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Total number of protein in "GO:0016310" GO term:  268

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
AATK AATK Q6ZMQ8 Serine/threonine-protein kinase LMTK1 chr17 GO:0016310 Not Cancer Driver No 108 0.079 912 75 0.082 0
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0016310 Census, Compendium Yes 139 0.123 604 73 0.121 2
ACVR1_ENST00000434821 ACVR1 Q04771 Activin receptor type-1 chr2 GO:0016310 Census, Compendium Yes 78 0.153 21 8 0.381 8
ADK ADK P55263 Adenosine kinase chr10 GO:0016310 Not Cancer Driver No 29 0.08 33 2 0.061 3
ADPGK ADPGK Q9BRR6 ADP-dependent glucokinase chr15 GO:0016310 Not Cancer Driver No 38 0.076 24 0 0.0 0
AGK AGK Q53H12 Acylglycerol kinase, mitochondrial chr7 GO:0016310 Not Cancer Driver No 71 0.168 77 6 0.078 0
AK2 AK2 P54819 Adenylate kinase 2, mitochondrial chr1 GO:0016310 Not Cancer Driver No 23 0.096 76 12 0.158 2
AK3 AK3 Q9UIJ7 GTP:AMP phosphotransferase AK3, mitochondrial chr9 GO:0016310 Not Cancer Driver No 23 0.101 33 3 0.091 0
AK6 AK6 Q9Y3D8 Adenylate kinase isoenzyme 6 chr5 GO:0016310 Not Cancer Driver No 6 0.035 13 0 0.0 0
AK9 AK9 Q5TCS8 Adenylate kinase 9 chr6 GO:0016310 Not Cancer Driver No 235 0.123 589 58 0.098 0
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:0016310 Census, Compendium Yes 108 0.225 158 24 0.152 4
ALDH18A1 ALDH18A1 P54886 Delta-1-pyrroline-5-carboxylate synthase chr10 GO:0016310 Not Cancer Driver No 94 0.118 86 13 0.151 15
ALK ALK Q9UM73 ALK tyrosine kinase receptor chr2 GO:0016310 Census, Compendium Yes 303 0.187 575 114 0.198 16
AMH AMH P03971 Muellerian-inhibiting factor chr19 GO:0016310 Not Cancer Driver No 19 0.034 207 4 0.019 9
AMHR2 AMHR2 Q16671 Anti-Muellerian hormone type-2 receptor chr12 GO:0016310 Not Cancer Driver No 77 0.134 117 7 0.06 8
ATM_ENST00000452508 ATM Q13315 Serine-protein kinase ATM chr11 GO:0016310 Census, Compendium Yes 469 0.153 225 39 0.173 41
ATP13A2 ATP13A2 Q9NQ11 Polyamine-transporting ATPase 13A2 chr1 GO:0016310 Not Cancer Driver No 152 0.129 121 10 0.083 9
AURKA_ENST00000395915 AURKA O14965 Aurora kinase A chr20 GO:0016310 Not Cancer Driver No 36 0.089 178 21 0.118 0
AURKB_ENST00000585124 AURKB Q96GD4 Aurora kinase B chr17 GO:0016310 Not Cancer Driver No 51 0.148 63 8 0.127 0
AURKC AURKC Q9UQB9 Aurora kinase C chr19 GO:0016310 Not Cancer Driver No 70 0.227 43 5 0.116 0
BAZ1B_ENST00000404251 BAZ1B Q9UIG0 Tyrosine-protein kinase BAZ1B chr7 GO:0016310 Not Cancer Driver No 153 0.103 840 87 0.104 0
BCKDK BCKDK O14874 [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial chr16 GO:0016310 Not Cancer Driver No 62 0.15 39 3 0.077 3
BMP10 BMP10 O95393 Bone morphogenetic protein 10 chr2 GO:0016310 Not Cancer Driver No 88 0.208 87 13 0.149 0
BMP2 BMP2 P12643 Bone morphogenetic protein 2 chr20 GO:0016310 Not Cancer Driver No 73 0.184 139 26 0.187 0
BMP4 BMP4 P12644 Bone morphogenetic protein 4 chr14 GO:0016310 Not Cancer Driver No 86 0.211 142 26 0.183 5
BMX_ENST00000342014 BMX P51813 Cytoplasmic tyrosine-protein kinase BMX chrX GO:0016310 Not Cancer Driver No 106 0.157 172 27 0.157 0
CAMK2A_ENST00000348628 CAMK2A Q9UQM7 Calcium/calmodulin-dependent protein kinase type II subunit alpha chr5 GO:0016310 Not Cancer Driver No 83 0.174 62 10 0.161 7
CCNA2_ENST00000618014 CCNA2 P20248 Cyclin-A2 chr4 GO:0016310 Not Cancer Driver No 45 0.104 186 19 0.102 0
CCNT1 CCNT1 O60563 Cyclin-T1 chr12 GO:0016310 Not Cancer Driver No 85 0.117 495 61 0.123 0
CDK1 CDK1 P06493 Cyclin-dependent kinase 1 chr10 GO:0016310 Not Cancer Driver No 40 0.135 1 0 0.0 0
CDK2 CDK2 P24941 Cyclin-dependent kinase 2 chr12 GO:0016310 Not Cancer Driver No 24 0.081 0 0 0.0 0
CDK5 CDK5 Q00535 Cyclin-dependent kinase 5 chr7 GO:0016310 Not Cancer Driver No 48 0.164 5 1 0.2 0
CDK5R1 CDK5R1 Q15078 Cyclin-dependent kinase 5 activator 1 chr17 GO:0016310 Not Cancer Driver No 35 0.114 103 16 0.155 0
CDK9 CDK9 P50750 Cyclin-dependent kinase 9 chr9 GO:0016310 Not Cancer Driver No 50 0.134 34 2 0.059 0
