL12 RASL12 Q9NYN1 Ras-like protein family member 12 chr15 GO:0016787 Not Cancer Driver No 37 0.139 49 8 0.163 0
RBBP8_ENST00000327155 RBBP8 Q99708 DNA endonuclease RBBP8 chr18 GO:0016787 Not Cancer Driver No 99 0.11 750 76 0.101 1
RBBP9 RBBP9 O75884 Serine hydrolase RBBP9 chr20 GO:0016787 Not Cancer Driver No 17 0.091 6 0 0.0 0
RCE1 RCE1 Q9Y256 CAAX prenyl protease 2 chr11 GO:0016787 Not Cancer Driver No 40 0.122 0 0 0.0 0
REN REN P00797 Renin chr1 GO:0016787 Not Cancer Driver No 60 0.148 10 0 0.0 3
RERGL RERGL Q9H628 Ras-related and estrogen-regulated growth inhibitor-like protein chr12 GO:0016787 Not Cancer Driver No 57 0.278 0 0 0.0 0
RERG_ENST00000538313 RERG Q96A58 Ras-related and estrogen-regulated growth inhibitor chr12 GO:0016787 Not Cancer Driver No 42 0.211 39 10 0.256 0
RGN RGN Q15493 Regucalcin chrX GO:0016787 Not Cancer Driver No 38 0.127 14 3 0.214 0
RHOA RHOA P61586 Transforming protein RhoA chr3 GO:0016787 Census, Compendium Yes 99 0.513 46 13 0.283 2
RIDA RIDA P52758 2-iminobutanoate/2-iminopropanoate deaminase chr8 GO:0016787 Not Cancer Driver No 20 0.146 3 0 0.0 0
RIOK1 RIOK1 Q9BRS2 Serine/threonine-protein kinase RIO1 chr6 GO:0016787 Not Cancer Driver No 69 0.121 301 37 0.123 0
RIT1_ENST00000368323 RIT1 Q92963 GTP-binding protein Rit1 chr1 GO:0016787 Not Cancer Driver No 34 0.155 43 3 0.07 5
RIT2 RIT2 Q99578 GTP-binding protein Rit2 chr18 GO:0016787 Not Cancer Driver No 74 0.341 29 11 0.379 0
RNASE1_ENST00000412779 RNASE1 P07998 Ribonuclease pancreatic chr14 GO:0016787 Not Cancer Driver No 17 0.109 49 11 0.224 0
RNASE2 RNASE2 P10153 Non-secretory ribonuclease chr14 GO:0016787 Not Cancer Driver No 30 0.186 20 4 0.2 0
RNASE4_ENST00000555597 RNASE4 P34096 Ribonuclease 4 chr14 GO:0016787 Not Cancer Driver No 24 0.163 9 2 0.222 0
RNASE8 RNASE8 Q8TDE3 Ribonuclease 8 chr14 GO:0016787 Not Cancer Driver No 18 0.117 17 2 0.118 0
RNASEH1 RNASEH1 O60930 Ribonuclease H1 chr2 GO:0016787 Not Cancer Driver No 33 0.115 124 20 0.161 2
RNASEH2A RNASEH2A O75792 Ribonuclease H2 subunit A chr19 GO:0016787 Not Cancer Driver No 42 0.14 31 3 0.097 7
RNASET2_ENST00000476238 RNASET2 O00584 Ribonuclease T2 chr6 GO:0016787 Not Cancer Driver No 32 0.125 37 3 0.081 1
RNGTT RNGTT O60942 mRNA-capping enzyme chr6 GO:0016787 Not Cancer Driver No 69 0.116 112 12 0.107 0
RNPEP RNPEP Q9H4A4 Aminopeptidase B chr1 GO:0016787 Not Cancer Driver No 60 0.092 86 4 0.047 0
RNPEPL1 RNPEPL1 Q9HAU8 Aminopeptidase RNPEPL1 chr2 GO:0016787 Not Cancer Driver No 55 0.076 82 2 0.024 0
RPAP2 RPAP2 Q8IXW5 Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 chr1 GO:0016787 Not Cancer Driver No 56 0.092 293 25 0.085 0
