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Total number of protein in "GO:0016491" GO term:  666

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
AASS AASS Q9UDR5 Alpha-aminoadipic semialdehyde synthase, mitochondrial chr7 GO:0016491 Not Cancer Driver No 161 0.174 18 3 0.167 0
ABCC4_ENST00000376887 ABCC4 O15439 ATP-binding cassette sub-family C member 4 chr13 GO:0016491 Not Cancer Driver No 174 0.131 97 6 0.062 0
AC090527.2 AC090527.2 H3BNX3 Pyr_redox_2 domain-containing protein (Fragment) chr15 GO:0016491 Not Cancer Driver No 36 0.125 22 4 0.182 0
AC135050.2 AC135050.2 E9PLN8 VKc domain-containing protein (Fragment) chr16 GO:0016491 Not Cancer Driver No 12 0.072 23 2 0.087 0
ACAA1 ACAA1 P09110 3-ketoacyl-CoA thiolase, peroxisomal chr3 GO:0016491 Not Cancer Driver No 37 0.087 116 8 0.069 0
ACAD11 ACAD11 Q709F0 Acyl-CoA dehydrogenase family member 11 chr3 GO:0016491 Not Cancer Driver No 108 0.138 33 4 0.121 0
ACAD9 ACAD9 Q9H845 Complex I assembly factor ACAD9, mitochondrial chr3 GO:0016491 Not Cancer Driver No 69 0.111 28 5 0.179 12
ACADL ACADL P28330 Long-chain specific acyl-CoA dehydrogenase, mitochondrial chr2 GO:0016491 Not Cancer Driver No 63 0.147 51 3 0.059 0
ACADM_ENST00000370841 ACADM P11310 Medium-chain specific acyl-CoA dehydrogenase, mitochondrial chr1 GO:0016491 Not Cancer Driver No 61 0.145 41 5 0.122 19
ACADS ACADS P16219 Short-chain specific acyl-CoA dehydrogenase, mitochondrial chr12 GO:0016491 Not Cancer Driver No 53 0.129 16 3 0.188 10
ACADSB ACADSB P45954 Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial chr10 GO:0016491 Not Cancer Driver No 59 0.137 16 3 0.188 1
ACADVL_ENST00000356839 ACADVL P49748 Very long-chain specific acyl-CoA dehydrogenase, mitochondrial chr17 GO:0016491 Not Cancer Driver No 50 0.076 100 5 0.05 37
ACOX1_ENST00000301608 ACOX1 Q15067 Peroxisomal acyl-coenzyme A oxidase 1 chr17 GO:0016491 Not Cancer Driver No 71 0.108 63 11 0.175 7
ACOX2 ACOX2 Q99424 Peroxisomal acyl-coenzyme A oxidase 2 chr3 GO:0016491 Not Cancer Driver No 79 0.116 35 9 0.257 1
ACOX3 ACOX3 O15254 Peroxisomal acyl-coenzyme A oxidase 3 chr4 GO:0016491 Not Cancer Driver No 107 0.153 26 6 0.231 0
ACOXL_ENST00000389811 ACOXL Q9NUZ1 Acyl-coenzyme A oxidase-like protein chr2 GO:0016491 Not Cancer Driver No 96 0.176 21 4 0.19 0
ADH1A ADH1A P07327 Alcohol dehydrogenase 1A chr4 GO:0016491 Not Cancer Driver No 73 0.195 6 3 0.5 0
ADH1B ADH1B P00325 All-trans-retinol dehydrogenase [NAD(+)] ADH1B chr4 GO:0016491 Not Cancer Driver No 108 0.288 6 4 0.667 0
ADH1C ADH1C P00326 Alcohol dehydrogenase 1C chr4 GO:0016491 Not Cancer Driver No 116 0.309 6 5 0.833 0
ADH4_ENST00000265512 ADH4 P08319 All-trans-retinol dehydrogenase [NAD(+)] ADH4 chr4 GO:0016491 Not Cancer Driver No 49 0.129 5 1 0.2 0
ADH5 ADH5 P11766 Alcohol dehydrogenase class-3 chr4 GO:0016491 Not Cancer Driver No 36 0.096 2 1 0.5 0
ADH6_ENST00000237653 ADH6 P28332 Alcohol dehydrogenase 6 chr4 GO:0016491 Not Cancer Driver No 71 0.193 0 0 0.0 0
ADH7_ENST00000209665 ADH7 P40394 All-trans-retinol dehydrogenase [NAD(+)] ADH7 chr4 GO:0016491 Not Cancer Driver No 74 0.192 15 2 0.133 0
ADHFE1 ADHFE1 Q8IWW8 Hydroxyacid-oxoacid transhydrogenase, mitochondrial chr8 GO:0016491 Not Cancer Driver No 63 0.135 37 8 0.216 0
ADI1 ADI1 Q9BV57 Acireductone dioxygenase chr2 GO:0016491 Not Cancer Driver No 27 0.151 23 1 0.043 0
ADO ADO Q96SZ5 2-aminoethanethiol dioxygenase chr10 GO:0016491 Not Cancer Driver No 18 0.067 178 12 0.067 0
AGMO AGMO Q6ZNB7 Alkylglycerol monooxygenase chr7 GO:0016491 Not Cancer Driver No 134 0.301 7 2 0.286 0
AGPS AGPS O00116 Alkyldihydroxyacetonephosphate synthase, peroxisomal chr2 GO:0016491 Not Cancer Driver No 68 0.103 151 10 0.066 6
AIFM1 AIFM1 O95831 Apoptosis-inducing factor 1, mitochondrial chrX GO:0016491 Not Cancer Driver No 88 0.144 166 22 0.133 11
AIFM2_ENST00000307864 AIFM2 Q9BRQ8 Ferroptosis suppressor protein 1 chr10 GO:0016491 Not Cancer Driver No 47 0.126 8 0 0.0 0
AIFM3 AIFM3 Q96NN9 Apoptosis-inducing factor 3 chr22 GO:0016491 Not Cancer Driver No 87 0.144 66 15 0.227 0
AKR1A1_ENST00000621846 AKR1A1 P14550 Aldo-keto reductase family 1 member A1 chr1 GO:0016491 Not Cancer Driver No 40 0.123 26 4 0.154 0
AKR1B1 AKR1B1 P15121 Aldo-keto reductase family 1 member B1 chr7 GO:0016491 Not Cancer Driver No 52 0.165 19 1 0.053 0
AKR1B10 AKR1B10 O60218 Aldo-keto reductase family 1 member B10 chr7 GO:0016491 Not Cancer Driver No 58 0.184 28 4 0.143 0
AKR1C1 AKR1C1 Q04828 Aldo-keto reductase family 1 member C1 chr10 GO:0016491 Not Cancer Driver No 56 0.173 1 0 0.0 0
AKR1C2 AKR1C2 P52895 Aldo-keto reductase family 1 member C2 chr10 GO:0016491 Not Cancer Driver No 32 0.099 1 0 0.0 4
AKR1C3 AKR1C3 P42330 Aldo-keto reductase family 1 member C3 chr10 GO:0016491 Not Cancer Driver No 49 0.152 11 1 0.091 0
AKR1C4 AKR1C4 P17516 Aldo-keto reductase family 1 member C4 chr10 GO:0016491 Not Cancer Driver No 78 0.241 9 3 0.333 0
AKR1D1 AKR1D1 P51857 Aldo-keto reductase family 1 member D1 chr7 GO:0016491 Not Cancer Driver No 89 0.273 15 3 0.2 5
AKR1E2 AKR1E2 Q96JD6 1,5-anhydro-D-fructose reductase chr10 GO:0016491 Not Cancer Driver No 46 0.144 0 0 0.0 0
AKR7A2 AKR7A2 O43488 Aflatoxin B1 aldehyde reductase member 2 chr1 GO:0016491 Not Cancer Driver No 35 0.097 90 3 0.033 0
AKR7A3 AKR7A3 O95154 Aflatoxin B1 aldehyde reductase member 3 chr1 GO:0016491 Not Cancer Driver No 44 0.133 47 2 0.043 0
AKR7L AKR7L Q8NHP1 Aflatoxin B1 aldehyde reductase member 4 chr1 GO:0016491 Not Cancer Driver No 40 0.121 50 4 0.08 0
ALDH16A1 ALDH16A1 Q8IZ83 Aldehyde dehydrogenase family 16 member A1 chr19 GO:0016491 Not Cancer Driver No 90 0.112 175 26 0.149 0
ALDH18A1 ALDH18A1 P54886 Delta-1-pyrroline-5-carboxylate synthase chr10 GO:0016491 Not Cancer Driver No 94 0.118 86 13 0.151 15
ALDH1A1 ALDH1A1 P00352 Aldehyde dehydrogenase 1A1 chr9 GO:0016491 Not Cancer Driver No 65 0.13 29 3 0.103 0
ALDH1A2 ALDH1A2 O94788 Retinal dehydrogenase 2 chr15 GO:0016491 Not Cancer Driver No 100 0.193 56 13 0.232 0
ALDH1A3 ALDH1A3 P47895 Aldehyde dehydrogenase family 1 member A3 chr15 GO:0016491 Not Cancer Driver No 74 0.145 73 7 0.096 10
ALDH1B1 ALDH1B1 P30837 Aldehyde dehydrogenase X, mitochondrial chr9 GO:0016491 Not Cancer Driver No 94 0.182 54 11 0.204 0
ALDH1L1_ENST00000393434 ALDH1L1 O75891 Cytosolic 10-formyltetrahydrofolate dehydrogenase chr3 GO:0016491 Not Cancer Driver No 159 0.176 87 19 0.218 0
ALDH1L2 ALDH1L2 Q3SY69 Mitochondrial 10-formyltetrahydrofolate dehydrogenase chr12 GO:0016491 Not Cancer Driver No 108 0.117 81 12 0.148 0
ALDH2 ALDH2 P05091 Aldehyde dehydrogenase, mitochondrial chr12 GO:0016491 Census Yes 60 0.116 44 1 0.023 0
ALDH3A1_ENST00000444455 ALDH3A1 P30838 Aldehyde dehydrogenase, dimeric NADP-preferring chr17 GO:0016491 Not Cancer Driver No 73 0.161 36 7 0.194 0
ALDH3A2_ENST00000579855 ALDH3A2 P51648 Aldehyde dehydrogenase family 3 member A2 chr17 GO:0016491 Not Cancer Driver No 47 0.097 5 2 0.4 26
ALDH3B1 ALDH3B1 P43353 Aldehyde dehydrogenase family 3 member B1 chr11 GO:0016491 Not Cancer Driver No 36 0.077 23 6 0.261 0
ALDH3B2 ALDH3B2 P48448 Aldehyde dehydrogenase family 3 member B2 chr11 GO:0016491 Not Cancer Driver No 71 0.184 17 4 0.235 0
ALDH4A1 ALDH4A1 P30038 Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial chr1 GO:0016491 Not Cancer Driver No 63 0.112 46 9 0.196 1
ALDH5A1_ENST00000357578 ALDH5A1 P51649 Succinate-semialdehyde dehydrogenase, mitochondrial chr6 GO:0016491 Not Cancer Driver No 64 0.12 31 7 0.226 12
ALDH6A1 ALDH6A1 Q02252 Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial chr14 GO:0016491 Not Cancer Driver No 54 0.101 83 11 0.133 1
ALDH7A1 ALDH7A1 P49419 Alpha-aminoadipic semialdehyde dehydrogenase chr5 GO:0016491 Not Cancer Driver No 52 0.096 26 1 0.038 8
ALDH8A1 ALDH8A1 Q9H2A2 2-aminomuconic semialdehyde dehydrogenase chr6 GO:0016491 Not Cancer Driver No 107 0.22 40 6 0.15 0
ALDH9A1 ALDH9A1 P49189 4-trimethylaminobutyraldehyde dehydrogenase chr1 GO:0016491 Not Cancer Driver No 57 0.115 16 0 0.0 0
ALKBH1 ALKBH1 Q13686 Nucleic acid dioxygenase ALKBH1 chr14 GO:0016491 Not Cancer Driver No 55 0.141 77 11 0.143 0
ALKBH2_ENST00000343075 ALKBH2 Q6NS38 DNA oxidative demethylase ALKBH2 chr12 GO:0016491 Not Cancer Driver No 34 0.13 73 14 0.192 0
ALKBH3 ALKBH3 Q96Q83 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 chr11 GO:0016491 Not Cancer Driver No 42 0.147 157 25 0.159 0
ALKBH4 ALKBH4 Q9NXW9 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4 chr7 GO:0016491 Not Cancer Driver No 39 0.129 14 2 0.143 0
ALKBH5 ALKBH5 Q6P6C2 RNA demethylase ALKBH5 chr17 GO:0016491 Not Cancer Driver No 41 0.104 200 23 0.115 0
ALOX12 ALOX12 P18054 Polyunsaturated fatty acid lipoxygenase ALOX12 chr17 GO:0016491 Not Cancer Driver No 73 0.11 73 12 0.164 0
ALOX12B ALOX12B O75342 Arachidonate 12-lipoxygenase, 12R-type chr17 GO:0016491 Not Cancer Driver No 101 0.144 16 3 0.188 18
ALOX15B ALOX15B O15296 Polyunsaturated fatty acid lipoxygenase ALOX15B chr17 GO:0016491 Not Cancer Driver No 99 0.146 62 12 0.194 0
ALOX15_ENST00000293761 ALOX15 P16050 Polyunsaturated fatty acid lipoxygenase ALOX15 chr17 GO:0016491 Not Cancer Driver No 84 0.127 46 7 0.152 0
ALOX5 ALOX5 P09917 Polyunsaturated fatty acid 5-lipoxygenase chr10 GO:0016491 Not Cancer Driver No 129 0.191 16 2 0.125 0
ALOX5AP_ENST00000380490 ALOX5AP P20292 Arachidonate 5-lipoxygenase-activating protein chr13 GO:0016491 Not Cancer Driver No 17 0.106 1 0 0.0 0
AOC1_ENST00000467291 AOC1 P19801 Amiloride-sensitive amine oxidase [copper-containing] chr7 GO:0016491 Not Cancer Driver No 161 0.214 98 26 0.265 0
AOC2 AOC2 O75106 Retina-specific copper amine oxidase chr17 GO:0016491 Not Cancer Driver No 116 0.153 112 12 0.107 0
AOC3 AOC3 Q16853 Membrane primary amine oxidase chr17 GO:0016491 Not Cancer Driver No 112 0.147 101 13 0.129 0
AOX1 AOX1 Q06278 Aldehyde oxidase chr2 GO:0016491 Not Cancer Driver No 238 0.178 70 11 0.157 0
APEX1_ENST00000555414 APEX1 P27695 DNA-(apurinic or apyrimidinic site) endonuclease chr14 GO:0016491 Not Cancer Driver No 34 0.107 103 14 0.136 0