CERK CERK Q8TCT0 Ceramide kinase chr22 GO:0016310 Not Cancer Driver No 56 0.104 48 5 0.104 0
CERKL CERKL Q49MI3 Ceramide kinase-like protein chr2 GO:0016310 Not Cancer Driver No 126 0.226 89 27 0.303 1
CHEK1_ENST00000428830 CHEK1 O14757 Serine/threonine-protein kinase Chk1 chr11 GO:0016310 Not Cancer Driver No 58 0.122 86 16 0.186 0
CHEK2_ENST00000405598 CHEK2 O96017 Serine/threonine-protein kinase Chk2 chr22 GO:0016310 Census, Compendium Yes 335 0.617 157 130 0.828 13
CHKA CHKA P35790 Choline kinase alpha chr11 GO:0016310 Not Cancer Driver No 45 0.098 119 4 0.034 0
CHKB CHKB Q9Y259 Choline/ethanolamine kinase chr22 GO:0016310 Not Cancer Driver No 42 0.106 37 3 0.081 2
CHUK CHUK O15111 Inhibitor of nuclear factor kappa-B kinase subunit alpha chr10 GO:0016310 Not Cancer Driver No 74 0.099 116 9 0.078 0
CKB CKB P12277 Creatine kinase B-type chr14 GO:0016310 Not Cancer Driver No 31 0.081 102 4 0.039 0
CKM CKM P06732 Creatine kinase M-type chr19 GO:0016310 Not Cancer Driver No 58 0.152 118 19 0.161 0
CKMT1B_ENST00000441322 CKMT1B P12532 Creatine kinase U-type, mitochondrial chr15 GO:0016310 Not Cancer Driver No 25 0.06 77 1 0.013 0
CKMT2_ENST00000437669 CKMT2 P17540 Creatine kinase S-type, mitochondrial chr5 GO:0016310 Not Cancer Driver No 70 0.167 68 12 0.176 0
CLP1 CLP1 Q92989 Polyribonucleotide 5'-hydroxyl-kinase Clp1 chr11 GO:0016310 Census Yes 59 0.139 58 12 0.207 1
COASY_ENST00000421097 COASY Q13057 Bifunctional coenzyme A synthase chr17 GO:0016310 Not Cancer Driver No 57 0.101 50 4 0.08 1
COL4A3BP_ENST00000261415 CERT1 Q9Y5P4 Ceramide transfer protein chr5 GO:0016310 Not Cancer Driver No 73 0.117 215 23 0.107 2
COQ8A COQ8A Q8NI60 Atypical kinase COQ8A, mitochondrial chr1 GO:0016310 Not Cancer Driver No 95 0.147 166 29 0.175 12
CRY1 CRY1 Q16526 Cryptochrome-1 chr12 GO:0016310 Not Cancer Driver No 76 0.13 91 5 0.055 0
DAB2IP_ENST00000408936 DAB2IP Q5VWQ8 Disabled homolog 2-interacting protein chr9 GO:0016310 Not Cancer Driver No 131 0.11 681 68 0.1 0
DCAF1 DCAF1 Q9Y4B6 DDB1- and CUL4-associated factor 1 chr3 GO:0016310 Not Cancer Driver No 128 0.085 495 44 0.089 0
DCAKD DCAKD Q8WVC6 Dephospho-CoA kinase domain-containing protein chr17 GO:0016310 Not Cancer Driver No 31 0.134 2 0 0.0 0
DCK DCK P27707 Deoxycytidine kinase chr4 GO:0016310 Not Cancer Driver No 29 0.112 22 4 0.182 0
DDR1_ENST00000324771 DDR1 Q08345 Epithelial discoidin domain-containing receptor 1 chr6 GO:0016310 Not Cancer Driver No 123 0.135 253 49 0.194 0
DGKA DGKA P23743 Diacylglycerol kinase alpha chr12 GO:0016310 Not Cancer Driver No 87 0.118 76 14 0.184 0
DGKB DGKB Q9Y6T7 Diacylglycerol kinase beta chr7 GO:0016310 Not Cancer Driver No 227 0.282 163 66 0.405 0
DGKD DGKD Q16760 Diacylglycerol kinase delta chr2 GO:0016310 Not Cancer Driver No 160 0.132 441 60 0.136 0
DGKE DGKE P52429 Diacylglycerol kinase epsilon chr17 GO:0016310 Not Cancer Driver No 84 0.148 34 3 0.088 2
DGKG DGKG P49619 Diacylglycerol kinase gamma chr3 GO:0016310 Not Cancer Driver No 160 0.202 182 43 0.236 0
DGKH DGKH Q86XP1 Diacylglycerol kinase eta chr13 GO:0016310 Not Cancer Driver No 138 0.113 326 43 0.132 0
DGKI DGKI O75912 Diacylglycerol kinase iota chr7 GO:0016310 Not Cancer Driver No 243 0.228 355 62 0.175 0
DGKK DGKK Q5KSL6 Diacylglycerol kinase kappa chrX GO:0016310 Not Cancer Driver No 262 0.206 382 90 0.236 0
DGKQ DGKQ P52824 Diacylglycerol kinase theta chr4 GO:0016310 Not Cancer Driver No 56 0.059 264 11 0.042 0
DGKZ_ENST00000456247 DGKZ Q13574 Diacylglycerol kinase zeta chr11 GO:0016310 Not Cancer Driver No 87 0.094 410 42 0.102 0
DOLK DOLK Q9UPQ8 Dolichol kinase chr9 GO:0016310 Not Cancer Driver No 49 0.091 12 1 0.083 2
DRD1 DRD1 P21728 D(1A) dopamine receptor chr5 GO:0016310 Not Cancer Driver No 73 0.164 30 4 0.133 0
DYRK1A_ENST00000644942 DYRK1A Q13627 Dual specificity tyrosine-phosphorylation-regulated kinase 1A chr21 GO:0016310 Not Cancer Driver No 135 0.177 447 73 0.163 0
