Total number of protein in "GO:0016627" GO term: 56
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACAA1 | ACAA1 | P09110 | 3-ketoacyl-CoA thiolase, peroxisomal | chr3 | GO:0016627 | Not Cancer Driver | No | 37 | 0.087 | 116 | 8 | 0.069 | 0 |
| ACAD11 | ACAD11 | Q709F0 | Acyl-CoA dehydrogenase family member 11 | chr3 | GO:0016627 | Not Cancer Driver | No | 108 | 0.138 | 33 | 4 | 0.121 | 0 |
| ACAD9 | ACAD9 | Q9H845 | Complex I assembly factor ACAD9, mitochondrial | chr3 | GO:0016627 | Not Cancer Driver | No | 69 | 0.111 | 28 | 5 | 0.179 | 12 |
| ACADL | ACADL | P28330 | Long-chain specific acyl-CoA dehydrogenase, mitochondrial | chr2 | GO:0016627 | Not Cancer Driver | No | 63 | 0.147 | 51 | 3 | 0.059 | 0 |
| ACADM_ENST00000370841 | ACADM | P11310 | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | chr1 | GO:0016627 | Not Cancer Driver | No | 61 | 0.145 | 41 | 5 | 0.122 | 19 |
| ACADS | ACADS | P16219 | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | chr12 | GO:0016627 | Not Cancer Driver | No | 53 | 0.129 | 16 | 3 | 0.188 | 10 |
| ACADSB | ACADSB | P45954 | Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial | chr10 | GO:0016627 | Not Cancer Driver | No | 59 | 0.137 | 16 | 3 | 0.188 | 1 |
| ACADVL_ENST00000356839 | ACADVL | P49748 | Very long-chain specific acyl-CoA dehydrogenase, mitochondrial | chr17 | GO:0016627 | Not Cancer Driver | No | 50 | 0.076 | 100 | 5 | 0.05 | 37 |
| ACOX1_ENST00000301608 | ACOX1 | Q15067 | Peroxisomal acyl-coenzyme A oxidase 1 | chr17 | GO:0016627 | Not Cancer Driver | No | 71 | 0.108 | 63 | 11 | 0.175 | 7 |
| ACOX2 | ACOX2 | Q99424 | Peroxisomal acyl-coenzyme A oxidase 2 | chr3 | GO:0016627 | Not Cancer Driver | No | 79 | 0.116 | 35 | 9 | 0.257 | 1 |
| ACOX3 | ACOX3 | O15254 | Peroxisomal acyl-coenzyme A oxidase 3 | chr4 | GO:0016627 | Not Cancer Driver | No | 107 | 0.153 | 26 | 6 | 0.231 | 0 |
| ACOXL_ENST00000389811 | ACOXL | Q9NUZ1 | Acyl-coenzyme A oxidase-like protein | chr2 | GO:0016627 | Not Cancer Driver | No | 96 | 0.176 | 21 | 4 | 0.19 | 0 |
| AKR1C1 | AKR1C1 | Q04828 | Aldo-keto reductase family 1 member C1 | chr10 | GO:0016627 | Not Cancer Driver | No | 56 | 0.173 | 1 | 0 | 0.0 | 0 |
| AKR1C2 | AKR1C2 | P52895 | Aldo-keto reductase family 1 member C2 | chr10 | GO:0016627 | Not Cancer Driver | No | 32 | 0.099 | 1 | 0 | 0.0 | 4 |
| AKR1C3 | AKR1C3 | P42330 | Aldo-keto reductase family 1 member C3 | chr10 | GO:0016627 | Not Cancer Driver | No | 49 | 0.152 | 11 | 1 | 0.091 | 0 |
| AKR1D1 | AKR1D1 | P51857 | Aldo-keto reductase family 1 member D1 | chr7 | GO:0016627 | Not Cancer Driver | No | 89 | 0.273 | 15 | 3 | 0.2 | 5 |
| BLVRA | BLVRA | P53004 | Biliverdin reductase A | chr7 | GO:0016627 | Not Cancer Driver | No | 34 | 0.115 | 6 | 1 | 0.167 | 0 |
| BLVRB | BLVRB | P30043 | Flavin reductase (NADPH) | chr19 | GO:0016627 | Not Cancer Driver | No | 16 | 0.078 | 56 | 6 | 0.107 | 0 |