ASPDH ASPDH A6ND91 Aspartate dehydrogenase domain-containing protein chr19 GO:0016491 Not Cancer Driver No 27 0.095 81 5 0.062 0
ASPH ASPH Q12797 Aspartyl/asparaginyl beta-hydroxylase chr8 GO:0016491 Not Cancer Driver No 109 0.144 373 53 0.142 1
BBOX1_ENST00000525090 BBOX1 O75936 Gamma-butyrobetaine dioxygenase chr11 GO:0016491 Not Cancer Driver No 59 0.152 0 0 0.0 0
BCKDHA BCKDHA P12694 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial chr19 GO:0016491 Not Cancer Driver No 53 0.119 121 18 0.149 11
BCKDHB BCKDHB P21953 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial chr6 GO:0016491 Not Cancer Driver No 47 0.12 23 3 0.13 5
BCO1 BCO1 Q9HAY6 Beta,beta-carotene 15,15'-dioxygenase chr16 GO:0016491 Not Cancer Driver No 78 0.143 37 5 0.135 1
BCO2 BCO2 Q9BYV7 Carotenoid-cleaving dioxygenase, mitochondrial chr11 GO:0016491 Not Cancer Driver No 79 0.136 14 1 0.071 0
BDH1 BDH1 Q02338 D-beta-hydroxybutyrate dehydrogenase, mitochondrial chr3 GO:0016491 Not Cancer Driver No 44 0.128 15 1 0.067 0
BDH2 BDH2 Q9BUT1 3-hydroxybutyrate dehydrogenase type 2 chr4 GO:0016491 Not Cancer Driver No 24 0.098 22 1 0.045 0
BLVRA BLVRA P53004 Biliverdin reductase A chr7 GO:0016491 Not Cancer Driver No 34 0.115 6 1 0.167 0
BLVRB BLVRB P30043 Flavin reductase (NADPH) chr19 GO:0016491 Not Cancer Driver No 16 0.078 56 6 0.107 0
CAT CAT P04040 Catalase chr11 GO:0016491 Not Cancer Driver No 70 0.133 176 18 0.102 0
CBR1 CBR1 P16152 Carbonyl reductase [NADPH] 1 chr21 GO:0016491 Not Cancer Driver No 27 0.097 62 11 0.177 0
CBR3 CBR3 O75828 Carbonyl reductase [NADPH] 3 chr21 GO:0016491 Not Cancer Driver No 26 0.094 66 6 0.091 0
CBR4 CBR4 Q8N4T8 3-oxoacyl-[acyl-carrier-protein] reductase chr4 GO:0016491 Not Cancer Driver No 15 0.063 4 0 0.0 0
CBS_ENST00000359624 CBS P35520 Cystathionine beta-synthase chr21 GO:0016491 Not Cancer Driver No 61 0.111 160 19 0.119 103
CCS CCS O14618 Copper chaperone for superoxide dismutase chr11 GO:0016491 Not Cancer Driver No 28 0.102 105 10 0.095 0
CDO1 CDO1 Q16878 Cysteine dioxygenase type 1 chr5 GO:0016491 Not Cancer Driver No 37 0.185 43 4 0.093 0
CH25H CH25H O95992 Cholesterol 25-hydroxylase chr10 GO:0016491 Not Cancer Driver No 37 0.136 0 0 0.0 0
CHCHD4_ENST00000396914 CHCHD4 Q8N4Q1 Mitochondrial intermembrane space import and assembly protein 40 chr3 GO:0016491 Not Cancer Driver No 18 0.127 82 8 0.098 0
CHDH CHDH Q8NE62 Choline dehydrogenase, mitochondrial chr3 GO:0016491 Not Cancer Driver No 59 0.099 116 7 0.06 0
CLIC2 CLIC2 O15247 Chloride intracellular channel protein 2 chrX GO:0016491 Not Cancer Driver No 46 0.186 58 6 0.103 1
COQ6 COQ6 Q9Y2Z9 Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial chr14 GO:0016491 Not Cancer Driver No 58 0.124 20 2 0.1 2
COQ7_ENST00000568985 COQ7 Q99807 5-demethoxyubiquinone hydroxylase, mitochondrial chr16 GO:0016491 Not Cancer Driver No 27 0.124 5 1 0.2 1
COX15 COX15 Q7KZN9 Cytochrome c oxidase assembly protein COX15 homolog chr10 GO:0016491 Not Cancer Driver No 48 0.117 0 0 0.0 2
COX4I1 COX4I1 P13073 Cytochrome c oxidase subunit 4 isoform 1, mitochondrial chr16 GO:0016491 Not Cancer Driver No 17 0.101 5 1 0.2 1
COX4I2 COX4I2 Q96KJ9 Cytochrome c oxidase subunit 4 isoform 2, mitochondrial chr20 GO:0016491 Not Cancer Driver No 26 0.152 36 4 0.111 1
COX5A COX5A P20674 Cytochrome c oxidase subunit 5A, mitochondrial chr15 GO:0016491 Not Cancer Driver No 20 0.133 14 5 0.357 1
COX5B COX5B P10606 Cytochrome c oxidase subunit 5B, mitochondrial chr2 GO:0016491 Not Cancer Driver No 16 0.124 58 6 0.103 0
COX6A1 COX6A1 P12074 Cytochrome c oxidase subunit 6A1, mitochondrial chr12 GO:0016491 Not Cancer Driver No 17 0.156 48 5 0.104 0
COX6A2 COX6A2 Q02221 Cytochrome c oxidase subunit 6A2, mitochondrial chr16 GO:0016491 Not Cancer Driver No 14 0.144 42 8 0.19 2
COX6B1_ENST00000592141 COX6B1 P14854 Cytochrome c oxidase subunit 6B1 chr19 GO:0016491 Not Cancer Driver No 15 0.174 23 6 0.261 2
COX7A1 COX7A1 P24310 Cytochrome c oxidase subunit 7A1, mitochondrial chr19 GO:0016491 Not Cancer Driver No 10 0.127 0 0 0.0 0
COX7A2L COX7A2L O14548 Cytochrome c oxidase subunit 7A-related protein, mitochondrial chr2 GO:0016491 Not Cancer Driver No 13 0.114 0 0 0.0 0
COX7B COX7B P24311 Cytochrome c oxidase subunit 7B, mitochondrial chrX GO:0016491 Not Cancer Driver No 19 0.237 28 7 0.25 0
COX7B2 COX7B2 Q8TF08 Cytochrome c oxidase subunit 7B2, mitochondrial chr4 GO:0016491 Not Cancer Driver No 19 0.235 6 0 0.0 0
COX8A COX8A P10176 Cytochrome c oxidase subunit 8A, mitochondrial chr11 GO:0016491 Not Cancer Driver No 10 0.145 1 0 0.0 0
CP CP P00450 Ceruloplasmin chr3 GO:0016491 Not Cancer Driver No 145 0.136 197 30 0.152 0
CPOX CPOX P36551 Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial chr3 GO:0016491 Not Cancer Driver No 49 0.108 126 7 0.056 17
CRAT CRAT P43155 Carnitine O-acetyltransferase chr9 GO:0016491 Not Cancer Driver No 74 0.118 27 4 0.148 0
CRYL1 CRYL1 Q9Y2S2 Lambda-crystallin homolog chr13 GO:0016491 Not Cancer Driver No 36 0.113 29 3 0.103 0
CRYM CRYM Q14894 Ketimine reductase mu-crystallin chr16 GO:0016491 Not Cancer Driver No 34 0.108 10 0 0.0 1
CRYZL1 CRYZL1 O95825 Quinone oxidoreductase-like protein 1 chr21 GO:0016491 Not Cancer Driver No 30 0.086 1 0 0.0 0
CRYZ_ENST00000340866 CRYZ Q08257 Quinone oxidoreductase chr1 GO:0016491 Not Cancer Driver No 49 0.149 0 0 0.0 0
CYB561A3_ENST00000294072 CYB561A3 Q8NBI2 Lysosomal membrane ascorbate-dependent ferrireductase CYB561A3 chr11 GO:0016491 Not Cancer Driver No 30 0.124 1 0 0.0 0
CYB561D1_ENST00000420578 CYB561D1 Q8N8Q1 Probable transmembrane reductase CYB561D1 chr1 GO:0016491 Not Cancer Driver No 17 0.074 0 0 0.0 0
CYB561D2_ENST00000232508 CYB561D2 O14569 Transmembrane reductase CYB561D2 chr3 GO:0016491 Not Cancer Driver No 9 0.041 0 0 0.0 0
CYB561_ENST00000392976 CYB561 P49447 Transmembrane ascorbate-dependent reductase CYB561 chr17 GO:0016491 Not Cancer Driver No 28 0.112 6 0 0.0 1
CYB5A CYB5A P00167 Cytochrome b5 chr18 GO:0016491 Not Cancer Driver No 20 0.149 70 12 0.171 1
CYB5B CYB5B O43169 Cytochrome b5 type B chr16 GO:0016491 Not Cancer Driver No 17 0.113 58 2 0.034 0
CYB5R1 CYB5R1 Q9UHQ9 NADH-cytochrome b5 reductase 1 chr1 GO:0016491 Not Cancer Driver No 43 0.141 22 1 0.045 0
CYB5R2_ENST00000299498 CYB5R2 Q6BCY4 NADH-cytochrome b5 reductase 2 chr11 GO:0016491 Not Cancer Driver No 34 0.123 78 10 0.128 0
CYB5R3_ENST00000352397 CYB5R3 P00387 NADH-cytochrome b5 reductase 3 chr22 GO:0016491 Not Cancer Driver No 42 0.14 24 3 0.125 9
CYB5R4 CYB5R4 Q7L1T6 Cytochrome b5 reductase 4 chr6 GO:0016491 Not Cancer Driver No 73 0.14 56 10 0.179 0
CYB5RL CYB5RL Q6IPT4 NADH-cytochrome b5 reductase-like chr1 GO:0016491 Not Cancer Driver No 40 0.127 35 5 0.143 0
CYBA CYBA P13498 Cytochrome b-245 light chain chr16 GO:0016491 Not Cancer Driver No 26 0.133 66 2 0.03 12
CYBB CYBB P04839 Cytochrome b-245 heavy chain chrX GO:0016491 Not Cancer Driver No 109 0.191 11 3 0.273 65
CYBRD1 CYBRD1 Q53TN4 Plasma membrane ascorbate-dependent reductase CYBRD1 chr2 GO:0016491 Not Cancer Driver No 34 0.119 59 10 0.169 0
CYGB CYGB Q8WWM9 Cytoglobin chr17 GO:0016491 Not Cancer Driver No 32 0.168 47 5 0.106 0
CYP11A1 CYP11A1 P05108 Cholesterol side-chain cleavage enzyme, mitochondrial chr15 GO:0016491 Not Cancer Driver No 92 0.177 27 6 0.222 6
CYP11B1 CYP11B1 P15538 Cytochrome P450 11B1, mitochondrial chr8 GO:0016491 Not Cancer Driver No 177 0.352 7 1 0.143 50
CYP11B2 CYP11B2 P19099 Cytochrome P450 11B2, mitochondrial chr8 GO:0016491 Not Cancer Driver No 148 0.294 6 0 0.0 6
CYP17A1 CYP17A1 P05093 Steroid 17-alpha-hydroxylase/17,20 lyase chr10 GO:0016491 Not Cancer Driver No 64 0.126 34 2 0.059 26
CYP19A1_ENST00000396404 CYP19A1 P11511 Aromatase chr15 GO:0016491 Not Cancer Driver No 91 0.181 2 1 0.5 5
CYP1A1 CYP1A1 P04798 Cytochrome P450 1A1 chr15 GO:0016491 Not Cancer Driver No 81 0.158 17 2 0.118 0
CYP1A2 CYP1A2 P05177 Cytochrome P450 1A2 chr15 GO:0016491 Not Cancer Driver No 93 0.18 23 3 0.13 0
CYP1B1 CYP1B1 Q16678 Cytochrome P450 1B1 chr2 GO:0016491 Not Cancer Driver No 61 0.112 31 3 0.097 40
CYP21A2_ENST00000643666 CYP21A2 P08686 Steroid 21-hydroxylase chr6 GO:0016491 Not Cancer Driver No 70 0.142 49 16 0.327 66
CYP24A1 CYP24A1 Q07973 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial chr20 GO:0016491 Not Cancer Driver No 74 0.144 77 5 0.065 4
CYP26A1 CYP26A1 O43174 Cytochrome P450 26A1 chr10 GO:0016491 Not Cancer Driver No 84 0.169 9 1 0.111 0
CYP26B1 CYP26B1 Q9NR63 Cytochrome P450 26B1 chr2 GO:0016491 Not Cancer Driver No 113 0.221 10 3 0.3 2
CYP26C1 CYP26C1 Q6V0L0 Cytochrome P450 26C1 chr10 GO:0016491 Not Cancer Driver No 32 0.061 56 6 0.107 0
CYP27A1 CYP27A1 Q02318 Sterol 26-hydroxylase, mitochondrial chr2 GO:0016491 Not Cancer Driver No 69 0.13 47 11 0.234 7
CYP27B1 CYP27B1 O15528 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial chr12 GO:0016491 Not Cancer Driver No 71 0.14 79 13 0.165 18
CYP2A13 CYP2A13 Q16696 Cytochrome P450 2A13 chr19 GO:0016491 Not Cancer Driver No 122 0.247 38 9 0.237 0
CYP2A6 CYP2A6 P11509 Cytochrome P450 2A6 chr19 GO:0016491 Not Cancer Driver No 107 0.217 40 10 0.25 0
CYP2A7 CYP2A7 P20853 Cytochrome P450 2A7 chr19 GO:0016491 Not Cancer Driver No 95 0.192 39 9 0.231 0
CYP2B6 CYP2B6 P20813 Cytochrome P450 2B6 chr19 GO:0016491 Not Cancer Driver No 137 0.279 39 13 0.333 0
CYP2C18 CYP2C18 P33260 Cytochrome P450 2C18 chr10 GO:0016491 Not Cancer Driver No 114 0.233 11 1 0.091 0
CYP2C19 CYP2C19 P33261 Cytochrome P450 2C19 chr10 GO:0016491 Not Cancer Driver No 157 0.32 32 12 0.375 0
CYP2C8 CYP2C8 P10632 Cytochrome P450 2C8 chr10 GO:0016491 Census, Compendium Yes 113 0.231 30 11 0.367 0
CYP2C9 CYP2C9 P11712 Cytochrome P450 2C9 chr10 GO:0016491 Not Cancer Driver No 122 0.249 36 14 0.389 0
CYP2D6_ENST00000645361 CYP2D6 P10635 Cytochrome P450 2D6 chr22 GO:0016491 Not Cancer Driver No 76 0.153 66 8 0.121 0
CYP2D7 CYP2D7 A0A087X1C5 Putative cytochrome P450 2D7 chr22 GO:0016491 Not Cancer Driver No 74 0.144 60 6 0.1 0
CYP2E1_ENST00000252945 CYP2E1 P05181 Cytochrome P450 2E1 chr10 GO:0016491 Not Cancer Driver No 87 0.176 21 6 0.286 0