EGFR EGFR P00533 Epidermal growth factor receptor chr7 GO:0016310 Census, Compendium Yes 444 0.367 223 35 0.157 1
EIF2AK1 EIF2AK1 Q9BQI3 Eukaryotic translation initiation factor 2-alpha kinase 1 chr7 GO:0016310 Not Cancer Driver No 87 0.138 238 29 0.122 0
EIF2AK2_ENST00000395127 EIF2AK2 P19525 Interferon-induced, double-stranded RNA-activated protein kinase chr2 GO:0016310 Not Cancer Driver No 59 0.107 188 22 0.117 0
EIF2AK3 EIF2AK3 Q9NZJ5 Eukaryotic translation initiation factor 2-alpha kinase 3 chr2 GO:0016310 Not Cancer Driver No 149 0.134 410 51 0.124 1
EIF2AK4 EIF2AK4 Q9P2K8 eIF-2-alpha kinase GCN2 chr15 GO:0016310 Not Cancer Driver No 156 0.095 494 44 0.089 2
ENO1 ENO1 P06733 Alpha-enolase chr1 GO:0016310 Not Cancer Driver No 51 0.118 21 2 0.095 0
ENO2 ENO2 P09104 Gamma-enolase chr12 GO:0016310 Not Cancer Driver No 48 0.111 12 2 0.167 0
EPHA7 EPHA7 Q15375 Ephrin type-A receptor 7 chr6 GO:0016310 Census, Compendium Yes 280 0.281 71 15 0.211 0
EPHB2 EPHB2 P29323 Ephrin type-B receptor 2 chr1 GO:0016310 Not Cancer Driver No 186 0.176 119 17 0.143 7
ERC1 ERC1 Q8IUD2 ELKS/Rab6-interacting/CAST family member 1 chr12 GO:0016310 Census Yes 127 0.114 1013 119 0.117 0
ERN1 ERN1 O75460 Serine/threonine-protein kinase/endoribonuclease IRE1 chr17 GO:0016310 Not Cancer Driver No 125 0.128 250 28 0.112 0
ETNK1 ETNK1 Q9HBU6 Ethanolamine kinase 1 chr12 GO:0016310 Census Yes 49 0.108 81 5 0.062 0
ETNK2_ENST00000367202 ETNK2 Q9NVF9 Ethanolamine kinase 2 chr1 GO:0016310 Not Cancer Driver No 46 0.119 38 34 0.895 0
FGGY_ENST00000303721 FGGY Q96C11 FGGY carbohydrate kinase domain-containing protein chr1 GO:0016310 Not Cancer Driver No 82 0.149 14 2 0.143 0
FN3K FN3K Q9H479 Fructosamine-3-kinase chr17 GO:0016310 Not Cancer Driver No 36 0.117 40 3 0.075 0
FN3KRP FN3KRP Q9HA64 Ketosamine-3-kinase chr17 GO:0016310 Not Cancer Driver No 36 0.117 75 5 0.067 0
FOXK1 FOXK1 P85037 Forkhead box protein K1 chr7 GO:0016310 Not Cancer Driver No 97 0.132 511 65 0.127 0
FOXK2 FOXK2 Q01167 Forkhead box protein K2 chr17 GO:0016310 Not Cancer Driver No 79 0.12 548 64 0.117 0
FUK FCSK Q8N0W3 L-fucose kinase chr16 GO:0016310 Not Cancer Driver No 102 0.094 26 1 0.038 0
GALK1 GALK1 P51570 Galactokinase chr17 GO:0016310 Not Cancer Driver No 31 0.079 43 5 0.116 11
GALK2 GALK2 Q01415 N-acetylgalactosamine kinase chr15 GO:0016310 Not Cancer Driver No 48 0.105 17 1 0.059 0
GCK_ENST00000403799 GCK P35557 Hexokinase-4 chr7 GO:0016310 Not Cancer Driver No 88 0.189 73 14 0.192 107
GDF6 GDF6 Q6KF10 Growth/differentiation factor 6 chr8 GO:0016310 Not Cancer Driver No 91 0.2 225 46 0.204 14
GDF7 GDF7 Q7Z4P5 Growth/differentiation factor 7 chr2 GO:0016310 Not Cancer Driver No 33 0.073 213 8 0.038 0
GHR_ENST00000612382 GHR P10912 Growth hormone receptor chr5 GO:0016310 Not Cancer Driver No 173 0.271 229 66 0.288 19
GK GK P32189 Glycerol kinase chrX GO:0016310 Not Cancer Driver No 85 0.152 15 3 0.2 3
GK2 GK2 Q14410 Glycerol kinase 2 chr4 GO:0016310 Not Cancer Driver No 175 0.316 14 3 0.214 0
GK3P GK3P Q14409 Glycerol kinase 3 chr4 GO:0016310 Not Cancer Driver No 9 0.016 17 1 0.059 0
GK5 GK5 Q6ZS86 Putative glycerol kinase 5 chr3 GO:0016310 Not Cancer Driver No 42 0.079 9 1 0.111 0
GNE_ENST00000539815 GNE Q9Y223 Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase chr9 GO:0016310 Not Cancer Driver No 83 0.115 15 2 0.133 36
GNPTAB GNPTAB Q3T906 N-acetylglucosamine-1-phosphotransferase subunits alpha/beta chr12 GO:0016310 Not Cancer Driver No 144 0.115 259 23 0.089 25
GNPTG GNPTG Q9UJJ9 N-acetylglucosamine-1-phosphotransferase subunit gamma chr16 GO:0016310 Not Cancer Driver No 22 0.072 131 9 0.069 3
GUK1_ENST00000366718 GUK1 Q16774 Guanylate kinase chr1 GO:0016310 Not Cancer Driver No 28 0.142 71 9 0.127 0
HASPIN HASPIN Q8TF76 Serine/threonine-protein kinase haspin chr17 GO:0016310 Not Cancer Driver No 87 0.109 373 36 0.097 0
HIPK4 HIPK4 Q8NE63 Homeodomain-interacting protein kinase 4 chr19 GO:0016310 Not Cancer Driver No 87 0.141 258 23 0.089 0