RPE65 RPE65 Q16518 Retinoid isomerohydrolase chr1 GO:0016787 Not Cancer Driver No 109 0.205 10 1 0.1 44
RPP14_ENST00000295959 RPP14 O95059 Ribonuclease P protein subunit p14 chr3 GO:0016787 Not Cancer Driver No 8 0.065 0 0 0.0 0
RPP21_ENST00000442966 RPP21 Q9H633 Ribonuclease P protein subunit p21 chr6 GO:0016787 Not Cancer Driver No 16 0.104 51 4 0.078 0
RPP25 RPP25 Q9BUL9 Ribonuclease P protein subunit p25 chr15 GO:0016787 Not Cancer Driver No 11 0.055 162 11 0.068 0
RPP30_ENST00000371703 RPP30 P78346 Ribonuclease P protein subunit p30 chr10 GO:0016787 Not Cancer Driver No 28 0.104 21 2 0.095 0
RPP38_ENST00000378202 RPP38 P78345 Ribonuclease P protein subunit p38 chr10 GO:0016787 Not Cancer Driver No 36 0.127 118 19 0.161 0
RPP40 RPP40 O75818 Ribonuclease P protein subunit p40 chr6 GO:0016787 Not Cancer Driver No 51 0.14 5 0 0.0 0
SACM1L SACM1L Q9NTJ5 Phosphatidylinositol-3-phosphatase SAC1 chr3 GO:0016787 Not Cancer Driver No 41 0.07 0 0 0.0 0
SAMHD1 SAMHD1 Q9Y3Z3 Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 chr20 GO:0016787 Not Cancer Driver No 104 0.166 91 14 0.154 13
SARM1 SARM1 Q6SZW1 NAD(+) hydrolase SARM1 chr17 GO:0016787 Not Cancer Driver No 36 0.05 80 4 0.05 0
SBF1_ENST00000348911 SBF1 O95248 Myotubularin-related protein 5 chr22 GO:0016787 Not Cancer Driver No 210 0.112 632 63 0.1 2
SCPEP1 SCPEP1 Q9HB40 Retinoid-inducible serine carboxypeptidase chr17 GO:0016787 Not Cancer Driver No 46 0.102 1 0 0.0 0
SCRN1_ENST00000242059 SCRN1 Q12765 Secernin-1 chr7 GO:0016787 Not Cancer Driver No 73 0.176 112 21 0.188 0
SCRN2 SCRN2 Q96FV2 Secernin-2 chr17 GO:0016787 Not Cancer Driver No 65 0.153 145 24 0.166 0
SCRN3 SCRN3 Q0VDG4 Secernin-3 chr2 GO:0016787 Not Cancer Driver No 55 0.13 42 3 0.071 0
SENP1 SENP1 Q9P0U3 Sentrin-specific protease 1 chr12 GO:0016787 Not Cancer Driver No 64 0.099 355 44 0.124 0
SENP2 SENP2 Q9HC62 Sentrin-specific protease 2 chr3 GO:0016787 Not Cancer Driver No 73 0.124 285 38 0.133 0
SENP3_ENST00000429205 SENP3 Q9H4L4 Sentrin-specific protease 3 chr17 GO:0016787 Not Cancer Driver No 53 0.092 288 30 0.104 0
SENP5 SENP5 Q96HI0 Sentrin-specific protease 5 chr3 GO:0016787 Not Cancer Driver No 85 0.113 293 34 0.116 0
SENP6 SENP6 Q9GZR1 Sentrin-specific protease 6 chr6 GO:0016787 Not Cancer Driver No 120 0.108 612 59 0.096 0
SENP7 SENP7 Q9BQF6 Sentrin-specific protease 7 chr3 GO:0016787 Not Cancer Driver No 149 0.142 523 73 0.14 0
SENP8 SENP8 Q96LD8 Sentrin-specific protease 8 chr15 GO:0016787 Not Cancer Driver No 16 0.075 0 0 0.0 0
SERHL2 SERHL2 Q9H4I8 Serine hydrolase-like protein 2 chr22 GO:0016787 Not Cancer Driver No 25 0.08 0 0 0.0 0
SETMAR SETMAR Q53H47 Histone-lysine N-methyltransferase SETMAR chr3 GO:0016787 Not Cancer Driver No 62 0.091 154 12 0.078 0
