Total number of protein in "GO:0016247" GO term: 82
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKT1_ENST00000349310 | AKT1 | P31749 | RAC-alpha serine/threonine-protein kinase | chr14 | GO:0016247 | Census, Compendium | Yes | 108 | 0.225 | 158 | 24 | 0.152 | 4 |
| AMBP | AMBP | P02760 | Protein AMBP | chr9 | GO:0016247 | Not Cancer Driver | No | 57 | 0.162 | 61 | 15 | 0.246 | 0 |
| ANKRD36C | ANKRD36C | Q5JPF3 | Ankyrin repeat domain-containing protein 36C | chr2 | GO:0016247 | Not Cancer Driver | No | 197 | 0.111 | 1143 | 158 | 0.138 | 0 |
| BCL2_ENST00000333681 | BCL2 | P10415 | Apoptosis regulator Bcl-2 | chr18 | GO:0016247 | Census, Compendium | Yes | 24 | 0.1 | 72 | 5 | 0.069 | 0 |
| BSND | BSND | Q8WZ55 | Barttin | chr1 | GO:0016247 | Not Cancer Driver | No | 57 | 0.178 | 209 | 36 | 0.172 | 4 |
| CACNG2 | CACNG2 | Q9Y698 | Voltage-dependent calcium channel gamma-2 subunit | chr22 | GO:0016247 | Not Cancer Driver | No | 57 | 0.176 | 90 | 16 | 0.178 | 1 |
| CACNG3 | CACNG3 | O60359 | Voltage-dependent calcium channel gamma-3 subunit | chr16 | GO:0016247 | Not Cancer Driver | No | 126 | 0.4 | 69 | 37 | 0.536 | 0 |
| CACNG4 | CACNG4 | Q9UBN1 | Voltage-dependent calcium channel gamma-4 subunit | chr17 | GO:0016247 | Not Cancer Driver | No | 51 | 0.156 | 71 | 17 | 0.239 | 0 |
| CACNG5_ENST00000307139 | CACNG5 | Q9UF02 | Voltage-dependent calcium channel gamma-5 subunit | chr17 | GO:0016247 | Not Cancer Driver | No | 77 | 0.28 | 1 | 0 | 0.0 | 0 |
| CACNG7 | CACNG7 | P62955 | Voltage-dependent calcium channel gamma-7 subunit | chr19 | GO:0016247 | Not Cancer Driver | No | 99 | 0.36 | 9 | 1 | 0.111 | 0 |
| CACNG8 | CACNG8 | Q8WXS5 | Voltage-dependent calcium channel gamma-8 subunit | chr19 | GO:0016247 | Not Cancer Driver | No | 47 | 0.111 | 205 | 15 | 0.073 | 0 |
| CALM1 | CALM1 | P0DP23 | Calmodulin-1 | chr14 | GO:0016247 | Not Cancer Driver | No | 19 | 0.128 | 115 | 15 | 0.13 | 7 |
| CALM2 | CALM2 | P0DP24 | Calmodulin-2 | chr2 | GO:0016247 | Not Cancer Driver | No | 18 | 0.121 | 115 | 13 | 0.113 | 8 |
| CAMK2D_ENST00000342666 | CAMK2D | Q13557 | Calcium/calmodulin-dependent protein kinase type II subunit delta | chr4 | GO:0016247 | Not Cancer Driver | No | 57 | 0.114 | 84 | 10 | 0.119 | 0 |
| CAV1 | CAV1 | Q03135 | Caveolin-1 | chr7 | GO:0016247 | Not Cancer Driver | No | 30 | 0.169 | 2 | 0 | 0.0 | 0 |
| CAV3 | CAV3 | P56539 | Caveolin-3 | chr3 | GO:0016247 | Not Cancer Driver | No | 27 | 0.179 | 0 | 0 | 0.0 | 25 |