| COX15 | COX15 | Q7KZN9 | Cytochrome c oxidase assembly protein COX15 homolog | chr10 | GO:0016627 | Not Cancer Driver | No | 48 | 0.117 | 0 | 0 | 0.0 | 2 |
| CPOX | CPOX | P36551 | Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial | chr3 | GO:0016627 | Not Cancer Driver | No | 49 | 0.108 | 126 | 7 | 0.056 | 17 |
| CRAT | CRAT | P43155 | Carnitine O-acetyltransferase | chr9 | GO:0016627 | Not Cancer Driver | No | 74 | 0.118 | 27 | 4 | 0.148 | 0 |
| CYP2S1 | CYP2S1 | Q96SQ9 | Cytochrome P450 2S1 | chr19 | GO:0016627 | Not Cancer Driver | No | 75 | 0.149 | 46 | 10 | 0.217 | 0 |
| DECR1 | DECR1 | Q16698 | 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial | chr8 | GO:0016627 | Not Cancer Driver | No | 38 | 0.113 | 11 | 0 | 0.0 | 0 |
| DECR2 | DECR2 | Q9NUI1 | Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing] | chr16 | GO:0016627 | Not Cancer Driver | No | 44 | 0.151 | 36 | 2 | 0.056 | 0 |
| DHCR24 | DHCR24 | Q15392 | Delta(24)-sterol reductase | chr1 | GO:0016627 | Not Cancer Driver | No | 55 | 0.107 | 0 | 0 | 0.0 | 6 |
| DHCR7 | DHCR7 | Q9UBM7 | 7-dehydrocholesterol reductase | chr11 | GO:0016627 | Not Cancer Driver | No | 85 | 0.179 | 7 | 1 | 0.143 | 53 |
| DHDH | DHDH | Q9UQ10 | Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase | chr19 | GO:0016627 | Not Cancer Driver | No | 54 | 0.162 | 18 | 2 | 0.111 | 0 |
| DHODH | DHODH | Q02127 | Dihydroorotate dehydrogenase (quinone), mitochondrial | chr16 | GO:0016627 | Not Cancer Driver | No | 44 | 0.111 | 96 | 11 | 0.115 | 10 |
| DPYD | DPYD | Q12882 | Dihydropyrimidine dehydrogenase [NADP(+)] | chr1 | GO:0016627 | Not Cancer Driver | No | 303 | 0.296 | 77 | 23 | 0.299 | 3 |
| DUS1L_ENST00000306796 | DUS1L | Q6P1R4 | tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]-like | chr17 | GO:0016627 | Not Cancer Driver | No | 52 | 0.11 | 110 | 10 | 0.091 | 0 |
| DUS2 | DUS2 | Q9NX74 | tRNA-dihydrouridine(20) synthase [NAD(P)+]-like | chr16 | GO:0016627 | Not Cancer Driver | No | 48 | 0.097 | 117 | 10 | 0.085 | 0 |
| DUS3L | DUS3L | Q96G46 | tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like | chr19 | GO:0016627 | Not Cancer Driver | No | 82 | 0.126 | 234 | 27 | 0.115 | 0 |
| DUS4L | DUS4L | O95620 | tRNA-dihydrouridine(20a/20b) synthase [NAD(P)+]-like | chr7 | GO:0016627 | Not Cancer Driver | No | 38 | 0.12 | 3 | 0 | 0.0 | 0 |
| FASN | FASN | P49327 | Fatty acid synthase | chr17 | GO:0016627 | Not Cancer Driver | No | 291 | 0.116 | 309 | 42 | 0.136 | 0 |
| GCDH_ENST00000591470 | GCDH | Q92947 | Glutaryl-CoA dehydrogenase, mitochondrial | chr19 | GO:0016627 | Not Cancer Driver | No | 57 | 0.13 | 37 | 5 | 0.135 | 58 |
| IVD | IVD | P26440 | Isovaleryl-CoA dehydrogenase, mitochondrial | chr15 | GO:0016627 | Not Cancer Driver | No | 46 | 0.108 | 8 | 0 | 0.0 | 14 |