CYP2F1 CYP2F1 P24903 Cytochrome P450 2F1 chr19 GO:0016491 Not Cancer Driver No 85 0.173 2 0 0.0 0
CYP2J2 CYP2J2 P51589 Cytochrome P450 2J2 chr1 GO:0016491 Not Cancer Driver No 58 0.116 63 6 0.095 0
CYP2R1 CYP2R1 Q6VVX0 Vitamin D 25-hydroxylase chr11 GO:0016491 Not Cancer Driver No 53 0.106 5 1 0.2 1
CYP2S1 CYP2S1 Q96SQ9 Cytochrome P450 2S1 chr19 GO:0016491 Not Cancer Driver No 75 0.149 46 10 0.217 0
CYP2U1 CYP2U1 Q7Z449 Cytochrome P450 2U1 chr4 GO:0016491 Not Cancer Driver No 37 0.068 38 2 0.053 4
CYP2W1 CYP2W1 Q8TAV3 Cytochrome P450 2W1 chr7 GO:0016491 Not Cancer Driver No 51 0.104 55 6 0.109 0
CYP39A1 CYP39A1 Q9NYL5 24-hydroxycholesterol 7-alpha-hydroxylase chr6 GO:0016491 Not Cancer Driver No 61 0.13 3 0 0.0 0
CYP3A4 CYP3A4 P08684 Cytochrome P450 3A4 chr7 GO:0016491 Not Cancer Driver No 91 0.181 22 2 0.091 1
CYP3A43_ENST00000354829 CYP3A43 Q9HB55 Cytochrome P450 3A43 chr7 GO:0016491 Not Cancer Driver No 79 0.157 5 0 0.0 0
CYP3A5 CYP3A5 P20815 Cytochrome P450 3A5 chr7 GO:0016491 Not Cancer Driver No 67 0.133 38 5 0.132 0
CYP3A7 CYP3A7 P24462 Cytochrome P450 3A7 chr7 GO:0016491 Not Cancer Driver No 91 0.181 17 6 0.353 0
CYP46A1 CYP46A1 Q9Y6A2 Cholesterol 24-hydroxylase chr14 GO:0016491 Not Cancer Driver No 92 0.184 23 4 0.174 0
CYP4A11 CYP4A11 Q02928 Cytochrome P450 4A11 chr1 GO:0016491 Not Cancer Driver No 131 0.252 24 8 0.333 0
CYP4A22 CYP4A22 Q5TCH4 Cytochrome P450 4A22 chr1 GO:0016491 Not Cancer Driver No 116 0.224 26 6 0.231 0
CYP4B1_ENST00000271153 CYP4B1 P13584 Cytochrome P450 4B1 chr1 GO:0016491 Not Cancer Driver No 124 0.243 8 2 0.25 0
CYP4F11 CYP4F11 Q9HBI6 Cytochrome P450 4F11 chr19 GO:0016491 Not Cancer Driver No 132 0.252 11 2 0.182 0
CYP4F12_ENST00000324632 CYP4F12 Q9HCS2 Cytochrome P450 4F12 chr19 GO:0016491 Not Cancer Driver No 138 0.263 18 4 0.222 0
CYP4F2 CYP4F2 P78329 Cytochrome P450 4F2 chr19 GO:0016491 Not Cancer Driver No 136 0.262 17 3 0.176 0
CYP4F3 CYP4F3 Q08477 Cytochrome P450 4F3 chr19 GO:0016491 Not Cancer Driver No 125 0.24 15 7 0.467 0
CYP4F8 CYP4F8 P98187 Cytochrome P450 4F8 chr19 GO:0016491 Not Cancer Driver No 108 0.208 28 10 0.357 0
CYP4V2 CYP4V2 Q6ZWL3 Cytochrome P450 4V2 chr4 GO:0016491 Not Cancer Driver No 67 0.128 46 9 0.196 8
CYP4X1 CYP4X1 Q8N118 Cytochrome P450 4X1 chr1 GO:0016491 Not Cancer Driver No 86 0.169 14 7 0.5 0
CYP4Z1 CYP4Z1 Q86W10 Cytochrome P450 4Z1 chr1 GO:0016491 Not Cancer Driver No 106 0.21 14 8 0.571 0
CYP51A1 CYP51A1 Q16850 Lanosterol 14-alpha demethylase chr7 GO:0016491 Not Cancer Driver No 49 0.096 7 2 0.286 0
CYP7A1 CYP7A1 P22680 Cytochrome P450 7A1 chr8 GO:0016491 Not Cancer Driver No 109 0.216 48 8 0.167 0
CYP7B1 CYP7B1 O75881 Cytochrome P450 7B1 chr8 GO:0016491 Not Cancer Driver No 133 0.263 0 0 0.0 11
CYP8B1 CYP8B1 Q9UNU6 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase chr3 GO:0016491 Not Cancer Driver No 91 0.182 5 1 0.2 0
D2HGDH D2HGDH Q8N465 D-2-hydroxyglutarate dehydrogenase, mitochondrial chr2 GO:0016491 Not Cancer Driver No 61 0.117 46 1 0.022 0
DAO DAO P14920 D-amino-acid oxidase chr12 GO:0016491 Not Cancer Driver No 103 0.297 28 13 0.464 0
DBH DBH P09172 Dopamine beta-hydroxylase chr9 GO:0016491 Not Cancer Driver No 125 0.203 71 17 0.239 3
DCT_ENST00000377028 DCT P40126 L-dopachrome tautomerase chr13 GO:0016491 Not Cancer Driver No 113 0.218 19 4 0.211 2
DCXR DCXR Q7Z4W1 L-xylulose reductase chr17 GO:0016491 Not Cancer Driver No 14 0.057 10 1 0.1 0
DECR1 DECR1 Q16698 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial chr8 GO:0016491 Not Cancer Driver No 38 0.113 11 0 0.0 0
DECR2 DECR2 Q9NUI1 Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing] chr16 GO:0016491 Not Cancer Driver No 44 0.151 36 2 0.056 0
DEGS1_ENST00000391877 DEGS1 O15121 Sphingolipid delta(4)-desaturase DES1 chr1 GO:0016491 Not Cancer Driver No 50 0.155 2 0 0.0 4
DEGS2 DEGS2 Q6QHC5 Sphingolipid delta(4)-desaturase/C4-monooxygenase DES2 chr14 GO:0016491 Not Cancer Driver No 43 0.133 0 0 0.0 0
DHCR24 DHCR24 Q15392 Delta(24)-sterol reductase chr1 GO:0016491 Not Cancer Driver No 55 0.107 0 0 0.0 6
DHCR7 DHCR7 Q9UBM7 7-dehydrocholesterol reductase chr11 GO:0016491 Not Cancer Driver No 85 0.179 7 1 0.143 53
DHDH DHDH Q9UQ10 Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase chr19 GO:0016491 Not Cancer Driver No 54 0.162 18 2 0.111 0
DHFR DHFR P00374 Dihydrofolate reductase chr5 GO:0016491 Not Cancer Driver No 16 0.086 12 2 0.167 2
DHFR2_ENST00000314636 DHFR2 Q86XF0 Dihydrofolate reductase 2, mitochondrial chr3 GO:0016491 Not Cancer Driver No 25 0.134 20 0 0.0 0
DHODH DHODH Q02127 Dihydroorotate dehydrogenase (quinone), mitochondrial chr16 GO:0016491 Not Cancer Driver No 44 0.111 96 11 0.115 10
DHRS1 DHRS1 Q96LJ7 Dehydrogenase/reductase SDR family member 1 chr14 GO:0016491 Not Cancer Driver No 22 0.07 5 0 0.0 0
DHRS12 DHRS12 A0PJE2 Dehydrogenase/reductase SDR family member 12 chr13 GO:0016491 Not Cancer Driver No 22 0.069 101 9 0.089 0
DHRS13 DHRS13 Q6UX07 Dehydrogenase/reductase SDR family member 13 chr17 GO:0016491 Not Cancer Driver No 26 0.069 101 8 0.079 0
DHRS2_ENST00000250383 DHRS2 Q13268 Dehydrogenase/reductase SDR family member 2, mitochondrial chr14 GO:0016491 Not Cancer Driver No 47 0.168 0 0 0.0 0
DHRS3 DHRS3 O75911 Short-chain dehydrogenase/reductase 3 chr1 GO:0016491 Not Cancer Driver No 33 0.109 0 0 0.0 0
DHRS4 DHRS4 Q9BTZ2 Dehydrogenase/reductase SDR family member 4 chr14 GO:0016491 Not Cancer Driver No 30 0.108 38 4 0.105 0
DHRS4L2 DHRS4L2 Q6PKH6 Dehydrogenase/reductase SDR family member 4-like 2 chr14 GO:0016491 Not Cancer Driver No 24 0.103 32 4 0.125 0
DHRS7B DHRS7B Q6IAN0 Dehydrogenase/reductase SDR family member 7B chr17 GO:0016491 Not Cancer Driver No 37 0.114 17 0 0.0 0
DHRS7C DHRS7C A6NNS2 Dehydrogenase/reductase SDR family member 7C chr17 GO:0016491 Not Cancer Driver No 80 0.256 0 0 0.0 0
DHRS7_ENST00000557185 DHRS7 Q9Y394 Dehydrogenase/reductase SDR family member 7 chr14 GO:0016491 Not Cancer Driver No 37 0.109 10 0 0.0 0
DHRS9_ENST00000602501 DHRS9 Q9BPW9 Dehydrogenase/reductase SDR family member 9 chr2 GO:0016491 Not Cancer Driver No 67 0.21 3 0 0.0 0
DHRSX DHRSX Q8N5I4 Dehydrogenase/reductase SDR family member on chromosome X chrX GO:0016491 Not Cancer Driver No 53 0.161 5 0 0.0 0
DHTKD1 DHTKD1 Q96HY7 2-oxoadipate dehydrogenase complex component E1 chr10 GO:0016491 Not Cancer Driver No 119 0.129 117 15 0.128 2
DIO1_ENST00000613679 DIO1 P49895 Type I iodothyronine deiodinase chr1 GO:0016491 Not Cancer Driver No 28 0.112 0 0 0.0 0
DIO2_ENST00000557010 DIO2 Q92813 Type II iodothyronine deiodinase chr14 GO:0016491 Not Cancer Driver No 73 0.267 44 4 0.091 0
DIO3 DIO3 P55073 Thyroxine 5-deiodinase chr14 GO:0016491 Not Cancer Driver No 88 0.289 71 18 0.254 0
DLAT DLAT P10515 Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial chr11 GO:0016491 Not Cancer Driver No 63 0.097 294 42 0.143 0
DLD DLD P09622 Dihydrolipoyl dehydrogenase, mitochondrial chr7 GO:0016491 Not Cancer Driver No 67 0.132 17 0 0.0 10
DMGDH DMGDH Q9UI17 Dimethylglycine dehydrogenase, mitochondrial chr5 GO:0016491 Not Cancer Driver No 155 0.179 74 12 0.162 1
DNAJC10 DNAJC10 Q8IXB1 DnaJ homolog subfamily C member 10 chr2 GO:0016491 Not Cancer Driver No 110 0.139 36 3 0.083 0
DOHH DOHH Q9BU89 Deoxyhypusine hydroxylase chr19 GO:0016491 Not Cancer Driver No 30 0.099 56 6 0.107 0
DPYD DPYD Q12882 Dihydropyrimidine dehydrogenase [NADP(+)] chr1 GO:0016491 Not Cancer Driver No 303 0.296 77 23 0.299 3
DUOX1 DUOX1 Q9NRD9 Dual oxidase 1 chr15 GO:0016491 Not Cancer Driver No 193 0.124 158 17 0.108 0
DUOX2 DUOX2 Q9NRD8 Dual oxidase 2 chr15 GO:0016491 Not Cancer Driver No 245 0.158 182 25 0.137 3
DUS1L_ENST00000306796 DUS1L Q6P1R4 tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]-like chr17 GO:0016491 Not Cancer Driver No 52 0.11 110 10 0.091 0
DUS2 DUS2 Q9NX74 tRNA-dihydrouridine(20) synthase [NAD(P)+]-like chr16 GO:0016491 Not Cancer Driver No 48 0.097 117 10 0.085 0
DUS3L DUS3L Q96G46 tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like chr19 GO:0016491 Not Cancer Driver No 82 0.126 234 27 0.115 0
DUS4L DUS4L O95620 tRNA-dihydrouridine(20a/20b) synthase [NAD(P)+]-like chr7 GO:0016491 Not Cancer Driver No 38 0.12 3 0 0.0 0
EGLN1 EGLN1 Q9GZT9 Egl nine homolog 1 chr1 GO:0016491 Not Cancer Driver No 35 0.082 206 8 0.039 2
EGLN2_ENST00000303961 EGLN2 Q96KS0 Prolyl hydroxylase EGLN2 chr19 GO:0016491 Not Cancer Driver No 52 0.128 201 17 0.085 0
EGLN3 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 GO:0016491 Not Cancer Driver No 33 0.138 13 0 0.0 0
EHHADH EHHADH Q08426 Peroxisomal bifunctional enzyme chr3 GO:0016491 Not Cancer Driver No 116 0.16 74 14 0.189 1
ENOX1 ENOX1 Q8TC92 Ecto-NOX disulfide-thiol exchanger 1 chr13 GO:0016491 Not Cancer Driver No 130 0.202 321 70 0.218 0
ENOX2 ENOX2 Q16206 Ecto-NOX disulfide-thiol exchanger 2 chrX GO:0016491 Not Cancer Driver No 103 0.169 239 41 0.172 0
EPX EPX P11678 Eosinophil peroxidase chr17 GO:0016491 Not Cancer Driver No 144 0.201 55 6 0.109 1
ERO1A ERO1A Q96HE7 ERO1-like protein alpha chr14 GO:0016491 Not Cancer Driver No 48 0.103 32 5 0.156 0
ERO1B ERO1B Q86YB8 ERO1-like protein beta chr1 GO:0016491 Not Cancer Driver No 59 0.126 20 2 0.1 0
ETFA ETFA P13804 Electron transfer flavoprotein subunit alpha, mitochondrial chr15 GO:0016491 Not Cancer Driver No 30 0.09 34 2 0.059 3
ETFDH ETFDH Q16134 Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial chr4 GO:0016491 Not Cancer Driver No 61 0.099 64 4 0.062 12
ETHE1 ETHE1 O95571 Persulfide dioxygenase ETHE1, mitochondrial chr19 GO:0016491 Not Cancer Driver No 21 0.083 6 0 0.0 9
F8 F8 P00451 Coagulation factor VIII chrX GO:0016491 Not Cancer Driver No 414 0.176 931 174 0.187 472
FA2H FA2H Q7L5A8 Fatty acid 2-hydroxylase chr16 GO:0016491 Not Cancer Driver No 33 0.089 73 0 0.0 3
FADS2 FADS2 O95864 Acyl-CoA 6-desaturase chr11 GO:0016491 Not Cancer Driver No 59 0.133 42 1 0.024 0
FADS3 FADS3 Q9Y5Q0 Fatty acid desaturase 3 chr11 GO:0016491 Not Cancer Driver No 54 0.121 47 2 0.043 0
