Total number of protein in "GO:0016298" GO term: 91
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AADAC | AADAC | P22760 | Arylacetamide deacetylase | chr3 | GO:0016298 | Not Cancer Driver | No | 80 | 0.201 | 4 | 0 | 0.0 | 0 |
| ABHD3 | ABHD3 | Q8WU67 | Phospholipase ABHD3 | chr18 | GO:0016298 | Not Cancer Driver | No | 43 | 0.105 | 0 | 0 | 0.0 | 0 |
| BDKRB2 | BDKRB2 | P30411 | B2 bradykinin receptor | chr14 | GO:0016298 | Not Cancer Driver | No | 81 | 0.207 | 0 | 0 | 0.0 | 0 |
| CASR_ENST00000638421 | CASR | P41180 | Extracellular calcium-sensing receptor | chr3 | GO:0016298 | Not Cancer Driver | No | 304 | 0.282 | 189 | 60 | 0.317 | 108 |
| CCR1 | CCR1 | P32246 | C-C chemokine receptor type 1 | chr3 | GO:0016298 | Not Cancer Driver | No | 69 | 0.194 | 14 | 5 | 0.357 | 0 |
| CCR5 | CCR5 | P51681 | C-C chemokine receptor type 5 | chr3 | GO:0016298 | Not Cancer Driver | No | 107 | 0.304 | 0 | 0 | 0.0 | 0 |
| CEL | CEL | P19835 | Bile salt-activated lipase | chr9 | GO:0016298 | Not Cancer Driver | No | 101 | 0.134 | 280 | 40 | 0.143 | 0 |
| CES1_ENST00000361503 | CES1 | P23141 | Liver carboxylesterase 1 | chr16 | GO:0016298 | Not Cancer Driver | No | 138 | 0.243 | 41 | 2 | 0.049 | 0 |
| CHRM1 | CHRM1 | P11229 | Muscarinic acetylcholine receptor M1 | chr11 | GO:0016298 | Not Cancer Driver | No | 63 | 0.137 | 131 | 24 | 0.183 | 0 |
| CHRM3_ENST00000615928 | CHRM3 | P20309 | Muscarinic acetylcholine receptor M3 | chr1 | GO:0016298 | Not Cancer Driver | No | 182 | 0.308 | 136 | 42 | 0.309 | 0 |
| CHRM5 | CHRM5 | P08912 | Muscarinic acetylcholine receptor M5 | chr15 | GO:0016298 | Not Cancer Driver | No | 74 | 0.139 | 155 | 20 | 0.129 | 0 |
| DAGLB | DAGLB | Q8NCG7 | Diacylglycerol lipase-beta | chr7 | GO:0016298 | Not Cancer Driver | No | 69 | 0.103 | 37 | 3 | 0.081 | 0 |
| EDNRA | EDNRA | P25101 | Endothelin-1 receptor | chr4 | GO:0016298 | Not Cancer Driver | No | 62 | 0.145 | 21 | 6 | 0.286 | 2 |
| ENPP7 | ENPP7 | Q6UWV6 | Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 | chr17 | GO:0016298 | Not Cancer Driver | No | 102 | 0.223 | 65 | 19 | 0.292 | 0 |
| F2RL2 | F2RL2 | O00254 | Proteinase-activated receptor 3 | chr5 | GO:0016298 | Not Cancer Driver | No | 54 | 0.144 | 0 | 0 | 0.0 | 0 |
| FAM83B | FAM83B | Q5T0W9 | Protein FAM83B | chr6 | GO:0016298 | Not Cancer Driver | No | 314 | 0.311 | 684 | 219 | 0.32 | 0 |
| GDPD5_ENST00000529721 | GDPD5 | Q8WTR4 | Glycerophosphodiester phosphodiesterase domain-containing protein 5 | chr11 | GO:0016298 | Not Cancer Driver | No | 74 | 0.122 | 65 | 11 | 0.169 | 0 |
| GPLD1 | GPLD1 | P80108 | Phosphatidylinositol-glycan-specific phospholipase D | chr6 | GO:0016298 | Not Cancer Driver | No | 153 | 0.182 | 36 | 9 | 0.25 | 0 |
