Total number of protein in "GO:0016741" GO term: 155
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ALDH1L1_ENST00000393434 | ALDH1L1 | O75891 | Cytosolic 10-formyltetrahydrofolate dehydrogenase | chr3 | GO:0016741 | Not Cancer Driver | No | 159 | 0.176 | 87 | 19 | 0.218 | 0 |
| ALDH1L2 | ALDH1L2 | Q3SY69 | Mitochondrial 10-formyltetrahydrofolate dehydrogenase | chr12 | GO:0016741 | Not Cancer Driver | No | 108 | 0.117 | 81 | 12 | 0.148 | 0 |
| ALKBH8_ENST00000389568 | ALKBH8 | Q96BT7 | Alkylated DNA repair protein alkB homolog 8 | chr11 | GO:0016741 | Not Cancer Driver | No | 50 | 0.075 | 189 | 12 | 0.063 | 0 |
| AMT | AMT | P48728 | Aminomethyltransferase, mitochondrial | chr3 | GO:0016741 | Not Cancer Driver | No | 37 | 0.092 | 33 | 6 | 0.182 | 11 |
| AP000812.4 | TOMT | A0A2R8Y5M8 | Catechol O-methyltransferase | chr11 | GO:0016741 | Not Cancer Driver | No | 16 | 0.062 | 0 | 0 | 0.0 | 0 |
| ARMT1 | ARMT1 | Q9H993 | Damage-control phosphatase ARMT1 | chr6 | GO:0016741 | Not Cancer Driver | No | 53 | 0.12 | 1 | 0 | 0.0 | 0 |
| AS3MT | AS3MT | Q9HBK9 | Arsenite methyltransferase | chr10 | GO:0016741 | Not Cancer Driver | No | 36 | 0.096 | 4 | 0 | 0.0 | 0 |
| ASH1L_ENST00000368346 | ASH1L | Q9NR48 | Histone-lysine N-methyltransferase ASH1L | chr1 | GO:0016741 | Not Cancer Driver | No | 415 | 0.14 | 1858 | 256 | 0.138 | 1 |
| ASH2L | ASH2L | Q9UBL3 | Set1/Ash2 histone methyltransferase complex subunit ASH2 | chr8 | GO:0016741 | Not Cancer Driver | No | 95 | 0.151 | 293 | 39 | 0.133 | 0 |
| ASMT_ENST00000381229 | ASMT | P46597 | Acetylserotonin O-methyltransferase | chrX | GO:0016741 | Not Cancer Driver | No | 67 | 0.194 | 1 | 0 | 0.0 | 0 |
| ATIC | ATIC | P31939 | Bifunctional purine biosynthesis protein ATIC | chr2 | GO:0016741 | Census | Yes | 74 | 0.125 | 25 | 1 | 0.04 | 1 |
| BHMT | BHMT | Q93088 | Betaine--homocysteine S-methyltransferase 1 | chr5 | GO:0016741 | Not Cancer Driver | No | 78 | 0.192 | 93 | 12 | 0.129 | 0 |
| BHMT2 | BHMT2 | Q9H2M3 | S-methylmethionine--homocysteine S-methyltransferase BHMT2 | chr5 | GO:0016741 | Not Cancer Driver | No | 54 | 0.149 | 30 | 4 | 0.133 | 0 |
| BUD23_ENST00000265758 | BUD23 | O43709 | Probable 18S rRNA (guanine-N(7))-methyltransferase | chr7 | GO:0016741 | Not Cancer Driver | No | 41 | 0.146 | 83 | 11 | 0.133 | 0 |
| CAD | CAD | P27708 | CAD protein | chr2 | GO:0016741 | Not Cancer Driver | No | 287 | 0.129 | 368 | 52 | 0.141 | 1 |
| CAMKMT | CAMKMT | Q7Z624 | Calmodulin-lysine N-methyltransferase | chr2 | GO:0016741 | Not Cancer Driver | No | 34 | 0.105 | 31 | 0 | 0.0 | 0 |
| CARM1 | CARM1 | Q86X55 | Histone-arginine methyltransferase CARM1 | chr19 | GO:0016741 | Not Cancer Driver | No | 62 | 0.102 | 102 | 10 | 0.098 | 0 |
| CARNMT1 | CARNMT1 | Q8N4J0 | Carnosine N-methyltransferase | chr9 | GO:0016741 | Not Cancer Driver | No | 42 | 0.103 | 75 | 1 | 0.013 | 0 |
| CMTR1 | CMTR1 | Q8N1G2 | Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 | chr6 | GO:0016741 | Not Cancer Driver | No | 81 | 0.097 | 176 | 20 | 0.114 | 0 |