SETX SETX Q7Z333 Probable helicase senataxin chr9 GO:0016787 Not Cancer Driver No 342 0.128 1240 156 0.126 20
SGPP1 SGPP1 Q9BX95 Sphingosine-1-phosphate phosphatase 1 chr14 GO:0016787 Not Cancer Driver No 48 0.109 116 1 0.009 0
SGPP2 SGPP2 Q8IWX5 Sphingosine-1-phosphate phosphatase 2 chr2 GO:0016787 Not Cancer Driver No 44 0.11 42 0 0.0 0
SGSH SGSH P51688 N-sulphoglucosamine sulphohydrolase chr17 GO:0016787 Not Cancer Driver No 45 0.09 44 2 0.045 56
SHPRH SHPRH Q149N8 E3 ubiquitin-protein ligase SHPRH chr6 GO:0016787 Not Cancer Driver No 227 0.135 359 51 0.142 0
SI SI P14410 Sucrase-isomaltase, intestinal chr3 GO:0016787 Not Cancer Driver No 691 0.378 144 66 0.458 11
SIAE SIAE Q9HAT2 Sialate O-acetylesterase chr11 GO:0016787 Not Cancer Driver No 53 0.101 10 3 0.3 9
SIGIRR_ENST00000397632 SIGIRR Q6IA17 Single Ig IL-1-related receptor chr11 GO:0016787 Not Cancer Driver No 27 0.066 85 4 0.047 0
SIRT1 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 GO:0016787 Not Cancer Driver No 70 0.094 435 31 0.071 0
SIRT2 SIRT2 Q8IXJ6 NAD-dependent protein deacetylase sirtuin-2 chr19 GO:0016787 Not Cancer Driver No 56 0.144 85 17 0.2 0
SIRT3 SIRT3 Q9NTG7 NAD-dependent protein deacetylase sirtuin-3, mitochondrial chr11 GO:0016787 Not Cancer Driver No 33 0.083 60 2 0.033 0
SIRT4 SIRT4 Q9Y6E7 NAD-dependent protein lipoamidase sirtuin-4, mitochondrial chr12 GO:0016787 Not Cancer Driver No 46 0.146 4 0 0.0 0
SIRT5 SIRT5 Q9NXA8 NAD-dependent protein deacylase sirtuin-5, mitochondrial chr6 GO:0016787 Not Cancer Driver No 41 0.132 55 7 0.127 0
SIRT6 SIRT6 Q8N6T7 NAD-dependent protein deacylase sirtuin-6 chr19 GO:0016787 Not Cancer Driver No 33 0.093 164 12 0.073 0
SIRT7 SIRT7 Q9NRC8 NAD-dependent protein deacetylase sirtuin-7 chr17 GO:0016787 Not Cancer Driver No 48 0.12 163 15 0.092 0
SKIV2L SKIV2L Q15477 Helicase SKI2W chr6 GO:0016787 Not Cancer Driver No 140 0.112 390 54 0.138 1
SLC25A42 SLC25A42 Q86VD7 Mitochondrial coenzyme A transporter SLC25A42 chr19 GO:0016787 Not Cancer Driver No 42 0.132 12 2 0.167 1
SLX1B SLX1B Q9BQ83 Structure-specific endonuclease subunit SLX1 chr16 GO:0016787 Not Cancer Driver No 3 0.011 80 1 0.013 0
SMARCA1_ENST00000371122 SMARCA1 P28370 Probable global transcription activator SNF2L1 chrX GO:0016787 Compendium Yes 143 0.136 309 41 0.133 0
SMARCAL1 SMARCAL1 Q9NZC9 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 chr2 GO:0016787 Not Cancer Driver No 128 0.134 335 49 0.146 11
SMPD1 SMPD1 P17405 Sphingomyelin phosphodiesterase chr11 GO:0016787 Not Cancer Driver No 93 0.147 51 4 0.078 111
SMPD2 SMPD2 O60906 Sphingomyelin phosphodiesterase 2 chr6 GO:0016787 Not Cancer Driver No 45 0.106 48 5 0.104 0