| LBR_ENST00000272163 | LBR | Q14739 | Delta(14)-sterol reductase LBR | chr1 | GO:0016627 | Not Cancer Driver | No | 95 | 0.154 | 130 | 15 | 0.115 | 5 |
| MECR | MECR | Q9BV79 | Enoyl-[acyl-carrier-protein] reductase, mitochondrial | chr1 | GO:0016627 | Not Cancer Driver | No | 55 | 0.147 | 26 | 5 | 0.192 | 3 |
| PECR | PECR | Q9BY49 | Peroxisomal trans-2-enoyl-CoA reductase | chr2 | GO:0016627 | Not Cancer Driver | No | 29 | 0.096 | 8 | 0 | 0.0 | 0 |
| PPOX | PPOX | P50336 | Protoporphyrinogen oxidase | chr1 | GO:0016627 | Not Cancer Driver | No | 48 | 0.101 | 34 | 6 | 0.176 | 56 |
| PTGES2 | PTGES2 | Q9H7Z7 | Prostaglandin E synthase 2 | chr9 | GO:0016627 | Not Cancer Driver | No | 30 | 0.08 | 30 | 1 | 0.033 | 0 |
| PTGR1_ENST00000309195 | PTGR1 | Q14914 | Prostaglandin reductase 1 | chr9 | GO:0016627 | Not Cancer Driver | No | 40 | 0.122 | 12 | 1 | 0.083 | 0 |
| PTGR2 | PTGR2 | Q8N8N7 | Prostaglandin reductase 2 | chr14 | GO:0016627 | Not Cancer Driver | No | 26 | 0.074 | 22 | 2 | 0.091 | 0 |
| RETSAT | RETSAT | Q6NUM9 | All-trans-retinol 13,14-reductase | chr2 | GO:0016627 | Not Cancer Driver | No | 98 | 0.161 | 25 | 5 | 0.2 | 0 |
| RSAD1 | RSAD1 | Q9HA92 | Radical S-adenosyl methionine domain-containing protein 1, mitochondrial | chr17 | GO:0016627 | Not Cancer Driver | No | 68 | 0.154 | 88 | 13 | 0.148 | 0 |
| SDHA | SDHA | P31040 | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | chr5 | GO:0016627 | Census | Yes | 115 | 0.173 | 71 | 13 | 0.183 | 7 |
| SDHB | SDHB | P21912 | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | chr1 | GO:0016627 | Census | Yes | 37 | 0.132 | 17 | 3 | 0.176 | 23 |
| SDHC | SDHC | Q99643 | Succinate dehydrogenase cytochrome b560 subunit, mitochondrial | chr1 | GO:0016627 | Census | Yes | 16 | 0.095 | 0 | 0 | 0.0 | 0 |
| SRD5A1 | SRD5A1 | P18405 | 3-oxo-5-alpha-steroid 4-dehydrogenase 1 | chr5 | GO:0016627 | Not Cancer Driver | No | 35 | 0.135 | 0 | 0 | 0.0 | 0 |
| SRD5A2 | SRD5A2 | P31213 | 3-oxo-5-alpha-steroid 4-dehydrogenase 2 | chr2 | GO:0016627 | Not Cancer Driver | No | 48 | 0.189 | 0 | 0 | 0.0 | 21 |
| SRD5A3 | SRD5A3 | Q9H8P0 | Polyprenol reductase | chr4 | GO:0016627 | Not Cancer Driver | No | 35 | 0.11 | 0 | 0 | 0.0 | 0 |
| TBXAS1_ENST00000448866 | TBXAS1 | P24557 | Thromboxane-A synthase | chr7 | GO:0016627 | Not Cancer Driver | No | 116 | 0.218 | 44 | 8 | 0.182 | 4 |
| TECR | TECR | Q9NZ01 | Very-long-chain enoyl-CoA reductase | chr19 | GO:0016627 | Not Cancer Driver | No | 41 | 0.133 | 0 | 0 | 0.0 | 1 |
| TECRL | TECRL | Q5HYJ1 | Trans-2,3-enoyl-CoA reductase-like | chr4 | GO:0016627 | Not Cancer Driver | No | 147 | 0.405 | 6 | 4 | 0.667 | 0 |
| TM7SF2 | TM7SF2 | O76062 | Delta(14)-sterol reductase TM7SF2 | chr11 | GO:0016627 | Not Cancer Driver | No | 51 | 0.122 | 15 | 1 | 0.067 | 0 |
| ZADH2 | PTGR3 | Q8N4Q0 | Prostaglandin reductase 3 | chr18 | GO:0016627 | Not Cancer Driver | No | 42 | 0.111 | 0 | 0 | 0.0 | 0 |