| CMTR2 | CMTR2 | Q8IYT2 | Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 | chr16 | GO:0016741 | Compendium | Yes | 101 | 0.131 | 10 | 2 | 0.2 | 0 |
| COMT | COMT | P21964 | Catechol O-methyltransferase | chr22 | GO:0016741 | Not Cancer Driver | No | 21 | 0.077 | 5 | 0 | 0.0 | 0 |
| COQ3 | COQ3 | Q9NZJ6 | Ubiquinone biosynthesis O-methyltransferase, mitochondrial | chr6 | GO:0016741 | Not Cancer Driver | No | 47 | 0.127 | 22 | 5 | 0.227 | 0 |
| COQ5 | COQ5 | Q5HYK3 | 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial | chr12 | GO:0016741 | Not Cancer Driver | No | 45 | 0.138 | 15 | 2 | 0.133 | 0 |
| CXXC1_ENST00000285106 | CXXC1 | Q9P0U4 | CXXC-type zinc finger protein 1 | chr18 | GO:0016741 | Not Cancer Driver | No | 115 | 0.175 | 366 | 65 | 0.178 | 0 |
| DIMT1 | DIMT1 | Q9UNQ2 | Probable dimethyladenosine transferase | chr5 | GO:0016741 | Not Cancer Driver | No | 28 | 0.089 | 37 | 2 | 0.054 | 0 |
| DNMT1_ENST00000340748 | DNMT1 | P26358 | DNA (cytosine-5)-methyltransferase 1 | chr19 | GO:0016741 | Not Cancer Driver | No | 203 | 0.126 | 702 | 78 | 0.111 | 4 |
| DNMT3A | DNMT3A | Q9Y6K1 | DNA (cytosine-5)-methyltransferase 3A | chr2 | GO:0016741 | Census, Compendium | Yes | 194 | 0.213 | 371 | 59 | 0.159 | 16 |
| DNMT3B | DNMT3B | Q9UBC3 | DNA (cytosine-5)-methyltransferase 3B | chr20 | GO:0016741 | Not Cancer Driver | No | 153 | 0.179 | 328 | 71 | 0.216 | 16 |
| DOT1L | DOT1L | Q8TEK3 | Histone-lysine N-methyltransferase, H3 lysine-79 specific | chr19 | GO:0016741 | Compendium | Yes | 178 | 0.116 | 988 | 118 | 0.119 | 0 |
| DPH5 | DPH5 | Q9H2P9 | Diphthine methyl ester synthase | chr1 | GO:0016741 | Not Cancer Driver | No | 25 | 0.088 | 18 | 1 | 0.056 | 0 |
| EHMT1 | EHMT1 | Q9H9B1 | Histone-lysine N-methyltransferase EHMT1 | chr9 | GO:0016741 | Not Cancer Driver | No | 182 | 0.14 | 701 | 97 | 0.138 | 1 |
| EHMT2_ENST00000375537 | EHMT2 | Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | chr6 | GO:0016741 | Not Cancer Driver | No | 142 | 0.117 | 585 | 71 | 0.121 | 0 |
| EMG1 | EMG1 | Q92979 | Ribosomal RNA small subunit methyltransferase NEP1 | chr12 | GO:0016741 | Not Cancer Driver | No | 28 | 0.115 | 58 | 4 | 0.069 | 1 |
| EZH2_ENST00000460911 | EZH2 | Q15910 | Histone-lysine N-methyltransferase EZH2 | chr7 | GO:0016741 | Census, Compendium | Yes | 120 | 0.161 | 284 | 44 | 0.155 | 11 |
| FAM86C1 | FAM86C1P | Q9NVL1 | Putative protein FAM86C1P | chr11 | GO:0016741 | Not Cancer Driver | No | 27 | 0.164 | 10 | 3 | 0.3 | 0 |
| FBL | FBL | P22087 | rRNA 2'-O-methyltransferase fibrillarin | chr19 | GO:0016741 | Not Cancer Driver | No | 46 | 0.143 | 145 | 22 | 0.152 | 0 |
| FBLL1 | FBLL1 | A6NHQ2 | rRNA/tRNA 2'-O-methyltransferase fibrillarin-like protein 1 | chr5 | GO:0016741 | Not Cancer Driver | No | 18 | 0.054 | 140 | 1 | 0.007 | 0 |
| FBXO11 | FBXO11 | Q86XK2 | F-box only protein 11 | chr2 | GO:0016741 | Census, Compendium | Yes | 113 | 0.122 | 242 | 22 | 0.091 | 8 |