SMPD3 SMPD3 Q9NY59 Sphingomyelin phosphodiesterase 3 chr16 GO:0016787 Not Cancer Driver No 92 0.14 224 29 0.129 0
SMPD4 SMPD4 Q9NXE4 Sphingomyelin phosphodiesterase 4 chr2 GO:0016787 Not Cancer Driver No 114 0.132 80 12 0.15 1
SMPDL3A SMPDL3A Q92484 Acid sphingomyelinase-like phosphodiesterase 3a chr6 GO:0016787 Not Cancer Driver No 56 0.124 36 3 0.083 0
SMPDL3B SMPDL3B Q92485 Acid sphingomyelinase-like phosphodiesterase 3b chr1 GO:0016787 Not Cancer Driver No 61 0.134 22 7 0.318 0
SMUG1 SMUG1 Q53HV7 Single-strand selective monofunctional uracil DNA glycosylase chr12 GO:0016787 Not Cancer Driver No 33 0.122 46 2 0.043 0
SPACA3 SPACA3 Q8IXA5 Sperm acrosome membrane-associated protein 3 chr17 GO:0016787 Not Cancer Driver No 52 0.242 0 0 0.0 0
SPACA5_ENST00000376940 SPACA5B Q96QH8 Sperm acrosome-associated protein 5 chrX GO:0016787 Not Cancer Driver No 6 0.038 0 0 0.0 0
SPAG1_ENST00000251809 SPAG1 Q07617 Sperm-associated antigen 1 chr8 GO:0016787 Not Cancer Driver No 106 0.114 385 46 0.119 0
SPAM1_ENST00000439500 SPAM1 P38567 Hyaluronidase PH-20 chr7 GO:0016787 Not Cancer Driver No 172 0.338 5 1 0.2 0
SPG7 SPG7 Q9UQ90 Paraplegin chr16 GO:0016787 Not Cancer Driver No 97 0.122 181 29 0.16 4
SPO11 SPO11 Q9Y5K1 Meiotic recombination protein SPO11 chr20 GO:0016787 Not Cancer Driver No 59 0.149 26 5 0.192 0
SPPL2A SPPL2A Q8TCT8 Signal peptide peptidase-like 2A chr15 GO:0016787 Not Cancer Driver No 55 0.106 3 0 0.0 0
SPPL2B SPPL2B Q8TCT7 Signal peptide peptidase-like 2B chr19 GO:0016787 Not Cancer Driver No 68 0.115 99 17 0.172 0
SPPL2C SPPL2C Q8IUH8 Signal peptide peptidase-like 2C chr17 GO:0016787 Not Cancer Driver No 110 0.161 216 45 0.208 0
SPPL3 SPPL3 Q8TCT6 Signal peptide peptidase-like 3 chr12 GO:0016787 Not Cancer Driver No 45 0.117 23 0 0.0 0
SSH1 SSH1 Q8WYL5 Protein phosphatase Slingshot homolog 1 chr12 GO:0016787 Not Cancer Driver No 129 0.123 658 85 0.129 0
SSH2_ENST00000269033 SSH2 Q76I76 Protein phosphatase Slingshot homolog 2 chr17 GO:0016787 Not Cancer Driver No 161 0.113 999 117 0.117 0
SSH3 SSH3 Q8TE77 Protein phosphatase Slingshot homolog 3 chr11 GO:0016787 Not Cancer Driver No 96 0.146 354 49 0.138 0
SSU72 SSU72 Q9NP77 RNA polymerase II subunit A C-terminal domain phosphatase SSU72 chr1 GO:0016787 Not Cancer Driver No 18 0.093 65 3 0.046 0
SSU72P2 SSU72P2 A0A1W2PQD8 RNA polymerase II subunit A C-terminal domain phosphatase SSU72 chr11 GO:0016787 Not Cancer Driver No 3 0.015 15 0 0.0 0
SSU72P3 SSU72P3 A0A1W2PQJ5 RNA polymerase II subunit A C-terminal domain phosphatase SSU72 chr11 GO:0016787 Not Cancer Driver No 2 0.01 17 0 0.0 0