| CFTR | CFTR | P13569 | Cystic fibrosis transmembrane conductance regulator | chr7 | GO:0016247 | Not Cancer Driver | No | 287 | 0.194 | 145 | 18 | 0.124 | 151 |
| CHRNA7_ENST00000306901 | CHRNA7 | P36544 | Neuronal acetylcholine receptor subunit alpha-7 | chr15 | GO:0016247 | Not Cancer Driver | No | 71 | 0.141 | 18 | 4 | 0.222 | 0 |
| COMMD1 | COMMD1 | Q8N668 | COMM domain-containing protein 1 | chr2 | GO:0016247 | Not Cancer Driver | No | 21 | 0.111 | 17 | 0 | 0.0 | 0 |
| ENSA_ENST00000369014 | ENSA | O43768 | Alpha-endosulfine | chr1 | GO:0016247 | Not Cancer Driver | No | 15 | 0.124 | 121 | 15 | 0.124 | 0 |
| FGF11 | FGF11 | Q92914 | Fibroblast growth factor 11 | chr17 | GO:0016247 | Not Cancer Driver | No | 20 | 0.089 | 68 | 5 | 0.074 | 0 |
| FGF12 | FGF12 | P61328 | Fibroblast growth factor 12 | chr3 | GO:0016247 | Not Cancer Driver | No | 74 | 0.305 | 102 | 30 | 0.294 | 1 |
| FGF13_ENST00000315930 | FGF13 | Q92913 | Fibroblast growth factor 13 | chrX | GO:0016247 | Not Cancer Driver | No | 70 | 0.286 | 96 | 33 | 0.344 | 2 |
| FGF14_ENST00000376143 | FGF14 | Q92915 | Fibroblast growth factor 14 | chr13 | GO:0016247 | Not Cancer Driver | No | 72 | 0.291 | 93 | 30 | 0.323 | 1 |
| FKBP1A | FKBP1A | P62942 | Peptidyl-prolyl cis-trans isomerase FKBP1A | chr20 | GO:0016247 | Not Cancer Driver | No | 15 | 0.139 | 39 | 7 | 0.179 | 0 |
| FKBP1B | FKBP1B | P68106 | Peptidyl-prolyl cis-trans isomerase FKBP1B | chr2 | GO:0016247 | Not Cancer Driver | No | 10 | 0.093 | 58 | 4 | 0.069 | 0 |
| FXYD1_ENST00000455515 | FXYD1 | O00168 | Phospholemman | chr19 | GO:0016247 | Not Cancer Driver | No | 10 | 0.109 | 22 | 4 | 0.182 | 0 |
| FXYD2 | FXYD2 | P54710 | Sodium/potassium-transporting ATPase subunit gamma | chr11 | GO:0016247 | Not Cancer Driver | No | 2 | 0.03 | 20 | 2 | 0.1 | 1 |
| FXYD3_ENST00000604404 | FXYD3 | Q14802 | FXYD domain-containing ion transport regulator 3 | chr19 | GO:0016247 | Not Cancer Driver | No | 16 | 0.184 | 16 | 1 | 0.062 | 0 |
| FXYD4_ENST00000476166 | FXYD4 | P59646 | FXYD domain-containing ion transport regulator 4 | chr10 | GO:0016247 | Not Cancer Driver | No | 9 | 0.101 | 5 | 1 | 0.2 | 0 |
| FXYD5_ENST00000590686 | FXYD5 | Q96DB9 | FXYD domain-containing ion transport regulator 5 | chr19 | GO:0016247 | Not Cancer Driver | No | 31 | 0.174 | 136 | 18 | 0.132 | 0 |
| FXYD6_ENST00000260282 | FXYD6 | Q9H0Q3 | FXYD domain-containing ion transport regulator 6 | chr11 | GO:0016247 | Not Cancer Driver | No | 14 | 0.147 | 27 | 4 | 0.148 | 0 |