FADS6_ENST00000614223 FADS6 Q8N9I5 Fatty acid desaturase 6 chr17 GO:0016491 Not Cancer Driver No 36 0.101 27 2 0.074 0
FAR1 FAR1 Q8WVX9 Fatty acyl-CoA reductase 1 chr11 GO:0016491 Not Cancer Driver No 66 0.128 0 0 0.0 4
FAR2 FAR2 Q96K12 Fatty acyl-CoA reductase 2 chr12 GO:0016491 Not Cancer Driver No 63 0.122 0 0 0.0 0
FASN FASN P49327 Fatty acid synthase chr17 GO:0016491 Not Cancer Driver No 291 0.116 309 42 0.136 0
FAXDC2 FAXDC2 Q96IV6 Fatty acid hydroxylase domain-containing protein 2 chr5 GO:0016491 Not Cancer Driver No 39 0.117 9 0 0.0 0
FDXR_ENST00000293195 FDXR P22570 NADPH:adrenodoxin oxidoreductase, mitochondrial chr17 GO:0016491 Not Cancer Driver No 68 0.138 102 14 0.137 4
FMO1 FMO1 Q01740 Dimethylaniline monooxygenase [N-oxide-forming] 1 chr1 GO:0016491 Not Cancer Driver No 133 0.25 3 0 0.0 0
FMO2 FMO2 Q99518 Flavin-containing monooxygenase 2 chr1 GO:0016491 Not Cancer Driver No 125 0.234 3 0 0.0 0
FMO3 FMO3 P31513 Dimethylaniline monooxygenase [N-oxide-forming] 3 chr1 GO:0016491 Not Cancer Driver No 146 0.274 15 9 0.6 8
FMO4 FMO4 P31512 Dimethylaniline monooxygenase [N-oxide-forming] 4 chr1 GO:0016491 Not Cancer Driver No 110 0.197 8 5 0.625 0
FMO5 FMO5 P49326 Flavin-containing monooxygenase 5 chr1 GO:0016491 Not Cancer Driver No 82 0.154 32 4 0.125 0
FOXRED1 FOXRED1 Q96CU9 FAD-dependent oxidoreductase domain-containing protein 1 chr11 GO:0016491 Not Cancer Driver No 66 0.136 62 11 0.177 2
FOXRED2 FOXRED2 Q8IWF2 FAD-dependent oxidoreductase domain-containing protein 2 chr22 GO:0016491 Not Cancer Driver No 97 0.142 48 5 0.104 0
FRRS1_ENST00000646001 FRRS1 Q6ZNA5 Ferric-chelate reductase 1 chr1 GO:0016491 Not Cancer Driver No 59 0.1 40 6 0.15 0
FTO FTO Q9C0B1 Alpha-ketoglutarate-dependent dioxygenase FTO chr16 GO:0016491 Not Cancer Driver No 67 0.133 53 10 0.189 3
G6PD_ENST00000621232 G6PD P11413 Glucose-6-phosphate 1-dehydrogenase chrX GO:0016491 Not Cancer Driver No 86 0.167 28 3 0.107 58
GAPDH GAPDH P04406 Glyceraldehyde-3-phosphate dehydrogenase chr12 GO:0016491 Not Cancer Driver No 39 0.116 24 3 0.125 0
GAPDHS GAPDHS O14556 Glyceraldehyde-3-phosphate dehydrogenase, testis-specific chr19 GO:0016491 Not Cancer Driver No 71 0.174 111 19 0.171 0
GCDH_ENST00000591470 GCDH Q92947 Glutaryl-CoA dehydrogenase, mitochondrial chr19 GO:0016491 Not Cancer Driver No 57 0.13 37 5 0.135 58
GCLM GCLM P48507 Glutamate--cysteine ligase regulatory subunit chr1 GO:0016491 Not Cancer Driver No 32 0.117 31 3 0.097 0
GFER GFER P55789 FAD-linked sulfhydryl oxidase ALR chr16 GO:0016491 Not Cancer Driver No 10 0.049 97 4 0.041 1
GFOD1 GFOD1 Q9NXC2 Glucose-fructose oxidoreductase domain-containing protein 1 chr6 GO:0016491 Not Cancer Driver No 57 0.146 35 2 0.057 0
GFOD2 GFOD2 Q3B7J2 Glucose-fructose oxidoreductase domain-containing protein 2 chr16 GO:0016491 Not Cancer Driver No 61 0.158 37 8 0.216 0
GLDC GLDC P23378 Glycine dehydrogenase (decarboxylating), mitochondrial chr9 GO:0016491 Not Cancer Driver No 152 0.149 112 7 0.062 22
GLRX2_ENST00000367439 GLRX2 Q9NS18 Glutaredoxin-2, mitochondrial chr1 GO:0016491 Not Cancer Driver No 12 0.073 10 1 0.1 0
GLRX3 GLRX3 O76003 Glutaredoxin-3 chr10 GO:0016491 Not Cancer Driver No 52 0.155 24 4 0.167 0
GLRX5 GLRX5 Q86SX6 Glutaredoxin-related protein 5, mitochondrial chr14 GO:0016491 Not Cancer Driver No 7 0.045 23 0 0.0 2
GLRX_ENST00000505427 GLRX P35754 Glutaredoxin-1 chr5 GO:0016491 Not Cancer Driver No 14 0.132 0 0 0.0 0
GLUD1 GLUD1 P00367 Glutamate dehydrogenase 1, mitochondrial chr10 GO:0016491 Not Cancer Driver No 50 0.09 107 14 0.131 13
GLUD2 GLUD2 P49448 Glutamate dehydrogenase 2, mitochondrial chrX GO:0016491 Not Cancer Driver No 145 0.26 117 37 0.316 0
GMPR GMPR P36959 GMP reductase 1 chr6 GO:0016491 Not Cancer Driver No 52 0.151 17 3 0.176 0
GMPR2_ENST00000399440 GMPR2 Q9P2T1 GMP reductase 2 chr14 GO:0016491 Not Cancer Driver No 30 0.086 9 1 0.111 0
GPD1 GPD1 P21695 Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic chr12 GO:0016491 Not Cancer Driver No 59 0.169 2 0 0.0 1
GPD1L GPD1L Q8N335 Glycerol-3-phosphate dehydrogenase 1-like protein chr3 GO:0016491 Not Cancer Driver No 40 0.114 13 1 0.077 0
GPD2_ENST00000438166 GPD2 P43304 Glycerol-3-phosphate dehydrogenase, mitochondrial chr2 GO:0016491 Not Cancer Driver No 88 0.121 67 7 0.104 0
GPHN_ENST00000315266 GPHN Q9NQX3 Gephyrin chr14 GO:0016491 Census Yes 126 0.171 305 41 0.134 2
GPX1_ENST00000620890 GPX1 P07203 Glutathione peroxidase 1 chr3 GO:0016491 Not Cancer Driver No 38 0.187 12 1 0.083 0
GPX2_ENST00000612794 GPX2 P18283 Glutathione peroxidase 2 chr14 GO:0016491 Not Cancer Driver No 26 0.137 0 0 0.0 0
GPX3_ENST00000622181 GPX3 P22352 Glutathione peroxidase 3 chr5 GO:0016491 Not Cancer Driver No 29 0.128 7 0 0.0 0
GPX4_ENST00000616066 GPX4 P36969 Phospholipid hydroperoxide glutathione peroxidase chr19 GO:0016491 Not Cancer Driver No 14 0.071 0 0 0.0 0
GPX5 GPX5 O75715 Epididymal secretory glutathione peroxidase chr6 GO:0016491 Not Cancer Driver No 74 0.335 9 4 0.444 0
GPX6_ENST00000612264 GPX6 P59796 Glutathione peroxidase 6 chr6 GO:0016491 Not Cancer Driver No 66 0.299 0 0 0.0 0
GPX7 GPX7 Q96SL4 Glutathione peroxidase 7 chr1 GO:0016491 Not Cancer Driver No 24 0.128 6 1 0.167 0
GPX8 GPX8 Q8TED1 Probable glutathione peroxidase 8 chr5 GO:0016491 Not Cancer Driver No 21 0.1 4 1 0.25 0
GRHPR GRHPR Q9UBQ7 Glyoxylate reductase/hydroxypyruvate reductase chr9 GO:0016491 Not Cancer Driver No 31 0.095 36 4 0.111 0
GRXCR1 GRXCR1 A8MXD5 Glutaredoxin domain-containing cysteine-rich protein 1 chr4 GO:0016491 Not Cancer Driver No 139 0.479 73 45 0.616 4
GSR GSR P00390 Glutathione reductase, mitochondrial chr8 GO:0016491 Not Cancer Driver No 53 0.102 55 5 0.091 1
GSTA1 GSTA1 P08263 Glutathione S-transferase A1 chr6 GO:0016491 Not Cancer Driver No 48 0.216 17 5 0.294 0
GSTK1_ENST00000358406 GSTK1 Q9Y2Q3 Glutathione S-transferase kappa 1 chr7 GO:0016491 Not Cancer Driver No 33 0.146 30 3 0.1 0
GSTM2 GSTM2 P28161 Glutathione S-transferase Mu 2 chr1 GO:0016491 Not Cancer Driver No 26 0.119 5 0 0.0 0
GSTO1 GSTO1 P78417 Glutathione S-transferase omega-1 chr10 GO:0016491 Not Cancer Driver No 26 0.108 18 1 0.056 0
GSTO2 GSTO2 Q9H4Y5 Glutathione S-transferase omega-2 chr10 GO:0016491 Not Cancer Driver No 25 0.103 17 0 0.0 0
GSTP1_ENST00000642444 GSTP1 P09211 Glutathione S-transferase P chr11 GO:0016491 Not Cancer Driver No 32 0.152 0 0 0.0 0
GSTZ1 GSTZ1 O43708 Maleylacetoacetate isomerase chr14 GO:0016491 Not Cancer Driver No 30 0.139 19 2 0.105 2
H6PD_ENST00000377403 H6PD O95479 GDH/6PGL endoplasmic bifunctional protein chr1 GO:0016491 Not Cancer Driver No 96 0.121 39 3 0.077 2
HAAO HAAO P46952 3-hydroxyanthranilate 3,4-dioxygenase chr2 GO:0016491 Not Cancer Driver No 40 0.14 30 2 0.067 0
HADHA HADHA P40939 Trifunctional enzyme subunit alpha, mitochondrial chr2 GO:0016491 Not Cancer Driver No 72 0.094 19 2 0.105 5
HADHB HADHB P55084 Trifunctional enzyme subunit beta, mitochondrial chr2 GO:0016491 Not Cancer Driver No 71 0.15 41 9 0.22 14
HADH_ENST00000309522 HADH Q16836 Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial chr4 GO:0016491 Not Cancer Driver No 33 0.105 22 5 0.227 3
HAO1 HAO1 Q9UJM8 2-Hydroxyacid oxidase 1 chr20 GO:0016491 Not Cancer Driver No 117 0.316 7 2 0.286 0
HAO2_ENST00000325945 HAO2 Q9NYQ3 2-Hydroxyacid oxidase 2 chr1 GO:0016491 Not Cancer Driver No 102 0.291 12 5 0.417 0
HBA2 HBA2 P69905 Hemoglobin subunit alpha chr16 GO:0016491 Not Cancer Driver No 9 0.063 4 0 0.0 0
HBB HBB P68871 Hemoglobin subunit beta chr11 GO:0016491 Not Cancer Driver No 45 0.306 7 2 0.286 5
HBD HBD P02042 Hemoglobin subunit delta chr11 GO:0016491 Not Cancer Driver No 56 0.381 7 2 0.286 0
HBE1_ENST00000396895 HBE1 P02100 Hemoglobin subunit epsilon chr11 GO:0016491 Not Cancer Driver No 44 0.299 0 0 0.0 0
HBG1 HBG1 P69891 Hemoglobin subunit gamma-1 chr11 GO:0016491 Not Cancer Driver No 23 0.156 2 0 0.0 0
HBG2 HBG2 P69892 Hemoglobin subunit gamma-2 chr11 GO:0016491 Not Cancer Driver No 65 0.442 2 0 0.0 6
HBM HBM Q6B0K9 Hemoglobin subunit mu chr16 GO:0016491 Not Cancer Driver No 9 0.064 0 0 0.0 0
HBQ1 HBQ1 P09105 Hemoglobin subunit theta-1 chr16 GO:0016491 Not Cancer Driver No 10 0.07 0 0 0.0 0
HBZ HBZ P02008 Hemoglobin subunit zeta chr16 GO:0016491 Not Cancer Driver No 9 0.063 0 0 0.0 0
HEATR4 HEATR4 Q86WZ0 HEAT repeat-containing protein 4 chr14 GO:0016491 Not Cancer Driver No 133 0.13 298 50 0.168 0
HEPHL1 HEPHL1 Q6MZM0 Ferroxidase HEPHL1 chr11 GO:0016491 Not Cancer Driver No 253 0.218 110 26 0.236 2
HEPH_ENST00000343002 HEPH Q9BQS7 Hephaestin chrX GO:0016491 Not Cancer Driver No 284 0.245 154 46 0.299 0
HGD HGD Q93099 Homogentisate 1,2-dioxygenase chr3 GO:0016491 Not Cancer Driver No 75 0.169 78 23 0.295 68
HIBADH HIBADH P31937 3-hydroxyisobutyrate dehydrogenase, mitochondrial chr7 GO:0016491 Not Cancer Driver No 28 0.083 7 2 0.286 0
HIF1AN HIF1AN Q9NWT6 Hypoxia-inducible factor 1-alpha inhibitor chr10 GO:0016491 Not Cancer Driver No 37 0.106 77 9 0.117 0
HMGCR_ENST00000511206 HMGCR P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase chr5 GO:0016491 Not Cancer Driver No 84 0.095 112 12 0.107 0
HMOX1 HMOX1 P09601 Heme oxygenase 1 chr22 GO:0016491 Not Cancer Driver No 46 0.16 81 13 0.16 0
HMOX2_ENST00000406590 HMOX2 P30519 Heme oxygenase 2 chr16 GO:0016491 Not Cancer Driver No 27 0.085 74 10 0.135 0
HPD HPD P32754 4-hydroxyphenylpyruvate dioxygenase chr12 GO:0016491 Not Cancer Driver No 61 0.155 40 9 0.225 3
HPDL HPDL Q96IR7 4-hydroxyphenylpyruvate dioxygenase-like protein chr1 GO:0016491 Not Cancer Driver No 30 0.081 58 11 0.19 2
HPGD HPGD P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] chr4 GO:0016491 Not Cancer Driver No 32 0.12 4 1 0.25 2
HR HR O43593 Lysine-specific demethylase hairless chr8 GO:0016491 Not Cancer Driver No 130 0.109 587 74 0.126 3
HSD11B1L_ENST00000423665 HSD11B1L Q7Z5J1 Hydroxysteroid 11-beta-dehydrogenase 1-like protein chr19 GO:0016491 Not Cancer Driver No 16 0.051 97 4 0.041 0
HSD11B1_ENST00000367027 HSD11B1 P28845 11-beta-hydroxysteroid dehydrogenase 1 chr1 GO:0016491 Not Cancer Driver No 57 0.195 0 0 0.0 0