SSU72P8 SSU72P8 A0A1W2PR75 RNA polymerase II subunit A C-terminal domain phosphatase SSU72 chr7 GO:0016787 Not Cancer Driver No 8 0.041 8 0 0.0 0
STAMBPL1_ENST00000371924 STAMBPL1 Q96FJ0 AMSH-like protease chr10 GO:0016787 Not Cancer Driver No 48 0.11 70 7 0.1 0
STAMBP_ENST00000339566 STAMBP O95630 STAM-binding protein chr2 GO:0016787 Not Cancer Driver No 51 0.12 139 16 0.115 6
STS STS P08842 Steryl-sulfatase chrX GO:0016787 Not Cancer Driver No 113 0.194 48 7 0.146 7
STYX STYX Q8WUJ0 Serine/threonine/tyrosine-interacting protein chr14 GO:0016787 Not Cancer Driver No 20 0.09 30 2 0.067 0
STYXL1_ENST00000359697 STYXL1 Q9Y6J8 Serine/threonine/tyrosine-interacting-like protein 1 chr7 GO:0016787 Not Cancer Driver No 55 0.176 18 3 0.167 0
SULF1_ENST00000458141 SULF1 Q8IWU6 Extracellular sulfatase Sulf-1 chr8 GO:0016787 Not Cancer Driver No 246 0.282 269 71 0.264 0
SULF2_ENST00000484875 SULF2 Q8IWU5 Extracellular sulfatase Sulf-2 chr20 GO:0016787 Not Cancer Driver No 145 0.167 142 18 0.127 0
SYNJ1 SYNJ1 O43426 Synaptojanin-1 chr21 GO:0016787 Not Cancer Driver No 208 0.132 584 76 0.13 3
SYNJ2 SYNJ2 O15056 Synaptojanin-2 chr6 GO:0016787 Not Cancer Driver No 189 0.126 545 70 0.128 0
TARS2 TARS2 Q9BW92 Threonine--tRNA ligase, mitochondrial chr1 GO:0016787 Not Cancer Driver No 112 0.156 53 10 0.189 1
TASP1 TASP1 Q9H6P5 Threonine aspartase 1 chr20 GO:0016787 Not Cancer Driver No 59 0.14 81 11 0.136 1
TDG TDG Q13569 G/T mismatch-specific thymine DNA glycosylase chr12 GO:0016787 Not Cancer Driver No 75 0.183 185 31 0.168 0
TDP1_ENST00000393454 TDP1 Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 chr14 GO:0016787 Not Cancer Driver No 81 0.133 179 25 0.14 1
TDP2 TDP2 O95551 Tyrosyl-DNA phosphodiesterase 2 chr6 GO:0016787 Not Cancer Driver No 55 0.152 80 10 0.125 0
TEFM TEFM Q96QE5 Transcription elongation factor, mitochondrial chr17 GO:0016787 Not Cancer Driver No 37 0.103 26 5 0.192 0
TEX30 TEX30 Q5JUR7 Testis-expressed protein 30 chr13 GO:0016787 Not Cancer Driver No 41 0.181 7 2 0.286 0
TFR2_ENST00000223051 TFR2 Q9UP52 Transferrin receptor protein 2 chr7 GO:0016787 Not Cancer Driver No 94 0.117 168 20 0.119 3
TFRC_ENST00000392396 TFRC P02786 Transferrin receptor protein 1 chr3 GO:0016787 Census Yes 89 0.117 80 6 0.075 1
TGM2 TGM2 P21980 Protein-glutamine gamma-glutamyltransferase 2 chr20 GO:0016787 Not Cancer Driver No 123 0.179 107 26 0.243 0
THEM4 THEM4 Q5T1C6 Acyl-coenzyme A thioesterase THEM4 chr1 GO:0016787 Not Cancer Driver No 19 0.079 14 0 0.0 0
THEM5 THEM5 Q8N1Q8 Acyl-coenzyme A thioesterase THEM5 chr1 GO:0016787 Not Cancer Driver No 39 0.158 1 0 0.0 0
THSD4 THSD4 Q6ZMP0 Thrombospondin type-1 domain-containing protein 4 chr15 GO:0016787 Not Cancer Driver No 172 0.169 410 62 0.151 0