HK1_ENST00000359426 HK1 P19367 Hexokinase-1 chr10 GO:0016310 Not Cancer Driver No 127 0.138 75 16 0.213 6
HK2 HK2 P52789 Hexokinase-2 chr2 GO:0016310 Not Cancer Driver No 138 0.15 77 7 0.091 0
HK3 HK3 P52790 Hexokinase-3 chr5 GO:0016310 Not Cancer Driver No 164 0.178 71 17 0.239 0
HKDC1 HKDC1 Q2TB90 Hexokinase HKDC1 chr10 GO:0016310 Not Cancer Driver No 146 0.159 33 3 0.091 0
HMGA2_ENST00000403681 HMGA2 P52926 High mobility group protein HMGI-C chr12 GO:0016310 Census Yes 12 0.11 109 12 0.11 0
HTR2B HTR2B P41595 5-hydroxytryptamine receptor 2B chr2 GO:0016310 Not Cancer Driver No 41 0.085 23 2 0.087 0
HYKK_ENST00000388988 HYKK A2RU49 Hydroxylysine kinase chr15 GO:0016310 Not Cancer Driver No 38 0.102 30 3 0.1 0
IDNK IDNK Q5T6J7 Probable gluconokinase chr9 GO:0016310 Not Cancer Driver No 19 0.102 27 5 0.185 0
IGF1R IGF1R P08069 Insulin-like growth factor 1 receptor chr15 GO:0016310 Not Cancer Driver No 183 0.134 265 37 0.14 6
IKBKB IKBKB O14920 Inhibitor of nuclear factor kappa-B kinase subunit beta chr8 GO:0016310 Census, Compendium Yes 106 0.14 211 31 0.147 1
IKBKE IKBKE Q14164 Inhibitor of nuclear factor kappa-B kinase subunit epsilon chr1 GO:0016310 Not Cancer Driver No 108 0.151 76 13 0.171 0
IL24_ENST00000294984 IL24 Q13007 Interleukin-24 chr1 GO:0016310 Not Cancer Driver No 35 0.17 0 0 0.0 0
IL4 IL4 P05112 Interleukin-4 chr5 GO:0016310 Not Cancer Driver No 18 0.118 0 0 0.0 0
INCENP INCENP Q9NQS7 Inner centromere protein chr11 GO:0016310 Not Cancer Driver No 107 0.117 856 103 0.12 0
INSR INSR P06213 Insulin receptor chr19 GO:0016310 Not Cancer Driver No 190 0.137 280 57 0.204 64
IP6K1 IP6K1 Q92551 Inositol hexakisphosphate kinase 1 chr3 GO:0016310 Not Cancer Driver No 50 0.113 216 29 0.134 0
IP6K2 IP6K2 Q9UHH9 Inositol hexakisphosphate kinase 2 chr3 GO:0016310 Not Cancer Driver No 45 0.106 96 10 0.104 0
IPMK IPMK Q8NFU5 Inositol polyphosphate multikinase chr10 GO:0016310 Not Cancer Driver No 50 0.12 108 9 0.083 0
IPPK IPPK Q9H8X2 Inositol-pentakisphosphate 2-kinase chr9 GO:0016310 Not Cancer Driver No 55 0.112 43 3 0.07 0
ITK ITK Q08881 Tyrosine-protein kinase ITK/TSK chr5 GO:0016310 Census Yes 139 0.224 43 10 0.233 1
ITPK1 ITPK1 Q13572 Inositol-tetrakisphosphate 1-kinase chr14 GO:0016310 Not Cancer Driver No 74 0.179 24 1 0.042 0
ITPKB_ENST00000272117 ITPKB P27987 Inositol-trisphosphate 3-kinase B chr1 GO:0016310 Not Cancer Driver No 148 0.156 719 119 0.166 0
ITPKC ITPKC Q96DU7 Inositol-trisphosphate 3-kinase C chr19 GO:0016310 Not Cancer Driver No 78 0.114 452 38 0.084 0
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 GO:0016310 Census, Compendium Yes 136 0.12 59 5 0.085 5
KDR KDR P35968 Vascular endothelial growth factor receptor 2 chr4 GO:0016310 Census, Compendium Yes 357 0.263 275 55 0.2 2
KHK_ENST00000260598 KHK P50053 Ketohexokinase chr2 GO:0016310 Not Cancer Driver No 38 0.128 42 4 0.095 2
LIMD1 LIMD1 Q9UGP4 LIM domain-containing protein 1 chr3 GO:0016310 Not Cancer Driver No 58 0.086 428 36 0.084 0
LIMK2_ENST00000331728 LIMK2 P53671 LIM domain kinase 2 chr22 GO:0016310 Not Cancer Driver No 93 0.146 146 29 0.199 0
LRGUK LRGUK Q96M69 Leucine-rich repeat and guanylate kinase domain-containing protein chr7 GO:0016310 Not Cancer Driver No 145 0.176 204 37 0.181 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 GO:0016310 Not Cancer Driver No 519 0.205 90 17 0.189 23
MAP2K2 MAP2K2 P36507 Dual specificity mitogen-activated protein kinase kinase 2 chr19 GO:0016310 Census Yes 58 0.145 105 14 0.133 4
MAP2K6 MAP2K6 P52564 Dual specificity mitogen-activated protein kinase kinase 6 chr17 GO:0016310 Not Cancer Driver No 48 0.144 55 11 0.2 0
MAP3K12_ENST00000267079 MAP3K12 Q12852 Mitogen-activated protein kinase kinase kinase 12 chr12 GO:0016310 Not Cancer Driver No 120 0.14 481 64 0.133 0
MAP3K7 MAP3K7 O43318 Mitogen-activated protein kinase kinase kinase 7 chr6 GO:0016310 Not Cancer Driver No 104 0.172 333 66 0.198 6