| FXYD7 | FXYD7 | P58549 | FXYD domain-containing ion transport regulator 7 | chr19 | GO:0016247 | Not Cancer Driver | No | 7 | 0.087 | 43 | 2 | 0.047 | 0 |
| GPD1L | GPD1L | Q8N335 | Glycerol-3-phosphate dehydrogenase 1-like protein | chr3 | GO:0016247 | Not Cancer Driver | No | 40 | 0.114 | 13 | 1 | 0.077 | 0 |
| GPLD1 | GPLD1 | P80108 | Phosphatidylinositol-glycan-specific phospholipase D | chr6 | GO:0016247 | Not Cancer Driver | No | 153 | 0.182 | 36 | 9 | 0.25 | 0 |
| ITPR1_ENST00000354582 | ITPR1 | Q14643 | Inositol 1,4,5-trisphosphate receptor type 1 | chr3 | GO:0016247 | Not Cancer Driver | No | 390 | 0.141 | 581 | 76 | 0.131 | 6 |
| KCNMB2_ENST00000452583 | KCNMB2 | Q9Y691 | Calcium-activated potassium channel subunit beta-2 | chr3 | GO:0016247 | Not Cancer Driver | No | 61 | 0.26 | 0 | 0 | 0.0 | 0 |
| KCNV1 | KCNV1 | Q6PIU1 | Potassium voltage-gated channel subfamily V member 1 | chr8 | GO:0016247 | Not Cancer Driver | No | 147 | 0.294 | 30 | 4 | 0.133 | 0 |
| LRRC26 | LRRC26 | Q2I0M4 | Leucine-rich repeat-containing protein 26 | chr9 | GO:0016247 | Not Cancer Driver | No | 3 | 0.009 | 41 | 2 | 0.049 | 0 |
| LRRC38 | LRRC38 | Q5VT99 | Leucine-rich repeat-containing protein 38 | chr1 | GO:0016247 | Not Cancer Driver | No | 24 | 0.082 | 12 | 2 | 0.167 | 0 |
| LRRC52 | LRRC52 | Q8N7C0 | Leucine-rich repeat-containing protein 52 | chr1 | GO:0016247 | Not Cancer Driver | No | 61 | 0.195 | 15 | 4 | 0.267 | 0 |
| MCUB | MCUB | Q9NWR8 | Calcium uniporter regulatory subunit MCUb, mitochondrial | chr4 | GO:0016247 | Not Cancer Driver | No | 33 | 0.098 | 24 | 1 | 0.042 | 0 |
| NEDD4 | NEDD4 | P46934 | E3 ubiquitin-protein ligase NEDD4 | chr15 | GO:0016247 | Not Cancer Driver | No | 150 | 0.114 | 711 | 79 | 0.111 | 0 |
| NEDD4L | NEDD4L | Q96PU5 | E3 ubiquitin-protein ligase NEDD4-like | chr18 | GO:0016247 | Not Cancer Driver | No | 126 | 0.129 | 463 | 60 | 0.13 | 4 |
| NOS1_ENST00000317775 | NOS1 | P29475 | Nitric oxide synthase, brain | chr12 | GO:0016247 | Not Cancer Driver | No | 405 | 0.282 | 342 | 99 | 0.289 | 0 |
| PACSIN3_ENST00000298838 | PACSIN3 | Q9UKS6 | Protein kinase C and casein kinase substrate in neurons protein 3 | chr11 | GO:0016247 | Not Cancer Driver | No | 52 | 0.123 | 290 | 31 | 0.107 | 0 |
| PCSK9 | PCSK9 | Q8NBP7 | Proprotein convertase subtilisin/kexin type 9 | chr1 | GO:0016247 | Not Cancer Driver | No | 86 | 0.124 | 148 | 27 | 0.182 | 9 |
| PDZD3_ENST00000531114 | PDZD3 | Q86UT5 | Na(+)/H(+) exchange regulatory cofactor NHE-RF4 | chr11 | GO:0016247 | Not Cancer Driver | No | 58 | 0.102 | 199 | 19 | 0.095 | 0 |