HSD11B2 HSD11B2 P80365 11-beta-hydroxysteroid dehydrogenase type 2 chr16 GO:0016491 Not Cancer Driver No 27 0.067 30 0 0.0 14
HSD17B10 HSD17B10 Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 chrX GO:0016491 Not Cancer Driver No 27 0.103 15 3 0.2 11
HSD17B11 HSD17B11 Q8NBQ5 Estradiol 17-beta-dehydrogenase 11 chr4 GO:0016491 Not Cancer Driver No 28 0.093 3 0 0.0 0
HSD17B12 HSD17B12 Q53GQ0 Very-long-chain 3-oxoacyl-CoA reductase chr11 GO:0016491 Not Cancer Driver No 32 0.103 9 0 0.0 0
HSD17B13 HSD17B13 Q7Z5P4 17-beta-hydroxysteroid dehydrogenase 13 chr4 GO:0016491 Not Cancer Driver No 45 0.15 0 0 0.0 0
HSD17B14 HSD17B14 Q9BPX1 17-beta-hydroxysteroid dehydrogenase 14 chr19 GO:0016491 Not Cancer Driver No 33 0.122 42 10 0.238 0
HSD17B1_ENST00000585807 HSD17B1 P14061 17-beta-hydroxysteroid dehydrogenase type 1 chr17 GO:0016491 Not Cancer Driver No 48 0.146 59 28 0.475 0
HSD17B2 HSD17B2 P37059 17-beta-hydroxysteroid dehydrogenase type 2 chr16 GO:0016491 Not Cancer Driver No 55 0.142 6 1 0.167 0
HSD17B3 HSD17B3 P37058 17-beta-hydroxysteroid dehydrogenase type 3 chr9 GO:0016491 Not Cancer Driver No 42 0.135 0 0 0.0 15
HSD17B4_ENST00000256216 HSD17B4 P51659 Peroxisomal multifunctional enzyme type 2 chr5 GO:0016491 Not Cancer Driver No 99 0.135 82 12 0.146 4
HSD17B6_ENST00000322165 HSD17B6 O14756 17-beta-hydroxysteroid dehydrogenase type 6 chr12 GO:0016491 Not Cancer Driver No 35 0.11 5 1 0.2 0
HSD17B7 HSD17B7 P56937 3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7 chr1 GO:0016491 Not Cancer Driver No 33 0.097 0 0 0.0 0
HSD17B8 HSD17B8 Q92506 (3R)-3-hydroxyacyl-CoA dehydrogenase chr6 GO:0016491 Not Cancer Driver No 20 0.077 26 1 0.038 0
HSD3B1 HSD3B1 P14060 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 chr1 GO:0016491 Not Cancer Driver No 69 0.185 25 3 0.12 0
HSD3B2_ENST00000369416 HSD3B2 P26439 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2 chr1 GO:0016491 Not Cancer Driver No 83 0.223 24 9 0.375 28
HSD3B7 HSD3B7 Q9H2F3 3 beta-hydroxysteroid dehydrogenase type 7 chr16 GO:0016491 Not Cancer Driver No 43 0.117 27 5 0.185 2
HSDL1 HSDL1 Q3SXM5 Inactive hydroxysteroid dehydrogenase-like protein 1 chr16 GO:0016491 Not Cancer Driver No 24 0.073 0 0 0.0 0
HSDL2 HSDL2 Q6YN16 Hydroxysteroid dehydrogenase-like protein 2 chr9 GO:0016491 Not Cancer Driver No 37 0.089 41 5 0.122 0
HTATIP2_ENST00000443524 HTATIP2 Q9BUP3 Oxidoreductase HTATIP2 chr11 GO:0016491 Not Cancer Driver No 22 0.091 14 0 0.0 0
IDH1 IDH1 O75874 Isocitrate dehydrogenase [NADP] cytoplasmic chr2 GO:0016491 Census, Compendium Yes 553 1.336 37 3 0.081 0
IDH2 IDH2 P48735 Isocitrate dehydrogenase [NADP], mitochondrial chr15 GO:0016491 Census, Compendium Yes 74 0.164 59 1 0.017 7
IDH3A IDH3A P50213 Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial chr15 GO:0016491 Not Cancer Driver No 41 0.112 47 11 0.234 0
IDH3B_ENST00000380843 IDH3B O43837 Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial chr20 GO:0016491 Not Cancer Driver No 32 0.083 49 3 0.061 1
IDH3G IDH3G P51553 Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial chrX GO:0016491 Not Cancer Driver No 48 0.122 77 9 0.117 0
IDO1_ENST00000522495 IDO1 P14902 Indoleamine 2,3-dioxygenase 1 chr8 GO:0016491 Not Cancer Driver No 82 0.203 41 8 0.195 0
IDO2 IDO2 Q6ZQW0 Indoleamine 2,3-dioxygenase 2 chr8 GO:0016491 Not Cancer Driver No 93 0.221 35 5 0.143 0
IFI30 IFI30 P13284 Gamma-interferon-inducible lysosomal thiol reductase chr19 GO:0016491 Not Cancer Driver No 22 0.088 16 2 0.125 0
IL4I1_ENST00000391826 IL4I1 Q96RQ9 L-amino-acid oxidase chr19 GO:0016491 Not Cancer Driver No 65 0.115 136 14 0.103 0
IMPDH1_ENST00000626419 IMPDH1 P20839 Inosine-5'-monophosphate dehydrogenase 1 chr7 GO:0016491 Not Cancer Driver No 75 0.146 13 1 0.077 7
IMPDH2 IMPDH2 P12268 Inosine-5'-monophosphate dehydrogenase 2 chr3 GO:0016491 Not Cancer Driver No 70 0.136 6 1 0.167 0
IPCEF1_ENST00000265198 IPCEF1 Q8WWN9 Interactor protein for cytohesin exchange factors 1 chr6 GO:0016491 Not Cancer Driver No 53 0.121 293 31 0.106 0
IVD IVD P26440 Isovaleryl-CoA dehydrogenase, mitochondrial chr15 GO:0016491 Not Cancer Driver No 46 0.108 8 0 0.0 14
IYD_ENST00000344419 IYD Q6PHW0 Iodotyrosine deiodinase 1 chr6 GO:0016491 Not Cancer Driver No 53 0.183 75 21 0.28 2
JARID2 JARID2 Q92833 Protein Jumonji chr6 GO:0016491 Not Cancer Driver No 190 0.152 724 113 0.156 0
JMJD4 JMJD4 Q9H9V9 2-oxoglutarate and iron-dependent oxygenase JMJD4 chr1 GO:0016491 Not Cancer Driver No 67 0.145 19 5 0.263 0
JMJD6_ENST00000397625 JMJD6 Q6NYC1 Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 chr17 GO:0016491 Not Cancer Driver No 51 0.127 133 21 0.158 0
JMJD7 JMJD7 P0C870 Bifunctional peptidase and (3S)-lysyl hydroxylase JMJD7 chr15 GO:0016491 Not Cancer Driver No 40 0.127 0 0 0.0 0
KCNAB1 KCNAB1 Q14722 Voltage-gated potassium channel subunit beta-1 chr3 GO:0016491 Not Cancer Driver No 89 0.212 83 23 0.277 0
KCNAB2_ENST00000378097 KCNAB2 Q13303 Voltage-gated potassium channel subunit beta-2 chr1 GO:0016491 Not Cancer Driver No 41 0.112 33 1 0.03 0
KCNAB3 KCNAB3 O43448 Voltage-gated potassium channel subunit beta-3 chr17 GO:0016491 Not Cancer Driver No 42 0.104 99 4 0.04 0
KDM1A_ENST00000356634 KDM1A O60341 Lysine-specific histone demethylase 1A chr1 GO:0016491 Not Cancer Driver No 67 0.079 291 28 0.096 3
KDM1B_ENST00000449850 KDM1B Q8NB78 Lysine-specific histone demethylase 1B chr6 GO:0016491 Not Cancer Driver No 81 0.099 74 11 0.149 0
KDM2A KDM2A Q9Y2K7 Lysine-specific demethylase 2A chr11 GO:0016491 Not Cancer Driver No 131 0.113 387 48 0.124 0
KDM2B KDM2B Q8NHM5 Lysine-specific demethylase 2B chr12 GO:0016491 Not Cancer Driver No 187 0.14 617 90 0.146 0
KDM3A_ENST00000312912 KDM3A Q9Y4C1 Lysine-specific demethylase 3A chr2 GO:0016491 Not Cancer Driver No 136 0.103 461 47 0.102 0
KDM3B KDM3B Q7LBC6 Lysine-specific demethylase 3B chr5 GO:0016491 Compendium Yes 221 0.125 943 114 0.121 7
KDM4A KDM4A O75164 Lysine-specific demethylase 4A chr1 GO:0016491 Not Cancer Driver No 122 0.115 337 44 0.131 0
KDM4B KDM4B O94953 Lysine-specific demethylase 4B chr19 GO:0016491 Not Cancer Driver No 133 0.121 429 49 0.114 3
KDM4C KDM4C Q9H3R0 Lysine-specific demethylase 4C chr9 GO:0016491 Not Cancer Driver No 124 0.117 309 40 0.129 0
KDM4D_ENST00000610872 KDM4D Q6B0I6 Lysine-specific demethylase 4D chr11 GO:0016491 Not Cancer Driver No 78 0.149 215 33 0.153 0
KDM4E KDM4E B2RXH2 Lysine-specific demethylase 4E chr11 GO:0016491 Not Cancer Driver No 43 0.085 188 10 0.053 0
KDM5A KDM5A P29375 Lysine-specific demethylase 5A chr12 GO:0016491 Census, Compendium Yes 220 0.13 503 66 0.131 0
KDM5B_ENST00000367265 KDM5B Q9UGL1 Lysine-specific demethylase 5B chr1 GO:0016491 Not Cancer Driver No 219 0.142 388 58 0.149 0
KDM5C KDM5C P41229 Lysine-specific demethylase 5C chrX GO:0016491 Census, Compendium Yes 167 0.107 499 46 0.092 10
KDM5D KDM5D Q9BY66 Lysine-specific demethylase 5D chrY GO:0016491 Not Cancer Driver No 50 0.032 406 11 0.027 0
KDM6A KDM6A O15550 Lysine-specific demethylase 6A chrX GO:0016491 Census, Compendium Yes 173 0.123 648 71 0.11 0
KDM6B_ENST00000448097 KDM6B O15054 Lysine-specific demethylase 6B chr17 GO:0016491 Not Cancer Driver No 189 0.115 1278 142 0.111 2
KDM7A KDM7A Q6ZMT4 Lysine-specific demethylase 7A chr7 GO:0016491 Not Cancer Driver No 112 0.119 444 54 0.122 0
KDM8_ENST00000286096 KDM8 Q8N371 Bifunctional peptidase and arginyl-hydroxylase JMJD5 chr16 GO:0016491 Not Cancer Driver No 52 0.125 29 6 0.207 0
KDSR KDSR Q06136 3-ketodihydrosphingosine reductase chr18 GO:0016491 Census Yes 31 0.093 35 4 0.114 1
KIAA1191_ENST00000510164 KIAA1191 Q96A73 Putative monooxygenase p33MONOX chr5 GO:0016491 Not Cancer Driver No 25 0.082 288 22 0.076 0
KMO KMO O15229 Kynurenine 3-monooxygenase chr1 GO:0016491 Not Cancer Driver No 77 0.158 0 0 0.0 0
L2HGDH_ENST00000421284 L2HGDH Q9H9P8 L-2-hydroxyglutarate dehydrogenase, mitochondrial chr14 GO:0016491 Not Cancer Driver No 52 0.112 0 0 0.0 8
LACC1 LACC1 Q8IV20 Purine nucleoside phosphorylase LACC1 chr13 GO:0016491 Not Cancer Driver No 50 0.116 4 0 0.0 1
LBR_ENST00000272163 LBR Q14739 Delta(14)-sterol reductase LBR chr1 GO:0016491 Not Cancer Driver No 95 0.154 130 15 0.115 5
LDHAL6A LDHAL6A Q6ZMR3 L-lactate dehydrogenase A-like 6A chr11 GO:0016491 Not Cancer Driver No 47 0.142 16 4 0.25 0
LDHAL6B LDHAL6B Q9BYZ2 L-lactate dehydrogenase A-like 6B chr15 GO:0016491 Not Cancer Driver No 54 0.142 17 2 0.118 0
LDHA_ENST00000422447 LDHA P00338 L-lactate dehydrogenase A chain chr11 GO:0016491 Not Cancer Driver No 40 0.12 9 0 0.0 0
LDHB_ENST00000350669 LDHB P07195 L-lactate dehydrogenase B chain chr12 GO:0016491 Not Cancer Driver No 47 0.141 15 2 0.133 11
LDHC LDHC P07864 L-lactate dehydrogenase C chain chr11 GO:0016491 Not Cancer Driver No 61 0.184 0 0 0.0 0
LDHD LDHD Q86WU2 Probable D-lactate dehydrogenase, mitochondrial chr16 GO:0016491 Not Cancer Driver No 55 0.108 48 6 0.125 2
LIPF_ENST00000238983 LIPF P07098 Gastric triacylglycerol lipase chr10 GO:0016491 Not Cancer Driver No 74 0.186 0 0 0.0 0
LOX LOX P28300 Protein-lysine 6-oxidase chr5 GO:0016491 Compendium Yes 44 0.106 172 11 0.064 4
LOXL1 LOXL1 Q08397 Lysyl oxidase homolog 1 chr15 GO:0016491 Not Cancer Driver No 49 0.085 337 14 0.042 0
LOXL2 LOXL2 Q9Y4K0 Lysyl oxidase homolog 2 chr8 GO:0016491 Not Cancer Driver No 134 0.173 39 4 0.103 0
LOXL3 LOXL3 P58215 Lysyl oxidase homolog 3 chr2 GO:0016491 Not Cancer Driver No 91 0.121 86 17 0.198 0
LOXL4 LOXL4 Q96JB6 Lysyl oxidase homolog 4 chr10 GO:0016491 Not Cancer Driver No 95 0.126 122 11 0.09 0
LPO LPO P22079 Lactoperoxidase chr17 GO:0016491 Not Cancer Driver No 127 0.178 99 17 0.172 0
LTC4S LTC4S Q16873 Leukotriene C4 synthase chr5 GO:0016491 Not Cancer Driver No 3 0.02 0 0 0.0 0
MAOA MAOA P21397 Amine oxidase [flavin-containing] A chrX GO:0016491 Not Cancer Driver No 61 0.116 23 4 0.174 0
MAOB MAOB P27338 Amine oxidase [flavin-containing] B chrX GO:0016491 Not Cancer Driver No 75 0.144 44 6 0.136 0
MARC1 MTARC1 Q5VT66 Mitochondrial amidoxime-reducing component 1 chr1 GO:0016491 Not Cancer Driver No 49 0.145 26 6 0.231 0