MAPK12 MAPK12 P53778 Mitogen-activated protein kinase 12 chr22 GO:0016310 Not Cancer Driver No 31 0.084 63 5 0.079 0
MAPK3 MAPK3 P27361 Mitogen-activated protein kinase 3 chr16 GO:0016310 Not Cancer Driver No 38 0.1 49 5 0.102 0
MAPK8IP1 MAPK8IP1 Q9UQF2 C-Jun-amino-terminal kinase-interacting protein 1 chr11 GO:0016310 Not Cancer Driver No 79 0.111 444 40 0.09 1
MAPK8_ENST00000374189 MAPK8 P45983 Mitogen-activated protein kinase 8 chr10 GO:0016310 Not Cancer Driver No 64 0.15 94 9 0.096 0
MAPKAP1 MAPKAP1 Q9BPZ7 Target of rapamycin complex 2 subunit MAPKAP1 chr9 GO:0016310 Not Cancer Driver No 70 0.134 173 25 0.145 0
MARK3 MARK3 P27448 MAP/microtubule affinity-regulating kinase 3 chr14 GO:0016310 Not Cancer Driver No 92 0.122 376 49 0.13 1
MLST8_ENST00000397124 MLST8 Q9BVC4 Target of rapamycin complex subunit LST8 chr16 GO:0016310 Not Cancer Driver No 37 0.113 45 3 0.067 0
MST1 MST1 P26927 Hepatocyte growth factor-like protein chr3 GO:0016310 Not Cancer Driver No 110 0.155 168 19 0.113 0
MTOR MTOR P42345 Serine/threonine-protein kinase mTOR chr1 GO:0016310 Census, Compendium Yes 379 0.149 296 37 0.125 18
MVK MVK Q03426 Mevalonate kinase chr12 GO:0016310 Not Cancer Driver No 50 0.126 25 0 0.0 38
N4BP2 N4BP2 Q86UW6 NEDD4-binding protein 2 chr4 GO:0016310 Census Yes 185 0.105 965 104 0.108 0
NADK2 NADK2 Q4G0N4 NAD kinase 2, mitochondrial chr5 GO:0016310 Not Cancer Driver No 42 0.095 89 3 0.034 0
NADK_ENST00000341991 NADK O95544 NAD kinase chr1 GO:0016310 Not Cancer Driver No 59 0.132 91 18 0.198 0
NAGK_ENST00000244204 NAGK Q9UJ70 N-acetyl-D-glucosamine kinase chr2 GO:0016310 Not Cancer Driver No 46 0.134 5 1 0.2 0
NEK11 NEK11 Q8NG66 Serine/threonine-protein kinase Nek11 chr3 GO:0016310 Not Cancer Driver No 91 0.141 264 45 0.17 0
NLK NLK Q9UBE8 Serine/threonine-protein kinase NLK chr17 GO:0016310 Not Cancer Driver No 54 0.102 152 20 0.132 0
NME2 NME2 P22392 Nucleoside diphosphate kinase B chr17 GO:0016310 Not Cancer Driver No 13 0.086 11 1 0.091 0
NMRK1_ENST00000361092 NMRK1 Q9NWW6 Nicotinamide riboside kinase 1 chr9 GO:0016310 Not Cancer Driver No 23 0.116 6 0 0.0 0
NMRK2_ENST00000168977 NMRK2 Q9NPI5 Nicotinamide riboside kinase 2 chr19 GO:0016310 Not Cancer Driver No 25 0.109 53 9 0.17 0
NOL9 NOL9 Q5SY16 Polynucleotide 5'-hydroxyl-kinase NOL9 chr1 GO:0016310 Not Cancer Driver No 73 0.104 102 8 0.078 0
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 GO:0016310 Census, Compendium Yes 168 0.211 57 8 0.14 25
PAK1_ENST00000356341 PAK1 Q13153 Serine/threonine-protein kinase PAK 1 chr11 GO:0016310 Not Cancer Driver No 57 0.105 299 30 0.1 2
PAK2 PAK2 Q13177 Serine/threonine-protein kinase PAK 2 chr3 GO:0016310 Compendium Yes 89 0.17 242 49 0.202 0
PANK1 PANK1 Q8TE04 Pantothenate kinase 1 chr10 GO:0016310 Not Cancer Driver No 62 0.104 248 17 0.069 0
PANK2 PANK2 Q9BZ23 Pantothenate kinase 2, mitochondrial chr20 GO:0016310 Not Cancer Driver No 46 0.081 206 14 0.068 30
PANK3 PANK3 Q9H999 Pantothenate kinase 3 chr5 GO:0016310 Not Cancer Driver No 41 0.111 0 0 0.0 0
PAPSS1 PAPSS1 O43252 Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 chr4 GO:0016310 Not Cancer Driver No 94 0.151 82 14 0.171 0
PAPSS2_ENST00000361175 PAPSS2 O95340 Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 chr10 GO:0016310 Not Cancer Driver No 81 0.132 100 7 0.07 4
PDXK PDXK O00764 Pyridoxal kinase chr21 GO:0016310 Not Cancer Driver No 27 0.087 47 6 0.128 2
PFKFB1 PFKFB1 P16118 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 chrX GO:0016310 Not Cancer Driver No 81 0.172 48 11 0.229 0
PFKFB2 PFKFB2 O60825 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 chr1 GO:0016310 Not Cancer Driver No 68 0.135 97 18 0.186 0
PFKFB3_ENST00000379775 PFKFB3 Q16875 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 chr10 GO:0016310 Not Cancer Driver No 65 0.125 97 19 0.196 0
PFKFB4 PFKFB4 Q16877 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 chr3 GO:0016310 Not Cancer Driver No 71 0.151 44 3 0.068 0