| PHPT1 | PHPT1 | Q9NRX4 | 14 kDa phosphohistidine phosphatase | chr9 | GO:0016247 | Not Cancer Driver | No | 13 | 0.104 | 6 | 0 | 0.0 | 0 |
| PKP2 | PKP2 | Q99959 | Plakophilin-2 | chr12 | GO:0016247 | Not Cancer Driver | No | 176 | 0.2 | 434 | 98 | 0.226 | 8 |
| PRSS41 | PRSS41 | Q7RTY9 | Serine protease 41 | chr16 | GO:0016247 | Not Cancer Driver | No | 23 | 0.072 | 23 | 2 | 0.087 | 0 |
| PRSS8 | PRSS8 | Q16651 | Prostasin | chr16 | GO:0016247 | Not Cancer Driver | No | 30 | 0.087 | 27 | 3 | 0.111 | 0 |
| PTPN3 | PTPN3 | P26045 | Tyrosine-protein phosphatase non-receptor type 3 | chr9 | GO:0016247 | Not Cancer Driver | No | 139 | 0.152 | 214 | 28 | 0.131 | 0 |
| RACK1 | RACK1 | P63244 | Receptor of activated protein C kinase 1 | chr5 | GO:0016247 | Not Cancer Driver | No | 34 | 0.107 | 13 | 0 | 0.0 | 0 |
| RANGRF | RANGRF | Q9HD47 | Ran guanine nucleotide release factor | chr17 | GO:0016247 | Not Cancer Driver | No | 10 | 0.054 | 42 | 5 | 0.119 | 0 |
| RASA1 | RASA1 | P20936 | Ras GTPase-activating protein 1 | chr5 | GO:0016247 | Compendium | Yes | 154 | 0.147 | 181 | 25 | 0.138 | 3 |
| RSC1A1 | RSC1A1 | Q92681 | Regulatory solute carrier protein family 1 member 1 | chr1 | GO:0016247 | Not Cancer Driver | No | 63 | 0.102 | 548 | 54 | 0.099 | 0 |
| SCLT1 | SCLT1 | Q96NL6 | Sodium channel and clathrin linker 1 | chr4 | GO:0016247 | Not Cancer Driver | No | 98 | 0.142 | 398 | 61 | 0.153 | 0 |
| SCN1B_ENST00000262631 | SCN1B | Q07699 | Sodium channel subunit beta-1 | chr19 | GO:0016247 | Not Cancer Driver | No | 35 | 0.161 | 4 | 1 | 0.25 | 5 |
| SCN2B | SCN2B | O60939 | Sodium channel subunit beta-2 | chr11 | GO:0016247 | Not Cancer Driver | No | 46 | 0.214 | 52 | 7 | 0.135 | 2 |
| SCN3B_ENST00000299333 | SCN3B | Q9NY72 | Sodium channel subunit beta-3 | chr11 | GO:0016247 | Not Cancer Driver | No | 63 | 0.293 | 16 | 5 | 0.312 | 3 |
| SCN4B | SCN4B | Q8IWT1 | Sodium channel subunit beta-4 | chr11 | GO:0016247 | Not Cancer Driver | No | 23 | 0.101 | 46 | 4 | 0.087 | 3 |
| SGK1_ENST00000237305 | SGK1 | O00141 | Serine/threonine-protein kinase Sgk1 | chr6 | GO:0016247 | Census, Compendium | Yes | 58 | 0.135 | 86 | 16 | 0.186 | 0 |
| SGK2_ENST00000373100 | SGK2 | Q9HBY8 | Serine/threonine-protein kinase Sgk2 | chr20 | GO:0016247 | Not Cancer Driver | No | 84 | 0.229 | 52 | 10 | 0.192 | 0 |
| SGK3_ENST00000521198 | SGK3 | Q96BR1 | Serine/threonine-protein kinase Sgk3 | chr8 | GO:0016247 | Not Cancer Driver | No | 54 | 0.109 | 70 | 10 | 0.143 | 0 |