| FDXACB1 | FDXACB1 | Q9BRP7 | Ferredoxin-fold anticodon-binding domain-containing protein 1 | chr11 | GO:0016741 | Not Cancer Driver | No | 60 | 0.096 | 26 | 2 | 0.077 | 0 |
| FTCD_ENST00000291670 | FTCD | O95954 | Formimidoyltransferase-cyclodeaminase | chr21 | GO:0016741 | Not Cancer Driver | No | 86 | 0.159 | 44 | 36 | 0.818 | 2 |
| FTSJ1 | FTSJ1 | Q9UET6 | Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase | chrX | GO:0016741 | Not Cancer Driver | No | 44 | 0.134 | 89 | 14 | 0.157 | 0 |
| FTSJ3 | FTSJ3 | Q8IY81 | pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3 | chr17 | GO:0016741 | Not Cancer Driver | No | 103 | 0.122 | 533 | 66 | 0.124 | 0 |
| GAMT_ENST00000252288 | GAMT | Q14353 | Guanidinoacetate N-methyltransferase | chr19 | GO:0016741 | Not Cancer Driver | No | 29 | 0.123 | 12 | 0 | 0.0 | 18 |
| GART_ENST00000381815 | GART | P22102 | Trifunctional purine biosynthetic protein adenosine-3 | chr21 | GO:0016741 | Not Cancer Driver | No | 96 | 0.095 | 50 | 6 | 0.12 | 0 |
| GATM | GATM | P50440 | Glycine amidinotransferase, mitochondrial | chr15 | GO:0016741 | Not Cancer Driver | No | 69 | 0.163 | 33 | 8 | 0.242 | 15 |
| GCSH | GCSH | P23434 | Glycine cleavage system H protein, mitochondrial | chr16 | GO:0016741 | Not Cancer Driver | No | 15 | 0.087 | 25 | 0 | 0.0 | 0 |
| GNMT | GNMT | Q14749 | Glycine N-methyltransferase | chr6 | GO:0016741 | Not Cancer Driver | No | 25 | 0.085 | 0 | 0 | 0.0 | 3 |
| HEMK1_ENST00000455834 | HEMK1 | Q9Y5R4 | MTRF1L release factor glutamine methyltransferase | chr3 | GO:0016741 | Not Cancer Driver | No | 36 | 0.107 | 14 | 0 | 0.0 | 0 |
| HENMT1 | HENMT1 | Q5T8I9 | Small RNA 2'-O-methyltransferase | chr1 | GO:0016741 | Not Cancer Driver | No | 55 | 0.14 | 32 | 6 | 0.188 | 0 |
| HNMT | HNMT | P50135 | Histamine N-methyltransferase | chr2 | GO:0016741 | Not Cancer Driver | No | 40 | 0.137 | 7 | 0 | 0.0 | 2 |
| ICMT | ICMT | O60725 | Protein-S-isoprenylcysteine O-methyltransferase | chr1 | GO:0016741 | Not Cancer Driver | No | 24 | 0.085 | 0 | 0 | 0.0 | 0 |
| INMT | INMT | O95050 | Indolethylamine N-methyltransferase | chr7 | GO:0016741 | Not Cancer Driver | No | 64 | 0.243 | 5 | 0 | 0.0 | 0 |
| KMT2A_ENST00000389506 | KMT2A | Q03164 | Histone-lysine N-methyltransferase 2A | chr11 | GO:0016741 | Census, Compendium | Yes | 446 | 0.112 | 3145 | 338 | 0.107 | 0 |
| KMT2B | KMT2B | Q9UMN6 | Histone-lysine N-methyltransferase 2B | chr19 | GO:0016741 | Compendium | Yes | 378 | 0.139 | 1895 | 227 | 0.12 | 0 |
| KMT2C_ENST00000355193 | KMT2C | Q8NEZ4 | Histone-lysine N-methyltransferase 2C | chr7 | GO:0016741 | Census, Compendium | Yes | 835 | 0.17 | 3599 | 517 | 0.144 | 0 |
| KMT2D | KMT2D | O14686 | Histone-lysine N-methyltransferase 2D | chr12 | GO:0016741 | Census, Compendium | Yes | 773 | 0.14 | 4386 | 552 | 0.126 | 13 |
| KMT5B_ENST00000615954 | KMT5B | Q4FZB7 | Histone-lysine N-methyltransferase KMT5B | chr11 | GO:0016741 | Not Cancer Driver | No | 147 | 0.166 | 659 | 113 | 0.171 | 0 |
| KMT5C | KMT5C | Q86Y97 | Histone-lysine N-methyltransferase KMT5C | chr19 | GO:0016741 | Not Cancer Driver | No | 37 | 0.08 | 142 | 9 | 0.063 | 0 |