THTPA THTPA Q9BU02 Thiamine-triphosphatase chr14 GO:0016787 Not Cancer Driver No 19 0.083 56 4 0.071 0
TICAM1 TICAM1 Q8IUC6 TIR domain-containing adapter molecule 1 chr19 GO:0016787 Not Cancer Driver No 92 0.129 443 66 0.149 1
TICAM2 TICAM2 Q86XR7 TIR domain-containing adapter molecule 2 chr5 GO:0016787 Not Cancer Driver No 35 0.149 88 10 0.114 0
TIGAR TIGAR Q9NQ88 Fructose-2,6-bisphosphatase TIGAR chr12 GO:0016787 Not Cancer Driver No 44 0.163 39 9 0.231 0
TIRAP_ENST00000392680 TIRAP P58753 Toll/interleukin-1 receptor domain-containing adapter protein chr11 GO:0016787 Not Cancer Driver No 28 0.127 80 6 0.075 0
TLR10_ENST00000508334 TLR10 Q9BXR5 Toll-like receptor 10 chr4 GO:0016787 Not Cancer Driver No 122 0.15 9 1 0.111 0
TLR1_ENST00000502213 TLR1 Q15399 Toll-like receptor 1 chr4 GO:0016787 Not Cancer Driver No 107 0.136 1 0 0.0 0
TLR2 TLR2 O60603 Toll-like receptor 2 chr4 GO:0016787 Not Cancer Driver No 108 0.138 0 0 0.0 0
TLR3 TLR3 O15455 Toll-like receptor 3 chr4 GO:0016787 Not Cancer Driver No 123 0.136 0 0 0.0 1
TLR4_ENST00000355622 TLR4 O00206 Toll-like receptor 4 chr9 GO:0016787 Not Cancer Driver No 292 0.348 0 0 0.0 0
TLR5_ENST00000366881 TLR5 O60602 Toll-like receptor 5 chr1 GO:0016787 Not Cancer Driver No 148 0.172 16 3 0.188 0
TLR6 TLR6 Q9Y2C9 Toll-like receptor 6 chr4 GO:0016787 Not Cancer Driver No 99 0.124 1 0 0.0 0
TLR7 TLR7 Q9NYK1 Toll-like receptor 7 chrX GO:0016787 Not Cancer Driver No 182 0.173 14 1 0.071 1
TLR8_ENST00000218032 TLR8 Q9NR97 Toll-like receptor 8 chrX GO:0016787 Not Cancer Driver No 180 0.173 30 7 0.233 0
TLR9 TLR9 Q9NR96 Toll-like receptor 9 chr3 GO:0016787 Not Cancer Driver No 141 0.137 35 3 0.086 0
TMEM62 TMEM62 Q0P6H9 Transmembrane protein 62 chr15 GO:0016787 Not Cancer Driver No 66 0.103 39 1 0.026 0
TMEM86A TMEM86A Q8N2M4 Lysoplasmalogenase-like protein TMEM86A chr11 GO:0016787 Not Cancer Driver No 29 0.121 0 0 0.0 0
TMEM86B TMEM86B Q8N661 Lysoplasmalogenase chr19 GO:0016787 Not Cancer Driver No 15 0.066 1 0 0.0 0
TMPPE TMPPE Q6ZT21 Transmembrane protein with metallophosphoesterase domain chr3 GO:0016787 Not Cancer Driver No 47 0.104 19 1 0.053 0
TNFAIP3 TNFAIP3 P21580 Tumor necrosis factor alpha-induced protein 3 chr6 GO:0016787 Census, Compendium Yes 98 0.124 231 33 0.143 1
TOE1 TOE1 Q96GM8 Target of EGR1 protein 1 chr1 GO:0016787 Not Cancer Driver No 44 0.086 210 22 0.105 10
TP53RK TP53RK Q96S44 EKC/KEOPS complex subunit TP53RK chr20 GO:0016787 Not Cancer Driver No 20 0.079 51 2 0.039 3
TPP1 TPP1 O14773 Tripeptidyl-peptidase 1 chr11 GO:0016787 Not Cancer Driver No 67 0.119 92 7 0.076 37
TPP2_ENST00000376065 TPP2 P29144 Tripeptidyl-peptidase 2 chr13 GO:0016787 Not Cancer Driver No 147 0.118 218 40 0.183 1