MARC2 MTARC2 Q969Z3 Mitochondrial amidoxime reducing component 2 chr1 GO:0016491 Not Cancer Driver No 33 0.099 4 0 0.0 0
MDH1B MDH1B Q5I0G3 Putative malate dehydrogenase 1B chr2 GO:0016491 Not Cancer Driver No 103 0.199 46 13 0.283 0
MDH1_ENST00000233114 MDH1 P40925 Malate dehydrogenase, cytoplasmic chr2 GO:0016491 Not Cancer Driver No 41 0.123 18 2 0.111 1
MDH2 MDH2 P40926 Malate dehydrogenase, mitochondrial chr7 GO:0016491 Not Cancer Driver No 39 0.115 8 1 0.125 3
ME1 ME1 P48163 NADP-dependent malic enzyme chr6 GO:0016491 Not Cancer Driver No 109 0.191 64 10 0.156 0
ME2 ME2 P23368 NAD-dependent malic enzyme, mitochondrial chr18 GO:0016491 Not Cancer Driver No 69 0.118 32 5 0.156 0
ME3_ENST00000393324 ME3 Q16798 NADP-dependent malic enzyme, mitochondrial chr11 GO:0016491 Not Cancer Driver No 105 0.174 45 9 0.2 0
MECR MECR Q9BV79 Enoyl-[acyl-carrier-protein] reductase, mitochondrial chr1 GO:0016491 Not Cancer Driver No 55 0.147 26 5 0.192 3
MGST1_ENST00000396210 MGST1 P10620 Microsomal glutathione S-transferase 1 chr12 GO:0016491 Not Cancer Driver No 26 0.168 0 0 0.0 0
MGST2 MGST2 Q99735 Microsomal glutathione S-transferase 2 chr4 GO:0016491 Not Cancer Driver No 11 0.075 0 0 0.0 0
MGST3 MGST3 O14880 Microsomal glutathione S-transferase 3 chr1 GO:0016491 Not Cancer Driver No 17 0.112 0 0 0.0 0
MICAL1_ENST00000358807 MICAL1 Q8TDZ2 [F-actin]-monooxygenase MICAL1 chr6 GO:0016491 Not Cancer Driver No 112 0.105 364 37 0.102 0
MICAL2_ENST00000646065 MICAL2 O94851 [F-actin]-monooxygenase MICAL2 chr11 GO:0016491 Not Cancer Driver No 297 0.152 1191 179 0.15 0
MIOX MIOX Q9UGB7 Inositol oxygenase chr22 GO:0016491 Not Cancer Driver No 48 0.168 21 4 0.19 0
MMACHC MMACHC Q9Y4U1 Cyanocobalamin reductase / alkylcobalamin dealkylase chr1 GO:0016491 Not Cancer Driver No 29 0.103 85 5 0.059 14
MOXD1 MOXD1 Q6UVY6 DBH-like monooxygenase protein 1 chr6 GO:0016491 Not Cancer Driver No 99 0.162 29 7 0.241 0
MPO MPO P05164 Myeloperoxidase chr17 GO:0016491 Not Cancer Driver No 149 0.2 52 12 0.231 3
MSMO1 MSMO1 Q15800 Methylsterol monooxygenase 1 chr4 GO:0016491 Not Cancer Driver No 42 0.143 4 0 0.0 2
MSRA MSRA Q9UJ68 Mitochondrial peptide methionine sulfoxide reductase chr8 GO:0016491 Not Cancer Driver No 39 0.166 81 14 0.173 0
MSRB1_ENST00000622125 MSRB1 Q9NZV6 Methionine-R-sulfoxide reductase B1 chr16 GO:0016491 Not Cancer Driver No 18 0.155 28 5 0.179 0
MSRB2 MSRB2 Q9Y3D2 Methionine-R-sulfoxide reductase B2, mitochondrial chr10 GO:0016491 Not Cancer Driver No 17 0.093 65 6 0.092 0
MSRB3 MSRB3 Q8IXL7 Methionine-R-sulfoxide reductase B3 chr12 GO:0016491 Not Cancer Driver No 49 0.255 42 14 0.333 1
MTHFD1 MTHFD1 P11586 C-1-tetrahydrofolate synthase, cytoplasmic chr14 GO:0016491 Not Cancer Driver No 103 0.11 129 11 0.085 6
MTHFD1L_ENST00000367321 MTHFD1L Q6UB35 Monofunctional C1-tetrahydrofolate synthase, mitochondrial chr6 GO:0016491 Not Cancer Driver No 117 0.12 139 11 0.079 0
MTHFD2 MTHFD2 P13995 Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial chr2 GO:0016491 Not Cancer Driver No 39 0.111 39 3 0.077 0
MTHFD2L MTHFD2L Q9H903 Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, mitochondrial chr4 GO:0016491 Not Cancer Driver No 45 0.13 59 6 0.102 0
MTHFR_ENST00000376590 MTHFR P42898 Methylenetetrahydrofolate reductase chr1 GO:0016491 Not Cancer Driver No 95 0.145 125 22 0.176 53
MTRR_ENST00000440940 MTRR Q9UBK8 Methionine synthase reductase chr5 GO:0016491 Not Cancer Driver No 101 0.145 84 13 0.155 5
NCF1 NCF1 P14598 Neutrophil cytosol factor 1 chr7 GO:0016491 Not Cancer Driver No 37 0.095 181 12 0.066 1
NCF2 NCF2 P19878 Neutrophil cytosol factor 2 chr1 GO:0016491 Not Cancer Driver No 97 0.184 183 34 0.186 14
NDOR1_ENST00000344894 NDOR1 Q9UHB4 NADPH-dependent diflavin oxidoreductase 1 chr9 GO:0016491 Not Cancer Driver No 60 0.101 67 7 0.104 0
NDUFA1 NDUFA1 O15239 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 chrX GO:0016491 Not Cancer Driver No 14 0.2 0 0 0.0 2
NDUFA10 NDUFA10 O95299 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial chr2 GO:0016491 Not Cancer Driver No 48 0.135 19 0 0.0 1
NDUFA12 NDUFA12 Q9UI09 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 chr12 GO:0016491 Not Cancer Driver No 18 0.124 31 6 0.194 0
NDUFA13 NDUFA13 Q9P0J0 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 chr19 GO:0016491 Not Cancer Driver No 29 0.201 24 4 0.167 1
NDUFA2 NDUFA2 O43678 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 chr5 GO:0016491 Not Cancer Driver No 10 0.101 0 0 0.0 0
NDUFA3 NDUFA3 O95167 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 chr19 GO:0016491 Not Cancer Driver No 7 0.083 27 4 0.148 0
NDUFA4 NDUFA4 O00483 Cytochrome c oxidase subunit NDUFA4 chr7 GO:0016491 Not Cancer Driver No 14 0.173 4 0 0.0 0
NDUFA5_ENST00000355749 NDUFA5 Q16718 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 chr7 GO:0016491 Not Cancer Driver No 10 0.086 10 1 0.1 0
NDUFA6_ENST00000602404 NDUFA6 P56556 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 chr22 GO:0016491 Not Cancer Driver No 10 0.078 14 2 0.143 1
NDUFA7 NDUFA7 O95182 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 chr19 GO:0016491 Not Cancer Driver No 16 0.142 103 13 0.126 0
NDUFA8 NDUFA8 P51970 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 chr9 GO:0016491 Not Cancer Driver No 25 0.145 33 1 0.03 2
NDUFA9 NDUFA9 Q16795 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial chr12 GO:0016491 Not Cancer Driver No 57 0.151 8 0 0.0 2
NDUFAF5 NDUFAF5 Q5TEU4 Arginine-hydroxylase NDUFAF5, mitochondrial chr20 GO:0016491 Not Cancer Driver No 47 0.136 69 15 0.217 3
NDUFB10 NDUFB10 O96000 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 chr16 GO:0016491 Not Cancer Driver No 19 0.11 33 1 0.03 1
NDUFB1_ENST00000605997 NDUFB1 O75438 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 chr14 GO:0016491 Not Cancer Driver No 5 0.086 0 0 0.0 0
NDUFB2_ENST00000247866 NDUFB2 O95178 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial chr7 GO:0016491 Not Cancer Driver No 13 0.124 26 3 0.115 0
NDUFB3 NDUFB3 O43676 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 chr2 GO:0016491 Not Cancer Driver No 15 0.153 17 1 0.059 1
NDUFB4 NDUFB4 O95168 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 chr3 GO:0016491 Not Cancer Driver No 13 0.101 20 1 0.05 0
NDUFB5 NDUFB5 O43674 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial chr3 GO:0016491 Not Cancer Driver No 28 0.148 9 1 0.111 0
NDUFB6 NDUFB6 O95139 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 chr9 GO:0016491 Not Cancer Driver No 24 0.188 20 3 0.15 0
NDUFB7 NDUFB7 P17568 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 chr19 GO:0016491 Not Cancer Driver No 17 0.124 65 6 0.092 0
NDUFB8 NDUFB8 O95169 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial chr10 GO:0016491 Not Cancer Driver No 28 0.151 64 11 0.172 3
NDUFB9 NDUFB9 Q9Y6M9 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 chr8 GO:0016491 Not Cancer Driver No 23 0.128 34 5 0.147 1
NDUFC1_ENST00000539387 NDUFC1 O43677 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial chr4 GO:0016491 Not Cancer Driver No 4 0.053 4 0 0.0 0
NDUFC2 NDUFC2 O95298 NADH dehydrogenase [ubiquinone] 1 subunit C2 chr11 GO:0016491 Not Cancer Driver No 15 0.126 4 0 0.0 1
NDUFS1_ENST00000449699 NDUFS1 P28331 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial chr2 GO:0016491 Not Cancer Driver No 81 0.111 40 3 0.075 2
NDUFS2 NDUFS2 O75306 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial chr1 GO:0016491 Not Cancer Driver No 58 0.125 49 5 0.102 4
NDUFS3 NDUFS3 O75489 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial chr11 GO:0016491 Not Cancer Driver No 34 0.129 26 3 0.115 2
NDUFS4 NDUFS4 O43181 NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial chr5 GO:0016491 Not Cancer Driver No 26 0.149 92 17 0.185 1
NDUFS5_ENST00000372967 NDUFS5 O43920 NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 chr1 GO:0016491 Not Cancer Driver No 15 0.142 31 3 0.097 0
NDUFS6 NDUFS6 O75380 NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial chr5 GO:0016491 Not Cancer Driver No 20 0.161 8 0 0.0 1
NDUFS7 NDUFS7 O75251 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial chr19 GO:0016491 Not Cancer Driver No 36 0.169 30 3 0.1 1
NDUFS8 NDUFS8 O00217 NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial chr11 GO:0016491 Not Cancer Driver No 27 0.129 37 2 0.054 3
NDUFV1 NDUFV1 P49821 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial chr11 GO:0016491 Not Cancer Driver No 66 0.142 57 9 0.158 3
NDUFV2 NDUFV2 P19404 NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial chr18 GO:0016491 Not Cancer Driver No 40 0.161 69 15 0.217 0
NDUFV3_ENST00000340344 NDUFV3 P56181 NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial chr21 GO:0016491 Not Cancer Driver No 5 0.046 95 4 0.042 0
NLRP11 NLRP11 P59045 NACHT, LRR and PYD domains-containing protein 11 chr19 GO:0016491 Not Cancer Driver No 229 0.222 25 2 0.08 0
NNT_ENST00000344920 NNT Q13423 NAD(P) transhydrogenase, mitochondrial chr5 GO:0016491 Not Cancer Driver No 129 0.119 47 6 0.128 11
NOS1_ENST00000317775 NOS1 P29475 Nitric oxide synthase, brain chr12 GO:0016491 Not Cancer Driver No 405 0.282 342 99 0.289 0
NOS2 NOS2 P35228 Nitric oxide synthase, inducible chr17 GO:0016491 Not Cancer Driver No 207 0.18 201 33 0.164 0
NOS3 NOS3 P29474 Nitric oxide synthase, endothelial chr7 GO:0016491 Not Cancer Driver No 168 0.14 347 38 0.11 0
NOX1 NOX1 Q9Y5S8 NADPH oxidase 1 chrX GO:0016491 Not Cancer Driver No 101 0.179 18 8 0.444 0
NOX3 NOX3 Q9HBY0 NADPH oxidase 3 chr6 GO:0016491 Not Cancer Driver No 118 0.208 3 0 0.0 0
NOX4 NOX4 Q9NPH5 NADPH oxidase 4 chr11 GO:0016491 Not Cancer Driver No 123 0.213 0 0 0.0 0
NOX5 NOX5 Q96PH1 NADPH oxidase 5 chr15 GO:0016491 Not Cancer Driver No 118 0.154 95 9 0.095 0
NOXRED1 NOXRED1 Q6NXP6 NADP-dependent oxidoreductase domain-containing protein 1 chr14 GO:0016491 Not Cancer Driver No 50 0.139 4 1 0.25 0
NQO1 NQO1 P15559 NAD(P)H dehydrogenase [quinone] 1 chr16 GO:0016491 Not Cancer Driver No 21 0.077 10 1 0.1 0