| LCMT1 | LCMT1 | Q9UIC8 | Leucine carboxyl methyltransferase 1 | chr16 | GO:0016741 | Not Cancer Driver | No | 43 | 0.129 | 2 | 0 | 0.0 | 0 |
| MECOM_ENST00000494292 | MECOM | Q03112 | Histone-lysine N-methyltransferase MECOM | chr3 | GO:0016741 | Census, Compendium | Yes | 287 | 0.233 | 749 | 159 | 0.212 | 3 |
| MEPCE | MEPCE | Q7L2J0 | 7SK snRNA methylphosphate capping enzyme | chr7 | GO:0016741 | Not Cancer Driver | No | 76 | 0.11 | 446 | 42 | 0.094 | 0 |
| METTL1 | METTL1 | Q9UBP6 | tRNA (guanine-N(7)-)-methyltransferase | chr12 | GO:0016741 | Not Cancer Driver | No | 43 | 0.156 | 89 | 11 | 0.124 | 0 |
| METTL11B | NTMT2 | Q5VVY1 | N-terminal Xaa-Pro-Lys N-methyltransferase 2 | chr1 | GO:0016741 | Not Cancer Driver | No | 22 | 0.078 | 0 | 0 | 0.0 | 0 |
| METTL14 | METTL14 | Q9HCE5 | N6-adenosine-methyltransferase non-catalytic subunit | chr4 | GO:0016741 | Not Cancer Driver | No | 60 | 0.132 | 224 | 26 | 0.116 | 0 |
| METTL15 | METTL15 | A6NJ78 | 12S rRNA N4-methylcytidine (m4C) methyltransferase | chr11 | GO:0016741 | Not Cancer Driver | No | 46 | 0.113 | 92 | 14 | 0.152 | 0 |
| METTL16 | METTL16 | Q86W50 | RNA N6-adenosine-methyltransferase METTL16 | chr17 | GO:0016741 | Not Cancer Driver | No | 55 | 0.098 | 172 | 22 | 0.128 | 0 |
| METTL18 | METTL18 | O95568 | Histidine protein methyltransferase 1 homolog | chr1 | GO:0016741 | Not Cancer Driver | No | 37 | 0.099 | 125 | 8 | 0.064 | 0 |
| METTL2A | METTL2A | Q96IZ6 | tRNA N(3)-methylcytidine methyltransferase METTL2A | chr17 | GO:0016741 | Not Cancer Driver | No | 38 | 0.101 | 79 | 12 | 0.152 | 0 |
| METTL2B | METTL2B | Q6P1Q9 | tRNA N(3)-methylcytidine methyltransferase METTL2B | chr7 | GO:0016741 | Not Cancer Driver | No | 53 | 0.14 | 65 | 9 | 0.138 | 0 |
| METTL3 | METTL3 | Q86U44 | N6-adenosine-methyltransferase catalytic subunit | chr14 | GO:0016741 | Not Cancer Driver | No | 74 | 0.128 | 274 | 29 | 0.106 | 0 |
| METTL4 | METTL4 | Q8N3J2 | N(6)-adenine-specific methyltransferase METTL4 | chr18 | GO:0016741 | Not Cancer Driver | No | 61 | 0.129 | 34 | 4 | 0.118 | 0 |
| METTL5 | METTL5 | Q9NRN9 | rRNA N6-adenosine-methyltransferase METTL5 | chr2 | GO:0016741 | Not Cancer Driver | No | 19 | 0.091 | 0 | 0 | 0.0 | 0 |
| METTL6 | METTL6 | Q8TCB7 | tRNA N(3)-methylcytidine methyltransferase METTL6 | chr3 | GO:0016741 | Not Cancer Driver | No | 38 | 0.134 | 20 | 0 | 0.0 | 0 |
| METTL7B | METTL7B | Q6UX53 | Thiol S-methyltransferase METTL7B | chr12 | GO:0016741 | Not Cancer Driver | No | 35 | 0.143 | 3 | 4 | 1.333 | 0 |
| METTL8_ENST00000638989 | METTL8 | Q9H825 | tRNA N(3)-methylcytidine methyltransferase METTL8, mitochondrial | chr2 | GO:0016741 | Not Cancer Driver | No | 32 | 0.11 | 95 | 11 | 0.116 | 0 |
| METTL9 | METTL9 | Q9H1A3 | Protein-L-histidine N-pros-methyltransferase | chr16 | GO:0016741 | Not Cancer Driver | No | 33 | 0.104 | 7 | 0 | 0.0 | 0 |
| MRM2_ENST00000440306 | MRM2 | Q9UI43 | rRNA methyltransferase 2, mitochondrial | chr7 | GO:0016741 | Not Cancer Driver | No | 37 | 0.15 | 15 | 1 | 0.067 | 1 |
