Total number of protein in "GO:0016242" GO term: 34
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKT1_ENST00000349310 | AKT1 | P31749 | RAC-alpha serine/threonine-protein kinase | chr14 | GO:0016242 | Census, Compendium | Yes | 108 | 0.225 | 158 | 24 | 0.152 | 4 |
| BECN1_ENST00000590099 | BECN1 | Q14457 | Beclin-1 | chr17 | GO:0016242 | Not Cancer Driver | No | 45 | 0.1 | 190 | 19 | 0.1 | 0 |
| CHMP4A_ENST00000609024 | CHMP4A | Q9BY43 | Charged multivesicular body protein 4a | chr14 | GO:0016242 | Not Cancer Driver | No | 24 | 0.108 | 204 | 23 | 0.113 | 0 |
| CHMP4B | CHMP4B | Q9H444 | Charged multivesicular body protein 4b | chr20 | GO:0016242 | Not Cancer Driver | No | 25 | 0.112 | 201 | 22 | 0.109 | 2 |
| CLEC16A | CLEC16A | Q2KHT3 | Protein CLEC16A | chr16 | GO:0016242 | Not Cancer Driver | No | 149 | 0.142 | 374 | 53 | 0.142 | 0 |
| EHMT2_ENST00000375537 | EHMT2 | Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | chr6 | GO:0016242 | Not Cancer Driver | No | 142 | 0.117 | 585 | 71 | 0.121 | 0 |
| FEZ1 | FEZ1 | Q99689 | Fasciculation and elongation protein zeta-1 | chr11 | GO:0016242 | Not Cancer Driver | No | 66 | 0.168 | 277 | 49 | 0.177 | 0 |
| FEZ2_ENST00000405912 | FEZ2 | Q9UHY8 | Fasciculation and elongation protein zeta-2 | chr2 | GO:0016242 | Not Cancer Driver | No | 37 | 0.105 | 245 | 29 | 0.118 | 0 |
| HMOX1 | HMOX1 | P09601 | Heme oxygenase 1 | chr22 | GO:0016242 | Not Cancer Driver | No | 46 | 0.16 | 81 | 13 | 0.16 | 0 |
| LRRK2 | LRRK2 | Q5S007 | Leucine-rich repeat serine/threonine-protein kinase 2 | chr12 | GO:0016242 | Not Cancer Driver | No | 519 | 0.205 | 90 | 17 | 0.189 | 23 |
| LZTS1 | LZTS1 | Q9Y250 | Leucine zipper putative tumor suppressor 1 | chr8 | GO:0016242 | Not Cancer Driver | No | 102 | 0.171 | 467 | 75 | 0.161 | 0 |
| MTM1 | MTM1 | Q13496 | Myotubularin | chrX | GO:0016242 | Not Cancer Driver | No | 112 | 0.186 | 79 | 9 | 0.114 | 57 |
| MTOR | MTOR | P42345 | Serine/threonine-protein kinase mTOR | chr1 | GO:0016242 | Census, Compendium | Yes | 379 | 0.149 | 296 | 37 | 0.125 | 18 |
| NPC1 | NPC1 | O15118 | NPC intracellular cholesterol transporter 1 | chr18 | GO:0016242 | Not Cancer Driver | No | 155 | 0.121 | 24 | 0 | 0.0 | 150 |
| NRBP2 | NRBP2 | Q9NSY0 | Nuclear receptor-binding protein 2 | chr8 | GO:0016242 | Not Cancer Driver | No | 30 | 0.06 | 110 | 5 | 0.045 | 0 |
| NUPR1_ENST00000324873 | NUPR1 | O60356 | Nuclear protein 1 | chr16 | GO:0016242 | Not Cancer Driver | No | 10 | 0.122 | 82 | 10 | 0.122 | 0 |
| PHF23 | PHF23 | Q9BUL5 | PHD finger protein 23 | chr17 | GO:0016242 | Not Cancer Driver | No | 45 | 0.112 | 331 | 37 | 0.112 | 0 |