NQO2_ENST00000380430 NQO2 P16083 Ribosyldihydronicotinamide dehydrogenase [quinone] chr6 GO:0016491 Not Cancer Driver No 28 0.121 10 1 0.1 0
NSDHL NSDHL Q15738 Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating chrX GO:0016491 Not Cancer Driver No 60 0.161 39 6 0.154 3
NXN NXN Q6DKJ4 Nucleoredoxin chr17 GO:0016491 Not Cancer Driver No 58 0.133 37 2 0.054 0
OGDH OGDH Q02218 2-oxoglutarate dehydrogenase complex component E1 chr7 GO:0016491 Not Cancer Driver No 150 0.147 106 19 0.179 0
OGDHL OGDHL Q9ULD0 2-oxoglutarate dehydrogenase-like, mitochondrial chr10 GO:0016491 Not Cancer Driver No 262 0.259 128 38 0.297 0
OGFOD1 OGFOD1 Q8N543 Prolyl 3-hydroxylase OGFOD1 chr16 GO:0016491 Not Cancer Driver No 44 0.081 156 6 0.038 0
OXNAD1_ENST00000605932 OXNAD1 Q96HP4 Oxidoreductase NAD-binding domain-containing protein 1 chr3 GO:0016491 Not Cancer Driver No 48 0.154 13 2 0.154 0
OXR1 OXR1 Q8N573 Oxidation resistance protein 1 chr8 GO:0016491 Not Cancer Driver No 126 0.144 544 76 0.14 0
P3H1_ENST00000296388 P3H1 Q32P28 Prolyl 3-hydroxylase 1 chr1 GO:0016491 Not Cancer Driver No 91 0.124 177 18 0.102 0
P3H2 P3H2 Q8IVL5 Prolyl 3-hydroxylase 2 chr3 GO:0016491 Not Cancer Driver No 131 0.185 160 24 0.15 1
P3H3 P3H3 Q8IVL6 Prolyl 3-hydroxylase 3 chr12 GO:0016491 Not Cancer Driver No 84 0.114 307 40 0.13 0
P4HA1_ENST00000394890 P4HA1 P13674 Prolyl 4-hydroxylase subunit alpha-1 chr10 GO:0016491 Not Cancer Driver No 65 0.122 54 8 0.148 0
P4HA2_ENST00000379104 P4HA2 O15460 Prolyl 4-hydroxylase subunit alpha-2 chr5 GO:0016491 Not Cancer Driver No 66 0.123 82 12 0.146 2
P4HA3_ENST00000331597 P4HA3 Q7Z4N8 Prolyl 4-hydroxylase subunit alpha-3 chr11 GO:0016491 Not Cancer Driver No 70 0.129 17 2 0.118 0
P4HB P4HB P07237 Protein disulfide-isomerase chr17 GO:0016491 Not Cancer Driver No 61 0.12 79 15 0.19 1
P4HTM_ENST00000383729 P4HTM Q9NXG6 Transmembrane prolyl 4-hydroxylase chr3 GO:0016491 Not Cancer Driver No 76 0.151 144 20 0.139 1
PAH PAH P00439 Phenylalanine-4-hydroxylase chr12 GO:0016491 Not Cancer Driver No 133 0.294 13 4 0.308 222
PAM_ENST00000438793 PAM P19021 Peptidyl-glycine alpha-amidating monooxygenase chr5 GO:0016491 Not Cancer Driver No 129 0.133 254 37 0.146 0
PAOX PAOX Q6QHF9 Peroxisomal N(1)-acetyl-spermine/spermidine oxidase chr10 GO:0016491 Not Cancer Driver No 70 0.137 29 0 0.0 0
PARK7_ENST00000377488 PARK7 Q99497 Parkinson disease protein 7 chr1 GO:0016491 Not Cancer Driver No 11 0.058 30 0 0.0 5
PCBD1 PCBD1 P61457 Pterin-4-alpha-carbinolamine dehydratase chr10 GO:0016491 Not Cancer Driver No 8 0.077 7 0 0.0 3
PCBD2_ENST00000254908 PCBD2 Q9H0N5 Pterin-4-alpha-carbinolamine dehydratase 2 chr5 GO:0016491 Not Cancer Driver No 6 0.046 3 0 0.0 0
PCYOX1 PCYOX1 Q9UHG3 Prenylcysteine oxidase 1 chr2 GO:0016491 Not Cancer Driver No 60 0.119 9 1 0.111 0
PCYOX1L PCYOX1L Q8NBM8 Prenylcysteine oxidase-like chr5 GO:0016491 Not Cancer Driver No 61 0.123 0 0 0.0 0
PDHA1_ENST00000422285 PDHA1 P08559 Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial chrX GO:0016491 Not Cancer Driver No 70 0.179 43 6 0.14 20
PDHA2 PDHA2 P29803 Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial chr4 GO:0016491 Not Cancer Driver No 163 0.42 41 17 0.415 0
PDHB PDHB P11177 Pyruvate dehydrogenase E1 component subunit beta, mitochondrial chr3 GO:0016491 Not Cancer Driver No 32 0.089 4 0 0.0 2
PDHX PDHX O00330 Pyruvate dehydrogenase protein X component, mitochondrial chr11 GO:0016491 Not Cancer Driver No 62 0.124 179 28 0.156 0
PDIA2 PDIA2 Q13087 Protein disulfide-isomerase A2 chr16 GO:0016491 Not Cancer Driver No 70 0.133 80 12 0.15 0
PDIA3 PDIA3 P30101 Protein disulfide-isomerase A3 chr15 GO:0016491 Not Cancer Driver No 57 0.113 98 11 0.112 0
PDIA4 PDIA4 P13667 Protein disulfide-isomerase A4 chr7 GO:0016491 Not Cancer Driver No 81 0.126 147 22 0.15 0
PDIA5 PDIA5 Q14554 Protein disulfide-isomerase A5 chr3 GO:0016491 Not Cancer Driver No 73 0.141 79 9 0.114 0
PDIA6_ENST00000272227 PDIA6 Q15084 Protein disulfide-isomerase A6 chr2 GO:0016491 Not Cancer Driver No 55 0.125 82 11 0.134 0
PDPR PDPR Q8NCN5 Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial chr16 GO:0016491 Compendium Yes 142 0.162 35 4 0.114 0
PECR PECR Q9BY49 Peroxisomal trans-2-enoyl-CoA reductase chr2 GO:0016491 Not Cancer Driver No 29 0.096 8 0 0.0 0
PGD PGD P52209 6-phosphogluconate dehydrogenase, decarboxylating chr1 GO:0016491 Not Cancer Driver No 73 0.151 19 3 0.158 0
PGK1 PGK1 P00558 Phosphoglycerate kinase 1 chrX GO:0016491 Not Cancer Driver No 61 0.146 40 5 0.125 9
PHF2 PHF2 O75151 Lysine-specific demethylase PHF2 chr9 GO:0016491 Not Cancer Driver No 131 0.12 725 80 0.11 0
PHF8 PHF8 Q9UPP1 Histone lysine demethylase PHF8 chrX GO:0016491 Not Cancer Driver No 154 0.145 603 93 0.154 1
PHGDH_ENST00000641023 PHGDH O43175 D-3-phosphoglycerate dehydrogenase chr1 GO:0016491 Not Cancer Driver No 51 0.096 38 4 0.105 8
PHYH PHYH O14832 Phytanoyl-CoA dioxygenase, peroxisomal chr10 GO:0016491 Not Cancer Driver No 54 0.16 40 4 0.1 14
PIPOX PIPOX Q9P0Z9 Peroxisomal sarcosine oxidase chr17 GO:0016491 Not Cancer Driver No 52 0.133 21 3 0.143 0
PIR_ENST00000380420 PIR O00625 Pirin chrX GO:0016491 Not Cancer Driver No 29 0.1 185 16 0.086 0
PLOD1 PLOD1 Q02809 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 chr1 GO:0016491 Not Cancer Driver No 86 0.118 12 0 0.0 5
PLOD2_ENST00000360060 PLOD2 O00469 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 chr3 GO:0016491 Not Cancer Driver No 109 0.148 17 3 0.176 4
PLOD3 PLOD3 O60568 Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 chr7 GO:0016491 Not Cancer Driver No 108 0.146 65 8 0.123 1
PNPO PNPO Q9NVS9 Pyridoxine-5'-phosphate oxidase chr17 GO:0016491 Not Cancer Driver No 23 0.088 62 8 0.129 3
POR POR P16435 NADPH--cytochrome P450 reductase chr7 GO:0016491 Not Cancer Driver No 62 0.092 93 4 0.043 9
PPOX PPOX P50336 Protoporphyrinogen oxidase chr1 GO:0016491 Not Cancer Driver No 48 0.101 34 6 0.176 56
PRDX1_ENST00000319248 PRDX1 Q06830 Peroxiredoxin-1 chr1 GO:0016491 Not Cancer Driver No 22 0.111 40 5 0.125 0
PRDX2 PRDX2 P32119 Peroxiredoxin-2 chr19 GO:0016491 Not Cancer Driver No 24 0.121 30 4 0.133 0
PRDX3 PRDX3 P30048 Thioredoxin-dependent peroxide reductase, mitochondrial chr10 GO:0016491 Not Cancer Driver No 23 0.09 23 3 0.13 0
PRDX4 PRDX4 Q13162 Peroxiredoxin-4 chrX GO:0016491 Not Cancer Driver No 36 0.133 29 2 0.069 0
PRDX5 PRDX5 P30044 Peroxiredoxin-5, mitochondrial chr11 GO:0016491 Not Cancer Driver No 22 0.103 0 0 0.0 0
PRDX6 PRDX6 P30041 Peroxiredoxin-6 chr1 GO:0016491 Not Cancer Driver No 46 0.205 13 4 0.308 0
PRODH2 PRODH2 Q9UF12 Hydroxyproline dehydrogenase chr19 GO:0016491 Not Cancer Driver No 96 0.179 51 7 0.137 0
PRODH_ENST00000610940 PRODH O43272 Proline dehydrogenase 1, mitochondrial chr22 GO:0016491 Not Cancer Driver No 62 0.103 67 8 0.119 16
PTGES PTGES O14684 Prostaglandin E synthase chr9 GO:0016491 Not Cancer Driver No 10 0.066 0 0 0.0 0
PTGES2 PTGES2 Q9H7Z7 Prostaglandin E synthase 2 chr9 GO:0016491 Not Cancer Driver No 30 0.08 30 1 0.033 0
PTGR1_ENST00000309195 PTGR1 Q14914 Prostaglandin reductase 1 chr9 GO:0016491 Not Cancer Driver No 40 0.122 12 1 0.083 0
PTGR2 PTGR2 Q8N8N7 Prostaglandin reductase 2 chr14 GO:0016491 Not Cancer Driver No 26 0.074 22 2 0.091 0
PTGS1 PTGS1 P23219 Prostaglandin G/H synthase 1 chr9 GO:0016491 Not Cancer Driver No 123 0.205 28 3 0.107 0
PTGS2 PTGS2 P35354 Prostaglandin G/H synthase 2 chr1 GO:0016491 Not Cancer Driver No 105 0.174 30 5 0.167 0
PXDN PXDN Q92626 Peroxidasin homolog chr2 GO:0016491 Not Cancer Driver No 332 0.224 307 77 0.251 1
PXDNL PXDNL A1KZ92 Probable oxidoreductase PXDNL chr8 GO:0016491 Not Cancer Driver No 554 0.379 397 171 0.431 0
PYCR1_ENST00000329875 PYCR1 P32322 Pyrroline-5-carboxylate reductase 1, mitochondrial chr17 GO:0016491 Not Cancer Driver No 31 0.097 67 10 0.149 9
PYCR2 PYCR2 Q96C36 Pyrroline-5-carboxylate reductase 2 chr1 GO:0016491 Not Cancer Driver No 31 0.097 41 3 0.073 2
PYCR3_ENST00000495276 PYCR3 Q53H96 Pyrroline-5-carboxylate reductase 3 chr8 GO:0016491 Not Cancer Driver No 21 0.077 11 0 0.0 0
PYROXD1 PYROXD1 Q8WU10 Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1 chr12 GO:0016491 Not Cancer Driver No 54 0.108 34 2 0.059 2
PYROXD2 PYROXD2 Q8N2H3 Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2 chr10 GO:0016491 Not Cancer Driver No 60 0.103 34 1 0.029 0
QDPR QDPR P09417 Dihydropteridine reductase chr4 GO:0016491 Not Cancer Driver No 41 0.168 25 3 0.12 16
QSOX1 QSOX1 O00391 Sulfhydryl oxidase 1 chr1 GO:0016491 Not Cancer Driver No 93 0.124 189 22 0.116 0
QSOX2 QSOX2 Q6ZRP7 Sulfhydryl oxidase 2 chr9 GO:0016491 Not Cancer Driver No 87 0.125 151 16 0.106 0
RDH10 RDH10 Q8IZV5 Retinol dehydrogenase 10 chr8 GO:0016491 Not Cancer Driver No 33 0.097 8 0 0.0 0
RDH11 RDH11 Q8TC12 Retinol dehydrogenase 11 chr14 GO:0016491 Not Cancer Driver No 25 0.079 2 0 0.0 0
RDH12_ENST00000267502 RDH12 Q96NR8 Retinol dehydrogenase 12 chr14 GO:0016491 Not Cancer Driver No 41 0.13 0 0 0.0 10
RDH13 RDH13 Q8NBN7 Retinol dehydrogenase 13 chr19 GO:0016491 Not Cancer Driver No 42 0.127 48 7 0.146 0
RDH14 RDH14 Q9HBH5 Retinol dehydrogenase 14 chr2 GO:0016491 Not Cancer Driver No 22 0.065 21 0 0.0 0
RDH16 RDH16 O75452 Retinol dehydrogenase 16 chr12 GO:0016491 Not Cancer Driver No 46 0.145 0 0 0.0 0
RDH5_ENST00000548082 RDH5 Q92781 Retinol dehydrogenase 5 chr12 GO:0016491 Not Cancer Driver No 39 0.123 0 0 0.0 18
RETSAT RETSAT Q6NUM9 All-trans-retinol 13,14-reductase chr2 GO:0016491 Not Cancer Driver No 98 0.161 25 5 0.2 0
RIOX1 RIOX1 Q9H6W3 Ribosomal oxygenase 1 chr14 GO:0016491 Not Cancer Driver No 52 0.081 215 15 0.07 0
RIOX2_ENST00000394198 RIOX2 Q8IUF8 Ribosomal oxygenase 2 chr3 GO:0016491 Not Cancer Driver No 49 0.105 74 10 0.135 0
RNLS RNLS Q5VYX0 Renalase chr10 GO:0016491 Not Cancer Driver No 42 0.123 15 1 0.067 0
RRM1 RRM1 P23921 Ribonucleoside-diphosphate reductase large subunit chr11 GO:0016491 Not Cancer Driver No 74 0.093 41 7 0.171 0