| MRM3 | MRM3 | Q9HC36 | rRNA methyltransferase 3, mitochondrial | chr17 | GO:0016741 | Not Cancer Driver | No | 45 | 0.107 | 83 | 8 | 0.096 | 0 |
| MTFMT | MTFMT | Q96DP5 | Methionyl-tRNA formyltransferase, mitochondrial | chr15 | GO:0016741 | Not Cancer Driver | No | 35 | 0.09 | 56 | 3 | 0.054 | 3 |
| MTR | MTR | Q99707 | Methionine synthase | chr1 | GO:0016741 | Not Cancer Driver | No | 151 | 0.119 | 104 | 17 | 0.163 | 2 |
| N6AMT1 | N6AMT1 | Q9Y5N5 | Methyltransferase N6AMT1 | chr21 | GO:0016741 | Not Cancer Driver | No | 44 | 0.206 | 20 | 3 | 0.15 | 0 |
| NDUFAF7 | NDUFAF7 | Q7L592 | Protein arginine methyltransferase NDUFAF7, mitochondrial | chr2 | GO:0016741 | Not Cancer Driver | No | 53 | 0.12 | 19 | 3 | 0.158 | 0 |
| NNMT | NNMT | P40261 | Nicotinamide N-methyltransferase | chr11 | GO:0016741 | Not Cancer Driver | No | 51 | 0.193 | 5 | 1 | 0.2 | 0 |
| NOP2_ENST00000322166 | NOP2 | P46087 | Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase | chr12 | GO:0016741 | Not Cancer Driver | No | 116 | 0.143 | 510 | 72 | 0.141 | 0 |
| NSD1 | NSD1 | Q96L73 | Histone-lysine N-methyltransferase, H3 lysine-36 specific | chr5 | GO:0016741 | Census, Compendium | Yes | 343 | 0.127 | 1864 | 206 | 0.111 | 14 |
| NSD2_ENST00000382892 | NSD2 | O96028 | Histone-lysine N-methyltransferase NSD2 | chr4 | GO:0016741 | Census, Compendium | Yes | 191 | 0.14 | 552 | 76 | 0.138 | 0 |
| NSD3 | NSD3 | Q9BZ95 | Histone-lysine N-methyltransferase NSD3 | chr8 | GO:0016741 | Census | Yes | 164 | 0.114 | 679 | 98 | 0.144 | 0 |
| NSUN2 | NSUN2 | Q08J23 | RNA cytosine C(5)-methyltransferase NSUN2 | chr5 | GO:0016741 | Not Cancer Driver | No | 112 | 0.146 | 221 | 21 | 0.095 | 1 |
| NSUN3 | NSUN3 | Q9H649 | tRNA (cytosine(34)-C(5))-methyltransferase, mitochondrial | chr3 | GO:0016741 | Not Cancer Driver | No | 34 | 0.1 | 0 | 0 | 0.0 | 0 |
| NSUN4 | NSUN4 | Q96CB9 | 5-methylcytosine rRNA methyltransferase NSUN4 | chr1 | GO:0016741 | Not Cancer Driver | No | 40 | 0.104 | 20 | 5 | 0.25 | 0 |
| NSUN5_ENST00000252594 | NSUN5 | Q96P11 | 28S rRNA (cytosine-C(5))-methyltransferase | chr7 | GO:0016741 | Not Cancer Driver | No | 52 | 0.121 | 47 | 7 | 0.149 | 0 |
| NSUN6 | NSUN6 | Q8TEA1 | tRNA (cytosine(72)-C(5))-methyltransferase NSUN6 | chr10 | GO:0016741 | Not Cancer Driver | No | 68 | 0.145 | 50 | 10 | 0.2 | 0 |
| NTMT1_ENST00000613644 | NTMT1 | Q9BV86 | N-terminal Xaa-Pro-Lys N-methyltransferase 1 | chr9 | GO:0016741 | Not Cancer Driver | No | 27 | 0.121 | 1 | 0 | 0.0 | 0 |
| OTC | OTC | P00480 | Ornithine transcarbamylase, mitochondrial | chrX | GO:0016741 | Not Cancer Driver | No | 89 | 0.251 | 24 | 4 | 0.167 | 111 |
| PCIF1 | PCIF1 | Q9H4Z3 | mRNA (2'-O-methyladenosine-N(6)-)-methyltransferase | chr20 | GO:0016741 | Not Cancer Driver | No | 77 | 0.109 | 288 | 37 | 0.128 | 0 |
| PCMTD1_ENST00000522514 | PCMTD1 | Q96MG8 | Protein-L-isoaspartate O-methyltransferase domain-containing protein 1 | chr8 | GO:0016741 | Compendium | Yes | 90 | 0.252 | 101 | 45 | 0.446 | 0 |