| HMOX1 | HMOX1 | P09601 | Heme oxygenase 1 | chr22 | GO:0016298 | Not Cancer Driver | No | 46 | 0.16 | 81 | 13 | 0.16 | 0 |
| HRASLS2 | PLAAT2 | Q9NWW9 | Phospholipase A and acyltransferase 2 | chr11 | GO:0016298 | Not Cancer Driver | No | 24 | 0.148 | 16 | 2 | 0.125 | 0 |
| HRASLS5 | PLAAT5 | Q96KN8 | Phospholipase A and acyltransferase 5 | chr11 | GO:0016298 | Not Cancer Driver | No | 41 | 0.147 | 127 | 12 | 0.094 | 0 |
| LDAH | LDAH | Q9H6V9 | Lipid droplet-associated hydrolase | chr2 | GO:0016298 | Not Cancer Driver | No | 46 | 0.142 | 9 | 0 | 0.0 | 0 |
| LIPA | LIPA | P38571 | Lysosomal acid lipase/cholesteryl ester hydrolase | chr10 | GO:0016298 | Not Cancer Driver | No | 44 | 0.11 | 12 | 1 | 0.083 | 4 |
| LIPC_ENST00000356113 | LIPC | P11150 | Hepatic triacylglycerol lipase | chr15 | GO:0016298 | Not Cancer Driver | No | 91 | 0.182 | 17 | 3 | 0.176 | 2 |
| LIPE | LIPE | Q05469 | Hormone-sensitive lipase | chr19 | GO:0016298 | Not Cancer Driver | No | 123 | 0.114 | 496 | 65 | 0.131 | 0 |
| LIPG | LIPG | Q9Y5X9 | Endothelial lipase | chr18 | GO:0016298 | Not Cancer Driver | No | 90 | 0.18 | 59 | 7 | 0.119 | 0 |
| LIPH | LIPH | Q8WWY8 | Lipase member H | chr3 | GO:0016298 | Not Cancer Driver | No | 71 | 0.157 | 32 | 8 | 0.25 | 2 |
| LIPI_ENST00000536861 | LIPI | Q6XZB0 | Lipase member I | chr21 | GO:0016298 | Not Cancer Driver | No | 142 | 0.309 | 5 | 0 | 0.0 | 1 |
| LIPK | LIPK | Q5VXJ0 | Lipase member K | chr10 | GO:0016298 | Not Cancer Driver | No | 44 | 0.11 | 0 | 0 | 0.0 | 0 |
| LIPM | LIPM | Q5VYY2 | Lipase member M | chr10 | GO:0016298 | Not Cancer Driver | No | 18 | 0.043 | 13 | 0 | 0.0 | 0 |
| LIPN | LIPN | Q5VXI9 | Lipase member N | chr10 | GO:0016298 | Not Cancer Driver | No | 53 | 0.133 | 8 | 1 | 0.125 | 0 |
| LPL | LPL | P06858 | Lipoprotein lipase | chr8 | GO:0016298 | Not Cancer Driver | No | 94 | 0.198 | 23 | 3 | 0.13 | 70 |
| LYPLA1 | LYPLA1 | O75608 | Acyl-protein thioesterase 1 | chr8 | GO:0016298 | Not Cancer Driver | No | 19 | 0.083 | 12 | 2 | 0.167 | 0 |
| MGLL_ENST00000434178 | MGLL | Q99685 | Monoglyceride lipase | chr3 | GO:0016298 | Not Cancer Driver | No | 54 | 0.178 | 29 | 8 | 0.276 | 0 |
| NAPEPLD | NAPEPLD | Q6IQ20 | N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D | chr7 | GO:0016298 | Not Cancer Driver | No | 55 | 0.14 | 76 | 7 | 0.092 | 0 |
| PLA1A | PLA1A | Q53H76 | Phospholipase A1 member A | chr3 | GO:0016298 | Not Cancer Driver | No | 94 | 0.206 | 10 | 0 | 0.0 | 0 |
| PLA2G10 | PLA2G10 | O15496 | Group 10 secretory phospholipase A2 | chr16 | GO:0016298 | Not Cancer Driver | No | 5 | 0.03 | 0 | 0 | 0.0 | 0 |
| PLA2G12A | PLA2G12A | Q9BZM1 | Group XIIA secretory phospholipase A2 | chr4 | GO:0016298 | Not Cancer Driver | No | 18 | 0.095 | 0 | 0 | 0.0 | 0 |