PFKL PFKL P17858 ATP-dependent 6-phosphofructokinase, liver type chr21 GO:0016310 Not Cancer Driver No 91 0.117 29 4 0.138 0
PFKM_ENST00000550924 PFKM P08237 ATP-dependent 6-phosphofructokinase, muscle type chr12 GO:0016310 Not Cancer Driver No 80 0.103 70 8 0.114 9
PFKP PFKP Q01813 ATP-dependent 6-phosphofructokinase, platelet type chr10 GO:0016310 Not Cancer Driver No 133 0.17 43 10 0.233 0
PGK1 PGK1 P00558 Phosphoglycerate kinase 1 chrX GO:0016310 Not Cancer Driver No 61 0.146 40 5 0.125 9
PGK2 PGK2 P07205 Phosphoglycerate kinase 2 chr6 GO:0016310 Not Cancer Driver No 145 0.348 37 13 0.351 0
PGM2L1 PGM2L1 Q6PCE3 Glucose 1,6-bisphosphate synthase chr11 GO:0016310 Not Cancer Driver No 62 0.1 66 6 0.091 0
PI4K2A PI4K2A Q9BTU6 Phosphatidylinositol 4-kinase type 2-alpha chr10 GO:0016310 Not Cancer Driver No 43 0.09 129 6 0.047 0
PI4K2B PI4K2B Q8TCG2 Phosphatidylinositol 4-kinase type 2-beta chr4 GO:0016310 Not Cancer Driver No 51 0.106 99 4 0.04 0
PI4KA PI4KA P42356 Phosphatidylinositol 4-kinase alpha chr22 GO:0016310 Not Cancer Driver No 267 0.127 142 11 0.077 1
PI4KB_ENST00000368873 PI4KB Q9UBF8 Phosphatidylinositol 4-kinase beta chr1 GO:0016310 Not Cancer Driver No 93 0.114 311 34 0.109 0
PIBF1 PIBF1 Q8WXW3 Progesterone-induced-blocking factor 1 chr13 GO:0016310 Not Cancer Driver No 83 0.11 419 45 0.107 2
PIK3C2A PIK3C2A O00443 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha chr11 GO:0016310 Not Cancer Driver No 187 0.111 350 43 0.123 0
PIK3C2B PIK3C2B O00750 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta chr1 GO:0016310 Not Cancer Driver No 241 0.147 425 71 0.167 0
PIK3C2G_ENST00000433979 PIK3C2G O75747 Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma chr12 GO:0016310 Not Cancer Driver No 283 0.196 211 37 0.175 0
PIK3CA PIK3CA P42336 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform chr3 GO:0016310 Census, Compendium Yes 1669 1.563 38 11 0.289 30
PIK3CB_ENST00000477593 PIK3CB P42338 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform chr3 GO:0016310 Census, Compendium Yes 150 0.14 42 4 0.095 0
PIK3CD PIK3CD O00329 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform chr1 GO:0016310 Not Cancer Driver No 140 0.134 60 13 0.217 1
PIK3CG PIK3CG P48736 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform chr7 GO:0016310 Not Cancer Driver No 318 0.289 121 39 0.322 0
PIKFYVE PIKFYVE Q9Y2I7 1-phosphatidylinositol 3-phosphate 5-kinase chr2 GO:0016310 Not Cancer Driver No 278 0.133 848 101 0.119 1
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 GO:0016310 Not Cancer Driver No 57 0.098 99 13 0.131 23
PIP4K2A PIP4K2A P48426 Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha chr10 GO:0016310 Not Cancer Driver No 56 0.138 123 15 0.122 0
PIP4K2C_ENST00000540759 PIP4K2C Q8TBX8 Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma chr12 GO:0016310 Not Cancer Driver No 62 0.147 111 23 0.207 0
PIP5K1A PIP5K1A Q99755 Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha chr1 GO:0016310 Not Cancer Driver No 74 0.132 216 29 0.134 0
PIP5K1B PIP5K1B O14986 Phosphatidylinositol 4-phosphate 5-kinase type-1 beta chr9 GO:0016310 Not Cancer Driver No 94 0.174 162 36 0.222 0
PIP5K1C_ENST00000335312 PIP5K1C O60331 Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma chr19 GO:0016310 Not Cancer Driver No 98 0.147 360 60 0.167 1
PIP5KL1 PIP5KL1 Q5T9C9 Phosphatidylinositol 4-phosphate 5-kinase-like protein 1 chr9 GO:0016310 Not Cancer Driver No 28 0.071 74 6 0.081 0
PKN1_ENST00000242783 PKN1 Q16512 Serine/threonine-protein kinase N1 chr19 GO:0016310 Not Cancer Driver No 120 0.127 459 54 0.118 0
PML PML P29590 Protein PML chr15 GO:0016310 Census, Compendium Yes 112 0.127 312 34 0.109 0
PMVK PMVK Q15126 Phosphomevalonate kinase chr1 GO:0016310 Not Cancer Driver No 38 0.198 3 0 0.0 0
POMK POMK Q9H5K3 Protein O-mannose kinase chr8 GO:0016310 Not Cancer Driver No 53 0.151 30 9 0.3 3