| PCMTD2 | PCMTD2 | Q9NV79 | Protein-L-isoaspartate O-methyltransferase domain-containing protein 2 | chr20 | GO:0016741 | Not Cancer Driver | No | 55 | 0.152 | 75 | 17 | 0.227 | 0 |
| PEMT_ENST00000395783 | PEMT | Q9UBM1 | Phosphatidylethanolamine N-methyltransferase | chr17 | GO:0016741 | Not Cancer Driver | No | 21 | 0.106 | 1 | 0 | 0.0 | 0 |
| PNMT | PNMT | P11086 | Phenylethanolamine N-methyltransferase | chr17 | GO:0016741 | Not Cancer Driver | No | 36 | 0.128 | 44 | 4 | 0.091 | 0 |
| PRDM16 | PRDM16 | Q9HAZ2 | Histone-lysine N-methyltransferase PRDM16 | chr1 | GO:0016741 | Census | Yes | 254 | 0.199 | 830 | 152 | 0.183 | 1 |
| PRDM7_ENST00000449207 | PRDM7 | Q9NQW5 | Histone-lysine N-methyltransferase PRDM7 | chr16 | GO:0016741 | Not Cancer Driver | No | 62 | 0.126 | 280 | 26 | 0.093 | 0 |
| PRDM9 | PRDM9 | Q9NQV7 | Histone-lysine N-methyltransferase PRDM9 | chr5 | GO:0016741 | Not Cancer Driver | No | 494 | 0.553 | 372 | 201 | 0.54 | 0 |
| PRMT1 | PRMT1 | Q99873 | Protein arginine N-methyltransferase 1 | chr19 | GO:0016741 | Not Cancer Driver | No | 50 | 0.135 | 18 | 1 | 0.056 | 0 |
| PRMT2_ENST00000355680 | PRMT2 | P55345 | Protein arginine N-methyltransferase 2 | chr21 | GO:0016741 | Not Cancer Driver | No | 48 | 0.111 | 70 | 8 | 0.114 | 0 |
| PRMT3 | PRMT3 | O60678 | Protein arginine N-methyltransferase 3 | chr11 | GO:0016741 | Not Cancer Driver | No | 68 | 0.128 | 52 | 9 | 0.173 | 0 |
| PRMT5 | PRMT5 | O14744 | Protein arginine N-methyltransferase 5 | chr14 | GO:0016741 | Not Cancer Driver | No | 83 | 0.13 | 72 | 6 | 0.083 | 0 |
| PRMT6 | PRMT6 | Q96LA8 | Protein arginine N-methyltransferase 6 | chr1 | GO:0016741 | Not Cancer Driver | No | 43 | 0.115 | 71 | 7 | 0.099 | 0 |
| PRMT7_ENST00000441236 | PRMT7 | Q9NVM4 | Protein arginine N-methyltransferase 7 | chr16 | GO:0016741 | Not Cancer Driver | No | 71 | 0.103 | 39 | 1 | 0.026 | 3 |
| PRMT8 | PRMT8 | Q9NR22 | Protein arginine N-methyltransferase 8 | chr12 | GO:0016741 | Not Cancer Driver | No | 94 | 0.239 | 61 | 16 | 0.262 | 0 |
| PRMT9 | PRMT9 | Q6P2P2 | Protein arginine N-methyltransferase 9 | chr4 | GO:0016741 | Not Cancer Driver | No | 84 | 0.099 | 63 | 4 | 0.063 | 0 |
| RBBP5 | RBBP5 | Q15291 | Retinoblastoma-binding protein 5 | chr1 | GO:0016741 | Not Cancer Driver | No | 57 | 0.106 | 218 | 19 | 0.087 | 0 |
| RNMT_ENST00000543302 | RNMT | O43148 | mRNA cap guanine-N7 methyltransferase | chr18 | GO:0016741 | Not Cancer Driver | No | 67 | 0.141 | 159 | 23 | 0.145 | 0 |
| RRNAD1 | METTL25B | Q96FB5 | Methyltransferase-like protein 25B | chr1 | GO:0016741 | Not Cancer Driver | No | 56 | 0.118 | 59 | 5 | 0.085 | 0 |
| SETD1A | SETD1A | O15047 | Histone-lysine N-methyltransferase SETD1A | chr16 | GO:0016741 | Not Cancer Driver | No | 223 | 0.131 | 1327 | 188 | 0.142 | 5 |
| SETD1B | SETD1B | Q9UPS6 | Histone-lysine N-methyltransferase SETD1B | chr12 | GO:0016741 | Census, Compendium | Yes | 88 | 0.045 | 1479 | 61 | 0.041 | 4 |