| PLA2G15 | PLA2G15 | Q8NCC3 | Phospholipase A2 group XV | chr16 | GO:0016298 | Not Cancer Driver | No | 61 | 0.148 | 11 | 3 | 0.273 | 0 |
| PLA2G16 | PLAAT3 | P53816 | Phospholipase A and acyltransferase 3 | chr11 | GO:0016298 | Not Cancer Driver | No | 16 | 0.099 | 13 | 1 | 0.077 | 0 |
| PLA2G1B | PLA2G1B | P04054 | Phospholipase A2 | chr12 | GO:0016298 | Not Cancer Driver | No | 17 | 0.115 | 0 | 0 | 0.0 | 0 |
| PLA2G2A_ENST00000375111 | PLA2G2A | P14555 | Phospholipase A2, membrane associated | chr1 | GO:0016298 | Not Cancer Driver | No | 25 | 0.174 | 0 | 0 | 0.0 | 0 |
| PLA2G2C_ENST00000429261 | PLA2G2C | Q5R387 | Putative inactive group IIC secretory phospholipase A2 | chr1 | GO:0016298 | Not Cancer Driver | No | 18 | 0.121 | 10 | 0 | 0.0 | 0 |
| PLA2G2D | PLA2G2D | Q9UNK4 | Group IID secretory phospholipase A2 | chr1 | GO:0016298 | Not Cancer Driver | No | 27 | 0.186 | 0 | 0 | 0.0 | 0 |
| PLA2G2E | PLA2G2E | Q9NZK7 | Group IIE secretory phospholipase A2 | chr1 | GO:0016298 | Not Cancer Driver | No | 33 | 0.232 | 0 | 0 | 0.0 | 0 |
| PLA2G3 | PLA2G3 | Q9NZ20 | Group 3 secretory phospholipase A2 | chr22 | GO:0016298 | Not Cancer Driver | No | 115 | 0.226 | 175 | 39 | 0.223 | 0 |
| PLA2G4A | PLA2G4A | P47712 | Cytosolic phospholipase A2 | chr1 | GO:0016298 | Not Cancer Driver | No | 149 | 0.199 | 129 | 28 | 0.217 | 1 |
| PLA2G4B_ENST00000458483 | PLA2G4B | P0C869 | Cytosolic phospholipase A2 beta | chr15 | GO:0016298 | Not Cancer Driver | No | 88 | 0.113 | 144 | 18 | 0.125 | 0 |
| PLA2G4C_ENST00000599921 | PLA2G4C | Q9UP65 | Cytosolic phospholipase A2 gamma | chr19 | GO:0016298 | Not Cancer Driver | No | 107 | 0.198 | 62 | 9 | 0.145 | 0 |
| PLA2G4D | PLA2G4D | Q86XP0 | Cytosolic phospholipase A2 delta | chr15 | GO:0016298 | Not Cancer Driver | No | 115 | 0.141 | 172 | 17 | 0.099 | 0 |
| PLA2G4E | PLA2G4E | Q3MJ16 | Cytosolic phospholipase A2 epsilon | chr15 | GO:0016298 | Not Cancer Driver | No | 71 | 0.082 | 123 | 6 | 0.049 | 0 |
| PLA2G4F | PLA2G4F | Q68DD2 | Cytosolic phospholipase A2 zeta | chr15 | GO:0016298 | Not Cancer Driver | No | 121 | 0.143 | 106 | 6 | 0.057 | 0 |
| PLA2G5 | PLA2G5 | P39877 | Phospholipase A2 group V | chr1 | GO:0016298 | Not Cancer Driver | No | 24 | 0.174 | 0 | 0 | 0.0 | 2 |
| PLA2G6 | PLA2G6 | O60733 | 85/88 kDa calcium-independent phospholipase A2 | chr22 | GO:0016298 | Not Cancer Driver | No | 108 | 0.134 | 148 | 23 | 0.155 | 11 |
| PLA2G7 | PLA2G7 | Q13093 | Platelet-activating factor acetylhydrolase | chr6 | GO:0016298 | Not Cancer Driver | No | 70 | 0.159 | 27 | 7 | 0.259 | 2 |
| PLB1 | PLB1 | Q6P1J6 | Phospholipase B1, membrane-associated | chr2 | GO:0016298 | Not Cancer Driver | No | 223 | 0.153 | 399 | 57 | 0.143 | 0 |