RRM2B RRM2B Q7LG56 Ribonucleoside-diphosphate reductase subunit M2 B chr8 GO:0016491 Not Cancer Driver No 46 0.131 32 5 0.156 9
RRM2_ENST00000641198 RRM2 P31350 Ribonucleoside-diphosphate reductase subunit M2 chr2 GO:0016491 Not Cancer Driver No 40 0.103 48 0 0.0 0
RSAD1 RSAD1 Q9HA92 Radical S-adenosyl methionine domain-containing protein 1, mitochondrial chr17 GO:0016491 Not Cancer Driver No 68 0.154 88 13 0.148 0
RTN4IP1 RTN4IP1 Q8WWV3 Reticulon-4-interacting protein 1, mitochondrial chr6 GO:0016491 Not Cancer Driver No 60 0.152 15 2 0.133 1
SARDH_ENST00000439388 SARDH Q9UL12 Sarcosine dehydrogenase, mitochondrial chr9 GO:0016491 Not Cancer Driver No 144 0.157 132 24 0.182 2
SC5D_ENST00000392789 SC5D O75845 Lathosterol oxidase chr11 GO:0016491 Not Cancer Driver No 43 0.144 21 3 0.143 3
SCCPDH SCCPDH Q8NBX0 Saccharopine dehydrogenase-like oxidoreductase chr1 GO:0016491 Not Cancer Driver No 56 0.131 26 1 0.038 0
SCD SCD O00767 Stearoyl-CoA desaturase chr10 GO:0016491 Not Cancer Driver No 36 0.1 18 0 0.0 0
SCD5 SCD5 Q86SK9 Stearoyl-CoA desaturase 5 chr4 GO:0016491 Not Cancer Driver No 43 0.13 42 8 0.19 0
SCO2_ENST00000395693 SCO2 O43819 Protein SCO2 homolog, mitochondrial chr22 GO:0016491 Not Cancer Driver No 31 0.117 51 8 0.157 8
SDHA SDHA P31040 Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial chr5 GO:0016491 Census Yes 115 0.173 71 13 0.183 7
SDHB SDHB P21912 Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial chr1 GO:0016491 Census Yes 37 0.132 17 3 0.176 23
SDHC SDHC Q99643 Succinate dehydrogenase cytochrome b560 subunit, mitochondrial chr1 GO:0016491 Census Yes 16 0.095 0 0 0.0 0
SDR16C5_ENST00000303749 SDR16C5 Q8N3Y7 Epidermal retinol dehydrogenase 2 chr8 GO:0016491 Not Cancer Driver No 81 0.262 4 0 0.0 0
SDR39U1 SDR39U1 Q9NRG7 Epimerase family protein SDR39U1 chr14 GO:0016491 Not Cancer Driver No 29 0.099 18 3 0.167 0
SDR42E1 SDR42E1 Q8WUS8 Short-chain dehydrogenase/reductase family 42E member 1 chr16 GO:0016491 Not Cancer Driver No 63 0.16 26 6 0.231 0
SDR9C7 SDR9C7 Q8NEX9 Short-chain dehydrogenase/reductase family 9C member 7 chr12 GO:0016491 Not Cancer Driver No 51 0.163 3 1 0.333 2
SELENBP1_ENST00000368868 SELENBP1 Q13228 Methanethiol oxidase chr1 GO:0016491 Not Cancer Driver No 67 0.142 32 5 0.156 2
SELENOF_ENST00000616787 SELENOF O60613 Selenoprotein F chr1 GO:0016491 Not Cancer Driver No 7 0.042 0 0 0.0 0
SELENOM_ENST00000611680 SELENOM Q8WWX9 Selenoprotein M chr22 GO:0016491 Not Cancer Driver No 10 0.069 21 2 0.095 0
SELENON SELENON Q9NZV5 Selenoprotein N chr1 GO:0016491 Not Cancer Driver No 53 0.09 93 5 0.054 11
SELENOT SELENOT P62341 Thioredoxin reductase-like selenoprotein T chr3 GO:0016491 Not Cancer Driver No 25 0.128 0 0 0.0 0
SESN2 SESN2 P58004 Sestrin-2 chr1 GO:0016491 Not Cancer Driver No 74 0.154 147 26 0.177 0
SLC27A5 SLC27A5 Q9Y2P5 Bile acyl-CoA synthetase chr19 GO:0016491 Not Cancer Driver No 107 0.155 7 2 0.286 0
SMOX_ENST00000305958 SMOX Q9NWM0 Spermine oxidase chr20 GO:0016491 Not Cancer Driver No 79 0.142 164 23 0.14 0
SNCA_ENST00000506244 SNCA P37840 Alpha-synuclein chr4 GO:0016491 Not Cancer Driver No 21 0.15 107 13 0.121 5
SOD1 SOD1 P00441 Superoxide dismutase [Cu-Zn] chr21 GO:0016491 Not Cancer Driver No 16 0.104 93 9 0.097 79
SOD2_ENST00000367055 SOD2 P04179 Superoxide dismutase [Mn], mitochondrial chr6 GO:0016491 Not Cancer Driver No 32 0.144 25 5 0.2 0
SOD3 SOD3 P08294 Extracellular superoxide dismutase [Cu-Zn] chr4 GO:0016491 Not Cancer Driver No 22 0.092 123 14 0.114 0
SORD SORD Q00796 Sorbitol dehydrogenase chr15 GO:0016491 Not Cancer Driver No 29 0.081 41 7 0.171 3
SPR SPR P35270 Sepiapterin reductase chr2 GO:0016491 Not Cancer Driver No 23 0.088 19 4 0.211 2
SQLE SQLE Q14534 Squalene monooxygenase chr8 GO:0016491 Not Cancer Driver No 54 0.094 40 5 0.125 0
SQOR_ENST00000568606 SQOR Q9Y6N5 Sulfide:quinone oxidoreductase, mitochondrial chr15 GO:0016491 Not Cancer Driver No 54 0.12 41 8 0.195 1
SRD5A1 SRD5A1 P18405 3-oxo-5-alpha-steroid 4-dehydrogenase 1 chr5 GO:0016491 Not Cancer Driver No 35 0.135 0 0 0.0 0
SRD5A2 SRD5A2 P31213 3-oxo-5-alpha-steroid 4-dehydrogenase 2 chr2 GO:0016491 Not Cancer Driver No 48 0.189 0 0 0.0 21
SRD5A3 SRD5A3 Q9H8P0 Polyprenol reductase chr4 GO:0016491 Not Cancer Driver No 35 0.11 0 0 0.0 0
SRXN1 SRXN1 Q9BYN0 Sulfiredoxin-1 chr20 GO:0016491 Not Cancer Driver No 15 0.109 48 2 0.042 0
STAB1 STAB1 Q9NY15 Stabilin-1 chr3 GO:0016491 Not Cancer Driver No 341 0.133 91 13 0.143 0
STAB2 STAB2 Q8WWQ8 Stabilin-2 chr12 GO:0016491 Not Cancer Driver No 482 0.189 101 16 0.158 0
STEAP1 STEAP1 Q9UHE8 Metalloreductase STEAP1 chr7 GO:0016491 Not Cancer Driver No 45 0.133 26 3 0.115 0
STEAP2 STEAP2 Q8NFT2 Metalloreductase STEAP2 chr7 GO:0016491 Not Cancer Driver No 68 0.139 1 0 0.0 0
STEAP3_ENST00000393107 STEAP3 Q658P3 Metalloreductase STEAP3 chr2 GO:0016491 Not Cancer Driver No 82 0.168 30 2 0.067 0
STEAP4 STEAP4 Q687X5 Metalloreductase STEAP4 chr7 GO:0016491 Not Cancer Driver No 97 0.211 0 0 0.0 0
SUMF1 SUMF1 Q8NBK3 Formylglycine-generating enzyme chr3 GO:0016491 Not Cancer Driver No 41 0.11 141 15 0.106 16
SUOX_ENST00000356124 SUOX P51687 Sulfite oxidase, mitochondrial chr12 GO:0016491 Not Cancer Driver No 68 0.125 184 32 0.174 11
SURF1 SURF1 Q15526 Surfeit locus protein 1 chr9 GO:0016491 Not Cancer Driver No 17 0.057 82 6 0.073 11
TBXAS1_ENST00000448866 TBXAS1 P24557 Thromboxane-A synthase chr7 GO:0016491 Not Cancer Driver No 116 0.218 44 8 0.182 4
TDO2 TDO2 P48775 Tryptophan 2,3-dioxygenase chr4 GO:0016491 Not Cancer Driver No 64 0.158 31 9 0.29 1
TECR TECR Q9NZ01 Very-long-chain enoyl-CoA reductase chr19 GO:0016491 Not Cancer Driver No 41 0.133 0 0 0.0 1
TECRL TECRL Q5HYJ1 Trans-2,3-enoyl-CoA reductase-like chr4 GO:0016491 Not Cancer Driver No 147 0.405 6 4 0.667 0
TET1 TET1 Q8NFU7 Methylcytosine dioxygenase TET1 chr10 GO:0016491 Census, Compendium Yes 316 0.148 1551 234 0.151 0
TET2 TET2 Q6N021 Methylcytosine dioxygenase TET2 chr4 GO:0016491 Census, Compendium Yes 191 0.095 1663 176 0.106 1
TET3 TET3 O43151 Methylcytosine dioxygenase TET3 chr2 GO:0016491 Not Cancer Driver No 208 0.116 1272 152 0.119 6
TH TH P07101 Tyrosine 3-monooxygenase chr11 GO:0016491 Not Cancer Driver No 61 0.116 149 21 0.141 38
TM7SF2 TM7SF2 O76062 Delta(14)-sterol reductase TM7SF2 chr11 GO:0016491 Not Cancer Driver No 51 0.122 15 1 0.067 0
TMEM189 PEDS1 A5PLL7 Plasmanylethanolamine desaturase chr20 GO:0016491 Not Cancer Driver No 33 0.122 3 0 0.0 0
TMLHE TMLHE Q9NVH6 Trimethyllysine dioxygenase, mitochondrial chrX GO:0016491 Not Cancer Driver No 49 0.116 4 0 0.0 1
TMX3 TMX3 Q96JJ7 Protein disulfide-isomerase TMX3 chr18 GO:0016491 Not Cancer Driver No 50 0.11 49 9 0.184 0
TP53I3 TP53I3 Q53FA7 Quinone oxidoreductase PIG3 chr2 GO:0016491 Not Cancer Driver No 30 0.09 40 7 0.175 0
TPH1 TPH1 P17752 Tryptophan 5-hydroxylase 1 chr11 GO:0016491 Not Cancer Driver No 80 0.18 14 3 0.214 0
TPH2 TPH2 Q8IWU9 Tryptophan 5-hydroxylase 2 chr12 GO:0016491 Not Cancer Driver No 118 0.241 55 17 0.309 1
TPO TPO P07202 Thyroid peroxidase chr2 GO:0016491 Not Cancer Driver No 326 0.349 163 69 0.423 24
TSTA3_ENST00000529064 GFUS Q13630 GDP-L-fucose synthase chr8 GO:0016491 Not Cancer Driver No 38 0.118 19 2 0.105 0
TXN TXN P10599 Thioredoxin chr9 GO:0016491 Not Cancer Driver No 6 0.057 0 0 0.0 0
TXN2_ENST00000403313 TXN2 Q99757 Thioredoxin, mitochondrial chr22 GO:0016491 Not Cancer Driver No 22 0.133 34 4 0.118 0
TXNDC12 TXNDC12 O95881 Thioredoxin domain-containing protein 12 chr1 GO:0016491 Not Cancer Driver No 21 0.122 44 6 0.136 0
TXNDC17 TXNDC17 Q9BRA2 Thioredoxin domain-containing protein 17 chr17 GO:0016491 Not Cancer Driver No 8 0.065 0 0 0.0 0
TXNDC2 TXNDC2 Q86VQ3 Thioredoxin domain-containing protein 2 chr18 GO:0016491 Not Cancer Driver No 116 0.21 443 95 0.214 0
TXNDC8_ENST00000374511 TXNDC8 Q6A555 Thioredoxin domain-containing protein 8 chr9 GO:0016491 Not Cancer Driver No 19 0.15 0 0 0.0 0
TXNRD1 TXNRD1 Q16881 Thioredoxin reductase 1, cytoplasmic chr12 GO:0016491 Not Cancer Driver No 85 0.131 67 9 0.134 0
TXNRD2 TXNRD2 Q9NNW7 Thioredoxin reductase 2, mitochondrial chr22 GO:0016491 Not Cancer Driver No 70 0.134 46 6 0.13 0
TXNRD3_ENST00000640433 TXNRD3 Q86VQ6 Thioredoxin reductase 3 chr3 GO:0016491 Not Cancer Driver No 2 0.003 66 0 0.0 0
TYR TYR P14679 Tyrosinase chr11 GO:0016491 Not Cancer Driver No 156 0.295 52 15 0.288 111
TYRP1 TYRP1 P17643 5,6-dihydroxyindole-2-carboxylic acid oxidase chr9 GO:0016491 Not Cancer Driver No 81 0.151 87 13 0.149 2
TYW5 TYW5 A2RUC4 tRNA wybutosine-synthesizing protein 5 chr2 GO:0016491 Not Cancer Driver No 32 0.102 11 1 0.091 0
UGDH_ENST00000506179 UGDH O60701 UDP-glucose 6-dehydrogenase chr4 GO:0016491 Not Cancer Driver No 54 0.109 39 4 0.103 5
UQCRFS1 UQCRFS1 P47985 Cytochrome b-c1 complex subunit Rieske, mitochondrial chr19 GO:0016491 Not Cancer Driver No 43 0.157 47 4 0.085 1
UTY_ENST00000331397 UTY O14607 Histone demethylase UTY chrY GO:0016491 Not Cancer Driver No 38 0.028 564 21 0.037 0
VAT1 VAT1 Q99536 Synaptic vesicle membrane protein VAT-1 homolog chr17 GO:0016491 Not Cancer Driver No 39 0.099 83 10 0.12 0
VAT1L VAT1L Q9HCJ6 Synaptic vesicle membrane protein VAT-1 homolog-like chr16 GO:0016491 Not Cancer Driver No 98 0.234 82 19 0.232 0
VCAM1 VCAM1 P19320 Vascular cell adhesion protein 1 chr1 GO:0016491 Not Cancer Driver No 188 0.254 110 28 0.255 0
VKORC1 VKORC1 Q9BQB6 Vitamin K epoxide reductase complex subunit 1 chr16 GO:0016491 Not Cancer Driver No 14 0.086 3 0 0.0 19
VKORC1L1_ENST00000360768 VKORC1L1 Q8N0U8 Vitamin K epoxide reductase complex subunit 1-like protein 1 chr7 GO:0016491 Not Cancer Driver No 20 0.114 0 0 0.0 0
WDR93 WDR93 Q6P2C0 WD repeat-containing protein 93 chr15 GO:0016491 Not Cancer Driver No 88 0.128 97 14 0.144 0
WWOX WWOX Q9NZC7 WW domain-containing oxidoreductase chr16 GO:0016491 Not Cancer Driver No 79 0.191 108 9 0.083 3
XDH XDH P47989 Xanthine dehydrogenase/oxidase chr2 GO:0016491 Not Cancer Driver No 279 0.209 134 24 0.179 1
ZADH2 PTGR3 Q8N4Q0 Prostaglandin reductase 3 chr18 GO:0016491 Not Cancer Driver No 42 0.111 0 0 0.0 0