TPTE2 TPTE2 Q6XPS3 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2 chr13 GO:0016787 Not Cancer Driver No 210 0.402 33 13 0.394 0
TREH TREH O43280 Trehalase chr11 GO:0016787 Not Cancer Driver No 47 0.081 34 3 0.088 0
TREX1_ENST00000625293 TREX1 Q9NSU2 Three-prime repair exonuclease 1 chr3 GO:0016787 Not Cancer Driver No 26 0.083 98 10 0.102 18
TREX2_ENST00000370231 TREX2 Q9BQ50 Three prime repair exonuclease 2 chrX GO:0016787 Not Cancer Driver No 33 0.14 23 6 0.261 0
TRHDE TRHDE Q9UKU6 Thyrotropin-releasing hormone-degrading ectoenzyme chr12 GO:0016787 Not Cancer Driver No 346 0.338 104 11 0.106 0
TRPM2_ENST00000397928 TRPM2 O94759 Transient receptor potential cation channel subfamily M member 2 chr21 GO:0016787 Not Cancer Driver No 286 0.19 266 44 0.165 0
TSEN2 TSEN2 Q8NCE0 tRNA-splicing endonuclease subunit Sen2 chr3 GO:0016787 Not Cancer Driver No 54 0.116 153 17 0.111 1
TSEN34_ENST00000396383 TSEN34 Q9BSV6 tRNA-splicing endonuclease subunit Sen34 chr19 GO:0016787 Not Cancer Driver No 40 0.129 176 22 0.125 1
TTF2 TTF2 Q9UNY4 Transcription termination factor 2 chr1 GO:0016787 Not Cancer Driver No 118 0.102 550 50 0.091 0
UCHL3 UCHL3 P15374 Ubiquitin carboxyl-terminal hydrolase isozyme L3 chr13 GO:0016787 Not Cancer Driver No 26 0.113 61 3 0.049 0
UFSP2 UFSP2 Q9NUQ7 Ufm1-specific protease 2 chr4 GO:0016787 Not Cancer Driver No 53 0.113 22 3 0.136 2
UNG UNG P13051 Uracil-DNA glycosylase chr12 GO:0016787 Not Cancer Driver No 34 0.109 96 13 0.135 1
UPB1 UPB1 Q9UBR1 Beta-ureidopropionase chr22 GO:0016787 Not Cancer Driver No 66 0.172 22 7 0.318 8
USB1 USB1 Q9BQ65 U6 snRNA phosphodiesterase 1 chr16 GO:0016787 Not Cancer Driver No 28 0.106 76 5 0.066 0
USP13 USP13 Q92995 Ubiquitin carboxyl-terminal hydrolase 13 chr3 GO:0016787 Not Cancer Driver No 121 0.14 224 42 0.188 0
USP15 USP15 Q9Y4E8 Ubiquitin carboxyl-terminal hydrolase 15 chr12 GO:0016787 Not Cancer Driver No 136 0.139 259 39 0.151 0
USP18 USP18 Q9UMW8 Ubl carboxyl-terminal hydrolase 18 chr22 GO:0016787 Not Cancer Driver No 34 0.091 29 8 0.276 0
USP19_ENST00000398888 USP19 O94966 Ubiquitin carboxyl-terminal hydrolase 19 chr3 GO:0016787 Not Cancer Driver No 161 0.122 539 68 0.126 0
USP21_ENST00000289865 USP21 Q9UK80 Ubiquitin carboxyl-terminal hydrolase 21 chr1 GO:0016787 Not Cancer Driver No 95 0.168 230 47 0.204 0
USP27X USP27X A6NNY8 Ubiquitin carboxyl-terminal hydrolase 27 chrX GO:0016787 Not Cancer Driver No 31 0.071 69 3 0.043 1
USP43 USP43 Q70EL4 Ubiquitin carboxyl-terminal hydrolase 43 chr17 GO:0016787 Not Cancer Driver No 134 0.119 562 56 0.1 0