PPIP5K1 PPIP5K1 Q6PFW1 Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 chr15 GO:0016310 Not Cancer Driver No 58 0.04 544 25 0.046 0
PPIP5K2_ENST00000358359 PPIP5K2 O43314 Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 chr5 GO:0016310 Not Cancer Driver No 146 0.117 419 54 0.129 1
PRDX4 PRDX4 Q13162 Peroxiredoxin-4 chrX GO:0016310 Not Cancer Driver No 36 0.133 29 2 0.069 0
PRKAA1_ENST00000397128 PRKAA1 Q13131 5'-AMP-activated protein kinase catalytic subunit alpha-1 chr5 GO:0016310 Not Cancer Driver No 72 0.129 124 17 0.137 0
PRKAA2 PRKAA2 P54646 5'-AMP-activated protein kinase catalytic subunit alpha-2 chr1 GO:0016310 Not Cancer Driver No 128 0.232 98 26 0.265 0
PRKCA PRKCA P17252 Protein kinase C alpha type chr17 GO:0016310 Not Cancer Driver No 94 0.14 154 22 0.143 0
PRKCB_ENST00000321728 PRKCB P05771 Protein kinase C beta type chr16 GO:0016310 Census, Compendium Yes 205 0.306 148 40 0.27 0
PRKCD_ENST00000330452 PRKCD Q05655 Protein kinase C delta type chr3 GO:0016310 Compendium Yes 79 0.117 43 9 0.209 0
PRKCG PRKCG P05129 Protein kinase C gamma type chr19 GO:0016310 Not Cancer Driver No 172 0.247 151 43 0.285 5
PRKG2 PRKG2 Q13237 cGMP-dependent protein kinase 2 chr4 GO:0016310 Not Cancer Driver No 138 0.181 217 48 0.221 0
PRLR PRLR P16471 Prolactin receptor chr5 GO:0016310 Not Cancer Driver No 154 0.248 282 70 0.248 2
PRPS1 PRPS1 P60891 Ribose-phosphate pyrophosphokinase 1 chrX GO:0016310 Not Cancer Driver No 50 0.157 0 0 0.0 14
PRPS1L1_ENST00000638645 PRPS1L1 P21108 Ribose-phosphate pyrophosphokinase 3 chr7 GO:0016310 Not Cancer Driver No 83 0.261 0 0 0.0 0
PRPS2_ENST00000380668 PRPS2 P11908 Ribose-phosphate pyrophosphokinase 2 chrX GO:0016310 Not Cancer Driver No 56 0.176 4 1 0.25 0
PRR5_ENST00000336985 PRR5 P85299 Proline-rich protein 5 chr22 GO:0016310 Not Cancer Driver No 50 0.129 173 22 0.127 0
PSTK PSTK Q8IV42 L-seryl-tRNA(Sec) kinase chr10 GO:0016310 Not Cancer Driver No 48 0.138 79 15 0.19 0
PTK2B_ENST00000346049 PTK2B Q14289 Protein-tyrosine kinase 2-beta chr8 GO:0016310 Not Cancer Driver No 161 0.16 261 37 0.142 0
RBKS RBKS Q9H477 Ribokinase chr2 GO:0016310 Not Cancer Driver No 27 0.084 28 5 0.179 0
RFK RFK Q969G6 Riboflavin kinase chr9 GO:0016310 Not Cancer Driver No 15 0.097 1 0 0.0 0
RICTOR_ENST00000357387 RICTOR Q6R327 Rapamycin-insensitive companion of mTOR chr5 GO:0016310 Not Cancer Driver No 212 0.124 366 50 0.137 0
RIPK1_ENST00000380409 RIPK1 Q13546 Receptor-interacting serine/threonine-protein kinase 1 chr6 GO:0016310 Compendium Yes 82 0.122 277 39 0.141 4
RPS6KA4 RPS6KA4 O75676 Ribosomal protein S6 kinase alpha-4 chr11 GO:0016310 Not Cancer Driver No 72 0.093 220 11 0.05 0
RPS6KA5 RPS6KA5 O75582 Ribosomal protein S6 kinase alpha-5 chr14 GO:0016310 Not Cancer Driver No 97 0.121 187 18 0.096 0
RPTOR RPTOR Q8N122 Regulatory-associated protein of mTOR chr17 GO:0016310 Not Cancer Driver No 176 0.132 241 21 0.087 0
SEPHS1 SEPHS1 P49903 Selenide, water dikinase 1 chr10 GO:0016310 Not Cancer Driver No 58 0.148 29 10 0.345 0
SEPHS2 SEPHS2 Q99611 Selenide, water dikinase 2 chr16 GO:0016310 Not Cancer Driver No 48 0.107 104 2 0.019 0
SGMS1 SGMS1 Q86VZ5 Phosphatidylcholine:ceramide cholinephosphotransferase 1 chr10 GO:0016310 Not Cancer Driver No 85 0.206 37 8 0.216 0
SGMS2 SGMS2 Q8NHU3 Phosphatidylcholine:ceramide cholinephosphotransferase 2 chr4 GO:0016310 Not Cancer Driver No 37 0.101 49 7 0.143 0
SHPK SHPK Q9UHJ6 Sedoheptulokinase chr17 GO:0016310 Not Cancer Driver No 44 0.092 31 1 0.032 0
SMAD2_ENST00000402690 SMAD2 Q15796 Mothers against decapentaplegic homolog 2 chr18 GO:0016310 Census, Compendium Yes 79 0.169 137 12 0.088 0
SMAD7 SMAD7 O15105 Mothers against decapentaplegic homolog 7 chr18 GO:0016310 Not Cancer Driver No 40 0.094 139 0 0.0 0
SMARCA5 SMARCA5 O60264 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 chr4 GO:0016310 Not Cancer Driver No 116 0.11 363 48 0.132 0
SPHK1_ENST00000545180 SPHK1 Q9NYA1 Sphingosine kinase 1 chr17 GO:0016310 Not Cancer Driver No 47 0.122 25 2 0.08 0