| PIK3CA | PIK3CA | P42336 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | chr3 | GO:0016242 | Census, Compendium | Yes | 1669 | 1.563 | 38 | 11 | 0.289 | 30 |
| PINK1 | PINK1 | Q9BXM7 | Serine/threonine-protein kinase PINK1, mitochondrial | chr1 | GO:0016242 | Not Cancer Driver | No | 57 | 0.098 | 99 | 13 | 0.131 | 23 |
| POLDIP2 | POLDIP2 | Q9Y2S7 | Polymerase delta-interacting protein 2 | chr17 | GO:0016242 | Not Cancer Driver | No | 36 | 0.098 | 94 | 13 | 0.138 | 0 |
| QSOX1 | QSOX1 | O00391 | Sulfhydryl oxidase 1 | chr1 | GO:0016242 | Not Cancer Driver | No | 93 | 0.124 | 189 | 22 | 0.116 | 0 |
| RNF41_ENST00000615206 | RNF41 | Q9H4P4 | E3 ubiquitin-protein ligase NRDP1 | chr12 | GO:0016242 | Not Cancer Driver | No | 44 | 0.139 | 33 | 2 | 0.061 | 0 |
| RUBCN | RUBCN | Q92622 | Run domain Beclin-1-interacting and cysteine-rich domain-containing protein | chr3 | GO:0016242 | Not Cancer Driver | No | 147 | 0.151 | 403 | 57 | 0.141 | 0 |
| SCFD1 | SCFD1 | Q8WVM8 | Sec1 family domain-containing protein 1 | chr14 | GO:0016242 | Not Cancer Driver | No | 66 | 0.103 | 117 | 12 | 0.103 | 0 |
| SMCR8 | SMCR8 | Q8TEV9 | Guanine nucleotide exchange protein SMCR8 | chr17 | GO:0016242 | Not Cancer Driver | No | 107 | 0.114 | 357 | 38 | 0.106 | 0 |
| SMG1 | SMG1 | Q96Q15 | Serine/threonine-protein kinase SMG1 | chr16 | GO:0016242 | Not Cancer Driver | No | 348 | 0.095 | 605 | 73 | 0.121 | 0 |
| TIGAR | TIGAR | Q9NQ88 | Fructose-2,6-bisphosphatase TIGAR | chr12 | GO:0016242 | Not Cancer Driver | No | 44 | 0.163 | 39 | 9 | 0.231 | 0 |
| TMEM39A | TMEM39A | Q9NV64 | Transmembrane protein 39A | chr3 | GO:0016242 | Not Cancer Driver | No | 53 | 0.109 | 14 | 1 | 0.071 | 0 |
| TP53_ENST00000445888 | TP53 | P04637 | Cellular tumor antigen p53 | chr17 | GO:0016242 | Census, Compendium | Yes | 2891 | 7.356 | 282 | 1466 | 5.199 | 83 |
| TSC1 | TSC1 | Q92574 | Hamartin | chr9 | GO:0016242 | Census, Compendium | Yes | 135 | 0.116 | 732 | 78 | 0.107 | 11 |
| TSC2 | TSC2 | P49815 | Tuberin | chr16 | GO:0016242 | Census, Compendium | Yes | 192 | 0.106 | 563 | 50 | 0.089 | 53 |
| UBQLN4 | UBQLN4 | Q9NRR5 | Ubiquilin-4 | chr1 | GO:0016242 | Not Cancer Driver | No | 70 | 0.116 | 561 | 67 | 0.119 | 1 |
| USP30 | USP30 | Q70CQ3 | Ubiquitin carboxyl-terminal hydrolase 30 | chr12 | GO:0016242 | Not Cancer Driver | No | 76 | 0.147 | 136 | 26 | 0.191 | 0 |
| USP36_ENST00000312010 | USP36 | Q9P275 | Ubiquitin carboxyl-terminal hydrolase 36 | chr17 | GO:0016242 | Not Cancer Driver | No | 151 | 0.134 | 718 | 91 | 0.127 | 0 |