| SETD2 | SETD2 | Q9BYW2 | Histone-lysine N-methyltransferase SETD2 | chr3 | GO:0016741 | Census, Compendium | Yes | 321 | 0.125 | 1945 | 209 | 0.107 | 2 |
| SETD3 | SETD3 | Q86TU7 | Actin-histidine N-methyltransferase | chr14 | GO:0016741 | Not Cancer Driver | No | 73 | 0.123 | 140 | 24 | 0.171 | 0 |
| SETD4 | SETD4 | Q9NVD3 | SET domain-containing protein 4 | chr21 | GO:0016741 | Not Cancer Driver | No | 51 | 0.116 | 27 | 2 | 0.074 | 0 |
| SETD5 | SETD5 | Q9C0A6 | Histone-lysine N-methyltransferase SETD5 | chr3 | GO:0016741 | Not Cancer Driver | No | 208 | 0.144 | 1130 | 165 | 0.146 | 1 |
| SETDB1 | SETDB1 | Q15047 | Histone-lysine N-methyltransferase SETDB1 | chr1 | GO:0016741 | Census, Compendium | Yes | 184 | 0.143 | 597 | 77 | 0.129 | 0 |
| SETDB2 | SETDB2 | Q96T68 | Histone-lysine N-methyltransferase SETDB2 | chr13 | GO:0016741 | Not Cancer Driver | No | 70 | 0.097 | 253 | 26 | 0.103 | 0 |
| SETMAR | SETMAR | Q53H47 | Histone-lysine N-methyltransferase SETMAR | chr3 | GO:0016741 | Not Cancer Driver | No | 62 | 0.091 | 154 | 12 | 0.078 | 0 |
| SHMT1 | SHMT1 | P34896 | Serine hydroxymethyltransferase, cytosolic | chr17 | GO:0016741 | Not Cancer Driver | No | 51 | 0.106 | 32 | 7 | 0.219 | 0 |
| SHMT2 | SHMT2 | P34897 | Serine hydroxymethyltransferase, mitochondrial | chr12 | GO:0016741 | Not Cancer Driver | No | 57 | 0.113 | 58 | 5 | 0.086 | 1 |
| SMYD2 | SMYD2 | Q9NRG4 | N-lysine methyltransferase SMYD2 | chr1 | GO:0016741 | Not Cancer Driver | No | 42 | 0.097 | 12 | 0 | 0.0 | 0 |
| SMYD5 | SMYD5 | Q6GMV2 | Histone-lysine N-trimethyltransferase SMYD5 | chr2 | GO:0016741 | Not Cancer Driver | No | 60 | 0.144 | 50 | 6 | 0.12 | 0 |
| SUV39H1_ENST00000376687 | SUV39H1 | O43463 | Histone-lysine N-methyltransferase SUV39H1 | chrX | GO:0016741 | Not Cancer Driver | No | 59 | 0.143 | 15 | 1 | 0.067 | 0 |
| SUV39H2 | SUV39H2 | Q9H5I1 | Histone-lysine N-methyltransferase SUV39H2 | chr10 | GO:0016741 | Not Cancer Driver | No | 39 | 0.095 | 23 | 1 | 0.043 | 0 |
| TARBP1 | TARBP1 | Q13395 | Probable methyltransferase TARBP1 | chr1 | GO:0016741 | Not Cancer Driver | No | 165 | 0.102 | 90 | 4 | 0.044 | 0 |
| TFB1M | TFB1M | Q8WVM0 | Dimethyladenosine transferase 1, mitochondrial | chr6 | GO:0016741 | Not Cancer Driver | No | 50 | 0.145 | 26 | 3 | 0.115 | 0 |
| TFB2M | TFB2M | Q9H5Q4 | Dimethyladenosine transferase 2, mitochondrial | chr1 | GO:0016741 | Not Cancer Driver | No | 60 | 0.152 | 36 | 6 | 0.167 | 0 |
| TGS1 | TGS1 | Q96RS0 | Trimethylguanosine synthase | chr8 | GO:0016741 | Not Cancer Driver | No | 100 | 0.117 | 483 | 56 | 0.116 | 0 |
| THUMPD2 | THUMPD2 | Q9BTF0 | THUMP domain-containing protein 2 | chr2 | GO:0016741 | Not Cancer Driver | No | 38 | 0.076 | 92 | 7 | 0.076 | 0 |
| THUMPD3 | THUMPD3 | Q9BV44 | tRNA (guanine(6)-N2)-methyltransferase THUMP3 | chr3 | GO:0016741 | Not Cancer Driver | No | 48 | 0.095 | 73 | 3 | 0.041 | 0 |
| TPMT | TPMT | P51580 | Thiopurine S-methyltransferase | chr6 | GO:0016741 | Not Cancer Driver | No | 23 | 0.094 | 13 | 1 | 0.077 | 0 |