USP7 USP7 Q93009 Ubiquitin carboxyl-terminal hydrolase 7 chr16 GO:0016787 Not Cancer Driver No 170 0.154 215 45 0.209 0
USP9X_ENST00000378308 USP9X Q93008 Probable ubiquitin carboxyl-terminal hydrolase FAF-X chrX GO:0016787 Census, Compendium Yes 339 0.133 405 51 0.126 1
USPL1 USPL1 Q5W0Q7 SUMO-specific isopeptidase USPL1 chr13 GO:0016787 Not Cancer Driver No 107 0.098 578 55 0.095 0
VARS VARS1 P26640 Valine--tRNA ligase chr6 GO:0016787 Not Cancer Driver No 145 0.115 251 26 0.104 0
VARS2_ENST00000321897 VARS2 Q5ST30 Valine--tRNA ligase, mitochondrial chr6 GO:0016787 Not Cancer Driver No 111 0.104 253 21 0.083 3
VASH1 VASH1 Q7L8A9 Tubulinyl-Tyr carboxypeptidase 1 chr14 GO:0016787 Not Cancer Driver No 39 0.107 215 18 0.084 0
VASH2 VASH2 Q86V25 Tubulinyl-Tyr carboxypeptidase 2 chr1 GO:0016787 Not Cancer Driver No 32 0.09 106 9 0.085 0
VNN1 VNN1 O95497 Pantetheinase chr6 GO:0016787 Not Cancer Driver No 88 0.172 20 5 0.25 0
VNN2 VNN2 O95498 Pantetheine hydrolase VNN2 chr6 GO:0016787 Not Cancer Driver No 96 0.185 15 3 0.2 0
WDYHV1 NTAQ1 Q96HA8 Protein N-terminal glutamine amidohydrolase chr8 GO:0016787 Not Cancer Driver No 38 0.185 26 3 0.115 0
XPNPEP2 XPNPEP2 O43895 Xaa-Pro aminopeptidase 2 chrX GO:0016787 Not Cancer Driver No 114 0.169 16 2 0.125 0
XPNPEP3 XPNPEP3 Q9NQH7 Xaa-Pro aminopeptidase 3 chr22 GO:0016787 Not Cancer Driver No 64 0.126 128 14 0.109 1
XRCC1 XRCC1 P18887 DNA repair protein XRCC1 chr19 GO:0016787 Not Cancer Driver No 85 0.134 426 53 0.124 1
XRCC3_ENST00000352127 XRCC3 O43542 DNA repair protein XRCC3 chr14 GO:0016787 Not Cancer Driver No 24 0.069 35 2 0.057 1
XRCC5_ENST00000392132 XRCC5 P13010 X-ray repair cross-complementing protein 5 chr2 GO:0016787 Not Cancer Driver No 87 0.119 118 11 0.093 0
XRCC6 XRCC6 P12956 X-ray repair cross-complementing protein 6 chr22 GO:0016787 Not Cancer Driver No 66 0.108 140 12 0.086 0
XRN1 XRN1 Q8IZH2 5'-3' exoribonuclease 1 chr3 GO:0016787 Not Cancer Driver No 213 0.125 577 65 0.113 0
XRN2 XRN2 Q9H0D6 5'-3' exoribonuclease 2 chr20 GO:0016787 Not Cancer Driver No 129 0.136 427 63 0.148 0
YME1L1 YME1L1 Q96TA2 ATP-dependent zinc metalloprotease YME1L1 chr10 GO:0016787 Not Cancer Driver No 112 0.145 136 14 0.103 1
YOD1 YOD1 Q5VVQ6 Ubiquitin thioesterase OTU1 chr1 GO:0016787 Not Cancer Driver No 30 0.086 120 6 0.05 0
ZBP1 ZBP1 Q9H171 Z-DNA-binding protein 1 chr20 GO:0016787 Not Cancer Driver No 97 0.226 385 80 0.208 0
ZC3H12A ZC3H12A Q5D1E8 Endoribonuclease ZC3H12A chr1 GO:0016787 Not Cancer Driver No 90 0.15 396 44 0.111 0
ZGRF1 ZGRF1 Q86YA3 Protein ZGRF1 chr4 GO:0016787 Not Cancer Driver No 216 0.103 881 95 0.108 0
ZMPSTE24 ZMPSTE24 O75844 CAAX prenyl protease 1 homolog chr1 GO:0016787 Not Cancer Driver No 67 0.141 23 0 0.0 3