SPHK2 SPHK2 Q9NRA0 Sphingosine kinase 2 chr19 GO:0016310 Not Cancer Driver No 82 0.125 293 39 0.133 0
SPTBN1 SPTBN1 Q01082 Spectrin beta chain, non-erythrocytic 1 chr2 GO:0016310 Not Cancer Driver No 311 0.132 869 123 0.142 0
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:0016310 Census Yes 53 0.099 130 11 0.085 1
SRMS SRMS Q9H3Y6 Tyrosine-protein kinase Srms chr20 GO:0016310 Not Cancer Driver No 77 0.158 48 11 0.229 0
STAT3 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 GO:0016310 Census, Compendium Yes 110 0.143 152 15 0.099 19
TAOK1 TAOK1 Q7L7X3 Serine/threonine-protein kinase TAO1 chr17 GO:0016310 Not Cancer Driver No 116 0.116 601 59 0.098 0
TEC TEC P42680 Tyrosine-protein kinase Tec chr4 GO:0016310 Census, Compendium Yes 91 0.144 57 15 0.263 0
TGFB1 TGFB1 P01137 Transforming growth factor beta-1 proprotein chr19 GO:0016310 Not Cancer Driver No 41 0.105 41 4 0.098 10
TGFB2_ENST00000366930 TGFB2 P61812 Transforming growth factor beta-2 proprotein chr1 GO:0016310 Not Cancer Driver No 63 0.152 47 8 0.17 3
TGFBR1_ENST00000374994 TGFBR1 P36897 TGF-beta receptor type-1 chr9 GO:0016310 Not Cancer Driver No 86 0.171 23 3 0.13 15
TGFBR2_ENST00000295754 TGFBR2 P37173 TGF-beta receptor type-2 chr3 GO:0016310 Census, Compendium Yes 106 0.187 60 16 0.267 25
TGFBR3_ENST00000525962 TGFBR3 Q03167 Transforming growth factor beta receptor type 3 chr1 GO:0016310 Not Cancer Driver No 129 0.152 268 41 0.153 0
TK1 TK1 P04183 Thymidine kinase, cytosolic chr17 GO:0016310 Not Cancer Driver No 26 0.111 13 4 0.308 0
TK2 TK2 O00142 Thymidine kinase 2, mitochondrial chr16 GO:0016310 Not Cancer Driver No 23 0.087 44 3 0.068 11
TKFC TKFC Q3LXA3 Triokinase/FMN cyclase chr11 GO:0016310 Not Cancer Driver No 66 0.115 91 14 0.154 2
TLR2 TLR2 O60603 Toll-like receptor 2 chr4 GO:0016310 Not Cancer Driver No 108 0.138 0 0 0.0 0
TLR3 TLR3 O15455 Toll-like receptor 3 chr4 GO:0016310 Not Cancer Driver No 123 0.136 0 0 0.0 1
TLR4_ENST00000355622 TLR4 O00206 Toll-like receptor 4 chr9 GO:0016310 Not Cancer Driver No 292 0.348 0 0 0.0 0
TLR7 TLR7 Q9NYK1 Toll-like receptor 7 chrX GO:0016310 Not Cancer Driver No 182 0.173 14 1 0.071 1
TLR9 TLR9 Q9NR96 Toll-like receptor 9 chr3 GO:0016310 Not Cancer Driver No 141 0.137 35 3 0.086 0
TNK2_ENST00000333602 TNK2 Q07912 Activated CDC42 kinase 1 chr3 GO:0016310 Not Cancer Driver No 137 0.132 593 81 0.137 0
TOLLIP TOLLIP Q9H0E2 Toll-interacting protein chr11 GO:0016310 Not Cancer Driver No 38 0.139 81 12 0.148 0
TOP1 TOP1 P11387 DNA topoisomerase 1 chr20 GO:0016310 Census, Compendium Yes 93 0.122 391 53 0.136 0
TPK1 TPK1 Q9H3S4 Thiamin pyrophosphokinase 1 chr7 GO:0016310 Not Cancer Driver No 56 0.23 0 0 0.0 3
TSSK4_ENST00000287913 TSSK4 Q6SA08 Testis-specific serine/threonine-protein kinase 4 chr14 GO:0016310 Not Cancer Driver No 29 0.088 8 1 0.125 0
TXK TXK P42681 Tyrosine-protein kinase TXK chr4 GO:0016310 Not Cancer Driver No 87 0.165 61 9 0.148 0
UCK1_ENST00000372215 UCK1 Q9HA47 Uridine-cytidine kinase 1 chr9 GO:0016310 Not Cancer Driver No 35 0.126 70 3 0.043 0
UCK2 UCK2 Q9BZX2 Uridine-cytidine kinase 2 chr1 GO:0016310 Not Cancer Driver No 43 0.165 61 10 0.164 0
UCKL1 UCKL1 Q9NWZ5 Uridine-cytidine kinase-like 1 chr20 GO:0016310 Not Cancer Driver No 54 0.099 134 15 0.112 0
USP15 USP15 Q9Y4E8 Ubiquitin carboxyl-terminal hydrolase 15 chr12 GO:0016310 Not Cancer Driver No 136 0.139 259 39 0.151 0
VRK1 VRK1 Q99986 Serine/threonine-protein kinase VRK1 chr14 GO:0016310 Not Cancer Driver No 52 0.131 80 9 0.113 0
VRK2 VRK2 Q86Y07 Serine/threonine-protein kinase VRK2 chr2 GO:0016310 Not Cancer Driver No 63 0.124 126 15 0.119 0
VRK3_ENST00000594948 VRK3 Q8IV63 Inactive serine/threonine-protein kinase VRK3 chr19 GO:0016310 Not Cancer Driver No 65 0.137 180 18 0.1 0
XYLB XYLB O75191 Xylulose kinase chr3 GO:0016310 Not Cancer Driver No 90 0.168 22 4 0.182 0
ZMPSTE24 ZMPSTE24 O75844 CAAX prenyl protease 1 homolog chr1 GO:0016310 Not Cancer Driver No 67 0.141 23 0 0.0 3