| PLCB1 | PLCB1 | Q9NQ66 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 | chr20 | GO:0016298 | Not Cancer Driver | No | 313 | 0.257 | 481 | 104 | 0.216 | 0 |
| PLCB2 | PLCB2 | Q00722 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 | chr15 | GO:0016298 | Not Cancer Driver | No | 161 | 0.136 | 495 | 51 | 0.103 | 0 |
| PLCB3 | PLCB3 | Q01970 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 | chr11 | GO:0016298 | Not Cancer Driver | No | 144 | 0.117 | 595 | 68 | 0.114 | 1 |
| PLCB4_ENST00000278655 | PLCB4 | Q15147 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 | chr20 | GO:0016298 | Compendium | Yes | 338 | 0.288 | 401 | 120 | 0.299 | 5 |
| PLCD1_ENST00000334661 | PLCD1 | P51178 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 | chr3 | GO:0016298 | Not Cancer Driver | No | 94 | 0.124 | 111 | 13 | 0.117 | 2 |
| PLCD3 | PLCD3 | Q8N3E9 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 | chr17 | GO:0016298 | Not Cancer Driver | No | 61 | 0.077 | 229 | 22 | 0.096 | 0 |
| PLCD4_ENST00000417849 | PLCD4 | Q9BRC7 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 | chr2 | GO:0016298 | Not Cancer Driver | No | 78 | 0.102 | 90 | 5 | 0.056 | 0 |
| PLCE1 | PLCE1 | Q9P212 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 | chr10 | GO:0016298 | Not Cancer Driver | No | 367 | 0.159 | 780 | 107 | 0.137 | 1 |
| PLCG1_ENST00000373271 | PLCG1 | P19174 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | chr20 | GO:0016298 | Census, Compendium | Yes | 158 | 0.122 | 186 | 21 | 0.113 | 0 |
| PLCG2 | PLCG2 | P16885 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 | chr16 | GO:0016298 | Not Cancer Driver | No | 248 | 0.196 | 142 | 30 | 0.211 | 1 |
| PLCH1 | PLCH1 | Q4KWH8 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 | chr3 | GO:0016298 | Not Cancer Driver | No | 383 | 0.226 | 772 | 195 | 0.253 | 0 |
| PLCH2 | PLCH2 | O75038 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2 | chr1 | GO:0016298 | Not Cancer Driver | No | 145 | 0.102 | 786 | 71 | 0.09 | 0 |
| PLCL1 | PLCL1 | Q15111 | Inactive phospholipase C-like protein 1 | chr2 | GO:0016298 | Not Cancer Driver | No | 258 | 0.236 | 205 | 33 | 0.161 | 0 |
| PLCL2 | PLCL2 | Q9UPR0 | Inactive phospholipase C-like protein 2 | chr3 | GO:0016298 | Not Cancer Driver | No | 185 | 0.164 | 274 | 31 | 0.113 | 0 |
| PLCZ1 | PLCZ1 | Q86YW0 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 | chr12 | GO:0016298 | Not Cancer Driver | No | 151 | 0.248 | 37 | 20 | 0.541 | 1 |
| PLD1 | PLD1 | Q13393 | Phospholipase D1 | chr3 | GO:0016298 | Not Cancer Driver | No | 181 | 0.169 | 133 | 32 | 0.241 | 1 |
| PLD2 | PLD2 | O14939 | Phospholipase D2 | chr17 | GO:0016298 | Not Cancer Driver | No | 107 | 0.115 | 97 | 8 | 0.082 | 0 |