| SLC30A1 | SLC30A1 | Q9Y6M5 | Zinc transporter 1 | chr1 | GO:0016247 | Not Cancer Driver | No | 49 | 0.097 | 144 | 9 | 0.062 | 0 |
| SLC9A3R1 | SLC9A3R1 | O14745 | Na(+)/H(+) exchange regulatory cofactor NHE-RF1 | chr17 | GO:0016247 | Not Cancer Driver | No | 19 | 0.053 | 318 | 16 | 0.05 | 4 |
| SNF8 | SNF8 | Q96H20 | Vacuolar-sorting protein SNF8 | chr17 | GO:0016247 | Not Cancer Driver | No | 30 | 0.116 | 10 | 2 | 0.2 | 0 |
| SNTA1 | SNTA1 | Q13424 | Alpha-1-syntrophin | chr20 | GO:0016247 | Not Cancer Driver | No | 43 | 0.085 | 238 | 14 | 0.059 | 2 |
| STX1A | STX1A | Q16623 | Syntaxin-1A | chr7 | GO:0016247 | Not Cancer Driver | No | 35 | 0.122 | 136 | 11 | 0.081 | 0 |
| STX7 | STX7 | O15400 | Syntaxin-7 | chr6 | GO:0016247 | Not Cancer Driver | No | 29 | 0.111 | 164 | 14 | 0.085 | 0 |
| STX8 | STX8 | Q9UNK0 | Syntaxin-8 | chr17 | GO:0016247 | Not Cancer Driver | No | 32 | 0.136 | 98 | 10 | 0.102 | 0 |
| TMPRSS3_ENST00000433957 | TMPRSS3 | P57727 | Transmembrane protease serine 3 | chr21 | GO:0016247 | Not Cancer Driver | No | 78 | 0.172 | 8 | 3 | 0.375 | 8 |
| TNNI3 | TNNI3 | P19429 | Troponin I, cardiac muscle | chr19 | GO:0016247 | Not Cancer Driver | No | 42 | 0.2 | 108 | 19 | 0.176 | 21 |
| TRPV1_ENST00000399756 | TRPV1 | Q8NER1 | Transient receptor potential cation channel subfamily V member 1 | chr17 | GO:0016247 | Not Cancer Driver | No | 93 | 0.111 | 155 | 18 | 0.116 | 0 |
| VAMP8 | VAMP8 | Q9BV40 | Vesicle-associated membrane protein 8 | chr2 | GO:0016247 | Not Cancer Driver | No | 9 | 0.09 | 27 | 0 | 0.0 | 0 |
| VTI1B | VTI1B | Q9UEU0 | Vesicle transport through interaction with t-SNAREs homolog 1B | chr14 | GO:0016247 | Not Cancer Driver | No | 25 | 0.108 | 192 | 20 | 0.104 | 0 |
| WNK1_ENST00000315939 | WNK1 | Q9H4A3 | Serine/threonine-protein kinase WNK1 | chr12 | GO:0016247 | Not Cancer Driver | No | 278 | 0.117 | 1959 | 223 | 0.114 | 0 |
| WNK2 | WNK2 | Q9Y3S1 | Serine/threonine-protein kinase WNK2 | chr9 | GO:0016247 | Census, Compendium | Yes | 223 | 0.097 | 1868 | 167 | 0.089 | 0 |
| WNK3_ENST00000375159 | WNK3 | Q9BYP7 | Serine/threonine-protein kinase WNK3 | chrX | GO:0016247 | Not Cancer Driver | No | 281 | 0.156 | 1281 | 200 | 0.156 | 0 |
| WNK4 | WNK4 | Q96J92 | Serine/threonine-protein kinase WNK4 | chr17 | GO:0016247 | Compendium | Yes | 178 | 0.143 | 916 | 126 | 0.138 | 4 |
| YWHAH | YWHAH | Q04917 | 14-3-3 protein eta | chr22 | GO:0016247 | Not Cancer Driver | No | 15 | 0.061 | 55 | 3 | 0.055 | 0 |