| TRDMT1 | TRDMT1 | O14717 | tRNA (cytosine(38)-C(5))-methyltransferase | chr10 | GO:0016741 | Not Cancer Driver | No | 65 | 0.166 | 19 | 3 | 0.158 | 0 |
| TRMO | TRMO | Q9BU70 | tRNA (adenine(37)-N6)-methyltransferase | chr9 | GO:0016741 | Not Cancer Driver | No | 57 | 0.129 | 228 | 25 | 0.11 | 0 |
| TRMT10A_ENST00000394876 | TRMT10A | Q8TBZ6 | tRNA methyltransferase 10 homolog A | chr4 | GO:0016741 | Not Cancer Driver | No | 49 | 0.145 | 182 | 28 | 0.154 | 1 |
| TRMT10B | TRMT10B | Q6PF06 | tRNA methyltransferase 10 homolog B | chr9 | GO:0016741 | Not Cancer Driver | No | 35 | 0.111 | 75 | 13 | 0.173 | 0 |
| TRMT10C | TRMT10C | Q7L0Y3 | tRNA methyltransferase 10 homolog C | chr3 | GO:0016741 | Not Cancer Driver | No | 56 | 0.139 | 59 | 10 | 0.169 | 2 |
| TRMT11 | TRMT11 | Q7Z4G4 | tRNA (guanine(10)-N2)-methyltransferase homolog | chr6 | GO:0016741 | Not Cancer Driver | No | 38 | 0.082 | 45 | 3 | 0.067 | 0 |
| TRMT13 | TRMT13 | Q9NUP7 | tRNA:m(4)X modification enzyme TRM13 homolog | chr1 | GO:0016741 | Not Cancer Driver | No | 69 | 0.143 | 177 | 31 | 0.175 | 0 |
| TRMT1L | TRMT1L | Q7Z2T5 | TRMT1-like protein | chr1 | GO:0016741 | Not Cancer Driver | No | 71 | 0.097 | 241 | 19 | 0.079 | 0 |
| TRMT1_ENST00000357720 | TRMT1 | Q9NXH9 | tRNA (guanine(26)-N(2))-dimethyltransferase | chr19 | GO:0016741 | Not Cancer Driver | No | 82 | 0.124 | 200 | 24 | 0.12 | 0 |
| TRMT2B_ENST00000545398 | TRMT2B | Q96GJ1 | tRNA (uracil-5-)-methyltransferase homolog B | chrX | GO:0016741 | Not Cancer Driver | No | 75 | 0.149 | 31 | 2 | 0.065 | 0 |
| TRMT44 | TRMT44 | Q8IYL2 | Probable tRNA (uracil-O(2)-)-methyltransferase | chr4 | GO:0016741 | Not Cancer Driver | No | 57 | 0.075 | 260 | 16 | 0.062 | 0 |
| TRMT5 | TRMT5 | Q32P41 | tRNA (guanine(37)-N1)-methyltransferase | chr14 | GO:0016741 | Not Cancer Driver | No | 46 | 0.09 | 67 | 5 | 0.075 | 2 |
| TRMT61A | TRMT61A | Q96FX7 | tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A | chr14 | GO:0016741 | Not Cancer Driver | No | 16 | 0.055 | 74 | 9 | 0.122 | 0 |
| TRMT61B | TRMT61B | Q9BVS5 | tRNA (adenine(58)-N(1))-methyltransferase, mitochondrial | chr2 | GO:0016741 | Not Cancer Driver | No | 48 | 0.101 | 123 | 10 | 0.081 | 0 |
| TRMT9B | TRMT9B | Q9P272 | Probable tRNA methyltransferase 9B | chr8 | GO:0016741 | Not Cancer Driver | No | 73 | 0.161 | 151 | 16 | 0.106 | 0 |
| TYMS | TYMS | P04818 | Thymidylate synthase | chr18 | GO:0016741 | Not Cancer Driver | No | 22 | 0.07 | 41 | 0 | 0.0 | 0 |
| WDR4 | WDR4 | P57081 | tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4 | chr21 | GO:0016741 | Not Cancer Driver | No | 37 | 0.09 | 49 | 4 | 0.082 | 2 |
| WDR5 | WDR5 | P61964 | WD repeat-containing protein 5 | chr9 | GO:0016741 | Not Cancer Driver | No | 30 | 0.09 | 35 | 3 | 0.086 | 0 |
| WDR82 | WDR82 | Q6UXN9 | WD repeat-containing protein 82 | chr3 | GO:0016741 | Not Cancer Driver | No | 35 | 0.112 | 0 | 0 | 0.0 | 0 |
| ZCCHC4 | ZCCHC4 | Q9H5U6 | rRNA N6-adenosine-methyltransferase ZCCHC4 | chr4 | GO:0016741 | Not Cancer Driver | No | 57 | 0.111 | 69 | 4 | 0.058 | 0 |