| PLD3_ENST00000409735 | PLD3 | Q8IV08 | 5'-3' exonuclease PLD3 | chr19 | GO:0016298 | Not Cancer Driver | No | 70 | 0.143 | 62 | 7 | 0.113 | 0 |
| PLD4_ENST00000392593 | PLD4 | Q96BZ4 | 5'-3' exonuclease PLD4 | chr14 | GO:0016298 | Not Cancer Driver | No | 46 | 0.091 | 76 | 10 | 0.132 | 0 |
| PLD6 | PLD6 | Q8N2A8 | Mitochondrial cardiolipin hydrolase | chr17 | GO:0016298 | Not Cancer Driver | No | 27 | 0.107 | 24 | 6 | 0.25 | 0 |
| PNLIP | PNLIP | P16233 | Pancreatic triacylglycerol lipase | chr10 | GO:0016298 | Not Cancer Driver | No | 124 | 0.267 | 32 | 11 | 0.344 | 1 |
| PNLIPRP1_ENST00000358834 | PNLIPRP1 | P54315 | Inactive pancreatic lipase-related protein 1 | chr10 | GO:0016298 | Not Cancer Driver | No | 92 | 0.197 | 48 | 10 | 0.208 | 0 |
| PNLIPRP2 | PNLIPRP2 | P54317 | Pancreatic lipase-related protein 2 | chr10 | GO:0016298 | Not Cancer Driver | No | 75 | 0.16 | 28 | 2 | 0.071 | 0 |
| PNLIPRP3 | PNLIPRP3 | Q17RR3 | Pancreatic lipase-related protein 3 | chr10 | GO:0016298 | Not Cancer Driver | No | 129 | 0.276 | 0 | 0 | 0.0 | 0 |
| PNPLA2 | PNPLA2 | Q96AD5 | Patatin-like phospholipase domain-containing protein 2 | chr11 | GO:0016298 | Not Cancer Driver | No | 35 | 0.069 | 101 | 4 | 0.04 | 1 |
| PNPLA3 | PNPLA3 | Q9NST1 | 1-acylglycerol-3-phosphate O-acyltransferase PNPLA3 | chr22 | GO:0016298 | Not Cancer Driver | No | 54 | 0.112 | 33 | 7 | 0.212 | 0 |
| PNPLA8 | PNPLA8 | Q9NP80 | Calcium-independent phospholipase A2-gamma | chr7 | GO:0016298 | Not Cancer Driver | No | 94 | 0.12 | 140 | 18 | 0.129 | 0 |
| PRDX6 | PRDX6 | P30041 | Peroxiredoxin-6 | chr1 | GO:0016298 | Not Cancer Driver | No | 46 | 0.205 | 13 | 4 | 0.308 | 0 |
| RARRES3 | PLAAT4 | Q9UL19 | Phospholipase A and acyltransferase 4 | chr11 | GO:0016298 | Not Cancer Driver | No | 25 | 0.152 | 7 | 1 | 0.143 | 0 |
| SMPD1 | SMPD1 | P17405 | Sphingomyelin phosphodiesterase | chr11 | GO:0016298 | Not Cancer Driver | No | 93 | 0.147 | 51 | 4 | 0.078 | 111 |
| SMPD2 | SMPD2 | O60906 | Sphingomyelin phosphodiesterase 2 | chr6 | GO:0016298 | Not Cancer Driver | No | 45 | 0.106 | 48 | 5 | 0.104 | 0 |
| SMPD3 | SMPD3 | Q9NY59 | Sphingomyelin phosphodiesterase 3 | chr16 | GO:0016298 | Not Cancer Driver | No | 92 | 0.14 | 224 | 29 | 0.129 | 0 |
| SMPD4 | SMPD4 | Q9NXE4 | Sphingomyelin phosphodiesterase 4 | chr2 | GO:0016298 | Not Cancer Driver | No | 114 | 0.132 | 80 | 12 | 0.15 | 1 |
| SMPDL3A | SMPDL3A | Q92484 | Acid sphingomyelinase-like phosphodiesterase 3a | chr6 | GO:0016298 | Not Cancer Driver | No | 56 | 0.124 | 36 | 3 | 0.083 | 0 |
| SMPDL3B | SMPDL3B | Q92485 | Acid sphingomyelinase-like phosphodiesterase 3b | chr1 | GO:0016298 | Not Cancer Driver | No | 61 | 0.134 | 22 | 7 | 0.318 | 0 |